Search of human proteins with 92859871

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
         (496 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]            1031   0.0  
gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]            471   e-133
gi|5174517 SMAD family member 7 [Homo sapiens]                        373   e-103
gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo sapi...   142   9e-34
gi|5174519 SMAD family member 9 isoform b [Homo sapiens]              140   3e-33
gi|5174513 mothers against decapentaplegic homolog 3 isoform 1 [...   139   5e-33
gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]   131   1e-30
gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]    131   1e-30
gi|223029442 mothers against decapentaplegic homolog 3 isoform 3...   128   1e-29
gi|223029440 mothers against decapentaplegic homolog 3 isoform 2...   111   2e-24
gi|223029444 mothers against decapentaplegic homolog 3 isoform 4...   100   5e-21
gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]    99   9e-21
gi|187828357 SMAD family member 9 isoform a [Homo sapiens]             97   3e-20
gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]         95   1e-19
gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]         95   1e-19
gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]         95   1e-19
gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]              95   2e-19
gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]               95   2e-19
gi|239751736 PREDICTED: hypothetical protein [Homo sapiens]            48   2e-05
gi|239746237 PREDICTED: hypothetical protein XP_002343710 [Homo ...    48   2e-05
gi|171543895 ataxin 2 [Homo sapiens]                                   47   5e-05
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     45   1e-04
gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]            45   2e-04
gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo ...    45   2e-04
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      44   3e-04
gi|153070260 myristoylated alanine-rich protein kinase C substra...    44   3e-04
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    44   3e-04
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    44   3e-04
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    44   3e-04
gi|4885407 hyperpolarization activated cyclic nucleotide-gated p...    43   6e-04

>gi|92859871 SMAD family member 6 isoform 1 [Homo sapiens]
          Length = 496

 Score = 1031 bits (2667), Expect = 0.0
 Identities = 496/496 (100%), Positives = 496/496 (100%)

Query: 1   MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV 60
           MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV
Sbjct: 1   MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV 60

Query: 61  RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
           RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD
Sbjct: 61  RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120

Query: 121 CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL 180
           CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL
Sbjct: 121 CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL 180

Query: 181 KRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVE 240
           KRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVE
Sbjct: 181 KRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQPAPPQLLLGRLFRWPDLQHAVE 240

Query: 241 LKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSY 300
           LKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSY
Sbjct: 241 LKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSY 300

Query: 301 TETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDL 360
           TETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDL
Sbjct: 301 TETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAVYDQAVSIFYDL 360

Query: 361 PQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP 420
           PQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP
Sbjct: 361 PQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP 420

Query: 421 GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF 480
           GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF
Sbjct: 421 GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAADGPYDPNSVRISFAKGWGPCYSRQF 480

Query: 481 ITSCPCWLEILLNNPR 496
           ITSCPCWLEILLNNPR
Sbjct: 481 ITSCPCWLEILLNNPR 496


>gi|218749837 SMAD family member 6 isoform 2 [Homo sapiens]
          Length = 235

 Score =  471 bits (1213), Expect = e-133
 Identities = 223/224 (99%), Positives = 224/224 (100%)

Query: 273 ESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWC 332
           +SPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWC
Sbjct: 12  KSPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWC 71

Query: 333 SVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGIL 392
           SVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGIL
Sbjct: 72  SVAYWEHRTRVGRLYAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGIL 131

Query: 393 LSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAPEP 452
           LSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAPEP
Sbjct: 132 LSKEPDGVWAYNRGEHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERSGLQHAPEP 191

Query: 453 DAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR 496
           DAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR
Sbjct: 192 DAADGPYDPNSVRISFAKGWGPCYSRQFITSCPCWLEILLNNPR 235


>gi|5174517 SMAD family member 7 [Homo sapiens]
          Length = 426

 Score =  373 bits (958), Expect = e-103
 Identities = 227/509 (44%), Positives = 282/509 (55%), Gaps = 99/509 (19%)

Query: 1   MFRSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEV 60
           MFR+KRS LVRRLWRSR            GG  +E+G+             GGG G  E+
Sbjct: 1   MFRTKRSALVRRLWRSRAP----------GGEDEEEGA-------------GGGGGGGEL 37

Query: 61  RPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
           R                                   G GA  S    A  GGPG      
Sbjct: 38  R-----------------------------------GEGATDSRAHGAGGGGPG------ 56

Query: 121 CETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVTYSLL 180
                CCL      A        P AGA    AGG             E +LK +T+S+L
Sbjct: 57  --RAGCCLGKAVRGAKGHHHPHPPAAGAGA--AGGA------------EADLKALTHSVL 100

Query: 181 KRLKERSLDTLLEAVESRGGVPGGCVLVP-RADLRLG------GQPAPPQ------LLLG 227
           K+LKER L+ LL+AVESRGG    C+L+P R D RLG       QPA P       LLL 
Sbjct: 101 KKLKERQLELLLQAVESRGGTRTACLLLPGRLDCRLGPGAPAGAQPAQPPSSYSLPLLLC 160

Query: 228 RLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDE 287
           ++FRWPDL+H+ E+K LC C S+    +   VCCNP+H SRLC  ESPPPPYSR  P D 
Sbjct: 161 KVFRWPDLRHSSEVKRLCCCESYGKI-NPELVCCNPHHLSRLCELESPPPPYSRY-PMDF 218

Query: 288 YKPL-DLSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPSHWCSVAYWEHRTRVGRL 346
            KP  D  D+  S  ET  TN L  APG  SD+ +  +    SHWC VAYWE +TRVGRL
Sbjct: 219 LKPTADCPDAVPSSAETGGTNYL--APGGLSDSQLLLEPGDRSHWCVVAYWEEKTRVGRL 276

Query: 347 YAVYDQAVSIFYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRG 406
           Y V + ++ IFYDLPQG+GFCLGQLN + +S+ V++ RSKIG GI L++E DGVW YNR 
Sbjct: 277 YCVQEPSLDIFYDLPQGNGFCLGQLNSDNKSQLVQKVRSKIGCGIQLTREVDGVWVYNRS 336

Query: 407 EHPIFVNSPTLDAPGGRALVVRKVPPGYSIKVFDFERS-GLQHAPEPDAADGPYDPNSVR 465
            +PIF+ S TLD P  R L+V KV PG+SIK FD+E++  LQ   + +    P+   +V+
Sbjct: 337 SYPIFIKSATLDNPDSRTLLVHKVFPGFSIKAFDYEKAYSLQRPNDHEFMQQPWTGFTVQ 396

Query: 466 ISFAKGWGPCYSRQFITSCPCWLEILLNN 494
           ISF KGWG CY+RQFI+SCPCWLE++ N+
Sbjct: 397 ISFVKGWGQCYTRQFISSCPCWLEVIFNS 425


>gi|209693426 Sma- and Mad-related protein 2 isoform 2 [Homo
           sapiens]
          Length = 437

 Score =  142 bits (357), Expect = 9e-34
 Identities = 118/396 (29%), Positives = 178/396 (44%), Gaps = 61/396 (15%)

Query: 153 AGGGRSREARSRLLLLEQELKTVTYSLLKRLKERS-LDTLLEAVESRGGVPGGCVLVPRA 211
           AGGG            E+  +    SL+K+LK+   LD L +A+ ++      CV +PR+
Sbjct: 28  AGGGEQNGQE------EKWCEKAVKSLVKKLKKTGRLDELEKAITTQN-CNTKCVTIPRS 80

Query: 212 ---DLRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSR 268
               L++  +   P ++  RL+RWPDL    ELK +  C  +A       VC NPYH+ R
Sbjct: 81  LDGRLQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC-EYAFNLKKDEVCVNPYHYQR 139

Query: 269 LCGPESPP-------------PP---YSRLSPRDEYKPLDLSDSTLSYTET--------- 303
           +  P  PP             PP   Y+   P +   P  +   +    ET         
Sbjct: 140 VETPVLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISED 199

Query: 304 ------EATNSLIT-APGEFSDASMSP----------DATKPSHWCSVAYWEHRTRVGRL 346
                 +   S+ T +P E S  ++SP            ++P+ WCS+AY+E   RVG  
Sbjct: 200 GETSDQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGET 259

Query: 347 YAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYN 404
           +     ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A  
Sbjct: 260 FHASQPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAEC 319

Query: 405 RGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN 462
             +  IFV SP  +   G     V K+PPG ++K+F + E + L         +  Y   
Sbjct: 320 LSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLT 379

Query: 463 ---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
              ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 380 RMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 415


>gi|5174519 SMAD family member 9 isoform b [Homo sapiens]
          Length = 430

 Score =  140 bits (352), Expect = 3e-33
 Identities = 119/374 (31%), Positives = 169/374 (45%), Gaps = 61/374 (16%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           SL+K+LK++  ++D L  A+ S  G P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 40  SLVKKLKKKKGAMDELERAL-SCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 98

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---------------- 276
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP                
Sbjct: 99  PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQLSLL 157

Query: 277 --------------------------PPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLI 310
                                     PP S L P   +     S  T SY  +  + S  
Sbjct: 158 AKFRSASLHSEPLMPHNATYPDSFQQPPCSALPPSPSHA-FSQSPCTASYPHSPGSPSEP 216

Query: 311 TAPGEFSDASMSPDA-TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-F 366
            +P + SD    P    +P HWCSVAY+E   RVG  +    ++V I  F D       F
Sbjct: 217 ESPYQHSD--FRPVCYEEPQHWCSVAYYELNNRVGETFQASSRSVLIDGFTDPSNNRNRF 274

Query: 367 CLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RAL 425
           CLG L+   R+ ++  TR  IG G+ L      V+A    +  IFV S   +   G    
Sbjct: 275 CLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVSDSSIFVQSRNCNYQHGFHPA 334

Query: 426 VVRKVPPGYSIKVFDFER-SGLQHAPEPDAADGPYDPN---SVRISFAKGWGPCYSRQFI 481
            V K+P G S+KVF+ +  + L         +  Y+     ++R+SF KGWG  Y RQ +
Sbjct: 335 TVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKMCTIRMSFVKGWGAEYHRQDV 394

Query: 482 TSCPCWLEILLNNP 495
           TS PCW+EI L+ P
Sbjct: 395 TSTPCWIEIHLHGP 408


>gi|5174513 mothers against decapentaplegic homolog 3 isoform 1
           [Homo sapiens]
          Length = 425

 Score =  139 bits (351), Expect = 5e-33
 Identities = 113/371 (30%), Positives = 174/371 (46%), Gaps = 57/371 (15%)

Query: 178 SLLKRLKERS-LDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRWP 233
           SL+K+LK+   LD L +A+ ++  V   C+ +PR+    L++  +   P ++  RL+RWP
Sbjct: 37  SLVKKLKKTGQLDELEKAITTQN-VNTKCITIPRSLDGRLQVSHRKGLPHVIYCRLWRWP 95

Query: 234 DLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPRDEYKP 290
           DL    EL+ +  C  FA       VC NPYH+ R+  P  PP   P ++ +    E+ P
Sbjct: 96  DLHSHHELRAMELCE-FAFNMKKDEVCVNPYHYQRVETPVLPPVLVPRHTEIPA--EFPP 152

Query: 291 LD-----LSDSTLSYTETEATNSLITAP--------GEFSDASM-----------SPDAT 326
           LD     + ++T      E  +++   P        GE SD  M           SP+  
Sbjct: 153 LDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPM 212

Query: 327 KPSH---------------WCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLG 369
            P+H               WCS++Y+E   RVG  +     ++++  F D      FCLG
Sbjct: 213 SPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLG 272

Query: 370 QLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVR 428
            L+   R+ +V  TR  IG G+ L      V+A    +  IFV SP  +   G     V 
Sbjct: 273 LLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVC 332

Query: 429 KVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSC 484
           K+PPG ++K+F+ +      A   +   +  Y      ++R+SF KGWG  Y RQ +TS 
Sbjct: 333 KIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTST 392

Query: 485 PCWLEILLNNP 495
           PCW+E+ LN P
Sbjct: 393 PCWIELHLNGP 403


>gi|51173730 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  131 bits (330), Expect = 1e-30
 Identities = 100/332 (30%), Positives = 149/332 (44%), Gaps = 50/332 (15%)

Query: 213 LRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP 272
           L++  +   P ++  RL+RWPDL    ELK +  C  +A       VC NPYH+ R+  P
Sbjct: 115 LQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC-EYAFNLKKDEVCVNPYHYQRVETP 173

Query: 273 ESPP-------------PP---YSRLSPRDEYKPLDLSDSTLSYTET------------- 303
             PP             PP   Y+   P +   P  +   +    ET             
Sbjct: 174 VLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETS 233

Query: 304 --EATNSLIT-APGEFSDASMSP----------DATKPSHWCSVAYWEHRTRVGRLYAVY 350
             +   S+ T +P E S  ++SP            ++P+ WCS+AY+E   RVG  +   
Sbjct: 234 DQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHAS 293

Query: 351 DQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEH 408
             ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A    + 
Sbjct: 294 QPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDS 353

Query: 409 PIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN---S 463
            IFV SP  +   G     V K+PPG ++K+F + E + L         +  Y      +
Sbjct: 354 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 413

Query: 464 VRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
           +R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 414 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 445


>gi|5174511 Sma- and Mad-related protein 2 isoform 1 [Homo sapiens]
          Length = 467

 Score =  131 bits (330), Expect = 1e-30
 Identities = 100/332 (30%), Positives = 149/332 (44%), Gaps = 50/332 (15%)

Query: 213 LRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP 272
           L++  +   P ++  RL+RWPDL    ELK +  C  +A       VC NPYH+ R+  P
Sbjct: 115 LQVSHRKGLPHVIYCRLWRWPDLHSHHELKAIENC-EYAFNLKKDEVCVNPYHYQRVETP 173

Query: 273 ESPP-------------PP---YSRLSPRDEYKPLDLSDSTLSYTET------------- 303
             PP             PP   Y+   P +   P  +   +    ET             
Sbjct: 174 VLPPVLVPRHTEILTELPPLDDYTHSIPENTNFPAGIEPQSNYIPETPPPGYISEDGETS 233

Query: 304 --EATNSLIT-APGEFSDASMSP----------DATKPSHWCSVAYWEHRTRVGRLYAVY 350
             +   S+ T +P E S  ++SP            ++P+ WCS+AY+E   RVG  +   
Sbjct: 234 DQQLNQSMDTGSPAELSPTTLSPVNHSLDLQPVTYSEPAFWCSIAYYELNQRVGETFHAS 293

Query: 351 DQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEH 408
             ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A    + 
Sbjct: 294 QPSLTVDGFTDPSNSERFCLGLLSNVNRNATVEMTRRHIGRGVRLYYIGGEVFAECLSDS 353

Query: 409 PIFVNSPTLDAP-GGRALVVRKVPPGYSIKVF-DFERSGLQHAPEPDAADGPYDPN---S 463
            IFV SP  +   G     V K+PPG ++K+F + E + L         +  Y      +
Sbjct: 354 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 413

Query: 464 VRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
           +R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 414 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 445


>gi|223029442 mothers against decapentaplegic homolog 3 isoform 3
           [Homo sapiens]
          Length = 381

 Score =  128 bits (322), Expect = 1e-29
 Identities = 100/332 (30%), Positives = 151/332 (45%), Gaps = 52/332 (15%)

Query: 213 LRLGGQPAPPQLLLGRLFRWPDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGP 272
           L++  +   P ++  RL+RWPDL    EL+ +  C  FA       VC NPYH+ R+  P
Sbjct: 31  LQVSHRKGLPHVIYCRLWRWPDLHSHHELRAMELCE-FAFNMKKDEVCVNPYHYQRVETP 89

Query: 273 ESPP---PPYSRLSPRDEYKPLD-----LSDSTLSYTETEATNSLITAP--------GEF 316
             PP   P ++ +    E+ PLD     + ++T      E  +++   P        GE 
Sbjct: 90  VLPPVLVPRHTEIPA--EFPPLDDYSHSIPENTNFPAGIEPQSNIPETPPPGYLSEDGET 147

Query: 317 SDASM-----------SPDATKPSH---------------WCSVAYWEHRTRVGRLYAVY 350
           SD  M           SP+   P+H               WCS++Y+E   RVG  +   
Sbjct: 148 SDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISYYELNQRVGETFHAS 207

Query: 351 DQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEH 408
             ++++  F D      FCLG L+   R+ +V  TR  IG G+ L      V+A    + 
Sbjct: 208 QPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLYYIGGEVFAECLSDS 267

Query: 409 PIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDPN---S 463
            IFV SP  +   G     V K+PPG ++K+F+ +      A   +   +  Y      +
Sbjct: 268 AIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVNQGFEAVYQLTRMCT 327

Query: 464 VRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
           +R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 328 IRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 359


>gi|223029440 mothers against decapentaplegic homolog 3 isoform 2
           [Homo sapiens]
          Length = 320

 Score =  111 bits (277), Expect = 2e-24
 Identities = 86/286 (30%), Positives = 129/286 (45%), Gaps = 51/286 (17%)

Query: 259 VCCNPYHFSRLCGPESPP---PPYSRLSPRDEYKPLD-----LSDSTLSYTETEATNSLI 310
           VC NPYH+ R+  P  PP   P ++ +    E+ PLD     + ++T      E  +++ 
Sbjct: 15  VCVNPYHYQRVETPVLPPVLVPRHTEIPA--EFPPLDDYSHSIPENTNFPAGIEPQSNIP 72

Query: 311 TAP--------GEFSDASM-----------SPDATKPSH---------------WCSVAY 336
             P        GE SD  M           SP+   P+H               WCS++Y
Sbjct: 73  ETPPPGYLSEDGETSDHQMNHSMDAGSPNLSPNPMSPAHNNLDLQPVTYCEPAFWCSISY 132

Query: 337 WEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTRSKIGFGILLS 394
           +E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR  IG G+ L 
Sbjct: 133 YELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTRRHIGRGVRLY 192

Query: 395 KEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFERSGLQHAPEPD 453
                V+A    +  IFV SP  +   G     V K+PPG ++K+F+ +      A   +
Sbjct: 193 YIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQEFAALLAQSVN 252

Query: 454 AA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
              +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 253 QGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 298


>gi|223029444 mothers against decapentaplegic homolog 3 isoform 4
           [Homo sapiens]
          Length = 230

 Score = 99.8 bits (247), Expect = 5e-21
 Identities = 60/176 (34%), Positives = 91/176 (51%), Gaps = 7/176 (3%)

Query: 327 KPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSGFCLGQLNLEQRSESVRRTR 384
           +P+ WCS++Y+E   RVG  +     ++++  F D      FCLG L+   R+ +V  TR
Sbjct: 33  EPAFWCSISYYELNQRVGETFHASQPSMTVDGFTDPSNSERFCLGLLSNVNRNAAVELTR 92

Query: 385 SKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLDAP-GGRALVVRKVPPGYSIKVFDFER 443
             IG G+ L      V+A    +  IFV SP  +   G     V K+PPG ++K+F+ + 
Sbjct: 93  RHIGRGVRLYYIGGEVFAECLSDSAIFVQSPNCNQRYGWHPATVCKIPPGCNLKIFNNQE 152

Query: 444 SGLQHAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
                A   +   +  Y      ++R+SF KGWG  Y RQ +TS PCW+E+ LN P
Sbjct: 153 FAALLAQSVNQGFEAVYQLTRMCTIRMSFVKGWGAEYRRQTVTSTPCWIELHLNGP 208


>gi|4885457 mothers against decapentaplegic homolog 4 [Homo sapiens]
          Length = 552

 Score = 99.0 bits (245), Expect = 9e-21
 Identities = 70/211 (33%), Positives = 93/211 (44%), Gaps = 45/211 (21%)

Query: 328 PSHWCSVAYWEHRTRVGRLYAVYDQA----VSIFYDLPQGSGFCLGQLNLEQRSESVRRT 383
           P +WCS+AY+E   +VG  + V        V  + D   G  FCLGQL+   R+E++ R 
Sbjct: 320 PEYWCSIAYFEMDVQVGETFKVPSSCPIVTVDGYVDPSGGDRFCLGQLSNVHRTEAIERA 379

Query: 384 RSKIGFGILLSKEPDG-VWAYNRGEHPIFVNSPTLDAPGGRAL--VVRKVPPGYSIKVFD 440
           R  IG G+ L  + +G VW     +H +FV S  LD   GRA    V K+ P   IKVFD
Sbjct: 380 RLHIGKGVQLECKGEGDVWVRCLSDHAVFVQSYYLDREAGRAPGDAVHKIYPSAYIKVFD 439

Query: 441 FERSGLQ---------------------HAPEPDAADGPYDPNS---------------- 463
             +   Q                     + P P +  G     S                
Sbjct: 440 LRQCHRQMQQQAATAQAAAAAQAAAVAGNIPGPGSVGGIAPAISLSAAAGIGVDDLRRLC 499

Query: 464 -VRISFAKGWGPCYSRQFITSCPCWLEILLN 493
            +R+SF KGWGP Y RQ I   PCW+EI L+
Sbjct: 500 ILRMSFVKGWGPDYPRQSIKETPCWIEIHLH 530



 Score = 67.8 bits (164), Expect = 2e-11
 Identities = 41/106 (38%), Positives = 61/106 (57%), Gaps = 9/106 (8%)

Query: 173 KTVTYSLLKRLKERS--LDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLG 227
           K    SL+K+LKE+   LD+L+ A+ + G  P  CV + R     L++ G+   P ++  
Sbjct: 37  KRAIESLVKKLKEKKDELDSLITAITTNGAHPSKCVTIQRTLDGRLQVAGRKGFPHVIYA 96

Query: 228 RLFRWPDLQHAVELKPLCGC-HSFAAAADGPTVCCNPYHFSRLCGP 272
           RL+RWPDL H  ELK +  C ++F    D  +VC NPYH+ R+  P
Sbjct: 97  RLWRWPDL-HKNELKHVKYCQYAFDLKCD--SVCVNPYHYERVVSP 139


>gi|187828357 SMAD family member 9 isoform a [Homo sapiens]
          Length = 467

 Score = 97.4 bits (241), Expect = 3e-20
 Identities = 84/274 (30%), Positives = 124/274 (45%), Gaps = 30/274 (10%)

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPY--SRLSPRDEYKP 290
           P   HA    P     S+  +   P+   +PY  S     ++PP PY  +  S     +P
Sbjct: 191 PSPSHAFSQSPCTA--SYPHSPGSPSEPESPYQHS----VDTPPLPYHATEASETQSGQP 244

Query: 291 LDLSDSTLSYTETEATNSLITAP-GEFSDASMSPDATKPSHWCSVAYWEHRTRVGRLYAV 349
           +D          T   + +++ P G+F          +P HWCSVAY+E   RVG  +  
Sbjct: 245 VDA---------TADRHVVLSIPNGDFRPVCYE----EPQHWCSVAYYELNNRVGETFQA 291

Query: 350 YDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRG 406
             ++V I  F D       FCLG L+   R+ ++  TR  IG G+ L      V+A    
Sbjct: 292 SSRSVLIDGFTDPSNNRNRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECVS 351

Query: 407 EHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFER-SGLQHAPEPDAADGPYDPN-- 462
           +  IFV S   +   G     V K+P G S+KVF+ +  + L         +  Y+    
Sbjct: 352 DSSIFVQSRNCNYQHGFHPATVCKIPSGCSLKVFNNQLFAQLLAQSVHHGFEVVYELTKM 411

Query: 463 -SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
            ++R+SF KGWG  Y RQ +TS PCW+EI L+ P
Sbjct: 412 CTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 445



 Score = 67.4 bits (163), Expect = 3e-11
 Identities = 44/116 (37%), Positives = 66/116 (56%), Gaps = 10/116 (8%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           SL+K+LK++  ++D L  A+ S  G P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 40  SLVKKLKKKKGAMDELERAL-SCPGQPSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 98

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPR 285
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP   P +S  +P+
Sbjct: 99  PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYRRVETPVLPPVLVPRHSEYNPQ 153


>gi|47778931 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 24/262 (9%)

Query: 243 PLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTE 302
           P    +  + A+ GP    +P+       P +  PP  ++  +D  +P+D S+       
Sbjct: 197 PASSTYPNSPASSGPG---SPFQLPADTPPPAYMPPDDQMG-QDNSQPMDTSN------- 245

Query: 303 TEATNSLITAPGEFSDASMSPDA-TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYD 359
               N +       S   + P A  +P HWCS+ Y+E   RVG  +     +V +  F D
Sbjct: 246 ----NMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD 301

Query: 360 LPQG-SGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLD 418
                S FCLG L+   R+ ++  TR  IG G+ L      V+A    +  IFV S   +
Sbjct: 302 PSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCN 361

Query: 419 APGG-RALVVRKVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDPN---SVRISFAKGWG 473
              G     V K+P   S+K+F+ +      A   +   +  Y+     ++R+SF KGWG
Sbjct: 362 FHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWG 421

Query: 474 PCYSRQFITSCPCWLEILLNNP 495
             Y RQ +TS PCW+EI L+ P
Sbjct: 422 AEYHRQDVTSTPCWIEIHLHGP 443



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 8/157 (5%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           +L+K+LK++  +++ L +A+ S G  P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQ-PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 95

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLD 292
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP    R +  +    L 
Sbjct: 96  PDLQSHHELKPLDIC-EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLL 154

Query: 293 LSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPS 329
           +    LS+ E     +  T P  F   + +P    P+
Sbjct: 155 VQFRNLSHNEPHMPQN-ATFPDSFHQPNNTPFPLSPN 190


>gi|47778929 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 24/262 (9%)

Query: 243 PLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTE 302
           P    +  + A+ GP    +P+       P +  PP  ++  +D  +P+D S+       
Sbjct: 197 PASSTYPNSPASSGPG---SPFQLPADTPPPAYMPPDDQMG-QDNSQPMDTSN------- 245

Query: 303 TEATNSLITAPGEFSDASMSPDA-TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYD 359
               N +       S   + P A  +P HWCS+ Y+E   RVG  +     +V +  F D
Sbjct: 246 ----NMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD 301

Query: 360 LPQG-SGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLD 418
                S FCLG L+   R+ ++  TR  IG G+ L      V+A    +  IFV S   +
Sbjct: 302 PSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCN 361

Query: 419 APGG-RALVVRKVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDPN---SVRISFAKGWG 473
              G     V K+P   S+K+F+ +      A   +   +  Y+     ++R+SF KGWG
Sbjct: 362 FHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWG 421

Query: 474 PCYSRQFITSCPCWLEILLNNP 495
             Y RQ +TS PCW+EI L+ P
Sbjct: 422 AEYHRQDVTSTPCWIEIHLHGP 443



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 8/157 (5%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           +L+K+LK++  +++ L +A+ S G  P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQ-PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 95

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLD 292
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP    R +  +    L 
Sbjct: 96  PDLQSHHELKPLDIC-EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLL 154

Query: 293 LSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPS 329
           +    LS+ E     +  T P  F   + +P    P+
Sbjct: 155 VQFRNLSHNEPHMPQN-ATFPDSFHQPNNTPFPLSPN 190


>gi|47778925 SMAD, mothers against DPP homolog 5 [Homo sapiens]
          Length = 465

 Score = 95.1 bits (235), Expect = 1e-19
 Identities = 76/262 (29%), Positives = 118/262 (45%), Gaps = 24/262 (9%)

Query: 243 PLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLDLSDSTLSYTE 302
           P    +  + A+ GP    +P+       P +  PP  ++  +D  +P+D S+       
Sbjct: 197 PASSTYPNSPASSGPG---SPFQLPADTPPPAYMPPDDQMG-QDNSQPMDTSN------- 245

Query: 303 TEATNSLITAPGEFSDASMSPDA-TKPSHWCSVAYWEHRTRVGRLYAVYDQAVSI--FYD 359
               N +       S   + P A  +P HWCS+ Y+E   RVG  +     +V +  F D
Sbjct: 246 ----NMIPQIMPSISSRDVQPVAYEEPKHWCSIVYYELNNRVGEAFHASSTSVLVDGFTD 301

Query: 360 LPQG-SGFCLGQLNLEQRSESVRRTRSKIGFGILLSKEPDGVWAYNRGEHPIFVNSPTLD 418
                S FCLG L+   R+ ++  TR  IG G+ L      V+A    +  IFV S   +
Sbjct: 302 PSNNKSRFCLGLLSNVNRNSTIENTRRHIGKGVHLYYVGGEVYAECLSDSSIFVQSRNCN 361

Query: 419 APGG-RALVVRKVPPGYSIKVFDFERSGLQHAPEPDAA-DGPYDPN---SVRISFAKGWG 473
              G     V K+P   S+K+F+ +      A   +   +  Y+     ++R+SF KGWG
Sbjct: 362 FHHGFHPTTVCKIPSSCSLKIFNNQEFAQLLAQSVNHGFEAVYELTKMCTIRMSFVKGWG 421

Query: 474 PCYSRQFITSCPCWLEILLNNP 495
             Y RQ +TS PCW+EI L+ P
Sbjct: 422 AEYHRQDVTSTPCWIEIHLHGP 443



 Score = 68.2 bits (165), Expect = 2e-11
 Identities = 49/157 (31%), Positives = 79/157 (50%), Gaps = 8/157 (5%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           +L+K+LK++  +++ L +A+ S G  P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 37  ALVKKLKKKKGAMEELEKALSSPGQ-PSKCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 95

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPPPPYSRLSPRDEYKPLD 292
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP    R +  +    L 
Sbjct: 96  PDLQSHHELKPLDIC-EFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHNEFNPQHSLL 154

Query: 293 LSDSTLSYTETEATNSLITAPGEFSDASMSPDATKPS 329
           +    LS+ E     +  T P  F   + +P    P+
Sbjct: 155 VQFRNLSHNEPHMPQN-ATFPDSFHQPNNTPFPLSPN 190


>gi|51173727 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 74/232 (31%), Positives = 107/232 (46%), Gaps = 18/232 (7%)

Query: 273 ESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDA-TKPSHW 331
           ++PPP Y  L P D   P+    S    T   A       P E +   +   A  +P HW
Sbjct: 221 DTPPPAY--LPPED---PMTQDGSQPMDTNMMAP----PLPSEINRGDVQAVAYEEPKHW 271

Query: 332 CSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIG 388
           CS+ Y+E   RVG  +     +V +  F D       FCLG L+   R+ ++  TR  IG
Sbjct: 272 CSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIG 331

Query: 389 FGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFERSGLQ 447
            G+ L      V+A    +  IFV S   +   G     V K+P G S+K+F+ +     
Sbjct: 332 KGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQL 391

Query: 448 HAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
            A   +   +  Y+     ++R+SF KGWG  Y RQ +TS PCW+EI L+ P
Sbjct: 392 LAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 443



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 10/116 (8%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           +L+K+LK++  +++ L +A+ S  G P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 36  ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 94

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPR 285
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP   P +S  +P+
Sbjct: 95  PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQ 149


>gi|5174509 Sma- and Mad-related protein 1 [Homo sapiens]
          Length = 465

 Score = 94.7 bits (234), Expect = 2e-19
 Identities = 74/232 (31%), Positives = 107/232 (46%), Gaps = 18/232 (7%)

Query: 273 ESPPPPYSRLSPRDEYKPLDLSDSTLSYTETEATNSLITAPGEFSDASMSPDA-TKPSHW 331
           ++PPP Y  L P D   P+    S    T   A       P E +   +   A  +P HW
Sbjct: 221 DTPPPAY--LPPED---PMTQDGSQPMDTNMMAP----PLPSEINRGDVQAVAYEEPKHW 271

Query: 332 CSVAYWEHRTRVGRLYAVYDQAVSI--FYDLPQGSG-FCLGQLNLEQRSESVRRTRSKIG 388
           CS+ Y+E   RVG  +     +V +  F D       FCLG L+   R+ ++  TR  IG
Sbjct: 272 CSIVYYELNNRVGEAFHASSTSVLVDGFTDPSNNKNRFCLGLLSNVNRNSTIENTRRHIG 331

Query: 389 FGILLSKEPDGVWAYNRGEHPIFVNSPTLDAPGG-RALVVRKVPPGYSIKVFDFERSGLQ 447
            G+ L      V+A    +  IFV S   +   G     V K+P G S+K+F+ +     
Sbjct: 332 KGVHLYYVGGEVYAECLSDSSIFVQSRNCNYHHGFHPTTVCKIPSGCSLKIFNNQEFAQL 391

Query: 448 HAPEPDAA-DGPYDPN---SVRISFAKGWGPCYSRQFITSCPCWLEILLNNP 495
            A   +   +  Y+     ++R+SF KGWG  Y RQ +TS PCW+EI L+ P
Sbjct: 392 LAQSVNHGFETVYELTKMCTIRMSFVKGWGAEYHRQDVTSTPCWIEIHLHGP 443



 Score = 67.0 bits (162), Expect = 4e-11
 Identities = 42/116 (36%), Positives = 67/116 (57%), Gaps = 10/116 (8%)

Query: 178 SLLKRLKER--SLDTLLEAVESRGGVPGGCVLVPRA---DLRLGGQPAPPQLLLGRLFRW 232
           +L+K+LK++  +++ L +A+ S  G P  CV +PR+    L++  +   P ++  R++RW
Sbjct: 36  ALVKKLKKKKGAMEELEKAL-SCPGQPSNCVTIPRSLDGRLQVSHRKGLPHVIYCRVWRW 94

Query: 233 PDLQHAVELKPLCGCHSFAAAADGPTVCCNPYHFSRLCGPESPP---PPYSRLSPR 285
           PDLQ   ELKPL  C  F   +    VC NPYH+ R+  P  PP   P +S  +P+
Sbjct: 95  PDLQSHHELKPL-ECCEFPFGSKQKEVCINPYHYKRVESPVLPPVLVPRHSEYNPQ 149


>gi|239751736 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 261

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 74/279 (26%), Positives = 96/279 (34%), Gaps = 75/279 (26%)

Query: 11  RRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGG-CGRSEVRPVAPRRPR 69
           R  WR+R    R+E   GGG          SRA P P A  GG   GRS   P + +  R
Sbjct: 16  RGSWRTR---SRQEARPGGG----------SRARPGPGAGPGGEVLGRSSSTPASSKASR 62

Query: 70  DAVGQRGA-------------------------QGAGRRRRAGGP------PRPMSEPGA 98
            A  ++                            GAG R + GGP      P   +E  A
Sbjct: 63  TAQMRKATSSGSVPVLSVLWSSVSGSDGKAVRLNGAGPRPKRGGPWCGAKRPSQSAERSA 122

Query: 99  GAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRS 158
            + +       PG   W  E       C   S + +AG  RD    ++G   +PA     
Sbjct: 123 ASSTPPEKTCAPGMKPWCGE------RCSSSSRKPSAGGGRDGGVAVSGRD-QPA----- 170

Query: 159 REARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQ 218
             AR+ L    Q L      LL  +     D +L   E  G  PG             G 
Sbjct: 171 --ARTMLAARRQRLGPGRRELL--MARSFPDPILARPELHGRWPGP-----------AGT 215

Query: 219 PAPP---QLLLGRLFRWPDLQHAVELKPLCGCHSFAAAA 254
           PAPP   + L   L+RW +L       P CG  + A  A
Sbjct: 216 PAPPGASRELRTSLWRWVNLGVWSATAPACGRGTRAGTA 254


>gi|239746237 PREDICTED: hypothetical protein XP_002343710 [Homo
           sapiens]
          Length = 261

 Score = 47.8 bits (112), Expect = 2e-05
 Identities = 74/279 (26%), Positives = 96/279 (34%), Gaps = 75/279 (26%)

Query: 11  RRLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGG-CGRSEVRPVAPRRPR 69
           R  WR+R    R+E   GGG          SRA P P A  GG   GRS   P + +  R
Sbjct: 16  RGSWRTR---SRQEARPGGG----------SRARPGPGAGPGGEVLGRSSSTPASSKASR 62

Query: 70  DAVGQRGA-------------------------QGAGRRRRAGGP------PRPMSEPGA 98
            A  ++                            GAG R + GGP      P   +E  A
Sbjct: 63  TAQMRKATSSGSVPVLSVLWSSVSGSDGKAVRLNGAGPRPKRGGPWCGAKRPSQSAERSA 122

Query: 99  GAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRS 158
            + +       PG   W  E       C   S + +AG  RD    ++G   +PA     
Sbjct: 123 ASSTPPEKTCAPGMKPWCGE------RCSSSSRKPSAGGGRDGGVAVSGRD-QPA----- 170

Query: 159 REARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLGGQ 218
             AR+ L    Q L      LL  +     D +L   E  G  PG             G 
Sbjct: 171 --ARTMLAARRQRLGPGRRELL--MARSFPDPILARPELHGRWPGP-----------AGT 215

Query: 219 PAPP---QLLLGRLFRWPDLQHAVELKPLCGCHSFAAAA 254
           PAPP   + L   L+RW +L       P CG  + A  A
Sbjct: 216 PAPPGASRELRTSLWRWVNLGVWSATAPACGRGTRAGTA 254


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 46.6 bits (109), Expect = 5e-05
 Identities = 48/146 (32%), Positives = 54/146 (36%), Gaps = 28/146 (19%)

Query: 14  WRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVG 73
           WRS   P R    SG GGGG   G   S A P P      G G    R  +P    D  G
Sbjct: 28  WRSLQRPARR---SGRGGGGAAPGPYPSAAPPPP------GPGPPPSRQSSPPSASDCFG 78

Query: 74  QRGAQGA----GRRR--RAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPE------SDC 121
             G  G     G RR    GGPPRP           LL +A PG P   P       +  
Sbjct: 79  SNGNGGGAFRPGSRRLLGLGGPPRPFV-------VLLLPLASPGAPPAAPTRASPLGARA 131

Query: 122 ETVTCCLFSERDAAGAPRDASDPLAG 147
                 +   R A G PR A +P+ G
Sbjct: 132 SPPRSGVSLARPAPGCPRPACEPVYG 157


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 32/94 (34%), Positives = 34/94 (36%), Gaps = 4/94 (4%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRP---RDAVGQRGAQGAG 81
           G  G  G   E GS G +  P P   EG      E     P  P   R + G RG  GA 
Sbjct: 352 GSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGAD 411

Query: 82  RRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            R    GPP      G AG      D   PG PG
Sbjct: 412 GRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPG 445



 Score = 40.0 bits (92), Expect = 0.005
 Identities = 39/140 (27%), Positives = 44/140 (31%), Gaps = 33/140 (23%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--------GGCGRSEVR---------- 61
           PD   G  G  G     G  G +  P P   +G        G  G+   R          
Sbjct: 524 PDGNNGAQGPPGPQGVQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPG 583

Query: 62  PVAPRRPRDAVGQRGAQGAGR---RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPE 118
           P  PR  R   G+ GA G       R   GPP P    G       +  A P GP  LP 
Sbjct: 584 PAGPRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLP- 642

Query: 119 SDCETVTCCLFSERDAAGAP 138
                       ER AAG P
Sbjct: 643 -----------GERGAAGIP 651



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 31/105 (29%), Positives = 36/105 (34%), Gaps = 12/105 (11%)

Query: 15  RSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQ 74
           R  V P    G +G  G   + G+ G R    P+   G       V P  P       G 
Sbjct: 714 RGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENG------VVGPTGPVGAAGPAGP 767

Query: 75  RGAQGAGRRRRAGGPPRPMSEPGAGA-----GSSLLDVAEPGGPG 114
            G  G    R  GGPP     PGA       G S +    PG PG
Sbjct: 768 NGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGIS-GPPGPPG 811



 Score = 36.2 bits (82), Expect = 0.071
 Identities = 24/90 (26%), Positives = 32/90 (35%), Gaps = 5/90 (5%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G  G  G     G+ G   EP P   +G    + E     P+ P    G+ G +G     
Sbjct: 328 GIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEA 387

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
            + GPP P    G+     L     PG  G
Sbjct: 388 GSAGPPGPPGLRGSPGSRGL-----PGADG 412



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 26/94 (27%), Positives = 30/94 (31%), Gaps = 18/94 (19%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAE------------------PAPRAREGGGCGRSEVRPVA 64
           E G +G  GG  E G  G R E                  P P    G         P  
Sbjct: 644 ERGAAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAG 703

Query: 65  PRRPRDAVGQRGAQGAGRRRRAGGPPRPMSEPGA 98
           P  PR + G+RG  G        GP     +PGA
Sbjct: 704 PAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGA 737



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 29/101 (28%), Positives = 33/101 (32%), Gaps = 11/101 (10%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCG----RSEVRPVAPRRPRDAVG 73
           E G +G  G     GS G R E  P    G     G  G    + E     P+     VG
Sbjct: 695 EAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGERGAKGPKGENGVVG 754

Query: 74  QRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
             G  GA       GPP P    G G    +     PG  G
Sbjct: 755 PTGPVGAAGPAGPNGPPGPAGSRGDGGPPGM--TGFPGAAG 793



 Score = 33.1 bits (74), Expect = 0.60
 Identities = 26/92 (28%), Positives = 32/92 (34%), Gaps = 4/92 (4%)

Query: 24  EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
           +G +G  G     G  G R  P P    G    R  V    P   +   G +G  G+   
Sbjct: 309 KGAAGLPGVAGAPGLPGPRGIPGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGP 368

Query: 84  RRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
           +   GPP P  E G  G          PG PG
Sbjct: 369 Q---GPPGPSGEEGKRGPNGEAGSAGPPGPPG 397



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 31/100 (31%), Positives = 35/100 (35%), Gaps = 15/100 (15%)

Query: 24  EGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCGR----SEVRPVAPRRPRDAVGQRGA 77
           +G  G  G     G  G+R  P  R R G  G  G       V PV P  P  + G  G 
Sbjct: 198 KGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGPAGPIGSAGPPGF 257

Query: 78  QGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLP 117
            GA         P P  E GA   +     A P G   LP
Sbjct: 258 PGA---------PGPKGEIGAVGNAGPAGPAGPRGEVGLP 288



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 30/107 (28%), Positives = 35/107 (32%), Gaps = 16/107 (14%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRR---PRDAVGQ------R 75
           G  G  G   + G  G+     P    G    R EV P  P     P  A GQ      R
Sbjct: 682 GAPGPAGATGDRGEAGAAGPAGPAGPRGSPGERGEVGPAGPNGFAGPAGAAGQPGAKGER 741

Query: 76  GAQGAGRRRRAGGPPRPMSEPG-------AGAGSSLLDVAEPGGPGW 115
           GA+G        GP  P+   G        G   S  D   PG  G+
Sbjct: 742 GAKGPKGENGVVGPTGPVGAAGPAGPNGPPGPAGSRGDGGPPGMTGF 788



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 33/106 (31%), Positives = 37/106 (34%), Gaps = 10/106 (9%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRSEVRPVAPRRPRDAVGQ 74
           P  EEG  G  G   E GS G    P  R   G     G  GR+ V  + P   R A G 
Sbjct: 374 PSGEEGKRGPNG---EAGSAGPPGPPGLRGSPGSRGLPGADGRAGV--MGPPGSRGASGP 428

Query: 75  RGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
            G +G        G P  M   G       +  A   GP  LP  D
Sbjct: 429 AGVRGPNGDAGRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGID 474



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 30/102 (29%), Positives = 35/102 (34%), Gaps = 7/102 (6%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSR---AEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRG 76
           P  E G  G  G     G +GSR     P P   +G       V    P  P    G+RG
Sbjct: 587 PRGERGPPGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERG 646

Query: 77  AQGAGRRRRAGGPPRPMSEPG----AGAGSSLLDVAEPGGPG 114
           A G    +   G P    E G     GA  +   V  PG  G
Sbjct: 647 AAGIPGGKGEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAG 688



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 32/101 (31%), Positives = 33/101 (32%), Gaps = 14/101 (13%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA-- 80
           E G  G  G     G  G    P P    G       V PV P  P  + G  G  GA  
Sbjct: 206 ENGTPGQTGARGLPGERGRVGAPGPAGARGSD---GSVGPVGPAGPIGSAGPPGFPGAPG 262

Query: 81  -----GRRRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                G    AG  GP  P  E G    S    V  PG PG
Sbjct: 263 PKGEIGAVGNAGPAGPAGPRGEVGLPGLSG--PVGPPGNPG 301



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 28/98 (28%), Positives = 33/98 (33%), Gaps = 4/98 (4%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGG---CGRSEVRPVA-PRRPRDAVGQR 75
           P  E G  G  G   EDG  G    P P    G G     + + + V     P   +G R
Sbjct: 40  PRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPGPMGLMGPR 99

Query: 76  GAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
           G  GA       G   P  EPG    +       P GP
Sbjct: 100 GPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGARGPAGP 137



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 3/73 (4%)

Query: 21   DREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGA 77
            D + G  G  G     G +G+   P P    G  G  G R E  P  P  P  AVG RG 
Sbjct: 939  DGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGPVGPAGAVGPRGP 998

Query: 78   QGAGRRRRAGGPP 90
             G    R   G P
Sbjct: 999  SGPQGIRGDKGEP 1011



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 25/93 (26%), Positives = 30/93 (32%)

Query: 21  DREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA 80
           D  +G  G  G   E G+ G    P      G    R  V    P   R + G  G  G 
Sbjct: 186 DGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLPGERGRVGAPGPAGARGSDGSVGPVGP 245

Query: 81  GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
                + GPP     PG       +  A P GP
Sbjct: 246 AGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGP 278



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 38/139 (27%), Positives = 44/139 (31%), Gaps = 18/139 (12%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
           PD  +G  G  G     G  G    P  R   G   G+ E      R     +G  G  G
Sbjct: 617 PDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKGEPGLR---GEIGNPGRDG 673

Query: 80  AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAG--A 137
           A     A G P P    G    +     A P GP   P             ER   G   
Sbjct: 674 ARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGPRGSP------------GERGEVGPAG 721

Query: 138 PRDASDPLAGAALEPAGGG 156
           P   + P AGAA +P   G
Sbjct: 722 PNGFAGP-AGAAGQPGAKG 739



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 29/93 (31%), Positives = 31/93 (33%), Gaps = 9/93 (9%)

Query: 30  GGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGP 89
           G  GD  G  G R  P P  R+G         P  P  P    G   AQ  G+    G  
Sbjct: 33  GPAGDR-GPRGERGPPGPPGRDGEDGPTGPPGPPGPPGPPGLGGNFAAQYDGKGVGLGPG 91

Query: 90  PR----PMSEPGA----GAGSSLLDVAEPGGPG 114
           P     P   PGA    G         EPG PG
Sbjct: 92  PMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPG 124



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 26/95 (27%), Positives = 31/95 (32%), Gaps = 14/95 (14%)

Query: 21  DREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA 80
           D   G  G  G   E G++G      P    G    +               G RGA G 
Sbjct: 474 DGRPGPIGPAGARGEPGNIGFPGPKGPTGDPGKNGDKGHA---------GLAGARGAPGP 524

Query: 81  GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGW 115
                A GPP P    G G G    +   PG PG+
Sbjct: 525 DGNNGAQGPPGPQGVQG-GKG----EQGPPGPPGF 554



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 27/98 (27%), Positives = 34/98 (34%), Gaps = 15/98 (15%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREG--------GGCGRSEVRPVAPRRPRDAVGQRG 76
           G +G  G   E G+ G    P P+   G        G  G   +  VA      AVG+ G
Sbjct: 841 GFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGVA-----GAVGEPG 895

Query: 77  AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
             G      A GPP  +  PG        +    G PG
Sbjct: 896 PLGIAGPPGARGPPGAVGSPGVNGAPG--EAGRDGNPG 931



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 31/100 (31%), Positives = 35/100 (35%), Gaps = 19/100 (19%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA-GRR 83
           G  G  G     G  G+  EP P    G         P   R P  AVG  G  GA G  
Sbjct: 874 GLPGSRGERGLPGVAGAVGEPGPLGIAG---------PPGARGPPGAVGSPGVNGAPGEA 924

Query: 84  RRAG-----GPPRPMSEPG----AGAGSSLLDVAEPGGPG 114
            R G     GPP    +PG     G   ++  V   G PG
Sbjct: 925 GRDGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPG 964



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/99 (28%), Positives = 30/99 (30%), Gaps = 7/99 (7%)

Query: 21   DREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA 80
            D   G  G  G   + G  G R  P      G         PV P       G+ G  G 
Sbjct: 927  DGNPGNDGPPGRDGQPGHKGERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGETGPSGP 986

Query: 81   GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPG--GPGWLP 117
                 A GP  P    G        D  EPG  GP  LP
Sbjct: 987  VGPAGAVGPRGPSGPQGIRG-----DKGEPGEKGPRGLP 1020


>gi|239751535 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 255

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/105 (38%), Positives = 44/105 (41%), Gaps = 19/105 (18%)

Query: 12  RLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA------- 64
           RL   R  P     G  G GGG    + G  A  A  AR+  G GRS    VA       
Sbjct: 145 RLCPQRASPGCSSPGVRGPGGGASPRARGGNAAAALAARQAAGGGRSRSAFVAGRDAALA 204

Query: 65  ----PRRPRDAVGQRGAQ---GAGRR--RRAGGPPRPMSEPGAGA 100
               PRRPR A  +RG +   GAG R   R  GPPR    P  GA
Sbjct: 205 CAQLPRRPRGAGARRGMRRRLGAGERPAPRPRGPPR---APARGA 246



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 46/150 (30%), Positives = 57/150 (38%), Gaps = 26/150 (17%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G   GGGGGD  G       P  RAR GGGC          R  +DA      +G   + 
Sbjct: 37  GPRAGGGGGDAGGG----GAPVRRAR-GGGCW--------ARAYQDARCFGRGEGGDLQV 83

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFS-----ERDAAGA-- 137
            +G    P +E  A A S+      P GPG+ P       T   FS      R +A A  
Sbjct: 84  SSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLP-RPFTSASFSNQTRLRRRSASALP 142

Query: 138 -----PRDASDPLAGAALEPAGGGRSREAR 162
                P+ AS   +   +   GGG S  AR
Sbjct: 143 APRLCPQRASPGCSSPGVRGPGGGASPRAR 172



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 49/153 (32%), Positives = 54/153 (35%), Gaps = 16/153 (10%)

Query: 28  GGGGGGDEDGSLGSRAEPAPR----AREGGGCGRSEVRP-VAPRRPRDAVGQRGA-QGAG 81
           G G GGD   S G  A P       AR   G       P   PR PR       + Q   
Sbjct: 74  GRGEGGDLQVSSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLPRPFTSASFSNQTRL 133

Query: 82  RRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAG---- 136
           RRR A   P P   P  A  G S   V  PGG G  P +        L + + A G    
Sbjct: 134 RRRSASALPAPRLCPQRASPGCSSPGVRGPGG-GASPRARGGNAAAALAARQAAGGGRSR 192

Query: 137 ----APRDASDPLAGAALEPAGGGRSREARSRL 165
               A RDA+   A     P G G  R  R RL
Sbjct: 193 SAFVAGRDAALACAQLPRRPRGAGARRGMRRRL 225


>gi|239746046 PREDICTED: hypothetical protein XP_002343643 [Homo
           sapiens]
          Length = 255

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 40/105 (38%), Positives = 44/105 (41%), Gaps = 19/105 (18%)

Query: 12  RLWRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA------- 64
           RL   R  P     G  G GGG    + G  A  A  AR+  G GRS    VA       
Sbjct: 145 RLCPQRASPGCSSPGVRGPGGGASPRARGGNAAAALAARQAAGGGRSRSAFVAGRDAALA 204

Query: 65  ----PRRPRDAVGQRGAQ---GAGRR--RRAGGPPRPMSEPGAGA 100
               PRRPR A  +RG +   GAG R   R  GPPR    P  GA
Sbjct: 205 CAQLPRRPRGAGARRGMRRRLGAGERPAPRPRGPPR---APARGA 246



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 46/150 (30%), Positives = 57/150 (38%), Gaps = 26/150 (17%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G   GGGGGD  G       P  RAR GGGC          R  +DA      +G   + 
Sbjct: 37  GPRAGGGGGDAGGG----GAPVRRAR-GGGCW--------ARAYQDARCFGRGEGGDLQV 83

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFS-----ERDAAGA-- 137
            +G    P +E  A A S+      P GPG+ P       T   FS      R +A A  
Sbjct: 84  SSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLP-RPFTSASFSNQTRLRRRSASALP 142

Query: 138 -----PRDASDPLAGAALEPAGGGRSREAR 162
                P+ AS   +   +   GGG S  AR
Sbjct: 143 APRLCPQRASPGCSSPGVRGPGGGASPRAR 172



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 49/153 (32%), Positives = 54/153 (35%), Gaps = 16/153 (10%)

Query: 28  GGGGGGDEDGSLGSRAEPAPR----AREGGGCGRSEVRP-VAPRRPRDAVGQRGA-QGAG 81
           G G GGD   S G  A P       AR   G       P   PR PR       + Q   
Sbjct: 74  GRGEGGDLQVSSGPGAAPPAEFRASARSAQGSRDVPAGPGFPPRLPRPFTSASFSNQTRL 133

Query: 82  RRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAG---- 136
           RRR A   P P   P  A  G S   V  PGG G  P +        L + + A G    
Sbjct: 134 RRRSASALPAPRLCPQRASPGCSSPGVRGPGG-GASPRARGGNAAAALAARQAAGGGRSR 192

Query: 137 ----APRDASDPLAGAALEPAGGGRSREARSRL 165
               A RDA+   A     P G G  R  R RL
Sbjct: 193 SAFVAGRDAALACAQLPRRPRGAGARRGMRRRL 225


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 21/148 (14%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCG-RSEVRPVAPRRPRDAVGQRGAQ 78
           G  G  G    DG+ GS  +P P    G     G  G + EV P        A GQRG  
Sbjct: 312 GLPGAAGARGNDGARGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEP 371

Query: 79  GAGRRRRAGGPPRPMSEPGAGAGSSLLDVAE-PGGPGWLPESDCETVTCCLFSERDAAG- 136
           G      A GPP P    G+  G   +  A  PG PG             L   R   G 
Sbjct: 372 GPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPG-------------LMGARGPPGP 418

Query: 137 APRDASDPLAGAALEPAGGGRSREARSR 164
           A  + +  L G A EP   G   E   R
Sbjct: 419 AGANGAPGLRGGAGEPGKNGAKGEPGPR 446



 Score = 41.2 bits (95), Expect = 0.002
 Identities = 27/83 (32%), Positives = 35/83 (42%), Gaps = 6/83 (7%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRS-EVRPVAPRRPRDAVGQRGAQ 78
            G  G  G   + G++GS     PR   G     G  G S    P+ P  PR   G+RG++
Sbjct: 1116 GAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSE 1175

Query: 79   GAGRRRRAGGPPRPMSEPGAGAG 101
            G+       GPP P   PG   G
Sbjct: 1176 GSPGHPGQPGPPGPPGAPGPCCG 1198



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 38/135 (28%), Positives = 44/135 (32%), Gaps = 28/135 (20%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           + G  GG GG    G  G   E  P+   G         P  P   +   G  G QG   
Sbjct: 592 KNGERGGPGGPGPQGPPGKNGETGPQGPPG---------PTGPGGDKGDTGPPGPQGLQG 642

Query: 83  RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDAS 142
               GGPP    +PG        D   PG PG                 +  AGAP +  
Sbjct: 643 LPGTGGPPGENGKPGEPGPKG--DAGAPGAPG----------------GKGDAGAPGERG 684

Query: 143 DP-LAGAALEPAGGG 156
            P LAGA     G G
Sbjct: 685 PPGLAGAPGLRGGAG 699



 Score = 40.4 bits (93), Expect = 0.004
 Identities = 34/101 (33%), Positives = 38/101 (37%), Gaps = 17/101 (16%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEP----APRAREGGGCGRSEVRPVA--PRRPRDAVG 73
           P  + G  G  GG  + G+ G R  P    AP  R G G    E    A  P  P  A G
Sbjct: 661 PKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAG 720

Query: 74  QRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
             G QG    R   G P P  + G           EPGGPG
Sbjct: 721 TPGLQGMPGERGGLGSPGPKGDKG-----------EPGGPG 750



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 26/94 (27%), Positives = 30/94 (31%), Gaps = 6/94 (6%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
            P    G +G  G   E G  G    P P    G         P  PR  +   G+RGA G
Sbjct: 1051 PPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAP------GPQGPRGDKGETGERGAAG 1104

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
                R   G P     PG       +    P GP
Sbjct: 1105 IKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGP 1138



 Score = 38.1 bits (87), Expect = 0.019
 Identities = 30/99 (30%), Positives = 35/99 (35%), Gaps = 2/99 (2%)

Query: 21  DREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGA 80
           D ++G  G  G     G+ G R  P  R   G      E  P   R      G RGA G 
Sbjct: 464 DGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE 523

Query: 81  GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPES 119
             R    G P     PG+  G       +PG PG   ES
Sbjct: 524 PGRDGVPGGPGMRGMPGSPGGPG--SDGKPGPPGSQGES 560



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 38/119 (31%), Positives = 45/119 (37%), Gaps = 26/119 (21%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-------GGCGRSEVRPVAPRRP---- 68
           P    G  G  GG  E G  G++ EP PR   G        G    + +  +P  P    
Sbjct: 418 PAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANG 477

Query: 69  -RDAVGQRGAQG----------AGRRRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGPG 114
              A G+RGA G           G +  AG  G P P    GA AG    D   PGGPG
Sbjct: 478 LPGAAGERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGA-AGEPGRD-GVPGGPG 534



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 33/98 (33%), Positives = 36/98 (36%), Gaps = 8/98 (8%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRP------RDAVGQRG 76
           E G  G  G   EDG  GS  EP      G    R       P  P      +   G+RG
Sbjct: 451 EAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGPAGPNGIPGEKGPAGERG 510

Query: 77  AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
           A G    R A G P     PG G G   +    PGGPG
Sbjct: 511 APGPAGPRGAAGEPGRDGVPG-GPGMRGMP-GSPGGPG 546



 Score = 37.0 bits (84), Expect = 0.041
 Identities = 29/100 (29%), Positives = 35/100 (35%), Gaps = 6/100 (6%)

Query: 21  DREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG- 79
           D   GG G  G     G  GS  +P P   +G         P  PR     +G  G +G 
Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGN 586

Query: 80  ---AGRRRRAGGP--PRPMSEPGAGAGSSLLDVAEPGGPG 114
               G+    GGP  P P   PG    +       P GPG
Sbjct: 587 DGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 32/97 (32%), Positives = 38/97 (39%), Gaps = 13/97 (13%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCGRSEVRPVAPRRPRDAVGQRGAQG--- 79
           G +G  GG  E G+ G + E  P    G  GG G     P  P  P+   G+RG+ G   
Sbjct: 816 GQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG-----PAGPPGPQGVKGERGSPGGPG 870

Query: 80  -AGRRRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGP 113
            AG     G  GPP     PG    S       P GP
Sbjct: 871 AAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGP 907



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 39/143 (27%), Positives = 48/143 (33%), Gaps = 8/143 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
            +G +G  G     G+ G    P P    G    R    P     PR + G +G +G   +
Sbjct: 923  KGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGLAGPPGMPGPRGSPGPQGVKGESGK 982

Query: 84   RRAG------GPPRPMSEPG-AGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAG 136
              A       GPP P   PG AG          PG  G LP  D          E  + G
Sbjct: 983  PGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGSDG-LPGRDGSPGGKGDRGENGSPG 1041

Query: 137  APRDASDPLAGAALEPAGGGRSR 159
            AP     P     + PAG    R
Sbjct: 1042 APGAPGHPGPPGPVGPAGKSGDR 1064



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 30/93 (32%), Positives = 36/93 (38%), Gaps = 7/93 (7%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           E+G +G  G   E+G  G    P P    G    R   RP  P     A G RG  GA  
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERG--RPGLP----GAAGARGNDGARG 327

Query: 83  RRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
                GPP P    G  G+  +  +V   G PG
Sbjct: 328 SDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPG 360



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 29/95 (30%), Positives = 36/95 (37%), Gaps = 8/95 (8%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCGRSEVRPVAPRRPRDAVGQRGAQGA 80
            E G +G  G     G+ G+   P P  ++G  G  G     P  PR P    G  G  G 
Sbjct: 1099 ERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPG-----PAGPRGPVGPSGPPGKDGT 1153

Query: 81   GRRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
                   GPP P    G  G+  S     +PG PG
Sbjct: 1154 SGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPG 1188



 Score = 35.0 bits (79), Expect = 0.16
 Identities = 32/108 (29%), Positives = 34/108 (31%), Gaps = 22/108 (20%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
           P  + G  G GG     G  G R  P  R   G         P  P     A GQ G  G
Sbjct: 772 PAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG---------PPGPAGFPGAPGQNGEPG 822

Query: 80  AGRRRRA------GGPPRPMSEPGA-------GAGSSLLDVAEPGGPG 114
               R A      GGPP     PG        G      +   PGGPG
Sbjct: 823 GKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPG 870



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 16/136 (11%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           G  GG G     G  G+   P  +   G  GG G        P+  +   G  GA G   
Sbjct: 702 GPEGGKGAAGPPGPPGAAGTPGLQGMPGERGGLGSP-----GPKGDKGEPGGPGADGVPG 756

Query: 83  RRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDA 141
           +    GP  P+  PG AG      +   PG PG                ER   G P  A
Sbjct: 757 KDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSP-------GERGETGPPGPA 809

Query: 142 SDPLA-GAALEPAGGG 156
             P A G   EP G G
Sbjct: 810 GFPGAPGQNGEPGGKG 825



 Score = 32.7 bits (73), Expect = 0.78
 Identities = 38/124 (30%), Positives = 45/124 (36%), Gaps = 33/124 (26%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRSEVR--------PVAPRRPR 69
            + G SG  G     G  GSR  P P+   G     G  G + ++        P AP  P 
Sbjct: 1063 DRGESGPAGPAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPG 1122

Query: 70   DAVGQRGAQG----AGRRRRAG-----------GPPRPMSEPG----AGAGSSLLDVAEP 110
             A GQ+GA G    AG R   G           G P P+  PG     G   S      P
Sbjct: 1123 PA-GQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHP 1181

Query: 111  GGPG 114
            G PG
Sbjct: 1182 GQPG 1185



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 41/150 (27%), Positives = 48/150 (32%), Gaps = 23/150 (15%)

Query: 24  EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
           +G  G  G    +G+ G R EP P+   G                +  +G  G  GA   
Sbjct: 350 KGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGL 409

Query: 84  RRAGGPPRPMSEPGA-----GAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAP 138
             A GPP P    GA     GAG       EPG  G   E            ER  AG P
Sbjct: 410 MGARGPPGPAGANGAPGLRGGAG-------EPGKNGAKGEPGPR-------GERGEAGIP 455

Query: 139 ----RDASDPLAGAALEPAGGGRSREARSR 164
                   D   G+  EP   G    A  R
Sbjct: 456 GVPGAKGEDGKDGSPGEPGANGLPGAAGER 485



 Score = 31.2 bits (69), Expect = 2.3
 Identities = 20/74 (27%), Positives = 23/74 (31%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
            +G  G  G    DGS G + +       G         P  P  P    G RG  G    
Sbjct: 1013 DGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGP 1072

Query: 84   RRAGGPPRPMSEPG 97
              A GP      PG
Sbjct: 1073 AGAPGPAGSRGAPG 1086



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 29/107 (27%), Positives = 40/107 (37%), Gaps = 9/107 (8%)

Query: 45  PAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-------AGRRRRAGGPPRPMSEPG 97
           P P    G  C      P AP RP +  G +G +G        GR    G P +P S PG
Sbjct: 75  PNPEIPFGECCAVCPQPPTAPTRPPNGQGPQGPKGDPGPPGIPGRNGDPGIPGQPGS-PG 133

Query: 98  AGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDP 144
           +     + +    G   + P+ D   V   + +    AG P  A  P
Sbjct: 134 SPGPPGICESCPTGPQNYSPQYDSYDVKSGV-AVGGLAGYPGPAGPP 179



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 25/92 (27%), Positives = 32/92 (34%), Gaps = 12/92 (13%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAP--RRPRDAVGQRGAQGAGR 82
           G +G  G     GS G    P P    G         P +P    P+   GQ G +G+  
Sbjct: 885 GSNGNPGPPGPSGSPGKDGPPGPAGNTGA--------PGSPGVSGPKGDAGQPGEKGSPG 936

Query: 83  RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
            +   G P P+   G      L     PG PG
Sbjct: 937 AQGPPGAPGPLGIAGITGARGL--AGPPGMPG 966



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 28/98 (28%), Positives = 32/98 (32%), Gaps = 11/98 (11%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCGRS-EVRPVAPRRPRDAVGQRG 76
           P   +G  G  GG    G  G+R  P P    G  G  G S       P  P    G  G
Sbjct: 856 PQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPG 915

Query: 77  AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
           + G    +   G P     PGA           PG PG
Sbjct: 916 SPGVSGPKGDAGQPGEKGSPGA--------QGPPGAPG 945



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 29/87 (33%), Positives = 31/87 (35%), Gaps = 6/87 (6%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSE----VRPVAPRRPRDAVGQR 75
            P    G +G  G    DG+ GS   P      GG   R E      P AP  P    G  
Sbjct: 997  PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHP-GPPGPV 1055

Query: 76   GAQGAGRRRRAGGPPRPMSEPGAGAGS 102
            G  G    R   GP  P   PG  AGS
Sbjct: 1056 GPAGKSGDRGESGPAGPAGAPGP-AGS 1081


>gi|153070260 myristoylated alanine-rich protein kinase C substrate
           [Homo sapiens]
          Length = 332

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 45/200 (22%), Positives = 67/200 (33%), Gaps = 24/200 (12%)

Query: 33  GDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRRRAGGPPRP 92
           G E+G +    + +P A E G     +    AP   ++     G+  A       G P  
Sbjct: 33  GQENGHVKVNGDASPAAAESGAKEELQANGSAPAADKEEPAAAGSGAASPSAAEKGEPAA 92

Query: 93  MSEPGAGA------GSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPRDASDPLA 146
            + P AGA        +  + AEPG P                +E +AA A    S P A
Sbjct: 93  AAAPEAGASPVEKEAPAEGEAAEPGSP--------------TAAEGEAASAASSTSSPKA 138

Query: 147 GAALEPAGGGRSREARSRLLLLEQELKTVTYSLLKRLKERSLDTLLEAVESRGG----VP 202
                P+    + + + +    ++  K   +S  K  KE       EA  + GG      
Sbjct: 139 EDGATPSPSNETPKKKKKRFSFKKSFKLSGFSFKKNKKEAGEGGEAEAPAAEGGKDEAAG 198

Query: 203 GGCVLVPRADLRLGGQPAPP 222
           G       A    G Q A P
Sbjct: 199 GAAAAAAEAGAASGEQAAAP 218


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 24  EGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGA 80
           +G  G  G   +DG  G R  P  R   G  GG G +    P  P  P  + G+RGA G+
Sbjct: 880 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 939

Query: 81  GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
           G      G P P   PGA     +     P GP
Sbjct: 940 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 972



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 22/123 (17%)

Query: 14  WRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRSEVR--PVAPR 66
           ++ +  P    G  G  G   E G +G R  P P    G     G  G+   +  P  P 
Sbjct: 828 FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 887

Query: 67  RP--------RDAVGQRG----AQGAGRRRRAG--GPPRPMSEPG-AGAGSSLLDVAEPG 111
            P        R   G+RG    A G G +   G  GPP P   PG  GA  S   +  PG
Sbjct: 888 APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 947

Query: 112 GPG 114
            PG
Sbjct: 948 RPG 950



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 6/98 (6%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
            + G  G GG   +DG+ G R E     + G      E  P  P   R   G  G++G   
Sbjct: 1188 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1247

Query: 83   RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
             + A G P  +  PG            P GP   P  D
Sbjct: 1248 GKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPD 1279



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 27/94 (28%), Positives = 32/94 (34%), Gaps = 6/94 (6%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
           P    G  G  G   E G+ G   +  PR   G         P   R PR A G+ GA+G
Sbjct: 723 PKGSLGFPGFPGASGEKGARGLSGKSGPRGERG------PTGPRGQRGPRGATGKSGAKG 776

Query: 80  AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
                   GPP     PG    +       P GP
Sbjct: 777 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 810



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 3/65 (4%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
            G +G  G   EDG  G   +P  +  +G    + E  P  P  P   VGQ GA GA    
Sbjct: 986  GPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPPGPIGPVGQPGAAGADGEP 1042

Query: 85   RAGGP 89
             A GP
Sbjct: 1043 GARGP 1047



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 5/94 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGR 82
            +G  G  G     G +G +  P P   +G       + P  P  PR   G  GA G  G 
Sbjct: 1054 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1113

Query: 83   RRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                G  GPP    EPG      +    EPG  G
Sbjct: 1114 PGGVGNLGPPGEKGEPGESGSPGI--QGEPGVKG 1145



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 7/92 (7%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
            EG  GG G   + G++G+  +  P    G      +  P   R    +VGQ+G  GA  +
Sbjct: 1243 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA---GKPGPDGLRGLPGSVGQQGRPGATGQ 1299

Query: 84   RRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
                GPP P+  PG  G         E G PG
Sbjct: 1300 ---AGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1328



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 13/108 (12%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVR---PVAPRRPRDAVG 73
           P    G  G  G    +G  G +  P P  ++G  G  G R EV       P  P   VG
Sbjct: 783 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 842

Query: 74  QRGAQG-AGRRRRAG--GPPRPMSEPG----AGAGSSLLDVAEPGGPG 114
            +GA G  G     G  GPP P  E G    AG   +  D   PG PG
Sbjct: 843 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 890



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 18/109 (16%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREG-------GGCGRSEVRPVAPRRPRDAVGQR 75
            E G  G  GG    G+ G    P P    G       GG      RP  P+ P  A G++
Sbjct: 903  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP-GPQGPPGAAGEK 961

Query: 76   GAQG----AGRRRRAG-----GPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            G  G     G   R G     G P P   PG AG      +V +PG  G
Sbjct: 962  GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1010



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/90 (28%), Positives = 29/90 (32%), Gaps = 11/90 (12%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G SG  G   E G  G R +  PR   G    +       P  P    G  G QG     
Sbjct: 743 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 802

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
              GPP P  + G            PG PG
Sbjct: 803 GPKGPPGPPGKDGL-----------PGHPG 821



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 7/97 (7%)

Query: 25   GGSGGGGGGDEDGSLGSRAEP---APRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   E GS G + EP    PR   G      +     P  P+   G  G +G  
Sbjct: 1121 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1180

Query: 82   RRRRAGGPPRPMSEPGA----GAGSSLLDVAEPGGPG 114
                  G P P  E G     GA     +  EPG PG
Sbjct: 1181 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1217



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

Query: 37  GSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGRRRRAG 87
           G +G    P P  + G    + E   + P+ PR   G  G  G AGRR RAG
Sbjct: 404 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 455



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   ++G+ G    P P   +G  G  G + E   V P  P    G RG  G  
Sbjct: 1046 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1105

Query: 82   RRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                  GPP  +   G        +  E G PG
Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKG--EPGESGSPG 1136



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 12/97 (12%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCG-RSEVRPVAPRRPRDAVGQRGAQ 78
            P+  +G  G  GG    G  G + EP     E G  G + E     PR  R   G+ G  
Sbjct: 1104 PNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGEKGESGQP 1159

Query: 79   GAGRRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            G        GPP P    G  G   +   V  PG PG
Sbjct: 1160 G------EPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1190



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 22/75 (29%), Positives = 26/75 (34%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           + G  G  G   EDG  G   E  PR   G    R  + P  P       G RG  G   
Sbjct: 489 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 548

Query: 83  RRRAGGPPRPMSEPG 97
            + + GP      PG
Sbjct: 549 PKGSLGPQGEPGPPG 563



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 23/89 (25%), Positives = 31/89 (34%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G  G  G     GSLG + EP P  ++G    +    P     P    G +G  G     
Sbjct: 539 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 598

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
            + GPP    + G          + P GP
Sbjct: 599 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP 627



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/98 (24%), Positives = 31/98 (31%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
            PD   G  G  G     G+ G    P P    G    R +      +     +G  G  G
Sbjct: 1278 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1337

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLP 117
                +   G P P   PG      +   + P GPG  P
Sbjct: 1338 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1375



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 26/98 (26%), Positives = 31/98 (31%), Gaps = 17/98 (17%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRS---EVRPVAPRRPRDAVGQRG 76
            P    G  G  G     G +G    P P+   G    +    E  P+ P       G+ G
Sbjct: 924  PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP------TGRDG 977

Query: 77   AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
             QG        GPP    E G        D  E G PG
Sbjct: 978  VQGPVGLPGPAGPPGVAGEDG--------DKGEVGDPG 1007



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 8/79 (10%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-GGCGRSEVRPVAPRRPRDAVGQRGAQ 78
           P  ++G  G  G     G++G   E  P+ + G  G   S+  P  P       G+ G  
Sbjct: 561 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP-------GKEGPP 613

Query: 79  GAGRRRRAGGPPRPMSEPG 97
           G    +   GP  P+  PG
Sbjct: 614 GTKGNQGPSGPQGPLGYPG 632



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 8/139 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA----PRRPRDAVGQRGAQG 79
            +G  G  G   E G  G    P P+   G    +    PV     P  P +  G RG  G
Sbjct: 1144 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG-GPRGQDG 1202

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPR 139
            A   R   G P     PG    +         GP   P S+          +  A GAP 
Sbjct: 1203 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP- 1261

Query: 140  DASDPL--AGAALEPAGGG 156
              + P+  AG A +P   G
Sbjct: 1262 GKTGPVGPAGPAGKPGPDG 1280


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 24  EGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGA 80
           +G  G  G   +DG  G R  P  R   G  GG G +    P  P  P  + G+RGA G+
Sbjct: 859 KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 918

Query: 81  GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
           G      G P P   PGA     +     P GP
Sbjct: 919 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 951



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 22/123 (17%)

Query: 14  WRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRSEVR--PVAPR 66
           ++ +  P    G  G  G   E G +G R  P P    G     G  G+   +  P  P 
Sbjct: 807 FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 866

Query: 67  RP--------RDAVGQRG----AQGAGRRRRAG--GPPRPMSEPG-AGAGSSLLDVAEPG 111
            P        R   G+RG    A G G +   G  GPP P   PG  GA  S   +  PG
Sbjct: 867 APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 926

Query: 112 GPG 114
            PG
Sbjct: 927 RPG 929



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 6/98 (6%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
            + G  G GG   +DG+ G R E     + G      E  P  P   R   G  G++G   
Sbjct: 1167 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1226

Query: 83   RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
             + A G P  +  PG            P GP   P  D
Sbjct: 1227 GKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPD 1258



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 27/94 (28%), Positives = 32/94 (34%), Gaps = 6/94 (6%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
           P    G  G  G   E G+ G   +  PR   G         P   R PR A G+ GA+G
Sbjct: 702 PKGSLGFPGFPGASGEKGARGLSGKSGPRGERG------PTGPRGQRGPRGATGKSGAKG 755

Query: 80  AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
                   GPP     PG    +       P GP
Sbjct: 756 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 789



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 3/65 (4%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
            G +G  G   EDG  G   +P  +  +G    + E  P  P  P   VGQ GA GA    
Sbjct: 965  GPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPPGPIGPVGQPGAAGADGEP 1021

Query: 85   RAGGP 89
             A GP
Sbjct: 1022 GARGP 1026



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 5/94 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGR 82
            +G  G  G     G +G +  P P   +G       + P  P  PR   G  GA G  G 
Sbjct: 1033 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1092

Query: 83   RRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                G  GPP    EPG      +    EPG  G
Sbjct: 1093 PGGVGNLGPPGEKGEPGESGSPGI--QGEPGVKG 1124



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 7/92 (7%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
            EG  GG G   + G++G+  +  P    G      +  P   R    +VGQ+G  GA  +
Sbjct: 1222 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA---GKPGPDGLRGLPGSVGQQGRPGATGQ 1278

Query: 84   RRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
                GPP P+  PG  G         E G PG
Sbjct: 1279 ---AGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1307



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 13/108 (12%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVR---PVAPRRPRDAVG 73
           P    G  G  G    +G  G +  P P  ++G  G  G R EV       P  P   VG
Sbjct: 762 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 821

Query: 74  QRGAQG-AGRRRRAG--GPPRPMSEPG----AGAGSSLLDVAEPGGPG 114
            +GA G  G     G  GPP P  E G    AG   +  D   PG PG
Sbjct: 822 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 869



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 18/109 (16%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREG-------GGCGRSEVRPVAPRRPRDAVGQR 75
           E G  G  GG    G+ G    P P    G       GG      RP  P+ P  A G++
Sbjct: 882 ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP-GPQGPPGAAGEK 940

Query: 76  GAQG----AGRRRRAG-----GPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
           G  G     G   R G     G P P   PG AG      +V +PG  G
Sbjct: 941 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 989



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/90 (28%), Positives = 29/90 (32%), Gaps = 11/90 (12%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G SG  G   E G  G R +  PR   G    +       P  P    G  G QG     
Sbjct: 722 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 781

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
              GPP P  + G            PG PG
Sbjct: 782 GPKGPPGPPGKDGL-----------PGHPG 800



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 7/97 (7%)

Query: 25   GGSGGGGGGDEDGSLGSRAEP---APRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   E GS G + EP    PR   G      +     P  P+   G  G +G  
Sbjct: 1100 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1159

Query: 82   RRRRAGGPPRPMSEPGA----GAGSSLLDVAEPGGPG 114
                  G P P  E G     GA     +  EPG PG
Sbjct: 1160 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1196



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

Query: 37  GSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGRRRRAG 87
           G +G    P P  + G    + E   + P+ PR   G  G  G AGRR RAG
Sbjct: 383 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 434



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   ++G+ G    P P   +G  G  G + E   V P  P    G RG  G  
Sbjct: 1025 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1084

Query: 82   RRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                  GPP  +   G        +  E G PG
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKG--EPGESGSPG 1115



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 12/97 (12%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCG-RSEVRPVAPRRPRDAVGQRGAQ 78
            P+  +G  G  GG    G  G + EP     E G  G + E     PR  R   G+ G  
Sbjct: 1083 PNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGEKGESGQP 1138

Query: 79   GAGRRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            G        GPP P    G  G   +   V  PG PG
Sbjct: 1139 G------EPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1169



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 22/75 (29%), Positives = 26/75 (34%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           + G  G  G   EDG  G   E  PR   G    R  + P  P       G RG  G   
Sbjct: 468 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 527

Query: 83  RRRAGGPPRPMSEPG 97
            + + GP      PG
Sbjct: 528 PKGSLGPQGEPGPPG 542



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 23/89 (25%), Positives = 31/89 (34%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G  G  G     GSLG + EP P  ++G    +    P     P    G +G  G     
Sbjct: 518 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 577

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
            + GPP    + G          + P GP
Sbjct: 578 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP 606



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/98 (24%), Positives = 31/98 (31%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
            PD   G  G  G     G+ G    P P    G    R +      +     +G  G  G
Sbjct: 1257 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1316

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLP 117
                +   G P P   PG      +   + P GPG  P
Sbjct: 1317 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1354



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 26/98 (26%), Positives = 31/98 (31%), Gaps = 17/98 (17%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRS---EVRPVAPRRPRDAVGQRG 76
           P    G  G  G     G +G    P P+   G    +    E  P+ P       G+ G
Sbjct: 903 PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP------TGRDG 956

Query: 77  AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
            QG        GPP    E G        D  E G PG
Sbjct: 957 VQGPVGLPGPAGPPGVAGEDG--------DKGEVGDPG 986



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 8/79 (10%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-GGCGRSEVRPVAPRRPRDAVGQRGAQ 78
           P  ++G  G  G     G++G   E  P+ + G  G   S+  P  P       G+ G  
Sbjct: 540 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP-------GKEGPP 592

Query: 79  GAGRRRRAGGPPRPMSEPG 97
           G    +   GP  P+  PG
Sbjct: 593 GTKGNQGPSGPQGPLGYPG 611



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 8/139 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA----PRRPRDAVGQRGAQG 79
            +G  G  G   E G  G    P P+   G    +    PV     P  P +  G RG  G
Sbjct: 1123 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG-GPRGQDG 1181

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPR 139
            A   R   G P     PG    +         GP   P S+          +  A GAP 
Sbjct: 1182 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP- 1240

Query: 140  DASDPL--AGAALEPAGGG 156
              + P+  AG A +P   G
Sbjct: 1241 GKTGPVGPAGPAGKPGPDG 1259


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 31/93 (33%), Positives = 38/93 (40%), Gaps = 3/93 (3%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGA 80
            +G  G  G   +DG  G R  P  R   G  GG G +    P  P  P  + G+RGA G+
Sbjct: 966  KGDPGPPGAPGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGS 1025

Query: 81   GRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
            G      G P P   PGA     +     P GP
Sbjct: 1026 GGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP 1058



 Score = 38.5 bits (88), Expect = 0.014
 Identities = 37/123 (30%), Positives = 46/123 (37%), Gaps = 22/123 (17%)

Query: 14   WRSRVVPDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-----GGCGRSEVR--PVAPR 66
            ++ +  P    G  G  G   E G +G R  P P    G     G  G+   +  P  P 
Sbjct: 914  FQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPG 973

Query: 67   RP--------RDAVGQRG----AQGAGRRRRAG--GPPRPMSEPG-AGAGSSLLDVAEPG 111
             P        R   G+RG    A G G +   G  GPP P   PG  GA  S   +  PG
Sbjct: 974  APGKDGPAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPG 1033

Query: 112  GPG 114
             PG
Sbjct: 1034 RPG 1036



 Score = 37.7 bits (86), Expect = 0.024
 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 6/98 (6%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
            + G  G GG   +DG+ G R E     + G      E  P  P   R   G  G++G   
Sbjct: 1274 DPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQG 1333

Query: 83   RRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESD 120
             + A G P  +  PG            P GP   P  D
Sbjct: 1334 GKGAKGDPGAIGAPGKTGPVG------PAGPAGKPGPD 1365



 Score = 36.6 bits (83), Expect = 0.054
 Identities = 27/94 (28%), Positives = 32/94 (34%), Gaps = 6/94 (6%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
           P    G  G  G   E G+ G   +  PR   G         P   R PR A G+ GA+G
Sbjct: 809 PKGSLGFPGFPGASGEKGARGLSGKSGPRGERG------PTGPRGQRGPRGATGKSGAKG 862

Query: 80  AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
                   GPP     PG    +       P GP
Sbjct: 863 TSGGDGPHGPPGERGLPGPQGPNGFPGPKGPPGP 896



 Score = 35.8 bits (81), Expect = 0.092
 Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 3/65 (4%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
            G +G  G   EDG  G   +P  +  +G    + E  P  P  P   VGQ GA GA    
Sbjct: 1072 GPAGPPGVAGEDGDKGEVGDPGQKGTKGN---KGEHGPPGPPGPIGPVGQPGAAGADGEP 1128

Query: 85   RAGGP 89
             A GP
Sbjct: 1129 GARGP 1133



 Score = 35.4 bits (80), Expect = 0.12
 Identities = 28/94 (29%), Positives = 34/94 (36%), Gaps = 5/94 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGR 82
            +G  G  G     G +G +  P P   +G       + P  P  PR   G  GA G  G 
Sbjct: 1140 KGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPNGADGPQGP 1199

Query: 83   RRRAG--GPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                G  GPP    EPG      +    EPG  G
Sbjct: 1200 PGGVGNLGPPGEKGEPGESGSPGI--QGEPGVKG 1231



 Score = 34.3 bits (77), Expect = 0.27
 Identities = 28/92 (30%), Positives = 38/92 (41%), Gaps = 7/92 (7%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRR 83
            EG  GG G   + G++G+  +  P    G      +  P   R    +VGQ+G  GA  +
Sbjct: 1329 EGRQGGKGAKGDPGAIGAPGKTGPVGPAGPA---GKPGPDGLRGLPGSVGQQGRPGATGQ 1385

Query: 84   RRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
                GPP P+  PG  G         E G PG
Sbjct: 1386 ---AGPPGPVGPPGLPGLRGDAGAKGEKGHPG 1414



 Score = 33.9 bits (76), Expect = 0.35
 Identities = 36/108 (33%), Positives = 42/108 (38%), Gaps = 13/108 (12%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVR---PVAPRRPRDAVG 73
           P    G  G  G    +G  G +  P P  ++G  G  G R EV       P  P   VG
Sbjct: 869 PHGPPGERGLPGPQGPNGFPGPKGPPGPPGKDGLPGHPGQRGEVGFQGKTGPPGPPGVVG 928

Query: 74  QRGAQG-AGRRRRAG--GPPRPMSEPG----AGAGSSLLDVAEPGGPG 114
            +GA G  G     G  GPP P  E G    AG   +  D   PG PG
Sbjct: 929 PQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPG 976



 Score = 32.3 bits (72), Expect = 1.0
 Identities = 34/109 (31%), Positives = 40/109 (36%), Gaps = 18/109 (16%)

Query: 23   EEGGSGGGGGGDEDGSLGSRAEPAPRAREG-------GGCGRSEVRPVAPRRPRDAVGQR 75
            E G  G  GG    G+ G    P P    G       GG      RP  P+ P  A G++
Sbjct: 989  ERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRP-GPQGPPGAAGEK 1047

Query: 76   GAQG----AGRRRRAG-----GPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            G  G     G   R G     G P P   PG AG      +V +PG  G
Sbjct: 1048 GVPGEKGPIGPTGRDGVQGPVGLPGPAGPPGVAGEDGDKGEVGDPGQKG 1096



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 26/90 (28%), Positives = 29/90 (32%), Gaps = 11/90 (12%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G SG  G   E G  G R +  PR   G    +       P  P    G  G QG     
Sbjct: 829 GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGDGPHGPPGERGLPGPQGPNGFP 888

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
              GPP P  + G            PG PG
Sbjct: 889 GPKGPPGPPGKDGL-----------PGHPG 907



 Score = 32.0 bits (71), Expect = 1.3
 Identities = 29/97 (29%), Positives = 34/97 (35%), Gaps = 7/97 (7%)

Query: 25   GGSGGGGGGDEDGSLGSRAEP---APRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   E GS G + EP    PR   G      +     P  P+   G  G +G  
Sbjct: 1207 GPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNP 1266

Query: 82   RRRRAGGPPRPMSEPGA----GAGSSLLDVAEPGGPG 114
                  G P P  E G     GA     +  EPG PG
Sbjct: 1267 GPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPG 1303



 Score = 31.6 bits (70), Expect = 1.7
 Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 1/52 (1%)

Query: 37  GSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG-AGRRRRAG 87
           G +G    P P  + G    + E   + P+ PR   G  G  G AGRR RAG
Sbjct: 490 GPMGYTGRPGPLGQPGSPGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAG 541



 Score = 30.8 bits (68), Expect = 3.0
 Identities = 26/93 (27%), Positives = 33/93 (35%), Gaps = 5/93 (5%)

Query: 25   GGSGGGGGGDEDGSLGSRAEPAPRAREG--GGCG-RSEVRPVAPRRPRDAVGQRGAQGAG 81
            G  G  G   ++G+ G    P P   +G  G  G + E   V P  P    G RG  G  
Sbjct: 1132 GPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRGPAGPN 1191

Query: 82   RRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
                  GPP  +   G        +  E G PG
Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKG--EPGESGSPG 1222



 Score = 30.4 bits (67), Expect = 3.9
 Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 12/97 (12%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCG-RSEVRPVAPRRPRDAVGQRGAQ 78
            P+  +G  G  GG    G  G + EP     E G  G + E     PR  R   G+ G  
Sbjct: 1190 PNGADGPQGPPGGVGNLGPPGEKGEPG----ESGSPGIQGEPGVKGPRGERGEKGESGQP 1245

Query: 79   GAGRRRRAGGPPRPMSEPG-AGAGSSLLDVAEPGGPG 114
            G        GPP P    G  G   +   V  PG PG
Sbjct: 1246 G------EPGPPGPKGPTGDDGPKGNPGPVGFPGDPG 1276



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 22/75 (29%), Positives = 26/75 (34%)

Query: 23  EEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGR 82
           + G  G  G   EDG  G   E  PR   G    R  + P  P       G RG  G   
Sbjct: 575 DTGAQGLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQG 634

Query: 83  RRRAGGPPRPMSEPG 97
            + + GP      PG
Sbjct: 635 PKGSLGPQGEPGPPG 649



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 23/89 (25%), Positives = 31/89 (34%)

Query: 25  GGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQGAGRRR 84
           G  G  G     GSLG + EP P  ++G    +    P     P    G +G  G     
Sbjct: 625 GVRGMDGPQGPKGSLGPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMP 684

Query: 85  RAGGPPRPMSEPGAGAGSSLLDVAEPGGP 113
            + GPP    + G          + P GP
Sbjct: 685 GSDGPPGHPGKEGPPGTKGNQGPSGPQGP 713



 Score = 30.0 bits (66), Expect = 5.1
 Identities = 24/98 (24%), Positives = 31/98 (31%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVAPRRPRDAVGQRGAQG 79
            PD   G  G  G     G+ G    P P    G    R +      +     +G  G  G
Sbjct: 1364 PDGLRGLPGSVGQQGRPGATGQAGPPGPVGPPGLPGLRGDAGAKGEKGHPGLIGLIGPPG 1423

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLP 117
                +   G P P   PG      +   + P GPG  P
Sbjct: 1424 EQGEKGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP 1461



 Score = 29.6 bits (65), Expect = 6.6
 Identities = 26/98 (26%), Positives = 31/98 (31%), Gaps = 17/98 (17%)

Query: 20   PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRS---EVRPVAPRRPRDAVGQRG 76
            P    G  G  G     G +G    P P+   G    +    E  P+ P       G+ G
Sbjct: 1010 PPGPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGP------TGRDG 1063

Query: 77   AQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPG 114
             QG        GPP    E G        D  E G PG
Sbjct: 1064 VQGPVGLPGPAGPPGVAGEDG--------DKGEVGDPG 1093



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 21/79 (26%), Positives = 31/79 (39%), Gaps = 8/79 (10%)

Query: 20  PDREEGGSGGGGGGDEDGSLGSRAEPAPRAREG-GGCGRSEVRPVAPRRPRDAVGQRGAQ 78
           P  ++G  G  G     G++G   E  P+ + G  G   S+  P  P       G+ G  
Sbjct: 647 PPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHP-------GKEGPP 699

Query: 79  GAGRRRRAGGPPRPMSEPG 97
           G    +   GP  P+  PG
Sbjct: 700 GTKGNQGPSGPQGPLGYPG 718



 Score = 29.3 bits (64), Expect = 8.6
 Identities = 37/139 (26%), Positives = 47/139 (33%), Gaps = 8/139 (5%)

Query: 24   EGGSGGGGGGDEDGSLGSRAEPAPRAREGGGCGRSEVRPVA----PRRPRDAVGQRGAQG 79
            +G  G  G   E G  G    P P+   G    +    PV     P  P +  G RG  G
Sbjct: 1230 KGPRGERGEKGESGQPGEPGPPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEG-GPRGQDG 1288

Query: 80   AGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWLPESDCETVTCCLFSERDAAGAPR 139
            A   R   G P     PG    +         GP   P S+          +  A GAP 
Sbjct: 1289 AKGDRGEDGEPGQPGSPGPTGENGPPGPLGKRGPAGSPGSEGRQGGKGAKGDPGAIGAP- 1347

Query: 140  DASDPL--AGAALEPAGGG 156
              + P+  AG A +P   G
Sbjct: 1348 GKTGPVGPAGPAGKPGPDG 1366


>gi|4885407 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 4 [Homo sapiens]
          Length = 1203

 Score = 43.1 bits (100), Expect = 6e-04
 Identities = 59/220 (26%), Positives = 88/220 (40%), Gaps = 25/220 (11%)

Query: 3   RSKRSGLVRRLWRSRVVPDREEGGSGGGGGGDEDGS-----LGSRAEPAPRAREGGGCGR 57
           R +   L +++     + D EE     G GG +D S     L     P+P A  GG   R
Sbjct: 9   RKRLYSLPQQVGAKAWIMDEEEDAEEEGAGGRQDPSRRSIRLRPLPSPSPSAAAGGTESR 68

Query: 58  SEVRPVAPRR-PRDAVGQRGAQGAGRRRRAGGPPRPMSEPGAGAGSSLLDVAEPGGPGWL 116
           S     A    P    G+    G  RR R  G    +   G G+G +          G L
Sbjct: 69  SSALGAADSEGPARGAGKSSTNGDCRRFR--GSLASLGSRGGGSGGT----GSGSSHGHL 122

Query: 117 PESDCETVTCCLFSERDAAGAPRDASDPLAGAALEPAGGGRSREARSRLLLLEQELKTVT 176
            +S  E     L +E DA+    D + P  G A EP   G S +  +     +Q  +  +
Sbjct: 123 HDSAEERR---LIAEGDASPG-EDRTPP--GLAAEPERPGASAQPAASPPPPQQPPQPAS 176

Query: 177 YSLLKRLKERSLDTLLEAVESRGGVPGGCVLVPRADLRLG 216
            S     ++ S+DT   A++  GG   G  ++P A++RLG
Sbjct: 177 ASC----EQPSVDT---AIKVEGGAAAGDQILPEAEVRLG 209


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.138    0.436 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 24,914,301
Number of Sequences: 37866
Number of extensions: 1506409
Number of successful extensions: 13081
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 165
Number of HSP's successfully gapped in prelim test: 516
Number of HSP's that attempted gapping in prelim test: 8755
Number of HSP's gapped (non-prelim): 3170
length of query: 496
length of database: 18,247,518
effective HSP length: 106
effective length of query: 390
effective length of database: 14,233,722
effective search space: 5551151580
effective search space used: 5551151580
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.