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Search of human proteins with 9966883
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
(1203 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens] 2406 0.0
gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens] 2388 0.0
gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens] 1296 0.0
gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens] 1291 0.0
gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens] 1285 0.0
gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo ... 1183 0.0
gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo s... 1181 0.0
gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens] 1176 0.0
gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens] 1176 0.0
gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens] 748 0.0
gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens] 709 0.0
gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens] 698 0.0
gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens] 697 0.0
gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens] 694 0.0
gi|190194360 protocadherin 20 [Homo sapiens] 656 0.0
gi|14589929 protocadherin 18 precursor [Homo sapiens] 383 e-106
gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precur... 372 e-102
gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precur... 372 e-102
gi|94538350 protocadherin 17 precursor [Homo sapiens] 370 e-102
gi|157426847 protocadherin 19 isoform a [Homo sapiens] 370 e-102
gi|157426845 protocadherin 19 isoform b [Homo sapiens] 370 e-102
gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precurs... 367 e-101
gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precurs... 367 e-101
gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens] 362 1e-99
gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens] 362 1e-99
gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precurs... 362 2e-99
gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precur... 362 2e-99
gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens] 354 3e-97
gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precurs... 353 4e-97
gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precurs... 353 4e-97
>gi|9966883 protocadherin 9 isoform 2 precursor [Homo sapiens]
Length = 1203
Score = 2406 bits (6235), Expect = 0.0
Identities = 1203/1203 (100%), Positives = 1203/1203 (100%)
Query: 1 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 60
MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA
Sbjct: 1 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 60
Query: 61 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 120
SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN
Sbjct: 61 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 120
Query: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
Query: 181 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 240
LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV
Sbjct: 181 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 240
Query: 241 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 300
TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK
Sbjct: 241 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 300
Query: 301 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 360
RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL
Sbjct: 301 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 360
Query: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL
Sbjct: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
Query: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF
Sbjct: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
Query: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 600
TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD
Sbjct: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 600
Query: 601 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 660
AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK
Sbjct: 601 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 660
Query: 661 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 720
VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG
Sbjct: 661 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 720
Query: 721 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN
Sbjct: 721 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Query: 781 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 840
ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH
Sbjct: 781 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 840
Query: 841 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI
Sbjct: 841 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH 1020
HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFH 1020
Query: 1021 LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD 1080
LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD
Sbjct: 1021 LPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSD 1080
Query: 1081 GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV 1140
GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV
Sbjct: 1081 GPLGPRGLAEATEMCTQECLVLGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLV 1140
Query: 1141 NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1200
NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE
Sbjct: 1141 NGHTLTRAWKEDSNRNQFNDRKQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1200
Query: 1201 HQL 1203
HQL
Sbjct: 1201 HQL 1203
>gi|45243534 protocadherin 9 isoform 1 precursor [Homo sapiens]
Length = 1237
Score = 2388 bits (6190), Expect = 0.0
Identities = 1203/1237 (97%), Positives = 1203/1237 (97%), Gaps = 34/1237 (2%)
Query: 1 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 60
MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA
Sbjct: 1 MDLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSA 60
Query: 61 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 120
SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN
Sbjct: 61 SLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN 120
Query: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE
Sbjct: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
Query: 181 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 240
LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV
Sbjct: 181 LLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQV 240
Query: 241 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 300
TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK
Sbjct: 241 TVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK 300
Query: 301 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 360
RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL
Sbjct: 301 RLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDL 360
Query: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL
Sbjct: 361 RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYL 420
Query: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE
Sbjct: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
Query: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF
Sbjct: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
Query: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 600
TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD
Sbjct: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDAD 600
Query: 601 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 660
AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK
Sbjct: 601 AGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAK 660
Query: 661 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 720
VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG
Sbjct: 661 VTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSG 720
Query: 721 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN
Sbjct: 721 NNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
Query: 781 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 840
ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH
Sbjct: 781 ASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRH 840
Query: 841 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI
Sbjct: 841 ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK
Sbjct: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ-------- 1012
HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQ
Sbjct: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLHTRQCNSHSKSD 1020
Query: 1013 --------------------------SQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI 1046
SQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI
Sbjct: 1021 NIPVTPQKCPSSTGFHIQENEESHYESQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLI 1080
Query: 1047 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1106
SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD
Sbjct: 1081 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1140
Query: 1107 NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS 1166
NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS
Sbjct: 1141 NCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDRKQYGS 1200
Query: 1167 NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL 1203
NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL
Sbjct: 1201 NEGHFNNGSHMTDIPLANLKSYKQAGGATESPKEHQL 1237
>gi|14589946 protocadherin 11 Y-linked isoform c [Homo sapiens]
Length = 1340
Score = 1296 bits (3354), Expect = 0.0
Identities = 651/1122 (58%), Positives = 852/1122 (75%), Gaps = 24/1122 (2%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+ C+ S AQE YTIREE+PENV IGN+ KDLN+S I + T+ ++ ++L
Sbjct: 40 YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 97
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 98 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 155
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 156 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 215
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 216 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 275
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 276 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 335
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 336 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++
Sbjct: 396 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 455
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 456 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 515
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
L +SATD DSG NA+I Y LGP+A F LDR+TG+LT + DRE++++++FT+ A+
Sbjct: 516 QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 575
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 576 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 635
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 636 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 695
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PP N S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 696 VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 755
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 756 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 815
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R+++E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 816 ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 873
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++ Q +EW +PN EN+Q KKKK+KK+ SPK+ LLN VTIEE+K DD +
Sbjct: 874 LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 933
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 934 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 991
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRRVTF 1019
HH+IQELPLDNTFV CD++S SS+SSD +S S+C F+ +HTR SQRRVTF
Sbjct: 992 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPSQRRVTF 1050
Query: 1020 HLPDGSQESCSDSGLGDHEPVGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNS 1079
HLP+GSQES SD GLGDH+ GS T SH LPL PQ+E++D+A+P RTE DGNSDP S
Sbjct: 1051 HLPEGSQESSSDGGLGDHD-AGSLTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPES 1109
Query: 1080 DGPLGPR-------GLAEATEMCTQECLVLGHSDNCWMPPGL 1114
G + + EA++ CTQECL+ GHSD CWMP L
Sbjct: 1110 TFIPGLKKEITVQPTVEEASDNCTQECLIYGHSDACWMPASL 1151
>gi|14589922 protocadherin 11 X-linked isoform d [Homo sapiens]
Length = 1337
Score = 1291 bits (3340), Expect = 0.0
Identities = 658/1151 (57%), Positives = 854/1151 (74%), Gaps = 53/1151 (4%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG--IPRDEHCFYEVEVAILPDEIFRLV 123
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTR-------- 1011
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVR 1018
Query: 1012 -------------------QSQRRVTFHLPDGSQESCSDSGLGDHEPVGSGTLISHPLPL 1052
QSQRRVTFHLP+GSQES SD GLGDH+ GS T SH LPL
Sbjct: 1019 SCTPMKESTTMEIWIHPQPQSQRRVTFHLPEGSQESSSDGGLGDHD-AGSLTSTSHGLPL 1077
Query: 1053 VQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLA---------EATEMCTQECLVLG 1103
PQ+E++D+A+P RTE DGNSDP S G + A EA++ CTQECL+ G
Sbjct: 1078 GYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASDNCTQECLIYG 1137
Query: 1104 HSDNCWMPPGL 1114
HSD CWMP L
Sbjct: 1138 HSDACWMPASL 1148
>gi|14589920 protocadherin 11 X-linked isoform c [Homo sapiens]
Length = 1347
Score = 1285 bits (3326), Expect = 0.0
Identities = 657/1161 (56%), Positives = 854/1161 (73%), Gaps = 63/1161 (5%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAG--IPRDEHCFYEVEVAILPDEIFRLV 123
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTR-------- 1011
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPPMKEVVR 1018
Query: 1012 -----------------------------QSQRRVTFHLPDGSQESCSDSGLGDHEPVGS 1042
+SQRRVTFHLP+GSQES SD GLGDH+ GS
Sbjct: 1019 SCTPMKESTTMEIWIHPQPQRKSEGKVAGKSQRRVTFHLPEGSQESSSDGGLGDHD-AGS 1077
Query: 1043 GTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLA---------EATE 1093
T SH LPL PQ+E++D+A+P RTE DGNSDP S G + A EA++
Sbjct: 1078 LTSTSHGLPLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKAAEITVQPTVEEASD 1137
Query: 1094 MCTQECLVLGHSDNCWMPPGL 1114
CTQECL+ GHSD CWMP L
Sbjct: 1138 NCTQECLIYGHSDACWMPASL 1158
>gi|14589918 protocadherin 11 X-linked isoform b precursor [Homo
sapiens]
Length = 1025
Score = 1183 bits (3061), Expect = 0.0
Identities = 593/1019 (58%), Positives = 780/1019 (76%), Gaps = 16/1019 (1%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRRVT 1018
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR + R +
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSRTS 1017
>gi|7657443 protocadherin 11 X-linked isoform a precursor [Homo
sapiens]
Length = 1021
Score = 1181 bits (3056), Expect = 0.0
Identities = 592/1012 (58%), Positives = 777/1012 (76%), Gaps = 16/1012 (1%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+AC+ S AQE YTIREE+PENV IG++ KDLN+S I + T+A + ++L
Sbjct: 8 YIFAVLLACVVFHSG-AQEKNYTIREEMPENVLIGDLLKDLNLSLIPNKSLTTA-MQFKL 65
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 66 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 123
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 124 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 183
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 184 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 243
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 244 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 303
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 304 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 363
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLET++
Sbjct: 364 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLETAAY 423
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 424 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 483
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
LT +SA D DSG NA I Y LGP+A F LD +TG+LT + DRE++++++FT+ A+
Sbjct: 484 QLTKVSAMDADSGPNAKINYLLGPDAPPEFSLDCRTGMLTVVKKLDREKEDKYLFTILAK 543
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN + F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 544 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYNFYVPENLPRHGTVGLITVTDPDYGDNS 603
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 604 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 663
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PPSN S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 664 VDVNDNKPVFIVPPSNCSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 723
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 724 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 783
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R++ E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 784 ELVRKSTEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 841
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++KQ +EW +PN EN+Q KKKK+KK+ SPK+ LLNFVTIEE+K DD +
Sbjct: 842 LKAAQKNKQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNFVTIEETKADDVDSDGN 901
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP++ K
Sbjct: 902 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLN-SK 959
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTR 1011
HH+IQELPLDNTFV CD++SK SS+SSD +S S+C F+ +HTR
Sbjct: 960 HHIIQELPLDNTFV-ACDSISKCSSSSSDPYSVSDCGYPVTTFEVPVSVHTR 1010
>gi|14589944 protocadherin 11 Y-linked isoform b [Homo sapiens]
Length = 1048
Score = 1176 bits (3043), Expect = 0.0
Identities = 588/1017 (57%), Positives = 778/1017 (76%), Gaps = 16/1017 (1%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+ C+ S AQE YTIREE+PENV IGN+ KDLN+S I + T+ ++ ++L
Sbjct: 40 YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 97
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 98 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 155
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 156 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 215
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 216 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 275
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 276 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 335
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 336 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 395
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++
Sbjct: 396 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 455
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 456 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 515
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
L +SATD DSG NA+I Y LGP+A F LDR+TG+LT + DRE++++++FT+ A+
Sbjct: 516 QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 575
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 576 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 635
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 636 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 695
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PP N S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 696 VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 755
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 756 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 815
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R+++E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 816 ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 873
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++ Q +EW +PN EN+Q KKKK+KK+ SPK+ LLN VTIEE+K DD +
Sbjct: 874 LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 933
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 934 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 991
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRR 1016
HH+IQELPLDNTFV CD++S SS+SSD +S S+C F+ +HTR + R
Sbjct: 992 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSR 1047
>gi|14589942 protocadherin 11 Y-linked isoform a [Homo sapiens]
Length = 1037
Score = 1176 bits (3043), Expect = 0.0
Identities = 588/1017 (57%), Positives = 778/1017 (76%), Gaps = 16/1017 (1%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
Y+ A L+ C+ S AQE YTIREE+PENV IGN+ KDLN+S I + T+ ++ ++L
Sbjct: 29 YIFAVLLVCVVFHSG-AQEKNYTIREEIPENVLIGNLLKDLNLSLIPNKSLTT-TMQFKL 86
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
V K GD PL+++ TGEIFTT RIDREKLCAG + CF+E+EV ILP++ FRL+
Sbjct: 87 VYKTGDVPLIRIEEDTGEIFTTGARIDREKLCAGIP--RDEHCFYEVEVAILPDEIFRLV 144
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
KI+ +++D NDNAP+FP+ VINISIPEN+ INS++ +P+A DPD G NGVQ+YEL+ Q+
Sbjct: 145 KIRFLIEDINDNAPLFPATVINISIPENSAINSKYTLPAAVDPDVGINGVQNYELIKSQN 204
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
+FGLD++ETPEG+K PQLIVQ+ LDRE+KDTYVMK+KVEDGG PQ+SSTAILQV+V+D N
Sbjct: 205 IFGLDVIETPEGDKMPQLIVQKELDREEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTN 264
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN PVFKE ++EV IPENAPVGTSV QLHATDADIG NA+I + F V+ +RLF LN
Sbjct: 265 DNHPVFKETEIEVSIPENAPVGTSVTQLHATDADIGENAKIHFSFSNLVSNIARRLFHLN 324
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISP 366
TTGLIT++ LDREET HK+ VLASDG PARA V +NVTDVNDN P+ID+RYI++P
Sbjct: 325 ATTGLITIKEPLDREETPNHKLLVLASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNP 384
Query: 367 INGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSL 426
+N TV LSE P+NTKIALITV+DKD D NG+V CF + E+PF L+ V+ NQ+LLE ++
Sbjct: 385 VNDTVVLSENIPLNTKIALITVTDKDADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAY 444
Query: 427 LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGL 486
LDYE TKE++ K++A+D+GKP LNQ+A++ +K++DENDN P+F Q + +S+ ENN G+
Sbjct: 445 LDYESTKEYAIKLLAADAGKPPLNQSAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGI 504
Query: 487 YLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDREEQERFIFTVTAR 545
L +SATD DSG NA+I Y LGP+A F LDR+TG+LT + DRE++++++FT+ A+
Sbjct: 505 QLMKVSATDADSGPNAEINYLLGPDAPPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAK 564
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
DNG PPL S V V+++D+NDNSP FTHN ++F+V ENLP++ TVG+ITVTD D G+N
Sbjct: 565 DNGVPPLTSNVTVFVSIIDQNDNSPVFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNS 624
Query: 606 AVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINV 665
AVTLSIL++ND+F +D +GVI+ N+SFDRE+Q SYTF VKA DGG+ RSS+AKVTINV
Sbjct: 625 AVTLSILDENDDFTIDSQTGVIRPNISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINV 684
Query: 666 MDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGL 725
+DVNDN PV I PP N S++LV S PG+VV +V AVD DTGMNAE++Y+IV GN + L
Sbjct: 685 VDVNDNKPVFIVPPYNYSYELVLPSTNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDL 744
Query: 726 FRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIY 785
F ID TGNITL EK TD+GLHR++V +DLG P SL ++V+V L+VN++ NA+ I
Sbjct: 745 FAIDQETGNITLMEKCDVTDLGLHRVLVKANDLGQPDSLFSVVIVNLFVNESVTNATLIN 804
Query: 786 DLIRRTMETPLDRN--IGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASR 843
+L+R+++E P+ N I D S P DY+ I++A +AG + V+VVIF+T +VRCR A
Sbjct: 805 ELVRKSIEAPVTPNTEIADVSSP--TSDYVKILVAAVAGTITVVVVIFITAVVRCRQAPH 862
Query: 844 FKAAQRSKQGAEWMSPNQENKQ---NKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPI 900
KAAQ++ Q +EW +PN EN+Q KKKK+KK+ SPK+ LLN VTIEE+K DD +
Sbjct: 863 LKAAQKNMQNSEWATPNPENRQMIMMKKKKKKKKHSPKNLLLNVVTIEETKADDVDSDGN 922
Query: 901 NGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKK 960
T+ LP +LEEQ++G+++W PTTFKP+SPDLA+HYKSASPQPAF ++P+TP+++ K
Sbjct: 923 RVTLDLPIDLEEQTMGKYNW-VTTPTTFKPDSPDLARHYKSASPQPAFQIQPETPLNL-K 980
Query: 961 HHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECS-SQGGFKTKGPLHTRQSQRR 1016
HH+IQELPLDNTFV CD++S SS+SSD +S S+C F+ +HTR + R
Sbjct: 981 HHIIQELPLDNTFV-ACDSISNCSSSSSDPYSVSDCGYPVTTFEVPVSVHTRPTDSR 1036
>gi|27754773 protocadherin 1 isoform 2 precursor [Homo sapiens]
Length = 1237
Score = 748 bits (1931), Expect = 0.0
Identities = 472/1165 (40%), Positives = 656/1165 (56%), Gaps = 86/1165 (7%)
Query: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
+L AL+ L A ++Y + EE P N IG++ D + +Y+L
Sbjct: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH--------LYKL- 92
Query: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVI---LPNDFFR 124
+ G AP ++V TG+IFTT IDRE L + + C E EV I + N R
Sbjct: 93 -EVG-APYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPR 150
Query: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
L++ +I V+D NDN P F SPVI ++IPENT I S FPIP A+D D G NGV YEL G
Sbjct: 151 LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAG 210
Query: 185 ---QSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
Q +FGL + E E EK PQLIV NLDRE+ D+Y + IKV+DGG+P ++S+A+L+VT
Sbjct: 211 PEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVT 269
Query: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
V D NDN P F+ E + EN+P+G SVIQ+ A D+D G+NAEI Y F Q +R
Sbjct: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFH-QAPEVVRR 328
Query: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNID 359
L L+ TGLITVQ +DRE+ + + +VLA D + P ARA V + V D+NDN P I+
Sbjct: 329 LLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIE 388
Query: 360 LRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDN 417
+R I ++ +G +SE T +AL+ VSD+D N V C + +VPF L+ +
Sbjct: 389 IRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
Query: 418 ------QYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ 471
+Y L+T++ LDYE K+++ +IVA DSG P L+ T ++V++ D NDN P+F Q
Sbjct: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQ 508
Query: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASR 528
V E++ ENN+ G + I+A+D DSG NA++VY L P + F + +TG +
Sbjct: 509 SVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKT 568
Query: 529 VFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKY 588
DRE++E + V A D G+P LQ A V+V VLD NDN PKF + + F V EN+P
Sbjct: 569 SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL 628
Query: 589 STVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT 648
S VG++TV D D GEN V LS+ DN +FV+ +G I S++SFDREQQS+YTF +KA
Sbjct: 629 SPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAV 688
Query: 649 DGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTG 708
DGG PPRS+ VTINV+D NDN+P I+ PSNTS KL+ G V++V A D D+G
Sbjct: 689 DGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSG 747
Query: 709 MNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLV 768
+NAEL Y+I GN GLF+I +G ITLE++ GLHRLVV +SD G P T
Sbjct: 748 VNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGT-A 806
Query: 769 LVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIV 828
LV LYVN+T N + + L+ +++TPLD +I + +++ I+ ++AG + V +
Sbjct: 807 LVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVAL 866
Query: 829 VIFVTVLVR-CRH---ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNF 884
+I + VLVR CR S ++A ++ + P+ + + K K KK KSPK
Sbjct: 867 LIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKP----- 921
Query: 885 VTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASP 944
V E + + + + + + A + I P + P SPDL +HY+S SP
Sbjct: 922 VKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHL-------PLNYPPGSPDLGRHYRSNSP 974
Query: 945 QPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKT 1004
P+ L+P +P + KKH V+Q+LP NTFVG DT S S SD+ ++T
Sbjct: 975 LPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY----------SYRT 1024
Query: 1005 KGPLHTRQS--QRRVTF-------HLPDGSQESCSDSGLGDHEPVGSGTLISHPL-PLVQ 1054
P + + RRVTF L D SQ S DSGL + E S + L PL
Sbjct: 1025 NPPKYPSKQLPHRRVTFSATSQAQELQDPSQHSYYDSGLEESETPSSKSSSGPRLGPLAL 1084
Query: 1055 PQDEFYDQASPDKRTEADGN----SDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWM 1110
P+D + +RT DG+ P +D L P T CT+EC GHSD CWM
Sbjct: 1085 PEDHY-------ERTTPDGSIGEMEHPEND--LRPLPDVAMTGTCTRECSEFGHSDTCWM 1135
Query: 1111 PPGLGPYQHPKS---PLSTFAPQKE 1132
P P + KS LSTF P ++
Sbjct: 1136 PGQSSPSRRTKSSALKLSTFVPYQD 1160
>gi|14589935 protocadherin 7 isoform c precursor [Homo sapiens]
Length = 1200
Score = 709 bits (1831), Expect = 0.0
Identities = 466/1240 (37%), Positives = 667/1240 (53%), Gaps = 96/1240 (7%)
Query: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
Query: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
Query: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYE 180
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD D G NG++ YE
Sbjct: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
Query: 181 LLN--------GQS--VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTP 230
LL G+S D P G + + D GGT
Sbjct: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDA-----SEGGGGTN 236
Query: 231 QKSSTAILQVTVSDVNDNRP---VFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEI 287
+++ ++ V+D D + +G E + EN+ GT ++QL A D D+G N +I
Sbjct: 237 PGGRSSVFELQVADTPDGEKQPQLIVKGVYEADLAENSAPGTPILQLRAADLDVGVNGQI 296
Query: 288 RYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVT 345
Y+FGA + +RL L+ T+G ++V +DREE + TV+A D P +ATV
Sbjct: 297 EYVFGA-ATESVRRLLRLDETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVV 355
Query: 346 INVTDVNDNPPNIDLRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI 403
+N+ D NDN P+I++R I I +G ++E V+T IAL+ VSD+D NG V C +
Sbjct: 356 LNIKDENDNVPSIEIRKIGRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTV 415
Query: 404 EREVPFHLKAVYDNQ-------YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVR 456
+VPF LK D + Y L TS+ LDYE T+EF+ IVA DSG PSL+ +
Sbjct: 416 VGDVPFQLKPASDTEGDQNKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLI 475
Query: 457 VKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFF 515
VK+ D NDNPP+F Q V+E+ ENN G + T+ ATD DSGKNA+I Y L + F
Sbjct: 476 VKVGDTNDNPPMFGQSVVEVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIF 535
Query: 516 DLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHN 575
+D +G + + V DRE+ +R+ F V A+D G P LQ VIV V D+NDN PKF +
Sbjct: 536 AIDPDSGDILVNTVLDREQTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQD 595
Query: 576 HFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDR 635
F F+V ENL S VG++TV DAD G N ++L I +N+ F ++ +G I S +SFDR
Sbjct: 596 VFTFYVKENLQPNSPVGMVTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDR 655
Query: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
E Q++YTF VKA DGG PPRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +
Sbjct: 656 EHQTTYTFRVKAVDGGDPPRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRT 714
Query: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
VVA V A D D G+NA+L Y+IV GN LF IDP +G ++L K GLHRLVV +
Sbjct: 715 VVATVLATDSDDGINADLNYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQV 774
Query: 756 SDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTI 815
+D G P S T LV ++VN++ NA+ I I R++ PL ++I ++ L+I
Sbjct: 775 NDSGQP-SQSTTTLVHVFVNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSI 833
Query: 816 MIAIIAGAMVVIVVIFVTVLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKR 874
+I ++AG M VI++I + V+ R CR ++ K ++ +P Q +K K KK KK
Sbjct: 834 VIGVVAGIMTVILIILIVVMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKN 893
Query: 875 KSPKSSLL-NFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSP 933
K K L + VT+E SKP+ ++ +N +S + S+GR+ P SP
Sbjct: 894 KKSKQPLYSSIVTVEASKPNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSP 943
Query: 934 DLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSA 993
DLA+HYKS+SP P L P +P + KKH +Q+LP NTFVG D + S SDH S
Sbjct: 944 DLARHYKSSSPLPTVQLHPQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSE 999
Query: 994 SECSSQGGFKTKGPLHTRQSQRRVTFHL-------PDGSQESCSDSGLGDHEPVGSGTLI 1046
C + + ++Q RRVTF + GS +SC DSGL + E S +
Sbjct: 1000 YSCQTNNKY-------SKQPFRRVTFSVVSQPQDPHQGSLQSCYDSGLEESETPSSKSSS 1052
Query: 1047 SHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSD 1106
L + ++ Y++ +PD + S P D L T CT+EC GHSD
Sbjct: 1053 GPRLGALPLPEDNYERTTPDGSVD----SRPLPDVAL--------TGKCTRECDEYGHSD 1100
Query: 1107 NCWMPPGLGPYQHPKSP-LSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDR---- 1161
+CWMP P + P LSTF P E ++KL NG A D NRN N +
Sbjct: 1101 SCWMPVRTSPERKKSQPKLSTFMPVDERGSQEKLANGEA---AIMGDRNRNLLNKKLTSS 1157
Query: 1162 -KQYGSNEGHFNNGSHMTDIPLANLKSYKQAGGATESPKE 1200
+ + + N ++ DIPL YK + T + +E
Sbjct: 1158 YETFSAASFSKNEEANPEDIPLTKTGEYKPSPVNTLTRRE 1197
>gi|27754771 protocadherin 1 isoform 1 precursor [Homo sapiens]
Length = 1060
Score = 698 bits (1801), Expect = 0.0
Identities = 420/1006 (41%), Positives = 589/1006 (58%), Gaps = 50/1006 (4%)
Query: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
+L AL+ L A ++Y + EE P N IG++ D + +Y+L
Sbjct: 42 MLLALLLLLAPSPGHATRVVYKVPEEQPPNTLIGSLAADYGFPDVGH--------LYKL- 92
Query: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVI---LPNDFFR 124
+ G AP ++V TG+IFTT IDRE L + + C E EV I + N R
Sbjct: 93 -EVG-APYLRVDGKTGDIFTTETSIDREGLRECQNQLPGDPCILEFEVSITDLVQNGSPR 150
Query: 125 LIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG 184
L++ +I V+D NDN P F SPVI ++IPENT I S FPIP A+D D G NGV YEL G
Sbjct: 151 LLEGQIEVQDINDNTPNFASPVITLAIPENTNIGSLFPIPLASDRDAGPNGVASYELQAG 210
Query: 185 ---QSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
Q +FGL + E E EK PQLIV NLDRE+ D+Y + IKV+DGG+P ++S+A+L+VT
Sbjct: 211 PEAQELFGLQVAEDQE-EKQPQLIVMGNLDRERWDSYDLTIKVQDGGSPPRASSALLRVT 269
Query: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
V D NDN P F+ E + EN+P+G SVIQ+ A D+D G+NAEI Y F Q +R
Sbjct: 270 VLDTNDNAPKFERPSYEAELSENSPIGHSVIQVKANDSDQGANAEIEYTFH-QAPEVVRR 328
Query: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNID 359
L L+ TGLITVQ +DRE+ + + +VLA D + P ARA V + V D+NDN P I+
Sbjct: 329 LLRLDRNTGLITVQGPVDREDLSTLRFSVLAKDRGTNPKSARAQVVVTVKDMNDNAPTIE 388
Query: 360 LRYI--ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDN 417
+R I ++ +G +SE T +AL+ VSD+D N V C + +VPF L+ +
Sbjct: 389 IRGIGLVTHQDGMANISEDVAEETAVALVQVSDRDEGENAAVTCVVAGDVPFQLRQASET 448
Query: 418 ------QYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQ 471
+Y L+T++ LDYE K+++ +IVA DSG P L+ T ++V++ D NDN P+F Q
Sbjct: 449 GSDSKKKYFLQTTTPLDYEKVKDYTIEIVAVDSGNPPLSSTNSLKVQVVDVNDNAPVFTQ 508
Query: 472 PVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNAS---FFDLDRKTGVLTASR 528
V E++ ENN+ G + I+A+D DSG NA++VY L P + F + +TG +
Sbjct: 509 SVTEVAFPENNKPGEVIAEITASDADSGSNAELVYSLEPEPAAKGLFTISPETGEIQVKT 568
Query: 529 VFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKY 588
DRE++E + V A D G+P LQ A V+V VLD NDN PKF + + F V EN+P
Sbjct: 569 SLDREQRESYELKVVAADRGSPSLQGTATVLVNVLDCNDNDPKFMLSGYNFSVMENMPAL 628
Query: 589 STVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKAT 648
S VG++TV D D GEN V LS+ DN +FV+ +G I S++SFDREQQS+YTF +KA
Sbjct: 629 SPVGMVTVIDGDKGENAQVQLSVEQDNGDFVIQNGTGTILSSLSFDREQQSTYTFQLKAV 688
Query: 649 DGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTG 708
DGG PPRS+ VTINV+D NDN+P I+ PSNTS KL+ G V++V A D D+G
Sbjct: 689 DGGVPPRSAYVGVTINVLDENDNAP-YITAPSNTSHKLLTPQTRLGETVSQVAAEDFDSG 747
Query: 709 MNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLV 768
+NAEL Y+I GN GLF+I +G ITLE++ GLHRLVV +SD G P T
Sbjct: 748 VNAELIYSIAGGNPYGLFQIGSHSGAITLEKEIERRHHGLHRLVVKVSDRGKPPRYGT-A 806
Query: 769 LVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIV 828
LV LYVN+T N + + L+ +++TPLD +I + +++ I+ ++AG + V +
Sbjct: 807 LVHLYVNETLANRTLLETLLGHSLDTPLDIDIAGDPEYERSKQRGNILFGVVAGVVAVAL 866
Query: 829 VIFVTVLVR-CRH---ASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLLNF 884
+I + VLVR CR S ++A ++ + P+ + + K K KK KSPK
Sbjct: 867 LIALAVLVRYCRQREAKSGYQAGKKETKDLYAPKPSGKASKGNKSKGKKSKSPKP----- 921
Query: 885 VTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASP 944
V E + + + + + + A + I P + P SPDL +HY+S SP
Sbjct: 922 VKPVEDEDEAGLQKSLKFNLMSDAPGDSPRIHL-------PLNYPPGSPDLGRHYRSNSP 974
Query: 945 QPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDH 990
P+ L+P +P + KKH V+Q+LP NTFVG DT S S SD+
Sbjct: 975 LPSIQLQPQSPSASKKHQVVQDLPPANTFVGTGDTTSTGSEQYSDY 1020
>gi|14589931 protocadherin 7 isoform a precursor [Homo sapiens]
Length = 1069
Score = 697 bits (1799), Expect = 0.0
Identities = 427/1078 (39%), Positives = 606/1078 (56%), Gaps = 98/1078 (9%)
Query: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
Query: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
Query: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD
Sbjct: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
Query: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185
P G NG + + G
Sbjct: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241
Query: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV
Sbjct: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301
Query: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L
Sbjct: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360
Query: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363
+ T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418
I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D +
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474
Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533
E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593
+ +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
+TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713
PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L
Sbjct: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
Query: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773
Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++
Sbjct: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838
Query: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833
VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I +
Sbjct: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
Query: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891
V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK
Sbjct: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958
Query: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951
P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L
Sbjct: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008
Query: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGFKTKGPLH 1009
P +P + KKH +Q+LP NTFVG D + S SDH S C + + + LH
Sbjct: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKYSKQMRLH 1062
>gi|14589933 protocadherin 7 isoform b precursor [Homo sapiens]
Length = 1072
Score = 694 bits (1792), Expect = 0.0
Identities = 425/1071 (39%), Positives = 603/1071 (56%), Gaps = 98/1071 (9%)
Query: 4 RDFYLLAALIACLRLDSAIAQELI-YTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
R + L L+ L L A A++L+ Y + EE P +V IGN+ DL I TG S +
Sbjct: 11 RGWCLGCCLLLPLSLSLAAAKQLLRYRLAEEGPADVRIGNVASDLGI-----VTG-SGEV 64
Query: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVIL--PN 120
+ L S + +K+ + TGE+ T+ RIDREKL +ENECF + EV ++
Sbjct: 65 TFSLES---GSEYLKIDNLTGELSTSERRIDREKLPQCQMIFDENECFLDFEVSVIGPSQ 121
Query: 121 DFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATD------------ 168
+ L + ++IV D NDN P FPSPV+ +++ EN + + + +P+ATD
Sbjct: 122 SWVDLFEGQVIVLDINDNTPTFPSPVLTLTVEENRPVGTLYLLPTATDRDFGRNGIERYE 181
Query: 169 -------------------------PDTGFNGV---------QHYELLNG---------Q 185
P G NG + + G
Sbjct: 182 LLQEPGGGGSGGESRRAGAADSAPYPGGGGNGASGGGSGGSKRRLDASEGGGGTNPGGRS 241
Query: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
SVF L + +TP+GEK PQLIV+ LDREQ+D+Y + ++V DGG P +SS AIL+V ++DV
Sbjct: 242 SVFELQVADTPDGEKQPQLIVKGALDREQRDSYELTLRVRDGGDPPRSSQAILRVLITDV 301
Query: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
NDN P F++ E + EN+ GT ++QL A D D+G N +I Y+FGA + +RL L
Sbjct: 302 NDNSPRFEKSVYEADLAENSAPGTPILQLRAADLDVGVNGQIEYVFGA-ATESVRRLLRL 360
Query: 306 NNTTGLITVQRSLDREETAIHKVTVLASDGSSTPA--RATVTINVTDVNDNPPNIDLRYI 363
+ T+G ++V +DREE + TV+A D P +ATV +N+ D NDN P+I++R I
Sbjct: 361 DETSGWLSVLHRIDREEVNQLRFTVMARDRGQPPKTDKATVVLNIKDENDNVPSIEIRKI 420
Query: 364 --ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQ--- 418
I +G ++E V+T IAL+ VSD+D NG V C + +VPF LK D +
Sbjct: 421 GRIPLKDGVANVAEDVLVDTPIALVQVSDRDQGENGVVTCTVVGDVPFQLKPASDTEGDQ 480
Query: 419 ----YLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVI 474
Y L TS+ LDYE T+EF+ IVA DSG PSL+ + VK+ D NDNPP+F Q V+
Sbjct: 481 NKKKYFLHTSTPLDYEATREFNVVIVAVDSGSPSLSSNNSLIVKVGDTNDNPPMFGQSVV 540
Query: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFDLDRKTGVLTASRVFDRE 533
E+ ENN G + T+ ATD DSGKNA+I Y L + F +D +G + + V DRE
Sbjct: 541 EVYFPENNIPGERVATVLATDADSGKNAEIAYSLDSSVMGIFAIDPDSGDILVNTVLDRE 600
Query: 534 EQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGV 593
+ +R+ F V A+D G P LQ VIV V D+NDN PKF + F F+V ENL S VG+
Sbjct: 601 QTDRYEFKVNAKDKGIPVLQGSTTVIVQVADKNDNDPKFMQDVFTFYVKENLQPNSPVGM 660
Query: 594 ITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
+TV DAD G N ++L I +N+ F ++ +G I S +SFDRE Q++YTF VKA DGG P
Sbjct: 661 VTVMDADKGRNAEMSLYIEENNNIFSIENDTGTIYSTMSFDREHQTTYTFRVKAVDGGDP 720
Query: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAEL 713
PRS+TA V++ VMD NDN+P V + P N S+ L+P S+ +VVA V A D D G+NA+L
Sbjct: 721 PRSATATVSLFVMDENDNAPTV-TLPKNISYTLLPPSSNVRTVVATVLATDSDDGINADL 779
Query: 714 KYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLY 773
Y+IV GN LF IDP +G ++L K GLHRLVV ++D G P S T LV ++
Sbjct: 780 NYSIVGGNPFKLFEIDPTSGVVSLVGKLTQKHYGLHRLVVQVNDSGQP-SQSTTTLVHVF 838
Query: 774 VNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVT 833
VN++ NA+ I I R++ PL ++I ++ L+I+I ++AG M VI++I +
Sbjct: 839 VNESVSNATAIDSQIARSLHIPLTQDIAGDPSYEISKQRLSIVIGVVAGIMTVILIILIV 898
Query: 834 VLVR-CRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKKRKSPKSSLL-NFVTIEESK 891
V+ R CR ++ K ++ +P Q +K K KK KK K K L + VT+E SK
Sbjct: 899 VMARYCRSKNKNGYEAGKKDHEDFFTPQQHDKSKKPKKDKKNKKSKQPLYSSIVTVEASK 958
Query: 892 PDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTTFKPNSPDLAKHYKSASPQPAFHLK 951
P+ ++ +N +S + S+GR+ P SPDLA+HYKS+SP P L
Sbjct: 959 PNGQRYDSVNEKLS-----DSPSMGRY-----RSVNGGPGSPDLARHYKSSSPLPTVQLH 1008
Query: 952 PDTPVSVKKHHVIQELPLDNTFVGGCDTLSKRSSTSSDHFSASECSSQGGF 1002
P +P + KKH +Q+LP NTFVG D + S SDH S C + +
Sbjct: 1009 PQSPTAGKKHQAVQDLPPANTFVGAGDNI----SIGSDHCSEYSCQTNNKY 1055
>gi|190194360 protocadherin 20 [Homo sapiens]
Length = 951
Score = 656 bits (1692), Expect = 0.0
Identities = 364/823 (44%), Positives = 507/823 (61%), Gaps = 36/823 (4%)
Query: 6 FYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNI-----------SHINA 54
F+L +CL S A EL+Y++ E LP V IG++ +DL + S +
Sbjct: 49 FFLFVGPFSCLGSYSR-ATELLYSLNEGLPAGVLIGSLAEDLRLLPRSAGRPDPQSQLPE 107
Query: 55 ATGT--SASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCA------------G 100
TG + L + L S+ V + + +GE+ T++ IDRE LC
Sbjct: 108 RTGAEWNPPLSFSLASRGLSGQYVTLDNRSGELHTSAQEIDREALCVEGGGGTAWSGSVS 167
Query: 101 ASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSR 160
S + + C L+V++LP ++FR +K+KI ++D NDNAP FP I++ +PEN +N+R
Sbjct: 168 ISSSPSDSCLLLLDVLVLPQEYFRFVKVKIAIRDINDNAPQFPVSQISVWVPENAPVNTR 227
Query: 161 FPIPS-ATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYV 219
I A DPD G NGVQ Y LL+ +F LD+ E GE+ P LIV LDRE +D YV
Sbjct: 228 LAIEHPAVDPDVGINGVQTYRLLDYHGMFTLDVEENENGERTPYLIVMGALDRETQDQYV 287
Query: 220 MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDA 279
I EDGG+P +A L + +SD+NDN P+F + Q+ V + NA VGT + + A D
Sbjct: 288 SIIIAEDGGSPPLLGSATLTIGISDINDNCPLFTDSQINVTVYGNATVGTPIAAVQAVDK 347
Query: 280 DIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP 339
D+G+NA+I Y + +V A+K LF L+ TG+I + + HK+T+LA+ P
Sbjct: 348 DLGTNAQITYSYSQKVPQASKDLFHLDENTGVIKLFSKIGGSVLESHKLTILANGPGCIP 407
Query: 340 ARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKV 399
A T +++ V PP I RYI + I+G VYL E +PVNT IA T+ +D + KV
Sbjct: 408 AVITALVSIIKVIFRPPEIVPRYIANEIDGVVYLKELEPVNTPIAFFTI--RDPEGKYKV 465
Query: 400 ICFIEREVPFHLKAV--YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRV 457
C+++ E PF L Y+N+YLLET+ +DYE + + +VA +S + +++V
Sbjct: 466 NCYLDGEGPFRLSPYKPYNNEYLLETTKPMDYELQQFYEVAVVAWNS--EGFHVKRVIKV 523
Query: 458 KLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNA-SFFD 516
+L D+NDN PIF QP+IEL++ ENN +LT + ATD DS + + Y LGP+A S+F
Sbjct: 524 QLLDDNDNAPIFLQPLIELTIEENNSPNAFLTKLYATDADSEERGQVSYFLGPDAPSYFS 583
Query: 517 LDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNH 576
LD TG+LT S DREE+E++ +TV A D G PP +S A V +TVLD+NDNSP+F +
Sbjct: 584 LDSVTGILTVSTQLDREEKEKYRYTVRAVDCGKPPRESVATVALTVLDKNDNSPRFINKD 643
Query: 577 FQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSGVIKSNVSFDRE 636
F FFV EN P Y +GVI+VTDADAG N V LS++N +D FV+D G++++ VS DRE
Sbjct: 644 FSFFVPENFPGYGEIGVISVTDADAGRNGWVALSVVNQSDIFVIDTGKGMLRAKVSLDRE 703
Query: 637 QQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSV 696
QQSSYT V+A DGG+P SSTAK+TI ++D+NDN P+V+ P SN S+ LV S +PGS
Sbjct: 704 QQSSYTLWVEAVDGGEPALSSTAKITILLLDINDNPPLVLFPQSNMSYLLVLPSTLPGSP 763
Query: 697 VAEVFAVDVDTGMNAELKYTIVS--GNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVN 754
V EV+AVD DTGMNA + Y+I+ G FRIDP TGNITLEE TD GLHRL+V
Sbjct: 764 VTEVYAVDKDTGMNAVIAYSIIGRRGPRPESFRIDPKTGNITLEEALLQTDYGLHRLLVK 823
Query: 755 ISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLD 797
+SD GYP+ LH+ V+V L+VNDT N SYI L+R+ E ++
Sbjct: 824 VSDHGYPEPLHSTVMVNLFVNDTVSNESYIESLLRKEPEINIE 866
>gi|14589929 protocadherin 18 precursor [Homo sapiens]
Length = 1135
Score = 383 bits (984), Expect = e-106
Identities = 224/664 (33%), Positives = 362/664 (54%), Gaps = 28/664 (4%)
Query: 7 YLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL 66
++ A LI D + + L Y I EE I + +D ++ + +++ +R
Sbjct: 12 FVFALLIVSFNHD-VLGKNLKYRIYEEQRVGSVIARLSED--VADVLLKLPNPSTVRFRA 68
Query: 67 VSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLI 126
+ + G++PL+ V+ GEI + IDRE+LC + C E +V+ LP + +L
Sbjct: 69 MQR-GNSPLLVVNEDNGEI-SIGATIDREQLCQ-----KNLNCSIEFDVITLPTEHLQLF 121
Query: 127 KIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS 186
I++ V D NDN+P F +I I I E+ + +R P+ SA DPD G N + Y L +
Sbjct: 122 HIEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSL-SAND 180
Query: 187 VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVN 246
F +++ +G K+ +LIV + LDRE K +Y +++ D G PQ+S ++IL++++SD N
Sbjct: 181 FFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASDMGVPQRSGSSILKISISDSN 240
Query: 247 DNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALN 306
DN P F++ + + EN+PVGT ++ L+ATD D G+N +I Y F + V+P F ++
Sbjct: 241 DNSPAFEQQSYIIQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPKIMETFKID 300
Query: 307 NTTGLITVQRSLDREETAIHKVTVLASD--GSSTPARATVTINVTDVNDNPPNIDLRYII 364
+ G +T+ + +D E T +++ V A D +S PA + I V DVNDN P I++ +
Sbjct: 301 SERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKPEININLMS 360
Query: 365 SPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETS 424
Y+ E DP++T +AL+ V DKD+ +NG+++C + F L+ Y+N YL+ T+
Sbjct: 361 PGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYENNYLILTN 420
Query: 425 SLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRR 484
+ LD E E+S ++A D G PSL+ V++ D NDNPP F + E +SENN
Sbjct: 421 ATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEFVISENNSP 480
Query: 485 GLYLTTISATDEDSGKNADIVYQ------LGPN-ASFFDLDRKTGVLTASRVFDREEQER 537
G Y+TT++ATD D G+N + Y LG + ++ +D G + A R+FD EE +
Sbjct: 481 GAYITTVTATDPDLGENGQVTYTILESFILGSSITTYVTIDPSNGAIYALRIFDHEEVSQ 540
Query: 538 FIFTVTARDNGTP-PLQSQAAVIVTVLDENDN-----SPKFTHNHFQFFVSENLPKYSTV 591
F V ARD G+P L S V++T++DENDN P +N + + + V
Sbjct: 541 ITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEITIPKGAESGFHV 600
Query: 592 GVITVTDADAGENKAVTLSIL--NDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATD 649
I D D+G N ++ +I+ N+ + F++DP S I +NVS D + + V D
Sbjct: 601 TRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPYTEWELSVIIQD 660
Query: 650 GGQP 653
G P
Sbjct: 661 KGNP 664
Score = 273 bits (697), Expect = 9e-73
Identities = 264/968 (27%), Positives = 417/968 (43%), Gaps = 139/968 (14%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
++V V D+NDN P F + + I E+A VGT + A D D+G N+ Y A
Sbjct: 123 IEVEVLDINDNSPQFSRSLIPIEISESAAVGTRIPLDSAFDPDVGENSLHTYSLSAN--- 179
Query: 298 ATKRLFALNNTTGL----ITVQRSLDREETAIHKVTVLASDGSSTPARA---TVTINVTD 350
+ T G + V R LDRE + +++ + ASD P R+ + I+++D
Sbjct: 180 DFFNIEVRTRTDGAKYAELIVVRELDRELKSSYELQLTASD-MGVPQRSGSSILKISISD 238
Query: 351 VNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFH 410
NDN P + + I + L E PV T + + +D D NGK++ V
Sbjct: 239 SNDNSPAFEQQSYI------IQLLENSPVGTLLLDLNATDPDEGANGKIVYSFSSHVSPK 292
Query: 411 LKAVY---DNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPP 467
+ + + L +DYE TK + + A D G S+ + +K+ D NDN P
Sbjct: 293 IMETFKIDSERGHLTLFKQVDYEITKSYEIDVQAQDLGPNSIPAHCKIIIKVVDVNDNKP 352
Query: 468 IFNQPVI-----ELS-VSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFF--DLDR 519
N ++ E+S + E + ++ + D+DSG N +IV +L + F
Sbjct: 353 EININLMSPGKEEISYIFEGDPIDTFVALVRVQDKDSGLNGEIVCKLHGHGHFKLQKTYE 412
Query: 520 KTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQF 579
++ + DRE++ + TV A D GTP L + V + D NDN P F + ++F
Sbjct: 413 NNYLILTNATLDREKRSEYSLTVIAEDRGTPSLSTVKHFTVQINDINDNPPHFQRSRYEF 472
Query: 580 FVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVL----------DPYSGVIKS 629
+SEN + + +T TD D GEN VT +IL ++F+L DP +G I +
Sbjct: 473 VISENNSPGAYITTVTATDPDLGENGQVTYTIL---ESFILGSSITTYVTIDPSNGAIYA 529
Query: 630 NVSFDREQQSSYTFDVKATDGGQPPRS-STAKVTINVMDVNDNSPVVISPP--SNTSFKL 686
FD E+ S TF V+A DGG P + S V + ++D NDN PVVI P +NT+
Sbjct: 530 LRIFDHEEVSQITFVVEARDGGSPKQLVSNTTVVLTIIDENDNVPVVIGPALRNNTAEIT 589
Query: 687 VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDP----VTGNITLEEKPA 742
+P A G V + A+D D+G+NAEL IV+GN + +F IDP + N++++ P
Sbjct: 590 IPKGAESGFHVTRIRAIDRDSGVNAELSCAIVAGNEENIFIIDPRSCDIHTNVSMDSVPY 649
Query: 743 PTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGD 802
L V I D G P+ LHT VL+ + + A + + T T + + D
Sbjct: 650 TE----WELSVIIQDKGNPQ-LHTKVLLKCMIFEYA-------ESVTSTAMTSVSQASLD 697
Query: 803 SSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQE 862
S + I + I ++VI+V+F T RC + K + E
Sbjct: 698 VSM------IIIISLGAICAVLLVIMVLFAT---RCN--------REKKDTRSYNCRVAE 740
Query: 863 NKQNKKKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGP 922
+ KR R+ K + TI NGT LP +S P
Sbjct: 741 STYQHHPKRPSRQIHKGDITLVPTI-------------NGT--LPIRSHHRS------SP 779
Query: 923 APPTTFKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFVGGCDTLSK 982
+ +SP L + + H ++ V++ +HV + L+ L+
Sbjct: 780 S-------SSPTLERGQMGSRQSHNSHQSLNSLVTISSNHVPENFSLE---------LTH 823
Query: 983 RSSTSSDHFSASECSSQGGFKTKGPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHEPVGS 1042
+ QG ++ + + R + L D + S DSG GD E S
Sbjct: 824 ATPAVEQVSQLLSMLHQGQYQPRPSFRGNKYSRSYRYALQDMDKFSLKDSGRGDSEAGDS 883
Query: 1043 GTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPN-SDGPLGPRGLAEATEMCTQECLV 1101
D + SP R +G SD +DG + A +CT+EC V
Sbjct: 884 --------------DYDLGRDSPIDRLLGEGFSDLFLTDGRI-----PAAMRLCTEECRV 924
Query: 1102 LGHSDNCWMPPGLGPYQHPKSPLSTFAPQKEWVKKDKLVNGHTLTRAWKEDSNRNQFNDR 1161
LGHSD CWMPP P +S + F P +E+ + + + H ++ ++D+ ++
Sbjct: 925 LGHSDQCWMPPLPSPSSDYRS--NMFIPGEEFPTQPQQQHPH---QSLEDDAQPADSGEK 979
Query: 1162 KQYGSNEG 1169
K+ S G
Sbjct: 980 KKSFSTFG 987
>gi|11128041 protocadherin gamma subfamily A, 10 isoform 1 precursor
[Homo sapiens]
Length = 936
Score = 372 bits (955), Expect = e-102
Identities = 231/663 (34%), Positives = 355/663 (53%), Gaps = 42/663 (6%)
Query: 23 AQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSST 82
A+++ Y+I EEL + +GNI KDL + A A R+VS+ G L ++ +
Sbjct: 32 ARQISYSIPEELEKGSFVGNISKDLGL-----APRELAERGVRIVSR-GRTQLFSLNPRS 85
Query: 83 GEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMF 142
G + T + RIDRE+LCA ++ C +++ D +L I+I V D NDNAP F
Sbjct: 86 GSLIT-AGRIDREELCAQSA-----RCVVSFNILV--EDRVKLFGIEIEVTDINDNAPKF 137
Query: 143 PSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWP 202
+ +++ I EN RFP+P A DPD G N +Q Y+L + F L + G K+P
Sbjct: 138 QAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSLRVQSRANGVKYP 196
Query: 203 QLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
+L+++ +LDRE++ + + + DGG P +S T ++ VTV D NDN PVF + V +P
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVP 256
Query: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRL-FALNNTTGLITVQRSLDRE 321
EN PVGT ++ + ATD D G+N E+ Y F + P T+ L F LN TG I + +LD E
Sbjct: 257 ENLPVGTQLLTVTATDRDEGANGEVTYSF--RKLPDTQLLKFQLNKYTGEIKISENLDYE 314
Query: 322 ETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNT 381
ET +++ + A DG + A A V I V DVNDN P + + + SP+ +E P+ T
Sbjct: 315 ETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV------TEDSPLGT 368
Query: 382 KIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVA 441
+AL+ V D D++ NG+V C I +PF L+ D+ Y L LD E ++ + A
Sbjct: 369 VVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTA 428
Query: 442 SDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKN 501
+D G P L+ A +++ D NDNPP F+Q + ENN RG + +++A D DS +N
Sbjct: 429 TDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKEN 488
Query: 502 ADIVYQLG-------PNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQS 554
A I+Y L P +S+ ++ TGVL A R FD E+ VTA D+G PPL S
Sbjct: 489 AQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSS 548
Query: 555 QAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------PKYSTVGVITVTDADAGENKA 606
++ + VLD+NDN+P+ + S + P Y V+ V D D+G+N
Sbjct: 549 NVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAV-DRDSGQNAW 607
Query: 607 VTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTIN 664
++ +L ++ F + ++G +++ + + V D GQPP S+T +T+
Sbjct: 608 LSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 667
Query: 665 VMD 667
V D
Sbjct: 668 VAD 670
Score = 246 bits (627), Expect = 1e-64
Identities = 189/636 (29%), Positives = 300/636 (47%), Gaps = 53/636 (8%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+++ V+D+NDN P F+ ++V I EN G A D D+G N+ Y Q++P
Sbjct: 123 IEIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSY----QLSP 178
Query: 298 ATKRLFAL---NNTTGL----ITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT- 349
+ F+L + G+ + ++ SLDREE AIH + + ASDG TV ++VT
Sbjct: 179 --NKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTV 236
Query: 350 -DVNDNPPNIDL-RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREV 407
D NDN P L Y +S + E PV T++ +T +D+D NG+V +
Sbjct: 237 FDANDNAPVFTLPEYRVS-------VPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLP 289
Query: 408 PFHLKAVYDNQYL--LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDN 465
L N+Y ++ S LDYE T + +I A D G + TA V + +ED NDN
Sbjct: 290 DTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDN 347
Query: 466 PPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGV-- 523
P + V+E++ G + ++ D DS +N + + F L++
Sbjct: 348 SPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF-KLEKSIDSYY 406
Query: 524 -LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVS 582
L R DRE+ + TVTA D G+PPL ++A ++ V D NDN P F+ + ++
Sbjct: 407 RLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIP 466
Query: 583 ENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFV-------LDPYSGVIKSNVSFDR 635
EN + +++ +T D D+ EN + S+ D V ++ +GV+ + SFD
Sbjct: 467 ENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDY 526
Query: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSA 691
EQ V A+D G PP SS +++ V+D NDN+P ++ P +T +L P SA
Sbjct: 527 EQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSA 586
Query: 692 IPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRL 751
PG +V +V AVD D+G NA L Y ++ + GLF + TG + D L
Sbjct: 587 EPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSL 646
Query: 752 VVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNED 811
VV + D G P T+ L + + DL + E+P + D +
Sbjct: 647 VVAVQDHGQPPLSATVTLTVAVADSI---PQVLADL--GSFESPANSETSDLTL------ 695
Query: 812 YLTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAA 847
YL + +A ++ + V++ + +R H SR A
Sbjct: 696 YLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQA 731
>gi|14196448 protocadherin gamma subfamily A, 10 isoform 2 precursor
[Homo sapiens]
Length = 850
Score = 372 bits (955), Expect = e-102
Identities = 231/663 (34%), Positives = 355/663 (53%), Gaps = 42/663 (6%)
Query: 23 AQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSST 82
A+++ Y+I EEL + +GNI KDL + A A R+VS+ G L ++ +
Sbjct: 32 ARQISYSIPEELEKGSFVGNISKDLGL-----APRELAERGVRIVSR-GRTQLFSLNPRS 85
Query: 83 GEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMF 142
G + T + RIDRE+LCA ++ C +++ D +L I+I V D NDNAP F
Sbjct: 86 GSLIT-AGRIDREELCAQSA-----RCVVSFNILV--EDRVKLFGIEIEVTDINDNAPKF 137
Query: 143 PSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWP 202
+ +++ I EN RFP+P A DPD G N +Q Y+L + F L + G K+P
Sbjct: 138 QAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSYQLSPNKH-FSLRVQSRANGVKYP 196
Query: 203 QLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
+L+++ +LDRE++ + + + DGG P +S T ++ VTV D NDN PVF + V +P
Sbjct: 197 ELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTVFDANDNAPVFTLPEYRVSVP 256
Query: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRL-FALNNTTGLITVQRSLDRE 321
EN PVGT ++ + ATD D G+N E+ Y F + P T+ L F LN TG I + +LD E
Sbjct: 257 ENLPVGTQLLTVTATDRDEGANGEVTYSF--RKLPDTQLLKFQLNKYTGEIKISENLDYE 314
Query: 322 ETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNT 381
ET +++ + A DG + A A V I V DVNDN P + + + SP+ +E P+ T
Sbjct: 315 ETGFYEIEIQAEDGGAYLATAKVLITVEDVNDNSPELTITSLFSPV------TEDSPLGT 368
Query: 382 KIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVA 441
+AL+ V D D++ NG+V C I +PF L+ D+ Y L LD E ++ + A
Sbjct: 369 VVALLNVHDLDSEQNGQVTCSILAYLPFKLEKSIDSYYRLVIHRALDREQVSSYNITVTA 428
Query: 442 SDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKN 501
+D G P L+ A +++ D NDNPP F+Q + ENN RG + +++A D DS +N
Sbjct: 429 TDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIPENNARGASIFSVTALDPDSKEN 488
Query: 502 ADIVYQLG-------PNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQS 554
A I+Y L P +S+ ++ TGVL A R FD E+ VTA D+G PPL S
Sbjct: 489 AQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDYEQFHELQMQVTASDSGDPPLSS 548
Query: 555 QAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------PKYSTVGVITVTDADAGENKA 606
++ + VLD+NDN+P+ + S + P Y V+ V D D+G+N
Sbjct: 549 NVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAV-DRDSGQNAW 607
Query: 607 VTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTIN 664
++ +L ++ F + ++G +++ + + V D GQPP S+T +T+
Sbjct: 608 LSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVA 667
Query: 665 VMD 667
V D
Sbjct: 668 VAD 670
Score = 246 bits (627), Expect = 1e-64
Identities = 189/636 (29%), Positives = 300/636 (47%), Gaps = 53/636 (8%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+++ V+D+NDN P F+ ++V I EN G A D D+G N+ Y Q++P
Sbjct: 123 IEIEVTDINDNAPKFQAENLDVKINENVAAGMRFPLPEAIDPDVGVNSLQSY----QLSP 178
Query: 298 ATKRLFAL---NNTTGL----ITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT- 349
+ F+L + G+ + ++ SLDREE AIH + + ASDG TV ++VT
Sbjct: 179 --NKHFSLRVQSRANGVKYPELVLEHSLDREEEAIHHLVLTASDGGDPLRSGTVLVSVTV 236
Query: 350 -DVNDNPPNIDL-RYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREV 407
D NDN P L Y +S + E PV T++ +T +D+D NG+V +
Sbjct: 237 FDANDNAPVFTLPEYRVS-------VPENLPVGTQLLTVTATDRDEGANGEVTYSFRKLP 289
Query: 408 PFHLKAVYDNQYL--LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDN 465
L N+Y ++ S LDYE T + +I A D G + TA V + +ED NDN
Sbjct: 290 DTQLLKFQLNKYTGEIKISENLDYEETGFYEIEIQAEDGG--AYLATAKVLITVEDVNDN 347
Query: 466 PPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGV-- 523
P + V+E++ G + ++ D DS +N + + F L++
Sbjct: 348 SPELTITSLFSPVTEDSPLGTVVALLNVHDLDSEQNGQVTCSILAYLPF-KLEKSIDSYY 406
Query: 524 -LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVS 582
L R DRE+ + TVTA D G+PPL ++A ++ V D NDN P F+ + ++
Sbjct: 407 RLVIHRALDREQVSSYNITVTATDGGSPPLSTEAHFMLQVADINDNPPTFSQVSYFTYIP 466
Query: 583 ENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFV-------LDPYSGVIKSNVSFDR 635
EN + +++ +T D D+ EN + S+ D V ++ +GV+ + SFD
Sbjct: 467 ENNARGASIFSVTALDPDSKENAQIIYSLAEDTIQGVPLSSYISINSDTGVLYALRSFDY 526
Query: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSA 691
EQ V A+D G PP SS +++ V+D NDN+P ++ P +T +L P SA
Sbjct: 527 EQFHELQMQVTASDSGDPPLSSNVSLSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSA 586
Query: 692 IPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRL 751
PG +V +V AVD D+G NA L Y ++ + GLF + TG + D L
Sbjct: 587 EPGYLVTKVVAVDRDSGQNAWLSYRLLKASEPGLFAVGEHTGEVRTARALLDRDALKQSL 646
Query: 752 VVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNED 811
VV + D G P T+ L + + DL + E+P + D +
Sbjct: 647 VVAVQDHGQPPLSATVTLTVAVADSI---PQVLADL--GSFESPANSETSDLTL------ 695
Query: 812 YLTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAA 847
YL + +A ++ + V++ + +R H SR A
Sbjct: 696 YLVVAVAAVSCVFLAFVIVLLAHRLRRWHKSRLLQA 731
>gi|94538350 protocadherin 17 precursor [Homo sapiens]
Length = 1159
Score = 370 bits (950), Expect = e-102
Identities = 252/679 (37%), Positives = 364/679 (53%), Gaps = 55/679 (8%)
Query: 24 QELIYTIREELPENVPIGNIPKDLNISH-----INAATGTSASLVYRLVSKAGDAP-LVK 77
+ L Y++ EE IGNI +D + G S S YR++ + AP L+
Sbjct: 19 KNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENS--APHLLD 76
Query: 78 VSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTND 137
V + +G ++T RIDRE LC +C LEV ND + IK+ ++D ND
Sbjct: 77 VDADSGLLYT-KQRIDRESLCR-----HNAKCQLSLEV--FANDK-EICMIKVEIQDIND 127
Query: 138 NAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELL-NGQSVFGLDIVETP 196
NAP F S I + I EN +RFP+ SA DPD G NG++ Y L + +FGLD+
Sbjct: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRDDHGLFGLDVKSRG 187
Query: 197 EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQ 256
+G K+P+L++Q+ LDREQ++ + + + DGG P +S+T + V V D NDN PVF+
Sbjct: 188 DGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSPVFEAPS 247
Query: 257 VEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQR 316
V +PENAP+GT VI L+ATDAD G N E+ Y F + V + LF+++ TGLI V+
Sbjct: 248 YLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSIDPKTGLIRVKG 307
Query: 317 SLDREETAIHKVTVLASD--GSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLS 374
+LD EE + ++ V A D + PA VT+ + D NDN P+I +S G LS
Sbjct: 308 NLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIG---FVSVRQGA--LS 362
Query: 375 EKDPVNTKIALITVSDKDTDVNGKVICFI---------------EREVPFHLKAVYDNQY 419
E P T IAL+ V+D+D+ NG++ C + VPF L+ YDN Y
Sbjct: 363 EAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEENYDNFY 422
Query: 420 LLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVS 479
+ T LD E E++ IVA D G P LN T +K+ DENDNPP F + + L V
Sbjct: 423 TVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLYVLQVH 482
Query: 480 ENNRRGLYLTTISATDEDSGKNADIVYQLGPN-------ASFFDLDRKTGVLTASRVFDR 532
ENN G YL ++ A D D G+N + Y + P+ ++ ++ G + A R F+
Sbjct: 483 ENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYALRSFNF 542
Query: 533 EEQERFIFTVTARDNGTPP-LQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE-NLPKYST 590
E+ + F F V A+D+G P L+S A V VTVLD NDN+P Q +E +P+ +
Sbjct: 543 EQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQVPRNAG 602
Query: 591 VGVITVT----DADAGENKAVTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFD 644
+G + T D+D GE+ +T I++ ND+ F +DP SG I++ F +
Sbjct: 603 LGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTPVVELV 662
Query: 645 VKATDGGQPPRSSTAKVTI 663
VK TD G+P S+ AK+ I
Sbjct: 663 VKVTDHGKPTLSAVAKLII 681
Score = 272 bits (695), Expect = 2e-72
Identities = 282/1055 (26%), Positives = 427/1055 (40%), Gaps = 149/1055 (14%)
Query: 139 APMFPSPVINISIPEN----TLINS-------RFPIPSATDPDTGFNGVQHYELLNGQSV 187
AP +N S+PE T+I + + +P A G + Y +L +
Sbjct: 13 APALTLKNLNYSVPEEQGAGTVIGNIGRDARLQPGLPPAERGGGGRSKSGSYRVLENSAP 72
Query: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND 247
LD V+ G L +Q +DRE + K ++ +++V + D+ND
Sbjct: 73 HLLD-VDADSG----LLYTKQRIDRESLCRHNAKCQLSLEVFANDKEICMIKVEIQDIND 127
Query: 248 NRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNN 307
N P F Q+E+ I ENA GT A D D G N Y+ LF L+
Sbjct: 128 NAPSFSSDQIEMDISENAAPGTRFPLTSAHDPDAGENGLRTYLLTRD----DHGLFGLDV 183
Query: 308 TTG-------LITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNI 358
+ + +Q++LDRE+ H + + A DG P ATV INV D NDN P
Sbjct: 184 KSRGDGTKFPELVIQKALDREQQNHHTLVLTALDGGEPPRSATVQINVKVIDSNDNSP-- 241
Query: 359 DLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD-- 416
+ + V L E P+ T + + +D D NG+V+ VP ++ ++
Sbjct: 242 ----VFEAPSYLVELPENAPLGTVVIDLNATDADEGPNGEVLYSFSSYVPDRVRELFSID 297
Query: 417 -NQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFN-QPVI 474
L+ LDYE + A D G + V VKL D NDN P V
Sbjct: 298 PKTGLIRVKGNLDYEENGMLEIDVQARDLGPNPIPAHCKVTVKLIDRNDNAPSIGFVSVR 357
Query: 475 ELSVSENNRRGLYLTTISATDEDSGKNADIVYQL-------------GPNASF-FDLDRK 520
+ ++SE G + + TD DSGKN + ++ GP S F L+
Sbjct: 358 QGALSEAAPPGTVIALVRVTDRDSGKNGQLQCRVLGGGGTGGGGGLGGPGGSVPFKLEEN 417
Query: 521 TG---VLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHF 577
+ R DRE Q+ + T+ ARD G+PPL S + + +LDENDN P+FT +
Sbjct: 418 YDNFYTVVTDRPLDRETQDEYNVTIVARDGGSPPLNSTKSFAIKILDENDNPPRFTKGLY 477
Query: 578 QFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFV-------LDPYSGVIKSN 630
V EN +G + D D G+N V+ SIL + V ++P +G I +
Sbjct: 478 VLQVHENNIPGEYLGSVLAQDPDLGQNGTVSYSILPSHIGDVSIYTYVSVNPTNGAIYAL 537
Query: 631 VSFDREQQSSYTFDVKATDGGQPPR-SSTAKVTINVMDVNDNSPVVISPP--SNTSFKLV 687
SF+ EQ ++ F V A D G P S A V + V+DVNDN+PV++ P ++T+ V
Sbjct: 538 RSFNFEQTKAFEFKVLAKDSGAPAHLESNATVRVTVLDVNDNAPVIVLPTLQNDTAELQV 597
Query: 688 PLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVG 747
P +A G +V+ V A+D D G + L Y IV GN+ LF IDP +G I
Sbjct: 598 PRNAGLGYLVSTVRALDSDFGESGRLTYEIVDGNDDHLFEIDPSSGEIRTLHPFWEDVTP 657
Query: 748 LHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPY 807
+ LVV ++D G P S + LI R++ L + +
Sbjct: 658 VVELVVKVTDHGKP------------------TLSAVAKLIIRSVSGSLPEGVPRVNGEQ 699
Query: 808 QNEDYLTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQGAEWMSPNQENKQNK 867
+ D +I ++ ++++ +T+ V+C+ ++ + + + AE+ P + K
Sbjct: 700 HHWDMSLPLIVTLSTISIILLAAMITIAVKCKRENK-EIRTYNCRIAEYSHPQLGGGKGK 758
Query: 868 KKKRKKRKSPKSSLLNFVTIEESKPDDAVHEPINGTISLPAELEEQSIGRFDWGPAPPTT 927
KKK K N + + +E+EE++ A
Sbjct: 759 KKKINK---------------------------NDIMLVQSEVEERN--------AMNVM 783
Query: 928 FKPNSPDLAKHYKSASPQPAFHLKPDTPVSVKKHHVIQELPLDNTFV-----GGCDTLSK 982
+SP LA SP F + P+S + V+ P N GC T
Sbjct: 784 NVVSSPSLA-----TSPM-YFDYQTRLPLSSPRSEVMYLKPASNNLTVPQGHAGCHTSFT 837
Query: 983 RSSTSSDHFSASECS--SQGGFKTK-GPLHTRQSQRRVTFHLPDGSQESCSDSGLGDHEP 1039
T++ A+ S F + + +RQ + + D + S DSG GD +
Sbjct: 838 GQGTNASETPATRMSIIQTDNFPAEPNYMGSRQQFVQSSSTFKDPERASLRDSGHGDSDQ 897
Query: 1040 VGSGTLISHPLPLVQPQDEFYDQASPDKRTEADGNSDPNSDGPLGPRGLAEATEMCTQEC 1099
S D +A K T S P P E CT EC
Sbjct: 898 ADS----DQDTNKGSCCDMSVREALKMKTTST--KSQPLEQEP-------EECVNCTDEC 944
Query: 1100 LVLGHSDNCWMP--PGLGPYQHPKSPLSTFAPQKE 1132
VLGHSD CWMP P ++ + F P E
Sbjct: 945 RVLGHSDRCWMPQFPAANQAENADYRTNLFVPTVE 979
>gi|157426847 protocadherin 19 isoform a [Homo sapiens]
Length = 1101
Score = 370 bits (949), Expect = e-102
Identities = 246/710 (34%), Positives = 374/710 (52%), Gaps = 35/710 (4%)
Query: 12 LIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAG 71
L+A L +A L Y++ EE I N+ KD A + +R+VS +
Sbjct: 11 LLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAR--EAGFALDPRQASAFRVVSNS- 67
Query: 72 DAP-LVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKI 130
AP LV ++ S+G + T +IDR+ LC + +C LEV+ + + IK+
Sbjct: 68 -APHLVDINPSSG-LLVTKQKIDRDLLCR-----QSPKCIISLEVM---SSSMEICVIKV 117
Query: 131 IVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGL 190
+KD NDNAP FP+ I + I E +R P+ SA DPD+G GVQ YEL + +FGL
Sbjct: 118 EIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFGL 176
Query: 191 DIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRP 250
+I +G ++ +L+V+++LDRE + Y +I DGG P + T L + V+D NDN P
Sbjct: 177 EIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP 236
Query: 251 VFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTG 310
VF E V +PEN+P T VI+L+A+D D G+N ++ Y F V T+ LF ++ +G
Sbjct: 237 VFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSG 296
Query: 311 LITVQRSLDREETAIHKVTVLASD--GSSTPARATVTINVTDVNDNPPNIDLRYIISPIN 368
L+TV +LD EE ++++ V A D +S PA VT++V D NDNPP I+L + S +
Sbjct: 297 LVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSEL- 355
Query: 369 GTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLD 428
V +SE P IAL+ VSD+D+ +NG+V C + VPF L+ Y++ + LD
Sbjct: 356 --VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLD 412
Query: 429 YEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYL 488
E +++ I A D G P L V + DENDN P F++P ++ V ENN G YL
Sbjct: 413 REQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYL 472
Query: 489 TTISATDEDSGKNADIVYQLGPNA-------SFFDLDRKTGVLTASRVFDREEQERFIFT 541
++SA D D G N + YQ+ P+ ++ ++ +G + A R F+ E+ + F F
Sbjct: 473 LSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFK 532
Query: 542 VTARDNGTPPLQSQAAVIVTVLDENDNSPKFT-----HNHFQFFVSENLPKYSTVGVITV 596
V A+D G P LQS A V V +LD NDN+P T + + ++ N V V+
Sbjct: 533 VLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKA 592
Query: 597 TDADAGENKAVTLSIL-NDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPR 655
D D GEN VT + D F +D +G +++ +F +SSY V A D G+
Sbjct: 593 EDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSL 652
Query: 656 SSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDV 705
S++A V I + D + S + F ++ L +I G + + V +
Sbjct: 653 SASALVLIYLSPALDAQESMGSVNLSLIF-IIALGSIAGILFVTMIFVAI 701
Score = 242 bits (618), Expect = 1e-63
Identities = 198/697 (28%), Positives = 313/697 (44%), Gaps = 68/697 (9%)
Query: 204 LIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPE 263
L+ +Q +DR+ K + +++V + D+NDN P F Q+E+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 264 NAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPAT-KRLFALNNTT-------GLITVQ 315
A GT + A D D GS FG Q T LF L T + V+
Sbjct: 141 AASPGTRIPLDSAYDPDSGS-------FGVQTYELTPNELFGLEIKTRGDGSRFAELVVE 193
Query: 316 RSLDREETAIHKVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYL 373
+SLDRE + + + A DG P TV +I VTD NDN P + S V +
Sbjct: 194 KSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSV 247
Query: 374 SEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYE 430
E P NT + + SD D NG+V+ V + ++ + L+ + LDYE
Sbjct: 248 PENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYE 307
Query: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE---LSVSENNRRGLY 487
+ + A D G S+ V V + D NDNPP+ N + + VSE+ G
Sbjct: 308 EGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYV 367
Query: 488 LTTISATDEDSGKNADIVYQLGPNASFF--DLDRKTGVLTASRVFDREEQERFIFTVTAR 545
+ + +D DSG N + +L N F + + + +L R+ DRE+ +++ T+ AR
Sbjct: 368 IALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRL-DREQHDQYNLTIQAR 426
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
D G P LQS + V + DENDN P F+ ++Q V EN + + ++ D D G N
Sbjct: 427 DGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNG 486
Query: 606 AVTLSIL----NDNDNFV---LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSST 658
+V+ I+ D F ++P SG I + SF+ EQ ++ F V A DGG P S
Sbjct: 487 SVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSN 546
Query: 659 AKVTINVMDVNDNSPVVISPP--SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYT 716
A V + ++DVNDN+PV+ +PP + T+ +P ++ G +V V A D D G N + Y
Sbjct: 547 ATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYD 606
Query: 717 IVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVND 776
+ G+ +G F ID V G + + + L+V D G SL LV +Y++
Sbjct: 607 MTEGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHG-KTSLSASALVLIYLSP 664
Query: 777 TAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLV 836
D+ + + + I I + ++ V + V +
Sbjct: 665 AL-----------------------DAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAI 701
Query: 837 RCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKK 873
+C+ ++ + + + AE+ S + K +KKKK K
Sbjct: 702 KCKRDNK-EIRTYNCRIAEY-SYGHQKKSSKKKKISK 736
Score = 160 bits (406), Expect = 5e-39
Identities = 146/530 (27%), Positives = 224/530 (42%), Gaps = 34/530 (6%)
Query: 295 VAPATKRLFALNNTTGLITVQRSLDREETAIH--KVTVLASDGSSTPARATVTINVTDVN 352
V+ + L +N ++GL+ ++ +DR+ K + SS+ + + + D+N
Sbjct: 64 VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLN 123
Query: 353 DNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHL- 411
DN P+ I + +SE T+I L + D D+ G + F L
Sbjct: 124 DNAPSFPAAQI------ELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLE 177
Query: 412 -KAVYDNQYLLE--TSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPI 468
K D E LD E +SF+I A D G P T + +K+ D NDN P+
Sbjct: 178 IKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPV 237
Query: 469 FNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL-----GPNASFFDLDRKTGV 523
F++ +SV EN+ + ++A+D D G N +VY F +D +G+
Sbjct: 238 FSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGL 297
Query: 524 LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKF---THNHFQFF 580
+T + D EE + V A+D G + + V V+VLD NDN P + N
Sbjct: 298 VTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVE 357
Query: 581 VSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSG--VIKSNVSFDREQQ 638
VSE+ P + ++ V+D D+G N V +L N F L Y I + DREQ
Sbjct: 358 VSESAPPGYVIALVRVSDRDSGLNGRVQCRLLG-NVPFRLQEYESFSTILVDGRLDREQH 416
Query: 639 SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVA 698
Y ++A DGG P S T+ + D NDN P P +V + PG+ +
Sbjct: 417 DQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQV---IVQENNTPGAYLL 473
Query: 699 EVFAVDVDTGMNAELKYTIVSGNNKGL-----FRIDPVTGNITLEEKPAPTDVGLHRLVV 753
V A D D G+N + Y IV + + I+P +G+I V
Sbjct: 474 SVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKV 533
Query: 754 NISDLGYP--KSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIG 801
D G P +S T+ ++ L VND + LI T E + RN G
Sbjct: 534 LAKDGGLPSLQSNATVRVIILDVNDNTPVIT-APPLINGTAEVYIPRNSG 582
Score = 38.1 bits (87), Expect = 0.051
Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Query: 1095 CTQECLVLGHSDNCWMPPGLGPYQHPKSP 1123
C +EC +LGHSD CWMP P + KSP
Sbjct: 910 CREECRILGHSDRCWMPRNPMPIR-SKSP 937
>gi|157426845 protocadherin 19 isoform b [Homo sapiens]
Length = 1100
Score = 370 bits (949), Expect = e-102
Identities = 246/710 (34%), Positives = 374/710 (52%), Gaps = 35/710 (4%)
Query: 12 LIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAG 71
L+A L +A L Y++ EE I N+ KD A + +R+VS +
Sbjct: 11 LLAILWTQAAALINLKYSVEEEQRAGTVIANVAKDAR--EAGFALDPRQASAFRVVSNS- 67
Query: 72 DAP-LVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKI 130
AP LV ++ S+G + T +IDR+ LC + +C LEV+ + + IK+
Sbjct: 68 -APHLVDINPSSG-LLVTKQKIDRDLLCR-----QSPKCIISLEVM---SSSMEICVIKV 117
Query: 131 IVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGL 190
+KD NDNAP FP+ I + I E +R P+ SA DPD+G GVQ YEL + +FGL
Sbjct: 118 EIKDLNDNAPSFPAAQIELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNE-LFGL 176
Query: 191 DIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRP 250
+I +G ++ +L+V+++LDRE + Y +I DGG P + T L + V+D NDN P
Sbjct: 177 EIKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP 236
Query: 251 VFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTG 310
VF E V +PEN+P T VI+L+A+D D G+N ++ Y F V T+ LF ++ +G
Sbjct: 237 VFSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSG 296
Query: 311 LITVQRSLDREETAIHKVTVLASD--GSSTPARATVTINVTDVNDNPPNIDLRYIISPIN 368
L+TV +LD EE ++++ V A D +S PA VT++V D NDNPP I+L + S +
Sbjct: 297 LVTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSEL- 355
Query: 369 GTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLD 428
V +SE P IAL+ VSD+D+ +NG+V C + VPF L+ Y++ + LD
Sbjct: 356 --VEVSESAPPGYVIALVRVSDRDSGLNGRVQCRLLGNVPFRLQE-YESFSTILVDGRLD 412
Query: 429 YEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYL 488
E +++ I A D G P L V + DENDN P F++P ++ V ENN G YL
Sbjct: 413 REQHDQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYL 472
Query: 489 TTISATDEDSGKNADIVYQLGPNA-------SFFDLDRKTGVLTASRVFDREEQERFIFT 541
++SA D D G N + YQ+ P+ ++ ++ +G + A R F+ E+ + F F
Sbjct: 473 LSVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFK 532
Query: 542 VTARDNGTPPLQSQAAVIVTVLDENDNSPKFT-----HNHFQFFVSENLPKYSTVGVITV 596
V A+D G P LQS A V V +LD NDN+P T + + ++ N V V+
Sbjct: 533 VLAKDGGLPSLQSNATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKA 592
Query: 597 TDADAGENKAVTLSIL-NDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPR 655
D D GEN VT + D F +D +G +++ +F +SSY V A D G+
Sbjct: 593 EDYDEGENGRVTYDMTEGDRGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHGKTSL 652
Query: 656 SSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDV 705
S++A V I + D + S + F ++ L +I G + + V +
Sbjct: 653 SASALVLIYLSPALDAQESMGSVNLSLIF-IIALGSIAGILFVTMIFVAI 701
Score = 242 bits (618), Expect = 1e-63
Identities = 198/697 (28%), Positives = 313/697 (44%), Gaps = 68/697 (9%)
Query: 204 LIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPE 263
L+ +Q +DR+ K + +++V + D+NDN P F Q+E+ I E
Sbjct: 81 LVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLNDNAPSFPAAQIELEISE 140
Query: 264 NAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPAT-KRLFALNNTT-------GLITVQ 315
A GT + A D D GS FG Q T LF L T + V+
Sbjct: 141 AASPGTRIPLDSAYDPDSGS-------FGVQTYELTPNELFGLEIKTRGDGSRFAELVVE 193
Query: 316 RSLDREETAIHKVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYL 373
+SLDRE + + + A DG P TV +I VTD NDN P + S V +
Sbjct: 194 KSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNP------VFSESTYAVSV 247
Query: 374 SEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYE 430
E P NT + + SD D NG+V+ V + ++ + L+ + LDYE
Sbjct: 248 PENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGLVTVTGALDYE 307
Query: 431 GTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIE---LSVSENNRRGLY 487
+ + A D G S+ V V + D NDNPP+ N + + VSE+ G
Sbjct: 308 EGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVEVSESAPPGYV 367
Query: 488 LTTISATDEDSGKNADIVYQLGPNASFF--DLDRKTGVLTASRVFDREEQERFIFTVTAR 545
+ + +D DSG N + +L N F + + + +L R+ DRE+ +++ T+ AR
Sbjct: 368 IALVRVSDRDSGLNGRVQCRLLGNVPFRLQEYESFSTILVDGRL-DREQHDQYNLTIQAR 426
Query: 546 DNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENK 605
D G P LQS + V + DENDN P F+ ++Q V EN + + ++ D D G N
Sbjct: 427 DGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQVIVQENNTPGAYLLSVSARDPDLGLNG 486
Query: 606 AVTLSIL----NDNDNFV---LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSST 658
+V+ I+ D F ++P SG I + SF+ EQ ++ F V A DGG P S
Sbjct: 487 SVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKVLAKDGGLPSLQSN 546
Query: 659 AKVTINVMDVNDNSPVVISPP--SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYT 716
A V + ++DVNDN+PV+ +PP + T+ +P ++ G +V V A D D G N + Y
Sbjct: 547 ATVRVIILDVNDNTPVITAPPLINGTAEVYIPRNSGIGYLVTVVKAEDYDEGENGRVTYD 606
Query: 717 IVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVND 776
+ G+ +G F ID V G + + + L+V D G SL LV +Y++
Sbjct: 607 MTEGD-RGFFEIDQVNGEVRTTRTFGESSKSSYELIVVAHDHG-KTSLSASALVLIYLSP 664
Query: 777 TAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLV 836
D+ + + + I I + ++ V + V +
Sbjct: 665 AL-----------------------DAQESMGSVNLSLIFIIALGSIAGILFVTMIFVAI 701
Query: 837 RCRHASRFKAAQRSKQGAEWMSPNQENKQNKKKKRKK 873
+C+ ++ + + + AE+ S + K +KKKK K
Sbjct: 702 KCKRDNK-EIRTYNCRIAEY-SYGHQKKSSKKKKISK 736
Score = 160 bits (406), Expect = 5e-39
Identities = 146/530 (27%), Positives = 224/530 (42%), Gaps = 34/530 (6%)
Query: 295 VAPATKRLFALNNTTGLITVQRSLDREETAIH--KVTVLASDGSSTPARATVTINVTDVN 352
V+ + L +N ++GL+ ++ +DR+ K + SS+ + + + D+N
Sbjct: 64 VSNSAPHLVDINPSSGLLVTKQKIDRDLLCRQSPKCIISLEVMSSSMEICVIKVEIKDLN 123
Query: 353 DNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHL- 411
DN P+ I + +SE T+I L + D D+ G + F L
Sbjct: 124 DNAPSFPAAQI------ELEISEAASPGTRIPLDSAYDPDSGSFGVQTYELTPNELFGLE 177
Query: 412 -KAVYDNQYLLE--TSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPI 468
K D E LD E +SF+I A D G P T + +K+ D NDN P+
Sbjct: 178 IKTRGDGSRFAELVVEKSLDRETQSHYSFRITALDGGDPPRLGTVGLSIKVTDSNDNNPV 237
Query: 469 FNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL-----GPNASFFDLDRKTGV 523
F++ +SV EN+ + ++A+D D G N +VY F +D +G+
Sbjct: 238 FSESTYAVSVPENSPPNTPVIRLNASDPDEGTNGQVVYSFYGYVNDRTRELFQIDPHSGL 297
Query: 524 LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKF---THNHFQFF 580
+T + D EE + V A+D G + + V V+VLD NDN P + N
Sbjct: 298 VTVTGALDYEEGHVYELDVQAKDLGPNSIPAHCKVTVSVLDTNDNPPVINLLSVNSELVE 357
Query: 581 VSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFVLDPYSG--VIKSNVSFDREQQ 638
VSE+ P + ++ V+D D+G N V +L N F L Y I + DREQ
Sbjct: 358 VSESAPPGYVIALVRVSDRDSGLNGRVQCRLLG-NVPFRLQEYESFSTILVDGRLDREQH 416
Query: 639 SSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVA 698
Y ++A DGG P S T+ + D NDN P P +V + PG+ +
Sbjct: 417 DQYNLTIQARDGGVPMLQSAKSFTVLITDENDNHPHFSKPYYQV---IVQENNTPGAYLL 473
Query: 699 EVFAVDVDTGMNAELKYTIVSGNNKGL-----FRIDPVTGNITLEEKPAPTDVGLHRLVV 753
V A D D G+N + Y IV + + I+P +G+I V
Sbjct: 474 SVSARDPDLGLNGSVSYQIVPSQVRDMPVFTYVSINPNSGDIYALRSFNHEQTKAFEFKV 533
Query: 754 NISDLGYP--KSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIG 801
D G P +S T+ ++ L VND + LI T E + RN G
Sbjct: 534 LAKDGGLPSLQSNATVRVIILDVNDNTPVIT-APPLINGTAEVYIPRNSG 582
Score = 38.1 bits (87), Expect = 0.051
Identities = 16/29 (55%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Query: 1095 CTQECLVLGHSDNCWMPPGLGPYQHPKSP 1123
C +EC +LGHSD CWMP P + KSP
Sbjct: 909 CREECRILGHSDRCWMPRNPMPIR-SKSP 936
>gi|11056063 protocadherin gamma subfamily A, 7 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 367 bits (943), Expect = e-101
Identities = 235/683 (34%), Positives = 358/683 (52%), Gaps = 42/683 (6%)
Query: 2 DLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSAS 61
D R F+LL+ L+ A A ++Y++ EE + +G+I KDL + A
Sbjct: 9 DYRGFFLLSILLGTPW--EAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERG--- 63
Query: 62 LVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPND 121
R++S+ G L ++ +G + T+ RIDRE++CA ++ C IL D
Sbjct: 64 --VRIISR-GRTQLFALNQRSGSL-VTAGRIDREEICAQSA-----RCLVNFN--ILMED 112
Query: 122 FFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYEL 181
L I + + D NDN P F + IN+ I ENT RFP+ A DPD G N +Q Y+L
Sbjct: 113 KMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQL 172
Query: 182 LNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
+ F L + + K+P+L++++ LDRE++ + + + DGG P +SSTA +QVT
Sbjct: 173 SPNRH-FSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVT 231
Query: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
V DVND+ PVF Q +V +PEN PVGT ++ +HA D D G N E+ Y F ++ P +
Sbjct: 232 VVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSF-RKITPKLPK 290
Query: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLR 361
+F LN+ TG I+ LD EETA +++ V A DG + +A V I V DVNDN P + +
Sbjct: 291 MFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMT 350
Query: 362 YIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLL 421
+ S I E P+ T IAL + D+D+ NG+V C I +PF L+ DN Y L
Sbjct: 351 SLSSSI------PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRL 404
Query: 422 ETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSEN 481
T+ LD E ++ + A+D G P L++ + +++ D NDNPP F + ++EN
Sbjct: 405 VTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAEN 464
Query: 482 NRRGLYLTTISATDEDSGKNADIVYQL-------GPNASFFDLDRKTGVLTASRVFDREE 534
N RG + ++A D DS NA I Y L P +S+ ++ TGVL A + FD E+
Sbjct: 465 NPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQ 524
Query: 535 QERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------P 586
VTA D+G PPL S ++ + VLD+NDN P+ + S + P
Sbjct: 525 LRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEP 584
Query: 587 KYSTVGVITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFD 644
Y V+ V D D+G+N ++ +L ++ F + Y+G +++ + +
Sbjct: 585 GYLVTKVVAV-DKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 645 VKATDGGQPPRSSTAKVTINVMD 667
V D GQPP S+T +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 253 bits (647), Expect = 6e-67
Identities = 192/641 (29%), Positives = 301/641 (46%), Gaps = 53/641 (8%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+ V + D+NDN P F ++ V I EN G A D D+G+N+ Y Q++P
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSY----QLSP 174
Query: 298 ATKRLFALNNTTG-------LITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT- 349
R F+L +G + ++R LDREE +H + + ASDG P +T I VT
Sbjct: 175 --NRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 350 -DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP 408
DVND+ P + S V + E PV T++ + D D VNG+V + P
Sbjct: 233 VDVNDHTP------VFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITP 286
Query: 409 FHLKAVYDNQYLLETSSL--LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNP 466
K + N E S+L LDYE T + ++ A D G SL + A V + + D NDN
Sbjct: 287 KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQD-GPGSLTK-AKVLITVLDVNDNA 344
Query: 467 PIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFF---DLDRKTGV 523
P + S+ E+ G + D DSGKN ++ + N F +D +
Sbjct: 345 PEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRL 404
Query: 524 LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE 583
+T + DRE + T+ A D GTPPL + + + V D NDN P F H+ + +++E
Sbjct: 405 VTTKNL-DRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAE 463
Query: 584 NLPKYSTVGVITVTDADAGENKAVTLSILNDN------DNFV-LDPYSGVIKSNVSFDRE 636
N P+ +++ ++T D D+ +N +T S+ D ++V ++ +GV+ + SFD E
Sbjct: 464 NNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYE 523
Query: 637 QQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSAI 692
Q V A D G PP SS +++ V+D NDN P ++ P +T +L P SA
Sbjct: 524 QLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAE 583
Query: 693 PGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLV 752
PG +V +V AVD D+G NA L Y ++ + GLF + TG + D LV
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 753 VNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDY 812
V + D G P T+ L T A I +++ ++ S PY +
Sbjct: 644 VAVQDHGQPPLSATVTL-------TVAVADSIPEVLADL------GSLEPSDGPYNYDLT 690
Query: 813 LTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQG 853
L +++A+ + V + + V + +R R + + Q S+ G
Sbjct: 691 LYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGG 731
>gi|14196477 protocadherin gamma subfamily A, 7 isoform 2 precursor
[Homo sapiens]
Length = 817
Score = 367 bits (943), Expect = e-101
Identities = 235/683 (34%), Positives = 358/683 (52%), Gaps = 42/683 (6%)
Query: 2 DLRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSAS 61
D R F+LL+ L+ A A ++Y++ EE + +G+I KDL + A
Sbjct: 9 DYRGFFLLSILLGTPW--EAWAGRILYSVSEETDKGSFVGDIAKDLGLEPRELAERG--- 63
Query: 62 LVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPND 121
R++S+ G L ++ +G + T+ RIDRE++CA ++ C IL D
Sbjct: 64 --VRIISR-GRTQLFALNQRSGSL-VTAGRIDREEICAQSA-----RCLVNFN--ILMED 112
Query: 122 FFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYEL 181
L I + + D NDN P F + IN+ I ENT RFP+ A DPD G N +Q Y+L
Sbjct: 113 KMNLYPIDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSYQL 172
Query: 182 LNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVT 241
+ F L + + K+P+L++++ LDRE++ + + + DGG P +SSTA +QVT
Sbjct: 173 SPNRH-FSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVT 231
Query: 242 VSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKR 301
V DVND+ PVF Q +V +PEN PVGT ++ +HA D D G N E+ Y F ++ P +
Sbjct: 232 VVDVNDHTPVFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSF-RKITPKLPK 290
Query: 302 LFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLR 361
+F LN+ TG I+ LD EETA +++ V A DG + +A V I V DVNDN P + +
Sbjct: 291 MFHLNSLTGEISTLEGLDYEETAFYEMEVQAQDGPGSLTKAKVLITVLDVNDNAPEVTMT 350
Query: 362 YIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLL 421
+ S I E P+ T IAL + D+D+ NG+V C I +PF L+ DN Y L
Sbjct: 351 SLSSSI------PEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRL 404
Query: 422 ETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSEN 481
T+ LD E ++ + A+D G P L++ + +++ D NDNPP F + ++EN
Sbjct: 405 VTTKNLDRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAEN 464
Query: 482 NRRGLYLTTISATDEDSGKNADIVYQL-------GPNASFFDLDRKTGVLTASRVFDREE 534
N RG + ++A D DS NA I Y L P +S+ ++ TGVL A + FD E+
Sbjct: 465 NPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYEQ 524
Query: 535 QERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------P 586
VTA D+G PPL S ++ + VLD+NDN P+ + S + P
Sbjct: 525 LRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAEP 584
Query: 587 KYSTVGVITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFD 644
Y V+ V D D+G+N ++ +L ++ F + Y+G +++ + +
Sbjct: 585 GYLVTKVVAV-DKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 645 VKATDGGQPPRSSTAKVTINVMD 667
V D GQPP S+T +T+ V D
Sbjct: 644 VAVQDHGQPPLSATVTLTVAVAD 666
Score = 253 bits (647), Expect = 6e-67
Identities = 192/641 (29%), Positives = 301/641 (46%), Gaps = 53/641 (8%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+ V + D+NDN P F ++ V I EN G A D D+G+N+ Y Q++P
Sbjct: 119 IDVEIIDINDNVPRFLTEEINVKIMENTAPGVRFPLSEAGDPDVGTNSLQSY----QLSP 174
Query: 298 ATKRLFALNNTTG-------LITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT- 349
R F+L +G + ++R LDREE +H + + ASDG P +T I VT
Sbjct: 175 --NRHFSLAVQSGDDETKYPELVLERVLDREEERVHHLVLTASDGGDPPRSSTAHIQVTV 232
Query: 350 -DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP 408
DVND+ P + S V + E PV T++ + D D VNG+V + P
Sbjct: 233 VDVNDHTP------VFSLPQYQVTVPENVPVGTRLLTVHAIDLDEGVNGEVTYSFRKITP 286
Query: 409 FHLKAVYDNQYLLETSSL--LDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNP 466
K + N E S+L LDYE T + ++ A D G SL + A V + + D NDN
Sbjct: 287 KLPKMFHLNSLTGEISTLEGLDYEETAFYEMEVQAQD-GPGSLTK-AKVLITVLDVNDNA 344
Query: 467 PIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQLGPNASFF---DLDRKTGV 523
P + S+ E+ G + D DSGKN ++ + N F +D +
Sbjct: 345 PEVTMTSLSSSIPEDTPLGTVIALFYLQDRDSGKNGEVTCTIPENLPFKLEKSIDNYYRL 404
Query: 524 LTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSE 583
+T + DRE + T+ A D GTPPL + + + V D NDN P F H+ + +++E
Sbjct: 405 VTTKNL-DRETLSLYNITLKATDGGTPPLSRETHIFMQVADTNDNPPTFPHSSYSVYIAE 463
Query: 584 NLPKYSTVGVITVTDADAGENKAVTLSILNDN------DNFV-LDPYSGVIKSNVSFDRE 636
N P+ +++ ++T D D+ +N +T S+ D ++V ++ +GV+ + SFD E
Sbjct: 464 NNPRGASIFLVTAQDHDSEDNAQITYSLAEDTIQGAPVSSYVSINSDTGVLYALQSFDYE 523
Query: 637 QQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSAI 692
Q V A D G PP SS +++ V+D NDN P ++ P +T +L P SA
Sbjct: 524 QLRELQLRVTAHDSGDPPLSSNMSLSLFVLDQNDNPPEILYPALPTDGSTGMELAPRSAE 583
Query: 693 PGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLV 752
PG +V +V AVD D+G NA L Y ++ + GLF + TG + D LV
Sbjct: 584 PGYLVTKVVAVDKDSGQNAWLSYLLLKASEPGLFAVGLYTGEVRTARALLDRDALKQSLV 643
Query: 753 VNISDLGYPKSLHTLVLVFLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDY 812
V + D G P T+ L T A I +++ ++ S PY +
Sbjct: 644 VAVQDHGQPPLSATVTL-------TVAVADSIPEVLADL------GSLEPSDGPYNYDLT 690
Query: 813 LTIMIAIIAGAMVVIVVIFVTVLVRCRHASRFKAAQRSKQG 853
L +++A+ + V + + V + +R R + + Q S+ G
Sbjct: 691 LYLVVAVATVSCVFLAFVLVLLALRLRRWHKSRLLQASEGG 731
>gi|14589916 protocadherin 10 isoform 1 precursor [Homo sapiens]
Length = 1040
Score = 362 bits (929), Expect = 1e-99
Identities = 232/700 (33%), Positives = 367/700 (52%), Gaps = 61/700 (8%)
Query: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
++ L A L + + +L YT++EE +GNI +DL + T SA +
Sbjct: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLD----ITKLSARGFQTVP 57
Query: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIK 127
+ P + ++ TG ++ + +IDRE++C + C LEV + + L +
Sbjct: 58 NSR--TPYLDLNLETGVLYV-NEKIDREQICK-----QSPSCVLHLEVFL--ENPLELFQ 107
Query: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSV 187
++I V D NDN P FP P + + I E+ +RFP+ SA DPD G N ++ YE+ S
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-TPNSY 166
Query: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGG------------------- 228
F LD+ +G ++ +L++++ LDREQ+ + + DGG
Sbjct: 167 FSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPP 226
Query: 229 TPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIR 288
Q++ TA+L + V D NDN P F + V +PEN+P GT VIQL+ATD D G N E+
Sbjct: 227 QQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVV 286
Query: 289 YIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD--GSSTPARATVTI 346
Y F + ++P + LF L+ TG + V LD EE+ +++V V A D ++ PA V +
Sbjct: 287 YSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLV 346
Query: 347 NVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIERE 406
V D NDN P I + + SE T +AL +V+D+D++ NG+V C + +
Sbjct: 347 RVLDANDNAPEISFSTVKEAV------SEGAAPGTVVALFSVTDRDSEENGQVQCELLGD 400
Query: 407 VPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNP 466
VPF LK+ + N Y + T + LD E ++ +VA D G+P+L+ + ++V++ D NDN
Sbjct: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
Query: 467 PIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL------GPNA-SFFDLDR 519
P F+QPV ++ V+ENN G Y+ +SATD D G NA + Y + G + ++ ++
Sbjct: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
Query: 520 KTGVLTASRVFDREEQERFIFTVTARDNGTP-PLQSQAAVIVTVLDENDNSPKFT---HN 575
+ G L A R FD E+ + F F V ARD G+P L A V + ++D+NDN+P
Sbjct: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
Query: 576 HFQFFVSENLPKYSTVGV----ITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKS 629
E LP+ + G + DAD GEN +T SI+ N+ F +D +G +++
Sbjct: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
Query: 630 --NVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMD 667
V R+ Q Y ++ D GQPP SSTA + + ++D
Sbjct: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 226 bits (577), Expect = 8e-59
Identities = 190/661 (28%), Positives = 298/661 (45%), Gaps = 86/661 (13%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+++ V D+NDN P F E + V I E+A GT A D D+G+N+ Y ++ P
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDY----EITP 163
Query: 298 ATKRLFALN-------NTTGLITVQRSLDREETAIHKVTVLASDGSS------------- 337
+ F+L+ N + +++ LDRE+ A+H+ + A DG
Sbjct: 164 NS--YFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 338 --------TPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVS 389
A +TI V D NDN P D P+ TV L E P T + + +
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 390 DKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEGTKEFSFKIVASDSGK 446
D D NG+V+ + + ++ LE S LDYE + + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVY 506
++ V V++ D NDN P + ++ +VSE G + S TD DS +N +
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 507 QLGPNASFF--DLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLD 564
+L + F + + DRE + + TV ARD G P L + ++ V V D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 565 ENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFV----- 619
NDN+P+F+ + +V+EN + + ++ TD D G N + SIL +
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 620 --LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPR-SSTAKVTINVMDVNDNSPVVI 676
++ +G + + SFD EQ ++F V+A D G P + A V I ++D NDN+P ++
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 677 SP----PSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVT 732
+P + +++P SA PG ++ V AVD D G NA L Y+IV GN LFR+D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 733 GNI-TLEEKPAPTDVGL-HRLVVNISDLGYPKSLHTLVLVFLYVN---------DTAGNA 781
G + T PA D + LV+ + D G P T LV V+ + G
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGG 695
Query: 782 SYIYDLIRRT--METPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVL-VRC 838
S + R+ ET LD LT+++ I G++ I ++ + VL VRC
Sbjct: 696 SGEHQRPSRSGGGETSLD---------------LTLILIIALGSVSFIFLLAMIVLAVRC 740
Query: 839 R 839
+
Sbjct: 741 Q 741
Score = 39.3 bits (90), Expect = 0.023
Identities = 17/39 (43%), Positives = 23/39 (58%), Gaps = 1/39 (2%)
Query: 1073 GNSDPNSDGPLGPRGLAEATEMCTQECLVLGHSDNCWMP 1111
G+SD ++ G+ + CT+EC LGHSD CWMP
Sbjct: 919 GDSDHDATNRAQSAGM-DLFSNCTEECKALGHSDRCWMP 956
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 13/107 (12%)
Query: 660 KVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVS 719
+V I V+D+NDN P P + SA PG+ A D D G N+ Y I
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVE---ISESATPGTRFPLESAFDPDVGTNSLRDYEITP 163
Query: 720 GNNKGLFRIDPVT---GNITLE---EKPAPTD-VGLHRLVVNISDLG 759
+ F +D T GN E EKP + +HR V+ D G
Sbjct: 164 NS---YFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGG 207
>gi|14589914 protocadherin 10 isoform 2 precursor [Homo sapiens]
Length = 896
Score = 362 bits (929), Expect = 1e-99
Identities = 232/700 (33%), Positives = 367/700 (52%), Gaps = 61/700 (8%)
Query: 8 LLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLV 67
++ L A L + + +L YT++EE +GNI +DL + T SA +
Sbjct: 2 IVLLLFALLWMVEGVFSQLHYTVQEEQEHGTFVGNIAEDLGLD----ITKLSARGFQTVP 57
Query: 68 SKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIK 127
+ P + ++ TG ++ + +IDRE++C + C LEV + + L +
Sbjct: 58 NSR--TPYLDLNLETGVLYV-NEKIDREQICK-----QSPSCVLHLEVFL--ENPLELFQ 107
Query: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSV 187
++I V D NDN P FP P + + I E+ +RFP+ SA DPD G N ++ YE+ S
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDYEI-TPNSY 166
Query: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGG------------------- 228
F LD+ +G ++ +L++++ LDREQ+ + + DGG
Sbjct: 167 FSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGGAGLPP 226
Query: 229 TPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIR 288
Q++ TA+L + V D NDN P F + V +PEN+P GT VIQL+ATD D G N E+
Sbjct: 227 QQQRTGTALLTIRVLDSNDNVPAFDQPVYTVSLPENSPPGTLVIQLNATDPDEGQNGEVV 286
Query: 289 YIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD--GSSTPARATVTI 346
Y F + ++P + LF L+ TG + V LD EE+ +++V V A D ++ PA V +
Sbjct: 287 YSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGPNAVPAHCKVLV 346
Query: 347 NVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIERE 406
V D NDN P I + + SE T +AL +V+D+D++ NG+V C + +
Sbjct: 347 RVLDANDNAPEISFSTVKEAV------SEGAAPGTVVALFSVTDRDSEENGQVQCELLGD 400
Query: 407 VPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNP 466
VPF LK+ + N Y + T + LD E ++ +VA D G+P+L+ + ++V++ D NDN
Sbjct: 401 VPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSDVNDNA 460
Query: 467 PIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL------GPNA-SFFDLDR 519
P F+QPV ++ V+ENN G Y+ +SATD D G NA + Y + G + ++ ++
Sbjct: 461 PRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTYVSINS 520
Query: 520 KTGVLTASRVFDREEQERFIFTVTARDNGTP-PLQSQAAVIVTVLDENDNSPKFT---HN 575
+ G L A R FD E+ + F F V ARD G+P L A V + ++D+NDN+P
Sbjct: 521 ENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIVAPLPG 580
Query: 576 HFQFFVSENLPKYSTVGV----ITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKS 629
E LP+ + G + DAD GEN +T SI+ N+ F +D +G +++
Sbjct: 581 RNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRTGELRT 640
Query: 630 --NVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMD 667
V R+ Q Y ++ D GQPP SSTA + + ++D
Sbjct: 641 ARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVD 680
Score = 226 bits (577), Expect = 8e-59
Identities = 190/661 (28%), Positives = 298/661 (45%), Gaps = 86/661 (13%)
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+++ V D+NDN P F E + V I E+A GT A D D+G+N+ Y ++ P
Sbjct: 108 VEIEVLDINDNPPSFPEPDLTVEISESATPGTRFPLESAFDPDVGTNSLRDY----EITP 163
Query: 298 ATKRLFALN-------NTTGLITVQRSLDREETAIHKVTVLASDGSS------------- 337
+ F+L+ N + +++ LDRE+ A+H+ + A DG
Sbjct: 164 NS--YFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGGGGGGVGEGGGGGGG 221
Query: 338 --------TPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVS 389
A +TI V D NDN P D P+ TV L E P T + + +
Sbjct: 222 AGLPPQQQRTGTALLTIRVLDSNDNVPAFD-----QPVY-TVSLPENSPPGTLVIQLNAT 275
Query: 390 DKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEGTKEFSFKIVASDSGK 446
D D NG+V+ + + ++ LE S LDYE + + + A D G
Sbjct: 276 DPDEGQNGEVVYSFSSHISPRARELFGLSPRTGRLEVSGELDYEESPVYQVYVQAKDLGP 335
Query: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVY 506
++ V V++ D NDN P + ++ +VSE G + S TD DS +N +
Sbjct: 336 NAVPAHCKVLVRVLDANDNAPEISFSTVKEAVSEGAAPGTVVALFSVTDRDSEENGQVQC 395
Query: 507 QLGPNASFF--DLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLD 564
+L + F + + DRE + + TV ARD G P L + ++ V V D
Sbjct: 396 ELLGDVPFRLKSSFKNYYTIVTEAPLDREAGDSYTLTVVARDRGEPALSTSKSIQVQVSD 455
Query: 565 ENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDNFV----- 619
NDN+P+F+ + +V+EN + + ++ TD D G N + SIL +
Sbjct: 456 VNDNAPRFSQPVYDVYVTENNVPGAYIYAVSATDRDEGANAQLAYSILECQIQGMSVFTY 515
Query: 620 --LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPR-SSTAKVTINVMDVNDNSPVVI 676
++ +G + + SFD EQ ++F V+A D G P + A V I ++D NDN+P ++
Sbjct: 516 VSINSENGYLYALRSFDYEQLKDFSFQVEARDAGSPQALAGNATVNILIVDQNDNAPAIV 575
Query: 677 SP----PSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVT 732
+P + +++P SA PG ++ V AVD D G NA L Y+IV GN LFR+D T
Sbjct: 576 APLPGRNGTPAREVLPRSAEPGYLLTRVAAVDADDGENARLTYSIVRGNEMNLFRMDWRT 635
Query: 733 GNI-TLEEKPAPTDVGL-HRLVVNISDLGYPKSLHTLVLVFLYVN---------DTAGNA 781
G + T PA D + LV+ + D G P T LV V+ + G
Sbjct: 636 GELRTARRVPAKRDPQRPYELVIEVRDHGQPPLSSTATLVVQLVDGAVEPQGGGGSGGGG 695
Query: 782 SYIYDLIRRT--METPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVL-VRC 838
S + R+ ET LD LT+++ I G++ I ++ + VL VRC
Sbjct: 696 SGEHQRPSRSGGGETSLD---------------LTLILIIALGSVSFIFLLAMIVLAVRC 740
Query: 839 R 839
+
Sbjct: 741 Q 741
Score = 33.5 bits (75), Expect = 1.3
Identities = 34/107 (31%), Positives = 45/107 (42%), Gaps = 13/107 (12%)
Query: 660 KVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVS 719
+V I V+D+NDN P P + SA PG+ A D D G N+ Y I
Sbjct: 107 QVEIEVLDINDNPPSFPEPDLTVE---ISESATPGTRFPLESAFDPDVGTNSLRDYEITP 163
Query: 720 GNNKGLFRIDPVT---GNITLE---EKPAPTD-VGLHRLVVNISDLG 759
+ F +D T GN E EKP + +HR V+ D G
Sbjct: 164 NS---YFSLDVQTQGDGNRFAELVLEKPLDREQQAVHRYVLTAVDGG 207
>gi|8850232 protocadherin gamma subfamily A, 12 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 362 bits (928), Expect = 2e-99
Identities = 225/660 (34%), Positives = 352/660 (53%), Gaps = 40/660 (6%)
Query: 25 ELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGE 84
++ Y++ EEL + +G+I +DL + A R++ + G L ++ +G
Sbjct: 30 QIRYSVPEELEKGSRVGDISRDLGLEPRELAERG-----VRIIPR-GRTQLFALNPRSGS 83
Query: 85 IFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPS 144
+ T+ RIDRE+LC GA +C +L + IL D ++ +++ V+D NDNAP F
Sbjct: 84 L-VTAGRIDREELCMGAI-----KC--QLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135
Query: 145 PVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQL 204
+ I I EN RFP+P A DPD G N +Q YEL + + F L + +G K+P+L
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYEL-SPNTHFSLIVQNGADGSKYPEL 194
Query: 205 IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPEN 264
++++ LDRE+K + + + DGG P ++ TA ++V V D NDN P F + + +PEN
Sbjct: 195 VLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPEN 254
Query: 265 APVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETA 324
+GT ++ ++ATD D G NAE+RY F V ++F L+ +G I+ LD EE+
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 325 IHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIA 384
+++ V A D + ARA V I V DVNDN P + L + S + E P T IA
Sbjct: 314 FYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PENSPRGTLIA 367
Query: 385 LITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDS 444
L+ V+D+D++ NG+VICFI+ +PF L+ Y N Y L T +LD E ++ + A+D
Sbjct: 368 LLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDR 427
Query: 445 GKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADI 504
G P L+ + + + D NDNPP+F Q + ENN RG+ L +++A D D +NA I
Sbjct: 428 GTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQI 487
Query: 505 VYQLGPN-------ASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAA 557
Y L N +S+ ++ TGVL A FD E+ V ARDNG PPL S +
Sbjct: 488 TYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVS 547
Query: 558 VIVTVLDENDNSPKFTHNHFQFFVSENL--------PKYSTVGVITVTDADAGENKAVTL 609
+ + VLD+NDN+P+ + S + P Y V+ V D D+G+N ++
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAV-DRDSGQNAWLSY 606
Query: 610 SILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMD 667
+L ++ F + ++G +++ + + V D GQPP S+T +T+ V D
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Score = 244 bits (622), Expect = 5e-64
Identities = 195/670 (29%), Positives = 310/670 (46%), Gaps = 52/670 (7%)
Query: 204 LIVQQNLDREQKDTYVMKIKVE-DGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
L+ +DRE+ +K ++ D K ++V V D+NDN P F+E ++E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK-RLFALNNTTGL----ITVQRS 317
ENA HA D DIG N+ Y +++P T L N G + ++R+
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSY----ELSPNTHFSLIVQNGADGSKYPELVLKRA 199
Query: 318 LDREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNIDLRYIISPINGTVYLS 374
LDREE A H + + ASDG P R A + + V D NDN P + +
Sbjct: 200 LDREEKAAHHLVLTASDGGD-PVRTGTARIRVMVLDANDNAP------AFAQPEYRASVP 252
Query: 375 EKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEG 431
E + T++ ++ +D D VN +V + R V V+ N + T LD+E
Sbjct: 253 ENLALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEE 311
Query: 432 TKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTI 491
+ + ++ A D+ S L+ V D NDN P + SV EN+ RG + +
Sbjct: 312 SGFYQMEVQAMDNAGYSARAKVLITVL--DVNDNAPEVVLTSLASSVPENSPRGTLIALL 369
Query: 492 SATDEDSGKNADIVYQLGPNASFFDLDRKTG---VLTASRVFDREEQERFIFTVTARDNG 548
+ D+DS +N ++ + N F L++ G L V DRE+ + TVTA D G
Sbjct: 370 NVNDQDSEENGQVICFIQGNLPF-KLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRG 428
Query: 549 TPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVT 608
TPPL ++ + + V D NDN P F + ++ EN P+ ++ +T D D EN +T
Sbjct: 429 TPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQIT 488
Query: 609 LSILNDN------DNFV-LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKV 661
S+ + ++V ++ +GV+ + SFD EQ V A D G PP SS +
Sbjct: 489 YSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSL 548
Query: 662 TINVMDVNDNSPVVISPP----SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTI 717
++ V+D NDN+P ++ P +T +L P SA PG +V +V AVD D+G NA L Y +
Sbjct: 549 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 608
Query: 718 VSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDT 777
+ + GLF + TG + D LVV + D G P T+ L +
Sbjct: 609 LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 668
Query: 778 AGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVR 837
+ DL ++E+P + D + YL + +A ++ + V++ + + +R
Sbjct: 669 ---PQVLADL--GSLESPANSETSDLTL------YLVVAVAAVSCVFLAFVILLLALRLR 717
Query: 838 CRHASRFKAA 847
H SR A
Sbjct: 718 RWHKSRLLQA 727
>gi|14196457 protocadherin gamma subfamily A, 12 isoform 2 precursor
[Homo sapiens]
Length = 820
Score = 362 bits (928), Expect = 2e-99
Identities = 225/660 (34%), Positives = 352/660 (53%), Gaps = 40/660 (6%)
Query: 25 ELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGE 84
++ Y++ EEL + +G+I +DL + A R++ + G L ++ +G
Sbjct: 30 QIRYSVPEELEKGSRVGDISRDLGLEPRELAERG-----VRIIPR-GRTQLFALNPRSGS 83
Query: 85 IFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPS 144
+ T+ RIDRE+LC GA +C +L + IL D ++ +++ V+D NDNAP F
Sbjct: 84 L-VTAGRIDREELCMGAI-----KC--QLNLDILMEDKVKIYGVEVEVRDINDNAPYFRE 135
Query: 145 PVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQL 204
+ I I EN RFP+P A DPD G N +Q YEL + + F L + +G K+P+L
Sbjct: 136 SELEIKISENAATEMRFPLPHAWDPDIGKNSLQSYEL-SPNTHFSLIVQNGADGSKYPEL 194
Query: 205 IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPEN 264
++++ LDRE+K + + + DGG P ++ TA ++V V D NDN P F + + +PEN
Sbjct: 195 VLKRALDREEKAAHHLVLTASDGGDPVRTGTARIRVMVLDANDNAPAFAQPEYRASVPEN 254
Query: 265 APVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETA 324
+GT ++ ++ATD D G NAE+RY F V ++F L+ +G I+ LD EE+
Sbjct: 255 LALGTQLLVVNATDPDEGVNAEVRYSF-RYVDDKAAQVFKLDCNSGTISTIGELDHEESG 313
Query: 325 IHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIA 384
+++ V A D + ARA V I V DVNDN P + L + S + E P T IA
Sbjct: 314 FYQMEVQAMDNAGYSARAKVLITVLDVNDNAPEVVLTSLASSV------PENSPRGTLIA 367
Query: 385 LITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDS 444
L+ V+D+D++ NG+VICFI+ +PF L+ Y N Y L T +LD E ++ + A+D
Sbjct: 368 LLNVNDQDSEENGQVICFIQGNLPFKLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDR 427
Query: 445 GKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADI 504
G P L+ + + + D NDNPP+F Q + ENN RG+ L +++A D D +NA I
Sbjct: 428 GTPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQI 487
Query: 505 VYQLGPN-------ASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAA 557
Y L N +S+ ++ TGVL A FD E+ V ARDNG PPL S +
Sbjct: 488 TYSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVS 547
Query: 558 VIVTVLDENDNSPKFTHNHFQFFVSENL--------PKYSTVGVITVTDADAGENKAVTL 609
+ + VLD+NDN+P+ + S + P Y V+ V D D+G+N ++
Sbjct: 548 LSLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAV-DRDSGQNAWLSY 606
Query: 610 SILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMD 667
+L ++ F + ++G +++ + + V D GQPP S+T +T+ V D
Sbjct: 607 RLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVAD 666
Score = 244 bits (622), Expect = 5e-64
Identities = 195/670 (29%), Positives = 310/670 (46%), Gaps = 52/670 (7%)
Query: 204 LIVQQNLDREQKDTYVMKIKVE-DGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
L+ +DRE+ +K ++ D K ++V V D+NDN P F+E ++E+ I
Sbjct: 84 LVTAGRIDREELCMGAIKCQLNLDILMEDKVKIYGVEVEVRDINDNAPYFRESELEIKIS 143
Query: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATK-RLFALNNTTGL----ITVQRS 317
ENA HA D DIG N+ Y +++P T L N G + ++R+
Sbjct: 144 ENAATEMRFPLPHAWDPDIGKNSLQSY----ELSPNTHFSLIVQNGADGSKYPELVLKRA 199
Query: 318 LDREETAIHKVTVLASDGSSTPAR---ATVTINVTDVNDNPPNIDLRYIISPINGTVYLS 374
LDREE A H + + ASDG P R A + + V D NDN P + +
Sbjct: 200 LDREEKAAHHLVLTASDGGD-PVRTGTARIRVMVLDANDNAP------AFAQPEYRASVP 252
Query: 375 EKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD---NQYLLETSSLLDYEG 431
E + T++ ++ +D D VN +V + R V V+ N + T LD+E
Sbjct: 253 ENLALGTQLLVVNATDPDEGVNAEVR-YSFRYVDDKAAQVFKLDCNSGTISTIGELDHEE 311
Query: 432 TKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTI 491
+ + ++ A D+ S L+ V D NDN P + SV EN+ RG + +
Sbjct: 312 SGFYQMEVQAMDNAGYSARAKVLITVL--DVNDNAPEVVLTSLASSVPENSPRGTLIALL 369
Query: 492 SATDEDSGKNADIVYQLGPNASFFDLDRKTG---VLTASRVFDREEQERFIFTVTARDNG 548
+ D+DS +N ++ + N F L++ G L V DRE+ + TVTA D G
Sbjct: 370 NVNDQDSEENGQVICFIQGNLPF-KLEKSYGNYYSLVTDIVLDREQVPSYNITVTATDRG 428
Query: 549 TPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVT 608
TPPL ++ + + V D NDN P F + ++ EN P+ ++ +T D D EN +T
Sbjct: 429 TPPLSTETHISLNVADTNDNPPVFPQASYSAYIPENNPRGVSLVSVTAHDPDCEENAQIT 488
Query: 609 LSILNDN------DNFV-LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKV 661
S+ + ++V ++ +GV+ + SFD EQ V A D G PP SS +
Sbjct: 489 YSLAENTIQGASLSSYVSINSDTGVLYALSSFDYEQFRDLQVKVMARDNGHPPLSSNVSL 548
Query: 662 TINVMDVNDNSPVVISPP----SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTI 717
++ V+D NDN+P ++ P +T +L P SA PG +V +V AVD D+G NA L Y +
Sbjct: 549 SLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQNAWLSYRL 608
Query: 718 VSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDT 777
+ + GLF + TG + D LVV + D G P T+ L +
Sbjct: 609 LKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTLTVAVADSI 668
Query: 778 AGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVIFVTVLVR 837
+ DL ++E+P + D + YL + +A ++ + V++ + + +R
Sbjct: 669 ---PQVLADL--GSLESPANSETSDLTL------YLVVAVAAVSCVFLAFVILLLALRLR 717
Query: 838 CRHASRFKAA 847
H SR A
Sbjct: 718 RWHKSRLLQA 727
>gi|165932370 FAT tumor suppressor homolog 4 [Homo sapiens]
Length = 4981
Score = 354 bits (908), Expect = 3e-97
Identities = 263/805 (32%), Positives = 414/805 (51%), Gaps = 67/805 (8%)
Query: 3 LRDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASL 62
LR F+LL+ L + A ++ ++ + EE P +G I T
Sbjct: 25 LRVFWLLSLLPGQAWVHGAEPRQ-VFQVLEEQPPGTLVGTIQ-------------TRPGF 70
Query: 63 VYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDF 122
YRL L ++SSTG ++TTS IDRE L + + +V+L +
Sbjct: 71 TYRLSESHA---LFAINSSTGALYTTST-IDRESLPSDV-----------INLVVLSSAP 115
Query: 123 FRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQH--YE 180
+++++V+D NDNAP+FP P I ++ E++ + + +ATD D G NGV H Y
Sbjct: 116 TYPTEVRVLVRDLNDNAPVFPDPSIVVTFKEDSSSGRQVILDTATDSDIGSNGVDHRSYR 175
Query: 181 LLNGQSV--FGLDIVETPEGE-KWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAI 237
++ G F LDI P GE + L+ + LDRE Y + ++VED G P++
Sbjct: 176 IIRGNEAGRFRLDITLNPSGEGAFLHLVSKGGLDREVTPQYQLLVEVEDKGEPKRRGYLQ 235
Query: 238 LQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAP 297
+ VTV D+NDN PVF + +PE+A VG+SV+Q+ A DAD G+NA+IRY + P
Sbjct: 236 VNVTVQDINDNPPVFGSSHYQAGVPEDAVVGSSVLQVAAADADEGTNADIRYRLQDEGTP 295
Query: 298 ATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGS--STPARATVTINVTDVNDNP 355
F ++ TGLITV+ LD E + +TV A D S RA I + DVNDN
Sbjct: 296 -----FQMDPETGLITVREPLDFEARRQYSLTVQAMDRGVPSLTGRAEALIQLLDVNDND 350
Query: 356 PNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD-VNGKVICFI---EREVPFHL 411
P + RY + + E V T +AL+TV+D D+ NG + I + F +
Sbjct: 351 PVVKFRY-FPATSRYASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV 409
Query: 412 K-AVYDNQYLLETSSLLDYEGTKEFSFKIVASDS-GKP------SLNQTALVRVKLEDEN 463
+ + N L++ +S LD E ++ + SD+ G P + + A + + + D N
Sbjct: 410 QSSKVPNLSLIKVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDIN 469
Query: 464 DNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKT 521
D+PP+F+Q V +++SE G Y++ ISATD DSG NA++ Y + G +F + +
Sbjct: 470 DHPPVFSQQVYRVNLSEEAPPGSYVSGISATDGDSGLNANLRYSIVSGNGLGWFHISEHS 529
Query: 522 GVLT--ASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTH-NHFQ 578
G++T +S DRE + + ++ARD G P S A ++VT+LD ND P F+ +
Sbjct: 530 GLVTTGSSGGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFSQPEGYD 589
Query: 579 FFVSENLPKYSTVGVITVTDADAGENKAVTLSIL---NDNDNFVLDPYSGVIKSNVSFDR 635
V EN P + + ++ TD D G+N V S+ D +F LDP SG + + S DR
Sbjct: 590 VSVVENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGRLSTISSLDR 649
Query: 636 EQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGS 695
E+Q+ Y+ V ATD G PP+SS A++ ++++D+NDNSPV F + + GS
Sbjct: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPV---QYFAHIKENEPGGS 706
Query: 696 VVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNI 755
+ V A D D G N +KY+I +G ++ F+++ +G I+ + ++L +
Sbjct: 707 YITTVSATDPDLGTNGTVKYSISAG-DRSRFQVNAQSGVISTRMALDREEKTAYQLQIVA 765
Query: 756 SDLGYPKSLHTLVLVFLYVNDTAGN 780
+D G +S + +V + V DT N
Sbjct: 766 TDGGNLQSPNQ-AIVTITVLDTQDN 789
Score = 306 bits (783), Expect = 1e-82
Identities = 236/739 (31%), Positives = 352/739 (47%), Gaps = 51/739 (6%)
Query: 36 ENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDRE 95
ENV +G ++ ++A+T S + L++ + ++ TG++ TT+N IDRE
Sbjct: 804 ENVALG-----YHVGSVSASTMDLNSNISYLITTGDQKGMFAINQVTGQL-TTANVIDRE 857
Query: 96 KLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENT 155
+ + F++L+VV + I VKD NDN+P F + ++++ EN
Sbjct: 858 E-----------QSFYQLKVVASGGTVTGDTMVNITVKDLNDNSPHFLQAIESVNVVENW 906
Query: 156 LINSRFPIPSATDPDTGFNGVQHYELL-NGQSVFGLDIVETPEGEKWPQLIVQQNLDREQ 214
A DPD G NG+ Y L N +++F ++ EK + + LD
Sbjct: 907 QAGHSIFQAKAVDPDEGVNGMVLYSLKQNPKNLFAIN-------EKNGTISLLGPLD-VH 958
Query: 215 KDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQL 274
+Y ++I D G PQ SS+ IL V V DVNDN PVF + EV + E+ PV + ++
Sbjct: 959 AGSYQIEILASDMGVPQLSSSVILTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKV 1018
Query: 275 HATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
A+D D G+N EI Y +F G + ++ LDRE + + V+ASD
Sbjct: 1019 QASDKDSGANGEIAYTIAEGNTGDAFGIF----PDGQLYIKSELDRELQDRYVLMVVASD 1074
Query: 335 GSSTPARATVTINV--TDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKD 392
+ P ATV + V DVNDN P + + N T Y E+ + + ++ DKD
Sbjct: 1075 RAVEPLSATVNVTVILEDVNDNRP------LFNSTNYTFYFEEEQRAGSFVGKVSAVDKD 1128
Query: 393 TDVNGKVICFIEREVP-FHLKAV---YDNQYLLETSSLLDYEGTKEFSFKIVASDSGKPS 448
NG+V E P F L A+ N + + SL+ GT FSF ++A+D G P
Sbjct: 1129 FGPNGEVRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQ 1188
Query: 449 -LNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
L A V V ++D NDN P F + + ++SE+ + +SA+D D G N I Y
Sbjct: 1189 PLKDQATVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYS 1248
Query: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
+ G F +D +G +T D E + + A D+GT PL S + + +LDE
Sbjct: 1249 IIKGNEERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDE 1308
Query: 566 NDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSI--LNDNDNFVLDPY 623
NDN+P F + V EN+ V +T TD+D+G+N + SI N++ F + P
Sbjct: 1309 NDNTPSFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPN 1368
Query: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
+G I D E QS Y ++ A D G+PPRSST V I+V D NDN P S P
Sbjct: 1369 TGSIFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPP---SFPPGDI 1425
Query: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKG-LFRIDPVTGNITLEEKPA 742
FK + + G+ V V A D D +N +L YTI+ +G F ID V G I +
Sbjct: 1426 FKSIVENIPIGTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEID 1485
Query: 743 PTDVGLHRLVVNISDLGYP 761
L L V +D P
Sbjct: 1486 REFANLFELTVKANDQAVP 1504
Score = 299 bits (765), Expect = 1e-80
Identities = 214/671 (31%), Positives = 334/671 (49%), Gaps = 58/671 (8%)
Query: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQS- 186
+ + V D NDN+P+F +++ E+ +NSRF A+D D+G NG Y + G +
Sbjct: 982 LTVYVHDVNDNSPVFDQLSYEVTLSESEPVNSRFFKVQASDKDSGANGEIAYTIAEGNTG 1041
Query: 187 -VFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
FG+ P+G QL ++ LDRE +D YV+ + D S+T + V + DV
Sbjct: 1042 DAFGI----FPDG----QLYIKSELDRELQDRYVLMVVASDRAVEPLSATVNVTVILEDV 1093
Query: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
NDNRP+F + E G+ V ++ A D D G N E+RY F V P F L
Sbjct: 1094 NDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGEVRYSF-EMVQPD----FEL 1148
Query: 306 NNTTGLITVQRSLDREE------TAIHKVTVLASD-GSSTPAR--ATVTINVTDVNDNPP 356
+ +G IT DRE TA+ TV+A+D G P + ATV + + D+NDN P
Sbjct: 1149 HAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQATVHVYMKDINDNAP 1208
Query: 357 NIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYD 416
+++ T+ SE T++ ++ SD D NG + I +K +
Sbjct: 1209 ----KFLKDFYQATI--SESAANLTQVLRVSASDVDEGNNGLIHYSI-------IKGNEE 1255
Query: 417 NQYLLETSS-------LLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIF 469
Q+ ++++S LDYE T +S I A DSG LN T + + + DENDN P F
Sbjct: 1256 RQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTPSF 1315
Query: 470 NQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQL--GPNASFFDLDRKTGVLTAS 527
+ + + V EN R G +++++ATD DSG NAD+ Y + N F + TG + +
Sbjct: 1316 PKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGSIFLA 1375
Query: 528 RVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPK 587
+ D E Q + +TA+D G PP S +V++ V D NDN P F + EN+P
Sbjct: 1376 KKLDFETQSLYKLNITAKDQGRPPRSSTMSVVIHVRDFNDNPPSFPPGDIFKSIVENIPI 1435
Query: 588 YSTVGVITVTDADAGENKAVTLSILND---NDNFVLDPYSGVIKSNVSFDREQQSSYTFD 644
++V +T D DA N ++ +I+ ++F +D G I +N DRE + +
Sbjct: 1436 GTSVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNAEIDREFANLFELT 1495
Query: 645 VKATDGGQP---PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVF 701
VKA D P R + VTI V D+NDN P+ IS + + SA+ GSV+ +
Sbjct: 1496 VKANDQAVPIETRRYALKNVTILVTDLNDNVPMFISQNALAA----DPSAVIGSVLTTIM 1551
Query: 702 AVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYP 761
A D D G N E++Y I++G+ F +D +G++ + P+ + ++ L+V+ +DLG
Sbjct: 1552 AADPDEGANGEIEYEIINGDT-DTFIVDRYSGDLRVASALVPSQL-IYNLIVSATDLGPE 1609
Query: 762 KSLHTLVLVFL 772
+ T L +
Sbjct: 1610 RRKSTTELTII 1620
Score = 295 bits (755), Expect = 2e-79
Identities = 222/717 (30%), Positives = 350/717 (48%), Gaps = 53/717 (7%)
Query: 35 PENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDR 94
PEN P+ ++ ++ I ++ + Y + S ++ TG++ + S +D
Sbjct: 2577 PENQPVSSL-----VTTITGSSLRGEPMSYYIAS-GNLGNTFQIDQLTGQV-SISQPLDF 2629
Query: 95 EKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPEN 154
EK+ + E + F F K+ I V D NDNAP+F I EN
Sbjct: 2630 EKIQKYVVWIEARDGGFP--------PFSSYEKLDITVLDVNDNAPIFKEDPFISEILEN 2681
Query: 155 TLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQ 214
L + SA D D+G NG YE++NG I ++ + LDRE+
Sbjct: 2682 -LSPRKILTVSAMDKDSGPNGQLDYEIVNGNMENSFSI-----NHATGEIRSVRPLDREK 2735
Query: 215 KDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQL 274
YV+ IK D G+P +S++ + + + D NDN P F + H+PEN+P+G +V ++
Sbjct: 2736 VSHYVLTIKSSDKGSPSQSTSVKVMINILDENDNAPRFSQ-IFSAHVPENSPLGYTVTRV 2794
Query: 275 HATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASD 334
+D DIG NA RY P F +N +TG I + R L+RE+T +++ V A D
Sbjct: 2795 TTSDEDIGINAISRYSIMDASLP-----FTINPSTGDIVISRPLNREDTDRYRIRVSAHD 2849
Query: 335 GSSTPARATVTINVTDVNDNPPNIDLR--YIISPINGTVYLSEKDPVNTKIALITVSDKD 392
T + VTI VTD+NDN P Y+ P E + +K+ + +D D
Sbjct: 2850 SGWTVS-TDVTIFVTDINDNAPRFSRTSYYLDCP--------ELTEIGSKVTQVFATDPD 2900
Query: 393 TDVNGKVICFIEREVP-FHLKAVYD---NQYLLETSSLLDYEGTK--EFSFKIVASDSGK 446
NG+V FI+ + F + A N+ +L+ ++ + SF + +SD GK
Sbjct: 2901 EGSNGQVFYFIKSQSEYFRINATTGEIFNKQILKYQNVTGFSNVNINRHSFIVTSSDRGK 2960
Query: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDE-DSGKNADIV 505
PSL V + + D NDN P F + V++N + G L ++A D+ D G N+++
Sbjct: 2961 PSLISETTVTINIVDSNDNAPQFLKSKYFTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVE 3020
Query: 506 YQLGPNASF--FDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVL 563
Y + + F LD TG ++ + + + F TVTA+D G PPL SQA V +TV
Sbjct: 3021 YFISNDNHLGKFKLDNDTGWISVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVT 3080
Query: 564 DENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN--FVLD 621
+EN ++P+F+ +H + E+ S V ++ D DA N + SI + N+ F ++
Sbjct: 3081 EENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEEGIFAIN 3140
Query: 622 PYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSN 681
+G++ + D E + + A DGG R+ VT+NV+DVNDNSPV + S+
Sbjct: 3141 SSTGILTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFL---SD 3197
Query: 682 TSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
F V +A G+ V + A D D+G NA + YT+ S ++ LF IDP TG IT +
Sbjct: 3198 DYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYTVQS-SDSDLFVIDPNTGVITTQ 3253
Score = 294 bits (753), Expect = 3e-79
Identities = 239/766 (31%), Positives = 362/766 (47%), Gaps = 66/766 (8%)
Query: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
+ EN P G+ +S + GT+ ++ Y + AGD +V++ +G + +T +D
Sbjct: 698 IKENEPGGSYIT--TVSATDPDLGTNGTVKYSI--SAGDRSRFQVNAQSG-VISTRMALD 752
Query: 94 REKLCAGASYAEENECFFELEVVIL-------PNDFFRLIKIKIIVKDTNDNAPMFPSPV 146
RE+ A ++L++V PN + I V DT DN P+F
Sbjct: 753 REEKTA-----------YQLQIVATDGGNLQSPNQAI----VTITVLDTQDNPPVFSQVA 797
Query: 147 INISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIV 206
+ + EN + SA+ D N Y + G G+ + G QL
Sbjct: 798 YSFVVFENVALGYHVGSVSASTMD--LNSNISYLITTGDQK-GMFAINQVTG----QLTT 850
Query: 207 QQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
+DRE++ Y +K+ V GGT + ++ +TV D+NDN P F + V++ EN
Sbjct: 851 ANVIDREEQSFYQLKV-VASGGT--VTGDTMVNITVKDLNDNSPHFLQAIESVNVVENWQ 907
Query: 267 VGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIH 326
G S+ Q A D D G N + Y + K LFA+N G I++ LD +
Sbjct: 908 AGHSIFQAKAVDPDEGVNGMVLY----SLKQNPKNLFAINEKNGTISLLGPLD-VHAGSY 962
Query: 327 KVTVLASDGSSTPARATV--TINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIA 384
++ +LASD ++V T+ V DVNDN P + ++ V LSE +PVN++
Sbjct: 963 QIEILASDMGVPQLSSSVILTVYVHDVNDNSP------VFDQLSYEVTLSESEPVNSRFF 1016
Query: 385 LITVSDKDTDVNGKVICFIEREVPFHLKAVY-DNQYLLETSSLLDYEGTKEFSFKIVASD 443
+ SDKD+ NG++ I ++ D Q L S LD E + +VASD
Sbjct: 1017 KVQASDKDSGANGEIAYTIAEGNTGDAFGIFPDGQ--LYIKSELDRELQDRYVLMVVASD 1074
Query: 444 SGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNAD 503
L+ T V V LED NDN P+FN E R G ++ +SA D+D G N +
Sbjct: 1075 RAVEPLSATVNVTVILEDVNDNRPLFNSTNYTFYFEEEQRAGSFVGKVSAVDKDFGPNGE 1134
Query: 504 IVYQLGPNASFFDLDRKTGVLTASRVFDREEQER------FIFTVTARDNGTP-PLQSQA 556
+ Y F+L +G +T + FDRE R F FTV A D G P PL+ QA
Sbjct: 1135 VRYSFEMVQPDFELHAISGEITNTHQFDRESLMRRRGTAVFSFTVIATDQGIPQPLKDQA 1194
Query: 557 AVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND 616
V V + D NDN+PKF + +Q +SE+ + V ++ +D D G N + SI+ N+
Sbjct: 1195 TVHVYMKDINDNAPKFLKDFYQATISESAANLTQVLRVSASDVDEGNNGLIHYSIIKGNE 1254
Query: 617 --NFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPV 674
F +D SG + D E +Y+ ++A D G P +ST + I+++D NDN+P
Sbjct: 1255 ERQFAIDSTSGQVTLIGKLDYEATPAYSLVIQAVDSGTIPLNSTCTLNIDILDENDNTP- 1313
Query: 675 VISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
S P +T F V + G +V+ V A D D+G NA+L Y+I NN G F I P TG+
Sbjct: 1314 --SFPKSTLFVDVLENMRIGELVSSVTATDSDSGDNADLYYSITGTNNHGTFSISPNTGS 1371
Query: 735 ITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
I L +K L++L + D G P T+ +V ++V D N
Sbjct: 1372 IFLAKKLDFETQSLYKLNITAKDQGRPPRSSTMSVV-IHVRDFNDN 1416
Score = 286 bits (732), Expect = 8e-77
Identities = 232/760 (30%), Positives = 363/760 (47%), Gaps = 61/760 (8%)
Query: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
L EN+P+G+ N++ +A G ++ L Y + S GD+ L + + + +D
Sbjct: 1953 LMENLPVGSTVLVFNVT--DADDGINSQLTYSIAS--GDS-LGQFTVDKNGVLKVLKALD 2007
Query: 94 REKLCAGASYAEENECFFELEVVI--LP----NDFFRLIKIKIIVKDTNDNAPMFPSPVI 147
RE ++ F+ L V + LP + F ++ II+ D NDN P F SP +
Sbjct: 2008 RE-----------SQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKL 2056
Query: 148 NISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQ 207
IPENT I++ ATDPD+G N Y LLN + + T +GE + +
Sbjct: 2057 TY-IPENTPIDTVVFKAQATDPDSGPNSYIEYTLLN--PLGNKFSIGTIDGE----VRLT 2109
Query: 208 QNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
LDRE+ Y + + D G P SS+ + V V D+NDN P+F + +V I EN
Sbjct: 2110 GELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLT 2169
Query: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
GT +IQ+ A D D G+N ++RY V T + F +++ TG ITV + LDRE+T +
Sbjct: 2170 GTDIIQVFAADGDEGTNGQVRY---GIVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYH 2226
Query: 328 VTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIAL 385
+TV A+D STP T T+++ D+ND P +L SP + V + I
Sbjct: 2227 LTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFEL----SPYSVNV-PENLGTLPRTILQ 2281
Query: 386 ITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
+ D D N K+ + + F L A + L + LD E + F I A+
Sbjct: 2282 VVARDDDRGSNSKLSYVLFGGNEDNAFTLSASGE----LGVTQSLDRETKERFVLMITAT 2337
Query: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
DSG P+L T + V ++D NDN P F ++ E+ G + ++A+D D+ KNA
Sbjct: 2338 DSGSPALTGTGTINVIVDDVNDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNA 2397
Query: 503 DIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTP-PLQSQAAVIVT 561
++ +G N S F ++ TG + S + DRE ++ + V D G+P PL S +V+VT
Sbjct: 2398 -VIRIIGGN-SQFTINPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVT 2455
Query: 562 VLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDN-DNFVL 620
V D NDN P+F H+ + + S V +TVTDAD G N + S+ N + F +
Sbjct: 2456 VTDVNDNPPRFQHHPYVTHIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHI 2515
Query: 621 DPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPS 680
DP G I + + S TF V DGG P++ + VT+ ++ D V +
Sbjct: 2516 DPLRGAIMA--AGPLNGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKVRAKEQT 2573
Query: 681 NTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEK 740
+ P+S++ V + + + Y I SGN F+ID +TG +++ +
Sbjct: 2574 FMFPENQPVSSL-------VTTITGSSLRGEPMSYYIASGNLGNTFQIDQLTGQVSISQP 2626
Query: 741 PAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVNDTA 778
+ + + + D G+P S L + L VND A
Sbjct: 2627 LDFEKIQKYVVWIEARDGGFPPFSSYEKLDITVLDVNDNA 2666
Score = 281 bits (718), Expect = 3e-75
Identities = 221/757 (29%), Positives = 351/757 (46%), Gaps = 63/757 (8%)
Query: 40 IGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCA 99
IG+ K + ++ ++A G +A + Y ++S A D+ ++ +G++ T R+DRE+
Sbjct: 1753 IGDGSKIMQLTAMDADEGANALVTYTIISGADDS--FRIDPESGDLIAT-RRLDRERRSK 1809
Query: 100 GASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINS 159
+ ++ ++ +I I V D ND+ P F PV + IPE+T+ S
Sbjct: 1810 YSLLVRADDGLQSSDM-----------RINITVSDVNDHTPKFSRPVYSFDIPEDTIPGS 1858
Query: 160 RFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYV 219
ATD D+G NG Y ++N G+ + G + + LD E + Y+
Sbjct: 1859 LVAAILATDDDSGVNGEITY-IVNEDDEDGIFFLNPITG----VFNLTRLLDYEVQQYYI 1913
Query: 220 MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDA 279
+ ++ EDGG + +T + + DVNDN P+F + EN PVG++V+ + TDA
Sbjct: 1914 LTVRAEDGG--GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDA 1971
Query: 280 DIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTP 339
D G N+++ Y +A + G++ V ++LDRE + + + V D P
Sbjct: 1972 DDGINSQLTY----SIASGDSLGQFTVDKNGVLKVLKALDRESQSFYNLVVQVHDLPQIP 2027
Query: 340 A-----RATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALITVSDKDTD 394
A A V+I + DVNDNPP +SP Y+ E P++T + +D D+
Sbjct: 2028 ASRFTSTAQVSIILLDVNDNPPT-----FLSP--KLTYIPENTPIDTVVFKAQATDPDSG 2080
Query: 395 VNGKVICFIEREVPFHLKAVYDNQYLLET-------SSLLDYEGTKEFSFKIVASDSGKP 447
N +IE + L N++ + T + LD E ++ +VA+D G+P
Sbjct: 2081 PNS----YIE----YTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQP 2132
Query: 448 SLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIVYQ 507
SL+ + V V + D NDN PIF Q + ++ ++EN G + + A D D G N + Y
Sbjct: 2133 SLSSSTEVVVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYG 2192
Query: 508 L--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTVLDE 565
+ G F +D TG +T ++ DRE+ + TV A D G+ P + V + +LD
Sbjct: 2193 IVNGNTNQEFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDI 2252
Query: 566 NDNSPKFTHNHFQFFVSENLPKY-STVGVITVTDADAGENKAVTLSILNDN-DNFVLDPY 623
ND P F + + V ENL T+ + D D G N ++ + N DN
Sbjct: 2253 NDFVPVFELSPYSVNVPENLGTLPRTILQVVARDDDRGSNSKLSYVLFGGNEDNAFTLSA 2312
Query: 624 SGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPPSNTS 683
SG + S DRE + + + ATD G P + T + + V DVNDN P S
Sbjct: 2313 SGELGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDVNDNVPTF---ASKAY 2369
Query: 684 FKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLEEKPAP 743
F +P A G+ V V A D D NA ++ I+ GN++ F I+P TG I
Sbjct: 2370 FTTIPEDAPTGTDVLLVNASDADASKNAVIR--IIGGNSQ--FTINPSTGQIITSALLDR 2425
Query: 744 TDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGN 780
+ LVV SD G P+ L + V + V D N
Sbjct: 2426 ETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDN 2462
Score = 275 bits (702), Expect = 2e-73
Identities = 226/747 (30%), Positives = 345/747 (46%), Gaps = 61/747 (8%)
Query: 34 LPENVPIGNIPKDLNISHINAAT--GTSASLVYRLVSKAGDAPLV----KVSSSTGEIFT 87
L E PIG N+ I AA+ G+ A + Y +VS + V + TG I
Sbjct: 1638 LKEGEPIGT-----NVISIEAASPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTG-IIQ 1691
Query: 88 TSNRIDREKLCAGASYAEENECFFELEVVILPNDFF----RLIKIKIIVKDTNDNAPMFP 143
T+ +DRE + C + ++V + + +++I ++D NDN P+FP
Sbjct: 1692 TAAILDRE----------QGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFP 1741
Query: 144 SPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNG-QSVFGLDIVETPEGEKWP 202
+ ++++++ EN S+ +A D D G N + Y +++G F +D PE
Sbjct: 1742 TDMLDLTVEENIGDGSKIMQLTAMDADEGANALVTYTIISGADDSFRID----PES---G 1794
Query: 203 QLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIP 262
LI + LDRE++ Y + ++ +DG +SS + +TVSDVND+ P F IP
Sbjct: 1795 DLIATRRLDRERRSKYSLLVRADDG---LQSSDMRINITVSDVNDHTPKFSRPVYSFDIP 1851
Query: 263 ENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREE 322
E+ G+ V + ATD D G N EI YI +F LN TG+ + R LD E
Sbjct: 1852 EDTIPGSLVAAILATDDDSGVNGEITYIVNEDDEDG---IFFLNPITGVFNLTRLLDYEV 1908
Query: 323 TAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
+ +TV A DG V N+ DVNDNPP I S + + L E PV +
Sbjct: 1909 QQYYILTVRAEDGGGQFTTIRVYFNILDVNDNPP------IFSLNSYSTSLMENLPVGST 1962
Query: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
+ + V+D D +N ++ I V D +L+ LD E ++ +
Sbjct: 1963 VLVFNVTDADDGINSQLTYSIASGDSLGQFTV-DKNGVLKVLKALDRESQSFYNLVVQVH 2021
Query: 443 DSGK---PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSG 499
D + TA V + L D NDNPP F P + + EN + ATD DSG
Sbjct: 2022 DLPQIPASRFTSTAQVSIILLDVNDNPPTFLSPKLTY-IPENTPIDTVVFKAQATDPDSG 2080
Query: 500 KNADIVYQ-LGPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAV 558
N+ I Y L P + F + G + + DREE + TV A D G P L S V
Sbjct: 2081 PNSYIEYTLLNPLGNKFSIGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEV 2140
Query: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN- 617
+V VLD NDN+P F ++ ++EN + + + D D G N V I+N N N
Sbjct: 2141 VVMVLDINDNNPIFAQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQ 2200
Query: 618 -FVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVI 676
F +D +G I DRE+ +Y V+ATD G PR+ T+ V+I ++D+ND PV
Sbjct: 2201 EFRIDSVTGAITVAKPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDINDFVPVFE 2260
Query: 677 SPPSNTSFKLVP--LSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGN 734
P + + VP L +P +++ +V A D D G N++L Y + GN F + +G
Sbjct: 2261 LSPYSVN---VPENLGTLPRTIL-QVVARDDDRGSNSKLSYVLFGGNEDNAFTLS-ASGE 2315
Query: 735 ITLEEKPAPTDVGLHRLVVNISDLGYP 761
+ + + L++ +D G P
Sbjct: 2316 LGVTQSLDRETKERFVLMITATDSGSP 2342
Score = 251 bits (641), Expect = 3e-66
Identities = 202/673 (30%), Positives = 315/673 (46%), Gaps = 51/673 (7%)
Query: 128 IKIIVKDTNDNAPMFPSPVINISIPEN--TLINSRFPIPSATDPDTGFNGVQHYELLNGQ 185
+ I++ D ND P+F ++++PEN TL + + A D D G N Y L G
Sbjct: 2245 VSIVLLDINDFVPVFELSPYSVNVPENLGTLPRTILQVV-ARDDDRGSNSKLSYVLFGGN 2303
Query: 186 SVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDV 245
+ + E L V Q+LDRE K+ +V+ I D G+P + T + V V DV
Sbjct: 2304 EDNAFTLSASGE------LGVTQSLDRETKERFVLMITATDSGSPALTGTGTINVIVDDV 2357
Query: 246 NDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL 305
NDN P F IPE+AP GT V+ ++A+DAD NA IR I G F +
Sbjct: 2358 NDNVPTFASKAYFTTIPEDAPTGTDVLLVNASDADASKNAVIRIIGG-------NSQFTI 2410
Query: 306 NNTTGLITVQRSLDREETAIHKVTVLASD-GSSTP--ARATVTINVTDVNDNPPNIDLRY 362
N +TG I LDRE + + V+ SD GS P + +V + VTDVNDNPP
Sbjct: 2411 NPSTGQIITSALLDRETKDNYTLVVVCSDAGSPEPLSSSTSVLVTVTDVNDNPPRFQHHP 2470
Query: 363 IISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFI--EREVPFHLKAVYDNQYL 420
++ ++ + + +TV+D D N ++ + FH+ + +
Sbjct: 2471 YVT------HIPSPTLPGSFVFAVTVTDADIGPNSELHYSLSGRNSEKFHIDPL--RGAI 2522
Query: 421 LETSSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
+ L G E +F + D G + V V+ ++ D P + E
Sbjct: 2523 MAAGPL---NGASEVTFSVHVKDGGSFPKTDSTTVTVRFVNKADFPKV-RAKEQTFMFPE 2578
Query: 481 NNRRGLYLTTISATDEDSGKNADIVYQLGPNASFFDLDRKTGVLTASRVFDREEQERFIF 540
N +TTI+ + G+ G + F +D+ TG ++ S+ D E+ ++++
Sbjct: 2579 NQPVSSLVTTITGSSL-RGEPMSYYIASGNLGNTFQIDQLTGQVSISQPLDFEKIQKYVV 2637
Query: 541 TVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT--D 598
+ ARD G PP S + +TVLD NDN+P F + F+SE L S ++TV+ D
Sbjct: 2638 WIEARDGGFPPFSSYEKLDITVLDVNDNAPIFKEDP---FISEILENLSPRKILTVSAMD 2694
Query: 599 ADAGENKAVTLSILNDN--DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS 656
D+G N + I+N N ++F ++ +G I+S DRE+ S Y +K++D G P +S
Sbjct: 2695 KDSGPNGQLDYEIVNGNMENSFSINHATGEIRSVRPLDREKVSHYVLTIKSSDKGSPSQS 2754
Query: 657 STAKVTINVMDVNDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYT 716
++ KV IN++D NDN+P S VP ++ G V V D D G+NA +Y+
Sbjct: 2755 TSVKVMINILDENDNAPRF----SQIFSAHVPENSPLGYTVTRVTTSDEDIGINAISRYS 2810
Query: 717 IVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVND 776
I+ + F I+P TG+I + D +R+ V+ D G+ S + V +ND
Sbjct: 2811 IMDASLP--FTINPSTGDIVISRPLNREDTDRYRIRVSAHDSGWTVSTDVTIFV-TDIND 2867
Query: 777 TA---GNASYIYD 786
A SY D
Sbjct: 2868 NAPRFSRTSYYLD 2880
Score = 248 bits (634), Expect = 2e-65
Identities = 230/765 (30%), Positives = 359/765 (46%), Gaps = 58/765 (7%)
Query: 30 IREELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTS 89
I + + EN+PIG ++++ + + L Y ++ + + G I+T +
Sbjct: 1425 IFKSIVENIPIGT--SVISVTAHDPDADINGQLSYTIIQQMPRGNHFTIDEVKGTIYTNA 1482
Query: 90 NRIDREKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPVINI 149
IDRE + N+ + V + + L + I+V D NDN PMF S
Sbjct: 1483 E-IDREFANLFELTVKAND-----QAVPIETRRYALKNVTILVTDLNDNVPMFISQNALA 1536
Query: 150 SIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGE-KWPQLIVQQ 208
+ P + +I S A DPD G NG YE++NG + IV+ G+ + +V
Sbjct: 1537 ADP-SAVIGSVLTTIMAADPDEGANGEIEYEIINGDT--DTFIVDRYSGDLRVASALVPS 1593
Query: 209 NLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVG 268
L Y + + D G ++ ST L + + ++ PVF + + + E P+G
Sbjct: 1594 QL------IYNLIVSATDLGPERRKSTTELTIILQGLDG--PVFTQPKYITILKEGEPIG 1645
Query: 269 TSVIQLHATDADIGSNAEIR-YIFGAQVAPAT-KRLFALNNTTGLITVQRSLDREETA-I 325
T+VI + A + GS A + YI + T RLF + TG+I LDRE+ A +
Sbjct: 1646 TNVISIEAA-SPRGSEAPVEYYIVSVRCEEKTVGRLFTIGRHTGIIQTAAILDREQGACL 1704
Query: 326 HKVTVLASDGSST---PARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
+ V V A + S+ RA V I + D+NDNPP + + + E +K
Sbjct: 1705 YLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDML------DLTVEENIGDGSK 1758
Query: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
I +T D D N V I + ++ L+ T LD E ++S +V +
Sbjct: 1759 IMQLTAMDADEGANALVTYTIISGADDSFRIDPESGDLIATRR-LDRERRSKYSL-LVRA 1816
Query: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
D G S + + + + D ND+ P F++PV + E+ G + I ATD+DSG N
Sbjct: 1817 DDGLQSSDMR--INITVSDVNDHTPKFSRPVYSFDIPEDTIPGSLVAAILATDDDSGVNG 1874
Query: 503 DIVYQLGPN--ASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIV 560
+I Y + + F L+ TGV +R+ D E Q+ +I TV A D G + V
Sbjct: 1875 EITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGGGQ--FTTIRVYF 1932
Query: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDND--NF 618
+LD NDN P F+ N + + ENLP STV V VTDAD G N +T SI + + F
Sbjct: 1933 NILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLTYSIASGDSLGQF 1992
Query: 619 VLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRS---STAKVTINVMDVNDNSPVV 675
+D +GV+K + DRE QS Y V+ D Q P S STA+V+I ++DVNDN P
Sbjct: 1993 TVDK-NGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSIILLDVNDNPPTF 2051
Query: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVS--GNNKGLFRIDPVTG 733
+SP +P + +VV + A D D+G N+ ++YT+++ GN F I + G
Sbjct: 2052 LSP----KLTYIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNK---FSIGTIDG 2104
Query: 734 NITLEEKPAPTDVGLHRLVVNISDLGYP--KSLHTLVLVFLYVND 776
+ L + +V + L V +D G P S +V++ L +ND
Sbjct: 2105 EVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDIND 2149
Score = 248 bits (633), Expect = 2e-65
Identities = 223/773 (28%), Positives = 357/773 (46%), Gaps = 63/773 (8%)
Query: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
+PE+ +G+ L ++ +A GT+A + YRL + ++ TG + T +D
Sbjct: 259 VPEDAVVGS--SVLQVAAADADEGTNADIRYRLQDEGTP---FQMDPETG-LITVREPLD 312
Query: 94 REKLCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPM-----FPSPVIN 148
E A Y+ + + V L LI++ D NDN P+ FP+
Sbjct: 313 FE---ARRQYSLTVQAM-DRGVPSLTGRAEALIQLL----DVNDNDPVVKFRYFPATSRY 364
Query: 149 ISIPENTLINSRFPIPSATDPDT-GFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLI-- 205
S+ EN + + + + TD D+ NG ++L G ++ + K P L
Sbjct: 365 ASVDENAQVGTVVALLTVTDADSPAANGNISVQILGGNEQRHFEV----QSSKVPNLSLI 420
Query: 206 -VQQNLDREQKDTYVMKIKVEDG-GTPQ------KSSTAILQVTVSDVNDNRPVFKEGQV 257
V LDRE+ +Y + + V D G P +SS A L + V+D+ND+ PVF +
Sbjct: 421 KVASALDRERIPSYNLTVSVSDNYGAPPGAAVQARSSVASLVIFVNDINDHPPVFSQQVY 480
Query: 258 EVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRS 317
V++ E AP G+ V + ATD D G NA +RY V+ F ++ +GL+T S
Sbjct: 481 RVNLSEEAPPGSYVSGISATDGDSGLNANLRYSI---VSGNGLGWFHISEHSGLVTTGSS 537
Query: 318 --LDREETAIHKVTVLASDGSSTP--ARATVTINVTDVNDNPPNIDLRYIISPINGTVYL 373
LDRE + + + A D P + A + + + DVND P P V +
Sbjct: 538 GGLDRELASQIVLNISARDQGVHPKVSYAQLVVTLLDVNDEKPVFS-----QPEGYDVSV 592
Query: 374 SEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP----FHLKAVYDNQYLLETSSLLDY 429
E P T++ ++ +D D NG V ++ F L V L T S LD
Sbjct: 593 VENAPTGTELLMLRATDGDLGDNGTVRFSLQEAETDRRSFRLDPVSGR---LSTISSLDR 649
Query: 430 EGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLT 489
E +S ++A+D G P + A + V L D NDN P+F + EN G Y+T
Sbjct: 650 EEQAFYSLLVLATDLGSPPQSSMARINVSLLDINDNSPVFYPVQYFAHIKENEPGGSYIT 709
Query: 490 TISATDEDSGKNADIVYQLGP-NASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNG 548
T+SATD D G N + Y + + S F ++ ++GV++ DREE+ + + A D G
Sbjct: 710 TVSATDPDLGTNGTVKYSISAGDRSRFQVNAQSGVISTRMALDREEKTAYQLQIVATDGG 769
Query: 549 TPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVT 608
+QA V +TVLD DN P F+ + F V EN+ VG ++ + D N +
Sbjct: 770 NLQSPNQAIVTITVLDTQDNPPVFSQVAYSFVVFENVALGYHVGSVSASTMDLNSNISYL 829
Query: 609 LSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDV 668
++ + F ++ +G + + DRE+QS Y V A+ G + V I V D+
Sbjct: 830 ITTGDQKGMFAINQVTGQLTTANVIDREEQSFYQLKVVASGG---TVTGDTMVNITVKDL 886
Query: 669 NDNSPVVISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRI 728
NDNSP + + + V + G + + AVD D G+N + Y++ N K LF I
Sbjct: 887 NDNSPHFLQAIESVN---VVENWQAGHSIFQAKAVDPDEGVNGMVLYSL-KQNPKNLFAI 942
Query: 729 DPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLVFLYVNDTAGNA 781
+ G I+L P G +++ + SD+G P+ L + V++ +YV+D N+
Sbjct: 943 NEKNGTISL-LGPLDVHAGSYQIEILASDMGVPQ-LSSSVILTVYVHDVNDNS 993
Score = 238 bits (607), Expect = 3e-62
Identities = 178/580 (30%), Positives = 285/580 (49%), Gaps = 34/580 (5%)
Query: 210 LDREQKDT-YVMKI-KVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPV 267
LDREQ Y++ + +E ++ A +++T+ D+NDN PVF +++ + EN
Sbjct: 1696 LDREQGACLYLVDVYAIEKSTAFPRTQRAEVEITLQDINDNPPVFPTDMLDLTVEENIGD 1755
Query: 268 GTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHK 327
G+ ++QL A DAD G+NA + Y + F ++ +G + R LDRE + +
Sbjct: 1756 GSKIMQLTAMDADEGANALVTY----TIISGADDSFRIDPESGDLIATRRLDRERRSKYS 1811
Query: 328 VTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
+ V A DG + + + I V+DVND+ P P+ + + E + +A I
Sbjct: 1812 LLVRADDGLQS-SDMRINITVSDVNDHTPKFS-----RPVY-SFDIPEDTIPGSLVAAIL 1864
Query: 388 VSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGKP 447
+D D+ VNG++ + + + + + + LLDYE + + + A D G
Sbjct: 1865 ATDDDSGVNGEITYIVNEDDEDGIFFLNPITGVFNLTRLLDYEVQQYYILTVRAEDGG-- 1922
Query: 448 SLNQTALVRV--KLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNADIV 505
Q +RV + D NDNPPIF+ S+ EN G + + TD D G N+ +
Sbjct: 1923 --GQFTTIRVYFNILDVNDNPPIFSLNSYSTSLMENLPVGSTVLVFNVTDADDGINSQLT 1980
Query: 506 YQL--GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPP---LQSQAAVIV 560
Y + G + F +D K GVL + DRE Q + V D P S A V +
Sbjct: 1981 YSIASGDSLGQFTVD-KNGVLKVLKALDRESQSFYNLVVQVHDLPQIPASRFTSTAQVSI 2039
Query: 561 TVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADAGENKAVTLSILNDNDN-FV 619
+LD NDN P F ++ EN P + V TD D+G N + ++LN N F
Sbjct: 2040 ILLDVNDNPPTFLSPKLT-YIPENTPIDTVVFKAQATDPDSGPNSYIEYTLLNPLGNKFS 2098
Query: 620 LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVVISPP 679
+ G ++ DRE+ S+YT V ATD GQP SS+ +V + V+D+NDN+P+
Sbjct: 2099 IGTIDGEVRLTGELDREEVSNYTLTVVATDKGQPSLSSSTEVVVMVLDINDNNPIF---- 2154
Query: 680 SNTSFKL-VPLSAIPGSVVAEVFAVDVDTGMNAELKYTIVSGNNKGLFRIDPVTGNITLE 738
+ +K+ + + + G+ + +VFA D D G N +++Y IV+GN FRID VTG IT+
Sbjct: 2155 AQALYKVEINENTLTGTDIIQVFAADGDEGTNGQVRYGIVNGNTNQEFRIDSVTGAITVA 2214
Query: 739 EKPAPTDVGLHRLVVNISDLG-YPKS-LHTLVLVFLYVND 776
+ + L V +D G P++ T+ +V L +ND
Sbjct: 2215 KPLDREKTPTYHLTVQATDRGSTPRTDTSTVSIVLLDIND 2254
Score = 206 bits (524), Expect = 1e-52
Identities = 178/695 (25%), Positives = 317/695 (45%), Gaps = 51/695 (7%)
Query: 33 ELPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRI 92
+ PE IG+ K + + G++ + Y + S++ +++++TGEIF + +I
Sbjct: 2880 DCPELTEIGS--KVTQVFATDPDEGSNGQVFYFIKSQS---EYFRINATTGEIF--NKQI 2932
Query: 93 DREKLCAGASYAEENECFFELEVVILPND-----FFRLIKIKIIVKDTNDNAPMFPSPVI 147
+ + G S N F ++ +D + I + D+NDNAP F
Sbjct: 2933 LKYQNVTGFSNVNINRHSF----IVTSSDRGKPSLISETTVTINIVDSNDNAPQFLKSKY 2988
Query: 148 NISIPENTLINSRF-PIPSATDPDTGFNGVQHYELLNGQSV--FGLDIVETPEGEKWPQL 204
+ +N + ++ + + D D G N Y + N + F LD W +
Sbjct: 2989 FTPVTKNVKVGTKLIRVTAIDDKDFGLNSEVEYFISNDNHLGKFKLD-----NDTGW--I 3041
Query: 205 IVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPEN 264
V +L + + + + +D G P SS A + +TV++ N + P F + + IPE+
Sbjct: 3042 SVASSLISDLNQNFFITVTAKDKGNPPLSSQATVHITVTEENYHTPEFSQSHMSATIPES 3101
Query: 265 APVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETA 324
+G+ V + A D D N I+Y + + +FA+N++TG++T+ ++LD E
Sbjct: 3102 HSIGSIVRTVSARDRDAAMNGLIKYSISSG---NEEGIFAINSSTGILTLAKALDYELCQ 3158
Query: 325 IHKVTVLASDGS--STPARATVTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTK 382
H++T+ A DG + +VT+NV DVNDN P ++ TV E P T
Sbjct: 3159 KHEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPV----FLSDDYFPTVL--ENAPSGTT 3212
Query: 383 IALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
+ + +D D+ N VI + + L + N ++ T LD+E + + + A
Sbjct: 3213 VIHLNATDADSGTNA-VIAYTVQSSDSDLFVIDPNTGVITTQGFLDFETKQSYHLTVKAF 3271
Query: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKNA 502
+ A V ++L+ N+ P F + +SE +G + + A+D D G +
Sbjct: 3272 NVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTIVGEVFASDRDLGTDG 3331
Query: 503 DIVYQLGPNA--SFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQS--QAAV 558
++ Y + N+ F +++KTG + S + DRE++ER V A++ G+ + V
Sbjct: 3332 EVHYLIFGNSRKKGFQINKKTGQIYVSGILDREKEERVSLKVLAKNFGSIRGADIDEVTV 3391
Query: 559 IVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADA---GENKAVTLSILNDN 615
VTVLD ND P FT N + +SE +P + V ++ D+D+ + + N+N
Sbjct: 3392 NVTVLDAND-PPIFTLNIYSVQISEGVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNEN 3450
Query: 616 DNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPPRSSTAKVTINVMDVNDNSPVV 675
F ++P +G I DRE Y V A D G P + +A + + + D+NDN P++
Sbjct: 3451 GAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGTPSATGSASLLVTLEDINDNGPML 3510
Query: 676 ISPPSNTSFKLVPLSAIPGSVVAEVFAVDVDTGMN 710
S V + PG++V + + D D N
Sbjct: 3511 -----TVSEGEVMENKRPGTLVMTLQSTDPDLPPN 3540
Score = 197 bits (502), Expect = 4e-50
Identities = 196/673 (29%), Positives = 301/673 (44%), Gaps = 54/673 (8%)
Query: 128 IKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSV 187
+ I V + N + P F ++ +IPE+ I S SA D D NG+ Y + +G
Sbjct: 3075 VHITVTEENYHTPEFSQSHMSATIPESHSIGSIVRTVSARDRDAAMNGLIKYSISSGNEE 3134
Query: 188 FGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVND 247
G+ + + G L + + LD E + M I DGG ++ + V V DVND
Sbjct: 3135 -GIFAINSSTGI----LTLAKALDYELCQKHEMTISAIDGGWVARTGYCSVTVNVIDVND 3189
Query: 248 NRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNN 307
N PVF + ENAP GT+VI L+ATDAD G+NA I Y V + LF ++
Sbjct: 3190 NSPVFLSDDYFPTVLENAPSGTTVIHLNATDADSGTNAVIAYT----VQSSDSDLFVIDP 3245
Query: 308 TTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYIISPI 367
TG+IT Q LD E + +TV A + + T+N+ N Y+ +
Sbjct: 3246 NTGVITTQGFLDFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTN------EYVPRFV 3299
Query: 368 NGTVY--LSEKDPVNTKIALITVSDKDTDVNGKVICFI---EREVPFHLKAVYDNQYLLE 422
+ Y +SE P T + + SD+D +G+V I R+ F + Y+
Sbjct: 3300 SKLYYFEISEAAPKGTIVGEVFASDRDLGTDGEVHYLIFGNSRKKGFQINKKTGQIYV-- 3357
Query: 423 TSSLLDYEGTKEFSFKIVASDSG--KPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSE 480
S +LD E + S K++A + G + + V V + D ND PPIF + + +SE
Sbjct: 3358 -SGILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDAND-PPIFTLNIYSVQISE 3415
Query: 481 NNRRGLYLTTISATDEDSGKN-ADIVYQLGPNAS--FFDLDRKTGVLTASRVFDREEQER 537
G ++T +SA D DS + + Y +G F ++ +TG +T + DRE
Sbjct: 3416 GVPIGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPI 3475
Query: 538 FIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVT 597
+ +V A D+GTP A+++VT+ D NDN P T + + V EN + V + T
Sbjct: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGPMLTVSEGE--VMENKRPGTLVMTLQST 3533
Query: 598 DADAGENKA----VTLSILNDNDNFVLDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQP 653
D D N+ LS F L +GV+ + DREQ + + V D G P
Sbjct: 3534 DPDLPPNQGPFTYYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVP 3592
Query: 654 PRSSTAKVTINVMDVNDNSPVVISPPSNTSFKLVPL---SAIPGSVVAEVFAVDVDTGMN 710
SST V I V+D NDN P + + ++ + PG ++ V D D
Sbjct: 3593 QMSSTGTVHITVIDQNDN------PSQSRTVEIFVNYYGNLFPGGILGSVKPQDPDV--- 3643
Query: 711 AELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLV 770
+ + ++ LF I G L +P TD G L V +S+ G ++ + + V
Sbjct: 3644 LDSFHCSLTSGVTSLFSIP--GGTCDLNSQPRSTD-GTFDLTV-LSNDGVHSTVTSNIRV 3699
Query: 771 FL--YVNDTAGNA 781
F + N T N+
Sbjct: 3700 FFAGFSNATVDNS 3712
Score = 174 bits (442), Expect = 3e-43
Identities = 160/546 (29%), Positives = 254/546 (46%), Gaps = 44/546 (8%)
Query: 34 LPENVPIGNIPKDLNISHINAATGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRID 93
+PE+ IG+I + ++ +AA L+ +S + + ++SSTG I T + +D
Sbjct: 3098 IPESHSIGSIVRTVSARDRDAAMN---GLIKYSISSGNEEGIFAINSSTG-ILTLAKALD 3153
Query: 94 REKLCAGASYAEENECFFELEVVILPNDFFR---LIKIKIIVKDTNDNAPMFPSPVINIS 150
E LC E+ + + + + + V D NDN+P+F S +
Sbjct: 3154 YE-LCQK----------HEMTISAIDGGWVARTGYCSVTVNVIDVNDNSPVFLSDDYFPT 3202
Query: 151 IPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQNL 210
+ EN + +ATD D+G N V Y + + S L +++ G + Q L
Sbjct: 3203 VLENAPSGTTVIHLNATDADSGTNAVIAYTVQSSDS--DLFVIDPNTGV----ITTQGFL 3256
Query: 211 DREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQVEVHIPENAPVGTS 270
D E K +Y + +K + ++ S A + + + N+ P F I E AP GT
Sbjct: 3257 DFETKQSYHLTVKAFNVPDEERCSFATVNIQLKGTNEYVPRFVSKLYYFEISEAAPKGTI 3316
Query: 271 VIQLHATDADIGSNAEIRY-IFGAQVAPATKRLFALNNTTGLITVQRSLDREETAIHKVT 329
V ++ A+D D+G++ E+ Y IFG + K+ F +N TG I V LDRE+ +
Sbjct: 3317 VGEVFASDRDLGTDGEVHYLIFGN----SRKKGFQINKKTGQIYVSGILDREKEERVSLK 3372
Query: 330 VLASDGSSTPARAT--VTINVTDVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKIALIT 387
VLA + S VT+NVT ++ N P I I S V +SE P+ T + ++
Sbjct: 3373 VLAKNFGSIRGADIDEVTVNVTVLDANDPPIFTLNIYS-----VQISEGVPIGTHVTFVS 3427
Query: 388 VSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVASDSGK 446
D D+ + + FI ++ + ++ LD E ++ ++A DSG
Sbjct: 3428 AFDSDSIPSWSRFSYFIGSGNENGAFSINPQTGQITVTAELDRETLPIYNLSVLAVDSGT 3487
Query: 447 PSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDEDSGKN-ADIV 505
PS +A + V LED NDN P+ V E V EN R G + T+ +TD D N
Sbjct: 3488 PSATGSASLLVTLEDINDNGPMLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFT 3545
Query: 506 YQL---GPNASFFDLDRKTGVLTASRVFDREEQERFIFTVTARDNGTPPLQSQAAVIVTV 562
Y L GP S+F L GVL+ +R DRE+ F +V +D+G P + S V +TV
Sbjct: 3546 YYLLSTGPATSYFSLST-AGVLSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITV 3604
Query: 563 LDENDN 568
+D+NDN
Sbjct: 3605 IDQNDN 3610
Score = 129 bits (324), Expect = 2e-29
Identities = 129/475 (27%), Positives = 206/475 (43%), Gaps = 57/475 (12%)
Query: 42 NIPKDLNISHINAA---TGTSASLVYRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREK-- 96
N P + H+NA +GT+A + Y + S D+ L + +TG + TT +D E
Sbjct: 3206 NAPSGTTVIHLNATDADSGTNAVIAYTVQSS--DSDLFVIDPNTG-VITTQGFLDFETKQ 3262
Query: 97 ----LCAGASYAEENECFFELEVVILPNDFFRLIKIKIIVKDTNDNAPMFPSPV----IN 148
+ +E C F + I +K TN+ P F S + I+
Sbjct: 3263 SYHLTVKAFNVPDEERCSFAT--------------VNIQLKGTNEYVPRFVSKLYYFEIS 3308
Query: 149 ISIPENTLINSRFPIPSATDPDTGFNGVQHYELLNGQSVFGLDIVETPEGEKWPQLIVQQ 208
+ P+ T++ F A+D D G +G HY + G I +K Q+ V
Sbjct: 3309 EAAPKGTIVGEVF----ASDRDLGTDGEVHYLIFGNSRKKGFQI-----NKKTGQIYVSG 3359
Query: 209 NLDREQKDTYVMKIKVEDGGTPQKSST--AILQVTVSDVNDNRPVFKEGQVEVHIPENAP 266
LDRE+++ +K+ ++ G+ + + + VTV D ND P+F V I E P
Sbjct: 3360 ILDREKEERVSLKVLAKNFGSIRGADIDEVTVNVTVLDANDP-PIFTLNIYSVQISEGVP 3418
Query: 267 VGTSVIQLHATDAD-IGSNAEIRYIFGAQVAPATKRLFALNNTTGLITVQRSLDREETAI 325
+GT V + A D+D I S + Y G+ F++N TG ITV LDRE I
Sbjct: 3419 IGTHVTFVSAFDSDSIPSWSRFSYFIGSGNENGA---FSINPQTGQITVTAELDRETLPI 3475
Query: 326 HKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGTVYLSEKDPVNTKI 383
+ ++VLA D + A + ++ VT D+NDN P +++ G V + K P T +
Sbjct: 3476 YNLSVLAVDSGTPSATGSASLLVTLEDINDNGP------MLTVSEGEV-MENKRP-GTLV 3527
Query: 384 ALITVSDKDTDVN-GKVICFIEREVPFHLKAVYDNQYLLETSSLLDYEGTKEFSFKIVAS 442
+ +D D N G ++ P +L T+ +D E +F +V
Sbjct: 3528 MTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGVLSTTREIDREQIADFYLSVVTK 3587
Query: 443 DSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRRGLYLTTISATDED 497
DSG P ++ T V + + D+NDNP I ++ N G L ++ D D
Sbjct: 3588 DSGVPQMSSTGTVHITVIDQNDNPSQSRTVEIFVNYYGNLFPGGILGSVKPQDPD 3642
Score = 57.8 bits (138), Expect = 6e-08
Identities = 81/333 (24%), Positives = 134/333 (40%), Gaps = 54/333 (16%)
Query: 27 IYTIREELPENVPIGNIPKDLNISHINAATGTSASLVYRL---VSKAGDAPLVKVSSSTG 83
IY++ ++ E VPIG +++ ++A S R + + ++ TG
Sbjct: 3408 IYSV--QISEGVPIGT-----HVTFVSAFDSDSIPSWSRFSYFIGSGNENGAFSINPQTG 3460
Query: 84 EIFTTSNRIDREKLCAGASYAEENECFFELEVVILPN---DFFRLIKIKIIVKDTNDNAP 140
+I T+ +DRE L + L V+ + + + + ++D NDN P
Sbjct: 3461 QITVTAE-LDRETLP-----------IYNLSVLAVDSGTPSATGSASLLVTLEDINDNGP 3508
Query: 141 MFPSPVINISIPENTLINSRFPIPSATDPDTGFN-GVQHYELLN---GQSVFGLDIVETP 196
M V + EN + +TDPD N G Y LL+ S F L
Sbjct: 3509 MLT--VSEGEVMENKRPGTLVMTLQSTDPDLPPNQGPFTYYLLSTGPATSYFSLSTAGV- 3565
Query: 197 EGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQ 256
L + +DREQ + + + +D G PQ SST + +TV D NDN + +
Sbjct: 3566 -------LSTTREIDREQIADFYLSVVTKDSGVPQMSSTGTVHITVIDQNDNPSQSRTVE 3618
Query: 257 VEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFAL-NNTTGLITVQ 315
+ V+ N G + + D D+ + F + LF++ T L +
Sbjct: 3619 IFVNYYGNLFPGGILGSVKPQDPDVLDS------FHCSLTSGVTSLFSIPGGTCDLNSQP 3672
Query: 316 RSLDREETAIHKVTVLASDGSSTPARATVTINV 348
RS D +TVL++DG +TVT N+
Sbjct: 3673 RSTD----GTFDLTVLSNDG----VHSTVTSNI 3697
>gi|14589880 protocadherin gamma subfamily A, 3 isoform 1 precursor
[Homo sapiens]
Length = 932
Score = 353 bits (907), Expect = 4e-97
Identities = 226/681 (33%), Positives = 359/681 (52%), Gaps = 42/681 (6%)
Query: 4 RDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLV 63
R LL AL+ L + ++ Y++ EEL + +GNI DL + A
Sbjct: 11 RGLALLCALLGTLCETGS--GQIRYSVSEELDKGSFVGNIANDLGLEPRELAERG----- 63
Query: 64 YRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFF 123
R+VS+ G L ++ +G + T+ RIDRE+LCA C ++ +++ D
Sbjct: 64 VRIVSR-GRTQLFSLNPQSGSL-VTAERIDREELCAQIPL-----CLVKINILV--EDKL 114
Query: 124 RLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLN 183
++ +++I +KD NDNAP FP+ + I I E T+ +RFPI +A DPD G N +Q+Y+L +
Sbjct: 115 KIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKL-S 173
Query: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
F L + EG K+P+L++++ LDRE+K+ + + + DGG P S +QV V
Sbjct: 174 PNDYFSLAVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVL 233
Query: 244 DVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLF 303
D NDN P+F + + V + EN PVGT ++ ++ATD D G NA++ YI + +F
Sbjct: 234 DANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAE-IF 292
Query: 304 ALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYI 363
LN+ +G +++ +SLD E+ +++ + A DG +RA + + V DVNDN P I + +
Sbjct: 293 HLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSL 352
Query: 364 ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLET 423
S + E+ V +IALI V D+D+ NG+V F+ +PF L+ D Y L T
Sbjct: 353 TSSV------PEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVT 406
Query: 424 SSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNR 483
++ LD E E++ + ASD G P L+ + + + D NDNPP F + ENN
Sbjct: 407 ATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNP 466
Query: 484 RGLYLTTISATDEDSGKNADIVYQL-------GPNASFFDLDRKTGVLTASRVFDREEQE 536
RG + +++A D DS NA I Y L P +SF ++ TGVL A R FD E+
Sbjct: 467 RGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFR 526
Query: 537 RFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------PKY 588
VTA D+G PPL S ++ + VLD+NDN+P+ + S + P Y
Sbjct: 527 DLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGY 586
Query: 589 STVGVITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVK 646
V+ V D D+G+N ++ +L ++ F + ++G +++ + + V
Sbjct: 587 LVTKVVAV-DRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 647 ATDGGQPPRSSTAKVTINVMD 667
D GQPP S+T +T+ V D
Sbjct: 646 VQDHGQPPLSATVTLTVAVAD 666
Score = 244 bits (622), Expect = 5e-64
Identities = 195/683 (28%), Positives = 323/683 (47%), Gaps = 68/683 (9%)
Query: 204 LIVQQNLDREQKDTYV------MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQV 257
L+ + +DRE+ + + I VED K +++ + D+NDN P F ++
Sbjct: 84 LVTAERIDREELCAQIPLCLVKINILVED-----KLKIFEVEIEIKDINDNAPNFPTEEL 138
Query: 258 EVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTG-----LI 312
E+ I E GT A D D+G N+ Y +++P A+N+ + +
Sbjct: 139 EIKIGELTVPGTRFPIKTAFDPDVGINSLQNY----KLSPNDYFSLAVNSVSEGAKYPEL 194
Query: 313 TVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGT 370
++R+LDRE+ IH++ ++ASDG + I V D NDNPP + +
Sbjct: 195 VLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPP------MFTQPEYR 248
Query: 371 VYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP------FHLKAVYDNQYLLETS 424
V + E PV T++ + +D D N +V +++ +P FHL +V +L++
Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDK-MPGKIAEIFHLNSVSGEVSILKS- 306
Query: 425 SLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRR 484
LDYE + KI A D P L A + V + D NDN P + SV E
Sbjct: 307 --LDYEDAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTV 362
Query: 485 GLYLTTISATDEDSGKNADI-VYQLG--PNASFFDLDRKTGVLTASRVFDREEQERFIFT 541
G + I D DSG+N + V+ LG P +D+ ++TA+ + DRE+ + +
Sbjct: 363 GREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSL-DREQISEYNIS 421
Query: 542 VTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADA 601
+ A D G+PPL ++ + + V+D NDN P F H + ++ EN P+ +++ +T D D+
Sbjct: 422 LRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDS 481
Query: 602 GENKAVTLSILNDN------DNFV-LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPP 654
N +T ++ D +FV ++ +GV+ + SFD EQ V A+D G PP
Sbjct: 482 NNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPP 541
Query: 655 RSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMN 710
SS + + V+D NDN+P ++ P +T +L P SA PG +V +V AVD D+G N
Sbjct: 542 LSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQN 601
Query: 711 AELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLV 770
A L Y ++ + GLF + TG + D LVV + D G P T+ L
Sbjct: 602 AWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL- 660
Query: 771 FLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVI 830
T A I D++ ++ S++P ++ L +++A+ A + V + +
Sbjct: 661 ------TVAVADRIPDILADL------GSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFV 708
Query: 831 FVTVLVRCRHASRFKAAQRSKQG 853
V + +R R + + Q S G
Sbjct: 709 IVLLALRLRRWHKSRLLQASGGG 731
>gi|14196465 protocadherin gamma subfamily A, 3 isoform 2 precursor
[Homo sapiens]
Length = 829
Score = 353 bits (907), Expect = 4e-97
Identities = 226/681 (33%), Positives = 359/681 (52%), Gaps = 42/681 (6%)
Query: 4 RDFYLLAALIACLRLDSAIAQELIYTIREELPENVPIGNIPKDLNISHINAATGTSASLV 63
R LL AL+ L + ++ Y++ EEL + +GNI DL + A
Sbjct: 11 RGLALLCALLGTLCETGS--GQIRYSVSEELDKGSFVGNIANDLGLEPRELAERG----- 63
Query: 64 YRLVSKAGDAPLVKVSSSTGEIFTTSNRIDREKLCAGASYAEENECFFELEVVILPNDFF 123
R+VS+ G L ++ +G + T+ RIDRE+LCA C ++ +++ D
Sbjct: 64 VRIVSR-GRTQLFSLNPQSGSL-VTAERIDREELCAQIPL-----CLVKINILV--EDKL 114
Query: 124 RLIKIKIIVKDTNDNAPMFPSPVINISIPENTLINSRFPIPSATDPDTGFNGVQHYELLN 183
++ +++I +KD NDNAP FP+ + I I E T+ +RFPI +A DPD G N +Q+Y+L +
Sbjct: 115 KIFEVEIEIKDINDNAPNFPTEELEIKIGELTVPGTRFPIKTAFDPDVGINSLQNYKL-S 173
Query: 184 GQSVFGLDIVETPEGEKWPQLIVQQNLDREQKDTYVMKIKVEDGGTPQKSSTAILQVTVS 243
F L + EG K+P+L++++ LDRE+K+ + + + DGG P S +QV V
Sbjct: 174 PNDYFSLAVNSVSEGAKYPELVLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVL 233
Query: 244 DVNDNRPVFKEGQVEVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLF 303
D NDN P+F + + V + EN PVGT ++ ++ATD D G NA++ YI + +F
Sbjct: 234 DANDNPPMFTQPEYRVSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDKMPGKIAE-IF 292
Query: 304 ALNNTTGLITVQRSLDREETAIHKVTVLASDGSSTPARATVTINVTDVNDNPPNIDLRYI 363
LN+ +G +++ +SLD E+ +++ + A DG +RA + + V DVNDN P I + +
Sbjct: 293 HLNSVSGEVSILKSLDYEDAMFYEIKIEAQDGPGLLSRAKILVTVLDVNDNAPEITITSL 352
Query: 364 ISPINGTVYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVPFHLKAVYDNQYLLET 423
S + E+ V +IALI V D+D+ NG+V F+ +PF L+ D Y L T
Sbjct: 353 TSSV------PEEGTVGREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVT 406
Query: 424 SSLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNR 483
++ LD E E++ + ASD G P L+ + + + D NDNPP F + ENN
Sbjct: 407 ATSLDREQISEYNISLRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNP 466
Query: 484 RGLYLTTISATDEDSGKNADIVYQL-------GPNASFFDLDRKTGVLTASRVFDREEQE 536
RG + +++A D DS NA I Y L P +SF ++ TGVL A R FD E+
Sbjct: 467 RGASIFSVTAQDPDSNNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFR 526
Query: 537 RFIFTVTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENL--------PKY 588
VTA D+G PPL S ++ + VLD+NDN+P+ + S + P Y
Sbjct: 527 DLKLLVTASDSGNPPLSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGY 586
Query: 589 STVGVITVTDADAGENKAVTLSILNDNDN--FVLDPYSGVIKSNVSFDREQQSSYTFDVK 646
V+ V D D+G+N ++ +L ++ F + ++G +++ + + V
Sbjct: 587 LVTKVVAV-DRDSGQNAWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVA 645
Query: 647 ATDGGQPPRSSTAKVTINVMD 667
D GQPP S+T +T+ V D
Sbjct: 646 VQDHGQPPLSATVTLTVAVAD 666
Score = 244 bits (622), Expect = 5e-64
Identities = 195/683 (28%), Positives = 323/683 (47%), Gaps = 68/683 (9%)
Query: 204 LIVQQNLDREQKDTYV------MKIKVEDGGTPQKSSTAILQVTVSDVNDNRPVFKEGQV 257
L+ + +DRE+ + + I VED K +++ + D+NDN P F ++
Sbjct: 84 LVTAERIDREELCAQIPLCLVKINILVED-----KLKIFEVEIEIKDINDNAPNFPTEEL 138
Query: 258 EVHIPENAPVGTSVIQLHATDADIGSNAEIRYIFGAQVAPATKRLFALNNTTG-----LI 312
E+ I E GT A D D+G N+ Y +++P A+N+ + +
Sbjct: 139 EIKIGELTVPGTRFPIKTAFDPDVGINSLQNY----KLSPNDYFSLAVNSVSEGAKYPEL 194
Query: 313 TVQRSLDREETAIHKVTVLASDGSSTPARATVTINVT--DVNDNPPNIDLRYIISPINGT 370
++R+LDRE+ IH++ ++ASDG + I V D NDNPP + +
Sbjct: 195 VLERALDREKKEIHQLVLVASDGGDPVHSGNLHIQVIVLDANDNPP------MFTQPEYR 248
Query: 371 VYLSEKDPVNTKIALITVSDKDTDVNGKVICFIEREVP------FHLKAVYDNQYLLETS 424
V + E PV T++ + +D D N +V +++ +P FHL +V +L++
Sbjct: 249 VSVWENVPVGTRLLTVNATDPDEGFNAQVSYILDK-MPGKIAEIFHLNSVSGEVSILKS- 306
Query: 425 SLLDYEGTKEFSFKIVASDSGKPSLNQTALVRVKLEDENDNPPIFNQPVIELSVSENNRR 484
LDYE + KI A D P L A + V + D NDN P + SV E
Sbjct: 307 --LDYEDAMFYEIKIEAQDG--PGLLSRAKILVTVLDVNDNAPEITITSLTSSVPEEGTV 362
Query: 485 GLYLTTISATDEDSGKNADI-VYQLG--PNASFFDLDRKTGVLTASRVFDREEQERFIFT 541
G + I D DSG+N + V+ LG P +D+ ++TA+ + DRE+ + +
Sbjct: 363 GREIALIDVHDRDSGQNGQVEVFVLGNLPFKLEKSIDQYYRLVTATSL-DREQISEYNIS 421
Query: 542 VTARDNGTPPLQSQAAVIVTVLDENDNSPKFTHNHFQFFVSENLPKYSTVGVITVTDADA 601
+ A D G+PPL ++ + + V+D NDN P F H + ++ EN P+ +++ +T D D+
Sbjct: 422 LRASDGGSPPLSTETHITLHVIDINDNPPTFPHLSYSAYIPENNPRGASIFSVTAQDPDS 481
Query: 602 GENKAVTLSILNDN------DNFV-LDPYSGVIKSNVSFDREQQSSYTFDVKATDGGQPP 654
N +T ++ D +FV ++ +GV+ + SFD EQ V A+D G PP
Sbjct: 482 NNNARITYALTEDTLQGAPLSSFVSINSNTGVLYALRSFDYEQFRDLKLLVTASDSGNPP 541
Query: 655 RSSTAKVTINVMDVNDNSPVVISPP----SNTSFKLVPLSAIPGSVVAEVFAVDVDTGMN 710
SS + + V+D NDN+P ++ P +T +L P SA PG +V +V AVD D+G N
Sbjct: 542 LSSNVSLNLFVLDQNDNAPEILYPALPTDGSTGVELAPRSAEPGYLVTKVVAVDRDSGQN 601
Query: 711 AELKYTIVSGNNKGLFRIDPVTGNITLEEKPAPTDVGLHRLVVNISDLGYPKSLHTLVLV 770
A L Y ++ + GLF + TG + D LVV + D G P T+ L
Sbjct: 602 AWLSYRLLKASEPGLFSVGLHTGEVRTARALLDRDALKQSLVVAVQDHGQPPLSATVTL- 660
Query: 771 FLYVNDTAGNASYIYDLIRRTMETPLDRNIGDSSQPYQNEDYLTIMIAIIAGAMVVIVVI 830
T A I D++ ++ S++P ++ L +++A+ A + V + +
Sbjct: 661 ------TVAVADRIPDILADL------GSLEPSAKPNDSDLTLYLVVAVAAVSCVFLAFV 708
Query: 831 FVTVLVRCRHASRFKAAQRSKQG 853
V + +R R + + Q S G
Sbjct: 709 IVLLALRLRRWHKSRLLQASGGG 731
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.380
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 47,838,755
Number of Sequences: 37866
Number of extensions: 2346425
Number of successful extensions: 15276
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 195
Number of HSP's successfully gapped in prelim test: 43
Number of HSP's that attempted gapping in prelim test: 5999
Number of HSP's gapped (non-prelim): 1047
length of query: 1203
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1089
effective length of database: 13,930,794
effective search space: 15170634666
effective search space used: 15170634666
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.