Search of human proteins with 9256594

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo
sapiens]
         (937 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1862   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1664   0.0  
gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1582   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1548   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1535   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1513   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1505   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1504   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1503   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1497   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1493   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1487   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1482   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1474   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1361   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1276   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1233   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1202   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1200   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1200   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1199   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1192   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1187   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1184   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1178   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1169   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   857   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   786   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   778   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   774   0.0  

>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1862 bits (4824), Expect = 0.0
 Identities = 937/937 (100%), Positives = 937/937 (100%)

Query: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60
           MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV
Sbjct: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60

Query: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120
           PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD
Sbjct: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360
           AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360

Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480

Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660
           SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT
Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP
Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780

Query: 781 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 840
           SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE
Sbjct: 781 SSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 840

Query: 841 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 900
           VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF
Sbjct: 841 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 900

Query: 901 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1664 bits (4309), Expect = 0.0
 Identities = 850/943 (90%), Positives = 874/943 (92%), Gaps = 13/943 (1%)

Query: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67
           DP G+ LLL ++ILA W  G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+  
Sbjct: 8   DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67

Query: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127
            K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN
Sbjct: 68  SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ
Sbjct: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY
Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
           TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH
Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367
           MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT
Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367

Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VI LISV D D   NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA
Sbjct: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487

Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607

Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667
           SYELQP  A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV
Sbjct: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667

Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727
           SLVESGQAPK+SSRAS+G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA  
Sbjct: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727

Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL----------- 776
           +EG C+  KPTLVCSSAVGSWS+SQQRRQRVCSGEG  KTDLMAFSP L           
Sbjct: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTG 787

Query: 777 -PQGPS-STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 834
            P   S ST  PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP
Sbjct: 788 EPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 847

Query: 835 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 894
           EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ
Sbjct: 848 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 907

Query: 895 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 908 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1582 bits (4097), Expect = 0.0
 Identities = 806/936 (86%), Positives = 846/936 (90%), Gaps = 10/936 (1%)

Query: 12  RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71
           R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR   K R
Sbjct: 12  RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131
           G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP
Sbjct: 72  GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131

Query: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
           VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P  ++ VK 
Sbjct: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
           LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L
Sbjct: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE
Sbjct: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371
           ES++++I VE +DKG  PL+GHC V+VEV D NDN P L   SLSLPI EDA  GTVI L
Sbjct: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371

Query: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV D+D GVNG VTCSLT  VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG
Sbjct: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491
           SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491

Query: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671
           QP   GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731
           SGQAPKASSRA +G  GP+  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +EGA
Sbjct: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731

Query: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD------- 784
           C+  KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP      D       
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEE 791

Query: 785 ---NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 841
               PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV
Sbjct: 792 SFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 851

Query: 842 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 901
           SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI
Sbjct: 852 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 911

Query: 902 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 912 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1548 bits (4008), Expect = 0.0
 Identities = 785/785 (100%), Positives = 785/785 (100%)

Query: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60
           MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV
Sbjct: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60

Query: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120
           PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD
Sbjct: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL
Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
           DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
           VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360
           AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360

Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480

Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660
           SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT
Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP
Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780

Query: 781 SSTDN 785
           SSTDN
Sbjct: 781 SSTDN 785


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1535 bits (3975), Expect = 0.0
 Identities = 782/943 (82%), Positives = 837/943 (88%), Gaps = 13/943 (1%)

Query: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67
           DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR  
Sbjct: 8   DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127
            K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127

Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DN PVFP   +NLFI+ESR   SRF LEGASDADIG N+LLTY L   EYF LDV  +++
Sbjct: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y
Sbjct: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
            V+L EN   GTLV+  NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+
Sbjct: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367
           +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+   T
Sbjct: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367

Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487
           RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487

Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667
           SYELQP   GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV
Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667

Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727
           SLVESGQAPKASS+AS G  GPE  LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP 
Sbjct: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD--- 784
           +EG C   KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP  P S D   
Sbjct: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREE 787

Query: 785 ----------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 834
                      PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP
Sbjct: 788 KQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 847

Query: 835 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 894
           EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ
Sbjct: 848 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 907

Query: 895 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 908 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1513 bits (3918), Expect = 0.0
 Identities = 767/927 (82%), Positives = 821/927 (88%)

Query: 11  GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70
           G  LLL  ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR   K 
Sbjct: 10  GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69

Query: 71  RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130
           RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP
Sbjct: 70  RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129

Query: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190
           P F   ++ LFI ESR  DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++  
Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189

Query: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250
            L LVLRK LDREET E  LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+
Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249

Query: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310
           L EN   GTLVI  NASD DEG+N +I+Y FS+ V  D+KSKF ++  +G I V G +D+
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309

Query: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370
           E+  +++I ++A+DK   PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA   TVI 
Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369

Query: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430
           LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG
Sbjct: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429

Query: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490
           GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV
Sbjct: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489

Query: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550
           SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT
Sbjct: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549

Query: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610
           LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE
Sbjct: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609

Query: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670
           LQP    A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV
Sbjct: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669

Query: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730
           ESGQAPKASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E 
Sbjct: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729

Query: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPN 790
            C+  KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDNPRQPN
Sbjct: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNPRQPN 789

Query: 791 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 850
           PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN
Sbjct: 790 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 849

Query: 851 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 910
           SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK
Sbjct: 850 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 909

Query: 911 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 910 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 936


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1505 bits (3897), Expect = 0.0
 Identities = 767/942 (81%), Positives = 822/942 (87%), Gaps = 13/942 (1%)

Query: 9   PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68
           P  R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   
Sbjct: 9   PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128

Query: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
           NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD   S +Q
Sbjct: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188

Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
           +  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y 
Sbjct: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248

Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
           V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G I   G +
Sbjct: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308

Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368
           DFEE + ++I VEAVDKG  P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP  +
Sbjct: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368

Query: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488
           DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488

Query: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL P  G  GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668
           YELQ  A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668

Query: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728
           LVESGQAP+ASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD---- 784
           EGAC+  KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP    S +    
Sbjct: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788

Query: 785 ---------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 835
                     PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE
Sbjct: 789 REEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848

Query: 836 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 895
           PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI
Sbjct: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908

Query: 896 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1504 bits (3894), Expect = 0.0
 Identities = 767/941 (81%), Positives = 826/941 (87%), Gaps = 13/941 (1%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
            R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP+FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++D
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A+ A  PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSRAS+G AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E
Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP---SSTDN- 785
           GAC+  KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL   P      +N 
Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQ 789

Query: 786 ---------PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
                    PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 790 DLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1503 bits (3892), Expect = 0.0
 Identities = 766/941 (81%), Positives = 828/941 (87%), Gaps = 13/941 (1%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR   K
Sbjct: 10  GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I +RPLQVFHV+V+VKDINDN
Sbjct: 70  THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV  S++  
Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V
Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
            L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG I +I  +D
Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA   TVI
Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD
Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGT GAV ELVPR VGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A GA IPFRVGLYTGEISTTR LDE D  R+RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSRAS+G+AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCS P +E
Sbjct: 670 VESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSVPPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD----- 784
           GA    KPTLVCSSA+GSWS SQQRRQRVCS EGPPKTDLMAFSP L    ++++     
Sbjct: 730 GAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSLNTSERNEQP 789

Query: 785 --------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
                   NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 790 EANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1497 bits (3876), Expect = 0.0
 Identities = 761/941 (80%), Positives = 815/941 (86%), Gaps = 13/941 (1%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G   LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
              DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + 
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G I + G++D
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PRVGGTGGA  +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A+   IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSR S G+ GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD----- 784
           G C   KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP    S D     
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789

Query: 785 --------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
                    PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1493 bits (3864), Expect = 0.0
 Identities = 758/934 (81%), Positives = 821/934 (87%), Gaps = 11/934 (1%)

Query: 15  LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74
           LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR   K  GDL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
            T + +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374
           +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A  GTVI LI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614
           VLDENDNAPALLAPR G   GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674
              A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734
           APKASSRA +G AG E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + 
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD---------- 784
            KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S +          
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794

Query: 785 -NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 843
             PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP
Sbjct: 795 GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 854

Query: 844 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 903
           PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF
Sbjct: 855 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 914

Query: 904 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 915 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1487 bits (3850), Expect = 0.0
 Identities = 761/941 (80%), Positives = 820/941 (87%), Gaps = 14/941 (1%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G   L L++++L  WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 10  GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN
Sbjct: 70  THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+
Sbjct: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V
Sbjct: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
            L EN +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D
Sbjct: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD
Sbjct: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV
Sbjct: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA + G  GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSR   G A PE  LVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA  +E
Sbjct: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQG---------- 779
           GAC+  KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G          
Sbjct: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGERQ 788

Query: 780 -PSST--DNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
            P S     PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 789 EPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 848

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 849 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 908

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 909 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1482 bits (3837), Expect = 0.0
 Identities = 766/941 (81%), Positives = 815/941 (86%), Gaps = 14/941 (1%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K   LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           K+ EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+S  ++I V+  DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQ  A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VE  QAPKASSRAS+G+A PE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQ----------- 778
           GAC  VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP            
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787

Query: 779 --GPSSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
             G   +  PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 788 SIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1474 bits (3817), Expect = 0.0
 Identities = 759/941 (80%), Positives = 807/941 (85%), Gaps = 6/941 (0%)

Query: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60
           ++ P G  PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV
Sbjct: 3   IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120
           PRLFR   K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L
Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
            + T   +     LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P
Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FD+  Y V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G
Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360
            I + G +DFEE+ A++I V A+DKG P +AGH  VLVEV+DVNDN P++ +TSLSLP+ 
Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360

Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G  GGAV ELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660
           SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRAS+G   PE  LVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           LRCSAP +   C+  KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL    
Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780

Query: 781 SSTDN----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836
               N    PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 781 EDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840

Query: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900

Query: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1361 bits (3522), Expect = 0.0
 Identities = 697/783 (89%), Positives = 724/783 (92%)

Query: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67
           DP G+ LLL ++ILA W  G GQLHYSVPEEA+HG FVGRIAQDLGLELAELVPRLF+  
Sbjct: 8   DPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLD 67

Query: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127
            K RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKDIN
Sbjct: 68  SKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DNPPVFPATQ+NLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ
Sbjct: 128 DNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY
Sbjct: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
           TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH
Sbjct: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367
           MDFEESRAHKIPVEAVDKGFPPLAGHCT+LVEVVDVNDNAPQLT+ +LS+P+ EDAQ GT
Sbjct: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGT 367

Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VI LISV D D   NGQVTCSLTP VPFKLVST+KNYYSLVLD ALDRESVSAYELVVTA
Sbjct: 368 VIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487

Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR+ GT GAV E+V RSVGAG VV KVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWL 607

Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667
           SYELQP  A ASIPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEP+LTATATVLV
Sbjct: 608 SYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLV 667

Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727
           SLVESGQAPK+SSRAS+G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYT LRCSA  
Sbjct: 668 SLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMP 727

Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPR 787
           +EG C+  KPTLVCSSAVGSWS+SQQRRQRVCSGEG  KTDLMAFSP L     ST+   
Sbjct: 728 TEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTG 787

Query: 788 QPN 790
           +P+
Sbjct: 788 EPS 790


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1276 bits (3302), Expect = 0.0
 Identities = 654/773 (84%), Positives = 694/773 (89%)

Query: 12  RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71
           R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR   K R
Sbjct: 12  RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71

Query: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131
           G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP
Sbjct: 72  GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131

Query: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
           VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P  ++ VK 
Sbjct: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191

Query: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
           LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L
Sbjct: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251

Query: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
            ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE
Sbjct: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311

Query: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371
           ES++++I VE +DKG  PL+GHC V+VEV D NDN P L   SLSLPI EDA  GTVI L
Sbjct: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371

Query: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV D+D GVNG VTCSLT  VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG
Sbjct: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491
           SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491

Query: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
           YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL
Sbjct: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671
           QP   GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671

Query: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731
           SGQAPKASSRA +G  GP+  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +EGA
Sbjct: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731

Query: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784
           C+  KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP      D
Sbjct: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDRED 784


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1233 bits (3190), Expect = 0.0
 Identities = 633/792 (79%), Positives = 691/792 (87%)

Query: 8   DPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAV 67
           DPG + LLL +++LAA E G GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR  
Sbjct: 8   DPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  CKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIN 127
            K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+VEVKDIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIN 127

Query: 128 DNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQ 187
           DN PVFP   +NLFI+ESR   SRF LEGASDADIG N+LLTY L   EYF LDV  +++
Sbjct: 128 DNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDE 187

Query: 188 QVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           ++K LGLVL+K L+RE+TP+ +LL+TA DGGKPELTGT QL ITVLD NDNAP F+RT+Y
Sbjct: 188 EIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIY 247

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGH 307
            V+L EN   GTLV+  NA+DLDEG+N DI YSF++D+S DI SKFH+DP++G I+V G+
Sbjct: 248 KVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGN 307

Query: 308 MDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGT 367
           +DFEES++++I VEA DKG PP++ HCTVL+E+VD+NDN P+L + SLSLP+ ED+   T
Sbjct: 308 IDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLST 367

Query: 368 VITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VI LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDS LDRESVSAYELVVTA
Sbjct: 368 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTA 427

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKN 487
           RDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+N
Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQEN 487

Query: 488 ALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547
           ALVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS
Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547

Query: 548 NVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PRVGG GGAV ELVPRSVGAGHVVAKVRAVDADSGYNAWL
Sbjct: 548 NVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607

Query: 608 SYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLV 667
           SYELQP   GA IPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEPSLTATATVLV
Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLV 667

Query: 668 SLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPS 727
           SLVESGQAPKASS+AS G  GPE  LVDVNVYLI+AICAVSSLLVLTLLLYTALRCSAP 
Sbjct: 668 SLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPP 727

Query: 728 SEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPR 787
           +EG C   KPTLVCSSAVGSWS+SQQR+QRVCSGEG PKTDLMAFSPSLP  P S D   
Sbjct: 728 TEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREE 787

Query: 788 QPNPDWRYSASL 799
           + + D   SA +
Sbjct: 788 KQDVDVDLSAKV 799


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1202 bits (3110), Expect = 0.0
 Identities = 617/784 (78%), Positives = 672/784 (85%)

Query: 9   PGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVC 68
           P  R LLL+++ILAAWE G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   
Sbjct: 9   PRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68

Query: 69  KFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDIND 128
           K  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHV+V+V+DIND
Sbjct: 69  KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIND 128

Query: 129 NPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188
           NPP+FP +++ + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF LD   S +Q
Sbjct: 129 NPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLEQ 188

Query: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248
           +  L LVLRK LDREE  E  LLLTA+DGGKPELTGTVQLLIT+LD NDNAP F +++Y 
Sbjct: 189 MSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVYK 248

Query: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308
           V + EN   GTLVI  NA+D D+G NGDI+YSF   V P +   F ++P +G I   G +
Sbjct: 249 VTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGKL 308

Query: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTV 368
           DFEE + ++I VEAVDKG  P+AGHCT+LVEV+DVNDNAP++T+TSLSLPI ED QP  +
Sbjct: 309 DFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSAI 368

Query: 369 ITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTAR 428
           I LISV DRD G NGQVTC+LTP VPFKLVST+KNYYSLVLDSALDRESVSAYELVVTAR
Sbjct: 369 IALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428

Query: 429 DGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNA 488
           DGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NA
Sbjct: 429 DGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQENA 488

Query: 489 LVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548
           LVSYSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGSN
Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGSN 548

Query: 549 VTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608
           VTLQVFVLDENDNAPALL P  G  GG V EL+PRSVGAGHVVAKVRAVDADSGYNAWLS
Sbjct: 549 VTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWLS 608

Query: 609 YELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVS 668
           YELQ  A GA IPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEP+LTATATVL+S
Sbjct: 609 YELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLLS 668

Query: 669 LVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSS 728
           LVESGQAP+ASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +
Sbjct: 669 LVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728

Query: 729 EGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQ 788
           EGAC+  KPTLVCSSA GSWS+SQQRR RVCSGEGP KTDLMAFSPSLP    S +   Q
Sbjct: 729 EGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTGQ 788

Query: 789 PNPD 792
              D
Sbjct: 789 REED 792


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 616/790 (77%), Positives = 681/790 (86%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR   K
Sbjct: 10  GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I +RPLQVFHV+V+VKDINDN
Sbjct: 70  THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV  S++  
Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V
Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
            L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG I +I  +D
Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA   TVI
Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD
Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGT GAV ELVPR VGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A GA IPFRVGLYTGEISTTR LDE D  R+RLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSRAS+G+AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCS P +E
Sbjct: 670 VESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSVPPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQP 789
           GA    KPTLVCSSA+GSWS SQQRRQRVCS EGPPKTDLMAFSP L    ++++   QP
Sbjct: 730 GAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSLNTSERNEQP 789

Query: 790 NPDWRYSASL 799
             +   S ++
Sbjct: 790 EANLDLSGNV 799


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 614/771 (79%), Positives = 672/771 (87%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
            R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP+FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++D
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLAPRVGGTGGAV ELVPRS+GAG VVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A+ A  PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSRAS+G AGPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAP +E
Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           GAC+  KPTLVCSSAVGSWS+SQQRRQRVCSGEGPPK DLMAFSPSL   P
Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1199 bits (3102), Expect = 0.0
 Identities = 615/775 (79%), Positives = 669/775 (86%)

Query: 11  GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70
           G  LLL  ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR   K 
Sbjct: 10  GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69

Query: 71  RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130
           RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP
Sbjct: 70  RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129

Query: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190
           P F   ++ LFI ESR  DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++  
Sbjct: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189

Query: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250
            L LVLRK LDREET E  LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+
Sbjct: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249

Query: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310
           L EN   GTLVI  NASD DEG+N +I+Y FS+ V  D+KSKF ++  +G I V G +D+
Sbjct: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309

Query: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370
           E+  +++I ++A+DK   PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA   TVI 
Sbjct: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369

Query: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430
           LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG
Sbjct: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429

Query: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490
           GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV
Sbjct: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489

Query: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550
           SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT
Sbjct: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549

Query: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610
           LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE
Sbjct: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609

Query: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670
           LQP    A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV
Sbjct: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669

Query: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730
           ESGQAPKASSRAS G  GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E 
Sbjct: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729

Query: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDN 785
            C+  KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDN
Sbjct: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1192 bits (3084), Expect = 0.0
 Identities = 609/775 (78%), Positives = 663/775 (85%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G   LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
              DLLEV+LQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEVKD+NDN
Sbjct: 70  RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF    + LF++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF LDV + N + 
Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K + LVLRK LDRE+ P  HL LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V   +   F +D  +G I + G++D
Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE RVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV
Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALL PRVGGTGGA  +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A+   IPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSR S G+ GPE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784
           G C   KPTLVCSSAVGSWS+SQQ+ QRVCSGEGPPKTDLMAFSP LP    S D
Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVD 784


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1187 bits (3072), Expect = 0.0
 Identities = 608/785 (77%), Positives = 674/785 (85%)

Query: 15  LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74
           LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR   K  GDL
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194
            T + +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+  +++  + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254
           VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314
            + GTLV+  NASD DEG N +I+YS  SDVS  I++KF +DP+SG I   G +D+EE++
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374
           +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A  GTVI LI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
            DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554
           VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614
           VLDENDNAPALLAPR G   GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ  
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674
              A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734
           APKASSRA +G AG E  LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + 
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWR 794
            KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S +  +    ++ 
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794

Query: 795 YSASL 799
              SL
Sbjct: 795 GKVSL 799


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1184 bits (3063), Expect = 0.0
 Identities = 608/782 (77%), Positives = 670/782 (85%), Gaps = 1/782 (0%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G   L L++++L  WE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 10  GTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCG+SAECSIHLEVIV+RPLQVFHV+VEVKDINDN
Sbjct: 70  THGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYF LD PT+ +Q+
Sbjct: 130 PPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGKQI 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K L L+L+K LDRE+TPEL+LLLTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y V
Sbjct: 190 KRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEYKV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
            L EN +  TLV+  NA+D DEG+NG++ YS  S + P+ +  F +D  +G + V G +D
Sbjct: 250 SLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGTLD 308

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           +EE++ +KI V+A DKG PP+AGHCTV VE++D NDN+P++ +TSLSLP+ EDAQP TVI
Sbjct: 309 YEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPSTVI 368

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV DRD GVNGQVTCSLTP VPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTARD
Sbjct: 369 ALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTARD 428

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 429 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 488

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE R+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL SNV
Sbjct: 489 VSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSSNV 548

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA + G  GGAV +LVPRSVGAGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQP A G+ IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSL
Sbjct: 609 ELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 668

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VESGQAPKASSR   G A PE  LVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA  +E
Sbjct: 669 VESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATPTE 728

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQP 789
           GAC+  KPTLVCS AVGSWS+SQQRRQRVCS EGPPKTDLMAFSPSLP G +  +   + 
Sbjct: 729 GACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGERQ 788

Query: 790 NP 791
            P
Sbjct: 789 EP 790


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1178 bits (3047), Expect = 0.0
 Identities = 614/771 (79%), Positives = 662/771 (85%), Gaps = 1/771 (0%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K   LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           K+ EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+S  ++I V+  DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549
           VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548

Query: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609
           TLQVFVLDENDNAPALLA   G  GGAV ELV RSV AGHVVAKVRAVDADSGYNAWLSY
Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608

Query: 610 ELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSL 669
           ELQ  A GA IPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEPSLTATATVLVSL
Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668

Query: 670 VESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSE 729
           VE  QAPKASSRAS+G+A PE  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +E
Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727

Query: 730 GACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           GAC  VKPTLVCSSAVGSWS+SQQRRQRVCSGEG PK DLMAFSPSLP  P
Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1169 bits (3023), Expect = 0.0
 Identities = 608/786 (77%), Positives = 656/786 (83%), Gaps = 2/786 (0%)

Query: 1   MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60
           ++ P G  PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV
Sbjct: 3   IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120
           PRLFR   K  GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180
           VEVKDINDNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L
Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180

Query: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240
            + T   +     LVLRKLLDRE+TP+L+LLL   DGGKPELTG+VQ+ ITVLD NDN P
Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240

Query: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300
            FD+  Y V L ENV   T VI  NASD DEGLNG+I Y     +    K  F ++P +G
Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300

Query: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360
            I + G +DFEE+ A++I V A+DKG P +AGH  VLVEV+DVNDN P++ +TSLSLP+ 
Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360

Query: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA
Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA
Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLA   G  GGAV ELVPRSVGAGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660
           SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           +TATVLVSLVE+GQAPK SSRAS+G   PE  LVD+NVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780
           LRCSAP +   C+  KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL    
Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780

Query: 781 SSTDNP 786
               NP
Sbjct: 781 EDCLNP 786


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
            [Homo sapiens]
          Length = 1007

 Score =  857 bits (2215), Expect = 0.0
 Identities = 477/991 (48%), Positives = 628/991 (63%), Gaps = 78/991 (7%)

Query: 14   LLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRA--VCKFR 71
            LLL +++L    A   QL YSVPEE   G  VG +A+ LGLEL  L P   R   +    
Sbjct: 28   LLLLLLLLLPGPAA-SQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86

Query: 72   GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131
               LE++L +G LFVN RIDRE LC +   C + LEV+   P+ V  V+VE+ DINDN P
Sbjct: 87   PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146

Query: 132  VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191
             FP     L ++ES    +RF +E A D D+G N++ TY LSP+E+F LD+    +  K 
Sbjct: 147  RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206

Query: 192  LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251
            L LVLRK LDRE+    HL+LTA DGG P  +GT Q+ + VLD NDN+P FD++ Y V+L
Sbjct: 207  LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266

Query: 252  PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311
             E+   GTLV+  NASD DEG NG++ YS SS  S   +  F +D  +G + VIG +D+E
Sbjct: 267  REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326

Query: 312  ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371
            E+ +++I V+A D+G  P+AGHC VLV++VDVNDNAP++ LT L  P+PE+A P T++ +
Sbjct: 327  EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386

Query: 372  ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
            +SV D+D G N +V+  L   +PF+L + F N Y+LV+   LDRE V+ Y + VTA DGG
Sbjct: 387  LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445

Query: 432  SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491
             P L +  ++ VE++D+NDN P+F +  Y+++++ENN PG  + TV A D D ++NA V+
Sbjct: 446  IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505

Query: 492  YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551
            YSL+E  +    ++SYVS+++ SG +YA+   D+E+       V A+D G PPL S VT 
Sbjct: 506  YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565

Query: 552  QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611
             V+V+D ND+AP +L P       A  E+VPR+  AG++V KV A+D+DSG NAWL Y L
Sbjct: 566  NVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624

Query: 612  QPVAAGASIP-FRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670
               A  + +  F+V L+TGEI TTR + +       L V+V+D+GEPSL+A+  + V++V
Sbjct: 625  ---AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVV 681

Query: 671  ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730
            +  +  K        +  P T   ++ +YLIIA+  VS + +LT+++ + ++C   ++ G
Sbjct: 682  D--RVSKILPDTQRHVKSPRT-YSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYG 738

Query: 731  -ACS------------------------------LVKPTLVCSSAVGSWSFSQQRRQRVC 759
             AC                                V+P  +     G+ S ++    + C
Sbjct: 739  TACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFI--EVRGNGSLTKTYCYKAC 796

Query: 760  SGEGPPKTDLMAFSPSLPQGPS---------------------------------STDNP 786
               G      M ++     GP                                  S + P
Sbjct: 797  LTAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEP 856

Query: 787  RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVG 846
            RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVG
Sbjct: 857  RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVG 916

Query: 847  AGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKK 906
            AGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKK
Sbjct: 917  AGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKK 976

Query: 907  EETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937
            EETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 977  EETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  786 bits (2029), Expect = 0.0
 Identities = 398/525 (75%), Positives = 450/525 (85%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G R LLL++++LAAWE G GQLHYS+PEEAKHG FVGR+AQDLGLELAELVPRLFR   K
Sbjct: 10  GARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
              DLLEVNLQNGILFVNSRIDREELC  SAECSIHLE+I +RPLQVFHV+V+VKDINDN
Sbjct: 70  THRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVEVKVKDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PPVF   ++ +FI ESR L+SRFP+EGA+DADIG NALLTY LSP++YF LDV  S++  
Sbjct: 130 PPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELS 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K L L LRK LDREETPELHLLLTATDGGKPEL GTV+LLITVLD NDNAP+FD+ +Y V
Sbjct: 190 KSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
            L E  + GTLV   NASD DEG+NG++++SF S +S DI+ KF +D  SG I +I  +D
Sbjct: 250 HLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           +EE+++++I V+AVDKG PP++ HC VLV+V+DVNDNAP+L +TSL LPI EDA   TVI
Sbjct: 310 YEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LI+V DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRES+S YELVVTARD
Sbjct: 370 ALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           VSYSLVE RVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 490 VSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  442 bits (1138), Expect = e-124
 Identities = 286/609 (46%), Positives = 340/609 (55%), Gaps = 48/609 (7%)

Query: 336 VLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPF 395
           V V+V D+NDN P        + IPE     +   +    D D G N  +T +L+P   F
Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178

Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDN 451
            L     +  S    L L   LDRE      L++TA DGG P L  T  + + V DVNDN
Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238

Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVH 511
           AP F Q  Y V + E    G  + T++A DAD   N  V +S        R +     V 
Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGI--SRDIQEKFKVD 296

Query: 512 AESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVG 571
           + SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L    V 
Sbjct: 297 SSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELA---VT 353

Query: 572 GTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGE 630
                +RE  P S     V+A +   D DSG N  ++  L P      +PF+ V  +   
Sbjct: 354 SLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNY 404

Query: 631 ISTT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAG 688
            S     ALD      + L+V  +D G PSL ATA V V + +      A ++    +  
Sbjct: 405 YSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFV 464

Query: 689 PETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLVKPTLVCSSAVGSW 748
            E      +++ + A                     A + E A  LV  +LV    VG  
Sbjct: 465 KENNPPGCHIFTVSAR-------------------DADAQENA--LVSYSLV-ERRVGER 502

Query: 749 SFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVH 808
           + S        SG+      L      L Q       PRQPNPDWRYSASLRAGMHSSVH
Sbjct: 503 ALSNYVSVHAESGKVYALQPLDHEELELLQF-----QPRQPNPDWRYSASLRAGMHSSVH 557

Query: 809 LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP 868
           LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP
Sbjct: 558 LEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGP 617

Query: 869 GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG 928
           GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG
Sbjct: 618 GELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKG 677

Query: 929 NSTTDNSDQ 937
           NSTTDNSDQ
Sbjct: 678 NSTTDNSDQ 686



 Score =  151 bits (381), Expect = 3e-36
 Identities = 133/431 (30%), Positives = 202/431 (46%), Gaps = 33/431 (7%)

Query: 194 LVLRKLLDREETPE------LHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLY 247
           L +   +DREE  +      +HL L A    +P     V+  + V D NDN PVF     
Sbjct: 84  LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVE--VKVKDINDNPPVFRGREQ 138

Query: 248 TVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSPDIKSKFHMDPLSGAI--T 303
            + +PE+  + +      A+D D G N  + Y+ S     S D+++    D LS ++   
Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS---DELSKSLWLE 195

Query: 304 VIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDA 363
           +  ++D EE+    + + A D G P L G   +L+ V+DVNDNAP        + + E  
Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255

Query: 364 QPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYS---LVLDSALDRESVSA 420
             GT++T ++  D D GVNG+V  S    +   +   FK   S   + L   LD E   +
Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKS 315

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480
           YE+ V A D GSP +     V V+V DVNDNAP  A     + ++E+ P    I  ++  
Sbjct: 316 YEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVS 375

Query: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540
           D D+  N  V+ SL+   V  + +S++ + ++    +     LD E L + +  V+ARD 
Sbjct: 376 DRDSGANGQVTCSLMP-HVPFKLVSTFKNYYS----LVLDSALDRESLSVYELVVTARDG 430

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600
           G P L +   + V V D NDNAPA   P            V  +   G  +  V A DAD
Sbjct: 431 GSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARDAD 483

Query: 601 SGYNAWLSYEL 611
           +  NA +SY L
Sbjct: 484 AQENALVSYSL 494


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  778 bits (2008), Expect = 0.0
 Identities = 401/525 (76%), Positives = 443/525 (84%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAWE G GQLHYSV EEA+HG FVGRIAQDLGLELAELV RLFR   K
Sbjct: 9   GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
             GDLLEVNLQNGILFVNSRIDREELCGRS ECSIHLEVIV+RPLQVFHVDVEVKDINDN
Sbjct: 69  RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP F  T++ L I ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF LD+     + 
Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K   LVLRKLLDREE P+L LLLTATDGGKPE TG+V LLI VLD NDNAP+FDR +Y V
Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           K+ EN    TLVI  NASD DEG+N +++YSFSS V P I+ KF ++  +G I V   +D
Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+S  ++I V+  DKG PP+ GHCTVLVE++D NDN+P++ +TSLSLP+ EDAQ GTVI
Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQVTCSLTP VPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD
Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSP LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           VSYSLVE R+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  438 bits (1126), Expect = e-122
 Identities = 276/607 (45%), Positives = 338/607 (55%), Gaps = 48/607 (7%)

Query: 338 VEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKL 397
           VEV D+NDN P+ ++T   L IPE     +   L    D D G N  +T  L+P   F L
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 398 VSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAP 453
               K     +  LVL   LDRE     +L++TA DGG P    + S+ + V D NDNAP
Sbjct: 180 DIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAP 239

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAE 513
            F +P Y V + EN      +  ++A D+D   N  + YS   L      +     ++  
Sbjct: 240 IFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLV--PPTIRRKFWINER 297

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573
           +G++     +D E+    +  V   D G PP+  + T+ V +LDENDN+P ++   +   
Sbjct: 298 TGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLP 357

Query: 574 GGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGEIS 632
                  V      G V+A +   D DSG N  ++  L P      +PF+ V  Y    S
Sbjct: 358 -------VKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYS 405

Query: 633 TT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPE 690
                ALD      + L+V  +D G P L ATA+V V + +      A +++   +   E
Sbjct: 406 LVLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKE 465

Query: 691 TELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLVKPTLVCSSAVGSWSF 750
                 +++ + A                     A + E A  LV  +LV    +G  S 
Sbjct: 466 NNPPGCHIFTVSA-------------------WDADAQENA--LVSYSLV-ERRLGERSL 503

Query: 751 SQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLE 810
           S        SG+      L      L Q       PRQPNPDWRYSASLRAGMHSSVHLE
Sbjct: 504 SSYVSVHAESGKVYALQPLDHEELELLQF-----QPRQPNPDWRYSASLRAGMHSSVHLE 558

Query: 811 EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE 870
           EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE
Sbjct: 559 EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE 618

Query: 871 LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS 930
           LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS
Sbjct: 619 LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS 678

Query: 931 TTDNSDQ 937
           TTDNSDQ
Sbjct: 679 TTDNSDQ 685



 Score =  136 bits (343), Expect = 8e-32
 Identities = 113/387 (29%), Positives = 179/387 (46%), Gaps = 18/387 (4%)

Query: 230 ITVLDNNDNAPVFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSD--VSP 287
           + V D NDN P F  T   + +PE+  + +      ASD D G N  + Y  S +     
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 288 DIKSKFHMDPLSGAITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNA 347
           DI +K   D     + +   +D EE+   K+ + A D G P   G  ++L+ V+D NDNA
Sbjct: 180 DIINKKDKDKFP-VLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNA 238

Query: 348 PQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTF---KNY 404
           P        + + E+    T++  ++  D D G+N ++  S +  VP  +   F   +  
Sbjct: 239 PIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERT 298

Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFV 464
             + ++ A+D E  + YE+ V   D G+P +    +V VE+ D NDN+P       ++ V
Sbjct: 299 GEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPV 358

Query: 465 KENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLD 524
           KE+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +     LD
Sbjct: 359 KEDAQVGTVIALISVSDHDSGANGQVTCSLTP-HVPFKLVSTYKNYYS----LVLDSALD 413

Query: 525 HEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRS 584
            E +   +  V+ARD G PPL +  ++ V V D NDNAPA                V  +
Sbjct: 414 RERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTVFVKEN 466

Query: 585 VGAGHVVAKVRAVDADSGYNAWLSYEL 611
              G  +  V A DAD+  NA +SY L
Sbjct: 467 NPPGCHIFTVSAWDADAQENALVSYSL 493


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  774 bits (1999), Expect = 0.0
 Identities = 394/525 (75%), Positives = 444/525 (84%)

Query: 10  GGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCK 69
           G + LLL +++LAAW+ G GQLHYSVPEEAKHG FVGRIAQDLGLELAELVPRLFR   K
Sbjct: 10  GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69

Query: 70  FRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDN 129
            R DLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIV+RPLQVFHVDVEV+DINDN
Sbjct: 70  DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129

Query: 130 PPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQV 189
           PP+FP  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF LDV  ++   
Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189

Query: 190 KPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTV 249
           K +GL+L+K LDREE P  +L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y V
Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249

Query: 250 KLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMD 309
           ++ EN   GT VI  NASD DEG NG I YSF+S V+  +   F +D  +G I + G++D
Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309

Query: 310 FEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVI 369
           FE+   +KI ++A DKG PP+AGHCTVLV ++D NDN P++ LTSLSLP+ EDAQ GTVI
Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369

Query: 370 TLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429
            LISV D D G NGQV CSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD
Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429

Query: 430 GGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNAL 489
           GGSPSLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL
Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489

Query: 490 VSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           VSYSLVE RVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  451 bits (1160), Expect = e-126
 Identities = 283/607 (46%), Positives = 341/607 (56%), Gaps = 48/607 (7%)

Query: 338 VEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPF-- 395
           VEV D+NDN P   +    + I E   P +V  L    D D G N  +T  L+    F  
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180

Query: 396 --KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAP 453
             K+ S       L+L  +LDRE   A+ L +TA DGG P L  T  + V V DVNDNAP
Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSLVELRVGERALSSYVSVHAE 513
            F Q EY V + EN   G  +  ++A D D   N  +SYS   L      +  + S+   
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAA--MVIDHFSIDRN 298

Query: 514 SGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRVGGT 573
           +G++     LD E+  L +  + A D G PP+  + T+ V +LD+NDN P +    +   
Sbjct: 299 TGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLP 358

Query: 574 GGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPVAAGASIPFR-VGLYTGEIS 632
              VRE        G V+A +   D DSG N  ++  L P      +PF+ V  +    S
Sbjct: 359 ---VRE----DAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYS 406

Query: 633 TT--RALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQAPKASSRASLGIAGPE 690
                ALD      + L+V  +D G PSL ATA++ V + +      A ++    +   E
Sbjct: 407 LVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKE 466

Query: 691 TELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSLVKPTLVCSSAVGSWSF 750
                 +++ + A                     A + E A  LV  +LV    VG  + 
Sbjct: 467 NNPPGCHIFTVSAR-------------------DADAQENA--LVSYSLV-ERRVGERAL 504

Query: 751 SQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPNPDWRYSASLRAGMHSSVHLE 810
           S        SG+      L      L Q       PRQPNPDWRYSASLRAGMHSSVHLE
Sbjct: 505 SSYISVHAESGKVYALQPLDHEELELLQF-----QPRQPNPDWRYSASLRAGMHSSVHLE 559

Query: 811 EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE 870
           EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE
Sbjct: 560 EAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGE 619

Query: 871 LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS 930
           LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS
Sbjct: 620 LPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNS 679

Query: 931 TTDNSDQ 937
           TTDNSDQ
Sbjct: 680 TTDNSDQ 686


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,999,815
Number of Sequences: 37866
Number of extensions: 2068019
Number of successful extensions: 14612
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 109
Number of HSP's that attempted gapping in prelim test: 7021
Number of HSP's gapped (non-prelim): 1278
length of query: 937
length of database: 18,247,518
effective HSP length: 112
effective length of query: 825
effective length of database: 14,006,526
effective search space: 11555383950
effective search space used: 11555383950
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.