BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] (950 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1889 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1697 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1574 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1548 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1532 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1532 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1526 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1520 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1516 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1514 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1498 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1498 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1497 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1489 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1382 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1234 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1227 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1222 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1215 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1207 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1206 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1200 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1192 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1191 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1184 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1179 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 942 0.0 gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 895 0.0 gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precurs... 818 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 804 0.0 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1889 bits (4892), Expect = 0.0 Identities = 950/950 (100%), Positives = 950/950 (100%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1697 bits (4394), Expect = 0.0 Identities = 859/942 (91%), Positives = 888/942 (94%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 K DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV +D+ Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV MVIDHFSIDRNTGEIVIRGNL Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 LVESGQAPKASSR S G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788 EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P + E Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 Query: 789 QDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 QDLN DH KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE Sbjct: 789 QDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 Query: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI Sbjct: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 Query: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1574 bits (4076), Expect = 0.0 Identities = 798/798 (100%), Positives = 798/798 (100%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 781 GSVDVGEEQDLNVDHGLK 798 GSVDVGEEQDLNVDHGLK Sbjct: 781 GSVDVGEEQDLNVDHGLK 798 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1548 bits (4009), Expect = 0.0 Identities = 781/950 (82%), Positives = 845/950 (88%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M + WR + G+ LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKD+NDN PVF + + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ + ++ F +D G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 ED+ TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ SAG GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 S D E+QD++VD KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1532 bits (3967), Expect = 0.0 Identities = 783/950 (82%), Positives = 832/950 (87%), Gaps = 14/950 (1%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 S D PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 780 TSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1532 bits (3966), Expect = 0.0 Identities = 767/946 (81%), Positives = 839/946 (88%) Query: 5 WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64 W+G +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF Sbjct: 5 WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64 Query: 65 RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124 RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+ Sbjct: 65 RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124 Query: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184 D+NDNPP+F +++ ++ESR P++RFPL+GASDAD+G NS LTYRL +DYF LD + Sbjct: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184 Query: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244 ++ + LVLRK+LDRE+ H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q Sbjct: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244 Query: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304 S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF V V+ F+I+ N GEI Sbjct: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304 Query: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364 +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q Sbjct: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364 Query: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424 +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV Sbjct: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424 Query: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484 VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA Sbjct: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484 Query: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544 QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544 Query: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604 LGSNVTLQVFVLDENDNAPALL P G GG S+L+PRSVGAGHVVAKVRAVDADSGYN Sbjct: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604 Query: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664 AWLSYELQ AA RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT Sbjct: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664 Query: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724 VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS Sbjct: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724 Query: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784 A PTEG C GKPTLVCSSA GSWSYSQQ+ RVCSGEGP KTDLMAFSP LPP LGS + Sbjct: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784 Query: 785 VGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 844 +++ + + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS Sbjct: 785 GTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSS 844 Query: 845 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 904 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT Sbjct: 845 ATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPT 904 Query: 905 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 905 NSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1526 bits (3952), Expect = 0.0 Identities = 770/950 (81%), Positives = 838/950 (88%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M + RG LG+ LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK HRDLLEV+LQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 V+VKD+NDNPPVFR ++Q +F+ ESR+ +SRFP+EGA+DAD+GAN++LTY LS DYF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + ++ +K + L LRK LDRE+ P HL LTATDGGKPEL GTV+LL+TVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+Q+ Y V + E NGT V LNASD DEG NG + +SF+S + + + F +D ++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + LD+E+ Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA TVIALI+V+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE +S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LS+Y+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GA S+LVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAA RIPFRVGLYTGEISTTRVLDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR S GV GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCS PTEG GKPTLVCSSA+GSWS SQQ+ QRVCS EGPPKTDLMAFSP L P L Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 + + E+ + N+D PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1520 bits (3935), Expect = 0.0 Identities = 773/945 (81%), Positives = 830/945 (87%), Gaps = 1/945 (0%) Query: 6 RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65 R LG+ RL L LLLL W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125 VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185 +NDNPPVF +++QKL ++ES+ DSRFPLEGASDAD+ N++LTYRLS ++YF LD + Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245 + K + L+L+KSLDRE P +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305 EY+V + ENA T V+KLNA+D DEG NG ++YS S ++ F++D+N GE+ + Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365 G LD+E+ YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425 TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485 TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALL + G GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQPAA RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725 LVSLVESGQAPKASSR AG PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785 PTEG C GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP L + Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 GEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 845 GE Q+ +H +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA Sbjct: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844 Query: 846 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 905 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN Sbjct: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904 Query: 906 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1516 bits (3925), Expect = 0.0 Identities = 769/950 (80%), Positives = 829/950 (87%), Gaps = 3/950 (0%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M++ W S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEV+D+NDNPPVF + L ++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 + ++ K + L+LRKSLDRE+AP L LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+++ Y+VR+ EN NGT VIKLNASD DEG NG I YSF++ + V F ID TG Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I+++G +DFE+ Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+R Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA GTVIALISV+D D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRE VSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSALPTEG C GKPTLVCSSAVGSWSYSQQ+ RVCSGEGPPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP--- 777 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 S D ++ + KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 778 DSRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 837 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 838 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 897 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 898 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1514 bits (3920), Expect = 0.0 Identities = 777/943 (82%), Positives = 828/943 (87%), Gaps = 3/943 (0%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+ Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K LVLRK LDRE+ P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VI+LNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547 Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 +TLQVFVLDENDNAPALL G GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQ AA RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667 Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 LVE QAPKASSR S GV PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726 Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787 EG C KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP VDV GE Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785 Query: 788 EQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 847 +Q + DH KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP Sbjct: 786 DQSIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 845 Query: 848 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 907 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ Sbjct: 846 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 905 Query: 908 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 906 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1498 bits (3878), Expect = 0.0 Identities = 763/950 (80%), Positives = 824/950 (86%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M Y RG+ LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKD+NDNPPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + N + K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+++ Y V++ EN GT VI NASD DEG NG I YSF+S V + F +D +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 I + G++DFE+ +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP +S IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SSR S G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA+PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG KTDLMAFSP L P Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 GS + E + D KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1498 bits (3878), Expect = 0.0 Identities = 768/941 (81%), Positives = 821/941 (87%), Gaps = 9/941 (0%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PPVFR ++QK+ VSES DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++ Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 L ELVLRK LDRE P +L L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 + EN N T VI+LNASDPDEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQPAA IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 C GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP S+ + E Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSP-------SLQLSRED 782 Query: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 LN +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 783 CLNPPS--EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1497 bits (3876), Expect = 0.0 Identities = 761/941 (80%), Positives = 815/941 (86%), Gaps = 13/941 (1%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN GT VI NASD DEG NG I YSF+S V + F +D +G I + G++D Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PRVGGTGGA +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A+ IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VESGQAPKASSR S G+ GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 G C KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP S D Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD----- 784 Query: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 785 --------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836 Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896 Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1489 bits (3855), Expect = 0.0 Identities = 754/941 (80%), Positives = 821/941 (87%), Gaps = 2/941 (0%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G+W LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK Sbjct: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PP+F + + + ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ + Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 + + LVL KSLDRE+ +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN NGT V+KLNASD DEG N I YS S V + + F+ID +GEI +G LD Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 +E+ Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVI Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PR G GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VESGQAPKASSR G G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 G GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L S + E+Q Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE--EKQ 787 Query: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 ++ KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 788 LSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847 Query: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907 Query: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1382 bits (3578), Expect = 0.0 Identities = 707/790 (89%), Positives = 736/790 (93%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 K DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV +D+ Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV MVIDHFSIDRNTGEIVIRGNL Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRS+GAG VVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQP ASS R PFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS Sbjct: 609 YELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 LVESGQAPKASSR S G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 LVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEE 788 EG C A KPTLVCSSAVGSWSYSQQ+ QRVCSGEGPPK DLMAFSP L P + E Sbjct: 729 EGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAEN 788 Query: 789 QDLNVDHGLK 798 QDLN DH K Sbjct: 789 QDLNEDHDAK 798 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1234 bits (3193), Expect = 0.0 Identities = 629/798 (78%), Positives = 693/798 (86%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M + WR + G+ LLL LLLLAA +VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKD+NDN PVF + + LF+SESR P SRF LEGASDAD+G NS+LTY L S +YF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV ++E K + LVL+K+L+RED P H+L +TA DGGKPELTGT QL +TVLDVNDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 FE++ Y+VR+ ENA NGT V+ +NA+D DEG N I+YSFN+ + ++ F +D G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I ++GN+DFE+ Y+I ++ATDKG+PPM+ HCTVL+ I+D NDNVPE+ + SLSLPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 ED+ TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRE VSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGG GGA S+LVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASS+ SAG GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG PKTDLMAFSP LPP Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 GSVDVGEEQDLNVDHGLK 798 S D E+QD++VD K Sbjct: 781 ISRDREEKQDVDVDLSAK 798 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1227 bits (3175), Expect = 0.0 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 Query: 781 GSVD 784 S D Sbjct: 780 TSTD 783 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1222 bits (3162), Expect = 0.0 Identities = 615/780 (78%), Positives = 681/780 (87%) Query: 5 WRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64 W+G +LLL LL+LAAW+ GSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF Sbjct: 5 WQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLF 64 Query: 65 RVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVK 124 RVASKRH DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHV+V+V+ Sbjct: 65 RVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVR 124 Query: 125 DVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNS 184 D+NDNPP+F +++ ++ESR P++RFPL+GASDAD+G NS LTYRL +DYF LD + Sbjct: 125 DINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQN 184 Query: 185 KNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQ 244 ++ + LVLRK+LDRE+ H L LTA+DGGKPELTGTVQLL+T+LDVNDNAP F Q Sbjct: 185 SLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQ 244 Query: 245 SEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVI 304 S Y+V + ENA NGT VIKLNA+DPD+G NG I YSF V V+ F+I+ N GEI Sbjct: 245 SVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRT 304 Query: 305 RGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQ 364 +G LDFE++ LY+I ++A DKG+ PMAGHCT+LV +LD NDN PE+ +TSLSLP+RED Q Sbjct: 305 KGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQ 364 Query: 365 FGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELV 424 +IALISV+D DSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRE VSAYELV Sbjct: 365 PSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELV 424 Query: 425 VTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADA 484 VTARDGGSPSLWATAS+SV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA+DADA Sbjct: 425 VTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADA 484 Query: 485 QENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPP 544 QENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD+GVPP Sbjct: 485 QENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPP 544 Query: 545 LGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYN 604 LGSNVTLQVFVLDENDNAPALL P G GG S+L+PRSVGAGHVVAKVRAVDADSGYN Sbjct: 545 LGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYN 604 Query: 605 AWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATAT 664 AWLSYELQ AA RIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALTATAT Sbjct: 605 AWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATAT 664 Query: 665 VLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724 VL+SLVESGQAP+ASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS Sbjct: 665 VLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCS 724 Query: 725 ALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784 A PTEG C GKPTLVCSSA GSWSYSQQ+ RVCSGEGP KTDLMAFSP LPP LGS + Sbjct: 725 APPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAE 784 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1215 bits (3143), Expect = 0.0 Identities = 618/794 (77%), Positives = 686/794 (86%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M + RG LG+ LLL LLLLAAW+VGSGQLHYS+PEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK HRDLLEV+LQNGILFVNSRIDREELC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 V+VKD+NDNPPVFR ++Q +F+ ESR+ +SRFP+EGA+DAD+GAN++LTY LS DYF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + ++ +K + L LRK LDRE+ P HL LTATDGGKPEL GTV+LL+TVLDVNDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+Q+ Y V + E NGT V LNASD DEG NG + +SF+S + + + F +D ++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 EI + LD+E+ Y+I + A DKG PPM+ HC VLV++LD NDN PE+A+TSL LP+R Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA TVIALI+V+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE +S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LS+Y+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GA S+LVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAA RIPFRVGLYTGEISTTRVLDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR S GV GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCS PTEG GKPTLVCSSA+GSWS SQQ+ QRVCS EGPPKTDLMAFSP L P L Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 GSVDVGEEQDLNVD 794 + + E+ + N+D Sbjct: 781 NTSERNEQPEANLD 794 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1207 bits (3124), Expect = 0.0 Identities = 621/790 (78%), Positives = 677/790 (85%), Gaps = 1/790 (0%) Query: 6 RGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR 65 R LG+ RL L LLLL W+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKD 125 VASK H DLLEV+LQNGILFVNSRIDREELCG+SAECSIHLEVIVDRPLQVFHV+VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 VNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSK 185 +NDNPPVF +++QKL ++ES+ DSRFPLEGASDAD+ N++LTYRLS ++YF LD + Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 NDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQS 245 + K + L+L+KSLDRE P +L LTATDGGKPELTGTV+LLV VLDVNDN P F++S Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 EYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIR 305 EY+V + ENA T V+KLNA+D DEG NG ++YS S ++ F++D+N GE+ + Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQF 365 G LD+E+ YKI + ATDKG PPMAGHCTV V ILD NDN PE+A+TSLSLPVREDAQ Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 GTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVV 425 TVIALISV+D DSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 485 TARDGGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+R+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALL + G GGA +KLVPRSVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQPAA RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 725 LVSLVESGQAPKASSR AG PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL SA Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 LPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV 785 PTEG C GKPTLVCS AVGSWSYSQQ+ QRVCS EGPPKTDLMAFSP LP L + Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 GEEQDLNVDH 795 GE Q+ +H Sbjct: 785 GERQEPGSNH 794 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1206 bits (3121), Expect = 0.0 Identities = 614/777 (79%), Positives = 671/777 (86%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M++ W S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEV+D+NDNPPVF + L ++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 + ++ K + L+LRKSLDRE+AP L LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+++ Y+VR+ EN NGT VIKLNASD DEG NG I YSF++ + V F ID TG Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 +I+++G +DFE+ Y+I+++ DKG P++GHC V+V + D NDNVP++ SLSLP+R Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDA GTVIALISV+D D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRE VSA Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPKASSR G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777 LRCSALPTEG C GKPTLVCSSAVGSWSYSQQ+ RVCSGEGPPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1200 bits (3104), Expect = 0.0 Identities = 625/791 (79%), Positives = 676/791 (85%), Gaps = 3/791 (0%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+ Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K LVLRK LDRE+ P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VI+LNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSN 547 Query: 549 VTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 +TLQVFVLDENDNAPALL G GGA S+LV RSV AGHVVAKVRAVDADSGYNAWLS Sbjct: 548 LTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLS 607 Query: 609 YELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVS 668 YELQ AA RIPFRVGLYTGEISTTR LDE DSPR RLLVLVKDHGEP+LTATATVLVS Sbjct: 608 YELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVS 667 Query: 669 LVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPT 728 LVE QAPKASSR S GV PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 668 LVEGSQAPKASSRASVGV-APEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPT 726 Query: 729 EGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDV-GE 787 EG C KPTLVCSSAVGSWSYSQQ+ QRVCSGEG PK DLMAFSP LPP VDV GE Sbjct: 727 EGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPP-CPMVDVDGE 785 Query: 788 EQDLNVDHGLK 798 +Q + DH K Sbjct: 786 DQSIGGDHSRK 796 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1192 bits (3084), Expect = 0.0 Identities = 609/775 (78%), Positives = 663/775 (85%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 10 GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN Sbjct: 70 FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + Sbjct: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V Sbjct: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN GT VI NASD DEG NG I YSF+S V + F +D +G I + G++D Sbjct: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI Sbjct: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PRVGGTGGA +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQP A+ IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL Sbjct: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VESGQAPKASSR S G+ GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784 G C KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP S D Sbjct: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1191 bits (3081), Expect = 0.0 Identities = 613/767 (79%), Positives = 663/767 (86%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK Sbjct: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PPVFR ++QK+ VSES DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++ Sbjct: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 L ELVLRK LDRE P +L L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 + EN N T VI+LNASDPDEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQPAA IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776 C GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L Sbjct: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1184 bits (3064), Expect = 0.0 Identities = 610/794 (76%), Positives = 671/794 (84%) Query: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 M Y RG+ LLL LL+LA W VGSGQLHYSVPEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLF++ SK DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 VEVKD+NDNPPVF + LF++ESR DSRFPLEGASDAD+G N++LTYRLS ++YF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 DV + N + K + LVLRK LDRE+ P HL LTATDGGKPELTGTVQLL+TVLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 F+++ Y V++ EN GT VI NASD DEG NG I YSF+S V + F +D +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 I + G++DFE+ +KI ++A DKG PP+AGHCT+LV ++D NDN P++ + +LS+PV+ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 EDAQ GTVIALISV DLD+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRE VSA Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 YELVVTARDGGSPSLWATA +SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQENALVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GA S++V RSVGAG VV KVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP +S IPFRVGLYTGEISTTR LDE D+PR RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 ATATVLVSLVESGQAPK+SSR S G GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 LRCSA+PTEG C GKPTLVCSSAVGSWSYSQQ+ QRVCSGEG KTDLMAFSP L P Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 781 GSVDVGEEQDLNVD 794 GS + E + D Sbjct: 781 GSTERTGEPSASSD 794 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1179 bits (3050), Expect = 0.0 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%) Query: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G+W LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK Sbjct: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN Sbjct: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 PP+F + + + ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ + Sbjct: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 + + LVL KSLDRE+ +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V Sbjct: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 ++ EN NGT V+KLNASD DEG N I YS S V + + F+ID +GEI +G LD Sbjct: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 +E+ Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVI Sbjct: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PR G GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL Sbjct: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 VESGQAPKASSR G G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 Query: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 G GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L D EE+ Sbjct: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786 Query: 790 DLN 792 L+ Sbjct: 787 QLS 789 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 942 bits (2435), Expect = 0.0 Identities = 476/526 (90%), Positives = 501/526 (95%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFR+AS Sbjct: 9 LGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMAS 68 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 K DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEV+D+ND Sbjct: 69 KDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIND 128 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP+F V++Q++ + ESR+PDS FPLEGASDADVG+NS+LTY+LSS +YF LDV +D+ Sbjct: 129 NPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDD 188 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 NK + L+L+KSLDRE+APAH+LFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE Sbjct: 189 NKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 VRIFENADNGTTVI+LNASD DEGANGAISYSFNSLV MVIDHFSIDRNTGEIVIRGNL Sbjct: 249 VRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNL 308 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV Sbjct: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISVNDLDSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTAR Sbjct: 369 IALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSPSLWATASLSVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA Sbjct: 429 DGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQ 534 LVSYSLVERRVGER+LSSYISVH ESGKVYALQPLDHEELELLQFQ Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 434 bits (1116), Expect = e-121 Identities = 274/620 (44%), Positives = 341/620 (55%), Gaps = 61/620 (9%) Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPF-- 395 V + D NDN P + + + E +V L +D D G+N +T L F Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 396 --KLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAP 453 K+ S L+L +LDRE A+ L +TA DGG P L T L V V DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTE 513 F Q EY V + EN G + ++A D D N +SYS + + + S+ Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSIDRN 298 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGT 573 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + + Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSL--- 355 Query: 574 GGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFR-VGLYTGEIS 632 S V G V+A + D DSG N ++ L +P +PF+ V + S Sbjct: 356 ----SLPVREDAQFGTVIALISVNDLDSGANGQVNCSL-----TPHVPFKLVSTFKNYYS 406 Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE 690 LD + L+V +D G P+L ATA++ V + + A ++ V E Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKE 466 Query: 691 AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGGCRAGKPTLVCSSAVGSWSY 750 +++ + A A + L+ Y+ + R G+ L +V + S Sbjct: 467 NNPPGCHIFTVSARDADAQ--ENALVSYSLVE---------RRVGERALSSYISVHAESG 515 Query: 751 SQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQDLNVDHGLKPRQPNPDWRYSA 810 Q + E +L+ F P RQPNPDWRYSA Sbjct: 516 KVYALQPLDHEE----LELLQFQP-------------------------RQPNPDWRYSA 546 Query: 811 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 870 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK Sbjct: 547 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 606 Query: 871 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 930 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK Sbjct: 607 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 666 Query: 931 GNKTQEKKEKGNSTTDNSDQ 950 GNKTQEKKEKGNSTTDNSDQ Sbjct: 667 GNKTQEKKEKGNSTTDNSDQ 686 Score = 162 bits (411), Expect = 1e-39 Identities = 116/394 (29%), Positives = 187/394 (47%), Gaps = 32/394 (8%) Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMV 289 V V D+NDN P F E V I+E+ + ASD D G+N ++Y +S Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSS----- 175 Query: 290 IDHFSIDRNTGE-------IVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILD 342 ++F +D ++++ +LD E+ + + + ATD G P + G +LV +LD Sbjct: 176 -EYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLD 234 Query: 343 KNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTF- 401 NDN P + + + E+A GT + ++ +D D GANG ++ S V ++ F Sbjct: 235 VNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFS 294 Query: 402 --KNYYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPE 459 +N +V+ LD E+ + Y++++ A D G P + ++ V + D NDN P A Sbjct: 295 IDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTS 354 Query: 460 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGE--RSLSSYISVHTESGKV 517 ++ V+E+ G I +S D D+ N V+ SL + + +Y S+ +S Sbjct: 355 LSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSA-- 412 Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAA 577 LD E + + V+ARD G P L + +L V V D NDNAPA +P Sbjct: 413 -----LDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEY------- 460 Query: 578 SKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611 + V + G + V A DAD+ NA +SY L Sbjct: 461 TVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Score = 43.5 bits (101), Expect = 0.001 Identities = 53/198 (26%), Positives = 86/198 (43%), Gaps = 22/198 (11%) Query: 484 AQENALVSYSLVER--RVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAG 541 AQ+ L LV R R+ + + V+ ++G ++ +D EEL + S Sbjct: 49 AQDLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEV 108 Query: 542 VPPLGSNVT-LQVFVLDENDNAPA--LLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVD 598 + V + V V D NDN P + E RV L+ S V A D Sbjct: 109 IVDRPLQVFHVDVEVRDINDNPPLFPVEEQRV---------LIYESRLPDSVFPLEGASD 159 Query: 599 ADSGYNAWLSYELQPAASSPRIPFRVGLYTGE-----ISTTRVLDEADSPRHRLLVLVKD 653 AD G N+ L+Y+L +SS V + + + + + LD ++P H L + D Sbjct: 160 ADVGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATD 216 Query: 654 HGEPALTATATVLVSLVE 671 G+P LT T +LV++++ Sbjct: 217 GGKPELTGTVQLLVTVLD 234 >gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor [Homo sapiens] Length = 1007 Score = 895 bits (2313), Expect = 0.0 Identities = 496/990 (50%), Positives = 636/990 (64%), Gaps = 64/990 (6%) Query: 15 LLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRV-----ASK 69 LLLLLLL + QL YSVPEE G VG +A+ LGLEL L P R+ S Sbjct: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87 Query: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 R+ LE+ L +G LFVN RIDRE LC + C + LEV+ P+ V V+VE+ D+NDN Sbjct: 88 RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144 Query: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 P F + +L VSES P +RF +E A D DVGANSV TY LS ++F LD+ + + Sbjct: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204 Query: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 K++ELVLRK LDRE A HHL LTA DGG P +GT Q+ V VLD NDN+P F+QS Y V Sbjct: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264 Query: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 ++ E++ GT V+KLNASDPDEG+NG + YS +S FSID +TGE+ + G LD Sbjct: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324 Query: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 +E+ + Y+I + ATD+G PMAGHC VLV I+D NDN PE+ LT L PV E+A T++ Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384 Query: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 A++SVND DSG N +V+ L +PF+L + F N Y+LV+ LDRERV+ Y + VTA D Sbjct: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443 Query: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 GG P L + +L VE++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA Sbjct: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503 Query: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 V+YSL+ER + ++SY+S+++ SG +YA+ D+E+ V A+D G PPL S V Sbjct: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563 Query: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 T V+V+D ND+AP +L P AA ++VPR+ AG++V KV A+D+DSG NAWL Y Sbjct: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622 Query: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 L A +S F+V L+TGEI TTR + + L V+V+D+GEP+L+A+ + V++ Sbjct: 623 HL--AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680 Query: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 V+ + K V P ++ +YLIIA+ VS + +LT+++ + ++C Sbjct: 681 VD--RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAY 737 Query: 730 G--------GCRAGKPTLVCSSA---------------------VGSWSYSQQQPQRVCS 760 G G R P + A G+ S ++ + C Sbjct: 738 GTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACL 797 Query: 761 GEGPPKTDLMAFSPCLP----PDLGSVDVGEEQDLNVDHGL----------------KPR 800 G M ++ P V + ++L G +PR Sbjct: 798 TAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPR 857 Query: 801 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 860 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA Sbjct: 858 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 917 Query: 861 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 920 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE Sbjct: 918 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 977 Query: 921 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 978 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007 >gi|14717401 protocadherin alpha subfamily C, 1 isoform 1 precursor [Homo sapiens] Length = 963 Score = 818 bits (2112), Expect = 0.0 Identities = 455/963 (47%), Positives = 590/963 (61%), Gaps = 36/963 (3%) Query: 17 LLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHRDLLE 76 +L L + +GQL YSVPEE + G VG ++ DL L A + R FR S Sbjct: 8 VLCLWVSCGAAAGQLEYSVPEETERGVAVGNLSADLRLPAAAMSSRNFRFLSSHRELYFG 67 Query: 77 VSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDNPPVFRVK 136 V L +G L V DRE+LC A C + +++++ PL++ + + V D NDN P+F Sbjct: 68 VDLPSGNLVVREPADREQLCRAKAACVLTYDLVLEDPLELHKIRIHVLDTNDNSPLFPAG 127 Query: 137 DQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDENKLVELVL 196 D +L + E P +RF L A D D G+N +L+Y LS +F LD+ S+ D ++ ELVL Sbjct: 128 DVQLHIPEFLTPGARFTLPNAQDDDEGSNGILSYSLSPSQHFRLDMGSRVDGSEYPELVL 187 Query: 197 RKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENAD 256 K+LDRE H L LTA DGG P +G Q+ + V+D NDNAP FE+S Y ++ E A Sbjct: 188 EKALDREQRATHLLVLTARDGGLPARSGDAQVTIIVVDTNDNAPVFERSVYRTKVPETAP 247 Query: 257 NGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLDFEQENLY 316 NGT + ++ A DPDEG+NG + YS ++ + + F + +GE+ + +L E L Sbjct: 248 NGTVLFRVQALDPDEGSNGEVQYSLSNSTQAELRHRFHVHPKSGEVQVAASLG-PPETLL 306 Query: 317 KILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVND 376 + I+A D+G +A +LV + D ND+ PE+ +LS PV EDA GTVIAL SV D Sbjct: 307 EAYIEARDEGVFGLASTAKLLVEVTDVNDHAPELDFLTLSNPVPEDAAPGTVIALFSVKD 366 Query: 377 LDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARDGGSPSLW 436 D +NG+V C + PF+L ++F NYYSL++D LDRE++S Y++++TA D GSP L Sbjct: 367 EDLDSNGRVICGMSSAGPFQLTASFDNYYSLLIDGPLDREQISEYQVLITASDSGSPPLS 426 Query: 437 ATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVE 496 +++V VADVNDN P F QP+ +FV ENN PG + V A+D D +N LVSY L++ Sbjct: 427 TRRTITVSVADVNDNTPNFPQPQQELFVAENNGPGASLGRVFAQDPDLGKNGLVSYELLD 486 Query: 497 RRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVL 556 S SS ++V + SG + A D E+L FQV RD G+PP + VT+ +FV+ Sbjct: 487 VISEGPSASSLLAVESSSGAITAKTSFDFEQLRGFHFQVEGRDGGIPPRSATVTINLFVV 546 Query: 557 DENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAS 616 D NDN P +L P + G ++VPRS GH+V KV A DADSG NAWLSY + A+ Sbjct: 547 DRNDNYPVILFP-LPRNGSVPVEIVPRSARTGHLVTKVVAEDADSGSNAWLSYHISRASD 605 Query: 617 SPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAP 676 S FR+ GE+ T R++ D+ + R++V+V+DHG+P L+++ T+ V L S P Sbjct: 606 SSL--FRISANIGELRTARLVLPTDAVKQRVVVVVRDHGDPPLSSSVTLGVLL--SNSVP 661 Query: 677 KASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP---TEGGCR 733 + V P L N+YL+IA+ +S L + LL + + P + CR Sbjct: 662 QLLP-DFEDVWEPGGQLSAQNLYLVIALACISFLFLGCLLFFVCTKLHQSPGCCAQSCCR 720 Query: 734 AGKPTLVCSSAVGS-------------WSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 + + S V + SQ R G G L+ DL Sbjct: 721 STEDLRYGSKMVSNPCMTSATIDVTTVERLSQTYLYRASLGLGSDNNSLLLRGEYNAADL 780 Query: 781 GSVDVGEEQDLNV----------DHG---LKPRQPNPDWRYSASLRAGMHSSVHLEEAGI 827 ++ G +L + DH PRQPNPDWRYSASLRAGMHSSVHLEEAGI Sbjct: 781 RNLATGVGLNLPISCIQIRNRKGDHANVNAMPRQPNPDWRYSASLRAGMHSSVHLEEAGI 840 Query: 828 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 887 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK Sbjct: 841 LRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDK 900 Query: 888 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 947 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN Sbjct: 901 FIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDN 960 Query: 948 SDQ 950 SDQ Sbjct: 961 SDQ 963 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 804 bits (2076), Expect = 0.0 Identities = 409/526 (77%), Positives = 454/526 (86%) Query: 9 LGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 LG LLL LLLLAAW+VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVAS Sbjct: 8 LGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVAS 67 Query: 69 KRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVND 128 KRH DLLEV+LQNGILFVNSRIDREELCGRS ECSIHLEVIVDRPLQVFHVDVEVKD+ND Sbjct: 68 KRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDIND 127 Query: 129 NPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDE 188 NPP F V +QKL + ESR+ DSRFPLEGASDADVG N++LTY+LS ++YF+LD+ +K D+ Sbjct: 128 NPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDK 187 Query: 189 NKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYE 248 +K LVLRK LDRE+ P L LTATDGGKPE TG+V LL+ VLD NDNAP F++ YE Sbjct: 188 DKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYE 247 Query: 249 VRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNL 308 V+++EN N T VI+LNASD DEG N + YSF+SLV + F I+ TGEI + + Sbjct: 248 VKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAI 307 Query: 309 DFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTV 368 DFE N Y+I +D TDKG+PPM GHCTVLV +LD+NDN PE+ +TSLSLPV+EDAQ GTV Sbjct: 308 DFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTV 367 Query: 369 IALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTAR 428 IALISV+D DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRERVSAYELVVTAR Sbjct: 368 IALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTAR 427 Query: 429 DGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENA 488 DGGSP LWATAS+SVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENA Sbjct: 428 DGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENA 487 Query: 489 LVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQ 534 LVSYSLVERR+GERSLSSY+SVH ESGKVYALQPLDHEELELLQFQ Sbjct: 488 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 423 bits (1087), Expect = e-118 Identities = 270/620 (43%), Positives = 340/620 (54%), Gaps = 61/620 (9%) Query: 338 VRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKL 397 V + D NDN P ++T L + E + L +D D G N +T L P+ F L Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 398 VSTFKN----YYSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAP 453 K + LVL LDRE +L++TA DGG P + SL + V D NDNAP Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTE 513 F +P Y V + EN + ++A D+D N + YS + ++ ++ Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINER 297 Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGT 573 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ + Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSL--- 354 Query: 574 GGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAASSPRIPFR-VGLYTGEIS 632 S V G V+A + D DSG N ++ L +P +PF+ V Y S Sbjct: 355 ----SLPVKEDAQVGTVIALISVSDHDSGANGQVTCSL-----TPHVPFKLVSTYKNYYS 405 Query: 633 TT--RVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRQSAGVLGPE 690 LD + L+V +D G P L ATA+V V + + A ++ V E Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465 Query: 691 AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGGCRAGKPTLVCSSAVGSWSY 750 +++ + A A + L+ Y+ + R G+ +L +V + S Sbjct: 466 NNPPGCHIFTVSAWDADAQ--ENALVSYSLVE---------RRLGERSLSSYVSVHAESG 514 Query: 751 SQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQDLNVDHGLKPRQPNPDWRYSA 810 Q + E +L+ F P RQPNPDWRYSA Sbjct: 515 KVYALQPLDHEE----LELLQFQP-------------------------RQPNPDWRYSA 545 Query: 811 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 870 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK Sbjct: 546 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 605 Query: 871 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 930 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK Sbjct: 606 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 665 Query: 931 GNKTQEKKEKGNSTTDNSDQ 950 GNKTQEKKEKGNSTTDNSDQ Sbjct: 666 GNKTQEKKEKGNSTTDNSDQ 685 Score = 144 bits (362), Expect = 5e-34 Identities = 116/387 (29%), Positives = 186/387 (48%), Gaps = 18/387 (4%) Query: 230 VTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMV 289 V V D+NDN P F +E ++ I E+ + ASD D G N ++Y S E V Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKL-SPNEYFV 178 Query: 290 IDHFSI-DRNTGEI-VIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNV 347 +D + D++ + V+R LD E+ K+L+ ATD G P G ++L+ +LD NDN Sbjct: 179 LDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238 Query: 348 PEIALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTF---KNY 404 P + + E+ T++ ++ +D D G N ++ S VP + F + Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298 Query: 405 YSLVLDSALDRERVSAYELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFV 464 + ++ A+D E + YE+ V D G+P + ++ VE+ D NDN+P ++ V Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358 Query: 465 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLD 524 KE+ G I +S D D+ N V+ SL V + +S+Y + ++ + LD Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVLDSALD 413 Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRS 584 E + + V+ARD G PPL + ++ V V D NDNAPA + + V + Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEY-------TVFVKEN 466 Query: 585 VGAGHVVAKVRAVDADSGYNAWLSYEL 611 G + V A DAD+ NA +SY L Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.133 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 39,352,199 Number of Sequences: 37866 Number of extensions: 1995773 Number of successful extensions: 14418 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 209 Number of HSP's successfully gapped in prelim test: 75 Number of HSP's that attempted gapping in prelim test: 6797 Number of HSP's gapped (non-prelim): 1201 length of query: 950 length of database: 18,247,518 effective HSP length: 112 effective length of query: 838 effective length of database: 14,006,526 effective search space: 11737468788 effective search space used: 11737468788 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.