BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] (941 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapi... 1858 0.0 gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sap... 1544 0.0 gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapi... 1507 0.0 gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapi... 1505 0.0 gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] 1498 0.0 gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapi... 1496 0.0 gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] 1489 0.0 gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] 1486 0.0 gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] 1483 0.0 gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] 1474 0.0 gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] 1474 0.0 gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] 1467 0.0 gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] 1463 0.0 gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapi... 1455 0.0 gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sap... 1203 0.0 gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sap... 1194 0.0 gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapi... 1191 0.0 gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sap... 1189 0.0 gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapi... 1182 0.0 gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapi... 1180 0.0 gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapi... 1176 0.0 gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapi... 1169 0.0 gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapi... 1167 0.0 gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapi... 1163 0.0 gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapi... 1156 0.0 gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] 1150 0.0 gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sap... 806 0.0 gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapi... 771 0.0 gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapi... 758 0.0 gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precurs... 605 e-173 >gi|9256578 protocadherin alpha 12 isoform 1 precursor [Homo sapiens] Length = 941 Score = 1858 bits (4814), Expect = 0.0 Identities = 941/941 (100%), Positives = 941/941 (100%) Query: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 Query: 781 EDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 EDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 781 EDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 >gi|14165392 protocadherin alpha 12 isoform 2 precursor [Homo sapiens] Length = 792 Score = 1544 bits (3998), Expect = 0.0 Identities = 789/789 (100%), Positives = 789/789 (100%) Query: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV Sbjct: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD Sbjct: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL Sbjct: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP Sbjct: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG Sbjct: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ Sbjct: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA Sbjct: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR Sbjct: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 Query: 781 EDCLNPPSE 789 EDCLNPPSE Sbjct: 781 EDCLNPPSE 789 >gi|9256574 protocadherin alpha 10 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1507 bits (3901), Expect = 0.0 Identities = 780/941 (82%), Positives = 820/941 (87%), Gaps = 10/941 (1%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP F EQK+ + ES LDS FPLEGASDAD+G N+LLTY LS NE F L I KKDK Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 P LVLRKLLDRE+ P+L LLL DGGKPE TGSV + I VLD NDN P FD+P Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG+N E+ Y ++P + + F IN TGEI++ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE++N YEI V+ DKG P M GH VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL------QLSREDC 783 C P KPTLVCSSAVGSWSYSQQRRQRVCS E PK DLMAFSPSL + ED Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSLPPCPMVDVDGEDQ 787 Query: 784 L---NPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 788 SIGGDHSRKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 847 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 848 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 907 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 908 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|9256576 protocadherin alpha 11 isoform 1 precursor [Homo sapiens] Length = 949 Score = 1505 bits (3896), Expect = 0.0 Identities = 773/944 (81%), Positives = 826/944 (87%), Gaps = 10/944 (1%) Query: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 RG G+ RL L LLLL WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV Sbjct: 7 RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126 Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 NDNPPVF REQK+ ++ES DS FPLEGASDADI N+LLTY LS NE F L T Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186 Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + L+L+K LDRE+TP+LNLLL DGGKPELTG+V++ + VLDVNDN P FDK Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L EN +T V++LNA+D DEG+NGE++Y + I P + + +F+++ + GE+R+ G Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 LD+EEN Y+I+V A DKG P MAGH V VE+LD NDN PEV VTSLSLPV+EDAQ Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+ Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSR GA PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL SA Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS------- 779 PT CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLGLNKEEEG 785 Query: 780 --REDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 837 +E N P +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT Sbjct: 786 ERQEPGSNHPGQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSAT 845 Query: 838 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 897 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS Sbjct: 846 PEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNS 905 Query: 898 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 906 QIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 949 >gi|9256596 protocadherin alpha 8 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1498 bits (3878), Expect = 0.0 Identities = 768/941 (81%), Positives = 821/941 (87%), Gaps = 9/941 (0%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PPVFR ++QK+ VSES DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++ Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 L ELVLRK LDRE P +L L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASDPDEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQPAA IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSP-------SLQLSRED 782 C GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP S+ + E Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCLPPDLGSVDVGEEQ 789 Query: 783 CLNPPS--EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 LN +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 790 DLNVDHGLKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256580 protocadherin alpha 13 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1496 bits (3874), Expect = 0.0 Identities = 766/943 (81%), Positives = 822/943 (87%), Gaps = 9/943 (0%) Query: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 GP ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127 Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L N+ F L + + Sbjct: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187 Query: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247 + LVLRK LDRE+ + +LLL DGGKPELTG+VQ+ IT+LDVNDN P F + Y Sbjct: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247 Query: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307 KV + EN N T VI+LNA+DPD+G NG+I Y + + + F+INP+ GEIR G+ Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307 Query: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367 LDFEE YEI V A+DKG MAGH +LVEVLDVNDN PEV +TSLSLP++ED Q Sbjct: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367 Query: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487 RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487 Query: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667 SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+ Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667 Query: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727 SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727 Query: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQL--------- 778 T CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL Sbjct: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSLPPCLGSAEGTG 787 Query: 779 SREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 838 RE+ EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP Sbjct: 788 QREEDSECLKEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATP 847 Query: 839 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 898 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ Sbjct: 848 EPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQ 907 Query: 899 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 908 IDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256588 protocadherin alpha 4 isoform 1 precursor [Homo sapiens] Length = 947 Score = 1489 bits (3854), Expect = 0.0 Identities = 773/941 (82%), Positives = 820/941 (87%), Gaps = 8/941 (0%) Query: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 SK G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 DNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K D Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186 Query: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + + L+LRK LDRE+ P++ L+L DGGKPELTG+VQ+ ITVLD NDN PAFD+ Sbjct: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L ENV N T VI+LNASD DEGLNG+I Y + + K F I+P TG+I + G Sbjct: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 +DFEE+ +YEI V IDKG ++GH V+VEV D NDNVP++ SLSLP++EDA +G Sbjct: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG GGAVSELVP SVG GHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA Sbjct: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS--REDCL 784 PT CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL S RED L Sbjct: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRDREDQL 786 Query: 785 NPPSE----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 E PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 787 QTTEESFAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 846 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 847 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 906 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 907 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 947 >gi|9256592 protocadherin alpha 6 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1486 bits (3848), Expect = 0.0 Identities = 766/941 (81%), Positives = 816/941 (86%), Gaps = 9/941 (0%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP+F EQ+V + ES DS FPLEGASDAD+G NS+LTY LS +E F L +K D + Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 L+L+K LDRE+ P NL L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQP A A PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE+GQAPK SSRASVGA PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQ-------LSRED 782 C KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL + Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSLSPCPIMMGKAENQ 789 Query: 783 CLNP--PSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 LN ++PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 790 DLNEDHDAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 849 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 850 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 909 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 910 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256584 protocadherin alpha 2 isoform 1 precursor [Homo sapiens] Length = 948 Score = 1483 bits (3839), Expect = 0.0 Identities = 765/945 (80%), Positives = 820/945 (86%), Gaps = 13/945 (1%) Query: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 RG G+ LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV Sbjct: 7 RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126 Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 NDNPP+F + + ES LDS FPLEGASDADIGVN+LL+Y LS +E F L I+ Sbjct: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186 Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + S LVL K LDRE+T ++NLLL+ DGGKPELTG+VQI I VLDVNDN P F + Sbjct: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L EN N T V++LNASD DEG N EI Y + + + + F+I+P +GEIR G Sbjct: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 +LD+EE +YEIQV A DKG PSM+GH + ++++D+NDN PEV +TSLSLP+ E+A +G Sbjct: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQ A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSRA VGA EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P Sbjct: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL---------- 776 PT APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSLSQGPDSAEEK 786 Query: 777 QLSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 836 QLS + + +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA Sbjct: 787 QLSESEYV---GKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSA 843 Query: 837 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 896 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN Sbjct: 844 TPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTN 903 Query: 897 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 904 SQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 948 >gi|9256586 protocadherin alpha 3 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1474 bits (3817), Expect = 0.0 Identities = 757/942 (80%), Positives = 816/942 (86%), Gaps = 9/942 (0%) Query: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS Sbjct: 9 PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128 Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 N PVF + + +SES S F LEGASDADIG NSLLTY+L E F L +K ++ Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188 Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 LVL+K L+RE TPK LL+ IDGGKPELTG+ Q++ITVLDVNDN PAF++ YK Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248 Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 V L EN N T V+ +NA+D DEG+N +I+Y + F ++P G+I + G + Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308 Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 DFEE+ +YEIQV A DKG P M+ H VL+E++D+NDNVPE+++ SLSLPV ED+ + TV Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368 Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 YELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS Sbjct: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668 Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK SS+AS GA PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL---------QLS 779 C PGKPTLVCSSAVGSWSYSQQR+QRVCS E PKTDLMAFSPSL + Sbjct: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSLPPCPISRDREEK 788 Query: 780 REDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 839 ++ ++ ++PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE Sbjct: 789 QDVDVDLSAKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 Query: 840 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 899 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI Sbjct: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 Query: 900 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256594 protocadherin alpha 7 isoform 1 precursor [Homo sapiens] Length = 937 Score = 1474 bits (3817), Expect = 0.0 Identities = 759/941 (80%), Positives = 807/941 (85%), Gaps = 6/941 (0%) Query: 3 IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 ++ P G PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV Sbjct: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD Sbjct: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 VEVKDINDNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 + T + LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 FD+ Y V L ENV T VI NASD DEGLNG+I Y + K F ++P +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 I + G +DFEE+ A++I V A+DKG P +AGH VLVEV+DVNDN P++ +TSLSLP+ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GGAV ELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRAS+G PE LVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 LRCSAP + C+ KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSLPQGP 780 Query: 781 EDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 840 N PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP Sbjct: 781 SSTDN----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEP 836 Query: 841 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 900 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID Sbjct: 837 EAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQID 896 Query: 901 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 897 KSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 937 >gi|9256582 protocadherin alpha 1 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1467 bits (3799), Expect = 0.0 Identities = 757/950 (79%), Positives = 816/950 (85%), Gaps = 9/950 (0%) Query: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 MV G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 V+VKDINDNPPVFR REQ + + ES L+S FP+EGA+DADIG N+LLTY LS ++ F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 ++ + S L LRK LDRE+TP+L+LLL DGGKPEL G+V++ ITVLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 FD+ Y+V L E N T V LNASD DEG+NGE+ + + + F ++ +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 EIR+ +LD+EE +YEIQV A+DKG P M+ H VLV+VLDVNDN PE+ VTSL LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GAVSELVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAA GA IPF VGLYTGEISTTR+LDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRASVG PEAALVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLS- 779 LRCS PPT PGKPTLVCSSA+GSWS SQQRRQRVCS+E PPKTDLMAFSP L S Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPSL 780 Query: 780 --------REDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 831 E L+ PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP Sbjct: 781 NTSERNEQPEANLDLSGNPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWP 840 Query: 832 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 891 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR Sbjct: 841 TVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIR 900 Query: 892 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 901 QEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|9256590 protocadherin alpha 5 isoform 1 precursor [Homo sapiens] Length = 936 Score = 1463 bits (3787), Expect = 0.0 Identities = 751/940 (79%), Positives = 810/940 (86%), Gaps = 4/940 (0%) Query: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSLPQGPT 780 Query: 782 DCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 841 N PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE Sbjct: 781 STDN----PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPE 836 Query: 842 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 901 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK Sbjct: 837 AGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDK 896 Query: 902 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 897 SDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 936 >gi|14165425 protocadherin alpha 9 isoform 1 precursor [Homo sapiens] Length = 950 Score = 1455 bits (3766), Expect = 0.0 Identities = 753/942 (79%), Positives = 804/942 (85%), Gaps = 9/942 (0%) Query: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 P Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S Sbjct: 9 PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND Sbjct: 69 KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 NPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T + Sbjct: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P FD+ Y Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 V L ENV T VI NASD DEGLNG+I Y + K F ++P +G I + G + Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 DFEE+ A++I V A+DKG P +AGH +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368 Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR Sbjct: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608 Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 YELQP A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS Sbjct: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK+SSRASVGA PE LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT Sbjct: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728 Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQ--LSREDCLNP 786 CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E KTDLMAFSP L + Sbjct: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGLSPCAGSTERTGE 788 Query: 787 PS-------EPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 839 PS +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE Sbjct: 789 PSASSDSTGKPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPE 848 Query: 840 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 899 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI Sbjct: 849 PEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQI 908 Query: 900 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 909 DKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 950 >gi|14165381 protocadherin alpha 10 isoform 2 precursor [Homo sapiens] Length = 844 Score = 1203 bits (3113), Expect = 0.0 Identities = 626/767 (81%), Positives = 663/767 (86%), Gaps = 1/767 (0%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP F EQK+ + ES LDS FPLEGASDAD+G N+LLTY LS NE F L I KKDK Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 P LVLRKLLDRE+ P+L LLL DGGKPE TGSV + I VLD NDN P FD+P Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG+N E+ Y ++P + + F IN TGEI++ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE++N YEI V+ DKG P M GH VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD GVPPLGSN+ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDGGVPPLGSNL 548 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA+PAGSAGGAVSELV RSV AGHVVAKVRAVDADSGYNAWLSY Sbjct: 549 TLQVFVLDENDNAPALLASPAGSAGGAVSELVLRSVVAGHVVAKVRAVDADSGYNAWLSY 608 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQ AAVGA IPF VGLYTGEISTTR LDE D+PR RLLVLVKDHGEP+LT+TATVLVSL Sbjct: 609 ELQSAAVGARIPFRVGLYTGEISTTRALDETDSPRQRLLVLVKDHGEPSLTATATVLVSL 668 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE QAPK SSRASVG V PE ALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 669 VEGSQAPKASSRASVG-VAPEVALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAAPTE 727 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 C P KPTLVCSSAVGSWSYSQQRRQRVCS E PK DLMAFSPSL Sbjct: 728 GACGPVKPTLVCSSAVGSWSYSQQRRQRVCSGEGLPKADLMAFSPSL 774 >gi|14165387 protocadherin alpha 11 isoform 2 precursor [Homo sapiens] Length = 810 Score = 1194 bits (3090), Expect = 0.0 Identities = 622/789 (78%), Positives = 674/789 (85%), Gaps = 5/789 (0%) Query: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 RG G+ RL L LLLL WEVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELV RLFRV Sbjct: 7 RGLGTPRLQLWLLLLEFWEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVQRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 ASK HGDLLEVNLQNGILFVNSRIDRE+LCG+SAECSIHLEVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKTHGDLLEVNLQNGILFVNSRIDREELCGQSAECSIHLEVIVDRPLQVFHVNVEVKDI 126 Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 NDNPPVF REQK+ ++ES DS FPLEGASDADI N+LLTY LS NE F L T Sbjct: 127 NDNPPVFSLREQKLLIAESKQSDSRFPLEGASDADIEENALLTYRLSKNEYFSLDSPTNG 186 Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + L+L+K LDRE+TP+LNLLL DGGKPELTG+V++ + VLDVNDN P FDK Sbjct: 187 KQIKRLSLILKKSLDREKTPELNLLLTATDGGKPELTGTVRLLVQVLDVNDNDPEFDKSE 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L EN +T V++LNA+D DEG+NGE++Y + I P + + +F+++ + GE+R+ G Sbjct: 247 YKVSLMENAAKETLVLKLNATDRDEGVNGEVTYSLMSIKP-NGRHLFTLDQNNGEVRVNG 305 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 LD+EEN Y+I+V A DKG P MAGH V VE+LD NDN PEV VTSLSLPV+EDAQ Sbjct: 306 TLDYEENKFYKIEVQATDKGTPPMAGHCTVWVEILDTNDNSPEVAVTSLSLPVREDAQPS 365 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRE+V AYELVVT Sbjct: 366 TVIALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRENVWAYELVVT 425 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+ Sbjct: 426 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQE 485 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERR+G+ ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPL Sbjct: 486 NALVSYSLVERRLGDRALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLS 545 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLAT AGSAGGAV++LVPRSVGAGHVVAKVRAVDADSGYNAW Sbjct: 546 SNVTLQVFVLDENDNAPALLATQAGSAGGAVNKLVPRSVGAGHVVAKVRAVDADSGYNAW 605 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQPAA G+ IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 606 LSYELQPAAGGSRIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 665 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSR GA PEAALVD+NVYLIIAIC VSSLLVLTLLLYTAL SA Sbjct: 666 VSLVESGQAPKASSRTLAGAASPEAALVDVNVYLIIAICVVSSLLVLTLLLYTALWWSAT 725 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSREDCLNP 786 PT CAPGKPTLVCS AVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL L LN Sbjct: 726 PTEGACAPGKPTLVCSRAVGSWSYSQQRRQRVCSEEGPPKTDLMAFSPSLPLG----LNK 781 Query: 787 PSEPRQPNP 795 E + P Sbjct: 782 EEEGERQEP 790 >gi|14165422 protocadherin alpha 8 isoform 2 precursor [Homo sapiens] Length = 814 Score = 1191 bits (3081), Expect = 0.0 Identities = 613/767 (79%), Positives = 663/767 (86%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 GS RLLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVASK Sbjct: 10 GSWRLLLLLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 RH DLLEV+LQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKD+NDN Sbjct: 70 RHRDLLEVSLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDVNDN 129 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PPVFR ++QK+ VSES DS FPLEGASDAD+G NS+LTY LS ++ F L + +K D++ Sbjct: 130 PPVFRVKDQKLFVSESRMPDSRFPLEGASDADVGANSVLTYRLSSHDYFMLDVNSKNDEN 189 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 L ELVLRK LDRE P +L L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 KLVELVLRKSLDREDAPAHHLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASDPDEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 RIFENADNGTTVIKLNASDPDEGANGAISYSFNSLVETMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRERVSAYELVVTARD 429 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSPSLWATA +SVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE +LSSY+SVH ESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERSLSSYISVHTESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALL G GGA S+LVPRSVGAGHVVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLEPRVGGTGGAASKLVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQPAA IPF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPAASSPRIPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE+GQAPK SSR S G + PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA PT Sbjct: 670 VESGQAPKASSRQSAGVLGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSALPTE 729 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 C GKPTLVCSSAVGSWSYSQQ+ QRVCS E PPKTDLMAFSP L Sbjct: 730 GGCRAGKPTLVCSSAVGSWSYSQQQPQRVCSGEGPPKTDLMAFSPCL 776 >gi|14165397 protocadherin alpha 13 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1189 bits (3076), Expect = 0.0 Identities = 611/769 (79%), Positives = 666/769 (86%) Query: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 GP ++LLL LL+LAAWE GSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GPRPRQLLLWLLILAAWETGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 SKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+V+V+DIN Sbjct: 68 SKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVKVRDIN 127 Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 DNPP+F E ++++ ++ES P ++ FPL+GASDADIGVNS LTY L N+ F L + + Sbjct: 128 DNPPIFPESKKRIIIAESRPPETRFPLDGASDADIGVNSALTYRLDPNDYFTLDAQNSLE 187 Query: 188 KSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSY 247 + LVLRK LDRE+ + +LLL DGGKPELTG+VQ+ IT+LDVNDN P F + Y Sbjct: 188 QMSSLSLVLRKTLDREEIQEHSLLLTASDGGKPELTGTVQLLITILDVNDNAPEFYQSVY 247 Query: 248 KVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGE 307 KV + EN N T VI+LNA+DPD+G NG+I Y + + + F+INP+ GEIR G+ Sbjct: 248 KVTVLENAFNGTLVIKLNATDPDDGTNGDIVYSFRRPVWPAVVYAFTINPNNGEIRTKGK 307 Query: 308 LDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGT 367 LDFEE YEI V A+DKG MAGH +LVEVLDVNDN PEV +TSLSLP++ED Q Sbjct: 308 LDFEEKKLYEISVEAVDKGNIPMAGHCTLLVEVLDVNDNAPEVTITSLSLPIREDTQPSA 367 Query: 368 VIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 +IALISVSDRDSG+NGQV C+LTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA Sbjct: 368 IIALISVSDRDSGSNGQVTCTLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTA 427 Query: 428 RDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKN 487 RDGGSPSLWATA VSV VADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+N Sbjct: 428 RDGGSPSLWATASVSVGVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAQDADAQEN 487 Query: 488 ALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGS 547 ALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARD+GVPPLGS Sbjct: 488 ALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDSGVPPLGS 547 Query: 548 NVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWL 607 NVTLQVFVLDENDNAPALL AGSAGG VSEL+PRSVGAGHVVAKVRAVDADSGYNAWL Sbjct: 548 NVTLQVFVLDENDNAPALLTPGAGSAGGTVSELMPRSVGAGHVVAKVRAVDADSGYNAWL 607 Query: 608 SYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLV 667 SYELQ AAVGA IPF VGLYTGEISTTR LDE DAP HRLLVLVKDHGEPALT+TATVL+ Sbjct: 608 SYELQLAAVGARIPFRVGLYTGEISTTRPLDEVDAPHHRLLVLVKDHGEPALTATATVLL 667 Query: 668 SLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727 SLVE+GQAP+ SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPP Sbjct: 668 SLVESGQAPQASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPP 727 Query: 728 TVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 T CAPGKPTLVCSSA GSWSYSQQRR RVCS E P KTDLMAFSPSL Sbjct: 728 TEGACAPGKPTLVCSSAAGSWSYSQQRRPRVCSGEGPHKTDLMAFSPSL 776 >gi|14165390 protocadherin alpha 6 isoform 2 precursor [Homo sapiens] Length = 803 Score = 1182 bits (3057), Expect = 0.0 Identities = 612/767 (79%), Positives = 659/767 (85%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP+F EQ+V + ES DS FPLEGASDAD+G NS+LTY LS +E F L +K D + Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 L+L+K LDRE+ P NL L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNV 549 Query: 550 TLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSY 609 TLQVFVLDENDNAPALLA G GGAVSELVPRS+GAG VVAKVRAVDADSGYNAWLSY Sbjct: 550 TLQVFVLDENDNAPALLAPRVGGTGGAVSELVPRSLGAGQVVAKVRAVDADSGYNAWLSY 609 Query: 610 ELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSL 669 ELQP A A PF VGLYTGEISTTR+LDEAD+PRHRLLVLVKDHGEPALT+TATVLVSL Sbjct: 610 ELQPPASSARFPFRVGLYTGEISTTRVLDEADSPRHRLLVLVKDHGEPALTATATVLVSL 669 Query: 670 VENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPTV 729 VE+GQAPK SSRASVGA PEAALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 670 VESGQAPKASSRASVGAAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAPPTE 729 Query: 730 SRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 C KPTLVCSSAVGSWSYSQQRRQRVCS E PPK DLMAFSPSL Sbjct: 730 GACTADKPTLVCSSAVGSWSYSQQRRQRVCSGEGPPKMDLMAFSPSL 776 >gi|14165413 protocadherin alpha 4 isoform 2 precursor [Homo sapiens] Length = 798 Score = 1180 bits (3053), Expect = 0.0 Identities = 617/775 (79%), Positives = 665/775 (85%), Gaps = 2/775 (0%) Query: 8 GPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 G S+RLLL LLLLAAWE G+GQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVA Sbjct: 8 GQESRRLLLLLLLLAAWEAGNGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVA 67 Query: 68 SKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIN 127 SK G LLEVNLQNGILFVNSRIDRE+LC RSAECSIHLEVIVDRPLQVFHVDVEV+DIN Sbjct: 68 SKGRGGLLEVNLQNGILFVNSRIDREELCRRSAECSIHLEVIVDRPLQVFHVDVEVRDIN 127 Query: 128 DNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKD 187 DNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L+ K D Sbjct: 128 DNPPVFPATQKNLSIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFSLE-KPPDD 186 Query: 188 KSILP-ELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + + L+LRK LDRE+ P++ L+L DGGKPELTG+VQ+ ITVLD NDN PAFD+ Sbjct: 187 ELVKGLGLILRKSLDREEAPEIFLVLTATDGGKPELTGTVQLLITVLDANDNAPAFDRTI 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L ENV N T VI+LNASD DEGLNG+I Y + + K F I+P TG+I + G Sbjct: 247 YKVRLLENVPNGTLVIKLNASDLDEGLNGDIVYSFSNDISPNVKSKFHIDPITGQIIVKG 306 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 +DFEE+ +YEI V IDKG ++GH V+VEV D NDNVP++ SLSLP++EDA +G Sbjct: 307 YIDFEESKSYEIIVEGIDKGQLPLSGHCRVIVEVEDNNDNVPDLEFKSLSLPIREDAPLG 366 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALISVSD+D G NG V CSLT HVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALISVSDKDMGVNGLVTCSLTSHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQV+ARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVTARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG GGAVSELVP SVG GHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGGTGGAVSELVPWSVGVGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQPGTGGARIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPALTATATVL 666 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSRA VGAV P+AALVD+NVYLIIAICAVSSLLVLTLLLYTALRCSA Sbjct: 667 VSLVESGQAPKASSRALVGAVGPDAALVDVNVYLIIAICAVSSLLVLTLLLYTALRCSAL 726 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSRE 781 PT CAPGKPTLVCSSAVGSWSYSQQRR RVCS E PPKTDLMAFSPSL SR+ Sbjct: 727 PTEGACAPGKPTLVCSSAVGSWSYSQQRRPRVCSGEGPPKTDLMAFSPSLPDSRD 781 >gi|14165405 protocadherin alpha 2 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1176 bits (3043), Expect = 0.0 Identities = 610/770 (79%), Positives = 662/770 (85%) Query: 7 RGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRV 66 RG G+ LLSLLLLAAWEVGSGQL YSV EEAKHGTFVGRIAQDLGLEL ELVPRLFRV Sbjct: 7 RGRGAWTRLLSLLLLAAWEVGSGQLRYSVPEEAKHGTFVGRIAQDLGLELEELVPRLFRV 66 Query: 67 ASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDI 126 ASKRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIH+EVIVDRPLQVFHV+VEVKDI Sbjct: 67 ASKRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHVEVIVDRPLQVFHVEVEVKDI 126 Query: 127 NDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKK 186 NDNPP+F + + ES LDS FPLEGASDADIGVN+LL+Y LS +E F L I+ Sbjct: 127 NDNPPIFPMTVKTIRFPESRLLDSRFPLEGASDADIGVNALLSYKLSSSEFFFLDIQAND 186 Query: 187 DKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPS 246 + S LVL K LDRE+T ++NLLL+ DGGKPELTG+VQI I VLDVNDN P F + Sbjct: 187 ELSESLSLVLGKSLDREETAEVNLLLVATDGGKPELTGTVQILIKVLDVNDNEPTFAQSV 246 Query: 247 YKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYG 306 YKV L EN N T V++LNASD DEG N EI Y + + + + F+I+P +GEIR G Sbjct: 247 YKVKLLENTANGTLVVKLNASDADEGPNSEIVYSLGSDVSSTIQTKFTIDPISGEIRTKG 306 Query: 307 ELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVG 366 +LD+EE +YEIQV A DKG PSM+GH + ++++D+NDN PEV +TSLSLP+ E+A +G Sbjct: 307 KLDYEEAKSYEIQVTATDKGTPSMSGHCKISLKLVDINDNTPEVSITSLSLPISENASLG 366 Query: 367 TVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVT 426 TVIALI+VSDRDSG NG V CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVT Sbjct: 367 TVIALITVSDRDSGTNGHVTCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVT 426 Query: 427 ARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQK 486 ARDGGSPSLWAT VS+EVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQ+ Sbjct: 427 ARDGGSPSLWATTSVSIEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQE 486 Query: 487 NALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLG 546 NALVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAGVPPLG Sbjct: 487 NALVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAGVPPLG 546 Query: 547 SNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAW 606 SNVTLQVFVLDENDNAPALLA AG+A GAVSELVP SVGAGHVVAKVRAVDADSGYNAW Sbjct: 547 SNVTLQVFVLDENDNAPALLAPRAGTAAGAVSELVPWSVGAGHVVAKVRAVDADSGYNAW 606 Query: 607 LSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVL 666 LSYELQ A IPF VGLYTGEISTTR LDEAD+PRHRLLVLVKDHGEPALT+TATVL Sbjct: 607 LSYELQLGTGSARIPFRVGLYTGEISTTRALDEADSPRHRLLVLVKDHGEPALTATATVL 666 Query: 667 VSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAP 726 VSLVE+GQAPK SSRA VGA EA LVD+NVYLIIAICAVSSLLVLT+LLYTALRCS P Sbjct: 667 VSLVESGQAPKASSRAWVGAAGSEATLVDVNVYLIIAICAVSSLLVLTVLLYTALRCSVP 726 Query: 727 PTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 PT APGKPTLVCSSAVGSWSYSQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 727 PTEGARAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEDPPKTDLMAFSPSL 776 >gi|14165410 protocadherin alpha 3 isoform 2 precursor [Homo sapiens] Length = 824 Score = 1169 bits (3025), Expect = 0.0 Identities = 605/768 (78%), Positives = 657/768 (85%) Query: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 PG+Q LLLSLLLLAA EVGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFRVAS Sbjct: 9 PGAQCLLLSLLLLAASEVGSGQLHYSVSEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 KRHGDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHV+VEVKDIND Sbjct: 69 KRHGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVEVEVKDIND 128 Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 N PVF + + +SES S F LEGASDADIG NSLLTY+L E F L +K ++ Sbjct: 129 NAPVFPMAVKNLFISESRQPGSRFSLEGASDADIGTNSLLTYSLDSTEYFTLDVKRNDEE 188 Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 LVL+K L+RE TPK LL+ IDGGKPELTG+ Q++ITVLDVNDN PAF++ YK Sbjct: 189 IKSLGLVLKKNLNREDTPKHYLLITAIDGGKPELTGTTQLKITVLDVNDNAPAFERTIYK 248 Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 V L EN N T V+ +NA+D DEG+N +I+Y + F ++P G+I + G + Sbjct: 249 VRLLENAPNGTLVVTVNATDLDEGVNKDIAYSFNTDMSADILSKFHLDPVNGQISVKGNI 308 Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 DFEE+ +YEIQV A DKG P M+ H VL+E++D+NDNVPE+++ SLSLPV ED+ + TV Sbjct: 309 DFEESKSYEIQVEATDKGNPPMSDHCTVLLEIVDINDNVPELVIQSLSLPVLEDSPLSTV 368 Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISVSDRDSG NGQV CSLTPHVPFKLVST+KNYYSLVLDS LDRESVSAYELVVTAR Sbjct: 369 IALISVSDRDSGVNGQVTCSLTPHVPFKLVSTFKNYYSLVLDSPLDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 DGGSPSLWATA VSVEVADVNDNAPAF+Q EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATASVSVEVADVNDNAPAFSQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERRVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLMPRVGGIGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 YELQP GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT+TATVLVS Sbjct: 609 YELQPGTGGARIPFRVGLYTGEISTTRALDEVDAPRHRLLVLVKDHGEPSLTATATVLVS 668 Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK SS+AS GA PEAALVD+NVYLI+AICAVSSLLVLTLLLYTALRCSAPPT Sbjct: 669 LVESGQAPKASSQASAGATGPEAALVDVNVYLIVAICAVSSLLVLTLLLYTALRCSAPPT 728 Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 C PGKPTLVCSSAVGSWSYSQQR+QRVCS E PKTDLMAFSPSL Sbjct: 729 EGDCGPGKPTLVCSSAVGSWSYSQQRQQRVCSGEGLPKTDLMAFSPSL 776 >gi|14165419 protocadherin alpha 7 isoform 2 precursor [Homo sapiens] Length = 789 Score = 1167 bits (3020), Expect = 0.0 Identities = 606/776 (78%), Positives = 654/776 (84%), Gaps = 2/776 (0%) Query: 3 IIGPRG--PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 ++ P G PG + LLL +++LAAWE G GQLHYSV EEAKHG FVGRIAQDLGLELAELV Sbjct: 1 MVCPNGYDPGGRHLLLFIIILAAWEAGRGQLHYSVPEEAKHGNFVGRIAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFR K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIV+RPLQVFHVD Sbjct: 61 PRLFRAVCKFRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVERPLQVFHVD 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 VEVKDINDNPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L Sbjct: 121 VEVKDINDNPPVFPATQRNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 + T + LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P Sbjct: 181 DVPTSNQQVKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 FD+ Y V L ENV T VI NASD DEGLNG+I Y + K F ++P +G Sbjct: 241 VFDRTLYTVKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 I + G +DFEE+ A++I V A+DKG P +AGH VLVEV+DVNDN P++ +TSLSLP+ Sbjct: 301 AITVIGHMDFEESRAHKIPVEAVDKGFPPLAGHCTVLVEVVDVNDNAPQLTLTSLSLPIP 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDAQ GTVI LISV DRD G NGQV CSLTP VPFKLVST+KNYYSLVLDSALDRESVSA Sbjct: 361 EDAQPGTVITLISVFDRDFGVNGQVTCSLTPRVPFKLVSTFKNYYSLVLDSALDRESVSA 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAG 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQKNALVSYSLVE RVGE ALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQKNALVSYSLVELRVGERALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GGAV ELVPRSVGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTGGAVRELVPRSVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQP A GA IPF VGLYTGEISTTR LDE DAPRHRLLVLVKDHGEP+LT Sbjct: 601 SGYNAWLSYELQPVAAGASIPFRVGLYTGEISTTRALDETDAPRHRLLVLVKDHGEPSLT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRAS+G PE LVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASLGIAGPETELVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 LRCSAP + C+ KPTLVCSSAVGSWS+SQQRRQRVCS E PPKTDLMAFSPSL Sbjct: 721 LRCSAPSSEGACSLVKPTLVCSSAVGSWSFSQQRRQRVCSGEGPPKTDLMAFSPSL 776 >gi|14165400 protocadherin alpha 1 isoform 2 precursor [Homo sapiens] Length = 807 Score = 1163 bits (3008), Expect = 0.0 Identities = 608/803 (75%), Positives = 669/803 (83%), Gaps = 4/803 (0%) Query: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 MV G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 V+VKDINDNPPVFR REQ + + ES L+S FP+EGA+DADIG N+LLTY LS ++ F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 ++ + S L LRK LDRE+TP+L+LLL DGGKPEL G+V++ ITVLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 FD+ Y+V L E N T V LNASD DEG+NGE+ + + + F ++ +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 EIR+ +LD+EE +YEIQV A+DKG P M+ H VLV+VLDVNDN PE+ VTSL LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQVSARDA Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQVSARDA 540 Query: 541 GVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDAD 600 GVPPLGSNVTLQVFVLDENDNAPALLA G GAVSELVPR VGAGHVVAKVRAVDAD Sbjct: 541 GVPPLGSNVTLQVFVLDENDNAPALLAPRVGGTIGAVSELVPRLVGAGHVVAKVRAVDAD 600 Query: 601 SGYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALT 660 SGYNAWLSYELQPAA GA IPF VGLYTGEISTTR+LDEAD R+RLLVLVKDHGEPALT Sbjct: 601 SGYNAWLSYELQPAAGGARIPFRVGLYTGEISTTRVLDEADLSRYRLLVLVKDHGEPALT 660 Query: 661 STATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA 720 +TATVLVSLVE+GQAPK SSRASVG PEAALVD+NVYLIIAICAVSSLLVLTLLLYTA Sbjct: 661 ATATVLVSLVESGQAPKASSRASVGVAGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTA 720 Query: 721 LRCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSLQLSR 780 LRCS PPT PGKPTLVCSSA+GSWS SQQRRQRVCS+E PPKTDLMAFSP L S Sbjct: 721 LRCSVPPTEGAYVPGKPTLVCSSALGSWSNSQQRRQRVCSSEGPPKTDLMAFSPGLSPS- 779 Query: 781 EDCLNPPSEPRQPNPDWRYSASL 803 LN QP + S ++ Sbjct: 780 ---LNTSERNEQPEANLDLSGNV 799 >gi|14165416 protocadherin alpha 5 isoform 2 precursor [Homo sapiens] Length = 816 Score = 1156 bits (2991), Expect = 0.0 Identities = 598/775 (77%), Positives = 657/775 (84%) Query: 2 VIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVP 61 ++ RG RLLL LLLA W+ GSGQLHYS+ EEAKHGTFVGRIAQDLGLELAELVP Sbjct: 1 MVYSRRGSLGSRLLLLWLLLAYWKAGSGQLHYSIPEEAKHGTFVGRIAQDLGLELAELVP 60 Query: 62 RLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDV 121 RLFRVASK GDLLEVNLQNGILFVNSRIDRE+LC R AECSIHLEVIVDRPLQVFHV+V Sbjct: 61 RLFRVASKGRGDLLEVNLQNGILFVNSRIDREELCRRRAECSIHLEVIVDRPLQVFHVEV 120 Query: 122 EVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELK 181 VKDINDNPP F +EQ++ + ES DS FPLEGASD DIG N+ L Y L+ NE F+L Sbjct: 121 AVKDINDNPPRFSRQEQRLFILESRMPDSRFPLEGASDLDIGANAQLRYRLNPNEYFDLD 180 Query: 182 IKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPA 241 +KT ++++ ELVLRK LDRE+T + LL++ DGGKPELTG+VQ+ I VLD NDN P Sbjct: 181 VKTNEEETNFLELVLRKSLDREETQEHRLLVIATDGGKPELTGTVQLLINVLDANDNAPE 240 Query: 242 FDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGE 301 FDK Y V L EN + T VI+LNASD DEG+N EI Y ++ K F IN +TGE Sbjct: 241 FDKSIYNVRLLENAPSGTLVIKLNASDADEGINKEIVYFFSNLVLDDVKSKFIINSNTGE 300 Query: 302 IRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQE 361 I++ GELD+E+ N+YEI ++A+DK ++GH V+V++LDVNDN PE+ +T+L LPV+E Sbjct: 301 IKVNGELDYEDYNSYEINIDAMDKSTFPLSGHCKVVVKLLDVNDNTPEMAITTLFLPVKE 360 Query: 362 DAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAY 421 DA + TVIALISVSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRESVS Y Sbjct: 361 DAPLSTVIALISVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESVSVY 420 Query: 422 ELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWD 481 ELVVTARDGGSPSLWATA VSVEVADVNDNAPAFAQP+YTVFVKENNPPGCHIFTVSA D Sbjct: 421 ELVVTARDGGSPSLWATASVSVEVADVNDNAPAFAQPQYTVFVKENNPPGCHIFTVSARD 480 Query: 482 ADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAG 541 ADAQ+NALVSYSLVERRVGE LSSYVSVHAESGKVYALQPLDHEE+ELLQFQVSARDAG Sbjct: 481 ADAQENALVSYSLVERRVGERPLSSYVSVHAESGKVYALQPLDHEEVELLQFQVSARDAG 540 Query: 542 VPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADS 601 VPPLGSNVTLQVFVLDENDNAPALL G GGAVSELVPRSVGAGHVVAKVRAVD DS Sbjct: 541 VPPLGSNVTLQVFVLDENDNAPALLVPRVGGTGGAVSELVPRSVGAGHVVAKVRAVDPDS 600 Query: 602 GYNAWLSYELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTS 661 GYNAWLSYELQPA A IPF VGLYTGEISTTR LDE +APRHRLLVLVKDHGEP LT+ Sbjct: 601 GYNAWLSYELQPAPGSARIPFRVGLYTGEISTTRSLDETEAPRHRLLVLVKDHGEPPLTA 660 Query: 662 TATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTAL 721 TATVLVSLVE+GQAPK SSRAS GAV PEAALVD+NVYLIIAICAVSSLLVLTLLLYTAL Sbjct: 661 TATVLVSLVESGQAPKASSRASAGAVGPEAALVDVNVYLIIAICAVSSLLVLTLLLYTAL 720 Query: 722 RCSAPPTVSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 RCSA PT + C GKPTL+CSSAVGSWSYSQQRRQRVCS E+PPKTDLMAFSPSL Sbjct: 721 RCSAQPTEAVCTRGKPTLLCSSAVGSWSYSQQRRQRVCSGEAPPKTDLMAFSPSL 775 >gi|7662068 protocadherin alpha 9 isoform 2 precursor [Homo sapiens] Length = 842 Score = 1150 bits (2975), Expect = 0.0 Identities = 599/768 (77%), Positives = 648/768 (84%) Query: 9 PGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVAS 68 P Q LLLSLL+LA W VGSGQLHYSV EEA+HGTFVGRIAQDLGLELAELVPRLF++ S Sbjct: 9 PEGQPLLLSLLILAMWVVGSGQLHYSVPEEAEHGTFVGRIAQDLGLELAELVPRLFQLDS 68 Query: 69 KRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 K GDLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND Sbjct: 69 KGRGDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVKDIND 128 Query: 129 NPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDK 188 NPPVF ++ + ++ES PLDS FPLEGASDADIG N+LLTY LS NE F L + T + Sbjct: 129 NPPVFPATQKNLFIAESRPLDSRFPLEGASDADIGENALLTYRLSPNEYFFLDVPTSNQQ 188 Query: 189 SILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYK 248 LVLRKLLDRE+TP+L+LLL DGGKPELTG+VQ+ ITVLD NDN P FD+ Y Sbjct: 189 VKPLGLVLRKLLDREETPELHLLLTATDGGKPELTGTVQLLITVLDNNDNAPVFDRTLYT 248 Query: 249 VVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGEL 308 V L ENV T VI NASD DEGLNG+I Y + K F ++P +G I + G + Sbjct: 249 VKLPENVSIGTLVIHPNASDLDEGLNGDIIYSFSSDVSPDIKSKFHMDPLSGAITVIGHM 308 Query: 309 DFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTV 368 DFEE+ A++I V A+DKG P +AGH +LVEV+DVNDN P++ + +LS+PV+EDAQ+GTV Sbjct: 309 DFEESRAHKIPVEAVDKGFPPLAGHCTLLVEVVDVNDNAPQLTIKTLSVPVKEDAQLGTV 368 Query: 369 IALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTAR 428 IALISV D D+ ANGQV CSLTPHVPFKLVSTYKNYYSLVLD ALDRESVSAYELVVTAR Sbjct: 369 IALISVIDLDADANGQVTCSLTPHVPFKLVSTYKNYYSLVLDRALDRESVSAYELVVTAR 428 Query: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNA 488 DGGSPSLWATARVSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSA DADAQ+NA Sbjct: 429 DGGSPSLWATARVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSARDADAQENA 488 Query: 489 LVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 LVSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN Sbjct: 489 LVSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSN 548 Query: 549 VTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLS 608 VTLQVFVLDENDNAPALL GAVSE+V RSVGAG VV KVRAVDADSGYNAWLS Sbjct: 549 VTLQVFVLDENDNAPALLTPRMRGTDGAVSEMVLRSVGAGVVVGKVRAVDADSGYNAWLS 608 Query: 609 YELQPAAVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVS 668 YELQP A IPF VGLYTGEISTTR LDE DAPR RLLVLVKDHGEPALT+TATVLVS Sbjct: 609 YELQPETASASIPFRVGLYTGEISTTRALDETDAPRQRLLVLVKDHGEPALTATATVLVS 668 Query: 669 LVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTALRCSAPPT 728 LVE+GQAPK+SSRASVGA PE LVD+NVYLIIAICAVSSLLVLTLLLYT LRCSA PT Sbjct: 669 LVESGQAPKSSSRASVGATGPEVTLVDVNVYLIIAICAVSSLLVLTLLLYTVLRCSAMPT 728 Query: 729 VSRCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTDLMAFSPSL 776 CAPGKPTLVCSSAVGSWSYSQQRRQRVCS E KTDLMAFSP L Sbjct: 729 EGECAPGKPTLVCSSAVGSWSYSQQRRQRVCSGEGKQKTDLMAFSPGL 776 >gi|14165383 protocadherin alpha 10 isoform 3 precursor [Homo sapiens] Length = 685 Score = 806 bits (2081), Expect = 0.0 Identities = 415/525 (79%), Positives = 446/525 (84%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLLSLLLLAAWEVGSGQLHYSVYEEA+HGTFVGRIAQDLGLELAELV RLFRVASK Sbjct: 9 GVQCLLLSLLLLAAWEVGSGQLHYSVYEEARHGTFVGRIAQDLGLELAELVQRLFRVASK 68 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 RHGDLLEVNLQNGILFVNSRIDRE+LCGRS ECSIHLEVIVDRPLQVFHVDVEVKDINDN Sbjct: 69 RHGDLLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDRPLQVFHVDVEVKDINDN 128 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP F EQK+ + ES LDS FPLEGASDAD+G N+LLTY LS NE F L I KKDK Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 P LVLRKLLDRE+ P+L LLL DGGKPE TGSV + I VLD NDN P FD+P Y+V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG+N E+ Y ++P + + F IN TGEI++ +D Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRKFWINERTGEIKVNDAID 308 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE++N YEI V+ DKG P M GH VLVE+LD NDN PEV+VTSLSLPV+EDAQVGTVI Sbjct: 309 FEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVTSLSLPVKEDAQVGTVI 368 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISVSD DSGANGQV CSLTPHVPFKLVSTYKNYYSLVLDSALDRE VSAYELVVTARD Sbjct: 369 ALISVSDHDSGANGQVTCSLTPHVPFKLVSTYKNYYSLVLDSALDRERVSAYELVVTARD 428 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSP LWATA VSVEVADVNDNAPAFAQ EYTVFVKENNPPGCHIFTVSAWDADAQ+NAL Sbjct: 429 GGSPPLWATASVSVEVADVNDNAPAFAQSEYTVFVKENNPPGCHIFTVSAWDADAQENAL 488 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVERR+GE +LSSYVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 489 VSYSLVERRLGERSLSSYVSVHAESGKVYALQPLDHEELELLQFQ 533 Score = 419 bits (1078), Expect = e-117 Identities = 286/666 (42%), Positives = 361/666 (54%), Gaps = 69/666 (10%) Query: 292 MFSINPDTGEIRIYGELDFEENNAYEIQVNA-----IDKGIPSMAGHSMVLVEVLDVNDN 346 + +N G + + +D EE ++ + +D+ P H V VEV D+NDN Sbjct: 73 LLEVNLQNGILFVNSRIDREELCGRSVECSIHLEVIVDR--PLQVFH--VDVEVKDINDN 128 Query: 347 VPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKN--- 403 P VT L + E + + L SD D G N + L+P+ F L K Sbjct: 129 PPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYFVLDIINKKDKD 188 Query: 404 -YYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTV 462 + LVL LDRE +L++TA DGG P + + + V D NDNAP F +P Y V Sbjct: 189 KFPVLVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILVLDANDNAPIFDRPVYEV 248 Query: 463 FVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQP 522 + EN + ++A D+D N + YS + + ++ +G++ Sbjct: 249 KMYENQVNQTLVIRLNASDSDEGINKEMMYSFSS--LVPPTIRRKFWINERTGEIKVNDA 306 Query: 523 LDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVP 582 +D E+ + V D G PP+ + T+ V +LDENDN+P ++ T ++S V Sbjct: 307 IDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIVT-------SLSLPVK 359 Query: 583 RSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVGAHIPFH-VGLYTGEISTTRILDEAD 641 G V+A + D DSG N ++ L P H+PF V Y S +LD A Sbjct: 360 EDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSL--VLDSA- 411 Query: 642 APRHRLLVLVKDHGEPALTSTATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLI 701 R R+ +A LV +G +P + ASV E A V+ N Sbjct: 412 LDRERV--------------SAYELVVTARDGGSPPLWATASVSV---EVADVNDNAPAF 454 Query: 702 IAICAVSSLLVLTLLLYTALRCSAPP-----TVSRCAPGKPTLVCSSAVGSWSYSQQRR- 755 A S V ++ + PP TVS +A+ S+S ++R Sbjct: 455 ----AQSEYTVF-------VKENNPPGCHIFTVSAWDADAQ----ENALVSYSLVERRLG 499 Query: 756 QRVCSAESPPKTDLMAFSPSLQLSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEE 815 +R S+ + L E+ +PRQPNPDWRYSASLRAGMHSSVHLEE Sbjct: 500 ERSLSSYVSVHAESGKVYALQPLDHEELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEE 559 Query: 816 AGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGEL 875 AGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGEL Sbjct: 560 AGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGEL 619 Query: 876 PDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNST 935 PDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNST Sbjct: 620 PDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNST 679 Query: 936 TDNSDQ 941 TDNSDQ Sbjct: 680 TDNSDQ 685 Score = 142 bits (357), Expect = 2e-33 Identities = 115/400 (28%), Positives = 179/400 (44%), Gaps = 28/400 (7%) Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKM---- 283 + + V D+NDN P F K+ + E+ D+R ASD D G N ++Y + Sbjct: 118 VDVEVKDINDNPPRFSVTEQKLSIPESRLLDSRFPLEGASDADVGENALLTYKLSPNEYF 177 Query: 284 ---ILPVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEV 340 I+ +K F + + + LD EEN ++ + A D G P G +L+ V Sbjct: 178 VLDIINKKDKDKFPV------LVLRKLLDREENPQLKLLLTATDGGKPEFTGSVSLLILV 231 Query: 341 LDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVST 400 LD NDN P + + E+ T++ ++ SD D G N +++ S + VP + Sbjct: 232 LDANDNAPIFDRPVYEVKMYENQVNQTLVIRLNASDSDEGINKEMMYSFSSLVPPTIRRK 291 Query: 401 Y---KNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQ 457 + + + ++ A+D E + YE+ V D G+P + V VE+ D NDN+P Sbjct: 292 FWINERTGEIKVNDAIDFEDSNTYEIHVDVTDKGNPPMVGHCTVLVELLDENDNSPEVIV 351 Query: 458 PEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKV 517 ++ VKE+ G I +S D D+ N V+ SL H VS + + Sbjct: 352 TSLSLPVKEDAQVGTVIALISVSDHDSGANGQVTCSLTP-----HVPFKLVSTYKNYYSL 406 Query: 518 YALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAV 577 LD E + + V+ARD G PPL + ++ V V D NDNAPA A Sbjct: 407 VLDSALDRERVSAYELVVTARDGGSPPLWATASVSVEVADVNDNAPAF-------AQSEY 459 Query: 578 SELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617 + V + G + V A DAD+ NA +SY L +G Sbjct: 460 TVFVKENNPPGCHIFTVSAWDADAQENALVSYSLVERRLG 499 >gi|14165394 protocadherin alpha 6 isoform 3 precursor [Homo sapiens] Length = 686 Score = 771 bits (1992), Expect = 0.0 Identities = 400/525 (76%), Positives = 441/525 (84%) Query: 10 GSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASK 69 G Q LLL LLLLAAW+VGSGQLHYSV EEAKHGTFVGRIAQDLGLELAELVPRLFR+ASK Sbjct: 10 GKQCLLLPLLLLAAWKVGSGQLHYSVPEEAKHGTFVGRIAQDLGLELAELVPRLFRMASK 69 Query: 70 RHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDN 129 DLLEVNLQNGILFVNSRIDRE+LCGRSAECSIHLEVIVDRPLQVFHVDVEV+DINDN Sbjct: 70 DREDLLEVNLQNGILFVNSRIDREELCGRSAECSIHLEVIVDRPLQVFHVDVEVRDINDN 129 Query: 130 PPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKS 189 PP+F EQ+V + ES DS FPLEGASDAD+G NS+LTY LS +E F L +K D + Sbjct: 130 PPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGLDVKINSDDN 189 Query: 190 ILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKV 249 L+L+K LDRE+ P NL L DGGKPELTG+VQ+ +TVLDVNDN P F++ Y+V Sbjct: 190 KQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAPTFEQSEYEV 249 Query: 250 VLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELD 309 + EN N T VI+LNASD DEG NG ISY ++ FSI+ +TGEI I G LD Sbjct: 250 RIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDRNTGEIVIRGNLD 309 Query: 310 FEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVI 369 FE+ N Y+I ++A DKG P MAGH VLV +LD NDNVPE+ +TSLSLPV+EDAQ GTVI Sbjct: 310 FEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSLPVREDAQFGTVI 369 Query: 370 ALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARD 429 ALISV+D DSGANGQV CSLTPHVPFKLVST+KNYYSLVLDSALDRESVSAYELVVTARD Sbjct: 370 ALISVNDLDSGANGQVNCSLTPHVPFKLVSTFKNYYSLVLDSALDRESVSAYELVVTARD 429 Query: 430 GGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNAL 489 GGSPSLWATA +SVEVAD+NDNAPAFAQPEYTVFVKENNPPGCHIFTVSA DADAQ+NAL Sbjct: 430 GGSPSLWATASLSVEVADMNDNAPAFAQPEYTVFVKENNPPGCHIFTVSARDADAQENAL 489 Query: 490 VSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 VSYSLVERRVGE ALSSY+SVHAESGKVYALQPLDHEELELLQFQ Sbjct: 490 VSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQ 534 Score = 435 bits (1118), Expect = e-121 Identities = 281/618 (45%), Positives = 347/618 (56%), Gaps = 66/618 (10%) Query: 338 VEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPF-- 395 VEV D+NDN P V + + E +V L SD D G+N + L+ F Sbjct: 121 VEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYFGL 180 Query: 396 --KLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAP 453 K+ S L+L +LDRE A+ L +TA DGG P L T ++ V V DVNDNAP Sbjct: 181 DVKINSDDNKQIGLLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVNDNAP 240 Query: 454 AFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYS---LVERRVGEHALSSYVSV 510 F Q EY V + EN G + ++A D D N +SYS LV V +H S+ Sbjct: 241 TFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDH-----FSI 295 Query: 511 HAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPA 570 +G++ LD E+ L + + A D G PP+ + T+ V +LD+NDN P + T Sbjct: 296 DRNTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALT-- 353 Query: 571 GSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVGAHIPFHVGLYTGE 630 ++S V G V+A + D DSG N ++ L P H+PF + Sbjct: 354 -----SLSLPVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKL------ 397 Query: 631 ISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSLVENGQAPKTSSRASVGAVDPE 690 +ST + LV D + +A LV +G +P + AS+ Sbjct: 398 VSTFK----------NYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATASLSV---- 443 Query: 691 AALVDINVYLIIAICAVSSLLVLTLLLYTA-LRCSAPP-----TVSRCAPGKPTLVCSSA 744 + D+N + YT ++ + PP TVS + +A Sbjct: 444 -EVADMN----------DNAPAFAQPEYTVFVKENNPPGCHIFTVS----ARDADAQENA 488 Query: 745 VGSWSYSQQR-RQRVCSAESPPKTDLMAFSPSLQLSREDCLNPPSEPRQPNPDWRYSASL 803 + S+S ++R +R S+ + L E+ +PRQPNPDWRYSASL Sbjct: 489 LVSYSLVERRVGERALSSYISVHAESGKVYALQPLDHEELELLQFQPRQPNPDWRYSASL 548 Query: 804 RAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYG 863 RAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYG Sbjct: 549 RAGMHSSVHLEEAGILRAGPGGPDQQWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYG 608 Query: 864 PGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGN 923 PGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGN Sbjct: 609 PGNPKQSGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGN 668 Query: 924 KTQEKKEKGNSTTDNSDQ 941 KTQEKKEKGNSTTDNSDQ Sbjct: 669 KTQEKKEKGNSTTDNSDQ 686 Score = 156 bits (395), Expect = 7e-38 Identities = 121/395 (30%), Positives = 179/395 (45%), Gaps = 18/395 (4%) Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKM--IL 285 + + V D+NDN P F +V++ E+ D+ ASD D G N ++Y + Sbjct: 119 VDVEVRDINDNPPLFPVEEQRVLIYESRLPDSVFPLEGASDADVGSNSILTYKLSSSEYF 178 Query: 286 PVSEKCMFSINPDTGEIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVND 345 + K N G + + LD EE A+ + + A D G P + G +LV VLDVND Sbjct: 179 GLDVKINSDDNKQIG-LLLKKSLDREEAPAHNLFLTATDGGKPELTGTVQLLVTVLDVND 237 Query: 346 NVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTY---K 402 N P + + + E+A GT + ++ SDRD GANG + S V ++ + + Sbjct: 238 NAPTFEQSEYEVRIFENADNGTTVIRLNASDRDEGANGAISYSFNSLVAAMVIDHFSIDR 297 Query: 403 NYYSLVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTV 462 N +V+ LD E + Y++++ A D G P + V V + D NDN P A ++ Sbjct: 298 NTGEIVIRGNLDFEQENLYKILIDATDKGHPPMAGHCTVLVRILDKNDNVPEIALTSLSL 357 Query: 463 FVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQP 522 V+E+ G I +S D D+ N V+ SL H VS + Sbjct: 358 PVREDAQFGTVIALISVNDLDSGANGQVNCSLTP-----HVPFKLVSTFKNYYSLVLDSA 412 Query: 523 LDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVP 582 LD E + + V+ARD G P L + +L V V D NDNAPA A + V Sbjct: 413 LDRESVSAYELVVTARDGGSPSLWATASLSVEVADMNDNAPAF-------AQPEYTVFVK 465 Query: 583 RSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617 + G + V A DAD+ NA +SY L VG Sbjct: 466 ENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500 >gi|14165402 protocadherin alpha 1 isoform 3 precursor [Homo sapiens] Length = 686 Score = 758 bits (1958), Expect = 0.0 Identities = 392/534 (73%), Positives = 443/534 (82%) Query: 1 MVIIGPRGPGSQRLLLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELV 60 MV G G++ LLL LLLLAAWEVGSGQLHYS+ EEAKHGTFVGR+AQDLGLELAELV Sbjct: 1 MVFSRRGGLGARDLLLWLLLLAAWEVGSGQLHYSIPEEAKHGTFVGRVAQDLGLELAELV 60 Query: 61 PRLFRVASKRHGDLLEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVD 120 PRLFRVASK H DLLEVNLQNGILFVNSRIDRE+LC SAECSIHLE+I DRPLQVFHV+ Sbjct: 61 PRLFRVASKTHRDLLEVNLQNGILFVNSRIDREELCQWSAECSIHLELIADRPLQVFHVE 120 Query: 121 VEVKDINDNPPVFREREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFEL 180 V+VKDINDNPPVFR REQ + + ES L+S FP+EGA+DADIG N+LLTY LS ++ F L Sbjct: 121 VKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTLSPSDYFSL 180 Query: 181 KIKTKKDKSILPELVLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGP 240 ++ + S L LRK LDRE+TP+L+LLL DGGKPEL G+V++ ITVLDVNDN P Sbjct: 181 DVEASDELSKSLWLELRKYLDREETPELHLLLTATDGGKPELQGTVELLITVLDVNDNAP 240 Query: 241 AFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTG 300 FD+ Y+V L E N T V LNASD DEG+NGE+ + + + F ++ +G Sbjct: 241 LFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQEKFKVDSSSG 300 Query: 301 EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQ 360 EIR+ +LD+EE +YEIQV A+DKG P M+ H VLV+VLDVNDN PE+ VTSL LP++ Sbjct: 301 EIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPELAVTSLYLPIR 360 Query: 361 EDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSA 420 EDA + TVIALI+VSDRDSGANGQV CSL PHVPFKLVST+KNYYSLVLDSALDRES+S Sbjct: 361 EDAPLSTVIALITVSDRDSGANGQVTCSLMPHVPFKLVSTFKNYYSLVLDSALDRESLSV 420 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSA Sbjct: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAR 480 Query: 481 DADAQKNALVSYSLVERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQ 534 DADAQ+NALVSYSLVERRVGE ALS+YVSVHAESGKVYALQPLDHEELELLQFQ Sbjct: 481 DADAQENALVSYSLVERRVGERALSNYVSVHAESGKVYALQPLDHEELELLQFQ 534 Score = 434 bits (1115), Expect = e-121 Identities = 300/713 (42%), Positives = 379/713 (53%), Gaps = 90/713 (12%) Query: 263 QLNASDPDEGLNG------------EISYGIKMILPVSEKC---MFSINPDTGEIRIYGE 307 QL+ S P+E +G E++ + + V+ K + +N G + + Sbjct: 30 QLHYSIPEEAKHGTFVGRVAQDLGLELAELVPRLFRVASKTHRDLLEVNLQNGILFVNSR 89 Query: 308 LDFEENNAYEIQVNAIDKGI---PSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQ 364 +D EE + + + + I P H V V+V D+NDN P + + E Sbjct: 90 IDREELCQWSAECSIHLELIADRPLQVFH--VEVKVKDINDNPPVFRGREQIIFIPESRL 147 Query: 365 VGTVIALISVSDRDSGANGQVICSLTPHVPFKLVSTYKNYYS----LVLDSALDRESVSA 420 + + + +D D GAN + +L+P F L + S L L LDRE Sbjct: 148 LNSRFPIEGAADADIGANALLTYTLSPSDYFSLDVEASDELSKSLWLELRKYLDREETPE 207 Query: 421 YELVVTARDGGSPSLWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAW 480 L++TA DGG P L T + + V DVNDNAP F Q Y V + E G + T++A Sbjct: 208 LHLLLTATDGGKPELQGTVELLITVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNAS 267 Query: 481 DADAQKNALVSYSL---VERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSA 537 DAD N V +S + R + E V + SG++ + LD+EE + + QV A Sbjct: 268 DADEGVNGEVVFSFDSGISRDIQEK-----FKVDSSSGEIRLIDKLDYEETKSYEIQVKA 322 Query: 538 RDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAV 597 D G PP+ ++ + V VLD NDNAP L T S + E P S V+A + Sbjct: 323 VDKGSPPMSNHCKVLVKVLDVNDNAPELAVT---SLYLPIREDAPLST----VIALITVS 375 Query: 598 DADSGYNAWLSYELQPAAVGAHIPFH-VGLYTGEISTT--RILDEADAPRHRLLVLVKDH 654 D DSG N ++ L P H+PF V + S LD + L+V +D Sbjct: 376 DRDSGANGQVTCSLMP-----HVPFKLVSTFKNYYSLVLDSALDRESLSVYELVVTARDG 430 Query: 655 GEPALTSTATVLVSLVENGQAPKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLT 714 G P+L +TA V V + A V P A + V++ Sbjct: 431 GSPSLWATARVSVEV------------ADVNDNAPAFAQPEYTVFV-------------- 464 Query: 715 LLLYTALRCSAPP-----TVS-RCAPGKPTLVCSSAVGSWSYSQQRRQRVCSAESPPKTD 768 + + PP TVS R A + + S ++ ++ S + Sbjct: 465 -------KENNPPGCHIFTVSARDADAQENALVSYSLVERRVGERALSNYVSVHAE-SGK 516 Query: 769 LMAFSPSLQLSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ 828 + A P L E+ +PRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ Sbjct: 517 VYALQP---LDHEELELLQFQPRQPNPDWRYSASLRAGMHSSVHLEEAGILRAGPGGPDQ 573 Query: 829 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII 888 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII Sbjct: 574 QWPTVSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQSGPGELPDKFIIPGSPAII 633 Query: 889 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 941 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ Sbjct: 634 SIRQEPTNSQIDKSDFITFGKKEETKKKKKKKKGNKTQEKKEKGNSTTDNSDQ 686 Score = 149 bits (376), Expect = 1e-35 Identities = 122/402 (30%), Positives = 181/402 (45%), Gaps = 32/402 (7%) Query: 228 IQITVLDVNDNGPAFDKPSYKVVLSENVQNDTRVIQLNASDPDEGLNGEISYGIKMILPV 287 +++ V D+NDN P F + + E+ ++R A+D D G N ++Y + Sbjct: 119 VEVKVKDINDNPPVFRGREQIIFIPESRLLNSRFPIEGAADADIGANALLTYTL------ 172 Query: 288 SEKCMFSINPDTG---------EIRIYGELDFEENNAYEIQVNAIDKGIPSMAGHSMVLV 338 S FS++ + E+R Y LD EE + + A D G P + G +L+ Sbjct: 173 SPSDYFSLDVEASDELSKSLWLELRKY--LDREETPELHLLLTATDGGKPELQGTVELLI 230 Query: 339 EVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISVSDRDSGANGQVICSLTPHVPFKLV 398 VLDVNDN P + + E GT++ ++ SD D G NG+V+ S + + Sbjct: 231 TVLDVNDNAPLFDQAVYRVHLLETTANGTLVTTLNASDADEGVNGEVVFSFDSGISRDIQ 290 Query: 399 STYKNYYS---LVLDSALDRESVSAYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF 455 +K S + L LD E +YE+ V A D GSP + +V V+V DVNDNAP Sbjct: 291 EKFKVDSSSGEIRLIDKLDYEETKSYEIQVKAVDKGSPPMSNHCKVLVKVLDVNDNAPEL 350 Query: 456 AQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSLVERRVGEHALSSYVSVHAESG 515 A + ++E+ P I ++ D D+ N V+ SL+ H VS Sbjct: 351 AVTSLYLPIREDAPLSTVIALITVSDRDSGANGQVTCSLMP-----HVPFKLVSTFKNYY 405 Query: 516 KVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVFVLDENDNAPALLATPAGSAGG 575 + LD E L + + V+ARD G P L + + V V D NDNAPA A Sbjct: 406 SLVLDSALDRESLSVYELVVTARDGGSPSLWATARVSVEVADVNDNAPAF-------AQP 458 Query: 576 AVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPAAVG 617 + V + G + V A DAD+ NA +SY L VG Sbjct: 459 EYTVFVKENNPPGCHIFTVSARDADAQENALVSYSLVERRVG 500 >gi|11128023 protocadherin gamma subfamily C, 5 isoform 1 precursor [Homo sapiens] Length = 944 Score = 605 bits (1559), Expect = e-173 Identities = 361/950 (38%), Positives = 534/950 (56%), Gaps = 65/950 (6%) Query: 15 LLSLLLLAAWEVGSGQLHYSVYEEAKHGTFVGRIAQDLGLELAELVPRLFRVASKRHGDL 74 +L +L L W SGQL YSV EE++ GT VG +AQDLGL++ +L+ R ++ S+ +G Sbjct: 15 VLCMLSLCCWGWVSGQLRYSVVEESEPGTLVGNVAQDLGLKMTDLLSRRLQLGSEENGRY 74 Query: 75 LEVNLQNGILFVNSRIDREKLCGRSAECSIHLEVIVDRPLQVFHVDVEVKDINDNPPVFR 134 ++L +G L VN +IDRE LCG S C + ++V+ + PL++ V+VE+ D+NDN P F Sbjct: 75 FSLSLMSGALAVNQKIDRESLCGASTSCLLPVQVVTEHPLELIRVEVEILDLNDNSPSFA 134 Query: 135 EREQKVPVSESAPLDSHFPLEGASDADIGVNSLLTYALSLNENFELKIKTKKDKSILPEL 194 E+++ +SESA + FPL+ A D D+G N++ Y LS N +F L +KT KD PEL Sbjct: 135 TPEREMRISESAASGARFPLDSAQDPDVGTNTVSFYTLSPNSHFSLNVKTLKDGKPFPEL 194 Query: 195 VLRKLLDREQTPKLNLLLMVIDGGKPELTGSVQIQITVLDVNDNGPAFDKPSYKVVLSEN 254 VL + LDRE + L+L +DGG P +G+ I + VLD+NDN P F +V + EN Sbjct: 195 VLEQQLDREAQARHQLVLTAVDGGTPARSGTTLISVIVLDINDNAPTFQSSVLRVGIPEN 254 Query: 255 VQNDTRVIQLNASDPDEGLNGEISYGIKMILPVSEKCMFSINPDTGEIRIYGELDFEENN 314 T +++LNA+DPDEG NG++ Y + + +F ++P +G I + G +DFEE+ Sbjct: 255 APIGTLLLRLNATDPDEGTNGQLDYSFGDHTSEAVRNLFGLDPSSGAIHVLGPIDFEESR 314 Query: 315 AYEIQVNAIDKGIPSMAGHSMVLVEVLDVNDNVPEVMVTSLSLPVQEDAQVGTVIALISV 374 YEI A D+G P+M GH ++ V+V DVNDN PEV++ SL+ PV E VGTV+ L +V Sbjct: 315 FYEIHARARDQGQPAMEGHCVIQVDVGDVNDNAPEVLLASLANPVLESTPVGTVVGLFNV 374 Query: 375 SDRDSGANGQVICSLTPHVPFKLVSTYKNYYSLVLDSALDRESVSAYELVVTARDGGSPS 434 DRDSG NG+V ++P +PF+ + +N+YSL+ LDRE+ S Y + + A D GSPS Sbjct: 375 RDRDSGRNGEVSLDISPDLPFQ-IKPSENHYSLLTSQPLDREATSHYIIELLASDAGSPS 433 Query: 435 LWATARVSVEVADVNDNAPAFAQPEYTVFVKENNPPGCHIFTVSAWDADAQKNALVSYSL 494 L + + ++DVNDNAP F Q YT ++ EN PPG + TV+A D D NA ++YS+ Sbjct: 434 LHKHLTIRLNISDVNDNAPRFNQQLYTAYILENRPPGSLLCTVAASDPDTGDNARLTYSI 493 Query: 495 VERRVGEHALSSYVSVHAESGKVYALQPLDHEELELLQFQVSARDAGVPPLGSNVTLQVF 554 V +V SS+V V+ E G+++A + D+E L++LQ V RD+G PPL +N +L VF Sbjct: 494 VGNQVQGAPASSFVYVNPEDGRIFAQRTFDYELLQMLQIVVGVRDSGSPPLHANTSLHVF 553 Query: 555 VLDENDNAPALLATPAGSAGGAVSELVPRSVGAGHVVAKVRAVDADSGYNAWLSYELQPA 614 VLDENDNAPA+L P + + +PRS G +V KV AVDAD+G+NAWLSY L P Sbjct: 554 VLDENDNAPAVL-HPRPDWEHSAPQRLPRSAPPGSLVTKVTAVDADAGHNAWLSYSLLPQ 612 Query: 615 AVGAHIPFHVGLYTGEISTTRILDEADAPRHRLLVLVKDHGEPALTSTATVLVSLVENGQ 674 + + F V +TGE+ T R L E D+ +++VLV+D+G+P+L+STATVL LV + Sbjct: 613 STAPGL-FLVSTHTGEVRTARALLEDDSDTQQVVVLVRDNGDPSLSSTATVL--LVLEDE 669 Query: 675 APKTSSRASVGAVDPEAALVDINVYLIIAICAVSSLLVLTLLLYTA-------------- 720 P+ ++S + P D+ +YLI+A+ VS L ++T +A Sbjct: 670 DPEEMPKSSDFLIHPPER-SDLTLYLIVALATVSLLSLVTFTFLSAKCLQGNADGDGGGG 728 Query: 721 --LRCSAPPTVSRCAPGKPTLVCSSAVGSWSY---------SQQRRQRVCSAESPPKTDL 769 R P+ P L SS G+ Y SQ R C + + +D Sbjct: 729 QCCRRQDSPSPDFYKQSSPNLQVSSD-GTLKYMEVTLRPTDSQSHCYRTCFSPASDGSDF 787 Query: 770 -------------MAFSPSLQLSREDCLNPPSEPRQPNPDWRYSASLRAGMHSSVHLEEA 816 +A P SR + L S+ PN DWR+S + R G S + ++ Sbjct: 788 TFLRPLSVQQPTALALEPDAIRSRSNTLRERSQQAPPNTDWRFSQAQRPGTSGSQNGDDT 847 Query: 817 GILRAGPGGPDQQWPT-------VSSATPEPEAGEVSPPVGAGVNSNSWTFKYGPGNPKQ 869 G P+ Q+ T ++SA+ EA + S +G G + + +YGP Q Sbjct: 848 GT------WPNNQFDTEMLQAMILASAS---EAADGSSTLGGGAGTMGLSARYGPQFTLQ 898 Query: 870 SGPGELPDKFIIPGSPAIISIRQEPTNSQIDKSDFITFGKKEETKKKKKK 919 P + IPGS A ++ + K+ G K+++ KK+KK Sbjct: 899 HVP-DYRQNVYIPGSNATLT---NAAGKRDGKAPAGGNGNKKKSGKKEKK 944 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.314 0.132 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,915,540 Number of Sequences: 37866 Number of extensions: 1960239 Number of successful extensions: 14761 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 215 Number of HSP's successfully gapped in prelim test: 63 Number of HSP's that attempted gapping in prelim test: 7255 Number of HSP's gapped (non-prelim): 1228 length of query: 941 length of database: 18,247,518 effective HSP length: 112 effective length of query: 829 effective length of database: 14,006,526 effective search space: 11611410054 effective search space used: 11611410054 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.