Search of human proteins with 9256588

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo
sapiens]
         (947 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]  1875   0.0  
gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]  1586   0.0  
gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]  1582   0.0  
gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi...  1573   0.0  
gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi...  1561   0.0  
gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]  1548   0.0  
gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi...  1541   0.0  
gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]  1534   0.0  
gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]  1523   0.0  
gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]  1520   0.0  
gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]  1516   0.0  
gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi...  1509   0.0  
gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi...  1494   0.0  
gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi...  1489   0.0  
gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi...  1276   0.0  
gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi...  1272   0.0  
gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]  1259   0.0  
gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi...  1236   0.0  
gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap...  1229   0.0  
gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi...  1228   0.0  
gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi...  1211   0.0  
gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi...  1209   0.0  
gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi...  1206   0.0  
gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap...  1202   0.0  
gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap...  1184   0.0  
gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap...  1180   0.0  
gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso...   863   0.0  
gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi...   793   0.0  
gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi...   786   0.0  
gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap...   785   0.0  

>gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens]
          Length = 947

 Score = 1875 bits (4858), Expect = 0.0
 Identities = 947/947 (100%), Positives = 947/947 (100%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
           AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780
           LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780

Query: 781 DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 840
           DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS
Sbjct: 781 DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 840

Query: 841 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 900
           SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP
Sbjct: 841 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 900

Query: 901 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947


>gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1586 bits (4107), Expect = 0.0
 Identities = 807/950 (84%), Positives = 857/950 (90%), Gaps = 3/950 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M FSW     ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+DINDN PVFP   KNL I+ESR   SRF LEGASDADIG N+LLTY L   EYF+L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +   +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
           AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           QI VKG IDFEESKSYEI VE  DKG  P+S HC V++E+ D NDNVP+L  +SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+A  GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778
           LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP   
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 779 -SRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 837
            SRDRE++     +  AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840

Query: 838 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 897
           TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900

Query: 898 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens]
          Length = 937

 Score = 1582 bits (4097), Expect = 0.0
 Identities = 806/936 (86%), Positives = 846/936 (90%), Gaps = 10/936 (1%)

Query: 12  RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71
           R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR   K R
Sbjct: 12  RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71

Query: 72  GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131
           G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP
Sbjct: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131

Query: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191
           VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P  ++ VK 
Sbjct: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191

Query: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251
           LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251

Query: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311
            ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311

Query: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371
           ES++++I VE +DKG  PL+GHC V+VEV D NDN P L   SLSLPI EDA  GTVI L
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371

Query: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV D+D GVNG VTCSLT  VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG
Sbjct: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491
           SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491

Query: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551
           YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL
Sbjct: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671
           QP   GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671

Query: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731
           SGQAPKASSRA +G  GP+  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +EGA
Sbjct: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEE 791
           C+  KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP      D       
Sbjct: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD------- 784

Query: 792 SFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 851
               PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV
Sbjct: 785 ---NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 841

Query: 852 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 911
           SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI
Sbjct: 842 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 901

Query: 912 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 902 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937


>gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1573 bits (4074), Expect = 0.0
 Identities = 802/950 (84%), Positives = 852/950 (89%), Gaps = 3/950 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M +S     E + LLL LL+LA W  G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           + P  ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            FDRT+Y V+L ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
            I V G++DFEES++++I VE +DKG  PL+GHC ++VEV D NDN P L  K+LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA LGTVIALISV D D   NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR  GT GAVSE+V  SVG G VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPK+SSRA VGA GP+  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777
           LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG  KTDLMAFSP L    
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 778 DSRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 837
            S +R  +   + +S  KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 GSTERTGEPSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840

Query: 838 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 897
           TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900

Query: 898 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo
           sapiens]
          Length = 798

 Score = 1561 bits (4042), Expect = 0.0
 Identities = 795/795 (100%), Positives = 795/795 (100%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL
Sbjct: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP
Sbjct: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
           AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG
Sbjct: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR
Sbjct: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA
Sbjct: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780
           LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR
Sbjct: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780

Query: 781 DREDQLQTTEESFAK 795
           DREDQLQTTEESFAK
Sbjct: 781 DREDQLQTTEESFAK 795


>gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens]
          Length = 948

 Score = 1548 bits (4008), Expect = 0.0
 Identities = 783/934 (83%), Positives = 837/934 (89%), Gaps = 1/934 (0%)

Query: 15  LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74
           LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK  G L
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+   +DEL + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254
           +L KSLDREE  E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314
             NGTLV+KLNASD DEG N +IVYS  +D+S  +++KF IDPI+G+I  KG +D+EE+K
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374
           SYEI V   DKG   +SGHC++ +++ D NDN P++   SLSLPI E+A LGTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614
           VLDENDNAPALLAPRAG   GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734
           APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTEGA AP
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF- 793
           GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL    D  ++ Q +E  + 
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794

Query: 794 AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 853
            KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP
Sbjct: 795 GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 854

Query: 854 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 913
           PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF
Sbjct: 855 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 914

Query: 914 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 915 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo
           sapiens]
          Length = 950

 Score = 1541 bits (3989), Expect = 0.0
 Identities = 783/947 (82%), Positives = 836/947 (88%), Gaps = 3/947 (0%)

Query: 4   SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63
           SW  G   R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4   SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 64  FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123
           FRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64  FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123

Query: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183
           RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+  
Sbjct: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183

Query: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243
              E +  L L+LRK+LDREE  E  L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F 
Sbjct: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243

Query: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303
           +++YKV +LEN  NGTLVIKLNA+D D+G NGDIVYSF   + P V   F I+P  G+I 
Sbjct: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303

Query: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363
            KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++   SLSLPIRED 
Sbjct: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363

Query: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423
               +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423

Query: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483
           VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483

Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543
           AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543

Query: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603
           PLGSNVTLQVFVLDENDNAPALL P AG  GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603

Query: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663
           NAWLSYELQ    GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663

Query: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
           TVL+SLVESGQAP+ASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723

Query: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP---DSR 780
           SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP    S 
Sbjct: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSA 783

Query: 781 DREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 840
           +   Q +   E   +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS
Sbjct: 784 EGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVS 843

Query: 841 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 900
           SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP
Sbjct: 844 SATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEP 903

Query: 901 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 904 TNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens]
          Length = 936

 Score = 1534 bits (3972), Expect = 0.0
 Identities = 783/940 (83%), Positives = 829/940 (88%), Gaps = 10/940 (1%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G    RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 7   GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN
Sbjct: 67  SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187
           DNPP F   ++ L I ESR  DSRFPLEGASD DIG NA L YRL+PNEYF L+   ++E
Sbjct: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186

Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247
               L L+LRKSLDREE  E  L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY
Sbjct: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246

Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307
            VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN +  +VKSKF I+  TG+I V G 
Sbjct: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306

Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367
           +D+E+  SYEI ++ +DK   PLSGHC+V+V++ D NDN P++   +L LP++EDAPL T
Sbjct: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366

Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VIALISVSD+D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA
Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487
           RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547
           ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS
Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546

Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL
Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606

Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667
           SYELQP  G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV
Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666

Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727
           SLVESGQAPKASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P
Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726

Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787
           TE  C  GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP      D   
Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD--- 783

Query: 788 TTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 847
                   PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE
Sbjct: 784 -------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 836

Query: 848 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 907
           AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK
Sbjct: 837 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 896

Query: 908 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 897 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936


>gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1523 bits (3943), Expect = 0.0
 Identities = 773/937 (82%), Positives = 830/937 (88%), Gaps = 3/937 (0%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R  
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
           P  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF L+   + +  K +G
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+L+KSLDREEAP   L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  NGT VI+LNASD DEG NG I YSF++ ++  V   F ID  TG+I+++G +DFE+ 
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
             Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+REDA  GTVIALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
           SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
               AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
           QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733

Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---PDSRDREDQLQTTE 790
             KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL   P    + +     E
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793

Query: 791 ESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 850
           +  AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE
Sbjct: 794 DHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 853

Query: 851 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 910
           VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF
Sbjct: 854 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 913

Query: 911 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 914 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1520 bits (3936), Expect = 0.0
 Identities = 776/950 (81%), Positives = 834/950 (87%), Gaps = 3/950 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M FS   G  +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           V+V+DINDNPPVF   ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +    DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            FD+ +Y+V LLE   NGTLV  LNASD DEG+NG++V+SF + IS +++ KF +D  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           +I +   +D+EE+KSYEI V+ +DKG  P+S HC+V+V+V D NDN P+L   SL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAPL TVIALI+VSD+D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPR GGT GAVSELVP  VG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  GGARIPFRVGLYTGEISTTR LDE D  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRA VG  GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDS- 779
           LRCS  PTEGA  PGKPTLVCSSA+GSWS SQQRR RVCS EGPPKTDLMAFSP L  S 
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 780 --RDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 837
              +R +Q +   +    PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840

Query: 838 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 897
           TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900

Query: 898 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens]
          Length = 950

 Score = 1516 bits (3925), Expect = 0.0
 Identities = 769/950 (80%), Positives = 829/950 (87%), Gaps = 3/950 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M++ W     S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+D+NDNPPVF    + L ++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +    ++  K + L+LRKSLDRE+AP   L LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            F+++ Y+VR+ EN  NGT VIKLNASD DEG NG I YSF++ +   V   F ID  TG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           +I+++G +DFE+   Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+R
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA  GTVIALISV+D D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRE VSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR   G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP--- 777
           LRCSALPTEG C  GKPTLVCSSAVGSWSYSQQ+  RVCSGEGPPKTDLMAFSP LP   
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDL 780

Query: 778 DSRDREDQLQTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 837
            S D  ++     +   KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP
Sbjct: 781 GSVDVGEEQDLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840

Query: 838 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 897
           TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR
Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900

Query: 898 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950


>gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo
           sapiens]
          Length = 949

 Score = 1509 bits (3907), Expect = 0.0
 Identities = 772/943 (81%), Positives = 831/943 (88%), Gaps = 4/943 (0%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  + RL L LLLL  WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA
Sbjct: 8   GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SK  G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN
Sbjct: 68  SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187
           DNPPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + +
Sbjct: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187

Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247
            +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y
Sbjct: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247

Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307
           KV L+EN    TLV+KLNA+D DEG+NG++ YS  + I PN +  F +D   G++ V G 
Sbjct: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306

Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367
           +D+EE+K Y+I V+  DKG  P++GHC V VE+ D NDN P++   SLSLP+REDA   T
Sbjct: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366

Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA
Sbjct: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547
           ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S
Sbjct: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546

Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALLA +AG  GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL
Sbjct: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606

Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667
           SYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV
Sbjct: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666

Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727
           SLVESGQAPKASSR L GA  P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA P
Sbjct: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726

Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787
           TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP   ++E++ +
Sbjct: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786

Query: 788 TTEESF---AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 844
             E       +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP
Sbjct: 787 RQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 846

Query: 845 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 904
           EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ
Sbjct: 847 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 906

Query: 905 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 907 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949


>gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo
           sapiens]
          Length = 948

 Score = 1494 bits (3869), Expect = 0.0
 Identities = 774/938 (82%), Positives = 823/938 (87%), Gaps = 6/938 (0%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK  G 
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
             T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+     +  K   
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+  TG+I V   IDFE+S
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
            +YEI V+  DKG  P+ GHC V+VE+ D NDN P++   SLSLP++EDA +GTVIALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
            LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552

Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLA  AG  GGAVSELV  SV  GHVVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612

Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
              GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE  
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672

Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
           QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731

Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQLQTT 789
           P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP       D EDQ    
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQSIGG 791

Query: 790 EESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 849
           + S  KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG
Sbjct: 792 DHS-RKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAG 850

Query: 850 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 909
           EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD
Sbjct: 851 EVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSD 910

Query: 910 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 911 FITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948


>gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo
           sapiens]
          Length = 941

 Score = 1489 bits (3854), Expect = 0.0
 Identities = 773/941 (82%), Positives = 820/941 (87%), Gaps = 8/941 (0%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SK  G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186
           DNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K   D
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187

Query: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246
           + +    L+LRK LDRE+ P++ L+L   DGGKPELTG+VQ+ ITVLD NDN PAFD+  
Sbjct: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306
           YKV L ENV N T VI+LNASD DEGLNG+I Y     +  + K  F I+P TG+I + G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366
            +DFEE+ +YEI V  IDKG   ++GH  V+VEV D NDNVP++   SLSLP++EDA +G
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486
           ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG  GGAVSELVP SVG GHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666
           LSYELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726
           VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA 
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786
           PT   CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL  S  RED L
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS--REDCL 784

Query: 787 QTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 846
               E    PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP
Sbjct: 785 NPPSE----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840

Query: 847 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 906
           EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID
Sbjct: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900

Query: 907 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941


>gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo
           sapiens]
          Length = 789

 Score = 1276 bits (3303), Expect = 0.0
 Identities = 654/775 (84%), Positives = 695/775 (89%)

Query: 12  RRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGR 71
           R LLL +++LAAWEAG GQLHYSV EEAKHG FVGRIAQDLGLELAELVPRLFR   K R
Sbjct: 12  RHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFR 71

Query: 72  GGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131
           G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIV+RPLQVFHVDVEV+DINDNPP
Sbjct: 72  GDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPP 131

Query: 132 VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191
           VFPATQ+NL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L+ P  ++ VK 
Sbjct: 132 VFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKP 191

Query: 192 LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251
           LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP FDRT+Y V+L
Sbjct: 192 LGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKL 251

Query: 252 LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311
            ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G I V G++DFE
Sbjct: 252 PENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFE 311

Query: 312 ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371
           ES++++I VE +DKG  PL+GHC V+VEV D NDN P L   SLSLPI EDA  GTVI L
Sbjct: 312 ESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITL 371

Query: 372 ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
           ISV D+D GVNG VTCSLT  VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG
Sbjct: 372 ISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431

Query: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491
           SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVS
Sbjct: 432 SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVS 491

Query: 492 YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551
           YSLVE RVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTL
Sbjct: 492 YSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTL 551

Query: 552 QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611
           QVFVLDENDNAPALLAPR GGTGGAV ELVP SVG GHVVAKVRAVDADSGYNAWLSYEL
Sbjct: 552 QVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYEL 611

Query: 612 QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671
           QP   GA IPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEP+LTATATVLVSLVE
Sbjct: 612 QPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVE 671

Query: 672 SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGA 731
           SGQAPKASSRA +G  GP+  LVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA  +EGA
Sbjct: 672 SGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGA 731

Query: 732 CAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786
           C+  KPTLVCSSAVGSWS+SQQRR RVCSGEGPPKTDLMAFSPSLP      D +
Sbjct: 732 CSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTDNV 786


>gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1272 bits (3291), Expect = 0.0
 Identities = 655/798 (82%), Positives = 705/798 (88%), Gaps = 3/798 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M FSW     ++ LLL LLLLAA E G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+
Sbjct: 61  PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+DINDN PVFP   KNL I+ESR   SRF LEGASDADIG N+LLTY L   EYF+L
Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +   +DE +K LGL+L+K+L+RE+ P+ +L++TA DGGKPELTGT QL ITVLD NDNAP
Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
           AF+RTIYKVRLLEN PNGTLV+ +NA+DLDEG+N DI YSF+ D+S ++ SKFH+DP+ G
Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           QI VKG IDFEESKSYEI VE  DKG  P+S HC V++E+ D NDNVP+L  +SLSLP+ 
Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           ED+PL TVIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDS LDRESVSA
Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATASVSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GG GGAVSELVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDE DAPRHRLLVLVKDHGEP+LT
Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASS+A  GA GP+AALVDVNVYLI+AICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD-- 778
           LRCSA PTEG C PGKPTLVCSSAVGSWSYSQQR+ RVCSGEG PKTDLMAFSPSLP   
Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780

Query: 779 -SRDREDQLQTTEESFAK 795
            SRDRE++     +  AK
Sbjct: 781 ISRDREEKQDVDVDLSAK 798


>gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens]
          Length = 842

 Score = 1259 bits (3258), Expect = 0.0
 Identities = 650/798 (81%), Positives = 700/798 (87%), Gaps = 3/798 (0%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M +S     E + LLL LL+LA W  G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV
Sbjct: 1   MLYSSRGDPEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLF++ SKGRG LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFQLDSKGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+DINDNPPVFPATQKNL IAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYF L
Sbjct: 121 VEVKDINDNPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           + P  ++ VK LGL+LRK LDREE PE+ L+LTATDGGKPELTGTVQLLITVLD NDNAP
Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            FDRT+Y V+L ENV  GTLVI  NASDLDEGLNGDI+YSFS+D+SP++KSKFH+DP++G
Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
            I V G++DFEES++++I VE +DKG  PL+GHC ++VEV D NDN P L  K+LS+P++
Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVK 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA LGTVIALISV D D   NG VTCSLT HVPFKLVST+KNYYSLVLD ALDRESVSA
Sbjct: 361 EDAQLGTVIALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR  GT GAVSE+V  SVG G VV KVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP T  A IPFRVGLYTGEISTTRALDETDAPR RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPK+SSRA VGA GP+  LVDVNVYLIIAICAVSSLLVLTLLLYT 
Sbjct: 661 ATATVLVSLVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTV 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL---P 777
           LRCSA+PTEG CAPGKPTLVCSSAVGSWSYSQQRR RVCSGEG  KTDLMAFSP L    
Sbjct: 721 LRCSAMPTEGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCA 780

Query: 778 DSRDREDQLQTTEESFAK 795
            S +R  +   + +S  K
Sbjct: 781 GSTERTGEPSASSDSTGK 798


>gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo
           sapiens]
          Length = 824

 Score = 1236 bits (3199), Expect = 0.0
 Identities = 630/779 (80%), Positives = 684/779 (87%)

Query: 15  LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74
           LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK  G L
Sbjct: 15  LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74

Query: 75  LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134
           LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP
Sbjct: 75  LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134

Query: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194
            T K +   ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+   +DEL + L L
Sbjct: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194

Query: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254
           +L KSLDREE  E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN
Sbjct: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254

Query: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314
             NGTLV+KLNASD DEG N +IVYS  +D+S  +++KF IDPI+G+I  KG +D+EE+K
Sbjct: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314

Query: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374
           SYEI V   DKG   +SGHC++ +++ D NDN P++   SLSLPI E+A LGTVIALI+V
Sbjct: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374

Query: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434
           SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS
Sbjct: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434

Query: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494
           LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL
Sbjct: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494

Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554
           VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF
Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554

Query: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614
           VLDENDNAPALLAPRAG   GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G
Sbjct: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614

Query: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674
           TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ
Sbjct: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674

Query: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734
           APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS  PTEGA AP
Sbjct: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734

Query: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF 793
           GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL    D  ++ Q +E  +
Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEY 793


>gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1229 bits (3180), Expect = 0.0
 Identities = 628/774 (81%), Positives = 678/774 (87%)

Query: 4   SWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRL 63
           SW  G   R+LLL LL+LAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRL
Sbjct: 4   SWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRL 63

Query: 64  FRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEV 123
           FRVASK  G LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHV+V+V
Sbjct: 64  FRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKV 123

Query: 124 RDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKP 183
           RDINDNPP+FP ++K + IAESRP ++RFPL+GASDADIG N+ LTYRL PN+YF+L+  
Sbjct: 124 RDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQ 183

Query: 184 PDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFD 243
              E +  L L+LRK+LDREE  E  L+LTA+DGGKPELTGTVQLLIT+LD NDNAP F 
Sbjct: 184 NSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFY 243

Query: 244 RTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQII 303
           +++YKV +LEN  NGTLVIKLNA+D D+G NGDIVYSF   + P V   F I+P  G+I 
Sbjct: 244 QSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIR 303

Query: 304 VKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDA 363
            KG +DFEE K YEI VE +DKG +P++GHC ++VEV D NDN P++   SLSLPIRED 
Sbjct: 304 TKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDT 363

Query: 364 PLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYEL 423
               +IALISVSD+D G NG VTC+LT HVPFKLVST+KNYYSLVLDSALDRESVSAYEL
Sbjct: 364 QPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYEL 423

Query: 424 VVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDAD 483
           VVTARDGGSPSLWATASVSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DAD
Sbjct: 424 VVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDAD 483

Query: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVP 543
           AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD+GVP
Sbjct: 484 AQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVP 543

Query: 544 PLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGY 603
           PLGSNVTLQVFVLDENDNAPALL P AG  GG VSEL+P SVG GHVVAKVRAVDADSGY
Sbjct: 544 PLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGY 603

Query: 604 NAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATA 663
           NAWLSYELQ    GARIPFRVGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALTATA
Sbjct: 604 NAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATA 663

Query: 664 TVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723
           TVL+SLVESGQAP+ASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRC
Sbjct: 664 TVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRC 723

Query: 724 SALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777
           SA PTEGACAPGKPTLVCSSA GSWSYSQQRRPRVCSGEGP KTDLMAFSPSLP
Sbjct: 724 SAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLP 777


>gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo
           sapiens]
          Length = 816

 Score = 1228 bits (3178), Expect = 0.0
 Identities = 631/779 (81%), Positives = 678/779 (87%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G    RLLLL LLLA W+AG+GQLHYS+ EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 7   GSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 66

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SKGRG LLEVNLQNGILFVNSRIDREELCRR AECSIHLEVIVDRPLQVFHV+V V+DIN
Sbjct: 67  SKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKDIN 126

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187
           DNPP F   ++ L I ESR  DSRFPLEGASD DIG NA L YRL+PNEYF L+   ++E
Sbjct: 127 DNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTNEE 186

Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247
               L L+LRKSLDREE  E  L++ ATDGGKPELTGTVQLLI VLDANDNAP FD++IY
Sbjct: 187 ETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKSIY 246

Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307
            VRLLEN P+GTLVIKLNASD DEG+N +IVY FSN +  +VKSKF I+  TG+I V G 
Sbjct: 247 NVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVNGE 306

Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367
           +D+E+  SYEI ++ +DK   PLSGHC+V+V++ D NDN P++   +L LP++EDAPL T
Sbjct: 307 LDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPLST 366

Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VIALISVSD+D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRESVS YELVVTA
Sbjct: 367 VIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVVTA 426

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487
           RDGGSPSLWATASVSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 427 RDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQEN 486

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547
           ALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGS
Sbjct: 487 ALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGS 546

Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALL PR GGTGGAVSELVP SVG GHVVAKVRAVD DSGYNAWL
Sbjct: 547 NVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNAWL 606

Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667
           SYELQP  G ARIPFRVGLYTGEISTTR+LDET+APRHRLLVLVKDHGEP LTATATVLV
Sbjct: 607 SYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATVLV 666

Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727
           SLVESGQAPKASSRA  GAVGP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA P
Sbjct: 667 SLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAQP 726

Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786
           TE  C  GKPTL+CSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSLP      D +
Sbjct: 727 TEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTDNV 785


>gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 807

 Score = 1211 bits (3132), Expect = 0.0
 Identities = 624/805 (77%), Positives = 686/805 (85%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M FS   G  +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           V+V+DINDNPPVF   ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +    DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            FD+ +Y+V LLE   NGTLV  LNASD DEG+NG++V+SF + IS +++ KF +D  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           +I +   +D+EE+KSYEI V+ +DKG  P+S HC+V+V+V D NDN P+L   SL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAPL TVIALI+VSD+D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALLAPR GGT GAVSELVP  VG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP  GGARIPFRVGLYTGEISTTR LDE D  R+RLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSRA VG  GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSR 780
           LRCS  PTEGA  PGKPTLVCSSA+GSWS SQQRR RVCS EGPPKTDLMAFSP L  S 
Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780

Query: 781 DREDQLQTTEESFAKPRQPNPDWRY 805
           +  ++ +  E +       +P + +
Sbjct: 781 NTSERNEQPEANLDLSGNVSPTFEF 805


>gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo
           sapiens]
          Length = 803

 Score = 1209 bits (3128), Expect = 0.0
 Identities = 617/763 (80%), Positives = 671/763 (87%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R  
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
           P  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF L+   + +  K +G
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+L+KSLDREEAP   L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  NGT VI+LNASD DEG NG I YSF++ ++  V   F ID  TG+I+++G +DFE+ 
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
             Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+REDA  GTVIALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
           SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLGSNVTLQV
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQV 553

Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLAPR GGTGGAVSELVP S+G G VVAKVRAVDADSGYNAWLSYELQP
Sbjct: 554 FVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQP 613

Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
               AR PFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESG
Sbjct: 614 PASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESG 673

Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
           QAPKASSRA VGA GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 674 QAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACT 733

Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSL 776
             KPTLVCSSAVGSWSYSQQRR RVCSGEGPPK DLMAFSPSL
Sbjct: 734 ADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776


>gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo
           sapiens]
          Length = 814

 Score = 1206 bits (3121), Expect = 0.0
 Identities = 614/777 (79%), Positives = 671/777 (86%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M++ W     S RLLLLLLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELV
Sbjct: 1   MDYHWRGELGSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEV+LQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVD
Sbjct: 61  PRLFRVASKRHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVD 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           VEV+D+NDNPPVF    + L ++ESR  DSRFPLEGASDAD+G N++LTYRLS ++YF L
Sbjct: 121 VEVKDVNDNPPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFML 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +    ++  K + L+LRKSLDRE+AP   L LTATDGGKPELTGTVQLL+TVLD NDNAP
Sbjct: 181 DVNSKNDENKLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            F+++ Y+VR+ EN  NGT VIKLNASD DEG NG I YSF++ +   V   F ID  TG
Sbjct: 241 TFEQSEYEVRIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           +I+++G +DFE+   Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+R
Sbjct: 301 EIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDA  GTVIALISV+D D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRE VSA
Sbjct: 361 EDAQFGTVIALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSA 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATAS+SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDA 540
           DADAQENALVSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEELELLQFQV+ARDA
Sbjct: 481 DADAQENALVSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDA 540

Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDAD 600
           GVPPLGSNVTLQVFVLDENDNAPALL PR GGTGGA S+LVP SVG GHVVAKVRAVDAD
Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDAD 600

Query: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALT 660
           SGYNAWLSYELQP     RIPFRVGLYTGEISTTR LDE D+PRHRLLVLVKDHGEPALT
Sbjct: 601 SGYNAWLSYELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALT 660

Query: 661 ATATVLVSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720
           ATATVLVSLVESGQAPKASSR   G +GP+AALVDVNVYLIIAICAVSSLLVLTLLLYTA
Sbjct: 661 ATATVLVSLVESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720

Query: 721 LRCSALPTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLP 777
           LRCSALPTEG C  GKPTLVCSSAVGSWSYSQQ+  RVCSGEGPPKTDLMAFSP LP
Sbjct: 721 LRCSALPTEGGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLP 777


>gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo
           sapiens]
          Length = 810

 Score = 1202 bits (3111), Expect = 0.0
 Identities = 622/791 (78%), Positives = 680/791 (85%), Gaps = 1/791 (0%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  + RL L LLLL  WE G+GQLHYSVSEEAKHGTFVGRIAQDLGLELAELV RLFRVA
Sbjct: 8   GLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRVA 67

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SK  G LLEVNLQNGILFVNSRIDREELC +SAECSIHLEVIVDRPLQVFHV+VEV+DIN
Sbjct: 68  SKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDIN 127

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDE 187
           DNPPVF   ++ L IAES+  DSRFPLEGASDADI ENALLTYRLS NEYFSL+ P + +
Sbjct: 128 DNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNGK 187

Query: 188 LVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIY 247
            +K L LIL+KSLDRE+ PE+ L+LTATDGGKPELTGTV+LL+ VLD NDN P FD++ Y
Sbjct: 188 QIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSEY 247

Query: 248 KVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGY 307
           KV L+EN    TLV+KLNA+D DEG+NG++ YS  + I PN +  F +D   G++ V G 
Sbjct: 248 KVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVNGT 306

Query: 308 IDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGT 367
           +D+EE+K Y+I V+  DKG  P++GHC V VE+ D NDN P++   SLSLP+REDA   T
Sbjct: 307 LDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPST 366

Query: 368 VIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTA 427
           VIALISVSD+D GVNG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRE+V AYELVVTA
Sbjct: 367 VIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVTA 426

Query: 428 RDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQEN 487
           RDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQEN
Sbjct: 427 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQEN 486

Query: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGS 547
           ALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPL S
Sbjct: 487 ALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLSS 546

Query: 548 NVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWL 607
           NVTLQVFVLDENDNAPALLA +AG  GGAV++LVP SVG GHVVAKVRAVDADSGYNAWL
Sbjct: 547 NVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAWL 606

Query: 608 SYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLV 667
           SYELQP  GG+RIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLV
Sbjct: 607 SYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLV 666

Query: 668 SLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALP 727
           SLVESGQAPKASSR L GA  P+AALVDVNVYLIIAIC VSSLLVLTLLLYTAL  SA P
Sbjct: 667 SLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSATP 726

Query: 728 TEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQ 787
           TEGACAPGKPTLVCS AVGSWSYSQQRR RVCS EGPPKTDLMAFSPSLP   ++E++ +
Sbjct: 727 TEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEGE 786

Query: 788 TTEESFAKPRQ 798
             E     P Q
Sbjct: 787 RQEPGSNHPGQ 797


>gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo
           sapiens]
          Length = 844

 Score = 1184 bits (3064), Expect = 0.0
 Identities = 620/776 (79%), Positives = 668/776 (86%), Gaps = 5/776 (0%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK  G 
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
             T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+     +  K   
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+  TG+I V   IDFE+S
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
            +YEI V+  DKG  P+ GHC V+VE+ D NDN P++   SLSLP++EDA +GTVIALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
            LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQV 553
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARD GVPPLGSN+TLQV
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNLTLQV 552

Query: 554 FVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQP 613
           FVLDENDNAPALLA  AG  GGAVSELV  SV  GHVVAKVRAVDADSGYNAWLSYELQ 
Sbjct: 553 FVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSYELQS 612

Query: 614 GTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESG 673
              GARIPFRVGLYTGEISTTRALDETD+PR RLLVLVKDHGEP+LTATATVLVSLVE  
Sbjct: 613 AAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSLVEGS 672

Query: 674 QAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACA 733
           QAPKASSRA VG V P+ ALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA PTEGAC 
Sbjct: 673 QAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTEGACG 731

Query: 734 PGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPD----SRDREDQ 785
           P KPTLVCSSAVGSWSYSQQRR RVCSGEG PK DLMAFSPSLP       D EDQ
Sbjct: 732 PVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787


>gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo
           sapiens]
          Length = 792

 Score = 1180 bits (3053), Expect = 0.0
 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%)

Query: 8   GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67
           G  S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA
Sbjct: 8   GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67

Query: 68  SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127
           SK  G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN
Sbjct: 68  SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127

Query: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186
           DNPPVF   ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K   D
Sbjct: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187

Query: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246
           + +    L+LRK LDRE+ P++ L+L   DGGKPELTG+VQ+ ITVLD NDN PAFD+  
Sbjct: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246

Query: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306
           YKV L ENV N T VI+LNASD DEGLNG+I Y     +  + K  F I+P TG+I + G
Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306

Query: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366
            +DFEE+ +YEI V  IDKG   ++GH  V+VEV D NDNVP++   SLSLP++EDA +G
Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366

Query: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426
           TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT
Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426

Query: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486
           ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+
Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486

Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546
           NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG
Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546

Query: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606
           SNVTLQVFVLDENDNAPALLA  AG  GGAVSELVP SVG GHVVAKVRAVDADSGYNAW
Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606

Query: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666
           LSYELQP   GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL
Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666

Query: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726
           VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA 
Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726

Query: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781
           PT   CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL  SR+
Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781


>gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor
            [Homo sapiens]
          Length = 1007

 Score =  863 bits (2231), Expect = 0.0
 Identities = 480/988 (48%), Positives = 635/988 (64%), Gaps = 62/988 (6%)

Query: 14   LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
            LLLLLLLL    A + QL YSV EE   G  VG +A+ LGLEL  L P   R+   G   
Sbjct: 28   LLLLLLLLLPGPAAS-QLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPS 86

Query: 74   --LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP 131
               LE++L +G LFVN RIDRE LC +   C + LEV+   P+ V  V+VE+ DINDN P
Sbjct: 87   PRYLELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDNSP 146

Query: 132  VFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKG 191
             FP     L ++ES    +RF +E A D D+G N++ TY LSP+E+F L+  P  E  K 
Sbjct: 147  RFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENSKV 206

Query: 192  LGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRL 251
            L L+LRK LDRE+A    LVLTA DGG P  +GT Q+ + VLD NDN+PAFD++ Y+V+L
Sbjct: 207  LELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRVQL 266

Query: 252  LENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFE 311
             E+ P GTLV+KLNASD DEG NG++ YS S+  S   +  F ID  TG++ V G +D+E
Sbjct: 267  REDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLDYE 326

Query: 312  ESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIAL 371
            E+ SY+I V+  D+G +P++GHC+V+V++ D NDN P++    L  P+ E+A   T++A+
Sbjct: 327  EASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIVAV 386

Query: 372  ISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGG 431
            +SV+D+D G N  V+  L + +PF+L + F N Y+LV+   LDRE V+ Y + VTA DGG
Sbjct: 387  LSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATDGG 445

Query: 432  SPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVS 491
             P L +  ++ VE++D+NDN P+F +  Y+++++ENN PG  + TV A D D +ENA V+
Sbjct: 446  IPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAEVT 505

Query: 492  YSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTL 551
            YSL+ER +    ++SYVS+++ SG +YA+   D+E+       V A+D G PPL S VT 
Sbjct: 506  YSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTVTA 565

Query: 552  QVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611
             V+V+D ND+AP +L P +  +  A  E+VP +   G++V KV A+D+DSG NAWL Y L
Sbjct: 566  NVYVVDMNDHAPHILYPTSTNSSAAF-EMVPRTAPAGYLVTKVIAMDSDSGQNAWLFYHL 624

Query: 612  QPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671
               T    + F+V L+TGEI TTR + +       L V+V+D+GEP+L+A+  + V++V+
Sbjct: 625  AQ-TSDLDL-FKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAVVD 682

Query: 672  SGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEG- 730
                    ++  V +        ++ +YLIIA+  VS + +LT+++ + ++C      G 
Sbjct: 683  RVSKILPDTQRHVKS---PRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAYGT 739

Query: 731  ACAPG-------KPTLVCSSA---------------------VGSWSYSQQRRPRVCSGE 762
            AC  G        P  +   A                      G+ S ++    + C   
Sbjct: 740  ACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACLTA 799

Query: 763  GPPKTDLMAFS-------------PSLPDSRDREDQ----------LQTTEESFAKPRQP 799
            G      M ++              ++ DSR+   Q          L+    S  +PRQP
Sbjct: 800  GSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPRQP 859

Query: 800  NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGV 859
            NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGV
Sbjct: 860  NPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGV 919

Query: 860  NSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEET 919
            NSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEET
Sbjct: 920  NSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEET 979

Query: 920  KKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
            KKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 980  KKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007


>gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  793 bits (2049), Expect = 0.0
 Identities = 405/534 (75%), Positives = 455/534 (85%)

Query: 1   MEFSWGSGQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60
           M FS   G  +R LLL LLLLAAWE G+GQLHYS+ EEAKHGTFVGR+AQDLGLELAELV
Sbjct: 1   MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60

Query: 61  PRLFRVASKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVD 120
           PRLFRVASK    LLEVNLQNGILFVNSRIDREELC+ SAECSIHLE+I DRPLQVFHV+
Sbjct: 61  PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120

Query: 121 VEVRDINDNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSL 180
           V+V+DINDNPPVF   ++ + I ESR L+SRFP+EGA+DADIG NALLTY LSP++YFSL
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180

Query: 181 EKPPDDELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAP 240
           +    DEL K L L LRK LDREE PE+ L+LTATDGGKPEL GTV+LLITVLD NDNAP
Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240

Query: 241 AFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITG 300
            FD+ +Y+V LLE   NGTLV  LNASD DEG+NG++V+SF + IS +++ KF +D  +G
Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300

Query: 301 QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIR 360
           +I +   +D+EE+KSYEI V+ +DKG  P+S HC+V+V+V D NDN P+L   SL LPIR
Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360

Query: 361 EDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSA 420
           EDAPL TVIALI+VSD+D G NG VTCSL  HVPFKLVSTFKNYYSLVLDSALDRES+S 
Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420

Query: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480
           YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA 
Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480

Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  319 bits (817), Expect = 9e-87
 Identities = 152/153 (99%), Positives = 153/153 (100%)

Query: 795 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 854
           +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP
Sbjct: 534 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 593

Query: 855 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 914
           VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG
Sbjct: 594 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 653

Query: 915 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 654 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686



 Score =  145 bits (366), Expect = 2e-34
 Identities = 130/405 (32%), Positives = 185/405 (45%), Gaps = 45/405 (11%)

Query: 289 VKSKFHIDPI-----TGQIIVKGYIDFEE----SKSYEIIVEGIDKGQLPLSGHCRVIVE 339
           V SK H D +      G + V   ID EE    S    I +E I    L +     V V+
Sbjct: 66  VASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVF---HVEVK 122

Query: 340 VEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVS 399
           V+D NDN P    +   + I E   L +   +   +D D+G N L+T +L+    F L  
Sbjct: 123 VKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDV 182

Query: 400 TFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAF 455
              +  S    L L   LDRE      L++TA DGG P L  T  + + V DVNDNAP F
Sbjct: 183 EASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLF 242

Query: 456 AQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL---VERRVGERALSSYVSVHA 512
            Q  Y V + E    G  + T++A DAD   N  V +S    + R + E+       V +
Sbjct: 243 DQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----FKVDS 297

Query: 513 ESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGG 572
            SG++  +  LD+EE +  + QV A D G PP+ ++  + V VLD NDNAP L       
Sbjct: 298 SSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL------- 350

Query: 573 TGGAVSEL---VPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFR-VGLYT 628
              AV+ L   +     +  V+A +   D DSG N  ++  L P      +PF+ V  + 
Sbjct: 351 ---AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFK 402

Query: 629 GEISTT--RALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVE 671
              S     ALD      + L+V  +D G P+L ATA V V + +
Sbjct: 403 NYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVAD 447



 Score =  138 bits (348), Expect = 2e-32
 Identities = 133/467 (28%), Positives = 203/467 (43%), Gaps = 21/467 (4%)

Query: 230 ITVLDANDNAPAFDRTIYKVRLLEN-VPNGTLVIKLNASDLDEGLNGDIVYSFSND--IS 286
           + V D NDN P F      + + E+ + N    I+  A+D D G N  + Y+ S     S
Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIE-GAADADIGANALLTYTLSPSDYFS 179

Query: 287 PNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDN 346
            +V++   +      + ++ Y+D EE+    +++   D G+  L G   +++ V D NDN
Sbjct: 180 LDVEASDELSKSLW-LELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238

Query: 347 VPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYS 406
            P  +     + + E    GT++  ++ SD D GVNG V  S  S +   +   FK   S
Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSS 298

Query: 407 ---LVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVF 463
              + L   LD E   +YE+ V A D GSP +     V V+V DVNDNAP  A     + 
Sbjct: 299 SGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLP 358

Query: 464 VKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPL 523
           ++E+ P    I  ++  D D+  N  V+ SL+   V  + +S++ + ++    +     L
Sbjct: 359 IREDAPLSTVIALITVSDRDSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSAL 413

Query: 524 DHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPW 583
           D E L + +  VTARD G P L +   + V V D NDNAPA   P         +  V  
Sbjct: 414 DRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKE 466

Query: 584 SVGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAP 643
           +   G  +  V A DAD+  NA +SY L     G R          E     AL   D  
Sbjct: 467 NNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHE 526

Query: 644 RHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRALVGAVGPD 690
              LL        P    +A++   +  S    +A      G  GPD
Sbjct: 527 ELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGI-LRAGPGGPD 572


>gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo
           sapiens]
          Length = 686

 Score =  786 bits (2029), Expect = 0.0
 Identities = 398/521 (76%), Positives = 448/521 (85%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAW+ G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK R  
Sbjct: 14  LLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDRED 73

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPP+F
Sbjct: 74  LLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLF 133

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
           P  ++ + I ESR  DS FPLEGASDAD+G N++LTY+LS +EYF L+   + +  K +G
Sbjct: 134 PVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIG 193

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+L+KSLDREEAP   L LTATDGGKPELTGTVQLL+TVLD NDNAP F+++ Y+VR+ E
Sbjct: 194 LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFE 253

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  NGT VI+LNASD DEG NG I YSF++ ++  V   F ID  TG+I+++G +DFE+ 
Sbjct: 254 NADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQE 313

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
             Y+I+++  DKG  P++GHC V+V + D NDNVP++   SLSLP+REDA  GTVIALIS
Sbjct: 314 NLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALIS 373

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           V+D D G NG V CSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP
Sbjct: 374 VNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
           SLWATAS+SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYS
Sbjct: 434 SLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYS 493

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           LVERRVGERALSSY+SVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 494 LVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534



 Score =  319 bits (817), Expect = 9e-87
 Identities = 152/153 (99%), Positives = 153/153 (100%)

Query: 795 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 854
           +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP
Sbjct: 534 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 593

Query: 855 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 914
           VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG
Sbjct: 594 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 653

Query: 915 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 654 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686



 Score =  151 bits (381), Expect = 3e-36
 Identities = 118/395 (29%), Positives = 189/395 (47%), Gaps = 18/395 (4%)

Query: 230 ITVLDANDNAPAFDRTIYKVRLLEN-VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPN 288
           + V D NDN P F     +V + E+ +P+    ++  ASD D G N  + Y  S+     
Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLE-GASDADVGSNSILTYKLSSSEYFG 179

Query: 289 VKSKFHIDPITG-QIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNV 347
           +  K + D      +++K  +D EE+ ++ + +   D G+  L+G  +++V V D NDN 
Sbjct: 180 LDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNA 239

Query: 348 PDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTF---KNY 404
           P  E     + I E+A  GT +  ++ SD+D G NG ++ S  S V   ++  F   +N 
Sbjct: 240 PTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNT 299

Query: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFV 464
             +V+   LD E  + Y++++ A D G P +    +V V + D NDN P  A    ++ V
Sbjct: 300 GEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPV 359

Query: 465 KENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLD 524
           +E+   G  I  +S  D D+  N  V+ SL    V  + +S++ + ++    +     LD
Sbjct: 360 REDAQFGTVIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALD 414

Query: 525 HEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWS 584
            E +   +  VTARD G P L +  +L V V D NDNAPA   P         +  V  +
Sbjct: 415 RESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKEN 467

Query: 585 VGVGHVVAKVRAVDADSGYNAWLSYELQPGTGGAR 619
              G  +  V A DAD+  NA +SY L     G R
Sbjct: 468 NPPGCHIFTVSARDADAQENALVSYSLVERRVGER 502



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 26/83 (31%), Positives = 42/83 (50%), Gaps = 12/83 (14%)

Query: 596 AVDADSGYNAWLSYELQPGTG-GARIPF------RVGLYTGEISTTRALDETDAPRHRLL 648
           A DAD G N+ L+Y+L      G  +        ++GL        ++LD  +AP H L 
Sbjct: 157 ASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGLLL-----KKSLDREEAPAHNLF 211

Query: 649 VLVKDHGEPALTATATVLVSLVE 671
           +   D G+P LT T  +LV++++
Sbjct: 212 LTATDGGKPELTGTVQLLVTVLD 234


>gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo
           sapiens]
          Length = 685

 Score =  785 bits (2028), Expect = 0.0
 Identities = 404/521 (77%), Positives = 447/521 (85%)

Query: 14  LLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGG 73
           LLL LLLLAAWE G+GQLHYSV EEA+HGTFVGRIAQDLGLELAELV RLFRVASK  G 
Sbjct: 13  LLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASKRHGD 72

Query: 74  LLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVF 133
           LLEVNLQNGILFVNSRIDREELC RS ECSIHLEVIVDRPLQVFHVDVEV+DINDNPP F
Sbjct: 73  LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDNPPRF 132

Query: 134 PATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLG 193
             T++ LSI ESR LDSRFPLEGASDAD+GENALLTY+LSPNEYF L+     +  K   
Sbjct: 133 SVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKDKFPV 192

Query: 194 LILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLE 253
           L+LRK LDREE P++ L+LTATDGGKPE TG+V LLI VLDANDNAP FDR +Y+V++ E
Sbjct: 193 LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEVKMYE 252

Query: 254 NVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEES 313
           N  N TLVI+LNASD DEG+N +++YSFS+ + P ++ KF I+  TG+I V   IDFE+S
Sbjct: 253 NQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAIDFEDS 312

Query: 314 KSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALIS 373
            +YEI V+  DKG  P+ GHC V+VE+ D NDN P++   SLSLP++EDA +GTVIALIS
Sbjct: 313 NTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVIALIS 372

Query: 374 VSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSP 433
           VSD D G NG VTCSLT HVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARDGGSP
Sbjct: 373 VSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARDGGSP 432

Query: 434 SLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 493
            LWATASVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS
Sbjct: 433 PLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYS 492

Query: 494 LVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534
           LVERR+GER+LSSYVSVHAESGKVYALQPLDHEELELLQFQ
Sbjct: 493 LVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533



 Score =  319 bits (817), Expect = 9e-87
 Identities = 152/153 (99%), Positives = 153/153 (100%)

Query: 795 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 854
           +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP
Sbjct: 533 QPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPP 592

Query: 855 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 914
           VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG
Sbjct: 593 VGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFG 652

Query: 915 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947
           KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ
Sbjct: 653 KKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 685



 Score =  134 bits (336), Expect = 5e-31
 Identities = 111/392 (28%), Positives = 182/392 (46%), Gaps = 28/392 (7%)

Query: 230 ITVLDANDNAPAFDRTIYKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSND----- 284
           + V D NDN P F  T  K+ + E+    +      ASD D G N  + Y  S +     
Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVL 179

Query: 285 --ISPNVKSKFHIDPITGQIIVKGYIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVED 342
             I+   K KF +      ++++  +D EE+   ++++   D G+   +G   +++ V D
Sbjct: 180 DIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233

Query: 343 NNDNVPDLEFKSLSLPIREDAPLGTVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTF- 401
            NDN P  +     + + E+    T++  ++ SD D G+N  +  S +S VP  +   F 
Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293

Query: 402 --KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPE 459
             +    + ++ A+D E  + YE+ V   D G+P +    +V VE+ D NDN+P      
Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353

Query: 460 YTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYA 519
            ++ VKE+   G  I  +S  D D+  N  V+ SL    V  + +S+Y + ++    +  
Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408

Query: 520 LQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGGTGGAVSE 579
              LD E +   +  VTARD G PPL +  ++ V V D NDNAPA             + 
Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461

Query: 580 LVPWSVGVGHVVAKVRAVDADSGYNAWLSYEL 611
            V  +   G  +  V A DAD+  NA +SY L
Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSL 493


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.133    0.386 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,676,355
Number of Sequences: 37866
Number of extensions: 2036163
Number of successful extensions: 14487
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 211
Number of HSP's successfully gapped in prelim test: 72
Number of HSP's that attempted gapping in prelim test: 6979
Number of HSP's gapped (non-prelim): 1145
length of query: 947
length of database: 18,247,518
effective HSP length: 112
effective length of query: 835
effective length of database: 14,006,526
effective search space: 11695449210
effective search space used: 11695449210
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.