BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] (936 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1852 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1538 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1534 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1532 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1529 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1517 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1516 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1513 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1511 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1501 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1487 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1484 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1477 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1463 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1228 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1227 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1226 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1214 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1214 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1207 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1199 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1196 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1184 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1181 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1174 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1157 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 815 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 789 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 785 0.0 gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 621 e-178 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1852 bits (4798), Expect = 0.0 Identities = 936/936 (100%), Positives = 936/936 (100%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 Query: 781 STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 840 STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV Sbjct: 781 STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 840 Query: 841 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 900 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI Sbjct: 841 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 900 Query: 901 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1538 bits (3982), Expect = 0.0 Identities = 784/784 (100%), Positives = 784/784 (100%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 Query: 781 STDN 784 STDN Sbjct: 781 STDN 784 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1534 bits (3972), Expect = 0.0 Identities = 783/940 (83%), Positives = 829/940 (88%), Gaps = 10/940 (1%) Query: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 Query: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 Query: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 Query: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 Query: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 Query: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 Query: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 Query: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 Query: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 Query: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD--- 783 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787 Query: 784 -------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 836 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE Sbjct: 788 TTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 847 Query: 837 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 896 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK Sbjct: 848 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 907 Query: 897 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 908 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1532 bits (3967), Expect = 0.0 Identities = 783/950 (82%), Positives = 832/950 (87%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 780 TSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 S D PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1530 bits (3960), Expect = 0.0 Identities = 781/950 (82%), Positives = 843/950 (88%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GAVSELVPR VGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA G ARIPFRVGLYTGEISTTR LDE + R+RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL-PQG 778 LRCS PTE GKPTL+CSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP L P Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 779 PTS------------TDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 TS + NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1517 bits (3928), Expect = 0.0 Identities = 774/950 (81%), Positives = 827/950 (87%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 Query: 780 TSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 IMMGKAENQDLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1516 bits (3926), Expect = 0.0 Identities = 775/950 (81%), Positives = 831/950 (87%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 780 TSTD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 S D PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1513 bits (3918), Expect = 0.0 Identities = 767/927 (82%), Positives = 821/927 (88%) Query: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 Query: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 Query: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 Query: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 Query: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 Query: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 Query: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 Query: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 Query: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNPRQPN 789 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDNPRQPN Sbjct: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNPRQPN 790 Query: 790 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 849 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN Sbjct: 791 PDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVN 850 Query: 850 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 909 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK Sbjct: 851 SNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETK 910 Query: 910 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 KKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 911 KKKKKKKGNKTQEKKEKGNSTTDNSDQ 937 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1511 bits (3912), Expect = 0.0 Identities = 769/950 (80%), Positives = 830/950 (87%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP--- 776 LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 777 -----QGPTSTDN-----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 G D+ PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1501 bits (3886), Expect = 0.0 Identities = 768/943 (81%), Positives = 819/943 (86%), Gaps = 11/943 (1%) Query: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 Query: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 Query: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 Query: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 Query: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 Query: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 Query: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 Query: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 Query: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD- 783 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785 Query: 784 ----------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 833 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP Sbjct: 786 KQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 845 Query: 834 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 893 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ Sbjct: 846 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 905 Query: 894 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 906 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1487 bits (3849), Expect = 0.0 Identities = 761/948 (80%), Positives = 818/948 (86%), Gaps = 16/948 (1%) Query: 3 YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61 + RRG LG+ L LWLLL +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R Sbjct: 4 FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62 Query: 62 LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121 LFRVASK GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V Sbjct: 63 LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122 Query: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181 VKDINDNPP FS +EQ+L I ES+ DSRFPLEGASD DI NA L YRL+ NEYF LD Sbjct: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182 Query: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241 TN ++ L L+L+KSLDRE+T E LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF Sbjct: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242 Query: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301 DKS Y V L+ENA TLV+KLNA+D DEG+N E+ Y + + + + F ++ N GE+ Sbjct: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301 Query: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361 +VNG LDYE+ Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED Sbjct: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361 Query: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421 A STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V YE Sbjct: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421 Query: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481 LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA Sbjct: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481 Query: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541 DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV Sbjct: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541 Query: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601 PPL SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVD DSG Sbjct: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601 Query: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661 YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT Sbjct: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661 Query: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721 ATVLVSLVESGQAPKASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL Sbjct: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721 Query: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTS 781 SA PTE C GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G Sbjct: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNK 781 Query: 782 TD-------------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 828 + PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV Sbjct: 782 EEEGERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 841 Query: 829 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 888 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE Sbjct: 842 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 901 Query: 889 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 902 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1484 bits (3842), Expect = 0.0 Identities = 766/950 (80%), Positives = 821/950 (86%), Gaps = 14/950 (1%) Query: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLP--Q 777 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 778 GPT-----------STDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 826 G T ST PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 827 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 886 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 887 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1478 bits (3825), Expect = 0.0 Identities = 764/947 (80%), Positives = 817/947 (86%), Gaps = 15/947 (1%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542 Query: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602 PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY Sbjct: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602 Query: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662 NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA Sbjct: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662 Query: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722 TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721 Query: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQ----- 777 SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP Sbjct: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVD 781 Query: 778 --------GPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 829 G + PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS Sbjct: 782 VDGEDQSIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 841 Query: 830 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 889 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP Sbjct: 842 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 901 Query: 890 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 902 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1463 bits (3787), Expect = 0.0 Identities = 751/940 (79%), Positives = 810/940 (86%), Gaps = 4/940 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 Query: 781 STDN----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 836 N PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE Sbjct: 782 DCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 841 Query: 837 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 896 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK Sbjct: 842 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 901 Query: 897 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 902 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1228 bits (3177), Expect = 0.0 Identities = 631/777 (81%), Positives = 677/777 (87%) Query: 7 GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66 G RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 67 SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126 SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186 DNPP F ++ L I ESR DSRFPLEGASD DIG NA L YRL+PNEYF L+ ++E Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187 Query: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246 L L+LRKSLDREE E L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY Sbjct: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247 Query: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306 VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN + +VKSKF I+ TG+I V G Sbjct: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307 Query: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366 +D+E+ SYEI ++ +DK PLSGHC+V+V++ D NDN P++ +L LP++EDAPL T Sbjct: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367 Query: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426 VIALISVSD+D G NG VTCSL HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA Sbjct: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486 RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN Sbjct: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487 Query: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546 ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547 Query: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606 NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607 Query: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666 SYELQP G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV Sbjct: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667 Query: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726 SLVESGQAPKASSRA GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P Sbjct: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727 Query: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783 TE C GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP D Sbjct: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDRED 784 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1227 bits (3175), Expect = 0.0 Identities = 631/784 (80%), Positives = 680/784 (86%), Gaps = 1/784 (0%) Query: 1 MVYSRRGSLGS-RLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M Y RG LGS RLLLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEV+LQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKD+NDNPP F ++Q+LF+ ESRMPDSRFPLEGASD D+GAN+ L YRL+ ++YF L Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV + +E +ELVLRKSLDRE+ H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VIKLNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRE VS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGA S+LVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA S RIPFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSR SAG +GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP LP Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780 Query: 780 TSTD 783 S D Sbjct: 781 GSVD 784 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1226 bits (3173), Expect = 0.0 Identities = 628/799 (78%), Positives = 695/799 (86%), Gaps = 1/799 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGT GAVSELVPR VGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQPA G ARIPFRVGLYTGEISTTR LDE + R+RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS G GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCS PTE GKPTL+CSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP L Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 780 TSTDNPRQPNPDWRYSASL 798 +++ QP + S ++ Sbjct: 781 NTSERNEQPEANLDLSGNV 799 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1214 bits (3141), Expect = 0.0 Identities = 626/799 (78%), Positives = 685/799 (85%), Gaps = 1/799 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M++S R G++ LLL LLLA + GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDN P F + LFI ESR P SRF LEGASD DIG N+ L Y L+ EYF L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N+EE L LVL+K+L+RE+T +H LL+ A DGGKPELTGT QL I VLD NDNAP Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F+++IY VRLLENAP+GTLV+ +NA+D DEG+NK+I Y F+ + D+ SKF ++ G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 +I V G +D+E+ SYEI ++A DK P+S HC V+++++D+NDN PE+ I +L LPV Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED+PLSTVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDS LDRESVS Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL+PRVGG GGAVSELVPRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP G ARIPFRVGLYTGEISTTR+LDE +APRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASS+ASAGA GPEAALVDVNVYLI+AICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSLP P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 780 TSTDNPRQPNPDWRYSASL 798 S D + + D SA + Sbjct: 781 ISRDREEKQDVDVDLSAKV 799 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1214 bits (3140), Expect = 0.0 Identities = 622/780 (79%), Positives = 675/780 (86%), Gaps = 1/780 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PRVGGTGGAVSELVPRS+GAG VVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SAR PFRVGLYTGEISTTR LDE ++PRHRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPKASSRAS GA GPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE CT KPTL+CSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSL P Sbjct: 721 LRCSAPPTEGACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCP 780 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1207 bits (3124), Expect = 0.0 Identities = 618/792 (78%), Positives = 679/792 (85%), Gaps = 1/792 (0%) Query: 1 MVYSRRGSLGSRLLLLWLL-LAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+ S +G R LLLWLL LA W+ GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK GDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F ++R+ I ESR P++RFPL+GASD DIG N+ L YRL+PN+YF L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 D + + E+ + L LVLRK+LDREE QEH LL+ A+DGGKPELTGTVQLLI +LD NDNAP Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 EF +S+Y V +LENA +GTLVIKLNA+D D+G N +IVY F V V F IN N G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI+ G+LD+E+ YEI+++A+DK P++GHC ++V++LDVNDN PE+ IT+L LP++ Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 ED S +IALISVSDRDSG+NGQVTC+L PHVPFKLVST+KNYYSLVLDSALDRESVS Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATASVSV VADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA+ Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL P G GG VSEL+PRSVGAGHVVAKVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQ A ARIPFRVGLYTGEISTTR LDE +AP HRLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVL+SLVESGQAP+ASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSLP Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 780 TSTDNPRQPNPD 791 S + Q D Sbjct: 781 GSAEGTGQREED 792 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1199 bits (3102), Expect = 0.0 Identities = 615/775 (79%), Positives = 669/775 (86%) Query: 10 GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKG 69 G LLL ++LA W+AG GQLHYS+PEEAKHG FVGRIAQDLGLELAELVPRLFR K Sbjct: 11 GRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKF 70 Query: 70 RGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNP 129 RGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIV+RPLQVFHV+V VKDINDNP Sbjct: 71 RGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNP 130 Query: 130 PRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETN 189 P F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF LDV T+ ++ Sbjct: 131 PVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVK 190 Query: 190 FLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVR 249 L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP FD+++Y V+ Sbjct: 191 PLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVK 250 Query: 250 LLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDY 309 L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G I V G +D+ Sbjct: 251 LPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDF 310 Query: 310 EDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIA 369 E+ +++I ++A+DK PL+GHC V+V+++DVNDN P++ +T+L LP+ EDA TVI Sbjct: 311 EESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVIT 370 Query: 370 LISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDG 429 LISV DRD G NGQVTCSL P VPFKLVSTFKNYYSLVLDSALDRESVS YELVVTARDG Sbjct: 371 LISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDG 430 Query: 430 GSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALV 489 GSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ+NALV Sbjct: 431 GSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALV 490 Query: 490 SYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVT 549 SYSLVE RVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVT Sbjct: 491 SYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVT 550 Query: 550 LQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYE 609 LQVFVLDENDNAPALL PRVGGTGGAV ELVPRSVGAGHVVAKVRAVD DSGYNAWLSYE Sbjct: 551 LQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYE 610 Query: 610 LQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLV 669 LQP A IPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLVSLV Sbjct: 611 LQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLV 670 Query: 670 ESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEA 729 ESGQAPKASSRAS G GPE LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA +E Sbjct: 671 ESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEG 730 Query: 730 VCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784 C+ KPTL+CSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSLPQGP+STDN Sbjct: 731 ACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDN 785 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1196 bits (3094), Expect = 0.0 Identities = 618/794 (77%), Positives = 672/794 (84%) Query: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 Query: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 Query: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 Query: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 Query: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 Query: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 Query: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 Query: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 Query: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 Query: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDN 784 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785 Query: 785 PRQPNPDWRYSASL 798 + ++ SL Sbjct: 786 KQLSESEYVGKVSL 799 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1184 bits (3062), Expect = 0.0 Identities = 610/789 (77%), Positives = 668/789 (84%), Gaps = 3/789 (0%) Query: 3 YSRRGSLGSRLLLLWLLLA-YWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPR 61 + RRG LG+ L LWLLL +W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELV R Sbjct: 4 FQRRG-LGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQR 62 Query: 62 LFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVA 121 LFRVASK GDLLEVNLQNGILFVNSRIDREELC + AECSIHLEVIVDRPLQVFHV V Sbjct: 63 LFRVASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVE 122 Query: 122 VKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDV 181 VKDINDNPP FS +EQ+L I ES+ DSRFPLEGASD DI NA L YRL+ NEYF LD Sbjct: 123 VKDINDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDS 182 Query: 182 KTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEF 241 TN ++ L L+L+KSLDRE+T E LL+ ATDGGKPELTGTV+LL+ VLD NDN PEF Sbjct: 183 PTNGKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEF 242 Query: 242 DKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEI 301 DKS Y V L+ENA TLV+KLNA+D DEG+N E+ Y + + + + F ++ N GE+ Sbjct: 243 DKSEYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEV 301 Query: 302 KVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKED 361 +VNG LDYE+ Y+I + A DK T P++GHC V V++LD NDN+PE+A+T+L LPV+ED Sbjct: 302 RVNGTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVRED 361 Query: 362 APLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYE 421 A STVIALISVSDRDSG NGQVTCSL PHVPFKLVSTFKNYYSLVLDSALDRE+V YE Sbjct: 362 AQPSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYE 421 Query: 422 LVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDA 481 LVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSARDA Sbjct: 422 LVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDA 481 Query: 482 DAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 541 DAQENALVSYSLVERR+G+R LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGV Sbjct: 482 DAQENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGV 541 Query: 542 PPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSG 601 PPL SNVTLQVFVLDENDNAPALL + G GGAV++LVPRSVGAGHVVAKVRAVD DSG Sbjct: 542 PPLSSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSG 601 Query: 602 YNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTAT 661 YNAWLSYELQPA G +RIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTAT Sbjct: 602 YNAWLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTAT 661 Query: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721 ATVLVSLVESGQAPKASSR AGA PEAALVDVNVYLIIAIC VSSLLVLTLLLYTAL Sbjct: 662 ATVLVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALW 721 Query: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTS 781 SA PTE C GKPTL+CS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSLP G Sbjct: 722 WSATPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNK 781 Query: 782 TDNPRQPNP 790 + + P Sbjct: 782 EEEGERQEP 790 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1181 bits (3055), Expect = 0.0 Identities = 613/790 (77%), Positives = 671/790 (84%), Gaps = 1/790 (0%) Query: 1 MVYSRRGSL-GSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 M+YS RG G LLL L+LA W GSGQLHYS+PEEA+HGTFVGRIAQDLGLELAELV Sbjct: 1 MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLF++ SKGRGDLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F ++ LFI ESR DSRFPLEGASD DIG NA L YRL+PNEYF L Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV T+ ++ L LVLRK LDREET E LL+ ATDGGKPELTGTVQLLI VLD NDNAP Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V+L EN GTLVI NASD DEG+N +I+Y FS+ V D+KSKF ++ +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 I V G +D+E+ +++I ++A+DK PL+GHC ++V+++DVNDN P++ I TL +PVK Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA L TVIALISV D D+ ANGQVTCSL PHVPFKLVST+KNYYSLVLD ALDRESVS Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 539 DADAQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 540 GVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPD 599 GVPPLGSNVTLQVFVLDENDNAPALL PR+ GT GAVSE+V RSVGAG VV KVRAVD D Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600 Query: 600 SGYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLT 659 SGYNAWLSYELQP SA IPFRVGLYTGEISTTR+LDET+APR RLLVLVKDHGEP LT Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660 Query: 660 ATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 719 ATATVLVSLVESGQAPK+SSRAS GA GPE LVDVNVYLIIAICAVSSLLVLTLLLYT Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720 Query: 720 LRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 LRCSA PTE C GKPTL+CSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP L Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780 Query: 780 TSTDNPRQPN 789 ST+ +P+ Sbjct: 781 GSTERTGEPS 790 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1174 bits (3036), Expect = 0.0 Identities = 612/777 (78%), Positives = 664/777 (85%), Gaps = 2/777 (0%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVP 542 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVP Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVP 542 Query: 543 PLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGY 602 PLGSN+TLQVFVLDENDNAPALL G GGAVSELV RSV AGHVVAKVRAVD DSGY Sbjct: 543 PLGSNLTLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGY 602 Query: 603 NAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATA 662 NAWLSYELQ A ARIPFRVGLYTGEISTTR+LDET++PR RLLVLVKDHGEP LTATA Sbjct: 603 NAWLSYELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATA 662 Query: 663 TVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 722 TVLVSLVE QAPKASSRAS G V PE ALVDVNVYLIIAICAVSSLLVLTLLLYTALRC Sbjct: 663 TVLVSLVEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 721 Query: 723 SAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGP 779 SA PTE C KPTL+CSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSLP P Sbjct: 722 SAAPTEGACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1157 bits (2993), Expect = 0.0 Identities = 600/785 (76%), Positives = 659/785 (83%) Query: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 Query: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 Query: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 Query: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 Query: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 Query: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 Query: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 Query: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 Query: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 Query: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 Query: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 Query: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 Query: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 Query: 781 STDNP 785 NP Sbjct: 782 DCLNP 786 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 815 bits (2106), Expect = 0.0 Identities = 412/534 (77%), Positives = 469/534 (87%), Gaps = 1/534 (0%) Query: 1 MVYSRRGSLGSRLLLLWLLL-AYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV+SRRG LG+R LLLWLLL A W+ GSGQLHYSIPEEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFRVASK DLLEVNLQNGILFVNSRIDREELC+ AECSIHLE+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V VKDINDNPP F +EQ +FI ESR+ +SRFP+EGA+D DIGANA L Y L+P++YF L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DV+ ++E + L L LRK LDREET E LL+ ATDGGKPEL GTV+LLI VLD NDNAP Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 FD+++Y V LLE +GTLV LNASDADEG+N E+V+ F + + D++ KF ++S++G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI++ +LDYE+ SYEI + A+DK + P+S HCKV+VK+LDVNDN PE+A+T+L+LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDAPLSTVIALI+VSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRES+SV Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 DADAQENALVSYSLVERRVGER LS+YVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 439 bits (1129), Expect = e-123 Identities = 289/655 (44%), Positives = 358/655 (54%), Gaps = 57/655 (8%) Query: 294 INSNTGEIKVNGELDYEDYNSY--EINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAI 351 +N G + VN +D E+ + E +I + PL V VK+ D+NDN P Sbjct: 77 VNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVF-HVEVKVKDINDNPPVFRG 135 Query: 352 TTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYS----LV 407 + + E L++ + +D D GAN +T +L P F L + S L Sbjct: 136 REQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLE 195 Query: 408 LDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENN 467 L LDRE L++TA DGG P L T + + V DVNDNAP F Q Y V + E Sbjct: 196 LRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETT 255 Query: 468 PPGCHIFTVSARDADAQENALVSYSL---VERRVGERPLSSYVSVHAESGKVYALQPLDH 524 G + T++A DAD N V +S + R + E+ V + SG++ + LD+ Sbjct: 256 ANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKVDSSSGEIRLIDKLDY 310 Query: 525 EEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSV 584 EE + + QV A D G PP+ ++ + V VLD NDNAP L V + + E P S Sbjct: 311 EETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLP---IREDAPLST 367 Query: 585 GAGHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEA 641 V+A + D DSG N ++ L P +PF+ V + S +LD Sbjct: 368 ----VIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNYYSLVLDSALDRESL 418 Query: 642 PRHRLLVLVKDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLII 701 + L+V +D G P L ATA V V + + A ++ E +++ + Sbjct: 419 SVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVS 478 Query: 702 AICAVSSLLVLTLLLYTALRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGE 761 A A + AL + V R + A Y+ Q Sbjct: 479 ARDADAQ--------ENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDH----- 525 Query: 762 APPKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 821 + +L+ F P RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP Sbjct: 526 --EELELLQFQP------------RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 571 Query: 822 DQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPA 881 DQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPA Sbjct: 572 DQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPA 631 Query: 882 IISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 IISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 632 IISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 125 bits (315), Expect = 1e-28 Identities = 116/420 (27%), Positives = 189/420 (45%), Gaps = 21/420 (5%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFS--NLVLD 286 + V D NDN P F + + E+ + A+DAD G N + Y S + Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 287 DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNT 346 DV++ ++ + +++ LD E+ + + A D L G ++++ +LDVNDN Sbjct: 181 DVEASDELSKSLW-LELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNA 239 Query: 347 PEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYS- 405 P + + E T++ ++ SD D G NG+V S + + FK S Sbjct: 240 PLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSS 299 Query: 406 --LVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFV 463 + L LD E YE+ V A D GSP + V V+V DVNDNAP A + + Sbjct: 300 GEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPI 359 Query: 464 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLD 523 +E+ P I ++ D D+ N V+ SL+ V + +S++ + ++ + LD Sbjct: 360 REDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 524 HEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRS 583 E + + + V+ARD G P L + + V V D NDNAPA P + V + Sbjct: 415 RESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKEN 467 Query: 584 VGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRSLDETE 640 G + V A D D+ NA +SY L + G + V ++ +G++ + LD E Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEE 527 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 789 bits (2037), Expect = 0.0 Identities = 402/534 (75%), Positives = 451/534 (84%), Gaps = 1/534 (0%) Query: 1 MVYSRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELV 59 MV++ LG + LLL LLLA WK GSGQLHYS+PEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVFTPEDRLGKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 60 PRLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVE 119 PRLFR+ASK R DLLEVNLQNGILFVNSRIDREELC R AECSIHLEVIVDRPLQVFHV+ Sbjct: 61 PRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 120 VAVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDL 179 V V+DINDNPP F +EQR+ I ESR+PDS FPLEGASD D+G+N+ L Y+L+ +EYF L Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 180 DVKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAP 239 DVK N ++ + L+L+KSLDREE H L + ATDGGKPELTGTVQLL+ VLD NDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 240 EFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTG 299 F++S Y VR+ ENA +GT VI+LNASD DEG N I Y F++LV V F I+ NTG Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTG 300 Query: 300 EIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVK 359 EI + G LD+E N Y+I IDA DK P++GHC V+V++LD NDN PE+A+T+L LPV+ Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360 Query: 360 EDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSV 419 EDA TVIALISV+D DSGANGQV CSL PHVPFKLVSTFKNYYSLVLDSALDRESVS Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 420 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSAR 479 YELVVTARDGGSPSLWATAS+SVEVAD+NDNAPAFAQP+YTVFVKENNPPGCHIFTVSAR Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 480 DADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 DADAQENALVSYSLVERRVGER LSSY+SVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 442 bits (1138), Expect = e-124 Identities = 291/695 (41%), Positives = 371/695 (53%), Gaps = 55/695 (7%) Query: 252 ENAPSGTLVIKLNASDADEGIN-KEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYE 310 E A GT V ++ D G+ E+V + D + +N G + VN +D E Sbjct: 37 EEAKHGTFVGRIAQ---DLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDRE 93 Query: 311 DY--NSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVI 368 + S E +I PL V V++ D+NDN P + + + E +V Sbjct: 94 ELCGRSAECSIHLEVIVDRPLQVF-HVDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVF 152 Query: 369 ALISVSDRDSGANGQVTCSLMPHVPF----KLVSTFKNYYSLVLDSALDRESVSVYELVV 424 L SD D G+N +T L F K+ S L+L +LDRE + L + Sbjct: 153 PLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFL 212 Query: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 TA DGG P L T + V V DVNDNAP F Q +Y V + EN G + ++A D D Sbjct: 213 TATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEG 272 Query: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 N +SYS + + + S+ +G++ LD E+ L + + A D G PP+ Sbjct: 273 ANGAISYSF--NSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPM 330 Query: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 + T+ V +LD+NDN P + + ++S V G V+A + D DSG N Sbjct: 331 AGHCTVLVRILDKNDNVPEIALT-------SLSLPVREDAQFGTVIALISVNDLDSGANG 383 Query: 605 WLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEAPRHRLLVLVKDHGEPPLTAT 661 ++ L P +PF+ V + S +LD + L+V +D G P L AT Sbjct: 384 QVNCSLTP-----HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWAT 438 Query: 662 ATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALR 721 A++ V + + A ++ E +++ + A A + AL Sbjct: 439 ASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ--------ENALV 490 Query: 722 CSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTS 781 + V R + + A Y+ Q + +L+ F P Sbjct: 491 SYSLVERRVGERALSSYISVHAESGKVYALQPLDH-------EELELLQFQP-------- 535 Query: 782 TDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVS 841 RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVS Sbjct: 536 ----RQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVS 591 Query: 842 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT 901 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT Sbjct: 592 PPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFIT 651 Query: 902 FGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 FGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 652 FGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 145 bits (367), Expect = 1e-34 Identities = 121/420 (28%), Positives = 196/420 (46%), Gaps = 21/420 (5%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLD-- 286 + V D NDN P F V + E+ ++ ASDAD G N + Y S+ Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 287 DVKSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNT 346 DVK N G + + LD E+ ++ + + A D L+G +++V +LDVNDN Sbjct: 181 DVKINSDDNKQIG-LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239 Query: 347 PEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTF---KNY 403 P + + + E+A T + ++ SDRD GANG ++ S V ++ F +N Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNT 299 Query: 404 YSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFV 463 +V+ LD E ++Y++++ A D G P + +V V + D NDN P A ++ V Sbjct: 300 GEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPV 359 Query: 464 KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLD 523 +E+ G I +S D D+ N V+ SL V + +S++ + ++ + LD Sbjct: 360 REDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALD 414 Query: 524 HEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRS 583 E V + V+ARD G P L + +L V V D NDNAPA P + V + Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKEN 467 Query: 584 VGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRSLDETE 640 G + V A D D+ NA +SY L + G + + ++ +G++ + LD E Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEE 527 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 785 bits (2027), Expect = 0.0 Identities = 404/531 (76%), Positives = 451/531 (84%), Gaps = 1/531 (0%) Query: 4 SRRGSLGSRLLLL-WLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRL 62 SR LG + LLL LLLA W+ GSGQLHYS+ EEA+HGTFVGRIAQDLGLELAELV RL Sbjct: 3 SRCSCLGVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRL 62 Query: 63 FRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAV 122 FRVASK GDLLEVNLQNGILFVNSRIDREELC R ECSIHLEVIVDRPLQVFHV+V V Sbjct: 63 FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEV 122 Query: 123 KDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVK 182 KDINDNPPRFS EQ+L I ESR+ DSRFPLEGASD D+G NA L Y+L+PNEYF LD+ Sbjct: 123 KDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDII 182 Query: 183 TNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFD 242 +++ F LVLRK LDREE + +LL+ ATDGGKPE TG+V LLI VLDANDNAP FD Sbjct: 183 NKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFD 242 Query: 243 KSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIK 302 + +Y V++ EN + TLVI+LNASD+DEGINKE++Y FS+LV ++ KF IN TGEIK Sbjct: 243 RPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIK 302 Query: 303 VNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDA 362 VN +D+ED N+YEI++D DK P+ GHC V+V+LLD NDN+PE+ +T+L LPVKEDA Sbjct: 303 VNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDA 362 Query: 363 PLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYEL 422 + TVIALISVSD DSGANGQVTCSL PHVPFKLVST+KNYYSLVLDSALDRE VS YEL Sbjct: 363 QVGTVIALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYEL 422 Query: 423 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDAD 482 VVTARDGGSP LWATASVSVEVADVNDNAPAFAQ +YTVFVKENNPPGCHIFTVSA DAD Sbjct: 423 VVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDAD 482 Query: 483 AQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQ 533 AQENALVSYSLVERR+GER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 483 AQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 439 bits (1129), Expect = e-123 Identities = 286/653 (43%), Positives = 354/653 (54%), Gaps = 53/653 (8%) Query: 294 INSNTGEIKVNGELDYEDY--NSYEINIDAMDKSTFPLSG-HCKVVVKLLDVNDNTPEMA 350 +N G + VN +D E+ S E +I PL H V VK D+NDN P + Sbjct: 76 VNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVK--DINDNPPRFS 133 Query: 351 ITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKN----YYSL 406 +T L + E L + L SD D G N +T L P+ F L K + L Sbjct: 134 VTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPVL 193 Query: 407 VLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKEN 466 VL LDRE +L++TA DGG P + S+ + V D NDNAP F +P Y V + EN Sbjct: 194 VLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYEN 253 Query: 467 NPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEE 526 + ++A D+D N + YS + + ++ +G++ +D E+ Sbjct: 254 QVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDAIDFED 311 Query: 527 VELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGA 586 + V D G PP+ + T+ V +LDENDN+P ++V ++S V Sbjct: 312 SNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVKEDAQV 364 Query: 587 GHVVAKVRAVDPDSGYNAWLSYELQPAPGSARIPFR-VGLYTGEISTT--RSLDETEAPR 643 G V+A + D DSG N ++ L P +PF+ V Y S +LD Sbjct: 365 GTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSLVLDSALDRERVSA 419 Query: 644 HRLLVLVKDHGEPPLTATATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAI 703 + L+V +D G PPL ATA+V V + + A +++ E +++ + Sbjct: 420 YELVVTARDGGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTV--- 476 Query: 704 CAVSSLLVLTLLLYTALRCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAP 763 +A AQ V L +G S S SG+ Sbjct: 477 --------------SAWDADAQENALVSYS-----LVERRLGERSLSSYVSVHAESGKVY 517 Query: 764 PKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ 823 L L Q PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ Sbjct: 518 ALQPLDHEELELLQF-----QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ 572 Query: 824 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII 883 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII Sbjct: 573 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII 632 Query: 884 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 633 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 685 Score = 124 bits (311), Expect = 4e-28 Identities = 116/425 (27%), Positives = 189/425 (44%), Gaps = 31/425 (7%) Query: 229 INVLDANDNAPEFDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSN---LVL 285 + V D NDN P F + + + E+ + ASDAD G N + Y S VL Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179 Query: 286 DDV----KSKFIINSNTGEIKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLD 341 D + K KF + + + LD E+ ++ + A D +G +++ +LD Sbjct: 180 DIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233 Query: 342 VNDNTPEMAITTLFLPVKEDAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTF- 400 NDN P + + E+ T++ ++ SD D G N ++ S VP + F Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293 Query: 401 --KNYYSLVLDSALDRESVSVYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQ 458 + + ++ A+D E + YE+ V D G+P + +V VE+ D NDN+P Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353 Query: 459 YTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYA 518 ++ VKE+ G I +S D D+ N V+ SL V + +S+Y + ++ + Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408 Query: 519 LQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSE 578 LD E V + V+ARD G PPL + ++ V V D NDNAPA + Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461 Query: 579 LVPRSVGAGHVVAKVRAVDPDSGYNAWLSYEL-QPAPGSARIPFRVGLY--TGEISTTRS 635 V + G + V A D D+ NA +SY L + G + V ++ +G++ + Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQP 521 Query: 636 LDETE 640 LD E Sbjct: 522 LDHEE 526 >gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor [Homo sapiens] Length = 1007 Score = 621 bits (1602), Expect = e-178 Identities = 383/1001 (38%), Positives = 548/1001 (54%), Gaps = 98/1001 (9%) Query: 13 LLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGD 72 LLLL LLL A S QL YS+PEE G VG +A+ LGLEL L P R+ G Sbjct: 28 LLLLLLLLLPGPAAS-QLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86 Query: 73 --LLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDINDNPP 130 LE++L +G LFVN RIDRE LC +R C + LEV+ P+ V VEV + DINDN P Sbjct: 87 PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146 Query: 131 RFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEEETNF 190 RF R +L + ES P +RF +E A D D+GAN+ Y L+P+E+F+LD+K +E + Sbjct: 147 RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206 Query: 191 LELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIYNVRL 250 LELVLRK LDRE+ H L++ A DGG P +GT Q+ + VLD NDN+P FD+S Y V+L Sbjct: 207 LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266 Query: 251 LENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGELDYE 310 E++P GTLV+KLNASD DEG N E+ Y S+ D + F I+++TGE++V G LDYE Sbjct: 267 REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326 Query: 311 DYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLSTVIAL 370 + +SY+I + A D+ P++GHCKV+V ++DVNDN PE+ +T L+ PV E+A +T++A+ Sbjct: 327 EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386 Query: 371 ISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTARDGG 430 +SV+D+DSG N +V+ L +PF+L + F N Y+LV+ LDRE V+VY + VTA DGG Sbjct: 387 LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445 Query: 431 SPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQENALVS 490 P L + ++ VE++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA V+ Sbjct: 446 IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505 Query: 491 YSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTL 550 YSL+ER + P++SYVS+++ SG +YA+ D+E+ V A+D G PPL S VT Sbjct: 506 YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565 Query: 551 QVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWLSYEL 610 V+V+D ND+AP +L P A E+VPR+ AG++V KV A+D DSG NAWL Y L Sbjct: 566 NVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624 Query: 611 QPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLVSLVE 670 A S F+V L+TGEI TTR + + L V+V+D+GEP L+A+ + V++V+ Sbjct: 625 --AQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682 Query: 671 SGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQPTEAV 730 + K P ++ +YLIIA+ VS + +LT+++ + ++C Sbjct: 683 --RVSKILPDTQRHVKSPR-TYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGT 739 Query: 731 CTRG--------KPTLLCSSA---------------------VGSWSYSQQRRQRVCSGE 761 G P L A G+ S ++ + C Sbjct: 740 ACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTA 799 Query: 762 APPKTDLMAFSPSLPQGPTSTDNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGP 821 M ++ GP + + + + L+ + + P P Sbjct: 800 GSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQP 859 Query: 822 DQQWPTVSSATPEPEAGEVSPPVGAGVNSN-----SWTFKYGPGNPKQSGP--------- 867 + W S + AG++S+ + + GPG P Q P Sbjct: 860 NPDW-------------RYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 906 Query: 868 --GELPDKF------------IIPGSPAIISIRQEPTNSQIDKSDFITFGKKEET----- 908 GE+ PG+P + P I S I ++E T Sbjct: 907 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 966 Query: 909 --------KKKKKK-----KKGNKTQEKKEKGNSTTDNSDQ 936 KK++ K KKGNKTQEKKEKGNSTTDNSDQ Sbjct: 967 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.133 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,605,341 Number of Sequences: 37866 Number of extensions: 1956231 Number of successful extensions: 14691 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 213 Number of HSP's successfully gapped in prelim test: 108 Number of HSP's that attempted gapping in prelim test: 7088 Number of HSP's gapped (non-prelim): 1262 length of query: 936 length of database: 18,247,518 effective HSP length: 112 effective length of query: 824 effective length of database: 14,006,526 effective search space: 11541377424 effective search space used: 11541377424 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.