BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] (948 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1862 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1548 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1548 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1543 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1540 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1518 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1509 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1503 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1501 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1493 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1489 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1484 0.0 gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1483 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1479 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1236 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1232 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1226 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1207 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1197 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1195 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1189 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1187 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1179 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1176 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1170 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1167 0.0 gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precurso... 872 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 817 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 783 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 780 0.0 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1862 bits (4824), Expect = 0.0 Identities = 948/948 (100%), Positives = 948/948 (100%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 Query: 781 DSAEEKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 840 DSAEEKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV Sbjct: 781 DSAEEKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTV 840 Query: 841 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 900 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE Sbjct: 841 SSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQE 900 Query: 901 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 PTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1548 bits (4008), Expect = 0.0 Identities = 796/796 (100%), Positives = 796/796 (100%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV Sbjct: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL Sbjct: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP Sbjct: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG Sbjct: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS Sbjct: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA Sbjct: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP Sbjct: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 Query: 781 DSAEEKQLSESEYVGK 796 DSAEEKQLSESEYVGK Sbjct: 781 DSAEEKQLSESEYVGK 796 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1548 bits (4008), Expect = 0.0 Identities = 783/934 (83%), Positives = 837/934 (89%), Gaps = 1/934 (0%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK G L Sbjct: 15 LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+ +DEL + L L Sbjct: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 +L KSLDREE E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN Sbjct: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 NGTLV+KLNASD DEG N +IVYS +D+S +++KF IDPI+G+I KG +D+EE+K Sbjct: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 SYEI V DKG +SGHC++ +++ D NDN P++ SLSLPI E+A LGTVIALI+V Sbjct: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPRAG GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G Sbjct: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTEGA AP Sbjct: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794 GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL D ++ Q +E + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF- 793 Query: 795 GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 854 KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP Sbjct: 794 AKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 853 Query: 855 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 914 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF Sbjct: 854 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 913 Query: 915 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 914 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1543 bits (3995), Expect = 0.0 Identities = 791/950 (83%), Positives = 841/950 (88%), Gaps = 2/950 (0%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M S R G GA LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIH+E+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 V+VKDINDNPP+F + I PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F Q+VY+V LLE TANGTLV LNASDADEG N E+V+S S +S IQ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIR KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPR G GAVSELVP VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQ G ARIPFRVGLYTGEISTTR LDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASSRA VG AG EA LVDVNVYLIIAICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCSVPPTEGA PGKPTLVCSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP LS Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 DSAEEKQLSES--EYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 838 +++E + E+ + G PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 839 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 898 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 899 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1540 bits (3986), Expect = 0.0 Identities = 788/950 (82%), Positives = 841/950 (88%), Gaps = 2/950 (0%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M S R GA LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 VEVKDINDN P+FPM VK + ESR SRF LEGASDADIG N+LL+Y L S+E+F L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D++ NDE +SL LVL K+L+RE+T + LL+ A DGGKPELTGT Q+ I VLDVNDN P Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F +++YKV+LLEN NGTLVV +NA+D DEG N +I YS +D+S+ I +KF +DP++G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 +I KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASS+A GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCS PPTEG PGKPTLVCSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSL P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 DS--AEEKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 838 S EEKQ + + KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 ISRDREEKQDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 839 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 898 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 899 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1518 bits (3931), Expect = 0.0 Identities = 779/950 (82%), Positives = 837/950 (88%), Gaps = 2/950 (0%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M SS + G LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 V+V+DINDNPPIFP + K I ESR ++RFPL+GASDADIGVN+ L+Y+L +++F L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D Q + E SLSLVL K+LDREE E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F QSVYKV +LEN NGTLV+KLNA+D D+G N +IVYS V + FTI+P +G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIRTKGKLD+EE K YEI V A DKG M+GHC + ++++D+NDN PEV+ITSLSLPI Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E+ +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQL ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVL+SLVESGQAP+ASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 DSAE--EKQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 838 SAE ++ +SE + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 GSAEGTGQREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 839 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 898 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 899 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1509 bits (3908), Expect = 0.0 Identities = 768/937 (81%), Positives = 830/937 (88%), Gaps = 4/937 (0%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK DL Sbjct: 15 LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 + + + ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 +L KSLDREE NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 NGT V++LNASD DEG N I YS S V++ + F+ID +GEI +G LD+E+ Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVIALI+V Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPR G GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA Sbjct: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSES 791 KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS P AE + L+E Sbjct: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE- 793 Query: 792 EYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 851 ++ KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE Sbjct: 794 DHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGE 853 Query: 852 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 911 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF Sbjct: 854 VSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDF 913 Query: 912 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 914 ITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1503 bits (3891), Expect = 0.0 Identities = 771/945 (81%), Positives = 831/945 (87%), Gaps = 3/945 (0%) Query: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 RRG G L LLLL WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 INDNPP+F + + + ES+ DSRFPLEGASDADI NALL+Y+LS +E+F LD N Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 + + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 YKV L+EN A TLV+KLNA+D DEG N E+ YSL S + + FT+D +GE+R Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 TARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQ G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 LVSLVESGQAPKASSR GAA EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL S Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785 PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL G + EE Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 KQLSE--SEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 843 + E S + G+PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA Sbjct: 785 GERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 844 Query: 844 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 903 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN Sbjct: 845 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 904 Query: 904 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 905 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1501 bits (3886), Expect = 0.0 Identities = 768/943 (81%), Positives = 819/943 (86%), Gaps = 11/943 (1%) Query: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD- 783 Query: 786 KQLSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 845 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP Sbjct: 784 ----------NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 833 Query: 846 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 905 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ Sbjct: 834 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 893 Query: 906 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 894 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1493 bits (3864), Expect = 0.0 Identities = 758/934 (81%), Positives = 821/934 (87%), Gaps = 11/934 (1%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR K GDL Sbjct: 15 LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T + + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A GTVI LI+V Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPR G GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ Sbjct: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA +G AG E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + Sbjct: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYV 794 KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD---------- 784 Query: 795 GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 854 PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP Sbjct: 785 -NPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSP 843 Query: 855 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 914 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF Sbjct: 844 PVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITF 903 Query: 915 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 904 GKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1489 bits (3855), Expect = 0.0 Identities = 754/941 (80%), Positives = 821/941 (87%), Gaps = 2/941 (0%) Query: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 G+W LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 PP+F + + + ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ + Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + + LVL KSLDRE+ +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 ++ EN NGT V+KLNASD DEG N I YS S V + + F+ID +GEI +G LD Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 +E+ Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PR G GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 VESGQAPKASSR G G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE--EKQ 787 G GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L S + E+Q Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 Query: 788 LSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847 ++ KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 Query: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 Query: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1484 bits (3842), Expect = 0.0 Identities = 757/936 (80%), Positives = 823/936 (87%), Gaps = 2/936 (0%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK GDL Sbjct: 15 LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 D D+ NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS Sbjct: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALL PR GAVSE+V SVGAG VV KVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS PTEG AP Sbjct: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792 GKPTLVCSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP LS S E + + S+ Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794 Query: 793 YVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 852 GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV Sbjct: 795 STGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEV 854 Query: 853 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 912 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI Sbjct: 855 SPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFI 914 Query: 913 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 915 TFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1483 bits (3839), Expect = 0.0 Identities = 765/945 (80%), Positives = 820/945 (86%), Gaps = 13/945 (1%) Query: 7 RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66 RG G+ LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV Sbjct: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126 ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 Query: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186 NDNPP+F + + ES LDS FPLEGASDADIGVN+LL+Y LS +E F L I+ Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 Query: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246 + S LVL K LDRE+T ++NLLL+ DGGKPELTG+VQI I VLDVNDN P F + Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 Query: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306 YKV L EN N T V++LNASD DEG N EI Y + + + + F+I+P +GEIR G Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 Query: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366 +LD+EE +YEIQV A DKG PSM+GH + ++++D+NDN PEV +TSLSLP+ E+A +G Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 Query: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 ARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666 LSYELQ A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 Query: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726 VSLVE+GQAPK SSRA VGA EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 Query: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEK 786 PT APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL---------- 776 Query: 787 QLSESEYV---GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 843 QLS + + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA Sbjct: 777 QLSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 836 Query: 844 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 903 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN Sbjct: 837 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 896 Query: 904 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 897 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1479 bits (3829), Expect = 0.0 Identities = 762/941 (80%), Positives = 816/941 (86%), Gaps = 3/941 (0%) Query: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 G LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 PP F +T + + PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + LVL K LDREE ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 K+ EN N TLV++LNASD+DEG N E++YS S V TI+ KF I+ +GEI+ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 +E++ +YEI V TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA AG+A GAVSELV SV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 VE QAPKASSRA VG A E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP--DSAEEKQ 787 GA P KPTLVCSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSL P D E Q Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 Query: 788 LSESEYVGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847 ++ KPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 788 SIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847 Query: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907 Query: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1236 bits (3199), Expect = 0.0 Identities = 630/779 (80%), Positives = 684/779 (87%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL LLLLAAWE G+GQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK G L Sbjct: 15 LLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKGRGGL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELC RSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+F L+ +DEL + L L Sbjct: 135 ATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLEKPPDDELVKGLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 +L KSLDREE E+ L+L ATDGGKPELTGTVQ+LI VLD NDN P F +++YKV+LLEN Sbjct: 195 ILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTIYKVRLLEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 NGTLV+KLNASD DEG N +IVYS +D+S +++KF IDPI+G+I KG +D+EE+K Sbjct: 255 VPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKGYIDFEESK 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 SYEI V DKG +SGHC++ +++ D NDN P++ SLSLPI E+A LGTVIALI+V Sbjct: 315 SYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 SD+D G NG VTCSLT HVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 SDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQV+ARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPRAG GAVSELVPWSVG GHVVAKVRAVDADSGYNAWLSYELQ G Sbjct: 555 VLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAWLSYELQPG 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 TG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA VGA G +A LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTEGA AP Sbjct: 675 APKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTEGACAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEY 793 GKPTLVCSSAVGSWSYSQQRR RVCSGE PPKTDLMAFSPSL D ++ Q +E + Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQLQTTEESF 793 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1232 bits (3187), Expect = 0.0 Identities = 638/791 (80%), Positives = 687/791 (86%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M S R G GA LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIH+E+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 V+VKDINDNPP+F + I PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F Q+VY+V LLE TANGTLV LNASDADEG N E+V+S S +S IQ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIR KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLAPR G GAVSELVP VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQ G ARIPFRVGLYTGEISTTR LDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASSRA VG AG EA LVDVNVYLIIAICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCSVPPTEGA PGKPTLVCSSA+GSWS SQQRRQRVCS E PPKTDLMAFSP LS Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 781 DSAEEKQLSES 791 +++E + E+ Sbjct: 781 NTSERNEQPEA 791 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1226 bits (3172), Expect = 0.0 Identities = 635/789 (80%), Positives = 686/789 (86%), Gaps = 2/789 (0%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M S R GA LLSLLLLAA EVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MLFSWREDPGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 VEVKDINDN P+FPM VK + ESR SRF LEGASDADIG N+LL+Y L S+E+F L Sbjct: 121 VEVKDINDNAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D++ NDE +SL LVL K+L+RE+T + LL+ A DGGKPELTGT Q+ I VLDVNDN P Sbjct: 181 DVKRNDEEIKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F +++YKV+LLEN NGTLVV +NA+D DEG N +I YS +D+S+ I +KF +DP++G Sbjct: 241 AFERTIYKVRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 +I KG +D+EE+KSYEIQV ATDKG P MS HC + L++VDINDN PE+ I SLSLP+ Sbjct: 301 QISVKGNIDFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVL 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E++ L TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDS LDRESVSA Sbjct: 361 EDSPLSTVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT SVS+EVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQ GTG ARIPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVLVSLVESGQAPKASS+A GA G EA LVDVNVYLI+AICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCS PPTEG PGKPTLVCSSAVGSWSYSQQR+QRVCSGE PKTDLMAFSPSL P Sbjct: 721 LRCSAPPTEGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCP 780 Query: 781 DS--AEEKQ 787 S EEKQ Sbjct: 781 ISRDREEKQ 789 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1207 bits (3122), Expect = 0.0 Identities = 625/784 (79%), Positives = 678/784 (86%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M SS + G LL LL+LAAWE GSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELV Sbjct: 1 MLSSWQGGPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHVE Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 V+V+DINDNPPIFP + K I ESR ++RFPL+GASDADIGVN+ L+Y+L +++F L Sbjct: 121 VKVRDINDNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D Q + E SLSLVL K+LDREE E +LLL A+DGGKPELTGTVQ+LI +LDVNDN P Sbjct: 181 DAQNSLEQMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F QSVYKV +LEN NGTLV+KLNA+D D+G N +IVYS V + FTI+P +G Sbjct: 241 EFYQSVYKVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIRTKGKLD+EE K YEI V A DKG M+GHC + ++++D+NDN PEV+ITSLSLPI Sbjct: 301 EIRTKGKLDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIR 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E+ +IALI+VSDRDSG+NG VTC+LTPHVPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDTQPSAIIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT SVS+ VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQ 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDA 540 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD+ Sbjct: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDS 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALL P AG+A G VSEL+P SVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQL ARIPFRVGLYTGEISTTR LDE D+P HRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALT 660 Query: 661 ATATVLVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTA 720 ATATVL+SLVESGQAP+ASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTA Sbjct: 661 ATATVLLSLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSVPPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 LRCS PPTEGA APGKPTLVCSSA GSWSYSQQRR RVCSGE P KTDLMAFSPSL Sbjct: 721 LRCSAPPTEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCL 780 Query: 781 DSAE 784 SAE Sbjct: 781 GSAE 784 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1197 bits (3098), Expect = 0.0 Identities = 615/779 (78%), Positives = 675/779 (86%), Gaps = 3/779 (0%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK DL Sbjct: 15 LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 + + + ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 +L KSLDREE NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 NGT V++LNASD DEG N I YS S V++ + F+ID +GEI +G LD+E+ Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVIALI+V Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPR G GAVSELVP S+GAG VVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSYELQPP 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 SAR PFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 ASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA VGAAG EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PPTEGA Sbjct: 675 APKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTEGACTA 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP---DSAEEKQLSE 790 KPTLVCSSAVGSWSYSQQRRQRVCSGE PPK DLMAFSPSLS P AE + L+E Sbjct: 735 DKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQDLNE 793 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1195 bits (3092), Expect = 0.0 Identities = 616/779 (79%), Positives = 667/779 (85%) Query: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 RRG LL LLLA W+ GSGQL YS+PEEAKHGTFVGRIAQDLGLEL ELVPRLFR Sbjct: 5 RRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVPRLFR 64 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 VASK GDLLEVNLQNGILFVNSRIDREELC R AECSIH+EVIVDRPLQVFHVEV VKD Sbjct: 65 VASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEVAVKD 124 Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 INDNPP F + + ESR+ DSRFPLEGASD DIG NA L Y+L+ +E+F LD++ N Sbjct: 125 INDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLDVKTN 184 Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 +E + L LVL KSLDREET E LL++ATDGGKPELTGTVQ+LI VLD NDN P F +S Sbjct: 185 EEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPEFDKS 244 Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 +Y V+LLEN +GTLV+KLNASDADEG N EIVY + V +++KF I+ +GEI+ Sbjct: 245 IYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGEIKVN 304 Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 G+LDYE+ SYEI + A DK T +SGHCK+ +KL+D+NDNTPE++IT+L LP+ E+A L Sbjct: 305 GELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKEDAPL 364 Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 TVIALI+VSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRESVS YELVV Sbjct: 365 STVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVYELVV 424 Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 TARDGGSPSLWAT SVS+EVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 425 TARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 ENALVSYSLVERRVGER LSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 GSNVTLQVFVLDENDNAPALL PR G GAVSELVP SVGAGHVVAKVRAVD DSGYNA Sbjct: 545 GSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDSGYNA 604 Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQ GSARIPFRVGLYTGEISTTR+LDE ++PRHRLLVLVKDHGEP LTATATV Sbjct: 605 WLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTATATV 664 Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 LVSLVESGQAPKASSRA GA G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS Sbjct: 665 LVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSA 724 Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 PTE GKPTL+CSSAVGSWSYSQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 725 QPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPTSTD 783 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1189 bits (3077), Expect = 0.0 Identities = 617/785 (78%), Positives = 675/785 (85%), Gaps = 1/785 (0%) Query: 6 RRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFR 65 RRG G L LLLL WEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELV RLFR Sbjct: 6 RRGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFR 65 Query: 66 VASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKD 125 VASK HGDLLEVNLQNGILFVNSRIDREELCG+SAECSIH+EVIVDRPLQVFHV VEVKD Sbjct: 66 VASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKD 125 Query: 126 INDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAN 185 INDNPP+F + + + ES+ DSRFPLEGASDADI NALL+Y+LS +E+F LD N Sbjct: 126 INDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTN 185 Query: 186 DELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQS 245 + + LSL+L KSLDRE+T E+NLLL ATDGGKPELTGTV++L++VLDVNDN+P F +S Sbjct: 186 GKQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKS 245 Query: 246 VYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTK 305 YKV L+EN A TLV+KLNA+D DEG N E+ YSL S + + FT+D +GE+R Sbjct: 246 EYKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMS-IKPNGRHLFTLDQNNGEVRVN 304 Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 G LDYEE K Y+I+V ATDKGTP M+GHC + ++++D NDN+PEV++TSLSLP+ E+A Sbjct: 305 GTLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQP 364 Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVV 425 TVIALI+VSDRDSG NG VTCSLTPHVPFKLVSTFKNYYSLVLDSALDRE+V AYELVV Sbjct: 365 STVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVV 424 Query: 426 TARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ 485 TARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ Sbjct: 425 TARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQ 484 Query: 486 ENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPL 545 ENALVSYSLVERR+G+RALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPL Sbjct: 485 ENALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL 544 Query: 546 GSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNA 605 SNVTLQVFVLDENDNAPALLA +AG+A GAV++LVP SVGAGHVVAKVRAVDADSGYNA Sbjct: 545 SSNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNA 604 Query: 606 WLSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 665 WLSYELQ G +RIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV Sbjct: 605 WLSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATV 664 Query: 666 LVSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSV 725 LVSLVESGQAPKASSR GAA EA LVDVNVYLIIAIC VSSLLVLT+LLYTAL S Sbjct: 665 LVSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSA 724 Query: 726 PPTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE 785 PTEGA APGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL G + EE Sbjct: 725 TPTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEE 784 Query: 786 KQLSE 790 + E Sbjct: 785 GERQE 789 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1187 bits (3070), Expect = 0.0 Identities = 606/770 (78%), Positives = 669/770 (86%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL +++LAAWE G GQL YSVPEEAKHG FVGRIAQDLGLEL ELVPRLFR K GDL Sbjct: 15 LLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELVPRLFRAVCKFRGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIV+RPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVDVEVKDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T + + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 ATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 +++I V A DKG P ++GHC + +++VD+NDN P++++TSLSLPI E+A GTVI LI+V Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIPEDAQPGTVITLISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 DRD G NG VTCSLTP VPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 FDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT SVS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NALVSYSL Sbjct: 435 LWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAGDADAQKNALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VE RVGERALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALLAPR G GAV ELVP SVGAGHVVAKVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPV 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 A IPFRVGLYTGEISTTRALDE D+PRHRLLVLVKDHGEP+LTATATVLVSLVESGQ Sbjct: 615 AAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APKASSRA +G AG E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS P +EGA + Sbjct: 675 APKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPSSEGACSL 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAE 784 KPTLVCSSAVGSWS+SQQRRQRVCSGE PPKTDLMAFSPSL QGP S + Sbjct: 735 VKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGPSSTD 784 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1179 bits (3050), Expect = 0.0 Identities = 602/783 (76%), Positives = 667/783 (85%), Gaps = 3/783 (0%) Query: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 G+W LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFRVASK Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 RH DLLEV+LQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 PP+F + + + ESR+ DSRFPLEGASDAD+G N++L+Y+LSS ++F LD+ + ++ + Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + + LVL KSLDRE+ +L L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 ++ EN NGT V+KLNASD DEG N I YS S V + + F+ID +GEI +G LD Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 +E+ Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALI+V+D DSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GGSPSLWAT S+S+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGER+LSSY+SVH ESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL PR G GA S+LVP SVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ S RIPFRVGLYTGEISTTR LDEADSPRHRLLVLVKDHGEPALTATATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 VESGQAPKASSR G G EA LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQ---GPDSAEEK 786 G GKPTLVCSSAVGSWSYSQQ+ QRVCSGE PPKTDLMAFSP L D EE+ Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 Query: 787 QLS 789 L+ Sbjct: 790 DLN 792 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1176 bits (3043), Expect = 0.0 Identities = 610/770 (79%), Positives = 662/770 (85%) Query: 7 RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66 RG G+ LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV Sbjct: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126 ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 Query: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186 NDNPP+F + + ES LDS FPLEGASDADIGVN+LL+Y LS +E F L I+ Sbjct: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 Query: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246 + S LVL K LDRE+T ++NLLL+ DGGKPELTG+VQI I VLDVNDN P F + Sbjct: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 Query: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306 YKV L EN N T V++LNASD DEG N EI Y + + + + F+I+P +GEIR G Sbjct: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 Query: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366 +LD+EE +YEIQV A DKG PSM+GH + ++++D+NDN PEV +TSLSLP+ E+A +G Sbjct: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 Query: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 ARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 Query: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666 LSYELQ A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 Query: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726 VSLVE+GQAPK SSRA VGA EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P Sbjct: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 Query: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776 PT APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1170 bits (3026), Expect = 0.0 Identities = 605/784 (77%), Positives = 671/784 (85%), Gaps = 2/784 (0%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LLSLL+LA W VGSGQL YSVPEEA+HGTFVGRIAQDLGLEL ELVPRLF++ SK GDL Sbjct: 15 LLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDSKGRGDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEVKDINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 T K + ESR LDSRFPLEGASDADIG NALL+Y+LS +E+FFLD+ +++ + L L Sbjct: 135 ATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQVKPLGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 VL K LDREET E++LLL ATDGGKPELTGTVQ+LI VLD NDN P F +++Y VKL EN Sbjct: 195 VLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYTVKLPEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 + GTLV+ NASD DEG N +I+YS SDVS I++KF +DP+SG I G +D+EE++ Sbjct: 255 VSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHMDFEESR 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 +++I V A DKG P ++GHC + +++VD+NDN P+++I +LS+P+ E+A LGTVIALI+V Sbjct: 315 AHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 D D+ NG VTCSLTPHVPFKLVST+KNYYSLVLD ALDRESVSAYELVVTARDGGSPS Sbjct: 375 IDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT VS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVF 554 VERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLGSNVTLQVF Sbjct: 495 VERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 Query: 555 VLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLG 614 VLDENDNAPALL PR GAVSE+V SVGAG VV KVRAVDADSGYNAWLSYELQ Sbjct: 555 VLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLSYELQPE 614 Query: 615 TGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQ 674 T SA IPFRVGLYTGEISTTRALDE D+PR RLLVLVKDHGEPALTATATVLVSLVESGQ Sbjct: 615 TASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVSLVESGQ 674 Query: 675 APKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAP 734 APK+SSRA VGA G E TLVDVNVYLIIAICAVSSLLVLT+LLYT LRCS PTEG AP Sbjct: 675 APKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPTEGECAP 734 Query: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEE--KQLSESE 792 GKPTLVCSSAVGSWSYSQQRRQRVCSGE KTDLMAFSP LS S E + + S+ Sbjct: 735 GKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGEPSASSD 794 Query: 793 YVGK 796 GK Sbjct: 795 STGK 798 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1167 bits (3018), Expect = 0.0 Identities = 606/771 (78%), Positives = 658/771 (85%), Gaps = 1/771 (0%) Query: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 G LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 PP F +T + + PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + LVL K LDREE ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 K+ EN N TLV++LNASD+DEG N E++YS S V TI+ KF I+ +GEI+ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 +E++ +YEI V TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA AG+A GAVSELV SV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 ELQ ARIPFRVGLYTGEISTTRALDE DSPR RLLVLVKDHGEP+LTATATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 VE QAPKASSRA VG A E LVDVNVYLIIAICAVSSLLVLT+LLYTALRCS PTE Sbjct: 669 VEGSQAPKASSRASVGVA-PEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 GARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGP 780 GA P KPTLVCSSAVGSWSYSQQRRQRVCSGE PK DLMAFSPSL P Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCP 778 >gi|9256600 protocadherin alpha subfamily C, 2 isoform 1 precursor [Homo sapiens] Length = 1007 Score = 872 bits (2252), Expect = 0.0 Identities = 484/990 (48%), Positives = 635/990 (64%), Gaps = 66/990 (6%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV-----ASK 69 LL LLLL + QLRYSVPEE G VG +A+ LGLEL L P R+ S Sbjct: 28 LLLLLLLLLPGPAASQLRYSVPEEQAPGALVGNVARALGLELRRLGPGCLRINHLGAPSP 87 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 R+ LE++L +G LFVN RIDRE LC + C + +EV+ P+ V VEVE+ DINDN Sbjct: 88 RY---LELDLTSGALFVNERIDREALCEQRPRCLLSLEVLAHNPVAVSAVEVEILDINDN 144 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 P FP ++ ES +RF +E A D D+G N++ +Y+LS SE F LD++ E S Sbjct: 145 SPRFPRPNYQLQVSESVAPGARFHIESAQDPDVGANSVQTYELSPSEHFELDLKPLQENS 204 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + L LVL K LDRE+ A +L+L A DGG P +GT QI ++VLD NDN P F QS Y+V Sbjct: 205 KVLELVLRKGLDREQAALHHLVLTAVDGGIPARSGTAQISVRVLDTNDNSPAFDQSTYRV 264 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 +L E++ GTLVVKLNASD DEG N E+ YSL S S + F+ID +GE+R G LD Sbjct: 265 QLREDSPPGTLVVKLNASDPDEGSNGELRYSLSSYTSDRERQLFSIDASTGEVRVIGGLD 324 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 YEEA SY+I V ATD+G M+GHCK+ + +VD+NDN PEV +T L P+ ENA+ T++ Sbjct: 325 YEEASSYQIYVQATDRGPVPMAGHCKVLVDIVDVNDNAPEVVLTDLYSPVPENATPNTIV 384 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 A+++V+D+DSG N V+ L +PF+L + F N Y+LV+ LDRE V+ Y + VTA D Sbjct: 385 AVLSVNDQDSGPNRKVSLGLEATLPFRL-NGFGNSYTLVVSGPLDRERVAVYNITVTATD 443 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GG P L + ++ +E++D+NDN P+F + Y+++++ENN PG + TV A D D +ENA Sbjct: 444 GGIPQLTSLRTLKVEISDINDNPPSFLEDSYSIYIQENNLPGVLLCTVQATDPDEKENAE 503 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNV 549 V+YSL+ER + ++SYVS+++ SG +YA+ D+E+ V A+D G PPL S V Sbjct: 504 VTYSLLEREIQGLPVTSYVSINSASGSLYAVNSFDYEKFREFFVTVEAQDKGSPPLSSTV 563 Query: 550 TLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSY 609 T V+V+D ND+AP +L P T + A E+VP + AG++V KV A+D+DSG NAWL Y Sbjct: 564 TANVYVVDMNDHAPHILYP-TSTNSSAAFEMVPRTAPAGYLVTKVIAMDSDSGQNAWLFY 622 Query: 610 ELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 L S F+V L+TGEI TTR + + L V+V+D+GEP+L+A+ + V++ Sbjct: 623 --HLAQTSDLDLFKVELHTGEIRTTRKMGDESGSTFNLTVVVRDNGEPSLSASVAITVAV 680 Query: 670 VESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTE 729 V+ ++ V S T ++ +YLIIA+ VS + +LT+++ + ++C Sbjct: 681 VDRVSKILPDTQRHV---KSPRTYSEITLYLIIALSTVSFIFLLTIIILSIIKCYRYTAY 737 Query: 730 GA-----------RAPGKPTLVCSSAV------------------GSWSYSQQRRQRVCS 760 G R+P + ++ + G+ S ++ + C Sbjct: 738 GTACCGGFCGVRERSPAELYKQANNNIDARIPHGLKVQPHFIEVRGNGSLTKTYCYKACL 797 Query: 761 GEDPPKTDLMAFSPSLSQGP-DSAEEKQLSESEYV---------------------GKPR 798 M ++ GP S + +++S + +PR Sbjct: 798 TAGSGSDTFMFYNTGAQTGPGPSGAQAAVTDSRNLTGQSGQNAGNLIILKNEAVSQNEPR 857 Query: 799 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 858 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA Sbjct: 858 QPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGA 917 Query: 859 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 918 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE Sbjct: 918 GVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKE 977 Query: 919 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 978 ETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 1007 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 817 bits (2110), Expect = 0.0 Identities = 419/534 (78%), Positives = 460/534 (86%) Query: 1 MASSIRRGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELV 60 M S R G GA LL LLLLAAWEVGSGQL YS+PEEAKHGTFVGR+AQDLGLEL ELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVE 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDREELC SAECSIH+E+I DRPLQVFHVE Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFL 180 V+VKDINDNPP+F + I PESRLL+SRFP+EGA+DADIG NALL+Y LS S++F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 DIQANDELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEP 240 D++A+DELS+SL L L K LDREET E++LLL ATDGGKPEL GTV++LI VLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 TFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISG 300 F Q+VY+V LLE TANGTLV LNASDADEG N E+V+S S +S IQ KF +D SG Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPIS 360 EIR KLDYEE KSYEIQV A DKG+P MS HCK+ +K++D+NDN PE+++TSL LPI Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 ENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSA 420 E+A L TVIALITVSDRDSG NG VTCSL PHVPFKLVSTFKNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534 DADAQENALVSYSLVERRVGERALS+YVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 430 bits (1106), Expect = e-120 Identities = 279/623 (44%), Positives = 345/623 (55%), Gaps = 65/623 (10%) Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395 + +K+ DINDN P + I E+ L + + +D D G N +T +L+P F Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYF 178 Query: 396 KLVSTFKNYYS----LVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451 L + S L L LDRE L++TA DGG P L T + I V DVNDN Sbjct: 179 SLDVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDN 238 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL---VERRVGERALSSYV 508 AP F Q Y V + E G + T++A DAD N V +S + R + E+ Sbjct: 239 APLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEK-----F 293 Query: 509 SVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAP 568 V + SG++ + LD+EE + + QV A D G PP+ ++ + V VLD NDNAP L Sbjct: 294 KVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVT 353 Query: 569 RAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFR-VGLY 627 + + E P S V+A + D DSG N ++ L +PF+ V + Sbjct: 354 ---SLYLPIREDAPLST----VIALITVSDRDSGANGQVTCSLM-----PHVPFKLVSTF 401 Query: 628 TGEISTT--RALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRAWVG 685 S ALD + L+V +D G P+L ATA V V + + A ++ Sbjct: 402 KNYYSLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYT 461 Query: 686 AAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAPGKPTLVCSSAV 745 E +++ + A A + L + Y+ + V G RA V Sbjct: 462 VFVKENNPPGCHIFTVSARDADAQENAL--VSYSLVERRV----GERALSNYVSV----- 510 Query: 746 GSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEKQLSESEYVGKPRQPNPDWR 805 +++ + D + +L+ F P RQPNPDWR Sbjct: 511 ----HAESGKVYALQPLDHEELELLQFQP-----------------------RQPNPDWR 543 Query: 806 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW 865 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW Sbjct: 544 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW 603 Query: 866 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK 925 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK Sbjct: 604 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK 663 Query: 926 KKKGNKTQEKKEKGNSTTDNSDQ 948 KKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 664 KKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 151 bits (381), Expect = 3e-36 Identities = 124/429 (28%), Positives = 200/429 (46%), Gaps = 29/429 (6%) Query: 194 LVLGKSLDREETAE------VNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVY 247 L + +DREE + ++L L+A +P V++ KV D+NDN P F Sbjct: 84 LFVNSRIDREELCQWSAECSIHLELIAD---RPLQVFHVEV--KVKDINDNPPVFRGREQ 138 Query: 248 KVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEI--RTK 305 + + E+ + A+DAD G N+ + Y+L ++ + + D +S + + Sbjct: 139 IIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEAS-DELSKSLWLELR 197 Query: 306 GKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASL 365 LD EE + +TATD G P + G ++ + ++D+NDN P + + E + Sbjct: 198 KYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTAN 257 Query: 366 GTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYS---LVLDSALDRESVSAYE 422 GT++ + SD D G NG V S + + FK S + L LD E +YE Sbjct: 258 GTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSGEIRLIDKLDYEETKSYE 317 Query: 423 LVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDA 482 + V A D GSP + V ++V DVNDNAP A + ++E+ P I ++ D Sbjct: 318 IQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIREDAPLSTVIALITVSDR 377 Query: 483 DAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGV 542 D+ N V+ SL+ V + +S++ + ++ + LD E + + + V+ARD G Sbjct: 378 DSGANGQVTCSLMPH-VPFKLVSTFKNYYS----LVLDSALDRESLSVYELVVTARDGGS 432 Query: 543 PPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSG 602 P L + + V V D NDNAPA P + V + G + V A DAD+ Sbjct: 433 PSLWATARVSVEVADVNDNAPAFAQPE-------YTVFVKENNPPGCHIFTVSARDADAQ 485 Query: 603 YNAWLSYEL 611 NA +SY L Sbjct: 486 ENALVSYSL 494 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 783 bits (2021), Expect = 0.0 Identities = 397/525 (75%), Positives = 445/525 (84%) Query: 10 GAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASK 69 G LLSLLLLAAWEVGSGQL YSV EEA+HGTFVGRIAQDLGLEL ELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDREELCGRS ECSIH+EVIVDRPLQVFHV+VEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELS 189 PP F +T + + PESRLLDSRFPLEGASDAD+G NALL+YKLS +E+F LDI + Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKV 249 + LVL K LDREE ++ LLL ATDGGKPE TG+V +LI VLD NDN P F + VY+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 KLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLD 309 K+ EN N TLV++LNASD+DEG N E++YS S V TI+ KF I+ +GEI+ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 YEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVI 369 +E++ +YEI V TDKG P M GHC + ++L+D NDN+PEV +TSLSLP+ E+A +GTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 ALI+VSD DSG NG VTCSLTPHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENAL 489 GGSP LWAT SVS+EVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQENAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534 VSYSLVERR+GER+LSSYVSVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 414 bits (1063), Expect = e-115 Identities = 273/620 (44%), Positives = 344/620 (55%), Gaps = 59/620 (9%) Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395 + +++ DINDN P S+T L I E+ L + L SD D G N +T L+P+ F Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 396 KLVSTFKN----YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451 L K + LVL LDRE +L++TA DGG P + S+ I V D NDN Sbjct: 178 VLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDN 237 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVH 511 AP F +P Y V + EN + ++A D+D N + YS + + ++ Sbjct: 238 APIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWIN 295 Query: 512 AESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAG 571 +G++ +D E+ + V D G PP+ + T+ V +LDENDN+P ++ Sbjct: 296 ERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT--- 352 Query: 572 TAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFRVGLYTGEI 631 ++S V G V+A + D DSG N ++ L + +PF++ + Sbjct: 353 ----SLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSL-----TPHVPFKL------V 397 Query: 632 STTRALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRAWVGAAGSEA 691 ST + LV D +A LV G +P W A+ S Sbjct: 398 STYK----------NYYSLVLDSALDRERVSAYELVVTARDGGSPPL----WATASVS-V 442 Query: 692 TLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAPGKPTLVCSSAVGSWSYS 751 + DVN A S + V C + A + +A+ S+S Sbjct: 443 EVADVNDN---APAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQ-----ENALVSYSLV 494 Query: 752 QQRRQRVCSGEDPPKTDLMAFSPS---LSQGPDSAEEKQLSESEYVGKPRQPNPDWRYSA 808 ++R GE + + + S + P EE +L + + PRQPNPDWRYSA Sbjct: 495 ERRL-----GERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ----PRQPNPDWRYSA 545 Query: 809 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 868 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK Sbjct: 546 SLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFK 605 Query: 869 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 928 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK Sbjct: 606 YGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKK 665 Query: 929 GNKTQEKKEKGNSTTDNSDQ 948 GNKTQEKKEKGNSTTDNSDQ Sbjct: 666 GNKTQEKKEKGNSTTDNSDQ 685 Score = 147 bits (372), Expect = 4e-35 Identities = 122/425 (28%), Positives = 196/425 (46%), Gaps = 31/425 (7%) Query: 230 IKVLDVNDNEPTFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTI 289 ++V D+NDN P F+ + K+ + E+ + ASDAD G N+ + Y L + Sbjct: 120 VEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPN----- 174 Query: 290 QTKFTIDPISGEIRTKGK-------LDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVD 342 F +D I+ + + K LD EE ++ +TATD G P +G + + ++D Sbjct: 175 -EYFVLDIINKKDKDKFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLD 233 Query: 343 INDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTF- 401 NDN P + + EN T++ + SD D G N + S + VP + F Sbjct: 234 ANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFW 293 Query: 402 --KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPE 459 + + ++ A+D E + YE+ V D G+P + +V +E+ D NDN+P Sbjct: 294 INERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTS 353 Query: 460 YTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYA 519 ++ VKE+ G I +S D D+ N V+ SL V + +S+Y + ++ + Sbjct: 354 LSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTPH-VPFKLVSTYKNYYS----LVL 408 Query: 520 LQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSE 579 LD E V + V+ARD G PPL + ++ V V D NDNAPA A + Sbjct: 409 DSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEYTV 461 Query: 580 LVPWSVGAGHVVAKVRAVDADSGYNAWLSYEL---QLGTGSARIPFRVGLYTGEISTTRA 636 V + G + V A DAD+ NA +SY L +LG S V +G++ + Sbjct: 462 FVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLGERSLSSYVSVHAESGKVYALQP 521 Query: 637 LDEAD 641 LD + Sbjct: 522 LDHEE 526 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 780 bits (2014), Expect = 0.0 Identities = 391/520 (75%), Positives = 447/520 (85%) Query: 15 LLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRVASKRHGDL 74 LL LLLLAAW+VGSGQL YSVPEEAKHGTFVGRIAQDLGLEL ELVPRLFR+ASK DL Sbjct: 15 LLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASKDREDL 74 Query: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDINDNPPIFP 134 LEVNLQNGILFVNSRIDREELCGRSAECSIH+EVIVDRPLQVFHV+VEV+DINDNPP+FP Sbjct: 75 LEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDNPPLFP 134 Query: 135 MTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQANDELSESLSL 194 + + + ESRL DS FPLEGASDAD+G N++L+YKLSSSE+F LD++ N + ++ + L Sbjct: 135 VEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDNKQIGL 194 Query: 195 VLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSVYKVKLLEN 254 +L KSLDREE NL L ATDGGKPELTGTVQ+L+ VLDVNDN PTF QS Y+V++ EN Sbjct: 195 LLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEVRIFEN 254 Query: 255 TANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKGKLDYEEAK 314 NGT V++LNASD DEG N I YS S V++ + F+ID +GEI +G LD+E+ Sbjct: 255 ADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLDFEQEN 314 Query: 315 SYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITV 374 Y+I + ATDKG P M+GHC + ++++D NDN PE+++TSLSLP+ E+A GTVIALI+V Sbjct: 315 LYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVIALISV 374 Query: 375 SDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 +D DSG NG V CSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS Sbjct: 375 NDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 Query: 435 LWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSL 494 LWAT S+S+EVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQENALVSYSL Sbjct: 435 LWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENALVSYSL 494 Query: 495 VERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQ 534 VERRVGERALSSY+SVHAESGKVYALQPLDHEE+ELLQFQ Sbjct: 495 VERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 439 bits (1128), Expect = e-123 Identities = 274/623 (43%), Positives = 350/623 (56%), Gaps = 65/623 (10%) Query: 336 ISLKLVDINDNTPEVSITSLSLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPF 395 + +++ DINDN P + + I E+ +V L SD D G+N +T L+ F Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178 Query: 396 ----KLVSTFKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDN 451 K+ S L+L +LDRE A+ L +TA DGG P L T + + V DVNDN Sbjct: 179 GLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDN 238 Query: 452 APAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVH 511 AP F Q EY V + EN G + ++A D D N +SYS + + + S+ Sbjct: 239 APTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSF--NSLVAAMVIDHFSID 296 Query: 512 AESGKVYALQPLDHEEVELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAG 571 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + Sbjct: 297 RNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEI------ 350 Query: 572 TAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAWLSYELQLGTGSARIPFR-VGLYTGE 630 A ++S V G V+A + D DSG N ++ L + +PF+ V + Sbjct: 351 -ALTSLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSL-----TPHVPFKLVSTFKNY 404 Query: 631 ISTT--RALDEADSPRHRLLVLVKDHGEPALTATATVLVSLVESGQAPKASSRAWVGAAG 688 S ALD + L+V +D G P+L ATA++ V + + A ++ Sbjct: 405 YSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFV 464 Query: 689 SEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVPPTEGARAPGKPTLVCSSAVGSW 748 E +++ + A A + +A+ S+ Sbjct: 465 KENNPPGCHIFTVSARDADAQ--------------------------------ENALVSY 492 Query: 749 SYSQQRRQRVCSGEDPPKTDLMAFSPS---LSQGPDSAEEKQLSESEYVGKPRQPNPDWR 805 S ++R GE + + + S + P EE +L + + PRQPNPDWR Sbjct: 493 SLVERR-----VGERALSSYISVHAESGKVYALQPLDHEELELLQFQ----PRQPNPDWR 543 Query: 806 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW 865 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW Sbjct: 544 YSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSW 603 Query: 866 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK 925 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK Sbjct: 604 TFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKK 663 Query: 926 KKKGNKTQEKKEKGNSTTDNSDQ 948 KKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 664 KKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 173 bits (439), Expect = 6e-43 Identities = 138/472 (29%), Positives = 217/472 (45%), Gaps = 41/472 (8%) Query: 199 SLDREETAEVNL----LLVATDGGKPELTG------------------TVQILIKVLDVN 236 S DRE+ EVNL L V + + EL G + ++V D+N Sbjct: 68 SKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 237 DNEPTFAQSVYKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTID 296 DN P F +V + E+ ++ ASDAD G NS + Y L S + K D Sbjct: 128 DNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSD 187 Query: 297 PISG-EIRTKGKLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSL 355 + K LD EEA ++ + +TATD G P ++G ++ + ++D+NDN P + Sbjct: 188 DNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEY 247 Query: 356 SLPISENASLGTVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTF---KNYYSLVLDSA 412 + I ENA GT + + SDRD G NG ++ S V ++ F +N +V+ Sbjct: 248 EVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGN 307 Query: 413 LDRESVSAYELVVTARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGC 472 LD E + Y++++ A D G P + +V + + D NDN P A ++ V+E+ G Sbjct: 308 LDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGT 367 Query: 473 HIFTVSAWDADAQENALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQ 532 I +S D D+ N V+ SL V + +S++ + ++ + LD E V + Sbjct: 368 VIALISVNDLDSGANGQVNCSLTPH-VPFKLVSTFKNYYS----LVLDSALDRESVSAYE 422 Query: 533 FQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVA 592 V+ARD G P L + +L V V D NDNAPA P + V + G + Sbjct: 423 LVVTARDGGSPSLWATASLSVEVADMNDNAPAFAQPE-------YTVFVKENNPPGCHIF 475 Query: 593 KVRAVDADSGYNAWLSYEL---QLGTGSARIPFRVGLYTGEISTTRALDEAD 641 V A DAD+ NA +SY L ++G + V +G++ + LD + Sbjct: 476 TVSARDADAQENALVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEE 527 Score = 39.7 bits (91), Expect = 0.013 Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 18/196 (9%) Query: 484 AQENALVSYSLVER--RVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 541 AQ+ L LV R R+ + + V+ ++G ++ +D EE+ + S Sbjct: 49 AQDLGLELAELVPRLFRMASKDREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEV 108 Query: 542 VPPLGSNVT-LQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDAD 600 + V + V V D NDN P L P +P SV A DAD Sbjct: 109 IVDRPLQVFHVDVEVRDINDNPP--LFPVEEQRVLIYESRLPDSV-----FPLEGASDAD 161 Query: 601 SGYNAWLSYELQLGTGSARIPFRVGLYTGE-----ISTTRALDEADSPRHRLLVLVKDHG 655 G N+ L+Y+L + S V + + + + ++LD ++P H L + D G Sbjct: 162 VGSNSILTYKL---SSSEYFGLDVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGG 218 Query: 656 EPALTATATVLVSLVE 671 +P LT T +LV++++ Sbjct: 219 KPELTGTVQLLVTVLD 234 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.130 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 37,739,336 Number of Sequences: 37866 Number of extensions: 1874899 Number of successful extensions: 14538 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 216 Number of HSP's successfully gapped in prelim test: 79 Number of HSP's that attempted gapping in prelim test: 6841 Number of HSP's gapped (non-prelim): 1298 length of query: 948 length of database: 18,247,518 effective HSP length: 112 effective length of query: 836 effective length of database: 14,006,526 effective search space: 11709455736 effective search space used: 11709455736 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.