Search of human proteins with 14165397

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
sapiens]
         (807 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1591   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1575   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1240   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1237   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1230   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1229   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1222   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1222   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1217   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1215   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1211   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1211   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1209   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1207   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1207   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1207   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1202   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1201   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1201   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1200   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1200   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1199   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1189   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1189   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1175   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1175   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   798   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   792   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   771   0.0  
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur...   598   e-171

>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1591 bits (4120), Expect = 0.0
 Identities = 807/807 (100%), Positives = 807/807 (100%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
           EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 GSAEGTGQREEDSECLKEVSLYFKKLS 807
           GSAEGTGQREEDSECLKEVSLYFKKLS
Sbjct: 781 GSAEGTGQREEDSECLKEVSLYFKKLS 807


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1575 bits (4077), Expect = 0.0
 Identities = 798/798 (100%), Positives = 798/798 (100%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL
Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP
Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
           EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG
Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR
Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA
Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ
Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL
Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780

Query: 781 GSAEGTGQREEDSECLKE 798
           GSAEGTGQREEDSECLKE
Sbjct: 781 GSAEGTGQREEDSECLKE 798


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1240 bits (3209), Expect = 0.0
 Identities = 632/803 (78%), Positives = 698/803 (86%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           ML SW+  P  + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD  +YFTL
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + + E++ SL LVL+K L+RE+  +H LL+TA DGGKPELTGT QL IT+LDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF   +   ++  F ++P NG
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           +I  KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED+  S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G  GG VSEL+PRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ    GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG  KTDLMAFSPSLPPC 
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSAEGTGQREEDSECLKEVSLYF 803
            S +   +++ D +   +VS ++
Sbjct: 781 ISRDREEKQDVDVDLSAKVSNFY 803


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1237 bits (3201), Expect = 0.0
 Identities = 630/792 (79%), Positives = 692/792 (87%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           ML SW+  P  + LLL LL+LAA E GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDN P+FP + K + I+ESR P +RF L+GASDADIG NS LTY LD  +YFTL
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + + E++ SL LVL+K L+RE+  +H LL+TA DGGKPELTGT QL IT+LDVNDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F +++YKV +LENA NGTLV+ +NATD D+G N DI YSF   +   ++  F ++P NG
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           +I  KG +DFEE K YEI VEA DKGN PM+ HCT+L+E++D+NDN PE+ I SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED+  S +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSV VADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G  GG VSEL+PRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ    GARIPFRVGLYTGEISTTR LDEVDAP HRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSAPPTEG C PGKPTLVCSSA GSWSYSQQR+ RVCSGEG  KTDLMAFSPSLPPC 
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 781 GSAEGTGQREED 792
            S +   +++ D
Sbjct: 781 ISRDREEKQDVD 792


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1230 bits (3182), Expect = 0.0
 Identities = 633/798 (79%), Positives = 687/798 (86%), Gaps = 3/798 (0%)

Query: 4   SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
           SW  G   R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4   SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 64  FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123
           FRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64  FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123

Query: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183
           RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+  
Sbjct: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183

Query: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243
              E +  L L+LRK+LDREE  E  L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F 
Sbjct: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243

Query: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303
           +++YKV +LEN  NGTLVIKLNA+D D+G NGDIVYSF   + P V   F I+P  G+I 
Sbjct: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303

Query: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363
            KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++   SLSLPIRED 
Sbjct: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363

Query: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423
               +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423

Query: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483
           VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483

Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543
           AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543

Query: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603
           PLGSNVTLQVFVLDENDNAPALL P AG  GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603

Query: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663
           NAWLSYELQ    GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663

Query: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
           TVL+SLVESGQAP+ASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723

Query: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSA 783
           SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP    S 
Sbjct: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP---DSR 780

Query: 784 EGTGQREEDSECLKEVSL 801
           +   Q +   E   +VS+
Sbjct: 781 DREDQLQTTEESFAKVSV 798


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1229 bits (3180), Expect = 0.0
 Identities = 628/774 (81%), Positives = 678/774 (87%)

Query: 4   SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63
           SW  G   R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4   SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 64  FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123
           FRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64  FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123

Query: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183
           RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+  
Sbjct: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183

Query: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243
              E +  L L+LRK+LDREE  E  L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F 
Sbjct: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243

Query: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303
           +++YKV +LEN  NGTLVIKLNA+D D+G NGDIVYSF   + P V   F I+P  G+I 
Sbjct: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303

Query: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363
            KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++   SLSLPIRED 
Sbjct: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363

Query: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423
               +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423

Query: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483
           VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483

Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543
           AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543

Query: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603
           PLGSNVTLQVFVLDENDNAPALL P AG  GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603

Query: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663
           NAWLSYELQ    GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663

Query: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
           TVL+SLVESGQAP+ASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723

Query: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777
           SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP
Sbjct: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 615/780 (78%), Positives = 681/780 (87%)

Query: 5   WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
           W+G     +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5   WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64

Query: 65  RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124
           RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65  RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124

Query: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184
           D+NDNPP+F    +++ ++ESR P++RFPL+GASDAD+G NS LTYRL  +DYF LD  +
Sbjct: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184

Query: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244
             ++   + LVLRK+LDRE+   H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244

Query: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304
           S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF   V   V+  F+I+ N GEI  
Sbjct: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304

Query: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364
           +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364

Query: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424
              +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424

Query: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484
           VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544
           QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544

Query: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604
           LGSNVTLQVFVLDENDNAPALL P  G  GG  S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604

Query: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664
           AWLSYELQ AA   RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664

Query: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
           VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784
           A PTEG C  GKPTLVCSSA GSWSYSQQ+  RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1222 bits (3162), Expect = 0.0
 Identities = 615/780 (78%), Positives = 681/780 (87%)

Query: 5   WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64
           W+G     +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF
Sbjct: 5   WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64

Query: 65  RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124
           RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+
Sbjct: 65  RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124

Query: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184
           D+NDNPP+F    +++ ++ESR P++RFPL+GASDAD+G NS LTYRL  +DYF LD  +
Sbjct: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184

Query: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244
             ++   + LVLRK+LDRE+   H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q
Sbjct: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244

Query: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304
           S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF   V   V+  F+I+ N GEI  
Sbjct: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304

Query: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364
           +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q
Sbjct: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364

Query: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424
              +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV
Sbjct: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424

Query: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484
           VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA
Sbjct: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484

Query: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544
           QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP
Sbjct: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544

Query: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604
           LGSNVTLQVFVLDENDNAPALL P  G  GG  S+L+PRSVGAGHVVAKVRAVDADSGYN
Sbjct: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604

Query: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664
           AWLSYELQ AA   RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT
Sbjct: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664

Query: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724
           VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS
Sbjct: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724

Query: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784
           A PTEG C  GKPTLVCSSA GSWSYSQQ+  RVCSGEGP KTDLMAFSP LPP LGS +
Sbjct: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1217 bits (3148), Expect = 0.0
 Identities = 618/790 (78%), Positives = 684/790 (86%), Gaps = 3/790 (0%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK   D
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
           P  ++R++I ESR P++ FPL+GASDAD+G NS LTY+L  ++YF LD + + +    + 
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           L+L+K+LDREE   H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           NA NGT VI+LNA+D D+G NG I YSF   V   V+  F+I+ N GEI  +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
            LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q   +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
           SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
           FVLDENDNAPALL P  G  GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
            A  AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
           QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC 
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733

Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790
             KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC   +G AE     E
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793

Query: 791 EDSECLKEVS 800
           +    + E S
Sbjct: 794 DHDAKVSEFS 803


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1215 bits (3144), Expect = 0.0
 Identities = 616/781 (78%), Positives = 681/781 (87%), Gaps = 3/781 (0%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK   D
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
           P  ++R++I ESR P++ FPL+GASDAD+G NS LTY+L  ++YF LD + + +    + 
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           L+L+K+LDREE   H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           NA NGT VI+LNA+D D+G NG I YSF   V   V+  F+I+ N GEI  +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
            LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q   +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
           SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
           FVLDENDNAPALL P  G  GG VSEL+PRS+GAG VVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
            A  AR PFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL+SLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
           QAP+ASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGAC 
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733

Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC---LGSAEGTGQRE 790
             KPTLVCSSA GSWSYSQQRR RVCSGEGP K DLMAFSPSL PC   +G AE     E
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793

Query: 791 E 791
           +
Sbjct: 794 D 794


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 619/785 (78%), Positives = 687/785 (87%), Gaps = 5/785 (0%)

Query: 7   GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           G PR   L LWLL+L  WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 10  GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126
           ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126

Query: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186
           NDNPP+F   +++++IAES+  ++RFPL+GASDADI  N+ LTYRL  N+YF+LD+  + 
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186

Query: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246
           +Q+  LSL+L+K+LDRE+  E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S 
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246

Query: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
           YKV+++ENA   TLV+KLNATD D+G NG++ YS    + P   + FT++ NNGE+R  G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305

Query: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
            LD+EE K Y+I V+A DKG  PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365

Query: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
            +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425

Query: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486
           ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546
           NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL 
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545

Query: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALL   AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605

Query: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666
           LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665

Query: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           +SLVESGQAP+ASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725

Query: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786
           PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP  L   E  
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE-E 784

Query: 787 GQREE 791
           G+R+E
Sbjct: 785 GERQE 789


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 619/785 (78%), Positives = 687/785 (87%), Gaps = 5/785 (0%)

Query: 7   GGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66
           G PR   L LWLL+L  WE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV
Sbjct: 10  GTPR---LQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66

Query: 67  ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDI 126
           ASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV V+V+DI
Sbjct: 67  ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126

Query: 127 NDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSL 186
           NDNPP+F   +++++IAES+  ++RFPL+GASDADI  N+ LTYRL  N+YF+LD+  + 
Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186

Query: 187 EQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSV 246
           +Q+  LSL+L+K+LDRE+  E +LLLTA+DGGKPELTGTV+LL+ +LDVNDN PEF +S 
Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246

Query: 247 YKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKG 306
           YKV+++ENA   TLV+KLNATD D+G NG++ YS    + P   + FT++ NNGE+R  G
Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNG 305

Query: 307 KLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPS 366
            LD+EE K Y+I V+A DKG  PMAGHCT+ VE+LD NDN+PEV +TSLSLP+RED QPS
Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365

Query: 367 AIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426
            +IALISVSDRDSG NGQVTC+LTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT
Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425

Query: 427 ARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQE 486
           ARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQE
Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLG 546
           NALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPL 
Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545

Query: 547 SNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALL   AGSAGG V++L+PRSVGAGHVVAKVRAVDADSGYNAW
Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605

Query: 607 LSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVL 666
           LSYELQ AA G+RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATATVL
Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665

Query: 667 LSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP 726
           +SLVESGQAP+ASSR  AGA  PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA 
Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725

Query: 727 PTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGT 786
           PTEGACAPGKPTLVCS A GSWSYSQQRR RVCS EGP KTDLMAFSPSLP  L   E  
Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEE-E 784

Query: 787 GQREE 791
           G+R+E
Sbjct: 785 GERQE 789


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1209 bits (3127), Expect = 0.0
 Identities = 630/801 (78%), Positives = 688/801 (85%), Gaps = 2/801 (0%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M SS + G      LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDNPPIFP + K I   ESR  ++RFPL+GASDADIGVN+ L+Y+L  +++F L
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D Q + E   SLSLVL K+LDREE  E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F QSVYKV +LEN  NGTLV+KLNA+D D+G N +IVYS    V   +   FTI+P +G
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIRTKGKLD+EE K YEI V A DKG   M+GHC + ++++D+NDN PEV+ITSLSLPI 
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           E+     +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQL    ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL    
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780

Query: 781 GSAEGTGQREEDSECLKEVSL 801
            SAE   ++  +SE + +VSL
Sbjct: 781 DSAE--EKQLSESEYVGKVSL 799


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1207 bits (3124), Expect = 0.0
 Identities = 618/792 (78%), Positives = 679/792 (85%), Gaps = 1/792 (0%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+ S +G    R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASK  GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V V+DINDNPP F   ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
           EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F   V   V   F IN N G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EI+  G+LD+E+   YEI+++A+DK   P++GHC ++V++LDVNDN PE+ IT+L LP++
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED   S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G  GG VSEL+PRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ A   ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSA PTE  C  GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP   
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779

Query: 781 GSAEGTGQREED 792
            S +   Q   D
Sbjct: 780 TSTDNPRQPNPD 791


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1207 bits (3122), Expect = 0.0
 Identities = 625/784 (79%), Positives = 678/784 (86%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M SS + G      LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV
Sbjct: 1   MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDNPPIFP + K I   ESR  ++RFPL+GASDADIGVN+ L+Y+L  +++F L
Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D Q + E   SLSLVL K+LDREE  E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P
Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F QSVYKV +LEN  NGTLV+KLNA+D D+G N +IVYS    V   +   FTI+P +G
Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIRTKGKLD+EE K YEI V A DKG   M+GHC + ++++D+NDN PEV+ITSLSLPI 
Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           E+     +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQL    ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRA  GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL    
Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780

Query: 781 GSAE 784
            SAE
Sbjct: 781 DSAE 784


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1207 bits (3122), Expect = 0.0
 Identities = 615/777 (79%), Positives = 675/777 (86%), Gaps = 1/777 (0%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+ S +G    R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASK  GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE
Sbjct: 60  PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V V+DINDNPP F   ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L
Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP
Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
           EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F   V   V   F IN N G
Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EI+  G+LD+E+   YEI+++A+DK   P++GHC ++V++LDVNDN PE+ IT+L LP++
Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED   S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS 
Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+
Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+
Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G  GG VSEL+PRSVGAGHVVAKVRAVD D
Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ A   ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT
Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777
           LRCSA PTE  C  GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP
Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP 776


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1202 bits (3110), Expect = 0.0
 Identities = 617/784 (78%), Positives = 672/784 (85%)

Query: 9   PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           P  R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   
Sbjct: 9   PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128
           K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69  KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128

Query: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188
           NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD   S +Q
Sbjct: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188

Query: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248
           +  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y 
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248

Query: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308
           V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G I   G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308

Query: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368
           DFEE + ++I VEAVDKG  P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP  +
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368

Query: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488
           DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488

Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548
           LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL P  G  GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668
           YELQ  A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668

Query: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAP+ASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728

Query: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788
           EGAC+  KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP    S +   Q
Sbjct: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQ 788

Query: 789 REED 792
              D
Sbjct: 789 PNPD 792


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1201 bits (3108), Expect = 0.0
 Identities = 622/804 (77%), Positives = 683/804 (84%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+ S +GG   R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           VKV+DINDNPP+F   ++ I I ESR   +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + S E   SL L LRK LDREE  E  LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F Q+VY+V +LE   NGTLV  LNA+D D+G NG++V+SF   +   +   F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIR   KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED   S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G   G VSEL+PR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D   +RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRAS G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCS PPTEGA  PGKPTLVCSSA GSWS SQQRR RVCS EGP KTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSAEGTGQREEDSECLKEVSLYFK 804
            ++E   Q E + +    VS  F+
Sbjct: 781 NTSERNEQPEANLDLSGNVSPTFE 804


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1201 bits (3107), Expect = 0.0
 Identities = 615/781 (78%), Positives = 671/781 (85%)

Query: 9   PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68
           P  R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   
Sbjct: 9   PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68

Query: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128
           K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69  KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128

Query: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188
           NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD   S +Q
Sbjct: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188

Query: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248
           +  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y 
Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248

Query: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308
           V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G I   G +
Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308

Query: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368
           DFEE + ++I VEAVDKG  P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP  +
Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368

Query: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428
           I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488
           DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488

Query: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548
           LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL P  G  GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668
           YELQ  A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668

Query: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728
           LVESGQAP+ASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728

Query: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788
           EGAC+  KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP    S +    
Sbjct: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNVSH 788

Query: 789 R 789
           +
Sbjct: 789 K 789


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 618/799 (77%), Positives = 678/799 (84%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           ML S +G P  + LLL LLILA W  GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D   S +Q+  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F +++Y V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
            I   G +DFEE + ++I VEAVDKG  P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED Q   +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTP      G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ     A IPFRVGLYTGEISTTR LDE DAP  RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP++SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSAEGTGQREEDSECLKEV 799
           GS E TG+    S+   +V
Sbjct: 781 GSTERTGEPSASSDSTGKV 799


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1200 bits (3104), Expect = 0.0
 Identities = 617/794 (77%), Positives = 676/794 (85%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           ML S +G P  + LLL LLILA W  GSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLF++ SK  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           V+V+DINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D   S +Q+  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F +++Y V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
            I   G +DFEE + ++I VEAVDKG  P+AGHCTLLVEV+DVNDNAP++TI +LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED Q   +IALISV D D+ +NGQVTC+LTPHVPFKLVSTYKNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLTP      G VSE++ RSVGAG VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ     A IPFRVGLYTGEISTTR LDE DAP  RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP++SSRAS GA GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCSA PTEG CAPGKPTLVCSSA GSWSYSQQRR RVCSGEG  KTDLMAFSP L PC 
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 781 GSAEGTGQREEDSE 794
           GS E TG+    S+
Sbjct: 781 GSTERTGEPSASSD 794


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1199 bits (3103), Expect = 0.0
 Identities = 619/790 (78%), Positives = 677/790 (85%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+ S +GG   R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           VKV+DINDNPP+F   ++ I I ESR   +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + S E   SL L LRK LDREE  E  LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F Q+VY+V +LE   NGTLV  LNA+D D+G NG++V+SF   +   +   F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIR   KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED   S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARD+
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL P  G   G VSEL+PR VGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQ AA GARIPFRVGLYTGEISTTR LDE D   +RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVL+SLVESGQAP+ASSRAS G  GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780
           LRCS PPTEGA  PGKPTLVCSSA GSWS SQQRR RVCS EGP KTDLMAFSP L P L
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 GSAEGTGQRE 790
            ++E   Q E
Sbjct: 781 NTSERNEQPE 790


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1189 bits (3076), Expect = 0.0
 Identities = 611/769 (79%), Positives = 666/769 (86%)

Query: 8   GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           GP  ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127
           SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187
           DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L  N+ F L  +   +
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187

Query: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247
           +     LVLRK LDRE+  + +LLL   DGGKPELTG+VQ+ IT+LDVNDN P F +  Y
Sbjct: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247

Query: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307
           KV + EN  N T VI+LNA+DPD+G NG+I Y  +  +  +    F+INP+ GEIR  G+
Sbjct: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307

Query: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367
           LDFEE   YEI V A+DKG   MAGH  +LVEVLDVNDN PEV +TSLSLP++ED Q   
Sbjct: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367

Query: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
           +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487
           RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547
           ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL   AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667
           SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667

Query: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
           SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776
           T   CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1189 bits (3076), Expect = 0.0
 Identities = 611/769 (79%), Positives = 666/769 (86%)

Query: 8   GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           GP  ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127
           SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187
           DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L  N+ F L  +   +
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187

Query: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247
           +     LVLRK LDRE+  + +LLL   DGGKPELTG+VQ+ IT+LDVNDN P F +  Y
Sbjct: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247

Query: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307
           KV + EN  N T VI+LNA+DPD+G NG+I Y  +  +  +    F+INP+ GEIR  G+
Sbjct: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307

Query: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367
           LDFEE   YEI V A+DKG   MAGH  +LVEVLDVNDN PEV +TSLSLP++ED Q   
Sbjct: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367

Query: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427
           +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487
           RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547
           ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS
Sbjct: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL   AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667
           SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+
Sbjct: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667

Query: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727
           SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP
Sbjct: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776
           T   CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL
Sbjct: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1175 bits (3039), Expect = 0.0
 Identities = 605/766 (78%), Positives = 659/766 (86%), Gaps = 1/766 (0%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
             +++++ I ESR  ++RFPL+GASDAD+G N+ LTY+L PN+YF LD  N  ++     
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           LVLRK LDREE  +  LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           N  N TLVI+LNA+D D+G N +++YSF   V P +   F IN   GEI+    +DFE+ 
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
             YEI V+  DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q   +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
            LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552

Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
           FVLDENDNAPALL   AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612

Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
           AAVGARIPFRVGLYTGEISTTR LDE D+P  RLLVLVKDHGEP+LTATATVL+SLVE  
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672

Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
           QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731

Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC 779
           P KPTLVCSSA GSWSYSQQRR RVCSGEG  K DLMAFSPSLPPC
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1175 bits (3039), Expect = 0.0
 Identities = 605/766 (78%), Positives = 659/766 (86%), Gaps = 1/766 (0%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
             +++++ I ESR  ++RFPL+GASDAD+G N+ LTY+L PN+YF LD  N  ++     
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           LVLRK LDREE  +  LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           N  N TLVI+LNA+D D+G N +++YSF   V P +   F IN   GEI+    +DFE+ 
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
             YEI V+  DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q   +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
            LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552

Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
           FVLDENDNAPALL   AGSAGG VSEL+ RSV AGHVVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612

Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
           AAVGARIPFRVGLYTGEISTTR LDE D+P  RLLVLVKDHGEP+LTATATVL+SLVE  
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672

Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACA 733
           QAP+ASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731

Query: 734 PGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPC 779
           P KPTLVCSSA GSWSYSQQRR RVCSGEG  K DLMAFSPSLPPC
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPC 777


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  798 bits (2060), Expect = 0.0
 Identities = 398/521 (76%), Positives = 455/521 (87%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK   D
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+VRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
           P  ++R++I ESR P++ FPL+GASDAD+G NS LTY+L  ++YF LD + + +    + 
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           L+L+K+LDREE   H+L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F QS Y+V + E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           NA NGT VI+LNA+D D+G NG I YSF   V   V+  F+I+ N GEI  +G LDFE++
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
            LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q   +IALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D DSG+NGQV C+LTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
           SLWATAS+SV VAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  153 bits (386), Expect = 7e-37
 Identities = 108/341 (31%), Positives = 161/341 (47%), Gaps = 21/341 (6%)

Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPF-- 395
           VEV D+NDN P   +    + I E   P ++  L   SD D GSN  +T  L+    F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
             K+ S       L+L  +LDRE   A+ L +TA DGG P L  T  + V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAE 513
            F Q EY V + EN   G  +  ++A D D   N  +SYS     +    +  + S+   
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSA 573
           +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +       A
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEI-------A 351

Query: 574 GGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTGEIS 632
             ++S  +      G V+A +   D DSG N  ++  L        +PF+ V  +    S
Sbjct: 352 LTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLT-----PHVPFKLVSTFKNYYS 406

Query: 633 TT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
                 LD      + L+V  +D G P+L ATA++ + + +
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVAD 447



 Score =  150 bits (380), Expect = 3e-36
 Identities = 117/416 (28%), Positives = 190/416 (45%), Gaps = 19/416 (4%)

Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
           + + D+NDN P F     +V + E+    ++     A+D D G+N  + Y      +  +
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 290 VYAFTINPNNG-EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAP 348
                 + N    +  K  LD EE   + + + A D G   + G   LLV VLDVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 349 EVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTY---KNYY 405
               +   + I E+      +  ++ SDRD G+NG ++ +    V   ++  +   +N  
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300

Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVK 465
            +V+   LD E  + Y++++ A D G P +    +V V + D NDN P  A    ++ V+
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 466 ENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDH 525
           E+   G  I  +S  D D+  N  V+ SL    V  + +S++ + ++    +     LD 
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDR 415

Query: 526 EELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSV 585
           E +   +  V+ARD G P L +  +L V V D NDNAPA   P         +  +  + 
Sbjct: 416 ESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQP-------EYTVFVKENN 468

Query: 586 GAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARI---PFRVGLYTGEISTTRPLD 638
             G  +  V A DAD+  NA +SY L    VG R       V   +G++   +PLD
Sbjct: 469 PPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLD 524


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  792 bits (2045), Expect = 0.0
 Identities = 404/534 (75%), Positives = 455/534 (85%)

Query: 1   MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60
           M+ S +GG   R LLLWLL+LAAWE GSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120
           PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I DRPLQVFHVE
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180
           VKV+DINDNPP+F   ++ I I ESR   +RFP++GA+DADIG N+ LTY L P+DYF+L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240
           D + S E   SL L LRK LDREE  E  LLLTA+DGGKPEL GTV+LLIT+LDVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300
            F Q+VY+V +LE   NGTLV  LNA+D D+G NG++V+SF   +   +   F ++ ++G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360
           EIR   KLD+EE K YEI V+AVDKG+ PM+ HC +LV+VLDVNDNAPE+ +TSL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420
           ED   S +IALI+VSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480
           YELVVTARDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  139 bits (349), Expect = 1e-32
 Identities = 111/344 (32%), Positives = 160/344 (46%), Gaps = 27/344 (7%)

Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKL 397
           V+V D+NDN P        + I E    ++   +   +D D G+N  +T TL+P   F L
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 398 VSTYKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
                +  S    L L   LDRE      L++TA DGG P L  T  + + V DVNDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSL---VERRVGERALSSYVSV 510
            F Q  Y V + E    G  + T++A DAD   N  V +S    + R + E+       V
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKV 295

Query: 511 HAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGA 570
            + SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L     
Sbjct: 296 DSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL---AV 352

Query: 571 GSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTG 629
            S    + E  P S     V+A +   D DSG N  ++  L        +PF+ V  +  
Sbjct: 353 TSLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTFKN 403

Query: 630 EISTT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
             S      LD      + L+V  +D G P+L ATA V + + +
Sbjct: 404 YYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447



 Score =  138 bits (348), Expect = 2e-32
 Identities = 118/420 (28%), Positives = 187/420 (44%), Gaps = 27/420 (6%)

Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
           + + D+NDN P F      + + E+    +      A D D G N  + Y+      P+ 
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLS----PSD 176

Query: 290 VYAFTINPNNGEIRT-----KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVN 344
            ++  +  ++   ++     +  LD EE     + + A D G   + G   LL+ VLDVN
Sbjct: 177 YFSLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVN 236

Query: 345 DNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNY 404
           DNAP        + + E T    ++  ++ SD D G NG+V  +    +   +   +K  
Sbjct: 237 DNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVD 296

Query: 405 YS---LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYT 461
            S   + L   LD E   +YE+ V A D GSP +     V V V DVNDNAP  A     
Sbjct: 297 SSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLY 356

Query: 462 VFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQ 521
           + ++E+ P    I  ++  D D+  N  V+ SL+   V  + +S++ + ++    +    
Sbjct: 357 LPIREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDS 411

Query: 522 PLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELM 581
            LD E L + +  V+ARD G P L +   + V V D NDNAPA   P         +  +
Sbjct: 412 ALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQP-------EYTVFV 464

Query: 582 PRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARI---PFRVGLYTGEISTTRPLD 638
             +   G  +  V A DAD+  NA +SY L    VG R       V   +G++   +PLD
Sbjct: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLD 524


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  771 bits (1992), Expect = 0.0
 Identities = 392/521 (75%), Positives = 440/521 (84%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           LLL LL+LAAWE GSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASKRHGD
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           LLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHV+V+V+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
             +++++ I ESR  ++RFPL+GASDAD+G N+ LTY+L PN+YF LD  N  ++     
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           LVLRK LDREE  +  LLLTA+DGGKPE TG+V LLI +LD NDNAP F + VY+V + E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           N  N TLVI+LNA+D D+G N +++YSF   V P +   F IN   GEI+    +DFE+ 
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
             YEI V+  DKGN PM GHCT+LVE+LD NDN+PEV +TSLSLP++ED Q   +IALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD DSG+NGQVTC+LTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
            LWATASVSV VADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  135 bits (341), Expect = 1e-31
 Identities = 102/341 (29%), Positives = 156/341 (45%), Gaps = 21/341 (6%)

Query: 338 VEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKL 397
           VEV D+NDN P  ++T   L I E     +   L   SD D G N  +T  L+P+  F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 398 VSTYKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAP 453
               K     +  LVL   LDRE     +L++TA DGG P    + S+ + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAE 513
            F +P Y V + EN      +  ++A D+D   N  + YS     +    +     ++  
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297

Query: 514 SGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSA 573
           +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++       
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT----- 352

Query: 574 GGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQLAAVGARIPFR-VGLYTGEIS 632
             ++S  +      G V+A +   D DSG N  ++  L        +PF+ V  Y    S
Sbjct: 353 --SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLT-----PHVPFKLVSTYKNYYS 405

Query: 633 TT--RPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVE 671
                 LD      + L+V  +D G P L ATA+V + + +
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVAD 446



 Score =  130 bits (327), Expect = 5e-30
 Identities = 111/416 (26%), Positives = 190/416 (45%), Gaps = 19/416 (4%)

Query: 230 ITILDVNDNAPEFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAV 289
           + + D+NDN P F  +  K+++ E+    +      A+D D G N  + Y      +  +
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 290 VYAFTINPNNGEIRTKGKL-DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAP 348
                 + +   +    KL D EE    ++ + A D G     G  +LL+ VLD NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 349 EVTITSLSLPIREDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTY---KNYY 405
                   + + E+     ++  ++ SD D G N ++  + +  VP  +   +   +   
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTG 299

Query: 406 SLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVK 465
            + ++ A+D E  + YE+ V   D G+P +    +V V + D NDN+P       ++ VK
Sbjct: 300 EIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVK 359

Query: 466 ENNPPGCHIFTVSAQDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDH 525
           E+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +     LD 
Sbjct: 360 EDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALDR 414

Query: 526 EELELLQFQVSARDSGVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSV 585
           E +   +  V+ARD G PPL +  ++ V V D NDNAPA        A    +  +  + 
Sbjct: 415 ERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKENN 467

Query: 586 GAGHVVAKVRAVDADSGYNAWLSYELQLAAVGAR-IPFRVGLY--TGEISTTRPLD 638
             G  +  V A DAD+  NA +SY L    +G R +   V ++  +G++   +PLD
Sbjct: 468 PPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLD 523



 Score = 85.1 bits (209), Expect = 2e-16
 Identities = 81/272 (29%), Positives = 119/272 (43%), Gaps = 19/272 (6%)

Query: 441 VSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYSLVERRVG 500
           V V V D+NDN P F+  E  + + E+           A DAD  ENAL++Y L      
Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177

Query: 501 ERALSSYVSVHAESGKVYALQPL-DHEELELLQFQVSARDSGVPPLGSNVTLQVFVLDEN 559
              L        +   V  L+ L D EE   L+  ++A D G P    +V+L + VLD N
Sbjct: 178 --VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDAN 235

Query: 560 DNAPALLTPGAGSAGGTVSEL-MPRSVGAGHVVAKVRAVDADSGYNAWLSYELQ-LAAVG 617
           DNAP    P        V E+ M  +     +V ++ A D+D G N  + Y    L    
Sbjct: 236 DNAPIFDRP--------VYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPT 287

Query: 618 ARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLV-ESGQAP 676
            R  F +   TGEI     +D  D+  + + V V D G P +    TVL+ L+ E+  +P
Sbjct: 288 IRRKFWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSP 347

Query: 677 QASSRASAGAVGPEAALVDVNVYLIIAICAVS 708
           +    + +  V       D  V  +IA+ +VS
Sbjct: 348 EVIVTSLSLPVKE-----DAQVGTVIALISVS 374


>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
           [Homo sapiens]
          Length = 820

 Score =  598 bits (1542), Expect = e-171
 Identities = 342/806 (42%), Positives = 481/806 (59%), Gaps = 24/806 (2%)

Query: 14  LLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGD 73
           +LL +L+   WETG  Q+ YSVPEE + G+ VG I++DLGLE  EL  R  R+  +    
Sbjct: 14  VLLGILLGTLWETGCTQIRYSVPEELEKGSRVGDISRDLGLEPRELAERGVRIIPRGRTQ 73

Query: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDINDNPPIF 133
           L  +N ++G L    RIDREELC  + +C ++L+++++  ++++ VEV+VRDINDN P F
Sbjct: 74  LFALNPRSGSLVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYF 133

Query: 134 PESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQMSSLS 193
            ES+  I I+E+   E RFPL  A D DIG NS  +Y L PN +F+L  QN  +      
Sbjct: 134 RESELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYELSPNTHFSLIVQNGADGSKYPE 193

Query: 194 LVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYKVTVLE 253
           LVL++ LDREE   H L+LTASDGG P  TGT ++ + +LD NDNAP F Q  Y+ +V E
Sbjct: 194 LVLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPE 253

Query: 254 NAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKLDFEEK 313
           N   GT ++ +NATDPD+G N ++ YSFR  V       F ++ N+G I T G+LD EE 
Sbjct: 254 NLALGTQLLVVNATDPDEGVNAEVRYSFRY-VDDKAAQVFKLDCNSGTISTIGELDHEES 312

Query: 314 KLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAIIALIS 373
             Y++ V+A+D  N   +    +L+ VLDVNDNAPEV +TSL+  + E++    +IAL++
Sbjct: 313 GFYQMEVQAMD--NAGYSARAKVLITVLDVNDNAPEVVLTSLASSVPENSPRGTLIALLN 370

Query: 374 VSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D+DS  NGQV C +  ++PFKL  +Y NYYSLV D  LDRE V +Y + VTA D G+P
Sbjct: 371 VNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRGTP 430

Query: 434 SLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENALVSYS 493
            L     +S+ VAD NDN P F Q  Y+ ++ ENNP G  + +V+A D D +ENA ++YS
Sbjct: 431 PLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQITYS 490

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSNVTLQV 553
           L E  +   +LSSYVS+++++G +YAL   D+E+   LQ +V ARD+G PPL SNV+L +
Sbjct: 491 LAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSLSL 550

Query: 554 FVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLSYELQL 613
           FVLD+NDNAP +L P   + G T  EL PRS   G++V KV AVD DSG NAWLSY L  
Sbjct: 551 FVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRLLK 610

Query: 614 AAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLSLVESG 673
           A+      F VGL+TGE+ T R L + DA    L+V V+DHG+P L+AT T+ +++ +S 
Sbjct: 611 ASEPGL--FSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADS- 667

Query: 674 QAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR------CSAPP 727
             PQ  +   +      +   D+ +YL++A+ AVS + +  ++L  ALR           
Sbjct: 668 -IPQVLADLGSLESPANSETSDLTLYLVVAVAAVSCVFLAFVILLLALRLRRWHKSRLLQ 726

Query: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTG 787
             G    G P        G  ++ Q     V       K+ L+   P+    L S E   
Sbjct: 727 ASGGGLTGAPASHFVGVDGVQAFLQTYSHEVSLTTDSRKSHLIFPQPNYADMLVSQESFE 786

Query: 788 QRE-----------EDSECLKEVSLY 802
           + E           +DS  L EVSLY
Sbjct: 787 KSEPLLLSGDSVFSKDSHGLIEVSLY 812


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.133    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,105,935
Number of Sequences: 37866
Number of extensions: 1481508
Number of successful extensions: 10667
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 191
Number of HSP's successfully gapped in prelim test: 28
Number of HSP's that attempted gapping in prelim test: 3729
Number of HSP's gapped (non-prelim): 732
length of query: 807
length of database: 18,247,518
effective HSP length: 110
effective length of query: 697
effective length of database: 14,082,258
effective search space: 9815333826
effective search space used: 9815333826
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.