Search of human proteins with 91208420

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|91208420 bassoon protein [Homo sapiens]
         (3926 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|91208420 bassoon protein [Homo sapiens]                           7946   0.0  
gi|150170670 piccolo isoform 2 [Homo sapiens]                         737   0.0  
gi|150378539 piccolo isoform 1 [Homo sapiens]                         737   0.0  
gi|163965366 nascent polypeptide-associated complex alpha subuni...   114   2e-24
gi|188536004 zinc finger protein 469 [Homo sapiens]                    99   6e-20
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    98   1e-19
gi|239743293 PREDICTED: mucin 12 [Homo sapiens]                        97   4e-19
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   91   2e-17
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   91   2e-17
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   87   2e-16
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    87   2e-16
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         87   2e-16
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        87   3e-16
gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Hom...    86   9e-16
gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Hom...    86   9e-16
gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo sap...    86   9e-16
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    83   5e-15
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]             82   1e-14
gi|78042577 MAP7 domain containing 1 [Homo sapiens]                    81   2e-14
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    80   3e-14
gi|112421108 capicua homolog [Homo sapiens]                            77   3e-13
gi|116284392 mucin 2 precursor [Homo sapiens]                          77   4e-13
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         77   4e-13
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     76   6e-13
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          76   8e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    75   1e-12
gi|221139761 zinc finger protein 853 [Homo sapiens]                    75   1e-12
gi|60097902 filaggrin [Homo sapiens]                                   75   1e-12
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f...    73   6e-12
gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d...    73   6e-12

>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 7946 bits (20617), Expect = 0.0
 Identities = 3926/3926 (100%), Positives = 3926/3926 (100%)

Query: 1    MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPV 60
            MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPV
Sbjct: 1    MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPV 60

Query: 61   PGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQ 120
            PGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQ
Sbjct: 61   PGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQ 120

Query: 121  EADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTS 180
            EADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTS
Sbjct: 121  EADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTS 180

Query: 181  TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQ 240
            TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQ
Sbjct: 181  TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQ 240

Query: 241  QLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVG 300
            QLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVG
Sbjct: 241  QLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVG 300

Query: 301  RVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQ 360
            RVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQ
Sbjct: 301  RVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQ 360

Query: 361  ASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARM 420
            ASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARM
Sbjct: 361  ASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARM 420

Query: 421  GPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPA 480
            GPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPA
Sbjct: 421  GPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPA 480

Query: 481  NYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPP 540
            NYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPP
Sbjct: 481  NYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPP 540

Query: 541  VGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSK 600
            VGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSK
Sbjct: 541  VGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSK 600

Query: 601  TPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE 660
            TPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE
Sbjct: 601  TPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE 660

Query: 661  AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS 720
            AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS
Sbjct: 661  AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS 720

Query: 721  PSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDI 780
            PSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDI
Sbjct: 721  PSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDI 780

Query: 781  LEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDE 840
            LEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDE
Sbjct: 781  LEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDE 840

Query: 841  DFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHN 900
            DFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHN
Sbjct: 841  DFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHN 900

Query: 901  ATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP 960
            ATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP
Sbjct: 901  ATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP 960

Query: 961  ELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAK 1020
            ELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAK
Sbjct: 961  ELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAK 1020

Query: 1021 QQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEE 1080
            QQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEE
Sbjct: 1021 QQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEE 1080

Query: 1081 LRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALD 1140
            LRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALD
Sbjct: 1081 LRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALD 1140

Query: 1141 GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQR 1200
            GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQR
Sbjct: 1141 GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQR 1200

Query: 1201 QQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEI 1260
            QQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEI
Sbjct: 1201 QQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEI 1260

Query: 1261 LQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAP 1320
            LQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAP
Sbjct: 1261 LQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAP 1320

Query: 1321 VSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGT 1380
            VSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGT
Sbjct: 1321 VSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGT 1380

Query: 1381 PATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
            PATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS
Sbjct: 1381 PATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
            GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA
Sbjct: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500

Query: 1501 TAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVIT 1560
            TAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVIT
Sbjct: 1501 TAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVIT 1560

Query: 1561 LASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPS 1620
            LASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPS
Sbjct: 1561 LASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPS 1620

Query: 1621 AGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILT 1680
            AGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILT
Sbjct: 1621 AGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILT 1680

Query: 1681 DQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSV 1740
            DQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSV
Sbjct: 1681 DQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSV 1740

Query: 1741 FMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFA 1800
            FMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFA
Sbjct: 1741 FMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFA 1800

Query: 1801 RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKP 1860
            RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKP
Sbjct: 1801 RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKP 1860

Query: 1861 HTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPA 1920
            HTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPA
Sbjct: 1861 HTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPA 1920

Query: 1921 PSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRL 1980
            PSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRL
Sbjct: 1921 PSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRL 1980

Query: 1981 YSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYG 2040
            YSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYG
Sbjct: 1981 YSSMSDTNLAEAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYG 2040

Query: 2041 SVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISR 2100
            SVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISR
Sbjct: 2041 SVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISR 2100

Query: 2101 MCAALNSMDQYGGRHGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPS 2160
            MCAALNSMDQYGGRHGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPS
Sbjct: 2101 MCAALNSMDQYGGRHGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPS 2160

Query: 2161 PGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMV 2220
            PGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMV
Sbjct: 2161 PGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMV 2220

Query: 2221 RGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPV 2280
            RGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPV
Sbjct: 2221 RGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPV 2280

Query: 2281 YLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADA 2340
            YLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADA
Sbjct: 2281 YLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADA 2340

Query: 2341 APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVE 2400
            APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVE
Sbjct: 2341 APGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVE 2400

Query: 2401 LQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQ 2460
            LQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQ
Sbjct: 2401 LQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQ 2460

Query: 2461 QLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLG 2520
            QLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLG
Sbjct: 2461 QLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLG 2520

Query: 2521 QPREPVLHRGLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580
            QPREPVLHRGLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI
Sbjct: 2521 QPREPVLHRGLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580

Query: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSDSG 2640
            ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSDSG
Sbjct: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSDSG 2640

Query: 2641 SDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEI 2700
            SDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEI
Sbjct: 2641 SDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEI 2700

Query: 2701 VRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEK 2760
            VRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEK
Sbjct: 2701 VRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEK 2760

Query: 2761 KKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKA 2820
            KKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKA
Sbjct: 2761 KKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKA 2820

Query: 2821 HVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQ 2880
            HVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQ
Sbjct: 2821 HVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQ 2880

Query: 2881 VSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASL 2940
            VSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASL
Sbjct: 2881 VSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASL 2940

Query: 2941 LRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYP 3000
            LRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYP
Sbjct: 2941 LRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYP 3000

Query: 3001 PLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPA 3060
            PLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPA
Sbjct: 3001 PLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPA 3060

Query: 3061 PQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAG 3120
            PQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAG
Sbjct: 3061 PQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAG 3120

Query: 3121 QTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSY 3180
            QTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSY
Sbjct: 3121 QTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSY 3180

Query: 3181 SGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL 3240
            SGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL
Sbjct: 3181 SGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL 3240

Query: 3241 TKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRG 3300
            TKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRG
Sbjct: 3241 TKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRG 3300

Query: 3301 KGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKH 3360
            KGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKH
Sbjct: 3301 KGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKH 3360

Query: 3361 RKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQ 3420
            RKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQ
Sbjct: 3361 RKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQ 3420

Query: 3421 KYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAG 3480
            KYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAG
Sbjct: 3421 KYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAG 3480

Query: 3481 PKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDV 3540
            PKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDV
Sbjct: 3481 PKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDV 3540

Query: 3541 QEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGG 3600
            QEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGG
Sbjct: 3541 QEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGG 3600

Query: 3601 HAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGE 3660
            HAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGE
Sbjct: 3601 HAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGE 3660

Query: 3661 EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD 3720
            EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD
Sbjct: 3661 EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD 3720

Query: 3721 SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQ 3780
            SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQ
Sbjct: 3721 SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQ 3780

Query: 3781 QQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAE 3840
            QQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAE
Sbjct: 3781 QQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAE 3840

Query: 3841 QTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKIL 3900
            QTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKIL
Sbjct: 3841 QTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKIL 3900

Query: 3901 PGGAAEQAGKLTEAVSAFGKKFSSFW 3926
            PGGAAEQAGKLTEAVSAFGKKFSSFW
Sbjct: 3901 PGGAAEQAGKLTEAVSAFGKKFSSFW 3926


>gi|150170670 piccolo isoform 2 [Homo sapiens]
          Length = 4935

 Score =  737 bits (1903), Expect = 0.0
 Identities = 555/1506 (36%), Positives = 790/1506 (52%), Gaps = 199/1506 (13%)

Query: 2185 ATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRV 2244
            + +R+++G++YS++ TP  +T  ITTQP S+    VR        SG  TA  +TSL   
Sbjct: 3080 SVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRD------LSGIHTADAVTSL--- 3130

Query: 2245 PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPV- 2303
                      P   +  P P  + I +                       G S  ++ V 
Sbjct: 3131 ----------PAMHHSQPMPRSYFITT-----------------------GASETDIAVT 3157

Query: 2304 GAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEE 2363
            G      L T T  ++        P      +   +   G  S  L  P  +K       
Sbjct: 3158 GIDISASLQTITMESLTAETIDSVPTLTTASEVFPEVV-GDESALLIVPEEDK------- 3209

Query: 2364 RQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIK 2423
                 Q+Q L LERE +ELEK++Q R  EELE ER E+QR RE+E+++VQ++L+ELQ++K
Sbjct: 3210 -----QQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMK 3264

Query: 2424 HHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPF---PAA 2480
             H+L QQ+EERQAQF +++E LAQQ+LQLEQIQQLQQQL QQLEEQK RQ   +   P+ 
Sbjct: 3265 QHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSG 3324

Query: 2481 CEAPGRGPPLAAAE----LAQNGQYW----PPLTHAAFIAMAGPEGLG-------QPREP 2525
              +P      A  E      +  Q+W       T +A +A+  P+  G          + 
Sbjct: 3325 TASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQY 3384

Query: 2526 VLHRGLPSSAS-----DMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580
            +   G+ S+ S     D+ ++ E+Q +   SG K R     + +        +P   ++I
Sbjct: 3385 IAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDDMGE----NMTDDPRSFKKI 3440

Query: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVR-RRRSRLPRHSDS 2639
             DS VQTDDED   R  +SRRRR ++S D SVQTDDED  EW+ P R RR++R+ ++ DS
Sbjct: 3441 VDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDS 3500

Query: 2640 GSDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVE 2699
             +++  D T   S        +SS+ +QT+++ SVQTEP    R +P+I   A  D KVE
Sbjct: 3501 MTEA--DKTKPLSK-------VSSIAVQTVAEISVQTEPVGTIR-TPSIR--ARVDAKVE 3548

Query: 2700 IVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFE 2759
            I+++ISAPEKT +G SL CQTE D   Q    PQ +  T+                   +
Sbjct: 3549 IIKHISAPEKTYKGGSLGCQTEADSDTQ---SPQYLSATSPPK----------------D 3589

Query: 2760 KKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNK 2819
            KK+P PLEIGY +HL  +S  QL +  PPKSP+VLYSP+SPLSP + L+++F   E+   
Sbjct: 3590 KKRPTPLEIGYSSHLRADSTVQL-APSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLP 3648

Query: 2820 AHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGS 2879
              +SPQK    D A      P+  K +QRS+SDPKPLSPTA+ES++  F   +     GS
Sbjct: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS 3708

Query: 2880 QVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKAS 2939
            Q   +  +   +KVKRTLP+PPPEE      G  S      ++ +R +    T+   +A 
Sbjct: 3709 Q--TMTSSGAQKKVKRTLPNPPPEEIS---TGTQSTFSTMGTVSRRRICRTNTM--ARAK 3761

Query: 2940 LLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDY 2999
            +L+++DR+L LVE ES KLRKKQAELDEEEKEIDAKL+YLE+GI +RKE+L K+R  R+ 
Sbjct: 3762 ILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRER 3821

Query: 3000 PPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPP 3059
              L+G+ E RDY+SDSE++  R     +  G  ++ P TA         T F Q  F PP
Sbjct: 3822 AYLQGVAEDRDYMSDSEVSSTRPTRIESQHG--IERPRTAP-------QTEFSQ--FIPP 3870

Query: 3060 APQYSAGSGGPT------QNGFPA--HQAPT-YPGPSTYPAPAFPPGASYPAEPGLPNQQ 3110
              Q  +    PT      Q   PA   QAPT Y   S +           P +   P  Q
Sbjct: 3871 QTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQT-QPTFQ 3929

Query: 3111 AFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVP 3170
            A           P PT Q + + +P+      QKPRQT+L  LE K+ +NYEVI +   P
Sbjct: 3930 AVATMSFTPQVQPTPTPQPS-YQLPSQMMVIQQKPRQTTLY-LEPKITSNYEVIRNQ--P 3985

Query: 3171 MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRN 3230
            +  AP  T  +      G +   +       +R S++ SP  +  +DS Y  ++ + PRN
Sbjct: 3986 LMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRN 4045

Query: 3231 YVMIDDISELTKDST--STA-----PDSQRLEPLGPGSSGRPGKEPGE-PGVLDGPTLPC 3282
            YV+IDDI E+TK +   STA      D  + + L   +  R  +E  +    L   +   
Sbjct: 4046 YVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRLH 4105

Query: 3283 CYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTH-------YYGDSDYRHGARVEKYG 3335
             Y + EE+  ED Y+ +     ++     G  +  H       Y+ D+ YRH  + EKY 
Sbjct: 4106 SYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYYHADTSYRHFPKSEKYS 4165

Query: 3336 PGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVS 3394
               +   K  +K L  A +  K+SKH+K  ++ K+SKFSPI+E++D+E D +SY   + S
Sbjct: 4166 ISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYMTSSTS 4225

Query: 3395 S--SLVSRGRKFQDEITYGLKKNVYEQQKYYGMS-----------SRDAVED--DRIYGG 3439
            S   + SR R  QD+IT+GL+KN+ +QQK+ G S            R A++D  D+ Y  
Sbjct: 4226 SIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSS 4285

Query: 3440 SSRSR---APSAYSGEKLS-SHDFSGWGKGYE-REREAVE-----RLQKAGPKPSSLSMA 3489
             SRSR    PS+  G  LS   D S      + +E EA++         A  KP+SL ++
Sbjct: 4286 GSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPIS 4345

Query: 3490 HSRVRPPMRSQASEEESPVSPLGRP----RPAGGPLPP-GGDTCPQFCSSHSMPDVQEHV 3544
             SR R P+ +Q SEEESP+SP+G+P    R A GPLPP   DT  QF SSHS+P+VQ+H+
Sbjct: 4346 QSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHM 4405

Query: 3545 KDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVS 3604
            ++  R   Y R+  +I+DD    +SDSEAYHL +EETDWFDKPR++R +      GH + 
Sbjct: 4406 REESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLE-----NGHGLD 4460

Query: 3605 SSSQKR 3610
                +R
Sbjct: 4461 RKLPER 4466



 Score =  583 bits (1504), Expect = e-166
 Identities = 566/1914 (29%), Positives = 804/1914 (42%), Gaps = 324/1914 (16%)

Query: 59   PVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASP--TPKQASATTPGHESP----RET 112
            PVP   P P     P +T+  +    P   Q +      PKQ  +  P  + P    ++ 
Sbjct: 652  PVPS-SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710

Query: 113  RAQGPAGQEADGPRRTLQVDSRTQRSG-RSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCP 171
               G    +A  P    + DS ++ +  + PSV  ++   P +     Q   +  +T   
Sbjct: 711  TLHGSPSAKAKQPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT--D 765

Query: 172  ICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMT 231
            +  +S  T+ P  P+    +Q   K        P       K         ++    D  
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKT------TPPLKTDSAKPSQSFPPTGEKVSPFDSK 819

Query: 232  TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
              PR  S  ++ S    P  S             S+G     P  ++ E  +A +   P 
Sbjct: 820  AIPRPASDSKIIS---HPGPS-----------SESKGQKQVDPVQKKEEPKKAQTKMSPK 865

Query: 292  QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQT--------Q 343
              A P   G  +P  P+PT   T  P P     P + +      LG+            Q
Sbjct: 866  PDAKPMPKGSPTPPGPRPTAGQTV-PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924

Query: 344  EGLTGKLFGLGASLLTQASTLMSV--QPEADTQGQP-APSKGTPKIVFNDASKEAGPKPL 400
            E +TGKLFG GAS+ +QAS L+S   QP   +Q  P AP K  P       + +  PK  
Sbjct: 925  ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA-PSQPPTSQGPPKST 983

Query: 401  GSGPGPGPA-----------PGA-KTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
            G  P P PA           P A K EP A   P        K                 
Sbjct: 984  GQAP-PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042

Query: 449  SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508
            +    K +  PK  + CPLC+ ELN+GSK P N+NTCT C+ QVCNLCGFNPTPHL E  
Sbjct: 1043 AVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 509  EWLCLNCQTKRLLEGSLGE--------------PTPLPPPTSQQ---------------- 538
            EWLCLNCQT+R + G LG+              P P+P  +S Q                
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162

Query: 539  -----------------------PPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKAS-- 573
                                   PP+    +    S L++     L Q   PLP +    
Sbjct: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLI 1221

Query: 574  ------------PLSTKASPLPS--KASPQAKPLRASEPSK------------------T 601
                        PL  +  P P   K  P+AK     E                      
Sbjct: 1222 PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVA 1281

Query: 602  PSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEP-ATPVVKAVPEAPKGGE 660
            P +VQE K +  TK E +P   P++ P       K+   + +P  T     V    +  E
Sbjct: 1282 PKTVQEGK-QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340

Query: 661  AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQL------DSAGVT 714
             ED      S    +SPQ LSDTGYSSDGISSS  EI  ++  + + +      DS    
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQE 1400

Query: 715  GPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRP------HSLSITP 768
               P SPS++ K+ S++  +L+AQ    ++      +   E   ++P       SLS T 
Sbjct: 1401 SS-PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459

Query: 769  EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSD-----DFGSQLR-----HDYVEDS 818
            E   S+EE+++  EE +D+    ++  QQD   S D     +F   +      +D VE+S
Sbjct: 1460 EITISEEEIKESQEERKDTF---KKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES 1516

Query: 819  SEGGLSPLPPQPPARAAELT---------------DEDFMRRQILEMSAEED-NLEEDDT 862
            SE   SP+P +    +   +               +EDF+R+QI+EMSA+ED +  EDD 
Sbjct: 1517 SESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDE 1576

Query: 863  ATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGS-----AEA 917
                +      + +   +   +   +  A   RRL   ++T  +E      S      EA
Sbjct: 1577 FIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEA 1636

Query: 918  TDGSGTLQ-----------------GGLRRFKTIELNSTGSYGHELDLGQGPDPS-LDRE 959
             D S  L+                 GGLRRFKTIELNST +  +  +  Q       D E
Sbjct: 1637 FDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE 1696

Query: 960  PELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEA 1019
            PELEMESLT SPEDRSRGE SS+L AS  S+T GTSPTS+SSL+EDSDSSPS ++   E+
Sbjct: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS--SFTPGTSPTSVSSLDEDSDSSPSHKKG--ES 1752

Query: 1020 KQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
            KQQRKARHR HGPLLPTIEDSSEEEELREEEELL+EQEK RE+EQQ+ +S+++K+++DK+
Sbjct: 1753 KQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKD 1812

Query: 1080 ELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEAL 1139
            ELRAQRRRER KTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY  SPS++S+ E  
Sbjct: 1813 ELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY--SPSIESDPEGF 1870

Query: 1140 DGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQ 1199
            +  P ++ +    Y LPT +SLYSPT+  S       S + LKSAEE YEEMM K    +
Sbjct: 1871 EISPEKIIEVQKVYKLPTAVSLYSPTDEQS-IMQKEGSQKALKSAEEMYEEMMHKTH--K 1927

Query: 1200 RQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAA---------------QPA 1244
             +   AA  R          G   +  + Y+   +  Y  +                Q  
Sbjct: 1928 YKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQK 1987

Query: 1245 AEGTPASLGAAVYEEILQ-------------TSQSIVRMRQASSRDLAFAE--------- 1282
                   L   +YE+ +Q             +  S+V      S      E         
Sbjct: 1988 GREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGT 2047

Query: 1283 ---DKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQ----------------------L 1317
                 ++E++ L+A++AY + MK+    LTPG+SPTQ                       
Sbjct: 2048 MVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLT 2107

Query: 1318 AAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE--TQDPLKLHSSPASPSSASKEIGMPFS 1375
            ++ +S ++ T S SS    IPDV++TQHF+ E    + +  ++       A + + + +S
Sbjct: 2108 SSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYS 2167

Query: 1376 QGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPT-TANYGSQTED 1434
            +    P+ +A +  P+  P    +  S   +  S SP +T  S     T   +  ++ ED
Sbjct: 2168 E----PSESATSVPPSDTP-SLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFED 2222

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSP- 1493
              +  S     G         +   +   P   RA +     S     SS  ES    P 
Sbjct: 2223 SEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPE 2282

Query: 1494 GKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQE 1553
            G +    + +       P   +      G         +  +      T   + +     
Sbjct: 2283 GPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH 2342

Query: 1554 APFMVITL------------ASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601
             P  VI L            + +   Q +      S SP  S    +P    + +++   
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--RPFFRSSSLD 2400

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTP 1661
            +S  PP PP PP  P  P      P         P    +  + + +P        P T 
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPP---------PLPPPTSPKPTILPKKKLTVASPVTT 2451

Query: 1662 GTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLV 1715
             T + D  T ++ T  +L   G+ +T +   A        P+P + S+    LV
Sbjct: 2452 ATPLFDAVTTLE-TTAVLRSNGLPVTRICTTAP------PPVPPKPSSIPSGLV 2498



 Score =  224 bits (571), Expect = 1e-57
 Identities = 296/1195 (24%), Positives = 451/1195 (37%), Gaps = 142/1195 (11%)

Query: 18   PGGAGPGPGPGPG------PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGP 71
            PG   P   PGP       PG GK P+  AG G+  A     +     +PGP   P   P
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484

Query: 72   GPGSTSRRL--DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTL 129
            GP     +     K P     +  P P+Q     P  + P  T+   P  Q+    + + 
Sbjct: 485  GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSA 541

Query: 130  QVDSRTQRSGRSPS--VSPDRGSTPTSPYSVPQIAPLPSS-----TLCPICKTSD-LTST 181
            Q  S  + S +  +  VS      P  P +V   A  P S     T+CP+C T++ L   
Sbjct: 542  QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601

Query: 182  PSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQ 241
            P + NFNTCT+C   VC+ CGFNPNPHLT+VKEWLCLNCQM+RALG D+   P S   + 
Sbjct: 602  PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661

Query: 242  LHSPALSPA-----------HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGP 290
              +P  + +            SP K    K D  ++  P  P P  +Q     + S    
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS---- 717

Query: 291  AQAAAPPEVGRVS-PQPP-QPTKPSTAEPRPPAGEAP-----AKSATAVPAGLGAT---- 339
            A+A  PPE   +S P PP +P+ PS  +  P A + P      K  T + +   AT    
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777

Query: 340  -------EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFND-A 391
                    Q +E  T         L T ++      P    +  P  SK  P+   +   
Sbjct: 778  IPSSKVQSQAEEKTT-------PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830

Query: 392  SKEAGPKPLGSGPGPGPAPGAKTEP---GARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
                GP     G         K EP     +M P      +PK G  T P       Q  
Sbjct: 831  ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTV 889

Query: 449  SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVC-NLCGFNPTPHLVEK 507
                  PK   + R      +  LN+GS + A  +  TT +  V   L GF  +      
Sbjct: 890  PTPQQSPKPQEQSR------RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS------ 937

Query: 508  TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR---ASGTSPLKQKGPQGLGQP 564
                 +  Q   L+  + G+    P P SQ  P GAP +   A    P  Q  P+  GQ 
Sbjct: 938  -----IFSQASNLI-STAGQ----PGPHSQSGP-GAPMKQAPAPSQPPTSQGPPKSTGQ- 985

Query: 565  SGPLPAKASPLSTKA-SPLPSKASP---QAKPLRASEPSKTPSSVQEKKTR--------V 612
            + P PAK+ P+  +  +P   K  P   QA  ++ +E  K P  +++ K+         +
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045

Query: 613  PTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQD 672
            PTK E  PK  PE+T     P  K+ +       P      E     +  +L G   +  
Sbjct: 1046 PTKLEKSPK--PEST----CPLCKTELNIGSKDPPNFNTCTECK--NQVCNLCGFNPTPH 1097

Query: 673  ASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
             +   + L     +   IS    +I     +++    S     P  P P+E     +++ 
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDI-----RKMPPAPSGPKASP-MPVPTESSSQKTAVP 1151

Query: 733  PLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSA--EW 790
            P ++       E          E+ K+      I P      ++ E  LE+D+ SA  E 
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211

Query: 791  RRRREQQDTAESSDDFGSQLRHDYVEDSSEGGL-SPLPPQPPARAAELTDEDFMRRQILE 849
            +   E++      +   S+ +   +E+         L P+    A E    D ++ Q+  
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQI 1271

Query: 850  MSAEEDNLEEDDTATSGR--GLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
               + +      T   G+       G   G P+  P+   +     K +     T   ++
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331

Query: 908  LLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESL 967
            + P     E  D         +      L+ TG     +    G  PSL   P  E + L
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL--IPTDEKDIL 1389

Query: 968  TGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS-----DSSPSRRQRLEEAKQQ 1022
             G  +D    E S     S+PS  +    T LS LE  +     + S  + Q  E + +Q
Sbjct: 1390 KGLKKDSFSQESS----PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ 1445

Query: 1023 RKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR 1082
             K + ++   L  T+E +  EEE++E +E    ++  ++  QQ I S+  K  ++K E  
Sbjct: 1446 PKDQEKTQS-LSETLEITISEEEIKESQE--ERKDTFKKDSQQDIPSS--KDHKEKSEFV 1500

Query: 1083 AQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAE 1137
                  R        S   + SP  + ++   +     SS  EY    S  S  E
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGS---SSSDEYKQEDSQGSGEE 1552



 Score =  171 bits (433), Expect = 1e-41
 Identities = 173/628 (27%), Positives = 235/628 (37%), Gaps = 116/628 (18%)

Query: 242 LHSPALSPAH--SPAKQPLGKPDQERSR-GPGGP-------------QPG---------- 275
           L SP+  P    +P K P  +P  E+S+ GP  P             QPG          
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 276 ---------------SRQAETARATS-VPGPAQAAAPPEVGRVSPQPPQPTKPSTAE--- 316
                          ++Q  + + +S  PGP   A PP VG+   Q P P KP T +   
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417

Query: 317 PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASL-LTQASTLMSVQPEADTQG 375
           P+P A + P   + A   G   T   Q G  GK+    A    T A      +P +   G
Sbjct: 418 PKPLA-QQPGLQSPAKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475

Query: 376 QPAPSKGTPKIVFNDASKEAGPKPLGSGPG--------PGPAPGAKTEPGARMGPGSGPG 427
              P    P        +    KP    PG        PGPA  +  +PG+   P   PG
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535

Query: 428 ALPKTGGTTSPKHGRAEHQ----------------AASKAAAKPKTMPKERAICPLCQ-A 470
           +   +    SP    A+                    S +A +P +    + ICPLC   
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595

Query: 471 ELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP 530
           EL +     AN+NTCT C+  VC+LCGFNP PHL E  EWLCLNCQ KR L G L     
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655

Query: 531 LPPPTSQQPPVGAPHRAS-------GTSPLKQKGP-QGLG---QPSGPLPAKASPLSTKA 579
            P P  +  PV      S        TSP K   P Q L    +P  P P    P    +
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715

Query: 580 SPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGV 639
               +K  P+A  L    P K P SV  ++ + P  A+  PK P    PT  T  V S  
Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEP-SVPSEQDKAPV-ADDKPKQPKMVKPT--TDLVSSSS 771

Query: 640 RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTG-----YSSDGISSSQ 694
              +P       +P +    +AE+    P   D+++  QS   TG     + S  I    
Sbjct: 772 ATTKP------DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825

Query: 695 SEITGVVQQEVEQLDSAGVTGPHPPSPS----EIHKVGSSMRPLLQAQGLAPSERSKPLS 750
           S             DS  ++ P P S S    ++  V     P      ++P   +KP+ 
Sbjct: 826 S-------------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872

Query: 751 SGTGEEQKQRPHSLSITPEAFDSDEELE 778
            G+      RP +    P    S +  E
Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQE 900



 Score =  110 bits (274), Expect = 4e-23
 Identities = 189/740 (25%), Positives = 286/740 (38%), Gaps = 151/740 (20%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P  P   P     P     PTS   +   ++P  ++T      T  PL    +    ++ 
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPT---ILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTA 1426
             +  G+P ++   T A   V P P+ +P G +    P   E S  P +        PTT 
Sbjct: 2468 LRSNGLPVTR-ICTTAPPPVPPKPSSIPSGLVFTHRP---EPSKPPIAPKPVIPQLPTTT 2523

Query: 1427 NYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPS 1486
                +  D+   P+GL+           SA   +   P P+           PLSP S  
Sbjct: 2524 Q---KPTDIHPKPTGLSLTSSMTLNLVTSA---DYKLPSPTS----------PLSPHSNK 2567

Query: 1487 ESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
             SP FS        T  +   T        +P  PG PT S      T  P    +  LV
Sbjct: 2568 SSPRFSKS-----LTETYVVIT--------LPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614

Query: 1547 WQESSQEAPFMVITLASD-----ASSQTRMVHASAST---SPLCSPTETQ--PTTHGYSQ 1596
                S E  F V+   +      +S QT  +  +  T   +P+ +P+  Q  PT+     
Sbjct: 2615 ----SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFL 2670

Query: 1597 TTPPSVSQLPPEPPGPP--GFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRV 1654
            TT  S +++       P  G   +       PLAL        +NI L +          
Sbjct: 2671 TTEVSKTEVSATRSTAPSVGLSSISITIPPEPLAL--------DNIHLEK------PQYK 2716

Query: 1655 EPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPL 1714
            E G       V+DLRT  K   +  TD+ +DL++  ++ ++  +  + + G+Q +AVQP 
Sbjct: 2717 EDGKLQLVGDVIDLRTVPK-VEVKTTDKCIDLSASTMDVKRQ-ITANEVYGKQISAVQPS 2774

Query: 1715 VINLNAQEH----TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVC 1770
            +INL+          LAT T   +T  +S       + +V  +   +         +P+ 
Sbjct: 2775 IINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMT---------TPLQ 2825

Query: 1771 LAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLP-NQVAPLARRDVLIT-QMGT-AQSI 1827
            L   K  E      PYR                +P +QV P+AR +  I   +GT A ++
Sbjct: 2826 LTTSKHAE-----PPYR----------------IPSDQVFPIAREEAPINLSLGTPAHAV 2864

Query: 1828 GL---KPGPVPEPGAEPHRATPAELRSHALPG------ARKPHTVVVQMGEGTAGTVTTL 1878
             L   KP  VP  G   +  T + +      G        K H  VV M E T+  +T +
Sbjct: 2865 TLAITKPVTVPPVGV-TNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKI 2923

Query: 1879 LPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSS 1938
            + +E    +DLT  R   +  CCD+VYKLPFG SCT    PA ++PE             
Sbjct: 2924 IEDEK--PVDLTAGR---RAVCCDVVYKLPFGRSCTAQ-QPATTLPEDR----------- 2966

Query: 1939 SPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHA 1998
               +G RD        Y+         ++   PY     G +  SMSDTNLAEAG  ++ 
Sbjct: 2967 ---FGYRDDH------YQ---------YDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYK 3008

Query: 1999 QRIGQLFQGPGRDSAMDLSS 2018
             +        G D+A+DL+S
Sbjct: 3009 SK-NAFDYSEGTDTAVDLTS 3027



 Score = 79.7 bits (195), Expect = 5e-14
 Identities = 142/656 (21%), Positives = 213/656 (32%), Gaps = 100/656 (15%)

Query: 1   MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPP--SAPAG-GGQLPAAGAARSTAV 57
           MGNE SLEG      LP G A      G   GAG P   + PAG    L          +
Sbjct: 1   MGNEASLEGEG----LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI 56

Query: 58  PPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP 117
             V     G   G  P           P   +  +    ++  ++ P  +S R      P
Sbjct: 57  AAVMSRAQGLPKGSVP-----------PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP 105

Query: 118 AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSD 177
           A       R T    S  +  GRSPS    + S   +       + +    L  +   S 
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSA 165

Query: 178 LTS-----------TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRAL 226
           ++S           + S+ +    T+    V  + G         +++        Q+  
Sbjct: 166 VSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGP 225

Query: 227 GMD---MTTAPRSKSQQQLHSPALSPAHS--PAKQPLGKPDQERSRGP---GGPQPGSRQ 278
           G D       P+S S QQ       P  +  P + P   P  + ++ P      +P ++Q
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285

Query: 279 AETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGA 338
           A+  R  SV     + + P + + +P  P   +P   + +P   + PA+     P+GL  
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ-----PSGLTK 340

Query: 339 TEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
               Q G          +    A  L   +P A   G   PS           S++ GPK
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS-----------SEQPGPK 389

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
            L   PG G  P  +       GP   P    +  GT  P   +   Q+ +KA    KT 
Sbjct: 390 ALAQPPGVGKTPAQQP------GPAKPP---TQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
            ++     +   +   G  S                     P   L              
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPT-------------KPPSQL-------------- 473

Query: 519 RLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS-PLKQKGPQGLGQPSGPLPAKASPLST 577
                    P P  PP  Q  P   P +  G++ P  Q+       P  P PAK SP   
Sbjct: 474 ---------PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524

Query: 578 KASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
            ++  PS+    AKP  A +PS    S Q+    V       P  PP  +P+   P
Sbjct: 525 GSTKPPSQQPGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 70.5 bits (171), Expect = 3e-11
 Identities = 147/676 (21%), Positives = 235/676 (34%), Gaps = 117/676 (17%)

Query: 956  LDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQR 1015
            +  E  LE E L   PE    G  ++       S     S T++ +  E   S  S  +R
Sbjct: 1    MGNEASLEGEGL---PE----GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEER 53

Query: 1016 LEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTR 1075
             + A    +A+    G + P   +S      +E +     ++  R  +  R         
Sbjct: 54   RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKS 113

Query: 1076 RDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135
            R  +  R++++       PS +S  E  S T+       ++E H+SS       P   SE
Sbjct: 114  RTTDTFRSEQKLPGRS--PSTISLKESKSRTD-------LKEEHKSSMM-----PGFLSE 159

Query: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKA 1195
              AL    S + K             ++P +  S S             E + EE  +K 
Sbjct: 160  VNALSAVSSVVNK-------------FNPFDLISDS-------------EASQEETTKKQ 193

Query: 1196 ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE-------YQDTTDREYGQAAQPAAEGT 1248
            +++Q++QG+  G   P   P Q   P+ +   +        QD T +          +  
Sbjct: 194  KVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250

Query: 1249 PASLGAAVY--EEILQTSQSIVRMRQASSR------DLAFAEDKKKE-----KQFLNAES 1295
            P   G  +    +  QT  + + +++ +SR      D+   E  K       K  +   +
Sbjct: 251  PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 1296 AYMDPMKQNG------GPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE 1349
                P +Q G      GP  P   P+ L  P++           G V P V+        
Sbjct: 311  PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA--------QQPGTVKPPVQ-----PPG 357

Query: 1350 TQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERS 1409
            T  P      PA P +       P S+ PG P   A  P     P     PA P  +++ 
Sbjct: 358  TTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQPPGVGKTPAQQPGPAKPP-TQQV 415

Query: 1410 PSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
             +P   A   G        G     + Q   G   A +A   K  +++   G T  PS+ 
Sbjct: 416  GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK--TSAQQTGPTKPPSQL 473

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                  + PP     P++ P   PG   P +    ST+ P        P+ PG   PSP 
Sbjct: 474  PG---PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP--------PQQPGPAKPSPQ 522

Query: 1530 VAQGTQTP-HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPL----CSP 1584
                T+ P  +P + +   Q+ S   P         A   T+ V  + S  PL     SP
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSPAKP--------SAQQSTKPVSQTGSGKPLQPPTVSP 574

Query: 1585 TETQPTTHGYSQTTPP 1600
            +  QP + G  +T  P
Sbjct: 575  SAKQPPSQGLPKTICP 590



 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 248/1193 (20%), Positives = 383/1193 (32%), Gaps = 269/1193 (22%)

Query: 2751 TPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTS 2810
            +P  +   E K    L+  +++ + P  LS++       +   + S V+  +P  L+  S
Sbjct: 129  SPSTISLKESKSRTDLKEEHKSSMMPGFLSEV------NALSAVSSVVNKFNPFDLISDS 182

Query: 2811 FASSERLNKAHVSPQKHFTADSAL----RQQTLPRPMKTLQRSLSDPKPLSPTAEESAKE 2866
             AS E   K     QK       +     QQ  P+P+   Q    DP             
Sbjct: 183  EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL------------ 230

Query: 2867 RFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRG 2926
                   Q G    +S+  P     K+K    S PP        G   P           
Sbjct: 231  ------QQDGTPKSISSQQPE----KIK----SQPP--------GTGKP----------- 257

Query: 2927 LTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQR 2986
            + GPT  P T  + L         ++ ++++ + KQA++   E  +   L       +  
Sbjct: 258  IQGPTQTPQTDHAKLP--------LQRDASRPQTKQADIVRGES-VKPSLP------SPS 302

Query: 2987 KESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQF-------VDFPATA 3039
            K  + +   G+  PP +  G  +     ++    +  G T P  Q        V  P T 
Sbjct: 303  KPPIQQPTPGK--PPAQQPGHEKSQPGPAK-PPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 3040 AAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG--PSTYPAPAFPPG 3097
              PA P GP        +PPA Q  +      Q G  A   P   G  P+  P PA PP 
Sbjct: 360  KPPAQPLGPA-------KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP- 411

Query: 3098 ASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKV 3157
                 + G P   A +P      + P PT      P P    A    P +TS        
Sbjct: 412  ---TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468

Query: 3158 PTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKV-PEVPRAGDRGSVSQSPAPTYPS 3216
            P +   +  P  P    P      GPA     + G   P   + G      Q P P  PS
Sbjct: 469  PPSQ--LPGPAKPPPQQP------GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520

Query: 3217 DSHYTSLE--QNVPRNYVMIDDISELTKDST--STAPDSQRL--EPLGPGSSGRPGKEPG 3270
                 S +     P +           K S   ST P SQ    +PL P +     K+P 
Sbjct: 521  PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580

Query: 3271 EPGVLDGPTLPCCYARG-----EEESEEDS-------------YDP-------------- 3298
              G L     P C          E++  ++             ++P              
Sbjct: 581  SQG-LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639

Query: 3299 ----RGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAIS 3354
                R  GG L  + S+ +P        +     + V K  P P     P K  AP    
Sbjct: 640  CQMKRALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDL 694

Query: 3355 SKRSKHRKQG--MEQKISKFSPIEEAKDV-ESDLASYPPPAVSSSLVSRGRK--FQDEIT 3409
            SK  + +K    ++Q     SP  +AK   E+D  S P P    S+ S   K    D+  
Sbjct: 695  SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754

Query: 3410 YGLK--KNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYE 3467
               K  K   +       +++  +   ++   +     P   +     S  F   G    
Sbjct: 755  KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG---- 810

Query: 3468 REREAVERLQ-KAGPKPSSLSMAHSRVRPPMRSQASEEESPV---------------SPL 3511
               E V     KA P+P+S S   S   P   S+  ++  PV                P 
Sbjct: 811  ---EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 3512 GRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDS 3571
             +P P G P PPG    P+  +  ++P  Q+  K   ++  +    G I D         
Sbjct: 868  AKPMPKGSPTPPG----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK------ 917

Query: 3572 EAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPH 3631
                  Q  T     P++  + +    G    S +S     A                PH
Sbjct: 918  -----SQPTT-----PQETVTGKLFGFGASIFSQASNLISTAGQP------------GPH 955

Query: 3632 DEGGPG---RHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA 3688
             + GPG   + A A        G    + TG+ P                      P+ A
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQG--PPKSTGQAP----------------------PAPA 991

Query: 3689 PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK---AEPQAQP 3745
             ++P K +   P++ +    +  +         KK        P    SK   AEPQ   
Sbjct: 992  KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK-------PPPIKDSKSLTAEPQKAV 1044

Query: 3746 QLQGRQAAPGPQQSQSPSSRQIPSGAASRQP-------QTQQQQQGLGLQPPQQALTQAR 3798
                 + +P P+ +      ++  G  S+ P       + + Q   L    P   LT+ +
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIG--SKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 3799 ----LQQQSQPTTRGS-------APAASQPAGKPQPGPSTATGPQPAGPPRAE 3840
                L  Q+Q    G         PA S P   P P P+ ++  + A PP+ +
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155



 Score = 59.3 bits (142), Expect = 7e-08
 Identities = 77/279 (27%), Positives = 110/279 (39%), Gaps = 42/279 (15%)

Query: 3655 GRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYP--------SSAEYS 3706
            G+   ++PG   ++P         A+P +QPS     P   QPG          ++   +
Sbjct: 312  GKPPAQQPGHEKSQPGP-------AKPPAQPSGL-TKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 3707 QPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQ--SQSPSS 3764
            QP   +      + S+K S +   GP AL         P  Q   A P  QQ  +  P +
Sbjct: 364  QPLGPAKPPAQQTGSEKPSSE-QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 3765 RQIPSGAASRQP---QTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSA-PAASQPAGK 3820
            +Q    + ++ P   +T  QQ G G  P QQA       QQ+ PT   S  P  ++P  +
Sbjct: 423  QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
             QPGP+     QP             G+AK P Q       P   PGPA  K   +  G+
Sbjct: 483  -QPGPAKPPPQQP-------------GSAKPPSQQPGSTKPPPQQPGPA--KPSPQQPGS 526

Query: 3881 PGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFG 3919
               P+ QPG+   S      P  A   A + T+ VS  G
Sbjct: 527  TKPPSQQPGSAKPSAQQ---PSPAKPSAQQSTKPVSQTG 562



 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 96/442 (21%), Positives = 152/442 (34%), Gaps = 70/442 (15%)

Query: 3477 QKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHS 3536
            +K+ P P+      S +  P+  Q    + PV P G  +P   PL P      Q  S   
Sbjct: 322  EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 3537 MPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFR 3596
              +     + GP+A A     G          + ++     +  T     P+        
Sbjct: 382  SSE-----QPGPKALAQPPGVGK---------TPAQQPGPAKPPTQQVGTPKPLAQQP-- 425

Query: 3597 HHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSG- 3655
                  + S ++  GP +       + P  G  P  + GPG+ ++ +        +  G 
Sbjct: 426  -----GLQSPAKAPGPTKTPV----QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 3656 -RHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSA 3714
             +   ++PG   AKP  +  G  +  P  QP S    P++  P  PS     QP      
Sbjct: 477  AKPPPQQPG--PAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPSP---QQPGSTKPP 530

Query: 3715 YHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASR 3774
                  +K  ++Q    P+  +  A+   +P  Q     P    + SPS++Q PS    +
Sbjct: 531  SQQPGSAKPSAQQ----PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586

Query: 3775 QPQTQQQQQGLGLQPPQQA-----------------------LTQAR----LQQQSQPTT 3807
                      L L  P++A                       LT+ +    L  Q +   
Sbjct: 587  TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646

Query: 3808 RGS-APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP 3866
             G  AP  S P  K +  P T T       P+ +QT+  K  A      +AP+    P  
Sbjct: 647  GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE----PKK 702

Query: 3867 GPAGVKAGARPGGTPGAPAGQP 3888
             P  VK      G+P A A QP
Sbjct: 703  PPPLVKQPTL-HGSPSAKAKQP 723



 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 107/482 (22%), Positives = 165/482 (34%), Gaps = 60/482 (12%)

Query: 3438 GGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPM 3497
            GG+S + +PS  +       D S   +   R+  AV    +  PK  S+  A +      
Sbjct: 24   GGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK-GSVPPAAAESPSMH 82

Query: 3498 RSQASEEESPVSPLGRPRPAGGPLPPG---GDTCPQFCSSHSMPDVQEHV---------K 3545
            R Q  +   P    GRP   G P  PG     T   F S   +P                
Sbjct: 83   RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRT 142

Query: 3546 DGPRAHAYKREEGYILD--------------DSHCVVSDSEAYHLGQEETDWFDKPRDAR 3591
            D    H      G++ +              +   ++SDSEA    QEET    K +  +
Sbjct: 143  DLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA---SQEETT--KKQKVVQ 197

Query: 3592 SDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHG 3651
             ++ +  G        Q   P         +P ++      +G P   +S +  +     
Sbjct: 198  KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQ------DGTPKSISSQQPEKIKSQP 251

Query: 3652 RHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRA 3711
              +G+   + P +     HA+   + +A   S+P +  A   +G+   PS    S+P   
Sbjct: 252  PGTGKPI-QGPTQTPQTDHAKLPLQRDA---SRPQTKQADIVRGESVKPSLPSPSKPPIQ 307

Query: 3712 SSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGA 3771
                      + G  ++  GPA      +P AQP    +  A  P   + P     P G 
Sbjct: 308  QPTPGKPPAQQPGHEKSQPGPA------KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGT 358

Query: 3772 ASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGP 3831
                 +   Q  G    P QQ  ++    +Q  P      P   +   + QPGP+     
Sbjct: 359  T----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQ 413

Query: 3832 QPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV----KAGARPGGTPGAPAGQ 3887
            Q   P    Q  G +  AKAP   + P  QP PG  PA      K  A+  G    P+  
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 3888 PG 3889
            PG
Sbjct: 474  PG 475



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 146/706 (20%), Positives = 236/706 (33%), Gaps = 142/706 (20%)

Query: 290 PAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPA--GLGATEQTQEGLT 347
           P Q+  PP+ GR  P  P  +K  T +      + P +S + +        T+  +E  +
Sbjct: 93  PKQSGRPPDPGR--PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150

Query: 348 GKLFGLGASLLTQASTLMSVQPE-------ADTQGQPAPSKGTPKIVFNDASKEAG--PK 398
             + G   S +   S + SV  +       +D++     +    K+V  +  K  G    
Sbjct: 151 SMMPGF-LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGP---GALPKTGGTTSPKHGRAEHQAASKAAAKP 455
           PL   P P P P        + GPG  P      PK+  +  P+  +++     K    P
Sbjct: 210 PLQQQP-PKPIP-------KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261

Query: 456 KTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC 515
              P+               +K P   +       Q   + G +  P L   ++      
Sbjct: 262 TQTPQTDH------------AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK------ 303

Query: 516 QTKRLLEGSLGEPTPLPPPTSQQPPVGAP-HRASGTSPLKQKG-PQGLGQPSGPLPAKAS 573
                         P+  PT  +PP   P H  S   P K    P GL +P    P    
Sbjct: 304 -------------PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350

Query: 574 PLSTKASPLPSKASPQAKPLRASEP------SKTPSSVQEKKT---------RVPTKAEP 618
           P      P P    P A+PL  ++P      S+ PSS Q             + P +   
Sbjct: 351 P---PVQP-PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 619 MPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ 678
             KPP +   TP     + G++    A    K   + P         GK  +Q A     
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG-------PGKIPAQQAGPGKT 459

Query: 679 SLSDTGYSS-----DGISSSQSEITGVVQQEVEQLDSA-------GVTGPHPPSPSEI-- 724
           S   TG +       G +    +  G  +   +Q  SA       G T P P  P     
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519

Query: 725 --HKVGSSMRPLLQAQGLAPS------------ERSKPLSSGTGEEQKQRPHSLSIT--- 767
              + GS+  P  Q     PS            + +KP+S  TG  +  +P ++S +   
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-TGSGKPLQPPTVSPSAKQ 578

Query: 768 ------PEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVED---- 817
                 P+         ++L    + A +    E Q T  S   F        V++    
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638

Query: 818 ------SSEGGLSPLP--PQPPARAAELTDEDFMRR---QILEMSAEEDNLEEDDTATSG 866
                 +  G L+P+P  PQP  + A +T    + +   Q  + S ++D   + D + + 
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698

Query: 867 R-----GLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
                  L K  T  G P  + +   E  +L K   P   +   E+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 33/247 (13%)

Query: 3670 HARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYS--------QPSRASSAYHHASDS 3721
            H     + +  P +   S PA PK  +P  PS  + +        QP          S S
Sbjct: 713  HGSPSAKAKQPPEADSLSKPAPPK--EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 3722 KKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ 3781
               + +     + +QS+AE +  P L+   A P   QS  P+  ++    +   P+    
Sbjct: 771  S-ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS--QSFPPTGEKVSPFDSKAIPRPASD 827

Query: 3782 QQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG--PSTATGPQPAGP-PR 3838
             + +    P    ++++ Q+Q  P  +   P  +Q    P+P   P     P P GP P 
Sbjct: 828  SKIISHPGPS---SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884

Query: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSK 3898
            A QT         PQQ   PQ Q          +     G    AP  QP    E+V  K
Sbjct: 885  AGQT------VPTPQQSPKPQEQSR--------RFSLNLGSITDAPKSQPTTPQETVTGK 930

Query: 3899 ILPGGAA 3905
            +   GA+
Sbjct: 931  LFGFGAS 937



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 171/856 (19%), Positives = 276/856 (32%), Gaps = 133/856 (15%)

Query: 3044 TPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQA----PTYPGPSTYPAPAFPPGAS 3099
            +PS P   Q    +PPA Q       P     PA  +    P    P T   P  PPG +
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 3100 YP-AEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVP 3158
             P A+P  P +   + TG     +  P  ++   P P   + P Q+P          K P
Sbjct: 360  KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGPA-------KPP 411

Query: 3159 TNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQG--KVPEVPRAGDRGSVSQSPAPTYPS 3216
            T       P+       S     GP  +   + G  K+P   +AG   + +Q   PT P 
Sbjct: 412  TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPP 470

Query: 3217 DSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGE---PG 3273
             S      +  P+                   P   +  P  PGS+  P ++PG    P 
Sbjct: 471  -SQLPGPAKPPPQQ------------------PGPAKPPPQQPGSAKPPSQQPGSTKPPP 511

Query: 3274 VLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEK 3333
               GP  P     G  +       P  + G  +       PA       S  +    V +
Sbjct: 512  QQPGPAKPSPQQPGSTKP------PSQQPGSAKPSAQQPSPAKP-----SAQQSTKPVSQ 560

Query: 3334 YGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAV 3393
             G G        K L P  +S    +   QG+ + I       E       L   P  A 
Sbjct: 561  TGSG--------KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKAN 606

Query: 3394 SSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEK 3453
             ++             +    ++ E +++  ++     +  R  GG       S     K
Sbjct: 607  FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC----QMKRALGGDLAPVPSSPQPKLK 662

Query: 3454 LSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGR 3513
             +    +        + +     + A PK         +  PP+  Q +   SP +   +
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 3514 PRPAGG---PLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCV--- 3567
            P  A     P PP   + P      S  D      D P+     +    ++  S      
Sbjct: 723  PPEADSLSKPAPPKEPSVP------SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 3568 -VSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEE 3626
             +  S+     +E+T    K   A+  +     G  VS    K  P   S        + 
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS--------DS 828

Query: 3627 GLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRR----AAKPHARDLGRHEARPH 3682
             +  H    PG  + +K  +  D  +       EEP +     + KP A+ + +    P 
Sbjct: 829  KIISH----PGPSSESKGQKQVDPVQKK-----EEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 3683 S-QPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGS----RQAHSGP----- 3732
              +P++   +P   Q   P      Q  R S      +D+ K      ++  +G      
Sbjct: 880  GPRPTAGQTVPTPQQSPKPQE----QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFG 935

Query: 3733 AALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQ 3792
            A++ S+A       L      PGP     P +    + A S+ P +Q   +  G  PP  
Sbjct: 936  ASIFSQAS-----NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990

Query: 3793 ALTQARLQQQSQPTTRGS-APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA 3851
            A        +S P  + + APAA +   K +  P+         PP  +    SK     
Sbjct: 991  A--------KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKD---SKSLTAE 1039

Query: 3852 PQQGRAP-QAQPAPGP 3866
            PQ+   P + + +P P
Sbjct: 1040 PQKAVLPTKLEKSPKP 1055



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 154/705 (21%), Positives = 241/705 (34%), Gaps = 133/705 (18%)

Query: 1351 QDPLKLHSSPASPSSASKE--------IGMPFSQGPGTPATTAVAPCP------------ 1390
            +DPL+   +P S SS   E         G P  QGP     T  A  P            
Sbjct: 227  RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQ 285

Query: 1391 AGLPRGY-MTPASPAGSE---RSPSPSST-AHSYGHSPTTANYGSQTEDLPQAPSGLAAA 1445
            A + RG  + P+ P+ S+   + P+P    A   GH  +           P  PSGL   
Sbjct: 286  ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----PAQPSGLT-- 339

Query: 1446 GRAAREKPLSASDGEGGTP-QPSRAYSYFASSSPPLSPSSPSESPTFSPG-------KMG 1497
                  KPL+   G    P QP        ++ PP  P  P++ P    G       + G
Sbjct: 340  ------KPLAQQPGTVKPPVQPP------GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387

Query: 1498 PRATAEFST--QTPSPAPASDMPRSPGAPTPSPMVAQ-GTQTPHRPSTPRL--VWQESSQ 1552
            P+A A+     +TP+  P    P +    TP P+  Q G Q+P +   P    V Q    
Sbjct: 388  PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
            + P         ++ QT          P   P++             P  ++ PP+ PGP
Sbjct: 448  KIPAQQAGPGKTSAQQT---------GPTKPPSQL------------PGPAKPPPQQPGP 486

Query: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRIS-SVPGTSRVEPGPRTPGTAVVDLR-- 1669
               P      A  P    G    P +     + S   PG+++  P  + PG+A    +  
Sbjct: 487  AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK--PPSQQPGSAKPSAQQP 544

Query: 1670 TAVKPT------PIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH 1723
            +  KP+      P+  T  G  L    V           +P           + L+  E 
Sbjct: 545  SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604

Query: 1724 TFLATATTVSITMAS------SVFMAQQKQPVVYGDPYQSRL--DFGQGGGSPVCLAQVK 1775
                T T    T+ S      +  + + K+ +      +  L  D      SP    ++K
Sbjct: 605  ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLK 662

Query: 1776 QVEQAVQTAPYRSGPRGR---PREAKFARYNL-----PNQVAPLARRDVL-------ITQ 1820
                   +A  +S P+ +   P++    + +L     P +  PL ++  L         Q
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 1821 MGTAQSIGLKPGPVPEPG--AEPHRATPAELRSHALPGARKPHTVVVQMGEGT------A 1872
               A S+  KP P  EP   +E  +A  A+ +    P   KP T +V     T      +
Sbjct: 723  PPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQ-PKMVKPTTDLVSSSSATTKPDIPS 780

Query: 1873 GTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAA 1932
              V +   E+    L     +P             PF S       P P+   K ++   
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS-PFDSKAI----PRPASDSKIISHPG 835

Query: 1933 PPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            P  +S        DP   +    +AQ  + P P  + +P P+G P
Sbjct: 836  PSSESKG--QKQVDPVQKKEEPKKAQTKMSPKP--DAKPMPKGSP 876



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 55/199 (27%), Positives = 75/199 (37%), Gaps = 15/199 (7%)

Query: 3694 KGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAA 3753
            K    +P + E   P  + +    ASDSK  S   H GP++ +SK + Q  P +Q ++  
Sbjct: 801  KPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS---HPGPSS-ESKGQKQVDP-VQKKEEP 855

Query: 3754 PGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPA 3813
               Q   SP     P    S  P   +   G  +  PQQ+    + Q+QS+  +      
Sbjct: 856  KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSI 912

Query: 3814 ASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAP----QQGR-APQAQ-PAPGP 3866
               P  +P     T TG     G     Q +    TA  P    Q G  AP  Q PAP  
Sbjct: 913  TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972

Query: 3867 GPAGVKAGARPGGTPGAPA 3885
             P         G  P APA
Sbjct: 973  PPTSQGPPKSTGQAPPAPA 991



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/219 (25%), Positives = 75/219 (34%), Gaps = 53/219 (24%)

Query: 521  LEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKAS 580
            L+ S   P P PPP    PP   P                   P  PLP   SP   K +
Sbjct: 2399 LDISAQPPPPPPPPPPPPPPPPPP-------------------PPPPLPPPTSP---KPT 2436

Query: 581  PLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPK----PPPETTPTPATPKVK 636
             LP K    A P+  + P     +  E    + +   P+ +     PP   P P++  + 
Sbjct: 2437 ILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS--IP 2494

Query: 637  SGV---RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSS 693
            SG+    R EP+ P     P AP          KP       + Q  +D      G+S +
Sbjct: 2495 SGLVFTHRPEPSKP-----PIAP----------KPVIPQLPTTTQKPTDIHPKPTGLSLT 2539

Query: 694  QSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
             S    +V        SA    P P SP   H   SS R
Sbjct: 2540 SSMTLNLV-------TSADYKLPSPTSPLSPHSNKSSPR 2571



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/242 (24%), Positives = 83/242 (34%), Gaps = 36/242 (14%)

Query: 1452 KPLSASDGEG-------GTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEF 1504
            KP+    G G       GTP+   +       S P     P + PT +P     +   + 
Sbjct: 217  KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 1505 STQTPSPAPASDMPRS----PGAPTPS-PMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
                P    A D+ R     P  P+PS P + Q   TP +P   +    E SQ  P    
Sbjct: 277  DASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQ--PTPGKPPAQQ-PGHEKSQPGP---- 328

Query: 1560 TLASDASSQTRMVHASASTSPLCS-PTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
                           S  T PL   P   +P       T PP+    P +PP        
Sbjct: 329  --------AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 1619 PSAGADGPLALY---GWGALPAENISLCRISS----VPGTSRVEPGPRTPGTAVVDLRTA 1671
            PS+   GP AL    G G  PA+     +  +     P     +PG ++P  A    +T 
Sbjct: 381  PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 1672 VK 1673
            V+
Sbjct: 441  VQ 442



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 41/161 (25%), Positives = 52/161 (32%), Gaps = 32/161 (19%)

Query: 2201 PIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYR 2260
            P   T P+  QP +V  P+   G  +P                     P  PLGP     
Sbjct: 335  PSGLTKPLAQQPGTVKPPVQPPGTTKP---------------------PAQPLGPA---- 369

Query: 2261 YPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIK 2320
               P      S  P +E P   G  A A+ PG G    P    G A+       TP  + 
Sbjct: 370  --KPPAQQTGSEKPSSEQP---GPKALAQPPGVG--KTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 2321 EAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQ 2361
            +  G  +PA   G        PG G     + G  K  A Q
Sbjct: 423  QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 61/265 (23%), Positives = 91/265 (34%), Gaps = 70/265 (26%)

Query: 528  PTPLPPPTSQQPPVGAPHRASGTSPLKQKGP--------------QGLGQP------SGP 567
            P PLPPPTS +P +    + +  SP+    P              +  G P      + P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483

Query: 568  LPAKASPLSTKAS------PLPSKASPQAKPLRASEPSKT--PSSVQEKKT--------- 610
             P    P S  +       P PSK     KP+    P+ T  P+ +  K T         
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543

Query: 611  -RVPTKAE---PMPKPPPETTPTPATPKVKSGVRR--------AEPATPVVKAVPEA--- 655
              + T A+   P P  P       ++P+    +          +EP TP   +  +A   
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603

Query: 656  -PKGGEAEDLVG-KPYSQ-----DASRSPQSLSDTGYSSDGI-----------SSSQSEI 697
             P G  ++DLV  +P         A   P S   T Y S  +           SS Q+  
Sbjct: 2604 WPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAP 2663

Query: 698  TGVVQQEVEQLDSAGVTGPHPPSPS 722
            T V Q    ++    V+     +PS
Sbjct: 2664 TSVTQFLTTEVSKTEVSATRSTAPS 2688



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 1490 TFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTP------SPMVAQGT--QTPHRPS 1541
            T+  G +G +  A+  TQ+P    A+  P+    PTP      S + A  T    P  P 
Sbjct: 3559 TYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPK 3618

Query: 1542 TPRLVWQESSQEAPFMVITLA--------SDASSQTRMVHASASTSPLCSPTETQPTTHG 1593
            +P++++   S  +P   +  A         D  S  +++H   +  P  SP   +     
Sbjct: 3619 SPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRS 3678

Query: 1594 YSQTTPPS 1601
             S   P S
Sbjct: 3679 MSDPKPLS 3686



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 62/266 (23%), Positives = 93/266 (34%), Gaps = 42/266 (15%)

Query: 2115 HGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG 2174
            H     GP     QP    GL+ P   +  +PG +  P  P G   P      GPA    
Sbjct: 321  HEKSQPGPAKPPAQPS---GLTKP---LAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPA 373

Query: 2175 TAVRQLLPSTA-----TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPY 2228
                   PS+       +    G+  +    P  A  P  TQ     +P+ +  G+  P 
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPA 431

Query: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRY---PAPSRFPIASSVPPAEGPVYLGKP 2285
             + G T  P+       + A +   G T   +      PS+ P  +  PP +       P
Sbjct: 432  KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ-------P 484

Query: 2286 AAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGG 2345
              AK P       P+ P G+A+    P+  P + K     P PA  + Q+P +   P   
Sbjct: 485  GPAKPP-------PQQP-GSAKP---PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-- 531

Query: 2346 SGALSRPGFEKEEASQEERQRKQQEQ 2371
                 +PG  K  A Q    +   +Q
Sbjct: 532  ----QQPGSAKPSAQQPSPAKPSAQQ 553



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 38/147 (25%), Positives = 51/147 (34%), Gaps = 24/147 (16%)

Query: 1485 PSESPTFSPGKMGPR-----ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR 1539
            PS SP+ S     PR     ++ + S Q P P P    P  P  P P P +      P  
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL----PPPTS 2432

Query: 1540 PSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTS-PLCSPTETQPTTHGYSQTT 1598
            P    L  ++ +  +P    T   DA +         S   P+     T P         
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP------PPV 2486

Query: 1599 PPSVSQLP--------PEPPGPPGFPR 1617
            PP  S +P        PEP  PP  P+
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPK 2513



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 17/30 (56%), Positives = 21/30 (70%), Gaps = 2/30 (6%)

Query: 3888 PGADGE--SVFSKILPGGAAEQAGKLTEAV 3915
            PG  GE  +  +KILPGG+AEQ GKL E +
Sbjct: 4524 PGHSGEIGAYIAKILPGGSAEQTGKLMEGM 4553



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 74/330 (22%), Positives = 121/330 (36%), Gaps = 39/330 (11%)

Query: 2931 TTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESL 2990
            + VP  +  +   +  DL + E +  K  KK+       + ++A     EL   + K SL
Sbjct: 2276 SVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSL 2335

Query: 2991 AKDRGGRDYPPLRGLG-EHRDYLSDSELNQLRLQGCTTPAGQFVD-FPATAAAPATPSGP 3048
            ++     D+PP   +    ++ LS +        G   PA Q     P+ ++ PA P   
Sbjct: 2336 SETVF--DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--- 2390

Query: 3049 TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPN 3108
                +P F+  +   SA             Q P  P P   P P  PP    P  P    
Sbjct: 2391 ----RPFFRSSSLDISA-------------QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 3109 QQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV 3168
            +    P       +P+ TT + LF    D+   L+    T++        T     A P 
Sbjct: 2434 KPTILPKKKLTVASPV-TTATPLF----DAVTTLE---TTAVLRSNGLPVTRICTTAPPP 2485

Query: 3169 VP--MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQN 3226
            VP   SS PS   ++     S       P +P+     + +Q P   +P  +   SL  +
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL---PTTTQKPTDIHPKPTG-LSLTSS 2541

Query: 3227 VPRNYVMIDDISELTKDSTSTAPDSQRLEP 3256
            +  N V   D  +L   ++  +P S +  P
Sbjct: 2542 MTLNLVTSADY-KLPSPTSPLSPHSNKSSP 2570


>gi|150378539 piccolo isoform 1 [Homo sapiens]
          Length = 5142

 Score =  737 bits (1903), Expect = 0.0
 Identities = 555/1506 (36%), Positives = 790/1506 (52%), Gaps = 199/1506 (13%)

Query: 2185 ATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRV 2244
            + +R+++G++YS++ TP  +T  ITTQP S+    VR        SG  TA  +TSL   
Sbjct: 3080 SVLRSSNGVVYSSVATPTPSTFAITTQPGSIFSTTVRD------LSGIHTADAVTSL--- 3130

Query: 2245 PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPV- 2303
                      P   +  P P  + I +                       G S  ++ V 
Sbjct: 3131 ----------PAMHHSQPMPRSYFITT-----------------------GASETDIAVT 3157

Query: 2304 GAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEE 2363
            G      L T T  ++        P      +   +   G  S  L  P  +K       
Sbjct: 3158 GIDISASLQTITMESLTAETIDSVPTLTTASEVFPEVV-GDESALLIVPEEDK------- 3209

Query: 2364 RQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIK 2423
                 Q+Q L LERE +ELEK++Q R  EELE ER E+QR RE+E+++VQ++L+ELQ++K
Sbjct: 3210 -----QQQQLDLERELLELEKIKQQRFAEELEWERQEIQRFREQEKIMVQKKLEELQSMK 3264

Query: 2424 HHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPF---PAA 2480
             H+L QQ+EERQAQF +++E LAQQ+LQLEQIQQLQQQL QQLEEQK RQ   +   P+ 
Sbjct: 3265 QHLLFQQEEERQAQFMMRQETLAQQQLQLEQIQQLQQQLHQQLEEQKIRQIYQYNYDPSG 3324

Query: 2481 CEAPGRGPPLAAAE----LAQNGQYW----PPLTHAAFIAMAGPEGLG-------QPREP 2525
              +P      A  E      +  Q+W       T +A +A+  P+  G          + 
Sbjct: 3325 TASPQTTTEQAILEGQYAALEGSQFWATEDATTTASAVVAIEIPQSQGWYTVQSDGVTQY 3384

Query: 2526 VLHRGLPSSAS-----DMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580
            +   G+ S+ S     D+ ++ E+Q +   SG K R     + +        +P   ++I
Sbjct: 3385 IAPPGILSTVSEIPLTDVVVKEEKQPKKRSSGAKVRGQYDDMGE----NMTDDPRSFKKI 3440

Query: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVR-RRRSRLPRHSDS 2639
             DS VQTDDED   R  +SRRRR ++S D SVQTDDED  EW+ P R RR++R+ ++ DS
Sbjct: 3441 VDSGVQTDDEDATDRSYVSRRRRTKKSVDTSVQTDDEDQDEWDMPTRSRRKARVGKYGDS 3500

Query: 2640 GSDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVE 2699
             +++  D T   S        +SS+ +QT+++ SVQTEP    R +P+I   A  D KVE
Sbjct: 3501 MTEA--DKTKPLSK-------VSSIAVQTVAEISVQTEPVGTIR-TPSIR--ARVDAKVE 3548

Query: 2700 IVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFE 2759
            I+++ISAPEKT +G SL CQTE D   Q    PQ +  T+                   +
Sbjct: 3549 IIKHISAPEKTYKGGSLGCQTEADSDTQ---SPQYLSATSPPK----------------D 3589

Query: 2760 KKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNK 2819
            KK+P PLEIGY +HL  +S  QL +  PPKSP+VLYSP+SPLSP + L+++F   E+   
Sbjct: 3590 KKRPTPLEIGYSSHLRADSTVQL-APSPPKSPKVLYSPISPLSPGKALESAFVPYEKPLP 3648

Query: 2820 AHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGS 2879
              +SPQK    D A      P+  K +QRS+SDPKPLSPTA+ES++  F   +     GS
Sbjct: 3649 DDISPQKVLHPDMAKVPPASPKTAKMMQRSMSDPKPLSPTADESSRAPFQYTEGYTTKGS 3708

Query: 2880 QVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKAS 2939
            Q   +  +   +KVKRTLP+PPPEE      G  S      ++ +R +    T+   +A 
Sbjct: 3709 Q--TMTSSGAQKKVKRTLPNPPPEEIS---TGTQSTFSTMGTVSRRRICRTNTM--ARAK 3761

Query: 2940 LLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDY 2999
            +L+++DR+L LVE ES KLRKKQAELDEEEKEIDAKL+YLE+GI +RKE+L K+R  R+ 
Sbjct: 3762 ILQDIDRELDLVERESAKLRKKQAELDEEEKEIDAKLRYLEMGINRRKEALLKEREKRER 3821

Query: 3000 PPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPP 3059
              L+G+ E RDY+SDSE++  R     +  G  ++ P TA         T F Q  F PP
Sbjct: 3822 AYLQGVAEDRDYMSDSEVSSTRPTRIESQHG--IERPRTAP-------QTEFSQ--FIPP 3870

Query: 3060 APQYSAGSGGPT------QNGFPA--HQAPT-YPGPSTYPAPAFPPGASYPAEPGLPNQQ 3110
              Q  +    PT      Q   PA   QAPT Y   S +           P +   P  Q
Sbjct: 3871 QTQTESQLVPPTSPYTQYQYSSPALPTQAPTSYTQQSHFEQQTLYHQQVSPYQT-QPTFQ 3929

Query: 3111 AFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVP 3170
            A           P PT Q + + +P+      QKPRQT+L  LE K+ +NYEVI +   P
Sbjct: 3930 AVATMSFTPQVQPTPTPQPS-YQLPSQMMVIQQKPRQTTLY-LEPKITSNYEVIRNQ--P 3985

Query: 3171 MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRN 3230
            +  AP  T  +      G +   +       +R S++ SP  +  +DS Y  ++ + PRN
Sbjct: 3986 LMIAPVSTDNTFAVSHLGSKYNSLDLRIGLEERSSMASSPISSISADSFYADIDHHTPRN 4045

Query: 3231 YVMIDDISELTKDST--STA-----PDSQRLEPLGPGSSGRPGKEPGE-PGVLDGPTLPC 3282
            YV+IDDI E+TK +   STA      D  + + L   +  R  +E  +    L   +   
Sbjct: 4046 YVLIDDIGEITKGTAALSTAFSLHEKDLSKTDRLLRTTETRRSQEVTDFLAPLQSSSRLH 4105

Query: 3283 CYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTH-------YYGDSDYRHGARVEKYG 3335
             Y + EE+  ED Y+ +     ++     G  +  H       Y+ D+ YRH  + EKY 
Sbjct: 4106 SYVKAEEDPMEDPYELKLLKHQIKQEFRRGTESLDHLAGLSHYYHADTSYRHFPKSEKYS 4165

Query: 3336 PGPMG-PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVS 3394
               +   K  +K L  A +  K+SKH+K  ++ K+SKFSPI+E++D+E D +SY   + S
Sbjct: 4166 ISRLTLEKQAAKQLPAAILYQKQSKHKKSLIDPKMSKFSPIQESRDLEPDYSSYMTSSTS 4225

Query: 3395 S--SLVSRGRKFQDEITYGLKKNVYEQQKYYGMS-----------SRDAVED--DRIYGG 3439
            S   + SR R  QD+IT+GL+KN+ +QQK+ G S            R A++D  D+ Y  
Sbjct: 4226 SIGGISSRARLLQDDITFGLRKNITDQQKFMGSSLGTGLGTLGNTIRSALQDEADKPYSS 4285

Query: 3440 SSRSR---APSAYSGEKLS-SHDFSGWGKGYE-REREAVE-----RLQKAGPKPSSLSMA 3489
             SRSR    PS+  G  LS   D S      + +E EA++         A  KP+SL ++
Sbjct: 4286 GSRSRPSSRPSSVYGLDLSIKRDSSSSSLRLKAQEAEALDVSFSHASSSARTKPTSLPIS 4345

Query: 3490 HSRVRPPMRSQASEEESPVSPLGRP----RPAGGPLPP-GGDTCPQFCSSHSMPDVQEHV 3544
             SR R P+ +Q SEEESP+SP+G+P    R A GPLPP   DT  QF SSHS+P+VQ+H+
Sbjct: 4346 QSRGRIPIVAQNSEEESPLSPVGQPMGMARAAAGPLPPISADTRDQFGSSHSLPEVQQHM 4405

Query: 3545 KDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVS 3604
            ++  R   Y R+  +I+DD    +SDSEAYHL +EETDWFDKPR++R +      GH + 
Sbjct: 4406 REESRTRGYDRDIAFIMDDFQHAMSDSEAYHLRREETDWFDKPRESRLE-----NGHGLD 4460

Query: 3605 SSSQKR 3610
                +R
Sbjct: 4461 RKLPER 4466



 Score =  583 bits (1504), Expect = e-166
 Identities = 566/1914 (29%), Positives = 804/1914 (42%), Gaps = 324/1914 (16%)

Query: 59   PVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASP--TPKQASATTPGHESP----RET 112
            PVP   P P     P +T+  +    P   Q +      PKQ  +  P  + P    ++ 
Sbjct: 652  PVPS-SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQP 710

Query: 113  RAQGPAGQEADGPRRTLQVDSRTQRSG-RSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCP 171
               G    +A  P    + DS ++ +  + PSV  ++   P +     Q   +  +T   
Sbjct: 711  TLHGSPSAKAKQPP---EADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTT--D 765

Query: 172  ICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMT 231
            +  +S  T+ P  P+    +Q   K        P       K         ++    D  
Sbjct: 766  LVSSSSATTKPDIPSSKVQSQAEEKT------TPPLKTDSAKPSQSFPPTGEKVSPFDSK 819

Query: 232  TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
              PR  S  ++ S    P  S             S+G     P  ++ E  +A +   P 
Sbjct: 820  AIPRPASDSKIIS---HPGPS-----------SESKGQKQVDPVQKKEEPKKAQTKMSPK 865

Query: 292  QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQT--------Q 343
              A P   G  +P  P+PT   T  P P     P + +      LG+            Q
Sbjct: 866  PDAKPMPKGSPTPPGPRPTAGQTV-PTPQQSPKPQEQSRRFSLNLGSITDAPKSQPTTPQ 924

Query: 344  EGLTGKLFGLGASLLTQASTLMSV--QPEADTQGQP-APSKGTPKIVFNDASKEAGPKPL 400
            E +TGKLFG GAS+ +QAS L+S   QP   +Q  P AP K  P       + +  PK  
Sbjct: 925  ETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPA-PSQPPTSQGPPKST 983

Query: 401  GSGPGPGPA-----------PGA-KTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
            G  P P PA           P A K EP A   P        K                 
Sbjct: 984  GQAP-PAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQK 1042

Query: 449  SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508
            +    K +  PK  + CPLC+ ELN+GSK P N+NTCT C+ QVCNLCGFNPTPHL E  
Sbjct: 1043 AVLPTKLEKSPKPESTCPLCKTELNIGSKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 509  EWLCLNCQTKRLLEGSLGE--------------PTPLPPPTSQQ---------------- 538
            EWLCLNCQT+R + G LG+              P P+P  +S Q                
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVKLVKKQEQ 1162

Query: 539  -----------------------PPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKAS-- 573
                                   PP+    +    S L++     L Q   PLP +    
Sbjct: 1163 EVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASAL-QEKKPLPEEKKLI 1221

Query: 574  ------------PLSTKASPLPS--KASPQAKPLRASEPSK------------------T 601
                        PL  +  P P   K  P+AK     E                      
Sbjct: 1222 PEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQIAEEKLEGRVA 1281

Query: 602  PSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEP-ATPVVKAVPEAPKGGE 660
            P +VQE K +  TK E +P   P++ P       K+   + +P  T     V    +  E
Sbjct: 1282 PKTVQEGK-QPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQVEPGKEKTE 1340

Query: 661  AEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQL------DSAGVT 714
             ED      S    +SPQ LSDTGYSSDGISSS  EI  ++  + + +      DS    
Sbjct: 1341 KEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSLIPTDEKDILKGLKKDSFSQE 1400

Query: 715  GPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRP------HSLSITP 768
               P SPS++ K+ S++  +L+AQ    ++      +   E   ++P       SLS T 
Sbjct: 1401 SS-PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQPKDQEKTQSLSETL 1459

Query: 769  EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSD-----DFGSQLR-----HDYVEDS 818
            E   S+EE+++  EE +D+    ++  QQD   S D     +F   +      +D VE+S
Sbjct: 1460 EITISEEEIKESQEERKDTF---KKDSQQDIPSSKDHKEKSEFVDDITTRREPYDSVEES 1516

Query: 819  SEGGLSPLPPQPPARAAELT---------------DEDFMRRQILEMSAEED-NLEEDDT 862
            SE   SP+P +    +   +               +EDF+R+QI+EMSA+ED +  EDD 
Sbjct: 1517 SESENSPVPQRKRRTSVGSSSSDEYKQEDSQGSGEEEDFIRKQIIEMSADEDASGSEDDE 1576

Query: 863  ATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGS-----AEA 917
                +      + +   +   +   +  A   RRL   ++T  +E      S      EA
Sbjct: 1577 FIRNQLKEISSSTESQKKEETKGKGKITAGKHRRLTRKSSTSIDEDAGRRHSWHDEDDEA 1636

Query: 918  TDGSGTLQ-----------------GGLRRFKTIELNSTGSYGHELDLGQGPDPS-LDRE 959
             D S  L+                 GGLRRFKTIELNST +  +  +  Q       D E
Sbjct: 1637 FDESPELKYRETKSQESEELVVTGGGGLRRFKTIELNSTIADKYSAESSQKKTSLYFDEE 1696

Query: 960  PELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEA 1019
            PELEMESLT SPEDRSRGE SS+L AS  S+T GTSPTS+SSL+EDSDSSPS ++   E+
Sbjct: 1697 PELEMESLTDSPEDRSRGEGSSSLHAS--SFTPGTSPTSVSSLDEDSDSSPSHKKG--ES 1752

Query: 1020 KQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
            KQQRKARHR HGPLLPTIEDSSEEEELREEEELL+EQEK RE+EQQ+ +S+++K+++DK+
Sbjct: 1753 KQQRKARHRPHGPLLPTIEDSSEEEELREEEELLKEQEKQREIEQQQRKSSSKKSKKDKD 1812

Query: 1080 ELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEAL 1139
            ELRAQRRRER KTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY  SPS++S+ E  
Sbjct: 1813 ELRAQRRRERPKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEY--SPSIESDPEGF 1870

Query: 1140 DGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQ 1199
            +  P ++ +    Y LPT +SLYSPT+  S       S + LKSAEE YEEMM K    +
Sbjct: 1871 EISPEKIIEVQKVYKLPTAVSLYSPTDEQS-IMQKEGSQKALKSAEEMYEEMMHKTH--K 1927

Query: 1200 RQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAA---------------QPA 1244
             +   AA  R          G   +  + Y+   +  Y  +                Q  
Sbjct: 1928 YKAFPAANERDEVFEKEPLYGGMLIEDYIYESLVEDTYNGSVDGSLLTRQEEENGFMQQK 1987

Query: 1245 AEGTPASLGAAVYEEILQ-------------TSQSIVRMRQASSRDLAFAE--------- 1282
                   L   +YE+ +Q             +  S+V      S      E         
Sbjct: 1988 GREQKIRLSEQIYEDPMQKITDLQKEFYELESLHSVVPQEDIVSSSFIIPESHEIVDLGT 2047

Query: 1283 ---DKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQ----------------------L 1317
                 ++E++ L+A++AY + MK+    LTPG+SPTQ                       
Sbjct: 2048 MVTSTEEERKLLDADAAYEELMKRQQMQLTPGSSPTQAPIGEDMTESTMDFDRMPDASLT 2107

Query: 1318 AAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE--TQDPLKLHSSPASPSSASKEIGMPFS 1375
            ++ +S ++ T S SS    IPDV++TQHF+ E    + +  ++       A + + + +S
Sbjct: 2108 SSVLSGASLTDSTSSATLSIPDVKITQHFSTEEIEDEYVTDYTREIQEIIAHESLILTYS 2167

Query: 1376 QGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPT-TANYGSQTED 1434
            +    P+ +A +  P+  P    +  S   +  S SP +T  S     T   +  ++ ED
Sbjct: 2168 E----PSESATSVPPSDTP-SLTSSVSSVCTTDSSSPITTLDSITTVYTEPVDMITKFED 2222

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSP- 1493
              +  S     G         +   +   P   RA +     S     SS  ES    P 
Sbjct: 2223 SEEISSSTYFPGSIIDYPEEISVSLDRTAPPDGRASADHIVISLSDMASSIIESVVPKPE 2282

Query: 1494 GKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQE 1553
            G +    + +       P   +      G         +  +      T   + +     
Sbjct: 2283 GPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSLSETVFDH 2342

Query: 1554 APFMVITL------------ASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601
             P  VI L            + +   Q +      S SP  S    +P    + +++   
Sbjct: 2343 PPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--RPFFRSSSLD 2400

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTP 1661
            +S  PP PP PP  P  P      P         P    +  + + +P        P T 
Sbjct: 2401 ISAQPPPPPPPPPPPPPPPPPPPPP---------PLPPPTSPKPTILPKKKLTVASPVTT 2451

Query: 1662 GTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLV 1715
             T + D  T ++ T  +L   G+ +T +   A        P+P + S+    LV
Sbjct: 2452 ATPLFDAVTTLE-TTAVLRSNGLPVTRICTTAP------PPVPPKPSSIPSGLV 2498



 Score =  224 bits (571), Expect = 1e-57
 Identities = 296/1195 (24%), Positives = 451/1195 (37%), Gaps = 142/1195 (11%)

Query: 18   PGGAGPGPGPGPG------PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGP 71
            PG   P   PGP       PG GK P+  AG G+  A     +     +PGP   P   P
Sbjct: 425  PGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQP 484

Query: 72   GPGSTSRRL--DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTL 129
            GP     +     K P     +  P P+Q     P  + P  T+   P  Q+    + + 
Sbjct: 485  GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK---PPSQQPGSAKPSA 541

Query: 130  QVDSRTQRSGRSPS--VSPDRGSTPTSPYSVPQIAPLPSS-----TLCPICKTSD-LTST 181
            Q  S  + S +  +  VS      P  P +V   A  P S     T+CP+C T++ L   
Sbjct: 542  QQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHV 601

Query: 182  PSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQ 241
            P + NFNTCT+C   VC+ CGFNPNPHLT+VKEWLCLNCQM+RALG D+   P S   + 
Sbjct: 602  PEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKL 661

Query: 242  LHSPALSPA-----------HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGP 290
              +P  + +            SP K    K D  ++  P  P P  +Q     + S    
Sbjct: 662  KTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPS---- 717

Query: 291  AQAAAPPEVGRVS-PQPP-QPTKPSTAEPRPPAGEAP-----AKSATAVPAGLGAT---- 339
            A+A  PPE   +S P PP +P+ PS  +  P A + P      K  T + +   AT    
Sbjct: 718  AKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPD 777

Query: 340  -------EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFND-A 391
                    Q +E  T         L T ++      P    +  P  SK  P+   +   
Sbjct: 778  IPSSKVQSQAEEKTT-------PPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKI 830

Query: 392  SKEAGPKPLGSGPGPGPAPGAKTEP---GARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
                GP     G         K EP     +M P      +PK G  T P       Q  
Sbjct: 831  ISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPK-GSPTPPGPRPTAGQTV 889

Query: 449  SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVC-NLCGFNPTPHLVEK 507
                  PK   + R      +  LN+GS + A  +  TT +  V   L GF  +      
Sbjct: 890  PTPQQSPKPQEQSR------RFSLNLGSITDAPKSQPTTPQETVTGKLFGFGAS------ 937

Query: 508  TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR---ASGTSPLKQKGPQGLGQP 564
                 +  Q   L+  + G+    P P SQ  P GAP +   A    P  Q  P+  GQ 
Sbjct: 938  -----IFSQASNLI-STAGQ----PGPHSQSGP-GAPMKQAPAPSQPPTSQGPPKSTGQ- 985

Query: 565  SGPLPAKASPLSTKA-SPLPSKASP---QAKPLRASEPSKTPSSVQEKKTR--------V 612
            + P PAK+ P+  +  +P   K  P   QA  ++ +E  K P  +++ K+         +
Sbjct: 986  APPAPAKSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKDSKSLTAEPQKAVL 1045

Query: 613  PTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQD 672
            PTK E  PK  PE+T     P  K+ +       P      E     +  +L G   +  
Sbjct: 1046 PTKLEKSPK--PEST----CPLCKTELNIGSKDPPNFNTCTECK--NQVCNLCGFNPTPH 1097

Query: 673  ASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
             +   + L     +   IS    +I     +++    S     P  P P+E     +++ 
Sbjct: 1098 LTEIQEWLCLNCQTQRAISGQLGDI-----RKMPPAPSGPKASP-MPVPTESSSQKTAVP 1151

Query: 733  PLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSA--EW 790
            P ++       E          E+ K+      I P      ++ E  LE+D+ SA  E 
Sbjct: 1152 PQVKLVKKQEQEVKTEAEKVILEKVKETLSMEKIPPMVTTDQKQEESKLEKDKASALQEK 1211

Query: 791  RRRREQQDTAESSDDFGSQLRHDYVEDSSEGGL-SPLPPQPPARAAELTDEDFMRRQILE 849
            +   E++      +   S+ +   +E+         L P+    A E    D ++ Q+  
Sbjct: 1212 KPLPEEKKLIPEEEKIRSEEKKPLLEEKKPTPEDKKLLPEAKTSAPEEQKHDLLKSQVQI 1271

Query: 850  MSAEEDNLEEDDTATSGR--GLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
               + +      T   G+       G   G P+  P+   +     K +     T   ++
Sbjct: 1272 AEEKLEGRVAPKTVQEGKQPQTKMEGLPSGTPQSLPKEDDKTTKTIKEQPQPPCTAKPDQ 1331

Query: 908  LLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESL 967
            + P     E  D         +      L+ TG     +    G  PSL   P  E + L
Sbjct: 1332 VEPGKEKTEKEDDKSDTSSSQQPKSPQGLSDTGYSSDGISSSLGEIPSL--IPTDEKDIL 1389

Query: 968  TGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS-----DSSPSRRQRLEEAKQQ 1022
             G  +D    E S     S+PS  +    T LS LE  +     + S  + Q  E + +Q
Sbjct: 1390 KGLKKDSFSQESS----PSSPSDLAKLESTVLSILEAQASTLADEKSEKKTQPHEVSPEQ 1445

Query: 1023 RKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR 1082
             K + ++   L  T+E +  EEE++E +E    ++  ++  QQ I S+  K  ++K E  
Sbjct: 1446 PKDQEKTQS-LSETLEITISEEEIKESQE--ERKDTFKKDSQQDIPSS--KDHKEKSEFV 1500

Query: 1083 AQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAE 1137
                  R        S   + SP  + ++   +     SS  EY    S  S  E
Sbjct: 1501 DDITTRREPYDSVEESSESENSPVPQRKRRTSVGS---SSSDEYKQEDSQGSGEE 1552



 Score =  171 bits (433), Expect = 1e-41
 Identities = 173/628 (27%), Positives = 235/628 (37%), Gaps = 116/628 (18%)

Query: 242 LHSPALSPAH--SPAKQPLGKPDQERSR-GPGGP-------------QPG---------- 275
           L SP+  P    +P K P  +P  E+S+ GP  P             QPG          
Sbjct: 298 LPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPG 357

Query: 276 ---------------SRQAETARATS-VPGPAQAAAPPEVGRVSPQPPQPTKPSTAE--- 316
                          ++Q  + + +S  PGP   A PP VG+   Q P P KP T +   
Sbjct: 358 TTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGT 417

Query: 317 PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASL-LTQASTLMSVQPEADTQG 375
           P+P A + P   + A   G   T   Q G  GK+    A    T A      +P +   G
Sbjct: 418 PKPLA-QQPGLQSPAKAPGPTKTPVQQPG-PGKIPAQQAGPGKTSAQQTGPTKPPSQLPG 475

Query: 376 QPAPSKGTPKIVFNDASKEAGPKPLGSGPG--------PGPAPGAKTEPGARMGPGSGPG 427
              P    P        +    KP    PG        PGPA  +  +PG+   P   PG
Sbjct: 476 PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPSQQPG 535

Query: 428 ALPKTGGTTSPKHGRAEHQ----------------AASKAAAKPKTMPKERAICPLCQ-A 470
           +   +    SP    A+                    S +A +P +    + ICPLC   
Sbjct: 536 SAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTT 595

Query: 471 ELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP 530
           EL +     AN+NTCT C+  VC+LCGFNP PHL E  EWLCLNCQ KR L G L     
Sbjct: 596 ELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPS 655

Query: 531 LPPPTSQQPPVGAPHRAS-------GTSPLKQKGP-QGLG---QPSGPLPAKASPLSTKA 579
            P P  +  PV      S        TSP K   P Q L    +P  P P    P    +
Sbjct: 656 SPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGS 715

Query: 580 SPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGV 639
               +K  P+A  L    P K P SV  ++ + P  A+  PK P    PT  T  V S  
Sbjct: 716 PSAKAKQPPEADSLSKPAPPKEP-SVPSEQDKAPV-ADDKPKQPKMVKPT--TDLVSSSS 771

Query: 640 RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTG-----YSSDGISSSQ 694
              +P       +P +    +AE+    P   D+++  QS   TG     + S  I    
Sbjct: 772 ATTKP------DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPA 825

Query: 695 SEITGVVQQEVEQLDSAGVTGPHPPSPS----EIHKVGSSMRPLLQAQGLAPSERSKPLS 750
           S             DS  ++ P P S S    ++  V     P      ++P   +KP+ 
Sbjct: 826 S-------------DSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMP 872

Query: 751 SGTGEEQKQRPHSLSITPEAFDSDEELE 778
            G+      RP +    P    S +  E
Sbjct: 873 KGSPTPPGPRPTAGQTVPTPQQSPKPQE 900



 Score =  110 bits (274), Expect = 4e-23
 Identities = 189/740 (25%), Positives = 286/740 (38%), Gaps = 151/740 (20%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P  P   P     P     PTS   +   ++P  ++T      T  PL    +    ++ 
Sbjct: 2411 PPPPPPPPPPPPPPPPLPPPTSPKPT---ILPKKKLTVASPVTTATPLFDAVTTLETTAV 2467

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTA 1426
             +  G+P ++   T A   V P P+ +P G +    P   E S  P +        PTT 
Sbjct: 2468 LRSNGLPVTR-ICTTAPPPVPPKPSSIPSGLVFTHRP---EPSKPPIAPKPVIPQLPTTT 2523

Query: 1427 NYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPS 1486
                +  D+   P+GL+           SA   +   P P+           PLSP S  
Sbjct: 2524 Q---KPTDIHPKPTGLSLTSSMTLNLVTSA---DYKLPSPTS----------PLSPHSNK 2567

Query: 1487 ESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
             SP FS        T  +   T        +P  PG PT S      T  P    +  LV
Sbjct: 2568 SSPRFSKS-----LTETYVVIT--------LPSEPGTPTDSSASQAITSWPLGSPSKDLV 2614

Query: 1547 WQESSQEAPFMVITLASD-----ASSQTRMVHASAST---SPLCSPTETQ--PTTHGYSQ 1596
                S E  F V+   +      +S QT  +  +  T   +P+ +P+  Q  PT+     
Sbjct: 2615 ----SVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAPTSVTQFL 2670

Query: 1597 TTPPSVSQLPPEPPGPP--GFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRV 1654
            TT  S +++       P  G   +       PLAL        +NI L +          
Sbjct: 2671 TTEVSKTEVSATRSTAPSVGLSSISITIPPEPLAL--------DNIHLEK------PQYK 2716

Query: 1655 EPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPL 1714
            E G       V+DLRT  K   +  TD+ +DL++  ++ ++  +  + + G+Q +AVQP 
Sbjct: 2717 EDGKLQLVGDVIDLRTVPK-VEVKTTDKCIDLSASTMDVKRQ-ITANEVYGKQISAVQPS 2774

Query: 1715 VINLNAQEH----TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVC 1770
            +INL+          LAT T   +T  +S       + +V  +   +         +P+ 
Sbjct: 2775 IINLSVTSSIVTPVSLATETVTFVTCTASASYTTGTESLVGAEHAMT---------TPLQ 2825

Query: 1771 LAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLP-NQVAPLARRDVLIT-QMGT-AQSI 1827
            L   K  E      PYR                +P +QV P+AR +  I   +GT A ++
Sbjct: 2826 LTTSKHAE-----PPYR----------------IPSDQVFPIAREEAPINLSLGTPAHAV 2864

Query: 1828 GL---KPGPVPEPGAEPHRATPAELRSHALPG------ARKPHTVVVQMGEGTAGTVTTL 1878
             L   KP  VP  G   +  T + +      G        K H  VV M E T+  +T +
Sbjct: 2865 TLAITKPVTVPPVGV-TNGWTDSTVSQGITDGEVVDLSTTKSHRTVVTMDESTSSVMTKI 2923

Query: 1879 LPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSS 1938
            + +E    +DLT  R   +  CCD+VYKLPFG SCT    PA ++PE             
Sbjct: 2924 IEDEK--PVDLTAGR---RAVCCDVVYKLPFGRSCTAQ-QPATTLPEDR----------- 2966

Query: 1939 SPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHA 1998
               +G RD        Y+         ++   PY     G +  SMSDTNLAEAG  ++ 
Sbjct: 2967 ---FGYRDDH------YQ---------YDRSGPYGYRGIGGMKPSMSDTNLAEAGHFFYK 3008

Query: 1999 QRIGQLFQGPGRDSAMDLSS 2018
             +        G D+A+DL+S
Sbjct: 3009 SK-NAFDYSEGTDTAVDLTS 3027



 Score = 79.7 bits (195), Expect = 5e-14
 Identities = 142/656 (21%), Positives = 213/656 (32%), Gaps = 100/656 (15%)

Query: 1   MGNEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPP--SAPAG-GGQLPAAGAARSTAV 57
           MGNE SLEG      LP G A      G   GAG P   + PAG    L          +
Sbjct: 1   MGNEASLEGEG----LPEGLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEERRQI 56

Query: 58  PPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP 117
             V     G   G  P           P   +  +    ++  ++ P  +S R      P
Sbjct: 57  AAVMSRAQGLPKGSVP-----------PAAAESPSMHRKQELDSSHPPKQSGRPPDPGRP 105

Query: 118 AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSD 177
           A       R T    S  +  GRSPS    + S   +       + +    L  +   S 
Sbjct: 106 AQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKSSMMPGFLSEVNALSA 165

Query: 178 LTS-----------TPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRAL 226
           ++S           + S+ +    T+    V  + G         +++        Q+  
Sbjct: 166 VSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGP 225

Query: 227 GMD---MTTAPRSKSQQQLHSPALSPAHS--PAKQPLGKPDQERSRGP---GGPQPGSRQ 278
           G D       P+S S QQ       P  +  P + P   P  + ++ P      +P ++Q
Sbjct: 226 GRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQ 285

Query: 279 AETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGA 338
           A+  R  SV     + + P + + +P  P   +P   + +P   + PA+     P+GL  
Sbjct: 286 ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ-----PSGLTK 340

Query: 339 TEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
               Q G          +    A  L   +P A   G   PS           S++ GPK
Sbjct: 341 PLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKPS-----------SEQPGPK 389

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
            L   PG G  P  +       GP   P    +  GT  P   +   Q+ +KA    KT 
Sbjct: 390 ALAQPPGVGKTPAQQP------GPAKPP---TQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
            ++     +   +   G  S                     P   L              
Sbjct: 441 VQQPGPGKIPAQQAGPGKTSAQQTGPT-------------KPPSQL-------------- 473

Query: 519 RLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS-PLKQKGPQGLGQPSGPLPAKASPLST 577
                    P P  PP  Q  P   P +  G++ P  Q+       P  P PAK SP   
Sbjct: 474 ---------PGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQP 524

Query: 578 KASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
            ++  PS+    AKP  A +PS    S Q+    V       P  PP  +P+   P
Sbjct: 525 GSTKPPSQQPGSAKP-SAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQP 579



 Score = 70.5 bits (171), Expect = 3e-11
 Identities = 147/676 (21%), Positives = 235/676 (34%), Gaps = 117/676 (17%)

Query: 956  LDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQR 1015
            +  E  LE E L   PE    G  ++       S     S T++ +  E   S  S  +R
Sbjct: 1    MGNEASLEGEGL---PE----GLAAAAAAGGGASGAGSPSHTAIPAGMEADLSQLSEEER 53

Query: 1016 LEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTR 1075
             + A    +A+    G + P   +S      +E +     ++  R  +  R         
Sbjct: 54   RQIAAVMSRAQGLPKGSVPPAAAESPSMHRKQELDSSHPPKQSGRPPDPGRPAQPGLSKS 113

Query: 1076 RDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135
            R  +  R++++       PS +S  E  S T+       ++E H+SS       P   SE
Sbjct: 114  RTTDTFRSEQKLPGRS--PSTISLKESKSRTD-------LKEEHKSSMM-----PGFLSE 159

Query: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKA 1195
              AL    S + K             ++P +  S S             E + EE  +K 
Sbjct: 160  VNALSAVSSVVNK-------------FNPFDLISDS-------------EASQEETTKKQ 193

Query: 1196 ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE-------YQDTTDREYGQAAQPAAEGT 1248
            +++Q++QG+  G   P   P Q   P+ +   +        QD T +          +  
Sbjct: 194  KVVQKEQGKPEGIIKP---PLQQQPPKPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQ 250

Query: 1249 PASLGAAVY--EEILQTSQSIVRMRQASSR------DLAFAEDKKKE-----KQFLNAES 1295
            P   G  +    +  QT  + + +++ +SR      D+   E  K       K  +   +
Sbjct: 251  PPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGESVKPSLPSPSKPPIQQPT 310

Query: 1296 AYMDPMKQNG------GPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE 1349
                P +Q G      GP  P   P+ L  P++           G V P V+        
Sbjct: 311  PGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLA--------QQPGTVKPPVQ-----PPG 357

Query: 1350 TQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERS 1409
            T  P      PA P +       P S+ PG P   A  P     P     PA P  +++ 
Sbjct: 358  TTKPPAQPLGPAKPPAQQTGSEKPSSEQPG-PKALAQPPGVGKTPAQQPGPAKPP-TQQV 415

Query: 1410 PSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
             +P   A   G        G     + Q   G   A +A   K  +++   G T  PS+ 
Sbjct: 416  GTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGK--TSAQQTGPTKPPSQL 473

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                  + PP     P++ P   PG   P +    ST+ P        P+ PG   PSP 
Sbjct: 474  PG---PAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPP--------PQQPGPAKPSPQ 522

Query: 1530 VAQGTQTP-HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPL----CSP 1584
                T+ P  +P + +   Q+ S   P         A   T+ V  + S  PL     SP
Sbjct: 523  QPGSTKPPSQQPGSAKPSAQQPSPAKP--------SAQQSTKPVSQTGSGKPLQPPTVSP 574

Query: 1585 TETQPTTHGYSQTTPP 1600
            +  QP + G  +T  P
Sbjct: 575  SAKQPPSQGLPKTICP 590



 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 248/1193 (20%), Positives = 383/1193 (32%), Gaps = 269/1193 (22%)

Query: 2751 TPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTS 2810
            +P  +   E K    L+  +++ + P  LS++       +   + S V+  +P  L+  S
Sbjct: 129  SPSTISLKESKSRTDLKEEHKSSMMPGFLSEV------NALSAVSSVVNKFNPFDLISDS 182

Query: 2811 FASSERLNKAHVSPQKHFTADSAL----RQQTLPRPMKTLQRSLSDPKPLSPTAEESAKE 2866
             AS E   K     QK       +     QQ  P+P+   Q    DP             
Sbjct: 183  EASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPL------------ 230

Query: 2867 RFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRG 2926
                   Q G    +S+  P     K+K    S PP        G   P           
Sbjct: 231  ------QQDGTPKSISSQQPE----KIK----SQPP--------GTGKP----------- 257

Query: 2927 LTGPTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQR 2986
            + GPT  P T  + L         ++ ++++ + KQA++   E  +   L       +  
Sbjct: 258  IQGPTQTPQTDHAKLP--------LQRDASRPQTKQADIVRGES-VKPSLP------SPS 302

Query: 2987 KESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQF-------VDFPATA 3039
            K  + +   G+  PP +  G  +     ++    +  G T P  Q        V  P T 
Sbjct: 303  KPPIQQPTPGK--PPAQQPGHEKSQPGPAK-PPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 3040 AAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG--PSTYPAPAFPPG 3097
              PA P GP        +PPA Q  +      Q G  A   P   G  P+  P PA PP 
Sbjct: 360  KPPAQPLGPA-------KPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP- 411

Query: 3098 ASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKV 3157
                 + G P   A +P      + P PT      P P    A    P +TS        
Sbjct: 412  ---TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTK 468

Query: 3158 PTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKV-PEVPRAGDRGSVSQSPAPTYPS 3216
            P +   +  P  P    P      GPA     + G   P   + G      Q P P  PS
Sbjct: 469  PPSQ--LPGPAKPPPQQP------GPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPS 520

Query: 3217 DSHYTSLE--QNVPRNYVMIDDISELTKDST--STAPDSQRL--EPLGPGSSGRPGKEPG 3270
                 S +     P +           K S   ST P SQ    +PL P +     K+P 
Sbjct: 521  PQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPP 580

Query: 3271 EPGVLDGPTLPCCYARG-----EEESEEDS-------------YDP-------------- 3298
              G L     P C          E++  ++             ++P              
Sbjct: 581  SQG-LPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLN 639

Query: 3299 ----RGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAIS 3354
                R  GG L  + S+ +P        +     + V K  P P     P K  AP    
Sbjct: 640  CQMKRALGGDLAPVPSSPQPKLK----TAPVTTTSAVSKSSPQPQQTS-PKKDAAPKQDL 694

Query: 3355 SKRSKHRKQG--MEQKISKFSPIEEAKDV-ESDLASYPPPAVSSSLVSRGRK--FQDEIT 3409
            SK  + +K    ++Q     SP  +AK   E+D  S P P    S+ S   K    D+  
Sbjct: 695  SKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQDKAPVADDKP 754

Query: 3410 YGLK--KNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGKGYE 3467
               K  K   +       +++  +   ++   +     P   +     S  F   G    
Sbjct: 755  KQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTG---- 810

Query: 3468 REREAVERLQ-KAGPKPSSLSMAHSRVRPPMRSQASEEESPV---------------SPL 3511
               E V     KA P+P+S S   S   P   S+  ++  PV                P 
Sbjct: 811  ---EKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVDPVQKKEEPKKAQTKMSPKPD 867

Query: 3512 GRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDS 3571
             +P P G P PPG    P+  +  ++P  Q+  K   ++  +    G I D         
Sbjct: 868  AKPMPKGSPTPPG----PRPTAGQTVPTPQQSPKPQEQSRRFSLNLGSITDAPK------ 917

Query: 3572 EAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPH 3631
                  Q  T     P++  + +    G    S +S     A                PH
Sbjct: 918  -----SQPTT-----PQETVTGKLFGFGASIFSQASNLISTAGQP------------GPH 955

Query: 3632 DEGGPG---RHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA 3688
             + GPG   + A A        G    + TG+ P                      P+ A
Sbjct: 956  SQSGPGAPMKQAPAPSQPPTSQG--PPKSTGQAP----------------------PAPA 991

Query: 3689 PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK---AEPQAQP 3745
             ++P K +   P++ +    +  +         KK        P    SK   AEPQ   
Sbjct: 992  KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKK-------PPPIKDSKSLTAEPQKAV 1044

Query: 3746 QLQGRQAAPGPQQSQSPSSRQIPSGAASRQP-------QTQQQQQGLGLQPPQQALTQAR 3798
                 + +P P+ +      ++  G  S+ P       + + Q   L    P   LT+ +
Sbjct: 1045 LPTKLEKSPKPESTCPLCKTELNIG--SKDPPNFNTCTECKNQVCNLCGFNPTPHLTEIQ 1102

Query: 3799 ----LQQQSQPTTRGS-------APAASQPAGKPQPGPSTATGPQPAGPPRAE 3840
                L  Q+Q    G         PA S P   P P P+ ++  + A PP+ +
Sbjct: 1103 EWLCLNCQTQRAISGQLGDIRKMPPAPSGPKASPMPVPTESSSQKTAVPPQVK 1155



 Score = 59.3 bits (142), Expect = 7e-08
 Identities = 77/279 (27%), Positives = 110/279 (39%), Gaps = 42/279 (15%)

Query: 3655 GRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYP--------SSAEYS 3706
            G+   ++PG   ++P         A+P +QPS     P   QPG          ++   +
Sbjct: 312  GKPPAQQPGHEKSQPGP-------AKPPAQPSGL-TKPLAQQPGTVKPPVQPPGTTKPPA 363

Query: 3707 QPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQ--SQSPSS 3764
            QP   +      + S+K S +   GP AL         P  Q   A P  QQ  +  P +
Sbjct: 364  QPLGPAKPPAQQTGSEKPSSE-QPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 3765 RQIPSGAASRQP---QTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSA-PAASQPAGK 3820
            +Q    + ++ P   +T  QQ G G  P QQA       QQ+ PT   S  P  ++P  +
Sbjct: 423  QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQ 482

Query: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
             QPGP+     QP             G+AK P Q       P   PGPA  K   +  G+
Sbjct: 483  -QPGPAKPPPQQP-------------GSAKPPSQQPGSTKPPPQQPGPA--KPSPQQPGS 526

Query: 3881 PGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFG 3919
               P+ QPG+   S      P  A   A + T+ VS  G
Sbjct: 527  TKPPSQQPGSAKPSAQQ---PSPAKPSAQQSTKPVSQTG 562



 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 96/442 (21%), Positives = 152/442 (34%), Gaps = 70/442 (15%)

Query: 3477 QKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHS 3536
            +K+ P P+      S +  P+  Q    + PV P G  +P   PL P      Q  S   
Sbjct: 322  EKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEKP 381

Query: 3537 MPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFR 3596
              +     + GP+A A     G          + ++     +  T     P+        
Sbjct: 382  SSE-----QPGPKALAQPPGVGK---------TPAQQPGPAKPPTQQVGTPKPLAQQP-- 425

Query: 3597 HHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSG- 3655
                  + S ++  GP +       + P  G  P  + GPG+ ++ +        +  G 
Sbjct: 426  -----GLQSPAKAPGPTKTPV----QQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGP 476

Query: 3656 -RHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSA 3714
             +   ++PG   AKP  +  G  +  P  QP S    P++  P  PS     QP      
Sbjct: 477  AKPPPQQPG--PAKPPPQQPGSAKP-PSQQPGSTKPPPQQPGPAKPSP---QQPGSTKPP 530

Query: 3715 YHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASR 3774
                  +K  ++Q    P+  +  A+   +P  Q     P    + SPS++Q PS    +
Sbjct: 531  SQQPGSAKPSAQQ----PSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPK 586

Query: 3775 QPQTQQQQQGLGLQPPQQA-----------------------LTQAR----LQQQSQPTT 3807
                      L L  P++A                       LT+ +    L  Q +   
Sbjct: 587  TICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRAL 646

Query: 3808 RGS-APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP 3866
             G  AP  S P  K +  P T T       P+ +QT+  K  A      +AP+    P  
Sbjct: 647  GGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPE----PKK 702

Query: 3867 GPAGVKAGARPGGTPGAPAGQP 3888
             P  VK      G+P A A QP
Sbjct: 703  PPPLVKQPTL-HGSPSAKAKQP 723



 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 107/482 (22%), Positives = 165/482 (34%), Gaps = 60/482 (12%)

Query: 3438 GGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPM 3497
            GG+S + +PS  +       D S   +   R+  AV    +  PK  S+  A +      
Sbjct: 24   GGASGAGSPSHTAIPAGMEADLSQLSEEERRQIAAVMSRAQGLPK-GSVPPAAAESPSMH 82

Query: 3498 RSQASEEESPVSPLGRPRPAGGPLPPG---GDTCPQFCSSHSMPDVQEHV---------K 3545
            R Q  +   P    GRP   G P  PG     T   F S   +P                
Sbjct: 83   RKQELDSSHPPKQSGRPPDPGRPAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRT 142

Query: 3546 DGPRAHAYKREEGYILD--------------DSHCVVSDSEAYHLGQEETDWFDKPRDAR 3591
            D    H      G++ +              +   ++SDSEA    QEET    K +  +
Sbjct: 143  DLKEEHKSSMMPGFLSEVNALSAVSSVVNKFNPFDLISDSEA---SQEETT--KKQKVVQ 197

Query: 3592 SDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHG 3651
             ++ +  G        Q   P         +P ++      +G P   +S +  +     
Sbjct: 198  KEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQ------DGTPKSISSQQPEKIKSQP 251

Query: 3652 RHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRA 3711
              +G+   + P +     HA+   + +A   S+P +  A   +G+   PS    S+P   
Sbjct: 252  PGTGKPI-QGPTQTPQTDHAKLPLQRDA---SRPQTKQADIVRGESVKPSLPSPSKPPIQ 307

Query: 3712 SSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGA 3771
                      + G  ++  GPA      +P AQP    +  A  P   + P     P G 
Sbjct: 308  QPTPGKPPAQQPGHEKSQPGPA------KPPAQPSGLTKPLAQQPGTVKPPVQ---PPGT 358

Query: 3772 ASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGP 3831
                 +   Q  G    P QQ  ++    +Q  P      P   +   + QPGP+     
Sbjct: 359  T----KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQ-QPGPAKPPTQ 413

Query: 3832 QPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV----KAGARPGGTPGAPAGQ 3887
            Q   P    Q  G +  AKAP   + P  QP PG  PA      K  A+  G    P+  
Sbjct: 414  QVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQL 473

Query: 3888 PG 3889
            PG
Sbjct: 474  PG 475



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 146/706 (20%), Positives = 236/706 (33%), Gaps = 142/706 (20%)

Query: 290 PAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPA--GLGATEQTQEGLT 347
           P Q+  PP+ GR  P  P  +K  T +      + P +S + +        T+  +E  +
Sbjct: 93  PKQSGRPPDPGR--PAQPGLSKSRTTDTFRSEQKLPGRSPSTISLKESKSRTDLKEEHKS 150

Query: 348 GKLFGLGASLLTQASTLMSVQPE-------ADTQGQPAPSKGTPKIVFNDASKEAG--PK 398
             + G   S +   S + SV  +       +D++     +    K+V  +  K  G    
Sbjct: 151 SMMPGF-LSEVNALSAVSSVVNKFNPFDLISDSEASQEETTKKQKVVQKEQGKPEGIIKP 209

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGP---GALPKTGGTTSPKHGRAEHQAASKAAAKP 455
           PL   P P P P        + GPG  P      PK+  +  P+  +++     K    P
Sbjct: 210 PLQQQP-PKPIP-------KQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGP 261

Query: 456 KTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNC 515
              P+               +K P   +       Q   + G +  P L   ++      
Sbjct: 262 TQTPQTDH------------AKLPLQRDASRPQTKQADIVRGESVKPSLPSPSK------ 303

Query: 516 QTKRLLEGSLGEPTPLPPPTSQQPPVGAP-HRASGTSPLKQKG-PQGLGQPSGPLPAKAS 573
                         P+  PT  +PP   P H  S   P K    P GL +P    P    
Sbjct: 304 -------------PPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVK 350

Query: 574 PLSTKASPLPSKASPQAKPLRASEP------SKTPSSVQEKKT---------RVPTKAEP 618
           P      P P    P A+PL  ++P      S+ PSS Q             + P +   
Sbjct: 351 P---PVQP-PGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPG 406

Query: 619 MPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ 678
             KPP +   TP     + G++    A    K   + P         GK  +Q A     
Sbjct: 407 PAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPG-------PGKIPAQQAGPGKT 459

Query: 679 SLSDTGYSS-----DGISSSQSEITGVVQQEVEQLDSA-------GVTGPHPPSPSEI-- 724
           S   TG +       G +    +  G  +   +Q  SA       G T P P  P     
Sbjct: 460 SAQQTGPTKPPSQLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKP 519

Query: 725 --HKVGSSMRPLLQAQGLAPS------------ERSKPLSSGTGEEQKQRPHSLSIT--- 767
              + GS+  P  Q     PS            + +KP+S  TG  +  +P ++S +   
Sbjct: 520 SPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPVSQ-TGSGKPLQPPTVSPSAKQ 578

Query: 768 ------PEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVED---- 817
                 P+         ++L    + A +    E Q T  S   F        V++    
Sbjct: 579 PPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCL 638

Query: 818 ------SSEGGLSPLP--PQPPARAAELTDEDFMRR---QILEMSAEEDNLEEDDTATSG 866
                 +  G L+P+P  PQP  + A +T    + +   Q  + S ++D   + D + + 
Sbjct: 639 NCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAP 698

Query: 867 R-----GLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE 907
                  L K  T  G P  + +   E  +L K   P   +   E+
Sbjct: 699 EPKKPPPLVKQPTLHGSPSAKAKQPPEADSLSKPAPPKEPSVPSEQ 744



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 59/247 (23%), Positives = 91/247 (36%), Gaps = 33/247 (13%)

Query: 3670 HARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYS--------QPSRASSAYHHASDS 3721
            H     + +  P +   S PA PK  +P  PS  + +        QP          S S
Sbjct: 713  HGSPSAKAKQPPEADSLSKPAPPK--EPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSS 770

Query: 3722 KKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ 3781
               + +     + +QS+AE +  P L+   A P   QS  P+  ++    +   P+    
Sbjct: 771  S-ATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPS--QSFPPTGEKVSPFDSKAIPRPASD 827

Query: 3782 QQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG--PSTATGPQPAGP-PR 3838
             + +    P    ++++ Q+Q  P  +   P  +Q    P+P   P     P P GP P 
Sbjct: 828  SKIISHPGPS---SESKGQKQVDPVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPT 884

Query: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSK 3898
            A QT         PQQ   PQ Q          +     G    AP  QP    E+V  K
Sbjct: 885  AGQT------VPTPQQSPKPQEQSR--------RFSLNLGSITDAPKSQPTTPQETVTGK 930

Query: 3899 ILPGGAA 3905
            +   GA+
Sbjct: 931  LFGFGAS 937



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 171/856 (19%), Positives = 276/856 (32%), Gaps = 133/856 (15%)

Query: 3044 TPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQA----PTYPGPSTYPAPAFPPGAS 3099
            +PS P   Q    +PPA Q       P     PA  +    P    P T   P  PPG +
Sbjct: 300  SPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPLAQQPGTVKPPVQPPGTT 359

Query: 3100 YP-AEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVP 3158
             P A+P  P +   + TG     +  P  ++   P P   + P Q+P          K P
Sbjct: 360  KPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQP-PGVGKTPAQQPGPA-------KPP 411

Query: 3159 TNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQG--KVPEVPRAGDRGSVSQSPAPTYPS 3216
            T       P+       S     GP  +   + G  K+P   +AG   + +Q   PT P 
Sbjct: 412  TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIP-AQQAGPGKTSAQQTGPTKPP 470

Query: 3217 DSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGE---PG 3273
             S      +  P+                   P   +  P  PGS+  P ++PG    P 
Sbjct: 471  -SQLPGPAKPPPQQ------------------PGPAKPPPQQPGSAKPPSQQPGSTKPPP 511

Query: 3274 VLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEK 3333
               GP  P     G  +       P  + G  +       PA       S  +    V +
Sbjct: 512  QQPGPAKPSPQQPGSTKP------PSQQPGSAKPSAQQPSPAKP-----SAQQSTKPVSQ 560

Query: 3334 YGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAV 3393
             G G        K L P  +S    +   QG+ + I       E       L   P  A 
Sbjct: 561  TGSG--------KPLQPPTVSPSAKQPPSQGLPKTICPLCNTTEL------LLHVPEKAN 606

Query: 3394 SSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEK 3453
             ++             +    ++ E +++  ++     +  R  GG       S     K
Sbjct: 607  FNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNC----QMKRALGGDLAPVPSSPQPKLK 662

Query: 3454 LSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGR 3513
             +    +        + +     + A PK         +  PP+  Q +   SP +   +
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 3514 PRPAGG---PLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCV--- 3567
            P  A     P PP   + P      S  D      D P+     +    ++  S      
Sbjct: 723  PPEADSLSKPAPPKEPSVP------SEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKP 776

Query: 3568 -VSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEE 3626
             +  S+     +E+T    K   A+  +     G  VS    K  P   S        + 
Sbjct: 777  DIPSSKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPAS--------DS 828

Query: 3627 GLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRR----AAKPHARDLGRHEARPH 3682
             +  H    PG  + +K  +  D  +       EEP +     + KP A+ + +    P 
Sbjct: 829  KIISH----PGPSSESKGQKQVDPVQKK-----EEPKKAQTKMSPKPDAKPMPKGSPTPP 879

Query: 3683 S-QPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGS----RQAHSGP----- 3732
              +P++   +P   Q   P      Q  R S      +D+ K      ++  +G      
Sbjct: 880  GPRPTAGQTVPTPQQSPKPQE----QSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFG 935

Query: 3733 AALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQ 3792
            A++ S+A       L      PGP     P +    + A S+ P +Q   +  G  PP  
Sbjct: 936  ASIFSQAS-----NLISTAGQPGPHSQSGPGAPMKQAPAPSQPPTSQGPPKSTGQAPPAP 990

Query: 3793 ALTQARLQQQSQPTTRGS-APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA 3851
            A        +S P  + + APAA +   K +  P+         PP  +    SK     
Sbjct: 991  A--------KSIPVKKETKAPAAEKLEPKAEQAPTVKRTETEKKPPPIKD---SKSLTAE 1039

Query: 3852 PQQGRAP-QAQPAPGP 3866
            PQ+   P + + +P P
Sbjct: 1040 PQKAVLPTKLEKSPKP 1055



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 154/705 (21%), Positives = 241/705 (34%), Gaps = 133/705 (18%)

Query: 1351 QDPLKLHSSPASPSSASKE--------IGMPFSQGPGTPATTAVAPCP------------ 1390
            +DPL+   +P S SS   E         G P  QGP     T  A  P            
Sbjct: 227  RDPLQQDGTPKSISSQQPEKIKSQPPGTGKPI-QGPTQTPQTDHAKLPLQRDASRPQTKQ 285

Query: 1391 AGLPRGY-MTPASPAGSE---RSPSPSST-AHSYGHSPTTANYGSQTEDLPQAPSGLAAA 1445
            A + RG  + P+ P+ S+   + P+P    A   GH  +           P  PSGL   
Sbjct: 286  ADIVRGESVKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKP----PAQPSGLT-- 339

Query: 1446 GRAAREKPLSASDGEGGTP-QPSRAYSYFASSSPPLSPSSPSESPTFSPG-------KMG 1497
                  KPL+   G    P QP        ++ PP  P  P++ P    G       + G
Sbjct: 340  ------KPLAQQPGTVKPPVQPP------GTTKPPAQPLGPAKPPAQQTGSEKPSSEQPG 387

Query: 1498 PRATAEFST--QTPSPAPASDMPRSPGAPTPSPMVAQ-GTQTPHRPSTPRL--VWQESSQ 1552
            P+A A+     +TP+  P    P +    TP P+  Q G Q+P +   P    V Q    
Sbjct: 388  PKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPG 447

Query: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
            + P         ++ QT          P   P++             P  ++ PP+ PGP
Sbjct: 448  KIPAQQAGPGKTSAQQT---------GPTKPPSQL------------PGPAKPPPQQPGP 486

Query: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRIS-SVPGTSRVEPGPRTPGTAVVDLR-- 1669
               P      A  P    G    P +     + S   PG+++  P  + PG+A    +  
Sbjct: 487  AKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTK--PPSQQPGSAKPSAQQP 544

Query: 1670 TAVKPT------PIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH 1723
            +  KP+      P+  T  G  L    V           +P           + L+  E 
Sbjct: 545  SPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEK 604

Query: 1724 TFLATATTVSITMAS------SVFMAQQKQPVVYGDPYQSRL--DFGQGGGSPVCLAQVK 1775
                T T    T+ S      +  + + K+ +      +  L  D      SP    ++K
Sbjct: 605  ANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSP--QPKLK 662

Query: 1776 QVEQAVQTAPYRSGPRGR---PREAKFARYNL-----PNQVAPLARRDVL-------ITQ 1820
                   +A  +S P+ +   P++    + +L     P +  PL ++  L         Q
Sbjct: 663  TAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQ 722

Query: 1821 MGTAQSIGLKPGPVPEPG--AEPHRATPAELRSHALPGARKPHTVVVQMGEGT------A 1872
               A S+  KP P  EP   +E  +A  A+ +    P   KP T +V     T      +
Sbjct: 723  PPEADSLS-KPAPPKEPSVPSEQDKAPVADDKPKQ-PKMVKPTTDLVSSSSATTKPDIPS 780

Query: 1873 GTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAA 1932
              V +   E+    L     +P             PF S       P P+   K ++   
Sbjct: 781  SKVQSQAEEKTTPPLKTDSAKPSQSFPPTGEKVS-PFDSKAI----PRPASDSKIISHPG 835

Query: 1933 PPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            P  +S        DP   +    +AQ  + P P  + +P P+G P
Sbjct: 836  PSSESKG--QKQVDPVQKKEEPKKAQTKMSPKP--DAKPMPKGSP 876



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 55/199 (27%), Positives = 75/199 (37%), Gaps = 15/199 (7%)

Query: 3694 KGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAA 3753
            K    +P + E   P  + +    ASDSK  S   H GP++ +SK + Q  P +Q ++  
Sbjct: 801  KPSQSFPPTGEKVSPFDSKAIPRPASDSKIIS---HPGPSS-ESKGQKQVDP-VQKKEEP 855

Query: 3754 PGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPA 3813
               Q   SP     P    S  P   +   G  +  PQQ+    + Q+QS+  +      
Sbjct: 856  KKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQS---PKPQEQSRRFSLNLGSI 912

Query: 3814 ASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAP----QQGR-APQAQ-PAPGP 3866
               P  +P     T TG     G     Q +    TA  P    Q G  AP  Q PAP  
Sbjct: 913  TDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPGPHSQSGPGAPMKQAPAPSQ 972

Query: 3867 GPAGVKAGARPGGTPGAPA 3885
             P         G  P APA
Sbjct: 973  PPTSQGPPKSTGQAPPAPA 991



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/219 (25%), Positives = 75/219 (34%), Gaps = 53/219 (24%)

Query: 521  LEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKAS 580
            L+ S   P P PPP    PP   P                   P  PLP   SP   K +
Sbjct: 2399 LDISAQPPPPPPPPPPPPPPPPPP-------------------PPPPLPPPTSP---KPT 2436

Query: 581  PLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPK----PPPETTPTPATPKVK 636
             LP K    A P+  + P     +  E    + +   P+ +     PP   P P++  + 
Sbjct: 2437 ILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPKPSS--IP 2494

Query: 637  SGV---RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSS 693
            SG+    R EP+ P     P AP          KP       + Q  +D      G+S +
Sbjct: 2495 SGLVFTHRPEPSKP-----PIAP----------KPVIPQLPTTTQKPTDIHPKPTGLSLT 2539

Query: 694  QSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMR 732
             S    +V        SA    P P SP   H   SS R
Sbjct: 2540 SSMTLNLV-------TSADYKLPSPTSPLSPHSNKSSPR 2571



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/242 (24%), Positives = 83/242 (34%), Gaps = 36/242 (14%)

Query: 1452 KPLSASDGEG-------GTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEF 1504
            KP+    G G       GTP+   +       S P     P + PT +P     +   + 
Sbjct: 217  KPIPKQQGPGRDPLQQDGTPKSISSQQPEKIKSQPPGTGKPIQGPTQTPQTDHAKLPLQR 276

Query: 1505 STQTPSPAPASDMPRS----PGAPTPS-PMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
                P    A D+ R     P  P+PS P + Q   TP +P   +    E SQ  P    
Sbjct: 277  DASRPQTKQA-DIVRGESVKPSLPSPSKPPIQQ--PTPGKPPAQQ-PGHEKSQPGP---- 328

Query: 1560 TLASDASSQTRMVHASASTSPLCS-PTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
                           S  T PL   P   +P       T PP+    P +PP        
Sbjct: 329  --------AKPPAQPSGLTKPLAQQPGTVKPPVQPPGTTKPPAQPLGPAKPPAQQTGSEK 380

Query: 1619 PSAGADGPLALY---GWGALPAENISLCRISS----VPGTSRVEPGPRTPGTAVVDLRTA 1671
            PS+   GP AL    G G  PA+     +  +     P     +PG ++P  A    +T 
Sbjct: 381  PSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAKAPGPTKTP 440

Query: 1672 VK 1673
            V+
Sbjct: 441  VQ 442



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 41/161 (25%), Positives = 52/161 (32%), Gaps = 32/161 (19%)

Query: 2201 PIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYR 2260
            P   T P+  QP +V  P+   G  +P                     P  PLGP     
Sbjct: 335  PSGLTKPLAQQPGTVKPPVQPPGTTKP---------------------PAQPLGPA---- 369

Query: 2261 YPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIK 2320
               P      S  P +E P   G  A A+ PG G    P    G A+       TP  + 
Sbjct: 370  --KPPAQQTGSEKPSSEQP---GPKALAQPPGVG--KTPAQQPGPAKPPTQQVGTPKPLA 422

Query: 2321 EAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQ 2361
            +  G  +PA   G        PG G     + G  K  A Q
Sbjct: 423  QQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQ 463



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 58/241 (24%), Positives = 86/241 (35%), Gaps = 55/241 (22%)

Query: 3673 DLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGP 3732
            D G+  +   SQ S  P++ K    G      +  PS+                ++HS P
Sbjct: 4833 DHGKSHSSQSSQQSPKPSVIKSRSHGI-----FPDPSKDMQV--------PTIEKSHSSP 4879

Query: 3733 AALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQ 3792
             + +S +E        G   + GP +SQS +S            QT  +  G  +   + 
Sbjct: 4880 GSSKSSSE--------GHLRSHGPSRSQSKTS----------VTQTHLEDAGAAIAAAEA 4921

Query: 3793 ALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA--- 3849
            A+ Q R+Q    P  R   PA S          ST +     G   +  + GS  TA   
Sbjct: 4922 AVQQLRIQPTKPPNHR---PAESSV--------STGSSGSSFGSGYSVDSEGSSSTAGET 4970

Query: 3850 ---------KAPQQGRAPQAQPAPGPGPAGVKAGAR-PGGTPGAPAGQPGADGESVFSKI 3899
                     K  Q G+ P  QP  G G A  +A  +  G    A   +   DGE +  +I
Sbjct: 4971 NLFPIPRIGKMGQNGQEPVKQPGVGVGLADTEAKTQVMGEIKIALKKEMKTDGEQLIVEI 5030

Query: 3900 L 3900
            L
Sbjct: 5031 L 5031



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 61/265 (23%), Positives = 91/265 (34%), Gaps = 70/265 (26%)

Query: 528  PTPLPPPTSQQPPVGAPHRASGTSPLKQKGP--------------QGLGQP------SGP 567
            P PLPPPTS +P +    + +  SP+    P              +  G P      + P
Sbjct: 2424 PPPLPPPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP 2483

Query: 568  LPAKASPLSTKAS------PLPSKASPQAKPLRASEPSKT--PSSVQEKKT--------- 610
             P    P S  +       P PSK     KP+    P+ T  P+ +  K T         
Sbjct: 2484 PPVPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT 2543

Query: 611  -RVPTKAE---PMPKPPPETTPTPATPKVKSGVRR--------AEPATPVVKAVPEA--- 655
              + T A+   P P  P       ++P+    +          +EP TP   +  +A   
Sbjct: 2544 LNLVTSADYKLPSPTSPLSPHSNKSSPRFSKSLTETYVVITLPSEPGTPTDSSASQAITS 2603

Query: 656  -PKGGEAEDLVG-KPYSQ-----DASRSPQSLSDTGYSSDGI-----------SSSQSEI 697
             P G  ++DLV  +P         A   P S   T Y S  +           SS Q+  
Sbjct: 2604 WPLGSPSKDLVSVEPVFSVVPPVTAVEIPISSEQTFYISGALQTFSATPVTAPSSFQAAP 2663

Query: 698  TGVVQQEVEQLDSAGVTGPHPPSPS 722
            T V Q    ++    V+     +PS
Sbjct: 2664 TSVTQFLTTEVSKTEVSATRSTAPS 2688



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 16/128 (12%)

Query: 1490 TFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTP------SPMVAQGT--QTPHRPS 1541
            T+  G +G +  A+  TQ+P    A+  P+    PTP      S + A  T    P  P 
Sbjct: 3559 TYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADSTVQLAPSPPK 3618

Query: 1542 TPRLVWQESSQEAPFMVITLA--------SDASSQTRMVHASASTSPLCSPTETQPTTHG 1593
            +P++++   S  +P   +  A         D  S  +++H   +  P  SP   +     
Sbjct: 3619 SPKVLYSPISPLSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPASPKTAKMMQRS 3678

Query: 1594 YSQTTPPS 1601
             S   P S
Sbjct: 3679 MSDPKPLS 3686



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 62/266 (23%), Positives = 93/266 (34%), Gaps = 42/266 (15%)

Query: 2115 HGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQG 2174
            H     GP     QP    GL+ P   +  +PG +  P  P G   P      GPA    
Sbjct: 321  HEKSQPGPAKPPAQPS---GLTKP---LAQQPGTVKPPVQPPGTTKPP-AQPLGPAKPPA 373

Query: 2175 TAVRQLLPSTA-----TVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG-GMYRPY 2228
                   PS+       +    G+  +    P  A  P  TQ     +P+ +  G+  P 
Sbjct: 374  QQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP--TQQVGTPKPLAQQPGLQSPA 431

Query: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRY---PAPSRFPIASSVPPAEGPVYLGKP 2285
             + G T  P+       + A +   G T   +      PS+ P  +  PP +       P
Sbjct: 432  KAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPSQLPGPAKPPPQQ-------P 484

Query: 2286 AAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGG 2345
              AK P       P+ P G+A+    P+  P + K     P PA  + Q+P +   P   
Sbjct: 485  GPAKPP-------PQQP-GSAKP---PSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS-- 531

Query: 2346 SGALSRPGFEKEEASQEERQRKQQEQ 2371
                 +PG  K  A Q    +   +Q
Sbjct: 532  ----QQPGSAKPSAQQPSPAKPSAQQ 553



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 38/147 (25%), Positives = 51/147 (34%), Gaps = 24/147 (16%)

Query: 1485 PSESPTFSPGKMGPR-----ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR 1539
            PS SP+ S     PR     ++ + S Q P P P    P  P  P P P +      P  
Sbjct: 2377 PSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPL----PPPTS 2432

Query: 1540 PSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTS-PLCSPTETQPTTHGYSQTT 1598
            P    L  ++ +  +P    T   DA +         S   P+     T P         
Sbjct: 2433 PKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAP------PPV 2486

Query: 1599 PPSVSQLP--------PEPPGPPGFPR 1617
            PP  S +P        PEP  PP  P+
Sbjct: 2487 PPKPSSIPSGLVFTHRPEPSKPPIAPK 2513



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 17/30 (56%), Positives = 21/30 (70%), Gaps = 2/30 (6%)

Query: 3888 PGADGE--SVFSKILPGGAAEQAGKLTEAV 3915
            PG  GE  +  +KILPGG+AEQ GKL E +
Sbjct: 4524 PGHSGEIGAYIAKILPGGSAEQTGKLMEGM 4553



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 74/330 (22%), Positives = 121/330 (36%), Gaps = 39/330 (11%)

Query: 2931 TTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESL 2990
            + VP  +  +   +  DL + E +  K  KK+       + ++A     EL   + K SL
Sbjct: 2276 SVVPKPEGPVADTVSTDLLISEKDPVKKAKKETGNGIILEVLEAYRDKKELEAERTKSSL 2335

Query: 2991 AKDRGGRDYPPLRGLG-EHRDYLSDSELNQLRLQGCTTPAGQFVD-FPATAAAPATPSGP 3048
            ++     D+PP   +    ++ LS +        G   PA Q     P+ ++ PA P   
Sbjct: 2336 SETVF--DHPPSSVIALPMKEQLSTTYFTSGETFGQEKPASQLPSGSPSVSSLPAKP--- 2390

Query: 3049 TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPN 3108
                +P F+  +   SA             Q P  P P   P P  PP    P  P    
Sbjct: 2391 ----RPFFRSSSLDISA-------------QPPPPPPPPPPPPPPPPPPPPPPLPPPTSP 2433

Query: 3109 QQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV 3168
            +    P       +P+ TT + LF    D+   L+    T++        T     A P 
Sbjct: 2434 KPTILPKKKLTVASPV-TTATPLF----DAVTTLE---TTAVLRSNGLPVTRICTTAPPP 2485

Query: 3169 VP--MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQN 3226
            VP   SS PS   ++     S       P +P+     + +Q P   +P  +   SL  +
Sbjct: 2486 VPPKPSSIPSGLVFTHRPEPSKPPIAPKPVIPQL---PTTTQKPTDIHPKPTG-LSLTSS 2541

Query: 3227 VPRNYVMIDDISELTKDSTSTAPDSQRLEP 3256
            +  N V   D  +L   ++  +P S +  P
Sbjct: 2542 MTLNLVTSADY-KLPSPTSPLSPHSNKSSP 2570


>gi|163965366 nascent polypeptide-associated complex alpha subunit
            isoform a [Homo sapiens]
          Length = 2078

 Score =  114 bits (285), Expect = 2e-24
 Identities = 181/683 (26%), Positives = 234/683 (34%), Gaps = 103/683 (15%)

Query: 11   AGDGPLPPGG-AGPGPGPGPGPGAGKPPSAPAGGGQLPA-AGAARSTAV-PPVPGPGPGP 67
            A   P P GG A P P   P P A  PPS P GG   P+  GA    AV PP P   P  
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPS-PKGGPATPSPKGAPTPPAVTPPSPKGSPAA 1025

Query: 68   GPGPGPGSTSRRLDPKEPLGNQRAASPTPKQA----SATTPGHES-------------PR 110
             P P   ST     P  P G+  AA+P PK A    +AT P  +              P 
Sbjct: 1026 TPFPKGASTPPAATPPSPKGSP-AATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPA 1084

Query: 111  ETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLC 170
             T      G     P+      + T  S +    +P     PT+P + P       +T  
Sbjct: 1085 ATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144

Query: 171  PICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDM 230
            P    +   +TP  P     T             P P               + A     
Sbjct: 1145 PKGAPTTPAATPPSPKGGLAT-------------PPP---------------KGAPTTPA 1176

Query: 231  TTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGP-QPGSRQAETARATSVPG 289
             T P  K      SP  +P    A  P  K         G P  P +         + P 
Sbjct: 1177 ATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPS 1236

Query: 290  PAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPA-KSATAVPAGLGATEQTQEGLTG 348
            P  A   P     SP+    T P    P PPA   P+ K   A P   GA          
Sbjct: 1237 PKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPS 1296

Query: 349  KLFGLGASLLTQASTLMSVQPEADTQGQPA--PSKGTPKIVFNDASKEAGPKPLGSGPGP 406
               G   S    A T  +  P +  +G P   P KG P            P P G+   P
Sbjct: 1297 PKGGPATSPPKGAPTPPAATPPS-PKGSPGTPPPKGAP-----TPPAVTPPSPKGTPTLP 1350

Query: 407  GPAPGAK---TEPGARMGPGSGPGALPKTGG-----TTSPKHGRAEHQAASKAAAKPKTM 458
               P +K   T P ++ GP + P A P   G       SPK G         A   PK  
Sbjct: 1351 ATTPSSKGGPTTPSSKEGP-TPPAATPSHKGGPAMTPPSPKRG--------PAIPSPKGD 1401

Query: 459  PKERAICPLCQAELNVGSKSPANYNTCT-TCRLQVCNLCGFNPTPHLVEKTEWLCLNCQT 517
            P   A+ PL         K+PA   T          +L     TP  ++K        + 
Sbjct: 1402 PTSPAVIPLSP------KKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP-KG 1454

Query: 518  KRLLEGSLGEPT--PLPPPTSQQPPVGAPHR-ASGTSPLKQKG-PQGLGQPSGPLPAKAS 573
                  S G+PT   + PP+ ++PP  AP + A+ +SP K    P  +G P+ P    +S
Sbjct: 1455 GPATPSSKGDPTLPAVTPPSPKEPP--APKQVATSSSPKKAPATPAPMGAPTLPAVIPSS 1512

Query: 574  PLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
            P    A+P  S+  P A P       KTP+++  K+  +P     M  P P+ TP   TP
Sbjct: 1513 PKEVPATP-SSRRDPIA-PTATLLSKKTPATLAPKEALIP---PAMTVPSPKKTPAIPTP 1567

Query: 634  KVKSGVRRAEPATPVVKAVPEAP 656
            K         PATP  K     P
Sbjct: 1568 K-------EAPATPSSKEASSPP 1583



 Score =  107 bits (268), Expect = 2e-22
 Identities = 193/789 (24%), Positives = 265/789 (33%), Gaps = 99/789 (12%)

Query: 11   AGDGPLPPGGAGPGPGPG-PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGP 69
            A   P P GG    P  G P   A  PPS   G    P  GA  + A  P    G    P
Sbjct: 1107 AATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATP 1166

Query: 70   GPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTL 129
             P    T+    P  P G    A+P+PK A  T      P  T      G     P+   
Sbjct: 1167 PPKGAPTTPAATPPSPKGG--LATPSPKGAPTT------PAATPPSPKGGLATPSPKGAP 1218

Query: 130  QVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNT 189
               + T  S +    +P     PT+P + P       +T  P    +   +TP       
Sbjct: 1219 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL 1278

Query: 190  CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249
             T  H          PNP +                 G   T+ P+        +P  SP
Sbjct: 1279 ATPPHKGA-------PNPAVVTPPS----------PKGGPATSPPKGAPTPPAATPP-SP 1320

Query: 250  AHSP-AKQPLGKPDQERSRGP---GGP-----QPGSRQAETARATSVPGPAQAAAPPEVG 300
              SP    P G P       P   G P      P S+   T  ++       AA P   G
Sbjct: 1321 KGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKG 1380

Query: 301  RVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFG-LGASLLT 359
              +  PP P K   A P P             P    AT  T+EG      G L    +T
Sbjct: 1381 GPAMTPPSP-KRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVT 1439

Query: 360  QASTLMSVQPEADTQGQPAP-SKGTPKI--VFNDASKE-AGPKPLGSGPGPGPAPGAKTE 415
              S   +    A   G   P SKG P +  V   + KE   PK + +   P  AP     
Sbjct: 1440 PVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAP 1499

Query: 416  PGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM-PKERAICPLCQAELNV 474
             GA   P   P +  +   T S +       A   +   P T+ PKE  I P        
Sbjct: 1500 MGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV---- 1555

Query: 475  GSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP---- 530
               SP       T +           TP   E +    +   T +      G P+P    
Sbjct: 1556 --PSPKKTPAIPTPKEAPA-------TPSSKEASSPPAVTPSTYK------GAPSPKELL 1600

Query: 531  LPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQA 590
            +PP  +   P  AP   + T P  +KG      P+ P P K +P S   +P   K SP +
Sbjct: 1601 IPPAVTSPSPKEAPTPPAVTPPSPEKG------PATPAP-KGTPTSPPVTPSSLKDSPTS 1653

Query: 591  KPLRASEPSKTPSSVQEKKTRVPTKAEP------MPKPPPETTPTPATPKVKSGVRRAEP 644
                AS   K  ++V +    +P K  P      +  P PE+TP    P  K    +   
Sbjct: 1654 P---ASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSS 1710

Query: 645  AT-PVVKAVPEAPKGGEAEDL---------VGKPYSQDASRSPQSLSDTGYSSDGISSSQ 694
            AT P +   P A  G +             V K  S+ A     S S  G  +   S + 
Sbjct: 1711 ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGPLAPPESKAS 1770

Query: 695  SEITGVVQQEV-EQLDSAGVT-GPHPP-----SPSEIHKVGSSMRPLLQAQGLAPSERSK 747
            + +T    ++V  + +SA V+  P PP     +PS +  +    + L  + GL     SK
Sbjct: 1771 TPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSK 1830

Query: 748  PLSSGTGEE 756
            PL+    +E
Sbjct: 1831 PLAPADEDE 1839



 Score =  105 bits (263), Expect = 7e-22
 Identities = 200/806 (24%), Positives = 264/806 (32%), Gaps = 125/806 (15%)

Query: 16   LPPGGAGPGPGPGPG--------PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGP-G 66
            LPP G  PG     G        P A  P   P       A  +++ T       P P G
Sbjct: 739  LPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLG 798

Query: 67   PGPGPG---PGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEAD 123
                P    P +      P  P+GN   +SP     ++  P +    +     PA   + 
Sbjct: 799  VSVSPQTKRPPTKKGSAGPDTPIGN--LSSPVSPVEASFLPENSLSFQGSKDSPATTHSP 856

Query: 124  GPRRTLQVDSRTQRSGRSPSVSPDRGS-TPTSPYSV---PQIAPLPSSTLCPICKTSDLT 179
             P               SP  +P   + TP SP  V   P+  P PS    P  K    T
Sbjct: 857  TPP--------------SPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPAT 902

Query: 180  STPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQ 239
              P Q    + T    K             T   + +  +   + A      T P  K  
Sbjct: 903  PAPKQAPALSMTSSSPK---------KARATPAPKGIPASPSPKGAPTPPAATPPSPKGG 953

Query: 240  QQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARA-TSVPGPAQAAAPPE 298
                SP  +P    A  P  K         G P P +    + +   + P P  A  PP 
Sbjct: 954  PATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPA 1013

Query: 299  VGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLL 358
            V      PP P     A P P     P  +    P G  A     +G             
Sbjct: 1014 V-----TPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAP----------T 1058

Query: 359  TQASTLMSVQPEADT---QGQPAPSKGTPKIVFNDA---SKEAGPKPLGSGPGPGPAPGA 412
            T A+TL S +    T   +G P P   TP          S +  P P  + P P P  G 
Sbjct: 1059 TPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATP-PSPKGGL 1117

Query: 413  KTEP--GARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAK-------PKTMPKERA 463
             T P  GA   P + P + PK G  T P  G     AA+  + K       PK  P   A
Sbjct: 1118 ATPPHKGAPTTPAATPPS-PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPA 1176

Query: 464  ICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCG--FNPTPHLVEKTEWLCLNCQTKRLL 521
              P        G  +P+     TT      +  G    P+P     T        T    
Sbjct: 1177 ATP---PSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTP-----AATPPSP 1228

Query: 522  EGSLGEPTPLPPPTSQQ-------------PPVGAPHRASGTSPLKQKGPQGLGQPSGPL 568
            +G L  P+P   PT+               PP GAP   + T P  + G         P 
Sbjct: 1229 KGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPN 1288

Query: 569  PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMP----KPPP 624
            PA  +P S K  P  S   P+  P   + P+ TP S +      P K  P P     P P
Sbjct: 1289 PAVVTPPSPKGGPATS--PPKGAP---TPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSP 1343

Query: 625  ETTPT-PA-TPKVKSGVRRAEPATPVVKAVPEAP------KGGEAEDLVGKPYSQDASRS 676
            + TPT PA TP  K G     P TP  K  P  P      KGG A      P    A  S
Sbjct: 1344 KGTPTLPATTPSSKGG-----PTTPSSKEGPTPPAATPSHKGGPAM-TPPSPKRGPAIPS 1397

Query: 677  PQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQ 736
            P+    T  +   +S  ++  T V  +E     S G   P   +P  + K  ++  P  +
Sbjct: 1398 PKG-DPTSPAVIPLSPKKAPATPVT-REGAATPSKGDLTPPAVTPVSLKKAPATSAP--K 1453

Query: 737  AQGLAPSERSKP-LSSGTGEEQKQRP 761
                 PS +  P L + T    K+ P
Sbjct: 1454 GGPATPSSKGDPTLPAVTPPSPKEPP 1479



 Score = 96.7 bits (239), Expect = 4e-19
 Identities = 345/1577 (21%), Positives = 504/1577 (31%), Gaps = 268/1577 (16%)

Query: 225  ALGMDMTTAPRSKSQQQLHSPA-----LSPAHSP---AKQPLGKPDQERSRGPGGPQPGS 276
            ALG    T P   S      P       SP  SP   A  PL  P  + S G   P   +
Sbjct: 37   ALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTA 96

Query: 277  RQAETARATSVPGPAQAAAPPEVGRVSPQ--PPQPTKPSTAEPRPPAGEAP---AKSATA 331
             +A T     +  P   AA   +   SP   P     PS++ P      AP    KS+  
Sbjct: 97   PEAPTFLPNLIGPPISPAA---LALASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAF 153

Query: 332  VPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDA 391
             P  L +        +G +  L A +                    APS+  PK   N  
Sbjct: 154  PPNLLTSPPSVAVAESGSVITLSAPI--------------------APSE--PKTNLNKV 191

Query: 392  SKEAGPKPLGSGPGPGPAPGAKTEPGARMGP----GSGPGALPKTGGTT-----SPKHGR 442
              E  P P G+   P P     T P   + P     SG  +LP+T  TT     SP+   
Sbjct: 192  PSEVVPNPKGT---PSPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKD 248

Query: 443  AEHQAASKAAAKPKTMPKERAICP-------------LCQAELNVGSKSPANYNTCTTCR 489
                +   +   P ++  +  + P             +  ++   G  +P ++       
Sbjct: 249  TTISSVLISPQNPGSLSLKGPVSPPAALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSH 308

Query: 490  LQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLE---GSLGEPTP-----LPPPTSQQPPV 541
            L   +   F     L+ +T    L+  T + +     S G   P     +PP  S+   V
Sbjct: 309  LAPLHQSSFGSV-QLLGQTGPSALSDPTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVV 367

Query: 542  GAPHRASGT-SPLKQKGPQGLGQ----PSGPLPAKASPLSTKASPLPSKASPQAK---PL 593
             A   A    +P   KGP  +      PSG L    S   +  + L  K+SP A    PL
Sbjct: 368  PATVAAFPVVAPSVDKGPSTISSITCSPSGSLNVATSFSLSPTTSLILKSSPNATYHYPL 427

Query: 594  RASEP----SKTPSSVQEKKT---------RVPTKAEPMPKPPPETTPTPATPK--VKSG 638
             A  P      TP  V    T          V T   P     P +   P +P   V + 
Sbjct: 428  VAQMPVSSVGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIEPTSPAALVMAP 487

Query: 639  VRRAEPATPVVKA--VPEAPKGGEAEDLVGKPYS--------QDASRSPQSLSDTGYSSD 688
            V   EP+T V     +P +P   + EDL   P S        +D    P SL    +S  
Sbjct: 488  VAPKEPSTQVATTLRIPVSPPLPDPEDLKNLPSSVLVKFPTQKDLQTVPASLEGAPFSP- 546

Query: 689  GISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKP 748
                +Q+ +T      V  L  A        SPS      S   PL     LA     +P
Sbjct: 547  ----AQAGLTTKKDPTVLPLVQAAPKN----SPSFQSTSSSPEIPLSPEATLAKKSLGEP 598

Query: 749  LSSGTGEEQKQRPHSLSITPEAFDSDEEL--EDILEEDEDSAEWRRRREQQDTA-----E 801
            L  G       +P S   +P   +S   +   D     + +    +      T      E
Sbjct: 599  LPIG-------KPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLE 651

Query: 802  SSDDFG-----SQLRHDYVEDSS---EGGLSPLPPQPPARAAELTDEDFMRRQILEMSAE 853
            S+D  G     ++    Y   +S   EG +S  P   P +   LT         L  +A 
Sbjct: 652  SADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLP------LVPTAS 705

Query: 854  EDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGG 913
            E+         +   LA        P+  P PS  PA  P      +  +    L P   
Sbjct: 706  ENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVAS 765

Query: 914  SAEA--TDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSP 971
            S +   T+ SG               +  S G    L   P P            ++ SP
Sbjct: 766  SPKECPTEDSGASA------------TASSKGTLTYLADSPSPL----------GVSVSP 803

Query: 972  EDRSRGEHSSTLPASTP--SYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRS 1029
            + +       +    TP  + +S  SP   S L E+S S        + +K      H  
Sbjct: 804  QTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLS-------FQGSKDSPATTHSP 856

Query: 1030 HGPLLPTIEDSSEEEELREEEELLREQEKMRE------VEQQRIRSTARKTRRDKEELRA 1083
              P        S    L  +   L  +E            ++   + A K         +
Sbjct: 857  TPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSS 916

Query: 1084 QRRRERSKTPPSNL--SPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDG 1141
              ++ R+   P  +  SP    +PT         +    +   +++P+P   +      G
Sbjct: 917  SPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSP-KG 975

Query: 1142 GPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPS-SGRPLKSAEEAYEEMMRKAELLQR 1200
            GP+     G+    PT  +   P+  P G   TPS  G P   A                
Sbjct: 976  GPATPSPKGA----PTPPAATPPS--PKGGPATPSPKGAPTPPA---------------- 1013

Query: 1201 QQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEI 1260
                      P G P+    P+G  +         +   AA P  +G P +  A +    
Sbjct: 1014 -----VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSP- 1067

Query: 1261 LQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAP 1320
             +   +   ++ A +   A     K      + + A M P      P     +P    AP
Sbjct: 1068 -KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAP 1126

Query: 1321 VSFSTPTSSDSS--GGRVIPDVRVTQHFAKETQDPLKLHSSPAS-PSSASKEIGMPFSQG 1377
               +TP ++  S  GG   P              P    ++PA+ P S    +  P  +G
Sbjct: 1127 ---TTPAATPPSPKGGLATPP-------------PKGAPTTPAATPPSPKGGLATPPPKG 1170

Query: 1378 -PGTPATTA-------VAPCPAGLPRG-YMTPASPAGSERSPSPSSTAHSYGHSPTTANY 1428
             P TPA T          P P G P     TP SP G   +PSP     +   +P +   
Sbjct: 1171 APTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKG 1230

Query: 1429 GSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSES 1488
            G  T     AP+  AA   + +  P +       TP  +   S     + P    +P+ +
Sbjct: 1231 GLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPA 1290

Query: 1489 PTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQ 1548
                P   G  AT+          P    P  P A  PSP  + GT  P    TP  V  
Sbjct: 1291 VVTPPSPKGGPATS----------PPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTP 1340

Query: 1549 ESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLP-- 1606
             S +  P +  T  S     T        T P  +P+       G    TPPS  + P  
Sbjct: 1341 PSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSH-----KGGPAMTPPSPKRGPAI 1395

Query: 1607 PEPPGPPGFPRV----PSAGADGPLALYG-----WGALPAENISLCRISSVPGTSRVEPG 1657
            P P G P  P V    P      P+   G      G L    ++   +   P TS  + G
Sbjct: 1396 PSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGG 1455

Query: 1658 PRTPGTAVVDLRTAVKP 1674
            P TP +       AV P
Sbjct: 1456 PATPSSKGDPTLPAVTP 1472



 Score = 89.0 bits (219), Expect = 9e-17
 Identities = 175/753 (23%), Positives = 241/753 (32%), Gaps = 133/753 (17%)

Query: 94   PTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPT 153
            P  +    T P   +  E     P+ Q    P  TL +     +S  SPS+ P    TP 
Sbjct: 689  PVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP--AGTPP 746

Query: 154  SPYSVPQIAPLPSSTLCPI------CKTSD---------------LTSTPSQPNFNTCTQ 192
                V  I+   +S L P+      C T D               L  +PS    +   Q
Sbjct: 747  GTKKVDGIS--HTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQ 804

Query: 193  CHNKVCNQCGFNPNPHLTQVKEWLC---------LNCQMQRALGMDMTT-APRSKSQQQL 242
                   +    P+  +  +   +           +   Q +     TT +P   S +  
Sbjct: 805  TKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA 864

Query: 243  HSPA-----------LSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
             +P+           L P  +P    +  P  +   GP  P P    A  +  +S P  A
Sbjct: 865  PTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPK--EGPATPAPKQAPA-LSMTSSSPKKA 921

Query: 292  QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLF 351
            +A   P+    SP P     P  A P  P G     S    P    AT  + +G      
Sbjct: 922  RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG------ 975

Query: 352  GLGASLLTQASTLMSVQPEADTQGQPAPS-KG--TPKIVFNDASK---EAGPKPLGSGPG 405
            G        A T  +  P +   G   PS KG  TP  V   + K    A P P G+   
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTP 1035

Query: 406  PGPAP--------------GAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKA 451
            P   P              GA T P A +    G  A P   G  +P            A
Sbjct: 1036 PAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPA 1095

Query: 452  AAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWL 511
               PK  P   A  P        G  +P +    TT      +  G   TP         
Sbjct: 1096 TPSPKGAPMPPAATP---PSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP-------- 1144

Query: 512  CLNCQTKRLLEGSLGEPTPLPPP----TSQQPPVGAPHRASGTSPLKQKG---PQGLGQP 564
                      +G+   P   PP      +  PP GAP   + T P  + G   P   G P
Sbjct: 1145 ---------PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAP 1195

Query: 565  SGPLPAKASPLSTKASPLPSKA--SPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPK- 621
            + P     SP    A+P P  A  +P A P        TPS      T  P    P PK 
Sbjct: 1196 TTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTT--PAATPPSPKG 1253

Query: 622  ----PPPETTPTP---ATPKVKSGV----RRAEPATPVVKAVPEAPKGGEAEDLVGKPYS 670
                PPP+  PTP     P +K G+     +  P   VV   P +PKGG A        +
Sbjct: 1254 GPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVV--TPPSPKGGPATSPPKGAPT 1311

Query: 671  QDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDS------------AGVTGPHP 718
              A+  P      G      + +   +T    +    L +            +   GP P
Sbjct: 1312 PPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTP 1371

Query: 719  PSPSEIHKVGSSMRPLLQAQGLA-PSERSKPLS 750
            P+ +  HK G +M P    +G A PS +  P S
Sbjct: 1372 PAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404



 Score = 85.1 bits (209), Expect = 1e-15
 Identities = 125/491 (25%), Positives = 181/491 (36%), Gaps = 59/491 (12%)

Query: 1204 QAAGARGPHGGPS------QPTGPRGLGSFEYQDTTDREYGQAAQPA-AEGTPASLGAAV 1256
            +A     P GGP+       PT P        +    ++   ++ P  A  TPA +GA  
Sbjct: 1445 KAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPT 1504

Query: 1257 YEEILQTSQSIVRMRQASSRDLAFAED---KKKEKQFLNAESAYMDPMKQNGGPLTPGTS 1313
               ++ +S   V    +S RD          KK    L  + A + P      P      
Sbjct: 1505 LPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAI 1564

Query: 1314 PTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMP 1373
            PT   AP   +TP+S ++S         VT    K    P +L   PA  S + KE   P
Sbjct: 1565 PTPKEAP---ATPSSKEASSPPA-----VTPSTYKGAPSPKELLIPPAVTSPSPKEAPTP 1616

Query: 1374 FSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSP-SPSSTAHSYGHSPTTANYGSQT 1432
             +  P +P      P P G P     P +P+  + SP SP+S     G +   A+ G   
Sbjct: 1617 PAVTPPSPEKGPATPAPKGTPTS--PPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPA 1674

Query: 1433 EDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFS 1492
            +  P A   +  A        ++A   +G  PQ  ++    +++SPP+ P      P+  
Sbjct: 1675 KKGPTALKEVLVAPAPESTPIITAPTRKG--PQTKKS----SATSPPICPD-----PSAK 1723

Query: 1493 PGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQ 1552
             G  GP +T        +PAP   + +       S   A+G    H P  P L   ES  
Sbjct: 1724 NGSKGPLSTV-------APAPLLPVQKD------SSKTAKGKDASHSPKGP-LAPPESKA 1769

Query: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
              P     L + A  +      SAS S   SP  + P       T PP    LP  P   
Sbjct: 1770 STP-----LTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPPKQQFLPSSPGLV 1824

Query: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAV 1672
               P  P A AD    L     +P E IS      VP  S +   P TP +A + + T  
Sbjct: 1825 LESPSKPLAPADEDELL---PLIPPEPIS----GGVPFQSVLVNMP-TPKSAGIPVPTPS 1876

Query: 1673 KPTPIILTDQG 1683
               P+   ++G
Sbjct: 1877 AKQPVTKNNKG 1887



 Score = 84.7 bits (208), Expect = 2e-15
 Identities = 186/824 (22%), Positives = 267/824 (32%), Gaps = 108/824 (13%)

Query: 1193 RKAELLQRQQGQAAGARGPHGGPSQPTGPRGL----GSFEYQDTTDREYGQAAQPAAEGT 1248
            +K + +      A  A  P   P++ +G        G+  Y   +    G +  P  +  
Sbjct: 749  KKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRP 808

Query: 1249 PASLGAAVYEEILQTSQSIVRMRQAS---SRDLAFAEDKKKEKQFLNAESAYMDPMKQNG 1305
            P   G+A  +  +    S V   +AS      L+F   K        A +    P    G
Sbjct: 809  PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSP-----ATTHSPTPPSPKG 863

Query: 1306 GPLTPGT----SPTQLAAPVSFSTPTSSDSS-----GGRVIPDVRVTQHFAKETQDPLKL 1356
             P TP      SP  +  P    TPT S  +      G   P  +     +  +  P K 
Sbjct: 864  AP-TPSAVTPLSPKGVTLPPK-ETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKA 921

Query: 1357 HSSPAS---PSSAS-KEIGMPFSQGPGTPATTAVAPCPAGLPRG-YMTPASPAGSERSPS 1411
             ++PA    P+S S K    P +  P +P      P P   P     TP SP G   +PS
Sbjct: 922  RATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPS 981

Query: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYS 1471
            P         +P +   G  T     AP+  A         P S       TP P  A  
Sbjct: 982  PKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVT-------PPSPKGSPAATPFPKGA-- 1032

Query: 1472 YFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVA 1531
               S+ P  +P SP  SP  +P   G   T   +  +P   PA+  P   GAPTP    A
Sbjct: 1033 ---STPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPAT--PSLKGAPTPP--AA 1085

Query: 1532 QGTQTPHRPSTPRLVWQESSQEAPFM-VITLASDASSQTRMVHASASTSPLCSPTETQPT 1590
                    P+TP      S + AP     T  S         H  A T+P  +P    P+
Sbjct: 1086 TPPSPKGGPATP------SPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATP----PS 1135

Query: 1591 THGYSQTTPP-----SVSQLPPEPPG------PPGFPRVPSAGADGPLALYGWGALPAEN 1639
              G   T PP     + +  PP P G      P G P  P+A    P    G  A P+  
Sbjct: 1136 PKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPK---GGLATPSPK 1192

Query: 1640 ISLCRISSVPGTSR---VEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKY 1696
             +    ++ P + +     P P+   T       + K      + +G   T  A      
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252

Query: 1697 GLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQ 1756
            G    P P    T                 AT  ++   +A+         P   G P  
Sbjct: 1253 GGPATPPPKGAPTPPA--------------ATPPSLKGGLAT---------PPHKGAPNP 1289

Query: 1757 SRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLPNQVAPLARRDV 1816
            + +      G P              T P    P+G P          P  V P + +  
Sbjct: 1290 AVVTPPSPKGGPATSPPKGAPTPPAATPP---SPKGSPGTPPPKGAPTPPAVTPPSPKGT 1346

Query: 1817 LITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHAL--PGARKPHTVVVQMGEGTAGT 1874
                  T  S G    P  + G  P  ATP+     A+  P  ++   +    G+ T+  
Sbjct: 1347 PTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 1875 VTTLLPEE-PAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAP 1933
            V  L P++ PA  +   G    S+          P  +  +    PA S P+   A  + 
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTP-----PAVTPVSLKKAPATSAPKGGPATPSS 1461

Query: 1934 PGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
             G  + P   P  P P EPP  +              P P G P
Sbjct: 1462 KGDPTLPAVTP--PSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503



 Score = 83.2 bits (204), Expect = 5e-15
 Identities = 180/782 (23%), Positives = 277/782 (35%), Gaps = 135/782 (17%)

Query: 15   PLPPGGAGPGP--GPGPGPGAGKP------PSAPAGGGQLPAAG----------AARSTA 56
            P PP    P P   PG  P  G P      P +P G   LPA            +++   
Sbjct: 1310 PTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGP 1369

Query: 57   VPPVPGPGPGPGPGPGPGSTSR-------RLDPKE----PLGNQRA-ASPTPKQASAT-- 102
             PP   P    GP   P S  R       + DP      PL  ++A A+P  ++ +AT  
Sbjct: 1370 TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPS 1429

Query: 103  ----TPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPS----VSPDRGSTPTS 154
                TP   +P   +          GP         T  +   PS     +P + +T +S
Sbjct: 1430 KGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSS 1489

Query: 155  PYSVPQI-APLPSSTLCPICKTS--DLTSTPS---QPNFNTCTQCHNKVCNQCGFNPNPH 208
            P   P   AP+ + TL  +  +S  ++ +TPS    P   T T    K          P 
Sbjct: 1490 PKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKK---------TPA 1540

Query: 209  LTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRG 268
                KE          AL     T P  K    + +P  +PA   +K+    P    S  
Sbjct: 1541 TLAPKE----------ALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTY 1590

Query: 269  PGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTK-PSTAEPR-----PPAG 322
             G P P  ++     A + P P +A  PP V      PP P K P+T  P+     PP  
Sbjct: 1591 KGAPSP--KELLIPPAVTSPSPKEAPTPPAV-----TPPSPEKGPATPAPKGTPTSPPVT 1643

Query: 323  EAPAKSATAVPAG----LGAT-EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP 377
             +  K +   PA     +GAT  Q  +GL  K    G + L +   L++  PE+ T    
Sbjct: 1644 PSSLKDSPTSPASVTCKMGATVPQASKGLPAK---KGPTALKE--VLVAPAPES-TPIIT 1697

Query: 378  APSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTS 437
            AP++  P+            K   + P   P P AK      +   +    LP    ++ 
Sbjct: 1698 APTRKGPQT----------KKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747

Query: 438  PKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCG 497
               G+     AS +   P   P+ +A  PL  A        P + +        V     
Sbjct: 1748 TAKGK----DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803

Query: 498  FNPTPHLVEKTEW------LCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS 551
             +P P L  K ++      L L   +K L      E  PL PP  +    G P +   + 
Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPP--EPISGGVPFQ---SV 1858

Query: 552  PLKQKGPQGLGQPSGPLPAKASPL--STKASPLPSKASPQAKPLRASEPSKTPSSVQEKK 609
             +    P+  G P  P P+   P+  + K S   S +      L   + ++  +   +  
Sbjct: 1859 LVNMPTPKSAGIPV-PTPSAKQPVTKNNKGSGTESDSDESVPELEEQDSTQATTQQAQLA 1917

Query: 610  TRVPTKAEPMPKPPPETTPTPATPKV-KSGVRRAEPATPV----------VKAVPEAPKG 658
                   EP+ K     +   A   + K G+R+    T V          V   P+  K 
Sbjct: 1918 AAAEIDEEPVSKAKQSRSEKKARKAMSKLGLRQVTGVTRVTIRKSKNILFVITKPDVYKS 1977

Query: 659  GEAEDLV--GKPYSQDASRSPQSLSDTGYSSDGISSS---QSEITGVVQQ--EVEQLDSA 711
              ++  +  G+   +D S+  Q  +   +   G + S   ++  T  VQ+  E E++D  
Sbjct: 1978 PASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGEAVSNIQENTQTPTVQEESEEEEVDET 2037

Query: 712  GV 713
            GV
Sbjct: 2038 GV 2039



 Score = 63.9 bits (154), Expect = 3e-09
 Identities = 59/209 (28%), Positives = 75/209 (35%), Gaps = 23/209 (11%)

Query: 3685 PSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAAL--QSKAEPQ 3742
            P++ P  PK G P  PS      P  A+        +    + A + PA      K  P 
Sbjct: 966  PAATPPSPKGG-PATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPA 1024

Query: 3743 AQPQLQGRQAAPG---PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARL 3799
            A P  +G    P    P    SP++  +P GA +    T    +G    P   +L  A  
Sbjct: 1025 ATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKG---GPATPSLKGAPT 1081

Query: 3800 QQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQ 3859
               + P +    PA   P G P P    AT P P G           G A  P +G AP 
Sbjct: 1082 PPAATPPSPKGGPATPSPKGAPMP--PAATPPSPKG-----------GLATPPHKG-APT 1127

Query: 3860 AQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
               A  P P G  A   P G P  PA  P
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATP 1156



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 197/883 (22%), Positives = 293/883 (33%), Gaps = 119/883 (13%)

Query: 3026 TTPAG-QFVDFPATAAAPATPSGPTAFQQPRFQPP-APQYSAGSGGPTQNGFPAHQAPTY 3083
            T PA  +   F    A   T   PT     +  P  +P + + S  P     P     T 
Sbjct: 534  TVPASLEGAPFSPAQAGLTTKKDPTVLPLVQAAPKNSPSFQSTSSSPE---IPLSPEATL 590

Query: 3084 PGPST-YPAPAFPPGASYPAEPGLPNQQAFRPTGHYAG-QTPMPTTQSTLFPVPADSRAP 3141
               S   P P   P +S  +  G+ +  +   T  YAG  +  P  +S+L   P  +  P
Sbjct: 591  AKKSLGEPLPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLI-TPTVAAFP 649

Query: 3142 LQKPRQTSLADLEQKVPTNYEVIASPVVP--MSSAPSETSYSGPAVSSGYEQGKVPEVPR 3199
            L+      +A    K  + Y   ASP +   +S AP         +++      +P VP 
Sbjct: 650  LESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTT------LPLVPT 703

Query: 3200 AGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGP 3259
            A +   V+ SP  T    +    L   +P++      +   +     T P +++++ +  
Sbjct: 704  ASENCPVAPSPQNTCAPLATLV-LAPEIPKS------VPSPSLPPAGTPPGTKKVDGISH 756

Query: 3260 GSSGRP-GKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTH 3318
             S+  P    P E    D        ++G      DS  P G    +       RP +  
Sbjct: 757  TSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLG----VSVSPQTKRPPTKK 812

Query: 3319 YYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEA 3378
                              G  GP  P  +L+      + S   +  +  + SK SP    
Sbjct: 813  ------------------GSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854

Query: 3379 KDVESDLASYPPPAVSSSLVSRGRKF--QDEITYGLKKNVYEQQKYYGMSSRDAVEDDRI 3436
                      P P+  + L  +G     ++  T  +    + ++     + + A      
Sbjct: 855  SPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMT 914

Query: 3437 YGGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPP 3496
                 ++RA  A  G   S        KG      A     K GP   S   A +   PP
Sbjct: 915  SSSPKKARATPAPKGIPASPSP-----KGAPTPPAATPPSPKGGPATPSPKWAPT---PP 966

Query: 3497 MRSQASEEESPV--SPLGRPRP--AGGPLPPGGDTCPQFCSSHSMPDVQE-HVKDGPRAH 3551
              +  S +  P   SP G P P  A  P P GG   P    + + P V     K  P A 
Sbjct: 967  AATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAAT 1026

Query: 3552 AYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRG 3611
             + +        +      S A             P+ A +         A +  S K G
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAAT---------PLPKGAPTTP-------AATLPSPKGG 1070

Query: 3612 PARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHA 3671
            PA  S      PP     P  +GGP   +             S +      G  A  PH 
Sbjct: 1071 PATPSLKGAPTPPA-ATPPSPKGGPATPSPKGAPMPPAATPPSPK------GGLATPPHK 1123

Query: 3672 RDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSG 3731
                   A P S        P KG P  P++   + PS        A+   KG   A + 
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAA---TPPSPKGGL---ATPPPKG---APTT 1174

Query: 3732 PAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPS---GAASRQPQTQQQQQGLGLQ 3788
            PAA          P  +G  A P P+ + +  +   PS   G A+  P+           
Sbjct: 1175 PAA--------TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1226

Query: 3789 PPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---PPRAEQTNGS 3845
             P+  L  A    +  PTT    PAA+ P+  P+ GP+T   P P G   PP A   +  
Sbjct: 1227 SPKGGL--ATPSPKGAPTT----PAATPPS--PKGGPAT---PPPKGAPTPPAATPPSLK 1275

Query: 3846 KGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
             G A  P +G AP       P P G  A + P G P  PA  P
Sbjct: 1276 GGLATPPHKG-APNPAVVTPPSPKGGPATSPPKGAPTPPAATP 1317



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 85/366 (23%), Positives = 130/366 (35%), Gaps = 65/366 (17%)

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            DP      PL+P  +P         +TP+  D +   V P   V+   A  T  P     
Sbjct: 1401 DPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTP---VSLKKAPATSAP---KG 1454

Query: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418
             PA+PSS            P  PA T  +P     P+   T +SP  +  +P+P      
Sbjct: 1455 GPATPSSKGD---------PTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM----- 1500

Query: 1419 YGHSPTTANYGSQTEDLPQAPSG-----LAAAGRAAREKPLSASDGEGGTPQ-------- 1465
             G     A   S  +++P  PS         A   +++ P + +  E   P         
Sbjct: 1501 -GAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPK 1559

Query: 1466 -----------PSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514
                       P+   S  ASS P ++PS+   +P+     + P  T+    + P+P   
Sbjct: 1560 KTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAV 1619

Query: 1515 SDMPRSPGAPTPSPMVAQGTQT---------PHRPSTPRLVWQESSQEAPFMVITLAS-- 1563
            +      G  TP+P   +GT T            P++P  V  +     P     L +  
Sbjct: 1620 TPPSPEKGPATPAP---KGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKK 1676

Query: 1564 --DASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSA 1621
               A  +  +  A  ST  + +PT   P T   S T+PP    + P+P    G     S 
Sbjct: 1677 GPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPP----ICPDPSAKNGSKGPLST 1732

Query: 1622 GADGPL 1627
             A  PL
Sbjct: 1733 VAPAPL 1738



 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 64/239 (26%), Positives = 83/239 (34%), Gaps = 38/239 (15%)

Query: 2129 PQHGPGLSAPQS------LVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLP 2182
            P+  P LS   S        P   G+  +P+ P+G P+P       P  G  T   +  P
Sbjct: 905  PKQAPALSMTSSSPKKARATPAPKGIPASPS-PKGAPTPPAATPPSPKGGPATPSPKWAP 963

Query: 2183 STATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLT 2242
            +                +P  A  P    P     P  +GG   P   G  T        
Sbjct: 964  TPPAATPPSPKGGPATPSPKGAPTPPAATP-----PSPKGGPATPSPKGAPTP------- 1011

Query: 2243 RVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVY-LGKPAAAKAPGAGGPSRPEM 2301
              P + P  P G       PA + FP  +S PPA  P    G PAA   P  G P+ P  
Sbjct: 1012 --PAVTPPSPKGS------PAATPFPKGASTPPAATPPSPKGSPAATPLP-KGAPTTPAA 1062

Query: 2302 PVGAAREEP-------LPTTTPAAIKEAAGAPA-PAPLAGQKPPADAAPGGGSGALSRP 2352
             + + +  P        PT   A      G PA P+P     PPA A P    G L+ P
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA-ATPPSPKGGLATP 1120



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 108/461 (23%), Positives = 147/461 (31%), Gaps = 87/461 (18%)

Query: 3478 KAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSM 3537
            K GP  S    A +   PP  +  S + SP    G P P G P PP   T P    + ++
Sbjct: 1298 KGGPATSPPKGAPT---PPAATPPSPKGSP----GTPPPKGAPTPPAV-TPPSPKGTPTL 1349

Query: 3538 PDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRH 3597
            P      K GP   + K  EG                            P  A      H
Sbjct: 1350 PATTPSSKGGPTTPSSK--EG--------------------------PTPPAATPS---H 1378

Query: 3598 HGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRH 3657
             GG A++  S KRGPA  S     +P    + P     P +  +    R G      G  
Sbjct: 1379 KGGPAMTPPSPKRGPAIPS--PKGDPTSPAVIPLS---PKKAPATPVTREGAATPSKGDL 1433

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPK-KGQPGYPSSAEYS--QPSRASSA 3714
            T          P    +   +A   S P   PA P  KG P  P+    S  +P      
Sbjct: 1434 T---------PPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQV 1484

Query: 3715 YHHASDSKKGSRQAHSGPAAL-----QSKAEPQAQPQLQGRQAAP-------------GP 3756
               +S  K  +  A  G   L      S  E  A P  +    AP              P
Sbjct: 1485 ATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAP 1544

Query: 3757 QQSQSPSSRQIPSGAASRQPQTQQQQQGL-----GLQPPQQALTQARLQQQSQPTTRGSA 3811
            +++  P +  +PS   +    T ++            PP  A+T +  +    P      
Sbjct: 1545 KEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPP--AVTPSTYKGAPSPKELLIP 1602

Query: 3812 PAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV 3871
            PA + P+ K  P P   T P P   P    T   KGT  +P    +        P     
Sbjct: 1603 PAVTSPSPKEAPTPPAVTPPSPEKGP---ATPAPKGTPTSPPVTPSSLKDSPTSPASVTC 1659

Query: 3872 KAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLT 3912
            K GA     P A  G P   G +   ++L   A E    +T
Sbjct: 1660 KMGAT---VPQASKGLPAKKGPTALKEVLVAPAPESTPIIT 1697



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 58/230 (25%), Positives = 88/230 (38%), Gaps = 10/230 (4%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
            P  + S+ P  P        S  E S     S ++  + DS   +      P + +    
Sbjct: 809  PTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPT--PPSPKGAPT 866

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIP---SGAASRQPQTQQQQQGLGLQPPQQALTQA 3797
            P A   L  +     P+++ +PS   +P    G A+  P+           P +   T A
Sbjct: 867  PSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPALSMTSSSPKKARATPA 926

Query: 3798 RLQQQSQPTTRGSA--PAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQG 3855
                 + P+ +G+   PAA+ P+  P+ GP+T + P+ A  P A      KG    P   
Sbjct: 927  PKGIPASPSPKGAPTPPAATPPS--PKGGPATPS-PKWAPTPPAATPPSPKGGPATPSPK 983

Query: 3856 RAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAA 3905
             AP    A  P P G  A   P G P  PA  P +   S  +   P GA+
Sbjct: 984  GAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGAS 1033



 Score = 53.1 bits (126), Expect = 5e-06
 Identities = 60/230 (26%), Positives = 78/230 (33%), Gaps = 18/230 (7%)

Query: 2137 APQSLVPLRPGLLGNPTFP--EGHPSPGNLAQYGPAAGQGTAVRQ--LLPSTATVRAADG 2192
            AP +     P   G P  P  +G P+P       P  G  T   +   +P  AT  +  G
Sbjct: 1056 APTTPAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKG 1115

Query: 2193 MIYSTINTPIAATLPITTQPA---SVLRPMVRGGMYRPYAS-----GGITAVPLTSLTRV 2244
             + +T     A T P  T P+    +  P  +G    P A+     GG+   P       
Sbjct: 1116 GL-ATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTT 1174

Query: 2245 PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVG 2304
            P   P  P G       P+P   P   +  P      L  P+   AP     + P    G
Sbjct: 1175 PAATPPSPKGGLAT---PSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1231

Query: 2305 AAREEP--LPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRP 2352
             A   P   PTT  A      G PA  P  G   P  A P    G L+ P
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATP 1281



 Score = 50.4 bits (119), Expect = 3e-05
 Identities = 155/697 (22%), Positives = 221/697 (31%), Gaps = 91/697 (13%)

Query: 1310 PGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKE 1369
            P  +P+    P + S+ T S S        + V   F+      L L SSP +       
Sbjct: 375  PVVAPSVDKGPSTISSITCSPSGS------LNVATSFSLSPTTSLILKSSPNATYHYPLV 428

Query: 1370 IGMPFSQGPGTPATTAVAPCP-AGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANY 1428
              MP S   GT       PC  A  P      A+      S  P S        PT+   
Sbjct: 429  AQMPVSS-VGTTPLVVTNPCTIAAAPTTTFEVATCVSPPMSSGPISNIE-----PTSPAA 482

Query: 1429 GSQTEDLPQAPSG-LAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSE 1487
                   P+ PS  +A   R     PL   D E     PS     F +     +  +  E
Sbjct: 483  LVMAPVAPKEPSTQVATTLRIPVSPPLP--DPEDLKNLPSSVLVKFPTQKDLQTVPASLE 540

Query: 1488 SPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVW 1547
               FSP + G        T    P     +P    AP  SP     + +P  P +P    
Sbjct: 541  GAPFSPAQAG-------LTTKKDPTV---LPLVQAAPKNSPSFQSTSSSPEIPLSPEATL 590

Query: 1548 QESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHG---YSQTTPPSVSQ 1604
             + S   P   + +   ASS T  +  ++S S + + +   P + G    S    P+V+ 
Sbjct: 591  AKKSLGEP---LPIGKPASSMTSPLGVNSSASVIKTDSYAGPDSAGPLLKSSLITPTVAA 647

Query: 1605 LPPEPPGPPGFPRVPSAGADGPLA-----LYGWGAL-----PAENISLCRISSVPGTSRV 1654
             P E   P G     + G           L G  +L     P +  +L  +  VP  S  
Sbjct: 648  FPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPTASEN 707

Query: 1655 EPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPL 1714
             P   +P      L T V    I    + +   SL       G     + G   T+    
Sbjct: 708  CPVAPSPQNTCAPLATLVLAPEI---PKSVPSPSLPPAGTPPGTK--KVDGISHTSALAP 762

Query: 1715 VINLNAQEHTFLATATTVSITMASSVFMAQQKQPV-VYGDPYQSRLDFGQGGGSPVCLAQ 1773
            V +   +  T  + A+  + +  +  ++A    P+ V   P   R    +G   P     
Sbjct: 763  VASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPD--TP 820

Query: 1774 VKQVEQAVQTAPYRSGPRGRPREAKFARYNLP-NQVAPLARRDVLITQMGTAQSIGLKPG 1832
            +  +   V            P EA F    LP N ++    +D   T             
Sbjct: 821  IGNLSSPVS-----------PVEASF----LPENSLSFQGSKDSPATTHSPTP------- 858

Query: 1833 PVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGM 1892
            P P+    P   TP   +   LP    P   VV +     G  T    + PA  L +T  
Sbjct: 859  PSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQAPA--LSMTSS 916

Query: 1893 RPESQLACCDMVYKLPFGSSCTGTFHP----------APSVPEKSMADAAPPGQSSSPFY 1942
             P+   A       +P   S  G   P           P+ P    A   P     SP  
Sbjct: 917  SPKKARAT-PAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975

Query: 1943 GPRDPEPPEPPTYRAQGVVGP--GPHEEQRPYPQGLP 1977
            GP  P P   PT  A     P  GP     P P+G P
Sbjct: 976  GPATPSPKGAPTPPAATPPSPKGGP---ATPSPKGAP 1009



 Score = 49.7 bits (117), Expect = 6e-05
 Identities = 73/311 (23%), Positives = 111/311 (35%), Gaps = 38/311 (12%)

Query: 3630 PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAP 3689
            P  +G P   A+      G  G  +  H G  P      P +   G   + P   P+   
Sbjct: 1258 PPPKGAPTPPAATPPSLKG--GLATPPHKGA-PNPAVVTPPSPKGGPATSPPKGAPTPPA 1314

Query: 3690 AMPK--KGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSG----PAALQSKAEPQA 3743
            A P   KG PG P       P   +      + +   +  +  G    P++ +    P A
Sbjct: 1315 ATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAA 1374

Query: 3744 QPQLQGRQAA--PGPQQSQS-PSSRQIPSGAA------SRQPQTQQQQQGLG------LQ 3788
             P  +G  A   P P++  + PS +  P+  A       + P T   ++G        L 
Sbjct: 1375 TPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLT 1434

Query: 3789 PPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGT 3848
            PP  A+T   L++   P T       + P+ K  P     T P P  PP  +Q   S   
Sbjct: 1435 PP--AVTPVSLKKA--PATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP 1490

Query: 3849 AKAPQQGRAPQAQPAPGPGPA-GVKAGARPGGTPGAPAGQ--PGADGESVFSKILPGGAA 3905
             KAP       A PAP   P       + P   P  P+ +  P A   ++ SK  P   A
Sbjct: 1491 KKAP-------ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLA 1543

Query: 3906 EQAGKLTEAVS 3916
             +   +  A++
Sbjct: 1544 PKEALIPPAMT 1554



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 61/227 (26%), Positives = 84/227 (37%), Gaps = 31/227 (13%)

Query: 2122 PDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLL 2181
            P +     +  P  SAP+   P  P   G+PT P   P         P+  +  A +Q+ 
Sbjct: 1436 PAVTPVSLKKAPATSAPKG-GPATPSSKGDPTLPAVTP---------PSPKEPPAPKQVA 1485

Query: 2182 PSTATVRAADGMIYSTINTPIAATLP--ITTQPASV-LRPMVRGGMYRPYASGGITAVPL 2238
             S++  +A      +T     A TLP  I + P  V   P  R     P A+      P 
Sbjct: 1486 TSSSPKKAP-----ATPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPA 1540

Query: 2239 TSLTRVPMIAPRVPL-GPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS 2297
            T   +  +I P + +  P      P P   P   S   A  P     PA   +   G PS
Sbjct: 1541 TLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSP-----PAVTPSTYKGAPS 1595

Query: 2298 RPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGG 2344
              E+ +  A   P P       KEA   PA  P + +K PA  AP G
Sbjct: 1596 PKELLIPPAVTSPSP-------KEAPTPPAVTPPSPEKGPATPAPKG 1635



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 60/231 (25%), Positives = 81/231 (35%), Gaps = 30/231 (12%)

Query: 2129 PQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPST--AT 2186
            P H    + P +  P   G L  P  P+G P+        P  G  T   +  P+T  AT
Sbjct: 1120 PPHKGAPTTPAATPPSPKGGLATPP-PKGAPTTPAATPPSPKGGLATPPPKGAPTTPAAT 1178

Query: 2187 VRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPM 2246
              +  G + +T +   A T P  T P+       +GG+  P   G  T    T       
Sbjct: 1179 PPSPKGGL-ATPSPKGAPTTPAATPPSP------KGGLATPSPKGAPTTPAAT------- 1224

Query: 2247 IAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP---SRPEMPV 2303
                 P  P G    P+P   P   + P A  P   G PA     GA  P   + P +  
Sbjct: 1225 -----PPSPKGGLATPSPKGAP---TTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKG 1276

Query: 2304 GAAREEPLPTTTPAAIKEAA--GAPAPAPLAGQKPPADAAPGGGSGALSRP 2352
            G A         PA +   +  G PA +P  G   P  A P    G+   P
Sbjct: 1277 GLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTP 1327



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 134/661 (20%), Positives = 226/661 (34%), Gaps = 130/661 (19%)

Query: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGL--------PRGYMTPASPAGSERSPSPSS 1414
            P  A++ +     + P   A TAV P  + L        P   + P      ++ P  ++
Sbjct: 2    PGEATETVPATEQELPQPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAA 61

Query: 1415 TAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFA 1474
               S   SP+T          PQ+ SG A     A E P    +  G    P+      A
Sbjct: 62   NQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPISPAA----LA 117

Query: 1475 SSSPPLSPS---SPSESPTFSPGKMGPRATAEFS-------TQTPSPAPAS-------DM 1517
             +SP ++P+   +PS S   +   + P +  + S       T  PS A A          
Sbjct: 118  LASPMIAPTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAESGSVITLSA 177

Query: 1518 PRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS 1577
            P +P  P  +         P+   TP           P +V T+     +    + +  +
Sbjct: 178  PIAPSEPKTNLNKVPSEVVPNPKGTP---------SPPCIVSTVPYHCVTPMASIQSGVA 228

Query: 1578 TSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPA 1637
            + P  +PT T        + T  S   + P+ PG        S    GP++       P 
Sbjct: 229  SLPQTTPTTTLAIASPQVKDTTISSVLISPQNPG--------SLSLKGPVS-------PP 273

Query: 1638 ENISLCRIS-SVPGTSRVEPGPRTPGTAVVDLRTAVKPT---------------PIILTD 1681
              +SL   S  V  +S+   GP TP    + L + + P                P  L+D
Sbjct: 274  AALSLSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPSALSD 333

Query: 1682 Q-----GMDLTSLAVEARKYGLALDPIPGRQ-----STAVQPLVI-----------NLNA 1720
                   +D +S           + P+P R      + A  P+V            ++  
Sbjct: 334  PTVKTISVDHSSTGASYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISSITC 393

Query: 1721 QEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQA 1780
                 L  AT+ S++  +S+ + +      Y  P  +++     G +P+ +     +  A
Sbjct: 394  SPSGSLNVATSFSLSPTTSLIL-KSSPNATYHYPLVAQMPVSSVGTTPLVVTNPCTIAAA 452

Query: 1781 VQTA---------PYRSGPRGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKP 1831
              T          P  SGP         A       +AP+A ++   TQ+ T   I + P
Sbjct: 453  PTTTFEVATCVSPPMSSGPISNIEPTSPAAL----VMAPVAPKEP-STQVATTLRIPVSP 507

Query: 1832 GPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTG 1891
             P+P+P  E  +  P+ +     P  +   TV   + EG         P  PA A    G
Sbjct: 508  -PLPDP--EDLKNLPSSVLV-KFPTQKDLQTVPASL-EGA--------PFSPAQA----G 550

Query: 1892 MRPESQLACCDMVYKLPFGSSCTGTFHPAPSVP--------EKSMADAAPPGQSSSPFYG 1943
            +  +       +V   P  S    +   +P +P        +KS+ +  P G+ +S    
Sbjct: 551  LTTKKDPTVLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKPASSMTS 610

Query: 1944 P 1944
            P
Sbjct: 611  P 611



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 58/237 (24%), Positives = 78/237 (32%), Gaps = 33/237 (13%)

Query: 2137 APQSLVPLRPGLLGNPTFP--EGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMI 2194
            AP +     P   G P  P  +G P+P          G  T   +  P+ A V       
Sbjct: 1240 APTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKG 1299

Query: 2195 YSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLT-----SLTRVPMIAP 2249
                + P  A  P    P     P  +G    P   G  T   +T         +P   P
Sbjct: 1300 GPATSPPKGAPTPPAATP-----PSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTP 1354

Query: 2250 RVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPE--------- 2300
                GPT     P+    P     PPA  P + G PA        GP+ P          
Sbjct: 1355 SSKGGPTT----PSSKEGP----TPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPA 1406

Query: 2301 -MPVGAAREEPLPTTTPAAIKEAAG---APAPAPLAGQKPPADAAPGGGSGALSRPG 2353
             +P+   +    P T   A   + G    PA  P++ +K PA +AP GG    S  G
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG 1463



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 60/247 (24%), Positives = 80/247 (32%), Gaps = 49/247 (19%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFP 3095
            PAT ++   P+ P        +PPAP+  A S  P        +AP  P P    AP  P
Sbjct: 1456 PATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSP-------KKAPATPAP--MGAPTLP 1506

Query: 3096 PGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQ 3155
              A  P+ P                   +P T S+     A +   L K    +LA  E 
Sbjct: 1507 --AVIPSSP-----------------KEVPATPSSRRDPIAPTATLLSKKTPATLAPKEA 1547

Query: 3156 KVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYP 3215
             +P    V +    P    P E     PA  S  E    P V  +  +G+ S       P
Sbjct: 1548 LIPPAMTVPSPKKTPAIPTPKE----APATPSSKEASSPPAVTPSTYKGAPSPKELLIPP 1603

Query: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVL 3275
            + +  +  E   P                 +  P S    P  P   G P   P  P  L
Sbjct: 1604 AVTSPSPKEAPTP----------------PAVTPPSPEKGPATPAPKGTPTSPPVTPSSL 1647

Query: 3276 -DGPTLP 3281
             D PT P
Sbjct: 1648 KDSPTSP 1654



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 95/375 (25%), Positives = 125/375 (33%), Gaps = 59/375 (15%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            TTPA      P+    PATPS   A   P   PP+P+   G   P+  G P   A T P 
Sbjct: 1058 TTPAATL---PSPKGGPATPSLKGAPTPPAATPPSPK--GGPATPSPKGAPMPPAATPPS 1112

Query: 3086 PS------------TYPAPAFPP----GASYPAEPGLPNQQAFRPTGHYAG-QTP----M 3124
            P             T PA A PP    G + P   G P   A  P     G  TP     
Sbjct: 1113 PKGGLATPPHKGAPTTPA-ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGA 1171

Query: 3125 PTTQSTLFPVPADSRA-PLQKPRQTSLADLEQKVPTNYEVIA---SPVVPMSSAPSETSY 3180
            PTT +   P P    A P  K   T+ A             +   +P  P ++ PS    
Sbjct: 1172 PTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK-- 1229

Query: 3181 SGPAVSSGYEQGKVPEVPRAGDRGSVSQSP---APTYPSDSH-------YTSLEQNVPRN 3230
             G A  S       P       +G  +  P   APT P+ +         T   +  P  
Sbjct: 1230 GGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNP 1289

Query: 3231 YVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEE 3290
             V+        K   +T+P      P    +   P   PG P     PT P       + 
Sbjct: 1290 AVV---TPPSPKGGPATSPPKGAPTP-PAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKG 1345

Query: 3291 SEE-DSYDPRGKGGHL--RSMESNGRPASTHYYGDSDYRHGARV----EKYGPGPMGPKH 3343
            +    +  P  KGG     S E    PA+T       ++ G  +     K GP    PK 
Sbjct: 1346 TPTLPATTPSSKGGPTTPSSKEGPTPPAAT-----PSHKGGPAMTPPSPKRGPAIPSPKG 1400

Query: 3344 PSKSLAPAAISSKRS 3358
               S A   +S K++
Sbjct: 1401 DPTSPAVIPLSPKKA 1415



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 47/204 (23%), Positives = 63/204 (30%), Gaps = 37/204 (18%)

Query: 2152 PTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQ 2211
            P  P+G P+P             +AV  L P   T+   +    S +N P     P T  
Sbjct: 858  PPSPKGAPTP-------------SAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPA 904

Query: 2212 PASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPI-- 2269
            P                        P  S+T       R    P G+   P+P   P   
Sbjct: 905  PKQA---------------------PALSMTSSSPKKARATPAPKGIPASPSPKGAPTPP 943

Query: 2270 ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPA-P 2328
            A++ P  +G      P  A  P A  P  P+        +  PT   A      G PA P
Sbjct: 944  AATPPSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATP 1003

Query: 2329 APLAGQKPPADAAPGGGSGALSRP 2352
            +P     PPA   P       + P
Sbjct: 1004 SPKGAPTPPAVTPPSPKGSPAATP 1027



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 63/225 (28%), Positives = 82/225 (36%), Gaps = 39/225 (17%)

Query: 3023 QGCTTPAGQFVDFPATAAAPA-TPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAP 3081
            +G  TP    V  P+   +PA TP    A   P   PP+P+ S  +  P   G P   A 
Sbjct: 1006 KGAPTPPA--VTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAAT-PLPKGAPTTPAA 1062

Query: 3082 TYPGPSTYPA----------PAFPP-----GASYPAEPGLPNQQAFRPTGHYAG-QTP-- 3123
            T P P   PA          PA  P     G + P+  G P   A  P     G  TP  
Sbjct: 1063 TLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPH 1122

Query: 3124 --MPTTQSTLFPVPADSRA-PLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSY 3180
               PTT +   P P    A P  K   T+ A      P+    +A+P  P   AP+  + 
Sbjct: 1123 KGAPTTPAATPPSPKGGLATPPPKGAPTTPA---ATPPSPKGGLATP--PPKGAPTTPAA 1177

Query: 3181 SGPAVSSGYEQGK---VPEVPRA------GDRGSVSQSPAPTYPS 3216
            + P+   G         P  P A      G   + S   APT P+
Sbjct: 1178 TPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPA 1222



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 71/329 (21%), Positives = 96/329 (29%), Gaps = 57/329 (17%)

Query: 3039 AAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYP-APAFPPG 3097
            A  P++  GPT         P     +  GGP        + P  P P   P +PA  P 
Sbjct: 1351 ATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIP- 1409

Query: 3098 ASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADS------RAPLQK------- 3144
             S    P  P  +    T      TP   T  +L   PA S        P  K       
Sbjct: 1410 LSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPTLPA 1469

Query: 3145 -----------PRQTSLADLEQKVPTNYEVIASPVVP--MSSAPSETSYSGPAVSSGYEQ 3191
                       P+Q + +   +K P     + +P +P  + S+P E     PA  S    
Sbjct: 1470 VTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEV----PATPSSRRD 1525

Query: 3192 GKVPE------------------VPRAGDRGSVSQSP-------APTYPSDSHYTSLEQN 3226
               P                   +P A    S  ++P       AP  PS    +S    
Sbjct: 1526 PIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAV 1585

Query: 3227 VPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYAR 3286
             P  Y       EL      T+P  +        +   P K P  P     PT P     
Sbjct: 1586 TPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPS 1645

Query: 3287 GEEESEEDSYDPRGKGGHLRSMESNGRPA 3315
              ++S         K G      S G PA
Sbjct: 1646 SLKDSPTSPASVTCKMGATVPQASKGLPA 1674



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 60/247 (24%), Positives = 85/247 (34%), Gaps = 40/247 (16%)

Query: 2124 LVQYQPQHGPGLSAPQSL--VPLRPGL------LGNPTFPEGHPSPGNLAQYGPAAGQGT 2175
            LVQ  P++ P   +  S   +PL P        LG P  P G P+    +   P     +
Sbjct: 562  LVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEP-LPIGKPAS---SMTSPLGVNSS 617

Query: 2176 AVRQLLPSTATVRAADGMIYSTINTPIAATLPI-TTQPASVLRPMVRGGMY-----RPYA 2229
            A      S A   +A  ++ S++ TP  A  P+ +  PA V     +G         P+ 
Sbjct: 618  ASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFL 677

Query: 2230 SGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAK 2289
             G ++  P     +   +   +PL PT      A    P+A S            P    
Sbjct: 678  EGTVSLAPKNHPVKEGTLTT-LPLVPT------ASENCPVAPS------------PQNTC 718

Query: 2290 APGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAG---APAPAPLAGQKPPADAAPGGGS 2346
            AP A     PE+P         P  TP   K+  G     A AP+A           G S
Sbjct: 719  APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGAS 778

Query: 2347 GALSRPG 2353
               S  G
Sbjct: 779  ATASSKG 785



 Score = 35.8 bits (81), Expect = 0.86
 Identities = 79/337 (23%), Positives = 117/337 (34%), Gaps = 57/337 (16%)

Query: 1090 SKTPPSNLSPIEDA-SPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYK 1148
            SK  P+ L+P E    P   +    +   +     +  +PS    S   A+     +   
Sbjct: 1535 SKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAP 1594

Query: 1149 SGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGA 1208
            S  E  +P  ++  SP E P+  + TP S                       ++G A  A
Sbjct: 1595 SPKELLIPPAVTSPSPKEAPTPPAVTPPS----------------------PEKGPATPA 1632

Query: 1209 RGPHGGP-SQPTGPRGL-GSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQS 1266
              P G P S P  P  L  S     +   + G     A++G PA  G    +E+L     
Sbjct: 1633 --PKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAP-- 1688

Query: 1267 IVRMRQASSRDLAFAEDKK---KEKQFLNAESAYMDPMKQNG--GPLTPGTSPTQLAAPV 1321
                    S  +  A  +K    +K    +     DP  +NG  GPL+     T   AP+
Sbjct: 1689 -----APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLS-----TVAPAPL 1738

Query: 1322 SFSTPTSSDSSGGRVIPDVRVTQHFAK-ETQDPLKLHSSPASPSSASKEIGMP----FSQ 1376
                P   DSS      D     H  K     P    S+P + ++  K +  P     S 
Sbjct: 1739 ---LPVQKDSSKTAKGKD---ASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA 1792

Query: 1377 GPGTPATTAVAPCPAGL--PRGYMTPASPAGSERSPS 1411
             P  P +  +AP P     P+    P+SP     SPS
Sbjct: 1793 APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPS 1829



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 39/176 (22%), Positives = 65/176 (36%), Gaps = 24/176 (13%)

Query: 2196 STINTPIAATLPIT---TQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
            +T + P+ A +P++   T P  V  P              I A P T+      ++P + 
Sbjct: 421  ATYHYPLVAQMPVSSVGTTPLVVTNPCT------------IAAAPTTTFEVATCVSPPMS 468

Query: 2253 LGPTGLYRYPAPSRF---PIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREE 2309
             GP       +P+     P+A   P  +    L  P +   P         +P     + 
Sbjct: 469  SGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRIPVSPPLPDP--EDLKNLPSSVLVKF 526

Query: 2310 PLPT---TTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQE 2362
            P      T PA+++ A  +PA A L  +K P    P   +   + P F+   +S E
Sbjct: 527  PTQKDLQTVPASLEGAPFSPAQAGLTTKKDPT-VLPLVQAAPKNSPSFQSTSSSPE 581


>gi|188536004 zinc finger protein 469 [Homo sapiens]
          Length = 3925

 Score = 99.4 bits (246), Expect = 6e-20
 Identities = 355/1598 (22%), Positives = 500/1598 (31%), Gaps = 249/1598 (15%)

Query: 2    GNEVSLEGGAGDGPLPPGGAGPGPGPG--PGPGAGKPPSAPAGG----------GQLPAA 49
            G   S   G    P  P G  P   P    G   G PP     G           + P  
Sbjct: 80   GQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKPTLDETPEN 139

Query: 50   GAARSTAVPPVPGP-GPGPGPGPGPGSTSRRLDPK-EPLGNQRAASPTPKQASATTPGHE 107
                +  +P V  P GPG G    PG       P  E LG  R     P  +S T+  + 
Sbjct: 140  PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPP--SSFTSTNYT 197

Query: 108  SPRETR---AQGPAGQEADGPRRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIA 162
            SP  T    A GP       P   LQ  S    Q SG          S P + + VP   
Sbjct: 198  SPSATPRPPAPGPPQSRGTSP---LQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAE 254

Query: 163  PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222
            P P      I K S    +P   +F       +      G +  P    V      N  +
Sbjct: 255  PEP------IPKGSRPGGSPRGVSFQFPFPALH------GASTKPFPADVAGHAFTNGPL 302

Query: 223  QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282
              A        P         +    PA+    QP   P       PGG    +R ++ +
Sbjct: 303  VFAFHQPQGAWPEE-------AVGTGPAYPLPTQPAPSPLPCYQGQPGGL---NRHSDLS 352

Query: 283  RATSVPGPAQAAAPP-------EVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAG 335
             A S PG A +A  P        + ++ P+ P   +      R P    P +        
Sbjct: 353  GALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYR 412

Query: 336  LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP--APSKGTPKIVFNDASK 393
                + +      +L   G      A       P A     P   P   T  + FN    
Sbjct: 413  ASGVDTSPGPPDTELAAPGPP---PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG--- 466

Query: 394  EAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAA 453
            +  P      P   P P  +  P AR  P  G   L +          +   Q A   A 
Sbjct: 467  QPSPGQRLCLPQSAPLPWPQVLPTARPSP-HGMEMLSRLPFPAGGPEWQGGSQGALGTAG 525

Query: 454  KPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP--TPHLVEKTEWL 511
            K    P  R   P  ++    GS +   YN  T    Q        P  +PH        
Sbjct: 526  KT---PGPREKLPAVRSSQG-GSPALFTYNGMTDPGAQPLFFGVAQPQVSPH-------- 573

Query: 512  CLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAK 571
                          G P+ LPPP           R  G SP +   P      +G   + 
Sbjct: 574  --------------GTPS-LPPP-----------RVVGASPSESPLPSPATNTAGSTCSS 607

Query: 572  ASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKP------PPE 625
             SP+S+  +   S+ S    PL  S     P+  QE  +  P+   P   P      P +
Sbjct: 608  LSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSPEPPHSLPTHYQPEPAK 667

Query: 626  TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGG-EAEDLVGKPY-SQDASRSPQSLS-- 681
              P PA      G  +    TP     PE  +GG +       PY +   S S  SL   
Sbjct: 668  AFPFPADGLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQL 727

Query: 682  ---------DTGYSSDGISSSQSEITGVVQQEVE--QLDSAGVTG-PHPPS----PSEIH 725
                     D  YSS     +  +  G++    +     S G  G P PP+    P++ H
Sbjct: 728  DVLLTCRQCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAH 787

Query: 726  K-VGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEED 784
              + S  +  L A       +  PL +G        P  L  +    + D +L+ ++ E 
Sbjct: 788  AGLLSHAKTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASDLDMEDDAKLDSLITEA 847

Query: 785  EDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMR 844
             +  E+     Q D  E    F       + ++   G   P    P    A +T E    
Sbjct: 848  LNGMEY-----QSDNPEIDSSFIDV----FADEEPSGPRGPSSGHPLKSKAGVTPESKAP 898

Query: 845  RQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTG 904
              +   + +       D     RG  K  +    P     PSQ       ++L       
Sbjct: 899  PPLPAATPDPQTPRPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKL----- 953

Query: 905  YEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELD-LGQGPDPSLDREPELE 963
            + + L  GG+AE   GSG+  GG          ++G      D LG+ P P   R P  +
Sbjct: 954  FRKDLDSGGAAE---GSGSGGGG---------RASGLRPRRNDGLGERPPPR-PRRPRTQ 1000

Query: 964  MESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQR 1023
                   P  R     ++ LP  T S                     SRR+RL   K  R
Sbjct: 1001 APGSRADPAPRV--PRAAALPEETRS---------------------SRRRRLPPRKDPR 1037

Query: 1024 KARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR- 1082
            K + R        I    +++    E +   E E   E EQ   R    + RR + E R 
Sbjct: 1038 KRKARGGAWGKELILKIVQQKNRLREYDFASESE---EDEQPPPRGPGFRGRRGRGEKRK 1094

Query: 1083 ----AQRRRERSKTPPSNLSPIE---DASPTEELRQAAEMEELHRSSCSEYSPSPSLDSE 1135
                 Q  RE     P   +  E   D +P              RS  +   PS SL++ 
Sbjct: 1095 EVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQAR-GPSRSLETG 1153

Query: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPL-----KSAEEAYEE 1190
            A A +GGP    K     ++     L  PT T +   T PS   P      ++AEE+  +
Sbjct: 1154 AAAREGGP----KCADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPD 1209

Query: 1191 MMRKAELLQRQQGQAAGARGPHGG---PSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG 1247
                 E L+      AG  G   G   P QP   R      +   T +  G  A  A  G
Sbjct: 1210 STEFTEALRSPPAACAGEMGASPGLLIPEQPPPSR------HDTGTPKPSGSLANTAPHG 1263

Query: 1248 TPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGP 1307
            +  + G      +L            +S+D                      P +Q G  
Sbjct: 1264 SSPTPGVG---SLLGGPGGTQAPVSHNSKD---------------------PPARQPGEF 1299

Query: 1308 LTPGTSPTQLAAPVS--FSTPTSS---DSSGGRVIP-DVRVTQHFAKETQDP-LKLHSSP 1360
            L P  +P+  A P     S+  SS   D +G    P  V V +   +    P  +L   P
Sbjct: 1300 LAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGP 1359

Query: 1361 ASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYG 1420
               +    E   P       P  ++   C  G   G + P  P      P  + T     
Sbjct: 1360 KDLAGCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLP---RSPPGTAETEPGRA 1416

Query: 1421 HSPTTANYGSQTEDLP--QAPSGLAAAGRAAREK--PLSASDGEGGTPQPSRAYSYFASS 1476
             SP T    S   DLP  +    L  +  A R+   P + +D    T      Y  F   
Sbjct: 1417 ASPPTLESSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLL 1476

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514
               +SP  PS  P  S GK+  +      T  P  AP+
Sbjct: 1477 E-EVSPMLPSHFPDLSGGKVLSKTCPPERTVVPGAAPS 1513



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 175/788 (22%), Positives = 258/788 (32%), Gaps = 155/788 (19%)

Query: 12   GDGPLP-----PGGAGPG---PGPGPG-------PGAGKP-----PSAPAGGGQLPAAGA 51
            GDG  P     P GA P     G   G       P AG+P       APAG   L A   
Sbjct: 1783 GDGAPPLDATWPFGASPSHAAQGHSAGRAGGHLHPTAGRPGFEGNEFAPAGASSLTAP-R 1841

Query: 52   ARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQAS-------ATTP 104
             R   + PVP P       P   S    L P  P+   +   P   ++          TP
Sbjct: 1842 GREAWLVPVPSPACVSNTHPSRRSQDPALSP--PIRQLQLPGPGVAKSKDGILGLQELTP 1899

Query: 105  GHESPRETR--------------AQGPA--------------------GQEADGPRRTLQ 130
              +SP                  A GPA                    G EADG    L 
Sbjct: 1900 AAQSPPRVNPSGLEGGTVEGGKVACGPAQGSPGGVQVTTLPAVAGHQLGLEADGHWGLLG 1959

Query: 131  VDSRTQRSGRSPSVSPDRGSTP------TSPYSVPQIA---PLPSSTLCPICKTS----- 176
               +TQ  G +  + P+ G +P       S  + P+ A   P   + L   CK S     
Sbjct: 1960 QAEKTQGQGTANQLQPENGVSPGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMS 2019

Query: 177  ---DLTSTPSQPNFN------TCTQCHNKVCNQCGFNP----NPHLTQVKEWLCLNCQMQ 223
               +   TPS P+ N        T  H++  ++ G  P    +P L   K  L       
Sbjct: 2020 LQEEAEPTPSPPSPNRESLALALTAAHSRSGSE-GRTPERASSPGLN--KPLLATGDSPA 2076

Query: 224  RALGMDMTTAPRSKSQQQLHS-----PALSPAHSPAKQPLG----KPDQERSRGPGGPQ- 273
             ++G     AP   S   +       P   P  SP++   G     P     R P GPQ 
Sbjct: 2077 PSVGDLAACAPSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPSCRDPPGPQQ 2136

Query: 274  --------PGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAP 325
                        +A+  +AT+  G   +   P     SP  P   K + A        +P
Sbjct: 2137 LLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP---KEALAGCLLQGEGSP 2193

Query: 326  AKSATAVPAG-LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTP 384
             +  ++ P G + A   T  G T K   L     ++   L      A +   P     +P
Sbjct: 2194 LEDPSSWPPGSVSAVTCTHSGDTPKDSTLRIPEDSRKEKLWESPGRATS--PPLAGAVSP 2251

Query: 385  KIVFNDASKEAGPKPLGSGPG---PGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKH- 440
             +        + P    +  G   PGP P ++  P     P + P  +P+   + SP + 
Sbjct: 2252 SVAVRATGLSSTPTGDEAQAGRGLPGPDPQSRGAP-----PHTNPDRMPRGHSSYSPSNT 2306

Query: 441  ---GRAEHQAASKAAAKPKTMPKERAICPLC-QAELNVGSKSPANYNTCTTCR------- 489
               G  E QA +    +P T+       P C + E+   SK P +  T  T R       
Sbjct: 2307 ARLGHREGQAVTAVPTEPPTLQGAGPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMP 2366

Query: 490  LQVCNLCGF---NPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR 546
               C   G      T      +++   + Q+ R       +  PL P   +Q   G   +
Sbjct: 2367 RVTCPSTGLGLGRTTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKK 2426

Query: 547  ASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK---ASPQAKPLRASEPSKTPS 603
             + T   + KG      P GP+  +    S ++ P  S+      +  P   +EPS    
Sbjct: 2427 PASTENGQWKGQ----APHGPVTCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAAL 2482

Query: 604  SVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAED 663
              Q+    +  K +     PP       + K +    R +P+   V   P A    E   
Sbjct: 2483 PAQQPLEPLAQKCQ-----PPRKKSHRVSGKERPNHSRGDPSH--VTQPPPAQGSKEVLR 2535

Query: 664  LVGKPYSQ 671
              G P+SQ
Sbjct: 2536 APGSPHSQ 2543



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 334/1501 (22%), Positives = 485/1501 (32%), Gaps = 239/1501 (15%)

Query: 224  RALGMDMTTA-PRSKSQQQLHSPAL-------------SPAHSPAKQPLGKPDQERSRGP 269
            +A  M++  A PR     +L  P+L             SP   P + PL  P +   R  
Sbjct: 54   QAQAMELPEAQPRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAE 113

Query: 270  GGPQP-------GSRQAETARATSVPGPAQAAAPPEV----GRVSPQPPQPTKPSTAEPR 318
            G P          SR   T   T      +AA  PEV    G  +  P +P  P T E +
Sbjct: 114  GSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRT-EAQ 172

Query: 319  PPAGEAPA-KSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLM-SVQPEADTQGQ 376
            P A E    +     P+   +T  T    T +    G       S L     PE    G 
Sbjct: 173  PAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQASGA 232

Query: 377  ----PAPSKGTPKIVFNDASKEAGPKPLGSGPGPGP-----------APGAKTEPGARMG 421
                PA     P   F     E  P P GS PG  P             GA T+P     
Sbjct: 233  DSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPFPADV 292

Query: 422  PGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPAN 481
             G      P       P+ G    +A     A P  +P + A  PL       G     N
Sbjct: 293  AGHAFTNGPLVFAFHQPQ-GAWPEEAVGTGPAYP--LPTQPAPSPL---PCYQGQPGGLN 346

Query: 482  YNTCTTCRLQVCNLCGFNPTP--HLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
             ++  +  L         P P    + K+    L  +     +G LG     P    Q+ 
Sbjct: 347  RHSDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDG-LGSTRGPPSSLPQRH 405

Query: 540  PVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPL-STKASPLPSKASPQAKPLRASEP 598
              G  +RASG           L  P GP PA+   L    A+P P   +P   PL A+  
Sbjct: 406  FPGQAYRASGVDTSPGPPDTELAAP-GPPPARLPQLWDPTAAPYP---TPPGGPLAATRS 461

Query: 599  ---SKTPSSVQEKKTRVPTKAE-PMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654
               +  PS  Q  +  +P  A  P P+  P   P+P   ++ S +       P     PE
Sbjct: 462  MFFNGQPSPGQ--RLCLPQSAPLPWPQVLPTARPSPHGMEMLSRL-------PFPAGGPE 512

Query: 655  APKG-----GEAEDLVGKPYSQDASRSPQSLSDTGYSSDGIS--SSQSEITGVVQQEVE- 706
               G     G A    G      A RS Q  S   ++ +G++   +Q    GV Q +V  
Sbjct: 513  WQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSP 572

Query: 707  ----QLDSAGVTGPHP-------PSPSEIHKVGSSMRPLLQAQGLAPSERSK-------- 747
                 L    V G  P       P+ +      SS+ P+  +     SE S+        
Sbjct: 573  HGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPS 632

Query: 748  --------PLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDT 799
                    P  +G+     + PHSL   P  +  +         D   AE   +  ++  
Sbjct: 633  AFFHPPTHPQETGSPFPSPEPPHSL---PTHYQPEPAKAFPFPADGLGAEGAFQCLEE-- 687

Query: 800  AESSDDFGSQLRHDYVEDSSEG--GLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNL 857
                    +   H+  E    G  G    PP  P     L+     +  +L    + D  
Sbjct: 688  --------TPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCRQCDRN 739

Query: 858  EEDDTATSGR----GL----AKHGTQKG-GPRPRPEPSQEPAALPKRRLPHNATTG---Y 905
                 A        GL    AK G Q+  GP   P P   P      R+P +A  G   +
Sbjct: 740  YSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAP------RVPADAHAGLLSH 793

Query: 906  EELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEME 965
             +     G A+A      L+ G        L +T       DL    D  LD    L  E
Sbjct: 794  AKTFLLAGDAQAEGKDDPLRTGF----LPSLAATPFPLPASDLDMEDDAKLD---SLITE 846

Query: 966  SLTGSPEDRSRGEHSSTL--------PASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLE 1017
            +L G        E  S+         P+     +SG    S + +  +S + P       
Sbjct: 847  ALNGMEYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATP 906

Query: 1018 EAKQQR----------KARHRSHGPLLPTIEDS-SEEEELREEEEL---LREQEKMREVE 1063
            + +  R          + + RS G L PT  D+ S+  + R  ++L    ++ +     E
Sbjct: 907  DPQTPRPGDRGCPARGRPKTRSLG-LAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAE 965

Query: 1064 QQRI----RSTARKTRRDK---EELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEME 1116
                    R++  + RR+    E    + RR R++ P S       A P   + +AA + 
Sbjct: 966  GSGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSR------ADPAPRVPRAAALP 1019

Query: 1117 ELHRSSCSEYSPSPSLDSEAEALDG--GPSRLYKSGSEYNLPTFMSLYSPTE-----TPS 1169
            E  RSS     P      + +A  G  G   + K   + N        S +E      P 
Sbjct: 1020 EETRSSRRRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPPPR 1079

Query: 1170 GSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQG--QAAGARGPHGGPSQPTGPRGLGSF 1227
            G       GR  K  E    +  R+ E  + ++   Q AG  G    P +P G R     
Sbjct: 1080 GPGFRGRRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGR 1139

Query: 1228 EYQDTTDREYGQAAQPAAEGTP--ASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKK 1285
              Q        +    A EG P  A   +   ++ LQ   +     + +   L F ++ K
Sbjct: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTN-TETSEETRPSLDFPQEAK 1198

Query: 1286 KEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQH 1345
            + +    AE +  D  +      +P   P   A  +         +S G +IP+      
Sbjct: 1199 EPE---TAEESAPDSTEFTEALRSP---PAACAGEMG--------ASPGLLIPEQPPPSR 1244

Query: 1346 FAKETQDPL-KLHSSPASPSSASKEIGMPFSQGPG---TPATTAVAPCPAGLPRGYMTPA 1401
                T  P   L ++    SS +  +G     GPG    P +      PA  P  ++ P 
Sbjct: 1245 HDTGTPKPSGSLANTAPHGSSPTPGVGSLLG-GPGGTQAPVSHNSKDPPARQPGEFLAPV 1303

Query: 1402 SPAGSERSPSP---SSTAHSYGHSPTTAN---------------YGSQTEDLPQAPSGLA 1443
            +   S   P P   SS   S+G  P   N               Y S   +L   P  LA
Sbjct: 1304 ANPSSTACPKPSVLSSKISSFGCDPAGFNRDPLGVPVAKKGPQPYSSPHSELFLGPKDLA 1363

Query: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
                       SA D    +          A S  P  P SP  +    PG+     T E
Sbjct: 1364 GCFLEELHPKPSARDAPPASSSCLCQDGEDAGSLEPQLPRSPPGTAETEPGRAASPPTLE 1423

Query: 1504 FSTQTPS-PAPASDMP--------RSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEA 1554
             S+  P  P    D P        R  G P       Q T     P    L+ +E S   
Sbjct: 1424 SSSLFPDLPVDRFDPPLYGSLSANRDSGLPFACADPPQKTVPSDPPYPSFLLLEEVSPML 1483

Query: 1555 P 1555
            P
Sbjct: 1484 P 1484



 Score = 50.4 bits (119), Expect = 3e-05
 Identities = 75/322 (23%), Positives = 110/322 (34%), Gaps = 59/322 (18%)

Query: 1319 APVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS-SPASP------SSASKEIG 1371
            AP+ FS    +  + GR  PD     H  ++ ++    H  S   P       SA+K  G
Sbjct: 3588 APLVFSGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAG 3647

Query: 1372 MPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQ 1431
               S    + A+T     P+   +  + P    GS  +P   +     G  P T      
Sbjct: 3648 CQSSSKDRSAAST-----PSKALKFPVHPRKAVGS-LAPGELARGTENGMKPAT------ 3695

Query: 1432 TEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESP-- 1489
                P+A  G ++ G  +         G G  PQP+       +++ P  PS PS SP  
Sbjct: 3696 ----PKAKPGPSSQGSGSPRP--GTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAP 3749

Query: 1490 ------------TFSP---------GKMGPRATAEFST-----QTPSPAPASDM---PRS 1520
                        T  P         G +GP+   E ST     Q P PA +  +    R+
Sbjct: 3750 ERLPARAQAKSCTKGPREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRA 3809

Query: 1521 PGAPTPSPMVAQGTQTPHR--PSTPRLVWQESSQEAPF-MVITLASDASSQTRMVHASAS 1577
            P AP   P   +   TP R  P+ P+   Q   +  P             + R+  A   
Sbjct: 3810 PSAPDKPPRTPRKQATPSRVLPTKPKPNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQ 3869

Query: 1578 TSPLCSPTETQPTTHGYSQTTP 1599
              PL  P +     HG     P
Sbjct: 3870 GRPLLRPPKRGTAVHGAEPAEP 3891



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 163/724 (22%), Positives = 230/724 (31%), Gaps = 123/724 (16%)

Query: 9    GGAGDGPLPPGGAGPGPGPGPG----PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG 64
            G  GD   P G  G      PG    P A   PS P G    P + +A + A    PGP 
Sbjct: 3222 GSPGD---PWGQEGEAKKDSPGERAKPRARSTPSNPDGAAT-PDSASATALADAGSPGPP 3277

Query: 65   ---PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRE-TRAQGPAGQ 120
               P P P P  G         EPL                TP HE+ ++ +R     G+
Sbjct: 3278 RTTPSPSPDPWAGG--------EPL-------------LQATPVHEACKDPSRDCHHCGK 3316

Query: 121  EADGP---RRTLQVDS--RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPI--C 173
                P   +R L V S  R     R P V P+ G           +   P     P+  C
Sbjct: 3317 RFPKPFKLQRHLAVHSPQRVYLCPRCPRVYPEHGELLAHLGGAHGLLERPELQHTPLYAC 3376

Query: 174  KTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNP--NPHLTQVKEWLCLNCQMQRALGMDMT 231
            +         + +F  C+ C+     +  F+   N HL   ++            G+   
Sbjct: 3377 ELCATVMRIIKKSF-ACSSCNYTFAKKEQFDRHMNKHLRGGRQPFAFR-------GVRRP 3428

Query: 232  TAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQP---------GSRQAETA 282
             AP  K++      AL       ++ +  P      G   P P         GS  A   
Sbjct: 3429 GAPGQKAR------ALEGTLPSKRRRVAMPGSAPGPGEDRPPPRGSSPILSEGSLPALLH 3482

Query: 283  RATSVPGPAQAAAPPEVGRVSPQPPQPTK----PSTAEPRPPAGEAPAKSATAVPAGLGA 338
              + V        P  + R       P +    PS  +  PP   +P  +A A   G  A
Sbjct: 3483 LCSEVAPSTTKGWPETLERPVDPVTHPIRGCELPSNHQECPPPSLSPFPAALADGRGDCA 3542

Query: 339  TEQTQEGLTGKLF-GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP 397
             +   E    +   G    LL QA  L +  P    +GQ A  K  P +VF+   +  G 
Sbjct: 3543 LDGALERPENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAP-LVFSGKRRAPGA 3601

Query: 398  KPLGSGPG---PGPAPGAKTEPGARMGPGSGP------GALPKTGGTTSPKHGRAEHQAA 448
            +   +             K    + M    GP      G+  K  G  S    R+     
Sbjct: 3602 RGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTP 3661

Query: 449  SKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKT 508
            SKA   P  +   +A+  L   EL  G++   N     T + +       + +P    KT
Sbjct: 3662 SKALKFP--VHPRKAVGSLAPGELARGTE---NGMKPATPKAKPGPSSQGSGSPRPGTKT 3716

Query: 509  EWLCLNCQTKRLLEGSLGEPTPLPP--PTSQQPPVGAPHRASGTSPLK---QKGPQGLGQ 563
                        L+      TP  P  P+    P   P RA   S  K   + G QG   
Sbjct: 3717 GGGSQPQPASGQLQSETAT-TPAKPSFPSRSPAPERLPARAQAKSCTKGPREAGEQGPHG 3775

Query: 564  PSGPLPAKASPLSTKASPLPSKASPQA------KPLRASEPSKTPSSVQEKKTRVPTKAE 617
              GP     S    K   +P  A  ++       P    +P +TP         +PTK +
Sbjct: 3776 SLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQATPSRVLPTKPK 3835

Query: 618  P----MPKPPP----------------------ETTPTPATPKVKSGVRRAEPATPVVKA 651
            P     P+PPP                      +  P    PK  + V  AEPA P    
Sbjct: 3836 PNSQNKPRPPPSEQRKAEPGHTQRKDRLGKAFPQGRPLLRPPKRGTAVHGAEPAEPHTHR 3895

Query: 652  VPEA 655
              EA
Sbjct: 3896 TAEA 3899



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 87/381 (22%), Positives = 121/381 (31%), Gaps = 64/381 (16%)

Query: 1278 LAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFS-TPTSSDSSGGRV 1336
            L   ED +KEK        +  P +    PL    SP+        S TPT  ++  GR 
Sbjct: 2222 LRIPEDSRKEK-------LWESPGRATSPPLAGAVSPSVAVRATGLSSTPTGDEAQAGRG 2274

Query: 1337 IPDVRVTQHFAKETQDPLKL---HSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGL 1393
            +P        A    +P ++   HSS  SPS+ ++   +   +G    A     P   G 
Sbjct: 2275 LPGPDPQSRGAPPHTNPDRMPRGHSS-YSPSNTAR---LGHREGQAVTAVPTEPPTLQGA 2330

Query: 1394 PRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKP 1453
                  P SPA  E     SS       +P T   G+        PS     GR      
Sbjct: 2331 G-----PDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSS 2385

Query: 1454 LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTP---- 1509
             +ASD +  +PQ  R  S+      PL P    +       K       ++  Q P    
Sbjct: 2386 -TASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPV 2444

Query: 1510 --------------------------SPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTP 1543
                                        APA   P +  A  P   +AQ  Q P + S  
Sbjct: 2445 TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPPRKKS-- 2502

Query: 1544 RLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVS 1603
                + S +E P        D S  T+   A  S   L +P           Q  PPS +
Sbjct: 2503 ---HRVSGKERP---NHSRGDPSHVTQPPPAQGSKEVLRAPGSPHS-----QQLHPPSPT 2551

Query: 1604 QLPPEPPGPPGFPRVPSAGAD 1624
            +   +   P   PR   A  D
Sbjct: 2552 EHEVDVKTPASKPRPDQARED 2572



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 99/391 (25%), Positives = 129/391 (32%), Gaps = 89/391 (22%)

Query: 17   PPGGAGPGPGP-----GPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG- 70
            PP   G GP       G    + K P  P      P  G + +T +P V  P  G G G 
Sbjct: 2324 PPTLQGAGPDSPACLEGEMGTSSKEPEDPG----TPETGRSGATKMPRVTCPSTGLGLGR 2379

Query: 71   -PGPGSTSRRLDPKEPLGNQRAASPTPK-------QASATTPGHES-PRETRAQGPAGQE 121
               P ST+       P  ++ A+  TP+            + G++  P  T      GQ 
Sbjct: 2380 TTAPSSTASDFQSDSPQSHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQA 2439

Query: 122  ADGPRRTLQVDSRTQRSGRSPSVSPDRGSTP-------TSPYSVPQIAPL-PSSTLC-PI 172
              GP  T +V + + RSG   S    R   P        SP ++P   PL P +  C P 
Sbjct: 2440 PHGPV-TCEVCAASFRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQPP 2498

Query: 173  CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232
             K S   S   +PN +     H            P     KE L                
Sbjct: 2499 RKKSHRVSGKERPNHSRGDPSH--------VTQPPPAQGSKEVL---------------R 2535

Query: 233  APRSKSQQQLHSPALSPAHSPAKQPLGK--PDQER------------------------- 265
            AP S   QQLH P+ +      K P  K  PDQ R                         
Sbjct: 2536 APGSPHSQQLHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDS 2595

Query: 266  ---SRGPGGPQPGSRQAETARATSV-PGPAQAAAPPEVGRVSP----QPPQPTKPSTAEP 317
               S G    + G  +    R  S+ P  A   +     R SP        P+   + E 
Sbjct: 2596 PSHSEGKSNKKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYAASPSHCLSVEG 2655

Query: 318  RPPA-GEAPAKSATAVPAGL-GATEQTQEGL 346
             P A GE P + AT  P  + GA E  QE L
Sbjct: 2656 GPEADGEQPPRLATLGPGVMEGAAETDQEAL 2686



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 91/344 (26%), Positives = 122/344 (35%), Gaps = 59/344 (17%)

Query: 3016 ELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTA--------FQQPRFQPPAPQYSAGS 3067
            +L   +L    TP G     P     P T + P A        FQ+P     +  Y++ S
Sbjct: 141  QLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPS 200

Query: 3068 --------GGPTQNGFPAHQAPTYPGPSTYPAPAFP-------PGASY---PAEPGLPNQ 3109
                    G P   G    Q  +YP      A ++P       PGA++   PAEP  P  
Sbjct: 201  ATPRPPAPGPPQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPE-PIP 259

Query: 3110 QAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV 3169
            +  RP G        P   S  FP PA   A   KP     AD+     TN  ++ +   
Sbjct: 260  KGSRPGG-------SPRGVSFQFPFPALHGAS-TKPFP---ADVAGHAFTNGPLVFAFHQ 308

Query: 3170 PMSSAPSETSYSGPAVSSGYE---------QGKVPEVPRAGDRGSVSQSP-----APTYP 3215
            P  + P E   +GPA     +         QG+   + R  D      SP     AP   
Sbjct: 309  PQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPF 368

Query: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGV- 3274
            SDS + SL + +P       D    T+   S+ P  QR  P     +      PG P   
Sbjct: 369  SDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLP--QRHFPGQAYRASGVDTSPGPPDTE 426

Query: 3275 LDGPTLPCCYARGEEESEEDSYDPRGKGGHL---RSMESNGRPA 3315
            L  P  P        +     Y P   GG L   RSM  NG+P+
Sbjct: 427  LAAPGPPPARLPQLWDPTAAPY-PTPPGGPLAATRSMFFNGQPS 469



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 166/741 (22%), Positives = 228/741 (30%), Gaps = 182/741 (24%)

Query: 5    VSLEGGA-GDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGP 63
            +S+EGG   DG  PP  A  GPG   G       +  AG            T     PG 
Sbjct: 2651 LSVEGGPEADGEQPPRLATLGPGVMEGAAETDQEALCAG-----------ETGAQKPPG- 2698

Query: 64   GPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEAD 123
                          R L P    G      PT  Q  A+  G   PRET+A G   +   
Sbjct: 2699 -------------DRMLCPGRMDGAALGEQPTG-QKGASARGFWGPRETKALGVCKESGS 2744

Query: 124  GPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
             P      +  ++   RS     +  + P  P   P+ +  P+ +    C    L   P 
Sbjct: 2745 EP-----AEDSSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSC----LQGLPD 2795

Query: 184  QPNFNTCTQ--------------------CHNKVCNQCGFNPNPHLTQV----------- 212
             P+     Q                      ++V     F P   LT+            
Sbjct: 2796 NPDTQGGVQGPEGPTPDASGSSAKDPPSLFDDEVSFSQLFPPGGRLTRKRNPHVYGKRCE 2855

Query: 213  KEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPA---KQPLGKPDQE----- 264
            K  L L  Q     G D T  P         S +L   H      + P G P+       
Sbjct: 2856 KPVLPLPTQPSFEEGGDPTLGPARLPTDLSDSSSLCLCHEDPWEDEDPAGLPESFLLDGF 2915

Query: 265  -RSRGPGGPQ--PG--------SRQAETARATS-VPGPAQAAAPPEV--------GRVSP 304
              SR PG     PG        SR+A   +  S  P   +  A PE+        G   P
Sbjct: 2916 LNSRVPGIDPWAPGLSLWALEPSREAGAEKLPSHCPEDDRPEAIPELHMVPAAWRGLEMP 2975

Query: 305  QPPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGK--LFGLGASLLTQ 360
             P   +  S  +  P PP+ E                E+   GL G   L  L A+    
Sbjct: 2976 APADDSSSSLGDVSPEPPSLER---------------ERCDGGLPGNTHLLPLRATDFEV 3020

Query: 361  ASTLMSVQ------PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKT 414
             ST   +Q      P  D  G P PS     + F   +   GP+              +T
Sbjct: 3021 LSTKFEMQDLCFLGPFEDPVGLPGPSF----LDFEGTASSQGPQ------------SRRT 3064

Query: 415  EPGARMGPGSGPGALPKTGGTTSPKH----------GRAEHQAASKAAAKPKTMPKERAI 464
            E  A  G   G G  P  G   S K           G  +    +   A P T       
Sbjct: 3065 EEAAGAGRAQGRGR-PAKGRRASYKCKVCFQRFRSLGELDLHKLAHTPAPPPT------- 3116

Query: 465  CPLCQAELNVGSK-------------SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWL 511
            C +C  E   GS+             S A    C  C  +V ++  +N   HL E     
Sbjct: 3117 CYMC-VERRFGSRELLRGHLQERHAQSKAGPWACGMCLKEVADVWMYNE--HLREHAVRF 3173

Query: 512  CLNCQTKRLLEGSLGEPTPLPPPTSQQPPVG-APHRASGTSPLKQKGPQGLGQPSGPLPA 570
                Q +R    SLG+   LP        V    +  +  +P   +G +  G+ +G   +
Sbjct: 3174 ARRGQARR----SLGD---LPGGLEGSSAVAHLLNSITEPAPKHHRGKRSAGKAAG---S 3223

Query: 571  KASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTP 630
               P   +          +AKP   S PS    +           A+     PP TTP+P
Sbjct: 3224 PGDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGSPGPPRTTPSP 3283

Query: 631  ATPKVKSGVRRAEPATPVVKA 651
             +P   +G      ATPV +A
Sbjct: 3284 -SPDPWAGGEPLLQATPVHEA 3303



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 71/273 (26%), Positives = 96/273 (35%), Gaps = 42/273 (15%)

Query: 3675 GRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA 3734
            G  EA   +Q    P    + QP      E   PS    A   ++  K+GS Q   G + 
Sbjct: 47   GAREAGGQAQAMELP----EAQPRQARDGELKPPSLRGQA-PSSTPGKRGSPQTPPGRSP 101

Query: 3735 LQSKAEPQAQPQLQGRQAAPGPQQS--QSPSSRQIPS-GAASRQPQTQQQQ-------QG 3784
            LQ      A  +L GR     PQ+      SSR  P+       PQ +  Q       QG
Sbjct: 102  LQ------APSRLAGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQG 155

Query: 3785 LGL-------------QPPQQALTQARLQQQ---SQPTTRGSAPAASQPAGKPQPGPSTA 3828
             G              QP  + L   R  Q+   S  +T  ++P+A+     P P  S  
Sbjct: 156  PGTGAPLRPGLPRTEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRG 215

Query: 3829 TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ- 3887
            T P   G     Q +G+     A +          P   P  +  G+RPGG+P   + Q 
Sbjct: 216  TSPLQPGSYPEYQASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQF 275

Query: 3888 --PGADGESVFSKILPGGAAEQAGKLTEAVSAF 3918
              P   G S  +K  P   A  A      V AF
Sbjct: 276  PFPALHGAS--TKPFPADVAGHAFTNGPLVFAF 306



 Score = 42.0 bits (97), Expect = 0.012
 Identities = 96/500 (19%), Positives = 145/500 (29%), Gaps = 78/500 (15%)

Query: 3440 SSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKP----------SSLSMA 3489
            S R+ +     G+ L   D     +GY+++  + E  Q  G  P          +S    
Sbjct: 2397 SHRNASHQTPQGDPLGPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVTCEVCAASFRSG 2456

Query: 3490 HSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPR 3549
                R   R       +P  P     PA  PL P    C         P  + H   G  
Sbjct: 2457 PGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQKCQP-------PRKKSHRVSGKE 2509

Query: 3550 AHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQK 3609
               + R      D SH                     P     +  R  G    S  SQ+
Sbjct: 2510 RPNHSRG-----DPSHVTQPP----------------PAQGSKEVLRAPG----SPHSQQ 2544

Query: 3610 RGPARHSYHDYD-EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRH-----SGRHTGEEPG 3663
              P   + H+ D + P     P        H    E R G   R      S  H+  +  
Sbjct: 2545 LHPPSPTEHEVDVKTPASKPRPDQAREDELHPKQAEKREGRRWRREPTVDSPSHSEGKSN 2604

Query: 3664 RRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHA-SDSK 3722
            ++  K   R L      P S    +     +  P   S A  + PS   S      +D +
Sbjct: 2605 KKRGKLRGRRLREESILPVSADVISDGRGSRPSPAMASYA--ASPSHCLSVEGGPEADGE 2662

Query: 3723 KGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQ 3782
            +  R A  GP  ++  AE   +    G   A  P   +     ++   A   QP  Q+  
Sbjct: 2663 QPPRLATLGPGVMEGAAETDQEALCAGETGAQKPPGDRMLCPGRMDGAALGEQPTGQKGA 2722

Query: 3783 QGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQT 3842
               G   P++  T+A                          G    +G +PA       +
Sbjct: 2723 SARGFWGPRE--TKAL-------------------------GVCKESGSEPAEDSSRAHS 2755

Query: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPG 3902
               +G  +       P   P     PA     +   G P  P  Q G  G    +    G
Sbjct: 2756 RSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQGPEGPTPDASG 2815

Query: 3903 GAAEQAGKLTEAVSAFGKKF 3922
             +A+    L +   +F + F
Sbjct: 2816 SSAKDPPSLFDDEVSFSQLF 2835



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 76/308 (24%), Positives = 105/308 (34%), Gaps = 79/308 (25%)

Query: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGLPR-------GYMT-PASPAGSERS----- 1409
            P  A +  G+  S GP      A  P PA LP+        Y T P  P  + RS     
Sbjct: 407  PGQAYRASGVDTSPGPPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLAATRSMFFNG 466

Query: 1410 -PSPSS-----------------TAHSYGHS-------PTTANYGSQTEDLPQAPSGLAA 1444
             PSP                   TA    H        P  A  G + +   Q   G A 
Sbjct: 467  QPSPGQRLCLPQSAPLPWPQVLPTARPSPHGMEMLSRLPFPAG-GPEWQGGSQGALGTAG 525

Query: 1445 AGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP-----SSPSESPTFSPGKMGPR 1499
                 REK  +    +GG+P     ++Y   + P   P     + P  SP  +P    PR
Sbjct: 526  KTPGPREKLPAVRSSQGGSP---ALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPR 582

Query: 1500 ATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
                  +++P P+PA++   S    + SPM    + +P  PS+     +ES    P    
Sbjct: 583  VVGASPSESPLPSPATNTAGST-CSSLSPM----SSSPANPSS-----EESQLPGP---- 628

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS--VSQLPPEPPGPPGFPR 1617
                        +  SA   P   PT  Q T   +    PP    +   PEP     FP 
Sbjct: 629  ------------LGPSAFFHP---PTHPQETGSPFPSPEPPHSLPTHYQPEPAKAFPFP- 672

Query: 1618 VPSAGADG 1625
                GA+G
Sbjct: 673  ADGLGAEG 680



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 70/281 (24%), Positives = 98/281 (34%), Gaps = 30/281 (10%)

Query: 1390 PAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAA 1449
            P   PRG   P      +     SS  H            ++T    +   G A A    
Sbjct: 2    PGERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELP 61

Query: 1450 REKPLSASDGEGGTPQPSRAYSYFASSSP-----PLSPSSPSESPTFSPGKMGPRATAE- 1503
              +P  A DGE    +P        SS+P     P +P  P  SP  +P ++  RA    
Sbjct: 62   EAQPRQARDGE---LKPPSLRGQAPSSTPGKRGSPQTP--PGRSPLQAPSRLAGRAEGSP 116

Query: 1504 ---------FSTQTPSPAPASDMPRSPGAPTPSPMVAQG--TQTPHRPSTPRLVWQESSQ 1552
                      S   P+     + P+   A  P     QG  T  P RP  PR   Q +++
Sbjct: 117  PQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176

Query: 1553 EAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGP 1612
            E  F         SS T   + S S +P   P    P + G S   P S  +   +  G 
Sbjct: 177  ELGFH-RCFQEPPSSFTSTNYTSPSATPR-PPAPGPPQSRGTSPLQPGSYPEY--QASGA 232

Query: 1613 PGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSR 1653
              +P  P+A    P A   +G  PAE   + + S   G+ R
Sbjct: 233  DSWP--PAAENSFPGA--NFGVPPAEPEPIPKGSRPGGSPR 269



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 43/144 (29%), Positives = 60/144 (41%), Gaps = 18/144 (12%)

Query: 3790 PQQALTQARLQQQSQPTTRGSAPA--------ASQPAGKPQPGPSTATG--PQPAGPPRA 3839
            P++A+      + ++ T  G  PA        +SQ +G P+PG  T  G  PQPA     
Sbjct: 3671 PRKAVGSLAPGELARGTENGMKPATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQ 3730

Query: 3840 EQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ--PGADGESVFS 3897
             +T  +      P +  AP+  PA     +  K G R  G  G P G   P   GES   
Sbjct: 3731 SETATTPAKPSFPSRSPAPERLPARAQAKSCTK-GPREAGEQG-PHGSLGPKEKGESSTK 3788

Query: 3898 K---ILPGGA-AEQAGKLTEAVSA 3917
            +    +PG A +E  G    A SA
Sbjct: 3789 RKKGQVPGPARSESVGSFGRAPSA 3812



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 53/187 (28%), Positives = 72/187 (38%), Gaps = 35/187 (18%)

Query: 7    LEGGAGDGPLPPGGAGPGPGPGP---GPGAGKPPSAPAGGGQ-LPAAGAARS-TAVPPVP 61
            L  G  +G  P   A P   PGP   G G+ +P +   GG Q  PA+G  +S TA  P  
Sbjct: 3683 LARGTENGMKP---ATPKAKPGPSSQGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAK 3739

Query: 62   GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP---A 118
               P   P P       RL             P   QA + T G   PRE   QGP    
Sbjct: 3740 PSFPSRSPAP------ERL-------------PARAQAKSCTKG---PREAGEQGPHGSL 3777

Query: 119  GQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDL 178
            G +  G   T +   +     RS SV    G  P++P   P+  P   +T   +  T   
Sbjct: 3778 GPKEKGESSTKRKKGQVPGPARSESVG-SFGRAPSAPDKPPR-TPRKQATPSRVLPTKPK 3835

Query: 179  TSTPSQP 185
             ++ ++P
Sbjct: 3836 PNSQNKP 3842



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 108/444 (24%), Positives = 139/444 (31%), Gaps = 105/444 (23%)

Query: 1300 PMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS 1359
            P  +   PL PG+ P   A+      P + +S  G                 +P+   S 
Sbjct: 211  PQSRGTSPLQPGSYPEYQASGADSWPPAAENSFPG-------ANFGVPPAEPEPIPKGSR 263

Query: 1360 P-ASPSSASKEIGMPFSQGPGT---PATTAVAPCPAG-------LPRGYMT-------PA 1401
            P  SP   S +   P   G  T   PA  A      G        P+G          PA
Sbjct: 264  PGGSPRGVSFQFPFPALHGASTKPFPADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPA 323

Query: 1402 SPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAR----------- 1450
             P  ++ +PSP      Y   P   N  S   DL  A S   AA  A R           
Sbjct: 324  YPLPTQPAPSP---LPCYQGQPGGLNRHS---DLSGALSSPGAAHSAPRPFSDSLHKSLT 377

Query: 1451 ----EKPLSASDGEGGT-------PQ---PSRAYSYFASSSPPLSPSSPSESPTFSPGKM 1496
                E+P SA DG G T       PQ   P +AY      + P  P +   +P   P ++
Sbjct: 378  KILPERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPGPPPARL 437

Query: 1497 ----------------GPRATAE--FSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQ-TP 1537
                            GP A     F    PSP     +P+S  AP P P V    + +P
Sbjct: 438  PQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQS--APLPWPQVLPTARPSP 495

Query: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSP------LCSPTETQPTT 1591
            H          E     PF          SQ  +  A  +  P      + S     P  
Sbjct: 496  H--------GMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAVRSSQGGSPAL 547

Query: 1592 HGYSQTTPP-------SVSQLPPEPPGPPGFPRVPSAGA---DGPLALYGWGALPAENIS 1641
              Y+  T P        V+Q    P G P  P     GA   + PL         +   S
Sbjct: 548  FTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPATNTAGSTCSS 607

Query: 1642 LCRISSVPGTSRVE----PGPRTP 1661
            L  +SS P     E    PGP  P
Sbjct: 608  LSPMSSSPANPSSEESQLPGPLGP 631



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 51/242 (21%), Positives = 77/242 (31%), Gaps = 13/242 (5%)

Query: 3641 SAKEHRHGDHGRHSGRHTGEE----PGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQ 3696
            S K    G  GR +  H  E+      +  +  H    G      H   ++ PA  +   
Sbjct: 3593 SGKRRAPGARGRCAPDHFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQS-- 3650

Query: 3697 PGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGP 3756
                SS + S  S  S A       +K        P  L    E   +P     +  P  
Sbjct: 3651 ----SSKDRSAASTPSKALKFPVHPRKAVGSL--APGELARGTENGMKPATPKAKPGPSS 3704

Query: 3757 QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQ 3816
            Q S SP       G +  QP + Q Q      P + +        +  P    +      
Sbjct: 3705 QGSGSPRPGTKTGGGSQPQPASGQLQSETATTPAKPSFPSRSPAPERLPARAQAKSCTKG 3764

Query: 3817 PAGKPQPGPSTATGPQPAGPPRAEQTNGS-KGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
            P    + GP  + GP+  G    ++  G   G A++   G   +A  AP   P   +  A
Sbjct: 3765 PREAGEQGPHGSLGPKEKGESSTKRKKGQVPGPARSESVGSFGRAPSAPDKPPRTPRKQA 3824

Query: 3876 RP 3877
             P
Sbjct: 3825 TP 3826



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 106/447 (23%), Positives = 145/447 (32%), Gaps = 97/447 (21%)

Query: 3515 RPAGGPLPP-GGDTCP-QFCSSHSMPDVQEHVKDGPRAHAYK--REEGYILDDSHCVVSD 3570
            RP G P P   GD  P Q  SS   P       + P     K  RE G            
Sbjct: 5    RPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAG----------GQ 54

Query: 3571 SEAYHLGQEETDWFDKPRDARSDRFRHHG--GHAVSSSSQKRG-------------PARH 3615
            ++A  L + +      PR AR    +     G A SS+  KRG             P+R 
Sbjct: 55   AQAMELPEAQ------PRQARDGELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRL 108

Query: 3616 SYHDYDEPPEEGLW---------PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG--R 3664
            +      PP+  +            DE        A +    D  +  G      PG  R
Sbjct: 109  AGRAEGSPPQRYILGIASSRTKPTLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPR 168

Query: 3665 RAAKPHARDLGRHE----------ARPHSQPSSAPAMPKKGQPG-------YPSSAEYSQ 3707
              A+P A +LG H           +  ++ PS+ P  P  G P         P S    Q
Sbjct: 169  TEAQPAAEELGFHRCFQEPPSSFTSTNYTSPSATPRPPAPGPPQSRGTSPLQPGSYPEYQ 228

Query: 3708 PSRASSAYHHASDSKKGSRQA--HSGPAALQSKAEPQAQPQ----------LQGRQAAPG 3755
             S A S    A +S  G+      + P  +   + P   P+          L G    P 
Sbjct: 229  ASGADSWPPAAENSFPGANFGVPPAEPEPIPKGSRPGGSPRGVSFQFPFPALHGASTKPF 288

Query: 3756 PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQ-------------ARLQQQ 3802
            P      +    P   A  QPQ    ++ +G  P     TQ               L + 
Sbjct: 289  PADVAGHAFTNGPLVFAFHQPQGAWPEEAVGTGPAYPLPTQPAPSPLPCYQGQPGGLNRH 348

Query: 3803 SQPTTRGSAPAASQPAGKPQPGP--STATGPQPAGPPRAEQTNGSK--GTAKAPQQGRAP 3858
            S  +   S+P A+  A +P       + T   P  PP A+   GS     +  PQ+    
Sbjct: 349  SDLSGALSSPGAAHSAPRPFSDSLHKSLTKILPERPPSAQDGLGSTRGPPSSLPQRHFPG 408

Query: 3859 QAQPAPG----PGPAGVKAGARPGGTP 3881
            QA  A G    PGP   +  A PG  P
Sbjct: 409  QAYRASGVDTSPGPPDTELAA-PGPPP 434



 Score = 38.9 bits (89), Expect = 0.10
 Identities = 58/234 (24%), Positives = 80/234 (34%), Gaps = 30/234 (12%)

Query: 3681 PHSQPSSAPAMPKKGQPGY--PSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK 3738
            P     +AP  P    P    P++A Y  P     A   A+ S   + Q   G      +
Sbjct: 422  PPDTELAAPGPPPARLPQLWDPTAAPYPTPPGGPLA---ATRSMFFNGQPSPGQRLCLPQ 478

Query: 3739 AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQP-PQQALTQA 3797
            + P   PQ+    A P P   +  S    P+G    Q  +Q      G  P P++ L   
Sbjct: 479  SAPLPWPQVLPT-ARPSPHGMEMLSRLPFPAGGPEWQGGSQGALGTAGKTPGPREKLPAV 537

Query: 3798 RLQQQ---------------SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---PPRA 3839
            R  Q                +QP   G A     P G P   P    G  P+    P  A
Sbjct: 538  RSSQGGSPALFTYNGMTDPGAQPLFFGVAQPQVSPHGTPSLPPPRVVGASPSESPLPSPA 597

Query: 3840 EQTNGSKGTAKAPQQGRA--PQAQPAPGPGPAGVKAGARPGGTP---GAPAGQP 3888
              T GS  ++ +P       P ++ +  PGP G  A   P   P   G+P   P
Sbjct: 598  TNTAGSTCSSLSPMSSSPANPSSEESQLPGPLGPSAFFHPPTHPQETGSPFPSP 651



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 60/219 (27%), Positives = 76/219 (34%), Gaps = 36/219 (16%)

Query: 3683 SQPSSAPAMPKKGQPGYPS-----SAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            +QP+ +P    +GQPG  +     S   S P  A SA    SDS       H     +  
Sbjct: 328  TQPAPSPLPCYQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDS------LHKSLTKILP 381

Query: 3738 KAEPQAQPQLQGRQAAPGP-QQSQSPSSRQIPSGAASRQ--PQTQQQQQGLGLQPPQQAL 3794
            +  P AQ  L   +  P    Q   P      SG  +    P T+    G    PP    
Sbjct: 382  ERPPSAQDGLGSTRGPPSSLPQRHFPGQAYRASGVDTSPGPPDTELAAPG----PPP--- 434

Query: 3795 TQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAPQ 3853
              ARL Q   PT        + P   P  GP  AT      G P   Q      +A  P 
Sbjct: 435  --ARLPQLWDPT--------AAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPW 484

Query: 3854 QGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADG 3892
                PQ  P   P P G++  +R     G P  Q G+ G
Sbjct: 485  ----PQVLPTARPSPHGMEMLSRLPFPAGGPEWQGGSQG 519



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 133/590 (22%), Positives = 196/590 (33%), Gaps = 155/590 (26%)

Query: 3045 PSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEP 3104
            P GP+AF    F PP      GS  P+    P H  PT+  P   PA AFP    +PA+ 
Sbjct: 628  PLGPSAF----FHPPTHPQETGSPFPSPE--PPHSLPTHYQPE--PAKAFP----FPAD- 674

Query: 3105 GLPNQQAFR-----PTGHYAGQT-------------PMPTTQSTLFPVPADSRAPLQKPR 3146
            GL  + AF+     P  H   +              P PT   +L     D    L   R
Sbjct: 675  GLGAEGAFQCLEETPFPHEGPEVGRGGLQGFPRAPPPYPTHHFSLSSASLDQLDVLLTCR 734

Query: 3147 Q-----TSLA-----------------DLEQKVPTNYEVIASPVVPMSSAPSET---SYS 3181
            Q     +SLA                 D  Q+ P    + + P  P   A +     S++
Sbjct: 735  QCDRNYSSLAAFLAHRQFCGLLLARAKDGHQRSPGPPGLPSPPAAPRVPADAHAGLLSHA 794

Query: 3182 GPAVSSGYEQGKVPEVP-RAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISEL 3240
               + +G  Q +  + P R G   S++ +P P   SD     +E +   + ++ + ++ +
Sbjct: 795  KTFLLAGDAQAEGKDDPLRTGFLPSLAATPFPLPASD---LDMEDDAKLDSLITEALNGM 851

Query: 3241 TKDSTSTAPDSQRL------EPLGP--GSSGRPGKE-----------PGEPGVLDGPTLP 3281
               S +   DS  +      EP GP   SSG P K            P  P     P  P
Sbjct: 852  EYQSDNPEIDSSFIDVFADEEPSGPRGPSSGHPLKSKAGVTPESKAPPPLPAATPDPQTP 911

Query: 3282 -----CCYARGEEESEEDSYDP-------------RGK-----------GGHLRSMESNG 3312
                  C ARG  ++      P             RGK           GG      S G
Sbjct: 912  RPGDRGCPARGRPKTRSLGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGG 971

Query: 3313 -------RPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQ-- 3363
                   RP      G+       R     PG      P    A A     RS  R++  
Sbjct: 972  GGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLP 1031

Query: 3364 ---------------GME------QKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGR 3402
                           G E      Q+ ++    + A + E D    PPP        RGR
Sbjct: 1032 PRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEED--EQPPPRGPGFRGRRGR 1089

Query: 3403 ---KFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDF 3459
               + + E+T G +++  E QK    + ++A       GG      P    G +      
Sbjct: 1090 GEKRKEVELTQGPRED--EPQKPRKAARQEA-------GGDGAPANPEEPGGSR-PGPGR 1139

Query: 3460 SGWGKGYEREREAVERLQKAGPKPSSLSMAHSR--VRPPMRSQASEEESP 3507
            S   +G  R  E     ++ GPK +       +  ++ P  ++ SEE  P
Sbjct: 1140 SPQARGPSRSLETGAAAREGGPKCADRPSVAPKDPLQVPTNTETSEETRP 1189



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 136/621 (21%), Positives = 189/621 (30%), Gaps = 129/621 (20%)

Query: 21   AGPG-PGPGP----GPGAGKPPSAPAGGGQLPAAGAARS--------TAVPPVPGPGPGP 67
            AG G PGP P     P    P   P G      +  AR         TAVP  P    G 
Sbjct: 2271 AGRGLPGPDPQSRGAPPHTNPDRMPRGHSSYSPSNTARLGHREGQAVTAVPTEPPTLQGA 2330

Query: 68   GPG------------------PGPGSTSRRLDPKEP--------LGNQRAASPTPKQASA 101
            GP                   PG   T R    K P        LG  R  +P+   +  
Sbjct: 2331 GPDSPACLEGEMGTSSKEPEDPGTPETGRSGATKMPRVTCPSTGLGLGRTTAPSSTASDF 2390

Query: 102  TTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQI 161
             +   +S R    Q P G    GP+   Q     ++   S      +G  P  P +    
Sbjct: 2391 QSDSPQSHRNASHQTPQGDPL-GPQDLKQRSRGYKKKPASTENGQWKGQAPHGPVT---- 2445

Query: 162  APLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLT---QVKEWLCL 218
                    C +C  S      S P  +      ++        P+P      Q  E L  
Sbjct: 2446 --------CEVCAAS----FRSGPGLSRHKARKHRPHPGAPAEPSPAALPAQQPLEPLAQ 2493

Query: 219  NCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP-AKQPLGKPDQERSRGPGGPQPGSR 277
             CQ  R     ++   R    +   S    P  +  +K+ L  P    S+    P P   
Sbjct: 2494 KCQPPRKKSHRVSGKERPNHSRGDPSHVTQPPPAQGSKEVLRAPGSPHSQQLHPPSPTEH 2553

Query: 278  QAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAE-PRPPAGEAPAKSATAVPAGL 336
            + +     S P P QA            P Q  K       R P  ++P+ S        
Sbjct: 2554 EVDVKTPASKPRPDQARED------ELHPKQAEKREGRRWRREPTVDSPSHS-------- 2599

Query: 337  GATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAG 396
                   EG + K  G       +  +++ V  +  + G+   S+ +P +    AS  A 
Sbjct: 2600 -------EGKSNKKRGKLRGRRLREESILPVSADVISDGR--GSRPSPAM----ASYAAS 2646

Query: 397  PKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPK 456
            P    S  G   A G +    A +GPG   GA               + +A        +
Sbjct: 2647 PSHCLSVEGGPEADGEQPPRLATLGPGVMEGA------------AETDQEALCAGETGAQ 2694

Query: 457  TMPKERAICP-----LCQAELNVGSKSPAN---YNTCTTCRLQVCNLCGFNPTPHLVEKT 508
              P +R +CP         E   G K  +    +    T  L VC   G  P        
Sbjct: 2695 KPPGDRMLCPGRMDGAALGEQPTGQKGASARGFWGPRETKALGVCKESGSEPAED----- 2749

Query: 509  EWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS--------PLKQKGPQG 560
                 +    R  EG   E TP   P        +P  ++ +S        P  Q G QG
Sbjct: 2750 ----SSRAHSRSEEGVWEENTPPLGPLGFPETSSSPADSTTSSCLQGLPDNPDTQGGVQG 2805

Query: 561  LGQPSGPLPAKASPLSTKASP 581
               P GP P  AS  S K  P
Sbjct: 2806 ---PEGPTP-DASGSSAKDPP 2822



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 38/165 (23%), Positives = 54/165 (32%), Gaps = 18/165 (10%)

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
            P     LQ RQ A  P     P          + +   +   Q   ++ P+    QAR  
Sbjct: 12   PTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEAQPRQARDG 71

Query: 3801 QQSQPTTRGSAPAA---------SQPAGKPQPGPSTATGPQPAGPPR-------AEQTNG 3844
            +   P+ RG AP++         + P   P   PS   G     PP+       + +T  
Sbjct: 72   ELKPPSLRGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSPPQRYILGIASSRTKP 131

Query: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPG--GTPGAPAGQ 3887
            +        Q  A Q      P   G  A  RPG   T   PA +
Sbjct: 132  TLDETPENPQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEAQPAAE 176



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 41/161 (25%), Positives = 58/161 (36%), Gaps = 24/161 (14%)

Query: 3739 AEPQAQPQLQGRQAAPGPQQ-SQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQA 3797
            A+PQ  P   G  + P P+    SPS   +PS A +    T      +   P   +  ++
Sbjct: 566  AQPQVSPH--GTPSLPPPRVVGASPSESPLPSPATNTAGSTCSSLSPMSSSPANPSSEES 623

Query: 3798 RLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA---PQQ 3854
            +L     P+     P   Q  G P P P          PP +  T+     AKA   P  
Sbjct: 624  QLPGPLGPSAFFHPPTHPQETGSPFPSPE---------PPHSLPTHYQPEPAKAFPFPAD 674

Query: 3855 G-------RAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            G       +  +  P P  GP   + G +  G P AP   P
Sbjct: 675  GLGAEGAFQCLEETPFPHEGPEVGRGGLQ--GFPRAPPPYP 713



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 31/103 (30%), Positives = 42/103 (40%), Gaps = 13/103 (12%)

Query: 2260 RYPAPSRFPI---ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTP 2316
            R  APS  P    +   PP   P+      A +A G+  P R  + + ++R +P    TP
Sbjct: 79   RGQAPSSTPGKRGSPQTPPGRSPLQAPSRLAGRAEGSP-PQRYILGIASSRTKPTLDETP 137

Query: 2317 AAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
                       P   A Q P  D   G G+GA  RPG  + EA
Sbjct: 138  EN---------PQLEAAQLPEVDTPQGPGTGAPLRPGLPRTEA 171



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 65/258 (25%), Positives = 83/258 (32%), Gaps = 51/258 (19%)

Query: 3661 EPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASD 3720
            EPG  A +PH R     EA        AP +  +G    P  A +  P  AS + H A  
Sbjct: 1751 EPGT-ADQPH-RGAPAPEAFGSPAVHLAPDLAFQGDGAPPLDATW--PFGASPS-HAAQG 1805

Query: 3721 SKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAP-GPQQSQSPSSRQ-----IPSGAASR 3774
               G    H  P A         +P  +G + AP G     +P  R+     +PS A   
Sbjct: 1806 HSAGRAGGHLHPTA--------GRPGFEGNEFAPAGASSLTAPRGREAWLVPVPSPACVS 1857

Query: 3775 QPQTQQQQQGLGLQPPQQ-----------------ALTQARLQQQSQP----------TT 3807
                 ++ Q   L PP +                  L +     QS P          T 
Sbjct: 1858 NTHPSRRSQDPALSPPIRQLQLPGPGVAKSKDGILGLQELTPAAQSPPRVNPSGLEGGTV 1917

Query: 3808 RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG----TAKAPQQGRAPQAQPA 3863
             G   A     G P  G    T P  AG     + +G  G      K   QG A Q QP 
Sbjct: 1918 EGGKVACGPAQGSPG-GVQVTTLPAVAGHQLGLEADGHWGLLGQAEKTQGQGTANQLQPE 1976

Query: 3864 PGPGPAGVKAGARPGGTP 3881
             G  P G    A    +P
Sbjct: 1977 NGVSPGGTDNHASVNASP 1994



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 53/229 (23%), Positives = 77/229 (33%), Gaps = 40/229 (17%)

Query: 1390 PAGLPRGYMTPASPAGSERSPSPSSTA-HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRA 1448
            P G        ASP  +   P+  +        S    +   + E  P  PS    +   
Sbjct: 1981 PGGTDNHASVNASPKTALTGPTEGAVLLEKCKGSRAAMSLQEEAEPTPSPPSPNRESLAL 2040

Query: 1449 AREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQT 1508
            A     S S  EG TP+         +SSP L+       P  + G     +  + +   
Sbjct: 2041 ALTAAHSRSGSEGRTPE--------RASSPGLN------KPLLATGDSPAPSVGDLAACA 2086

Query: 1509 PSPAPASDMPRSPGA-----PTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLAS 1563
            PSP  A+ MP S G      P  SP  AQG      P++P                    
Sbjct: 2087 PSPTSAAHMPCSLGPLPREDPLTSPSRAQGGLGGQLPASPS-----------------CR 2129

Query: 1564 DASSQTRMVHASASTSPLCSPTETQPTTH---GYSQTTPPSVSQLPPEP 1609
            D     +++  S + +PL      Q TT      S   PPS++  P +P
Sbjct: 2130 DPPGPQQLLACSPAWAPLEEADGVQATTDTGAEDSPVAPPSLTTSPCDP 2178



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 54/200 (27%), Positives = 75/200 (37%), Gaps = 30/200 (15%)

Query: 3718 ASDSKKGSRQAHSGPAALQSKA----EPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS 3773
            A +   G R   SG   L+SKA    E +A P L    A P PQ  + P  R  P   A 
Sbjct: 869  ADEEPSGPRGPSSGHP-LKSKAGVTPESKAPPPLPA--ATPDPQTPR-PGDRGCP---AR 921

Query: 3774 RQPQTQQQQQGLGLQP-----PQQALTQARLQQ--------QSQPTTRGSAPAASQPAGK 3820
             +P+T+     LGL P     P Q   Q R +Q         S     GS       A  
Sbjct: 922  GRPKTRS----LGLAPTEADAPSQGRQQRRGKQLKLFRKDLDSGGAAEGSGSGGGGRASG 977

Query: 3821 PQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
             +P  +   G +P  PPR  +       ++A    R P+A   P    +  +    P   
Sbjct: 978  LRPRRNDGLGERP--PPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSRRRRLPPRKD 1035

Query: 3881 PGAPAGQPGADGESVFSKIL 3900
            P     + GA G+ +  KI+
Sbjct: 1036 PRKRKARGGAWGKELILKIV 1055



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 42/176 (23%), Positives = 58/176 (32%), Gaps = 27/176 (15%)

Query: 1822 GTAQSIGLKPGPVPEPGAEPHRATPAELRSH-----ALPGARKPHTVVVQMGEGTAGTVT 1876
            G A  +  +P P P P    ++  P  L  H     AL      H+      +    ++T
Sbjct: 321  GPAYPLPTQPAPSPLPC---YQGQPGGLNRHSDLSGALSSPGAAHSAPRPFSDSLHKSLT 377

Query: 1877 TLLPEEPAGALDLTGMR--PESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPP 1934
             +LPE P  A D  G    P S L         P  +        +P  P+  +A   PP
Sbjct: 378  KILPERPPSAQDGLGSTRGPPSSLP----QRHFPGQAYRASGVDTSPGPPDTELAAPGPP 433

Query: 1935 GQSSSPFYGPRDPEPPEPP--------TYRAQGVVGPG-----PHEEQRPYPQGLP 1977
                   + P     P PP        +    G   PG     P     P+PQ LP
Sbjct: 434  PARLPQLWDPTAAPYPTPPGGPLAATRSMFFNGQPSPGQRLCLPQSAPLPWPQVLP 489



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 120/515 (23%), Positives = 175/515 (33%), Gaps = 137/515 (26%)

Query: 404  PGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERA 463
            PG  P PG    P     P    G+LP      S         A S     P+T+  ER 
Sbjct: 3452 PGSAPGPGEDRPPPRGSSPILSEGSLPALLHLCS-------EVAPSTTKGWPETL--ERP 3502

Query: 464  ICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEG 523
            + P+       G + P+N+  C    L        +P P  +        +C     LE 
Sbjct: 3503 VDPVTHPIR--GCELPSNHQECPPPSL--------SPFPAALADGRG---DCALDGALER 3549

Query: 524  SLGEPTP-LPPPTSQQP-PVGAPHRASGT---------SPL----KQKGPQGLGQPSGPL 568
               E +P  P P  QQ  P+GA     G          +PL    K++ P   G+   P 
Sbjct: 3550 PENEASPGSPGPLLQQALPLGASLPRPGARGQDAEGKRAPLVFSGKRRAPGARGR-CAPD 3608

Query: 569  PAKASPLSTK-----ASPLPSKASPQAKPLR--ASEPSKTPSSVQEKKTR-VPTKAEPMP 620
              +   L  K     +S + S+  P+    +  A++P+   SS +++     P+KA   P
Sbjct: 3609 HFQEDHLLQKEKEVSSSHMVSEGGPRGTFHKGSATKPAGCQSSSKDRSAASTPSKALKFP 3668

Query: 621  KPPPETTPTPATPKVKSGVRRA-EPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQS 679
              P +   + A  ++  G     +PATP  K  P                S   S SP+ 
Sbjct: 3669 VHPRKAVGSLAPGELARGTENGMKPATPKAKPGP----------------SSQGSGSPRP 3712

Query: 680  LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS-PSEIHKVGSSMRPLLQAQ 738
             + TG  S    +S             QL S   T P  PS PS       S  P    +
Sbjct: 3713 GTKTGGGSQPQPASG------------QLQSETATTPAKPSFPSR------SPAP----E 3750

Query: 739  GLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQD 798
             L    ++K  + G  E  +Q PH  S+ P+            E+ E S   +R++ Q  
Sbjct: 3751 RLPARAQAKSCTKGPREAGEQGPHG-SLGPK------------EKGESST--KRKKGQVP 3795

Query: 799  TAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLE 858
                S+  GS             G +P  P  P R          R+Q            
Sbjct: 3796 GPARSESVGSF------------GRAPSAPDKPPRTP--------RKQ------------ 3823

Query: 859  EDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALP 893
                AT  R L          +PRP PS++  A P
Sbjct: 3824 ----ATPSRVLPTKPKPNSQNKPRPPPSEQRKAEP 3854



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 52/219 (23%), Positives = 81/219 (36%), Gaps = 22/219 (10%)

Query: 3658 TGEEPGRRAA--KPHARD-LG-RHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASS 3713
            +G   G RA+  +P   D LG R   RP    + AP       P  P +A   + +R+S 
Sbjct: 967  SGSGGGGRASGLRPRRNDGLGERPPPRPRRPRTQAPGSRADPAPRVPRAAALPEETRSSR 1026

Query: 3714 AYHHASDSKKGSRQAHSGPAALQSKAE-PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAA 3772
                        R+A  G    +   +  Q + +L+    A   ++ + P     P G  
Sbjct: 1027 RRRLPPRKDPRKRKARGGAWGKELILKIVQQKNRLREYDFASESEEDEQPP----PRGPG 1082

Query: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQP---TTRGSAPAASQPAGKPQPGPSTAT 3829
             R       ++G G +  +  LTQ   + + Q      R  A     PA   +PG S   
Sbjct: 1083 FRG------RRGRGEKRKEVELTQGPREDEPQKPRKAARQEAGGDGAPANPEEPGGSR-- 1134

Query: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGP 3868
             P P   P+A   + S  T  A ++G  P+    P   P
Sbjct: 1135 -PGPGRSPQARGPSRSLETGAAAREG-GPKCADRPSVAP 1171



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 56/233 (24%), Positives = 79/233 (33%), Gaps = 47/233 (20%)

Query: 1433 EDLPQAPSGLA---AAGRAA---REKPLSASDGEGGTPQ---PSRAYSYFASS------- 1476
            ED PQ P   A   A G  A    E+P  +  G G +PQ   PSR+    A++       
Sbjct: 1104 EDEPQKPRKAARQEAGGDGAPANPEEPGGSRPGPGRSPQARGPSRSLETGAAAREGGPKC 1163

Query: 1477 --SPPLSPSSPSESPTFSPGKMGPRATAEF----------------------STQTPSPA 1512
               P ++P  P + PT +      R + +F                      + ++P  A
Sbjct: 1164 ADRPSVAPKDPLQVPTNTETSEETRPSLDFPQEAKEPETAEESAPDSTEFTEALRSPPAA 1223

Query: 1513 PASDMPRSPG--APTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTR 1570
             A +M  SPG   P   P     T TP    +        S   P +   L     +Q  
Sbjct: 1224 CAGEMGASPGLLIPEQPPPSRHDTGTPKPSGSLANTAPHGSSPTPGVGSLLGGPGGTQAP 1283

Query: 1571 MVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPG----PPGFPRVP 1619
            + H ++   P   P E        S T  P  S L  +       P GF R P
Sbjct: 1284 VSH-NSKDPPARQPGEFLAPVANPSSTACPKPSVLSSKISSFGCDPAGFNRDP 1335



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 26/110 (23%), Positives = 38/110 (34%), Gaps = 1/110 (0%)

Query: 3760 QSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAG 3819
            + P     P+     QP+      G   QPP +  T A    +      G A A   P  
Sbjct: 4    ERPRGAPPPTMTGDLQPRQVASSPGHPSQPPLEDNTPATRTTKGAREAGGQAQAMELPEA 63

Query: 3820 KPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPA 3869
            +P+        P          T G +G+ + P  GR+P   P+   G A
Sbjct: 64   QPRQARDGELKPPSLRGQAPSSTPGKRGSPQTP-PGRSPLQAPSRLAGRA 112



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 28/88 (31%), Positives = 33/88 (37%), Gaps = 12/88 (13%)

Query: 3808 RGSAPAASQPAGKP--QPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPG 3865
            R +  AA  P G P  Q G +    P     PRA  T  +   A  P    A     A  
Sbjct: 3215 RSAGKAAGSP-GDPWGQEGEAKKDSPGERAKPRARSTPSNPDGAATPDSASATALADAGS 3273

Query: 3866 PGPAGVKAGARPGGTPGAPAGQPGADGE 3893
            PGP        P  TP +P+  P A GE
Sbjct: 3274 PGP--------PRTTP-SPSPDPWAGGE 3292


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 98.2 bits (243), Expect = 1e-19
 Identities = 185/783 (23%), Positives = 264/783 (33%), Gaps = 118/783 (15%)

Query: 29  PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGN 88
           P P A + PSA  GG Q PA+ +  S+A P       GP     P + +    PK P G 
Sbjct: 220 PSPAARRRPSA-GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK-PKGL 277

Query: 89  QRAASPT---PKQASATTPGHESPRETRAQGPAGQEADG-PRRTLQVDSRTQRSGRSPSV 144
           Q    P    P++ +A   G  S        P+G +A   P               SP +
Sbjct: 278 QALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 145 SPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTP---SQPNFNTCTQC---HNKVC 198
           +      P SP + P +  LPS    P  +     +TP   + P+  T       H+   
Sbjct: 338 ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 199 NQCGFNPNP-HLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQP 257
                 P+P  L+ ++    L     +A    +T +PR ++Q  L SP+  PA +P   P
Sbjct: 398 PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPR-QTQASLTSPS-RPASTPPDSP 455

Query: 258 LGKPDQERSRGPGGPQPGSRQAETARATSVP---GPAQAAAPPEVGRVSPQPP-----QP 309
              P Q     P  P   +  +      S P    P QA +   +   SPQ P      P
Sbjct: 456 ---PLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALS--SLASHSPQAPLSSLIMP 510

Query: 310 TKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQP 369
              + +   PP+ + P  S T  P                L  L    L  AS  ++  P
Sbjct: 511 PLETQSSLAPPSLQTPPASLTTPPLE-------------NLPSLAPPPLQTASAPLTT-P 556

Query: 370 EADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGAL 429
             +T   PAP                   PL + P P   P  +T       P   P AL
Sbjct: 557 HLETPPCPAPC------------------PLQAPPSPLTTPPPETPSSIATPPPQAPPAL 598

Query: 430 --PKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTT 487
             P   G  SP          S  A  P   P   A+ PL QA  +  +  P +      
Sbjct: 599 ASPPLQGLPSPP--------LSPLATPPPQAPPXLALPPL-QAPPSPPASPPLSPLA--- 646

Query: 488 CRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRA 547
                       P+P           N     LL+     P   P      PP   P   
Sbjct: 647 -----------TPSPQAP--------NALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP 687

Query: 548 SGTSPLKQKGPQGLGQPS---GPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSS 604
           S T P   + P  L  P     P P  + P+S  A+P P    P A P     PS   S 
Sbjct: 688 SATPP--SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASP 745

Query: 605 VQEKKTRVPTKAEP-MPKPPPETTPTPATPKVKSGVRRAEP------ATPVVKAVPEAPK 657
                   P +  P +  PP +  P+P      S + +  P      ATP ++A+P  P 
Sbjct: 746 PMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPA 805

Query: 658 GGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGP- 716
               +     P+S  AS     L+     +  + ++      ++Q       S  +  P 
Sbjct: 806 SFPGQ----APFSPSASLPMSPLATPPPQAPPVLAAP-----LLQVPPSPPASPTLQAPR 856

Query: 717 HPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPE---AFDS 773
            PP+P     V      L  A G  P     P S+ +G +      S + TPE    +DS
Sbjct: 857 RPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDS 916

Query: 774 DEE 776
             E
Sbjct: 917 GPE 919



 Score = 92.8 bits (229), Expect = 6e-18
 Identities = 173/724 (23%), Positives = 254/724 (35%), Gaps = 134/724 (18%)

Query: 15  PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
           P PPG   P P P   P A +   A    G+ P A  A       +P   P  GP    G
Sbjct: 27  PRPPGS--PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84

Query: 75  STSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETRAQGPAGQE---------- 121
           ++SR    + P   +   +P  K  S    ++PG  S   T   GP GQ+          
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS--GTTRPGPLGQKGLRISAEETV 142

Query: 122 -----ADGPRRT-LQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKT 175
                 + P+R+ L   +R   SG +P       +  +         P P+ +  P   T
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202

Query: 176 SDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPR 235
                + S  + ++ T+            P+P               +R         P 
Sbjct: 203 EGPRKSVSSASEHSTTE------------PSP------------AARRRPSAGGGLQRPA 238

Query: 236 SKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGP-QPGSRQAETARATSVPGPAQAA 294
           S+S     +P  SPA S      G   +   R P  P QP  +  +  R   V  P + A
Sbjct: 239 SRSLSSSATPLSSPARS------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 295 APPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLG 354
           A P +G +S  P     PS  + RP     P  +AT +PA L  +      L   L    
Sbjct: 293 A-PALGPLSSSPLATPSPSGTKARPV--PPPDNAATPLPATLPPSPPLATPL--PLAPPS 347

Query: 355 ASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKT 414
            S      TL S  P A    Q  PS  TP +          P  L + P P   P + T
Sbjct: 348 PSAPPSLQTLPS--PPATPPSQAPPSMTTPPM--------QAPPSLQTIP-PIQVPHSLT 396

Query: 415 EPGARMGPGSGPGALPKTGGTT----------------SPKHGRAEHQAASKAAAKPKTM 458
            P  +  P   P AL     TT                SP+  +A   + S+ A+ P   
Sbjct: 397 SPSLQAPP--SPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDS 454

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQ----VCNLCGFNPTPHLVEKTEWLCLN 514
           P  +A   L  +     S SPA     +   +     + +L   +P   L          
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQAPL---------- 504

Query: 515 CQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP 574
                L+   L   + L PP+ Q PP      AS T+P  +  P  L  P  PL   ++P
Sbjct: 505 ---SSLIMPPLETQSSLAPPSLQTPP------ASLTTPPLENLP-SLAPP--PLQTASAP 552

Query: 575 LST---KASPLPSKASPQAKPL-RASEPSKTPSSVQEKKTRVP-------------TKAE 617
           L+T   +  P P+    QA P    + P +TPSS+     + P                 
Sbjct: 553 LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612

Query: 618 PMPKPPPETTPTPATPKVKS--GVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASR 675
           P+  PPP+  P  A P +++      + P +P+    P+AP    A  L+  P+S   S 
Sbjct: 613 PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP-NALAVHLLQAPFSPPPSP 671

Query: 676 SPQS 679
             Q+
Sbjct: 672 PVQA 675



 Score = 77.4 bits (189), Expect = 3e-13
 Identities = 173/712 (24%), Positives = 221/712 (31%), Gaps = 124/712 (17%)

Query: 30  GPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQ 89
           GP A   P APA   Q P     ++   P V  P     P  GP S+S    P  P G +
Sbjct: 256 GPSARGTPRAPAHPSQ-PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPS-PSGTK 313

Query: 90  RAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRG 149
               P P  A+   P    P    A  P       P     + +        PS +P   
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLAT-PLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSM 372

Query: 150 STPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHL 209
           +TP      P  AP    T+ PI     LTS   Q   +       +     G   +P L
Sbjct: 373 TTP------PMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG---SPTL 423

Query: 210 TQVKEWLCLNC-QMQRALGMDMTTA---------------PRSKSQQQLHSPALSPAHSP 253
                +L ++  Q Q +L      A               P S   Q   SPA+SP  SP
Sbjct: 424 QATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSP 483

Query: 254 AK-QPLGKPDQERSRGPGGP---------------QPGSRQAETARATS---------VP 288
               PL       S  P  P                P S Q   A  T+          P
Sbjct: 484 LTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAP 543

Query: 289 GPAQAAAPPEVGRVSPQPPQPTK-PSTAEPRP---PAGEAPAKSATAVPAGLGATEQTQ- 343
            P Q A+ P        PP P   P  A P P   P  E P+  AT  P    A      
Sbjct: 544 PPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPL 603

Query: 344 EGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGS- 402
           +GL        A+   QA   +++ P    Q  P+P    P       S +A P  L   
Sbjct: 604 QGLPSPPLSPLATPPPQAPPXLALPP---LQAPPSPPASPPLSPLATPSPQA-PNALAVH 659

Query: 403 ------GPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAA--K 454
                  P P P   A   P A   P   P A P +    S      +   +  A+    
Sbjct: 660 LLQAPFSPPPSPPVQAPFSPPA--SPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMS 717

Query: 455 PKTMPKERAICPLCQAELNVGSKSPAN--YNTCTTCRLQVCNLCGFNPTPHLVEKTEWLC 512
           P   P  +A  PL    L V    PA+   +   T   +V  L    P            
Sbjct: 718 PSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP------------ 765

Query: 513 LNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKA 572
                   L+     P  LP     +PP  AP  A  T PL     Q L  P    P +A
Sbjct: 766 --------LQVPPSPPASLPMSPLAKPPPQAPP-ALATPPL-----QALPSPPASFPGQA 811

Query: 573 S-------PLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAE-------- 617
                   P+S  A+P P      A PL    PS   S   +   R PT           
Sbjct: 812 PFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPR 871

Query: 618 ------PMPKPPPETTP--TPATPKVKSGVRRAEPATPVVKAVPEAPKGGEA 661
                 P P PPP  +P  T + P +      A      ++     P+GG A
Sbjct: 872 LTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAA 923



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 210/907 (23%), Positives = 291/907 (32%), Gaps = 142/907 (15%)

Query: 821  GGLSPLPPQPPARAAELTDEDFM-RRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGP 879
            G   P PP  PA    L     + R+ + E +         ++A         GT    P
Sbjct: 31   GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNP 90

Query: 880  RPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTL-QGGLR--------R 930
              RP  S      P  +   N + G    +   G A  T   G L Q GLR        R
Sbjct: 91   ASRPPASGRGERAPPAK---NTSPGP---VSSPGRASGTTRPGPLGQKGLRISAEETVAR 144

Query: 931  FKTIEL--NSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTP 988
             K  E    S  S G   D   GP P              G+     R       P++ P
Sbjct: 145  GKATEAPKRSALSAGARRDTS-GPTPGTPSPAMARRSRAAGTEVGLPR-----PAPSARP 198

Query: 989  SYTSGTSPTSLSSLEEDSDSSPS---RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEE 1045
               +     S+SS  E S + PS   RR+       QR A         P    +     
Sbjct: 199  RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 258

Query: 1046 LREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASP 1105
             R          + +    Q +R           ++   R+       P + SP+   SP
Sbjct: 259  ARGTPRAPAHPSQPKPKGLQALRPP---------QVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 1106 T-EELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSP 1164
            +  + R     +       +   PSP L +        PS           P+  +L SP
Sbjct: 310  SGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAP---------PSLQTLPSP 360

Query: 1165 TETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHG--GPSQPTGPR 1222
              TP  S   PS   P   A  + + +                 + PH    PS    P 
Sbjct: 361  PATPP-SQAPPSMTTPPMQAPPSLQTI--------------PPIQVPHSLTSPSLQAPPS 405

Query: 1223 GLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYE-EILQTSQSIVRMRQASSRDLAFA 1281
             L     Q TT         P  + T + L  +  + +   TS S        S  L   
Sbjct: 406  PLALSSLQATTS-----LGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAP 460

Query: 1282 EDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVR 1341
                       + S  + P+     PLT    P Q  + ++  +P +  SS   ++P + 
Sbjct: 461  LSLPASPPLQTSLSPAVSPLSS---PLT--IHPLQALSSLASHSPQAPLSS--LIMPPLE 513

Query: 1342 VTQHFAKETQDPLKLHSSPASPSSASKE----IGMPFSQGPGTPATTA---VAPCPAGLP 1394
                 A     P  L + PAS ++   E    +  P  Q    P TT      PCPA  P
Sbjct: 514  TQSSLA-----PPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCP 568

Query: 1395 RGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPL 1454
                 P SP  +    +PSS A     +P            PQAP  LA+        P 
Sbjct: 569  --LQAPPSPLTTPPPETPSSIA-----TPP-----------PQAPPALASPPLQGLPSP- 609

Query: 1455 SASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQ---TPSP 1511
              S      PQ     +     +PP  P+SP  SP  +P    P A A    Q   +P P
Sbjct: 610  PLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 669

Query: 1512 APASDMPRSPGAPTP-SPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTR 1570
            +P    P SP A  P SP     +Q P   + P L    S   +P M  +      +   
Sbjct: 670  SPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPP 729

Query: 1571 M------VHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPG---------PPGF 1615
            +      V  S   SP  SP+ T P         PP   Q+PP PP          PP  
Sbjct: 730  LAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPP--LQVPPSPPASLPMSPLAKPP-- 785

Query: 1616 PRVPSAGADGPLALYGWGALPAENIS------LCRISSVPGTSRVEPGPRTPGTAVVDLR 1669
            P+ P A A  PL      ALP+   S          +S+P +    P P+ P      L 
Sbjct: 786  PQAPPALATPPLQ-----ALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPL- 839

Query: 1670 TAVKPTP 1676
              V P+P
Sbjct: 840  LQVPPSP 846



 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 209/871 (23%), Positives = 291/871 (33%), Gaps = 129/871 (14%)

Query: 1164 PTETPSGSSTTPSSGRPL--KSAEEAYEEMMRKAELLQ--RQQGQAAGARGPHGGPSQPT 1219
            P  +P  +S T   G PL  K    + EE + + +  +  ++   +AGAR    GP+  T
Sbjct: 113  PVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 171

Query: 1220 GPRGLGSFEYQDTTDREYGQAA-----QPAAEGTPASLGAAVYEEILQTSQSIVRMRQAS 1274
                +        T+    + A     +P  EG   S+ +A      + S +  R R ++
Sbjct: 172  PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSA 230

Query: 1275 SRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGG 1334
               L     +   +   ++ +    P +   GP   GT      AP   S P        
Sbjct: 231  GGGL----QRPASRSLSSSATPLSSPARS--GPSARGTP----RAPAHPSQPKPKGLQAL 280

Query: 1335 RVIPDVRVTQHFAKETQDPLKLHSSP-ASPS-SASKEIGMPFSQGPGTPATTAVAPCP-- 1390
            R  P V   +  A     PL   SSP A+PS S +K   +P      TP    + P P  
Sbjct: 281  RP-PQVTPPRKDAAPALGPLS--SSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPL 337

Query: 1391 -AGLPRGYMTPASPAGSERSPSPSSTAHSYGHS-----PTTANYGSQTEDLPQAPSGLAA 1444
               LP    +P++P   +  PSP +T  S         P  A    QT    Q P  L +
Sbjct: 338  ATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTS 397

Query: 1445 AGRAAREKPLSASDGEG----GTPQPSRAYSYFASS-----SPPLSPSSPSESPTFSPGK 1495
                A   PL+ S  +     G+P     +S+   S     +   SPS P+ +P  SP  
Sbjct: 398  PSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPL 457

Query: 1496 MGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTP--RLVWQESSQE 1553
              P +         S +PA     SP   T  P+ A  +   H P  P   L+      +
Sbjct: 458  QAPLSLPASPPLQTSLSPAVSPLSSP--LTIHPLQALSSLASHSPQAPLSSLIMPPLETQ 515

Query: 1554 APFMVITLASD-ASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTP---PSVSQLPPEP 1609
            +     +L +  AS  T  +    S +P    T + P T  + +T P   P   Q PP P
Sbjct: 516  SSLAPPSLQTPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSP 575

Query: 1610 PGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTP-GTAVVDL 1668
               P  P  PS+ A  P       A P     L  + S P +    P P+ P   A+  L
Sbjct: 576  LTTPP-PETPSSIATPPPQAPPALASPP----LQGLPSPPLSPLATPPPQAPPXLALPPL 630

Query: 1669 RT-----AVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEH 1723
            +      A  P   + T       +LAV   +   +  P P  Q+    P    ++    
Sbjct: 631  QAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP--- 687

Query: 1724 TFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQT 1783
                +AT  S    S      Q  P     P  S          P   A   QV  +   
Sbjct: 688  ----SATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPA 743

Query: 1784 APYRSGPRGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHR 1843
            +P  S P   P          P +V PL     L        S+ + P   P P A P  
Sbjct: 744  SPPMS-PSATP----------PPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPAL 792

Query: 1844 ATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDM 1903
            ATP                                LP  PA      G  P S  A    
Sbjct: 793  ATPP----------------------------LQALPSPPA---SFPGQAPFSPSA---- 817

Query: 1904 VYKLPFGSSCTGTFHPAPSVPEKSMAD--AAPPGQSSSP-FYGPRDPEPPEPPTYRAQGV 1960
               LP     T    P P  P    A     PP   +SP    PR P  P P T     V
Sbjct: 818  --SLPMSPLAT----PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDT----SV 867

Query: 1961 VGPGPHEEQRPYPQGLPGRLYSS-MSDTNLA 1990
             GP       P P   P R  SS +S  +LA
Sbjct: 868  SGPRLTLALAPGPPPPPSRSPSSTLSGPDLA 898



 Score = 59.3 bits (142), Expect = 7e-08
 Identities = 109/433 (25%), Positives = 146/433 (33%), Gaps = 52/433 (12%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGG--GQLPAAGAARSTAVPPVPGPGP--GPGPG 70
            P  P  + P   P   P +  PP +P+     Q P + AA    VPP P   P   P   
Sbjct: 664  PFSPPPSPPVQAPFSPPAS--PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721

Query: 71   PGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQ 130
            P P +      P   +     ASP P   SAT P    P       P  Q    P  +L 
Sbjct: 722  PPPQAPPPLAAPPLQVPPSPPASP-PMSPSATPPPRVPPL---LAAPPLQVPPSPPASLP 777

Query: 131  VDSRTQRSGRSPSV--SPDRGSTPTSPYSVPQIAPL-PSSTL-----------CPICKTS 176
            +    +   ++P    +P   + P+ P S P  AP  PS++L            P    +
Sbjct: 778  MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 177  DLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRS 236
             L   P  P  +   Q   +        P P  +     L L      AL       P  
Sbjct: 838  PLLQVPPSPPASPTLQAPRRPPT-----PGPDTSVSGPRLTL------ALAPGPPPPPSR 886

Query: 237  KSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGP-AQAAA 295
                 L  P L+  HS +     +  +    GP G    S   +   A   P   ++  A
Sbjct: 887  SPSSTLSGPDLA-GHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPA 945

Query: 296  PPEVGRVSPQPPQPTKPSTAEPRPPAG-------EAPAKSATAVPAGL--GATEQTQEGL 346
            PP   R +P  P P  P+T  P    G       E P +SAT  P  L  G +  T  G 
Sbjct: 946  PPLAFRGAPGAPLPWPPATG-PGSADGLCTIYETEGP-ESATPAPGALDPGPSPGTSGGK 1003

Query: 347  TGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGP 406
                 G GAS  +     +   P    Q        +  ++   A   AG    GSG GP
Sbjct: 1004 AAAGAGAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAG----GSGGGP 1059

Query: 407  GPAPGAKTEPGAR 419
            G A G     GAR
Sbjct: 1060 GGAEGGGVTGGAR 1072



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 70/275 (25%), Positives = 100/275 (36%), Gaps = 42/275 (15%)

Query: 3635 GPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKK 3694
            GP R A             SGR     P +  +       GR        P         
Sbjct: 78   GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL-------- 129

Query: 3695 GQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPA--------ALQSKAE------ 3740
            GQ G   SAE +     ++     S    G+R+  SGP         A +S+A       
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQI---PSGAASRQPQTQQQQQGLGLQPP-----QQ 3792
            P+  P  + R    GP++S S +S      PS AA R+P       G GLQ P       
Sbjct: 190  PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-----GGGLQRPASRSLSS 244

Query: 3793 ALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAP 3852
            + T      +S P+ RG+  A + P+ +P+P    A  P    PPR +        + +P
Sbjct: 245  SATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSP 303

Query: 3853 QQGRAP---QAQPAPGPGPAGVKAGARPGGTPGAP 3884
                +P   +A+P P P  A   A   P   P +P
Sbjct: 304  LATPSPSGTKARPVPPPDNA---ATPLPATLPPSP 335



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 103/449 (22%), Positives = 158/449 (35%), Gaps = 58/449 (12%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSG--GRVIPDVRVTQHFAKETQDPLKLHSSPAS-- 1362
            P+TP       AA      P +  + G  G  IP+   +   A  T+       +PAS  
Sbjct: 38   PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPE---SAPRAGPTRSAGTSSRNPASRP 94

Query: 1363 PSSASKEIGMPF---SQGPGTP---ATTAVAPCPAGLPRGYMTPASP--AGSERSPSPSS 1414
            P+S   E   P    S GP +    A+    P P G  +G    A    A  + + +P  
Sbjct: 95   PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG-QKGLRISAEETVARGKATEAPKR 153

Query: 1415 TAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFA 1474
            +A S G    T+     T     A    AA       +P  ++     T  P ++ S  +
Sbjct: 154  SALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSAS 213

Query: 1475 SSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGT 1534
              S      +    P+   G   P + +  S+ TP  +PA   P + G P          
Sbjct: 214  EHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTP---------- 263

Query: 1535 QTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGY 1594
            + P  PS P+    ++ +  P  V     DA+     + +S   +P  S T+ +P     
Sbjct: 264  RAPAHPSQPKPKGLQALR--PPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321

Query: 1595 SQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGT--S 1652
            +  TP   + LPP PP     P  P +              P+   SL  + S P T  S
Sbjct: 322  NAATPLPAT-LPPSPPLATPLPLAPPS--------------PSAPPSLQTLPSPPATPPS 366

Query: 1653 RVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQ 1712
            +  P   TP          + P  +        LTS +++A    LAL  +    S    
Sbjct: 367  QAPPSMTTPPMQAPPSLQTIPPIQV-----PHSLTSPSLQAPPSPLALSSLQATTSLGSP 421

Query: 1713 PLVINLNAQEHTFLATA---TTVSITMAS 1738
             L        H+FL  +   T  S+T  S
Sbjct: 422  TL-----QATHSFLTMSPRQTQASLTSPS 445



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 184/783 (23%), Positives = 262/783 (33%), Gaps = 117/783 (14%)

Query: 2483 APGRGPPLAAAELAQN----------GQYWPPLTHAAFIAMAGP---EGLGQPREPVLHR 2529
            AP  GP  +A   ++N          G+  PP  + +   ++ P    G  +P  P+  +
Sbjct: 74   APRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG-PLGQK 132

Query: 2530 GLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGT-EPCVVRRIADSSVQTD 2588
            GL  SA +    T  + +A+ +  +   S    RD      GT  P + RR    S    
Sbjct: 133  GLRISAEE----TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARR----SRAAG 184

Query: 2589 DEDGESRYLLSRRRRARRSADC-SVQTDDEDSAEWEQPVRRRRSRLPRHSDSGSDSKHDA 2647
             E G  R   S R R        SV +  E S     P  RRR        +G   +  A
Sbjct: 185  TEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRP------SAGGGLQRPA 238

Query: 2648 TASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAP 2707
            + S SS+A  + + +  G            P Q P+      + A   P+V   R  +AP
Sbjct: 239  SRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ-PKPKG---LQALRPPQVTPPRKDAAP 294

Query: 2708 EKTGRGESLACQTEPDG-QAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPL 2766
                   S      P G +A+ V  P        +   P   + TP PL       P  L
Sbjct: 295  ALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSL 354

Query: 2767 E-IGYQAHLPPESLSQLVSRQPPKSP---------QV--------LYSPVSPLSPHRLLD 2808
            + +      PP      ++  P ++P         QV        L +P SPL+   L  
Sbjct: 355  QTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQA 414

Query: 2809 TSFASSERLNKAH----VSP-QKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEES 2863
            T+   S  L   H    +SP Q   +  S  R  + P     LQ  LS   P SP  + S
Sbjct: 415  TTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQAPLS--LPASPPLQTS 472

Query: 2864 AKERFSLYQHQGGLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLL 2923
                 S       L S ++  P  +L      +  +P       PL  Q+S    +    
Sbjct: 473  LSPAVS------PLSSPLTIHPLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTP 526

Query: 2924 QRGLTGPT--TVPATKASLLRELDRDLRLVEHESTK------LRKKQAELDEEEKEIDAK 2975
               LT P    +P+     L+     L     E+        L+   + L     E  + 
Sbjct: 527  PASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSS 586

Query: 2976 LKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDF 3035
            +        Q   +LA        PPL+GL                L    TP  Q    
Sbjct: 587  IATPP---PQAPPALAS-------PPLQGLPSPP------------LSPLATPPPQAPPX 624

Query: 3036 PATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAH--QAPTYPGPSTYPAPA 3093
             A     A PS P +        P+PQ          N    H  QAP  P PS      
Sbjct: 625  LALPPLQAPPSPPASPPLSPLATPSPQ--------APNALAVHLLQAPFSPPPSPPVQAP 676

Query: 3094 FPPGASYPAEP-GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLAD 3152
            F P AS P  P   P  QA  P    A    +P +     P+   +  P Q P   +   
Sbjct: 677  FSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 734

Query: 3153 LEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAP 3212
            L+  VP +    ASP  PMS + +      P +++   Q  VP  P A    S    P P
Sbjct: 735  LQ--VPPSPP--ASP--PMSPSATPPPRVPPLLAAPPLQ--VPPSPPASLPMSPLAKPPP 786

Query: 3213 TYP 3215
              P
Sbjct: 787  QAP 789



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 56/214 (26%), Positives = 79/214 (36%), Gaps = 21/214 (9%)

Query: 2157 GHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVL 2216
            G PSP  +A+   AAG    + +  PS       +G   S  +    +T      PA+  
Sbjct: 170  GTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE--PSPAARR 226

Query: 2217 RPMVRGGMYRPYA-SGGITAVPLTSLTRVPMIA---PRVPLGPT-----GLYRYPAPSRF 2267
            RP   GG+ RP + S   +A PL+S  R    A   PR P  P+     GL     P   
Sbjct: 227  RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 286

Query: 2268 PIASSVPPAEGPVYLG-----KPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEA 2322
            P      PA GP+         P+  KA     P     P+ A      P  TP  +   
Sbjct: 287  PPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPP 346

Query: 2323 AGAPAPA----PLAGQKPPADAAPGGGSGALSRP 2352
            + +  P+    P     PP+ A P   +  +  P
Sbjct: 347  SPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAP 380



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 57/242 (23%), Positives = 84/242 (34%), Gaps = 36/242 (14%)

Query: 3636 PGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHE----ARPHSQPSSAPAM 3691
            PG  + A   R     R +G   G      +A+P     G  +    A  HS    +PA 
Sbjct: 169  PGTPSPAMARR----SRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224

Query: 3692 PKKGQPG----YPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPA-----ALQSKAEPQ 3742
             ++   G     P+S   S  +   S+   +  S +G+ +A + P+      LQ+   PQ
Sbjct: 225  RRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ 284

Query: 3743 AQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQ 3802
              P  +    A GP  S SP +   PSG  +R            + PP  A T       
Sbjct: 285  VTPPRKDAAPALGPLSS-SPLATPSPSGTKARP-----------VPPPDNAATPL----- 327

Query: 3803 SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQP 3862
              P T   +P  + P     P PS     Q    P A   + +  +   P     P  Q 
Sbjct: 328  --PATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQT 385

Query: 3863 AP 3864
             P
Sbjct: 386  IP 387



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 68/260 (26%), Positives = 93/260 (35%), Gaps = 30/260 (11%)

Query: 2107 SMDQYGGRHGSGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQ 2166
            S  + G    +G    +     P  G G  AP +     PG + +P    G   PG L Q
Sbjct: 73   SAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK-NTSPGPVSSPGRASGTTRPGPLGQ 131

Query: 2167 YGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG---G 2223
             G        V +   + A  R+A   + +      +   P T  PA   R    G   G
Sbjct: 132  KGLRISAEETVARGKATEAPKRSA---LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVG 188

Query: 2224 MYRPYASG-----------GITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASS 2272
            + RP  S             +++    S T     A R P    GL R   P+   ++SS
Sbjct: 189  LPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR---PASRSLSSS 245

Query: 2273 VPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLA 2332
              P   P   G  A         PS+P+ P G     P   T P   K+A  APA  PL+
Sbjct: 246  ATPLSSPARSGPSARGTPRAPAHPSQPK-PKGLQALRPPQVTPPR--KDA--APALGPLS 300

Query: 2333 GQKPPADAAPGGGSGALSRP 2352
               P A  +P   SG  +RP
Sbjct: 301  -SSPLATPSP---SGTKARP 316



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 41/130 (31%), Positives = 54/130 (41%), Gaps = 15/130 (11%)

Query: 3769 SGAASRQPQTQQQQQGL------GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQ 3822
            +GAA+R P  +    GL      G   P   +T A L+        G  P A +  G   
Sbjct: 10   AGAAARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-- 65

Query: 3823 PGPSTATGPQP-AGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT- 3880
             G +T     P AGP R+  T+     ++ P  GR  +A PA    P  V +  R  GT 
Sbjct: 66   -GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 3881 -PGAPAGQPG 3889
             PG P GQ G
Sbjct: 125  RPG-PLGQKG 133



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 9/122 (7%)

Query: 2235 AVPLTSLTRVP-MIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGA 2293
            A   T   R P ++ PR P  P      P P   P A  V  A G V   KP A +A G 
Sbjct: 12   AAARTPAARAPGLLTPRPPGSPR-----PPPPVTPAALRVLGAAGAVGR-KPLAERAGGI 65

Query: 2294 GGPSRPEMP--VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSR 2351
            GG + PE     G  R     +  PA+   A+G    AP A    P   +  G +   +R
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 2352 PG 2353
            PG
Sbjct: 126  PG 127



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 26/221 (11%)

Query: 2136 SAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIY 2195
            S P S  P  P L    + P   P   +L+   PA          L S  T+     +  
Sbjct: 445  SRPASTPPDSPPLQAPLSLPASPPLQTSLS---PAVSP-------LSSPLTIHPLQALSS 494

Query: 2196 STINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRV---PMIAPRVP 2252
               ++P A    +   P      +    +  P AS  +T  PL +L  +   P+     P
Sbjct: 495  LASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPAS--LTTPPLENLPSLAPPPLQTASAP 552

Query: 2253 LGPTGLYRYPAPSRFPIAS-----SVPPAEGPVYLGKP------AAAKAPGAGGPSRPEM 2301
            L    L   P P+  P+ +     + PP E P  +  P      A A  P  G PS P  
Sbjct: 553  LTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLS 612

Query: 2302 PVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            P+     +  P      ++     PA  PL+    P+  AP
Sbjct: 613  PLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAP 653



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 77/295 (26%), Positives = 103/295 (34%), Gaps = 38/295 (12%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPA-PAFPPGAS 3099
            AP +P      Q P F PPA    + S  P     P+  AP    P + PA P   P A+
Sbjct: 663  APFSPPPSPPVQAP-FSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSAT 721

Query: 3100 YP--AEPGL--------PNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTS 3149
             P  A P L        P+  A  P    A  TP P     L   P   + P   P    
Sbjct: 722  PPPQAPPPLAAPPLQVPPSPPASPPMSPSA--TPPPRVPPLLAAPPL--QVPPSPPASLP 777

Query: 3150 LADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQS 3209
            ++ L +  P     +A+P  P+ + PS      P  S     G+ P  P A    S   +
Sbjct: 778  MSPLAKPPPQAPPALATP--PLQALPS------PPASF---PGQAPFSPSASLPMSPLAT 826

Query: 3210 PAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEP-----LGPGSSGR 3264
            P P  P       L+  VP +      +    +  T   PD+    P     L PG    
Sbjct: 827  PPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPT-PGPDTSVSGPRLTLALAPGPPPP 883

Query: 3265 PGKEPGEPGVLDGPTLPCCYARGEEESEE-DSYDPRGKGGHLRSMESNGRPASTH 3318
            P + P     L GP L    +      EE   YD   +GG   S   +   A+ H
Sbjct: 884  PSRSPS--STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 936



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 53/190 (27%), Positives = 67/190 (35%), Gaps = 26/190 (13%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQ--PSRASSAYHHASDSKKGSRQAHSGPAALQSK 3738
            P S P  AP  P    P  PS+   SQ  PS A      A   +       S P +  + 
Sbjct: 668  PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA------APPLQVPPSPPASPPMSPSAT 721

Query: 3739 AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQAR 3798
              PQA P L    AAP  Q   SP +    S +A+  P+         LQ P        
Sbjct: 722  PPPQAPPPL----AAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPP------- 770

Query: 3799 LQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAP 3858
                S P +   +P A  P   PQ  P+ AT P  A P       G    + +     +P
Sbjct: 771  ----SPPASLPMSPLAKPP---PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823

Query: 3859 QAQPAPGPGP 3868
             A P P   P
Sbjct: 824  LATPPPQAPP 833



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 76/259 (29%), Positives = 94/259 (36%), Gaps = 42/259 (16%)

Query: 1300 PMKQNGGPLTPGTSPTQLAAP---VSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKL 1356
            PM  +  P  P  +P  LAAP   V  S P S   S     P  RV    A     PL++
Sbjct: 715  PMSPSATP--PPQAPPPLAAPPLQVPPSPPASPPMSPSAT-PPPRVPPLLAAP---PLQV 768

Query: 1357 HSSPASPSSASKEIGMPFSQGP---GTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPS 1413
              SP + S     +  P  Q P    TP   A+   PA  P     P SP+ S    SP 
Sbjct: 769  PPSPPA-SLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG--QAPFSPSAS-LPMSPL 824

Query: 1414 STAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGE--------GGTPQ 1465
            +T       P  A    Q    P A   L A  R     P ++  G         G  P 
Sbjct: 825  ATPPPQA-PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 883

Query: 1466 PSRAYSYFASSSPPLS------PSSPSESPTFSPGKMG-----PRATAEFSTQTPS---- 1510
            PSR+ S    S P L+       S+P E   +  G  G     P   AE +   P+    
Sbjct: 884  PSRSPSS-TLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSR 942

Query: 1511 -PAPASDMPRSPGAPTPSP 1528
             PAP      +PGAP P P
Sbjct: 943  GPAPPLAFRGAPGAPLPWP 961



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 53/236 (22%), Positives = 79/236 (33%), Gaps = 19/236 (8%)

Query: 526 GEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK 585
           G P P PP T     V     A G  PL ++   G+G     +P  A       S   S 
Sbjct: 31  GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG-GIG--GATIPESAPRAGPTRSAGTSS 87

Query: 586 ASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
            +P ++P  +    + P +         T   P+  P   +  T   P  + G+R +   
Sbjct: 88  RNPASRPPASGRGERAPPAKN-------TSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 646 TPVVKAVPEAPK-----GGEAEDLVGK----PYSQDASRSPQSLSDTGYSSDGISSSQSE 696
           T       EAPK      G   D  G     P    A RS  + ++ G      S+    
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 697 ITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSG 752
            T   ++ V        T P P +       G   RP  ++   + +  S P  SG
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 97/410 (23%), Positives = 128/410 (31%), Gaps = 87/410 (21%)

Query: 3446 PSAYSGEKLSSHDFSGWGKGYEREREAV----ERLQKAGPKPSSLSMAHSRVRPPMRSQA 3501
            P    G ++S+ +    GK  E  + +      R   +GP P + S A +R     RS+A
Sbjct: 128  PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-----RSRA 182

Query: 3502 SEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYIL 3561
            +  E     L RP P+  P PP                      +GPR       E    
Sbjct: 183  AGTEVG---LPRPAPSARPRPP---------------------TEGPRKSVSSASE---- 214

Query: 3562 DDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYD 3621
               H     S A            +P                SS++    PAR       
Sbjct: 215  ---HSTTEPSPAARRRPSAGGGLQRPASRSLS----------SSATPLSSPARSG----- 256

Query: 3622 EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARP 3681
                    P   G P   A A   +    G  + R     P R+ A P    LG   + P
Sbjct: 257  --------PSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA---LGPLSSSP 303

Query: 3682 HSQPSSAPAM------PKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQA-HSGPAA 3734
             + PS +         P       P++   S P          S S   S Q   S PA 
Sbjct: 304  LATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPAT 363

Query: 3735 LQSKAEP-------QAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGL 3787
              S+A P       QA P LQ       P    SPS +  PS  A    Q         L
Sbjct: 364  PPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTL 423

Query: 3788 QPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
            Q     LT +  Q Q+   T  S PA++ P   P   P +     PA PP
Sbjct: 424  QATHSFLTMSPRQTQAS-LTSPSRPASTPPDSPPLQAPLSL----PASPP 468



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 114/516 (22%), Positives = 152/516 (29%), Gaps = 144/516 (27%)

Query: 1829 LKPGPVPEPGAEPHRATPAELRSHALPGA--RKPHTVVVQMGEGTAGTVTTLLPEEPAGA 1886
            L P P   P   P   TPA LR     GA  RKP      + E   G     +PE    A
Sbjct: 25   LTPRPPGSPRPPPP-VTPAALRVLGAAGAVGRKP------LAERAGGIGGATIPESAPRA 77

Query: 1887 LDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRD 1946
                                 P  S+ T + +PA   P     + APP +++SP      
Sbjct: 78   G--------------------PTRSAGTSSRNPASRPPASGRGERAPPAKNTSP------ 111

Query: 1947 PEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRI---GQ 2003
               P     RA G   PGP                       L + GL   A+     G+
Sbjct: 112  --GPVSSPGRASGTTRPGP-----------------------LGQKGLRISAEETVARGK 146

Query: 2004 LFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSS 2063
              + P R +                        L  G+  D   PT     P   RR  +
Sbjct: 147  ATEAPKRSA------------------------LSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 2064 VSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGGGGPD 2123
                    R  P        E      S+ +    +    A         R  S GGG  
Sbjct: 183  AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGG-- 233

Query: 2124 LVQYQPQHGPGLSAPQSLVPLR--PGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLL 2181
             +Q         SA     P R  P   G P  P  HPS     Q  P   Q     Q+ 
Sbjct: 234  -LQRPASRSLSSSATPLSSPARSGPSARGTPRAP-AHPS-----QPKPKGLQALRPPQVT 286

Query: 2182 PSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSL 2241
            P       A G + S+   P+A   P  T+   V           P      T +P T  
Sbjct: 287  PPRKDAAPALGPLSSS---PLATPSPSGTKARPV-----------PPPDNAATPLPATLP 332

Query: 2242 TRVPM-----IAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP 2296
               P+     +AP  P  P  L   P+P       + PP++ P     P+    P    P
Sbjct: 333  PSPPLATPLPLAPPSPSAPPSLQTLPSP------PATPPSQAP-----PSMTTPPMQAPP 381

Query: 2297 SRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLA 2332
            S   +P         P   P ++   +    P+PLA
Sbjct: 382  SLQTIP---------PIQVPHSLTSPSLQAPPSPLA 408



 Score = 38.9 bits (89), Expect = 0.10
 Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 18/208 (8%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
            P   P  AP  P    P    S+  + P +A  A   AS   +G     S P +  +   
Sbjct: 564  PAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPAL--ASPPLQG---LPSPPLSPLATPP 618

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
            PQA P L    A P  Q   SP +    S  A+  PQ         LQ P          
Sbjct: 619  PQAPPXL----ALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP------- 667

Query: 3801 QQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQA 3860
              S P     +P AS P   P   P +   P  A PP     +       +P     PQA
Sbjct: 668  PPSPPVQAPFSPPASPPVS-PSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQA 726

Query: 3861 QPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
             P     P  V   + P   P +P+  P
Sbjct: 727  PPPLAAPPLQVPP-SPPASPPMSPSATP 753



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 42/169 (24%), Positives = 60/169 (35%), Gaps = 12/169 (7%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQP---PAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAP 3092
            P   AAP     P+    P   P   P P+       P     P+  A     P   P P
Sbjct: 727  PPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPP 786

Query: 3093 AFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLAD 3152
              PP  + P    LP+     P   + GQ P   + S   P+   +  P Q P   +   
Sbjct: 787  QAPPALATPPLQALPS-----PPASFPGQAPF--SPSASLPMSPLATPPPQAPPVLAAPL 839

Query: 3153 LE-QKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRA 3200
            L+    P     + +P  P +  P +TS SGP ++     G  P   R+
Sbjct: 840  LQVPPSPPASPTLQAPRRPPTPGP-DTSVSGPRLTLALAPGPPPPPSRS 887



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 73/260 (28%), Positives = 85/260 (32%), Gaps = 63/260 (24%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRA---------SSAYHHASDSKKGSRQAHSG 3731
            P S P+S P  P    P     A  + P +A           A    S S   S  A   
Sbjct: 769  PPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 828

Query: 3732 PAA--------LQSKAEPQAQPQLQG--RQAAPGPQQSQS--------------PSSRQI 3767
            P A        LQ    P A P LQ   R   PGP  S S              P SR  
Sbjct: 829  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888

Query: 3768 PS--------GAASRQPQTQQQ--------QQGLGLQPPQQALTQARLQQQSQPTTRGSA 3811
             S        G +S    T ++        + G    PP  A   A         +RG A
Sbjct: 889  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAAC---HPAAWSRGPA 945

Query: 3812 P--AASQPAGKPQPGPSTATGPQPA-GPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGP 3868
            P  A     G P P P  ATGP  A G     +T G +    AP         P P PG 
Sbjct: 946  PPLAFRGAPGAPLPWPP-ATGPGSADGLCTIYETEGPESATPAPGA-----LDPGPSPGT 999

Query: 3869 AGVKAGARPGGTPGAPAGQP 3888
            +G KA A  G   GA +  P
Sbjct: 1000 SGGKAAA--GAGAGASSRSP 1017



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 48/182 (26%), Positives = 63/182 (34%), Gaps = 10/182 (5%)

Query: 12  GDGPLPPGGAGP-GPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG 70
           G  P  P  + P  P   P P A  PP   A   Q+P +  A  T   P   P PGP   
Sbjct: 809 GQAPFSPSASLPMSPLATPPPQA--PPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTS 866

Query: 71  PGPGSTSRRLDPKEPLGNQRAASPT---PKQASATTPGHESPRETRA--QGPAGQEADGP 125
                 +  L P  P    R+ S T   P  A  ++    +P E R    GP G  A  P
Sbjct: 867 VSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASP 926

Query: 126 RRTLQVDS-RTQRSGRSPSVSPDRGSTPTSPYS-VPQIAPLPSSTLCPICKTSDLTSTPS 183
               ++ +       R P+        P +P    P   P  +  LC I +T    S   
Sbjct: 927 PPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATP 986

Query: 184 QP 185
            P
Sbjct: 987 AP 988



 Score = 35.8 bits (81), Expect = 0.86
 Identities = 38/146 (26%), Positives = 48/146 (32%), Gaps = 11/146 (7%)

Query: 2207 PITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSR 2266
            P+T  P   L  +     + P A       PL+SL  +P +  +  L P  L   PA   
Sbjct: 483  PLTIHPLQALSSLAS---HSPQA-------PLSSLI-MPPLETQSSLAPPSLQTPPASLT 531

Query: 2267 FPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAP 2326
             P   ++P    P      A    P    P  P      A   PL T  P      A  P
Sbjct: 532  TPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPP 591

Query: 2327 APAPLAGQKPPADAAPGGGSGALSRP 2352
              AP A   PP    P      L+ P
Sbjct: 592  PQAPPALASPPLQGLPSPPLSPLATP 617



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 81/367 (22%), Positives = 122/367 (33%), Gaps = 76/367 (20%)

Query: 1499 RATAEFSTQTPSP-APASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFM 1557
            +A A  + +TP+  AP    PR PG+P P P           P TP          A   
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPP-----------PVTP----------AALR 45

Query: 1558 VITLASDASSQTRMVHASA-------STSPLCSPTETQPTTHGYSQTTPPSV---SQLPP 1607
            V+  A     +     A          ++P   PT +  T+     + PP+     + PP
Sbjct: 46   VLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP 105

Query: 1608 ---EPPGPPGFP-RVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGT 1663
                 PGP   P R       GPL   G      E ++  + +  P  S +  G R    
Sbjct: 106  AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR---- 161

Query: 1664 AVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALD-PIPGRQSTAVQPLVINLNAQE 1722
                 R    PTP      G    ++A  +R  G  +  P P   +    P         
Sbjct: 162  -----RDTSGPTP------GTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205

Query: 1723 HTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQ 1782
               +++A+  S T  S    A +++P               GGG     ++         
Sbjct: 206  RKSVSSASEHSTTEPSP---AARRRP-------------SAGGGLQRPASRSLSSSATPL 249

Query: 1783 TAPYRSGP--RGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIG-LKPGPVPEPGA 1839
            ++P RSGP  RG PR         P  +  L    V   +   A ++G L   P+  P  
Sbjct: 250  SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 1840 EPHRATP 1846
               +A P
Sbjct: 310  SGTKARP 316



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 55/231 (23%), Positives = 72/231 (31%), Gaps = 34/231 (14%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASS--------------AYHHASDSKKGSR 3726
            P   P +  + P +G P  P S   + P +A                A    S     S 
Sbjct: 591  PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650

Query: 3727 QAHSGPAA--LQSKAEPQAQPQLQGR---QAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ 3781
            QA +  A   LQ+   P   P +Q      A+P    S +P S+  PS AA         
Sbjct: 651  QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP------- 703

Query: 3782 QQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAG-KPQPGPSTATGPQPAGPPRAE 3840
                 LQ P        +   + P  +   P A+ P    P P  S    P    PPR  
Sbjct: 704  -----LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVP 758

Query: 3841 QTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARP--GGTPGAPAGQPG 3889
                +      P    +    P   P P    A A P     P  PA  PG
Sbjct: 759  PLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPG 809



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 68/255 (26%), Positives = 88/255 (34%), Gaps = 40/255 (15%)

Query: 2129 PQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPG-NLAQYGP----AAGQGTAVRQLLPS 2183
            PQ  P L+AP   VP  P        P   P+PG + +  GP    A   G         
Sbjct: 829  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 888

Query: 2184 TATVRAAD--GMIYSTINTP-------------IAATLPITTQPASVLRPMVRGGMYRPY 2228
            ++T+   D  G   S  +TP              AA+ P   + A+        G   P 
Sbjct: 889  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 948

Query: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAP-SRFPIASSVPPAEGPVYLGKPAA 2287
            A  G    P   L   P   P    G   +Y    P S  P   ++ P   P   G  AA
Sbjct: 949  AFRGAPGAP---LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 1005

Query: 2288 AKAPGAGGPSRP-------EMPVGAAREEPLP-----TTTPAAIKEAAGAPAPAPLAGQK 2335
            A A GAG  SR        E+P+GA +   +      T   AA + AAG     P   + 
Sbjct: 1006 AGA-GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE- 1063

Query: 2336 PPADAAPGGGSGALS 2350
                   GG   ALS
Sbjct: 1064 --GGGVTGGARAALS 1076



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 51/214 (23%), Positives = 63/214 (29%), Gaps = 30/214 (14%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
            P S P  AP       P   S +    P  +    H        S  +HS  A L S   
Sbjct: 452  PDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQ--ALSSLASHSPQAPLSSLIM 509

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
            P  + Q            S +P S Q P  + +  P   +    L   P Q A       
Sbjct: 510  PPLETQ-----------SSLAPPSLQTPPASLTTPPL--ENLPSLAPPPLQTASAPLTTP 556

Query: 3801 QQSQPTTRGSAPAASQPAGKPQPGPSTATG---PQPAGPPRAEQTNGSKGTAKAPQQG-R 3856
                P      P  + P+    P P T +    P P  PP           A  P QG  
Sbjct: 557  HLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPP---------ALASPPLQGLP 607

Query: 3857 APQAQPAPGPGPAGVKAGARP--GGTPGAPAGQP 3888
            +P   P   P P      A P     P  PA  P
Sbjct: 608  SPPLSPLATPPPQAPPXLALPPLQAPPSPPASPP 641



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 13/88 (14%)

Query: 3812 PAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV 3871
            PAA  P G   P P  +  P P   P A +  G+ G       GR P A+ A G G A +
Sbjct: 17   PAARAP-GLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-----GRKPLAERAGGIGGATI 70

Query: 3872 KAGA-RPGGTPGA------PAGQPGADG 3892
               A R G T  A      PA +P A G
Sbjct: 71   PESAPRAGPTRSAGTSSRNPASRPPASG 98


>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
          Length = 5478

 Score = 96.7 bits (239), Expect = 4e-19
 Identities = 379/1764 (21%), Positives = 571/1764 (32%), Gaps = 296/1764 (16%)

Query: 71   PGPGSTSRRLDPKEPLG---NQRAASPTPKQASAT-TPGHESPRETRAQGPAGQEADGPR 126
            PGP  T    D     G      A+   P     T +PG  +P     +      + G  
Sbjct: 315  PGPTHTIAFPDSTTMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTTFHSSPGYT 374

Query: 127  RTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPN 186
            +T ++   T  SG   + +P   ST +     P     PSS+     + +   S PS  +
Sbjct: 375  KTTRLPDNTTTSGLLEASTPVHSSTGS-----PHTTLSPSSSTTHEGEPTTFQSWPSSKD 429

Query: 187  FNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPA 246
             +                P P  T    ++ L+     +     TT   + S    HS  
Sbjct: 430  TS----------------PAPSGT-TSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSEE 472

Query: 247  LSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQP 306
             +P HS        P   RS   G  +      E+      PG  Q    PE    S   
Sbjct: 473  STPVHSSPVATATTPPPARSATSGHVE------ESTAYHRSPGSTQTMHFPESSTTSGHS 526

Query: 307  PQPTK--PSTAEPRPPAGEAPAKSA-TAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST 363
             +      ST   +       A  A T+  + LG+TE T    +  + G      ++ S 
Sbjct: 527  EESATFHGSTTHTKSSTPSTTAALAHTSYHSSLGSTETTHFRDSSTISGR-----SEESK 581

Query: 364  LMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPA-PGAKTEPGAR--- 419
                 P+A       P+  TP ++  D++    P P+ SG     A PG+ T+PG     
Sbjct: 582  ASHSSPDAMAT-TVLPAGSTPSVLVGDST----PSPISSGSMETTALPGSTTKPGLSEKS 636

Query: 420  ----MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG 475
                  P S P         TS         + S+  +   T        P    E    
Sbjct: 637  TTFYSSPRS-PDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTAS 695

Query: 476  SKSPANYNTCTTCRLQVCNLCG-----FNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP 530
              SP   +T  +      +  G     F+  P   E T  L  N     LLE S+   + 
Sbjct: 696  HSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETT-LLPDNTTASGLLEASMPVHSS 754

Query: 531  LPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKAS--- 587
               P +   P G+  R   ++            PS      A P +T A   PS  S   
Sbjct: 755  TRSPHTTLSPAGSTTRQGESTTFHS-------WPSSKDTRPAPPTTTSAFVEPSTTSHGS 807

Query: 588  PQAKPLRASEPSKTPSSVQEKKTRV---PTKAEPMPKPPPETTP---TPATPKVKSGVRR 641
            P + P        T S + E+ T     P   + M  P  +TT      +T    S    
Sbjct: 808  PSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHT 867

Query: 642  AEPATPVVKAVPEAPKG--------------------GEAEDLVGKPYSQDAS------- 674
               A     A+ E P                      G +E+      SQDA+       
Sbjct: 868  ISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPA 927

Query: 675  RSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPH--PPSPSEIHKVGSSMR 732
            RS  S+     ++  ISS   E T +         S   T  H  P SP+      S+  
Sbjct: 928  RSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTTS 987

Query: 733  PLLQAQGLAPSERSKPLSSGTGE--EQKQRP----HSLSITPEAFDSDEEL----EDILE 782
              +  +  + + RS+P S+ T    +    P    HS +       +D  L         
Sbjct: 988  SGVSEE--STTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 1045

Query: 783  EDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDF 842
              ++S          DTA S    GS     + ++S+    +P            T    
Sbjct: 1046 PSQESTTSHSSSGSTDTALSP---GSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGI 1102

Query: 843  M-------------RRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQE- 888
            +             R  +   S+    L+ + TA      + H T    P     P +E 
Sbjct: 1103 VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH-TTPSPPSTATAPVEES 1161

Query: 889  ------PAALPKRRLPHNATTGYEELLPEGGSAEAT------DGSGTLQGGLRRFKTIEL 936
                  P + P    P ++TT        G S ++T      D SGT             
Sbjct: 1162 TTYHRSPGSTPTTHFPASSTTS-------GHSEKSTIFHSSPDASGT------------- 1201

Query: 937  NSTGSYGHELDLGQGPDPSLDREP-ELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTS 995
              T S  H    G+G   +    P   E+ +L GS       E S+T  +S  S T+  S
Sbjct: 1202 --TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLS 1259

Query: 996  PTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLRE 1055
            P S++SL    +S+ SR         Q  + H +  P   T    SEE            
Sbjct: 1260 PASMTSLGVGEESTTSR--------SQPGSTHSTVSPASTTTPGLSEESTT--------- 1302

Query: 1056 QEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEM 1115
                       + S++R +             E +  P S  + +    PT    + A  
Sbjct: 1303 -----------VYSSSRGST------------ETTVFPHSTTTSVHGEEPTTFHSRPAST 1339

Query: 1116 EELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTP 1175
               H +  +E S +  L  E+ A  G P+   ++G    L T       T  PS S +T 
Sbjct: 1340 ---HTTLFTEDSTTSGLTEESTAFPGSPAST-QTGLPATLTTADLGEESTTFPSSSGSTG 1395

Query: 1176 SSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDR 1235
            +   P +S           + L       +  +      P  PT P    S   + TT  
Sbjct: 1396 TKLSPARSTTSGLVGESTPSRL-------SPSSTETTTLPGSPTTP----SLSEKSTTF- 1443

Query: 1236 EYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAES 1295
             Y     P A  +PA+  ++   E   TS S    +  S+   AF  D           +
Sbjct: 1444 -YTSPRSPDATLSPATTTSSGVSEESSTSHS----QPGSTHTTAFP-DSTTTSDLSQEPT 1497

Query: 1296 AYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPL- 1354
                        L+PG++        S +  +S   +   ++PD  +T     E   P  
Sbjct: 1498 TSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLV-EASTPTH 1556

Query: 1355 ----KLHSS--PASPSSAS-KEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSE 1407
                 LH++  PAS +SA  +E    F   P +  TT   P P G      T A+P    
Sbjct: 1557 SSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT---PSPPG------TTAAPV--- 1604

Query: 1408 RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQ-P 1466
                 S+T HS   S  T ++ + +  L          GR+     + +S G  GT   P
Sbjct: 1605 ---EVSTTYHSRPSSTPTTHFSASSTTL----------GRSEESTTVHSSPGATGTALFP 1651

Query: 1467 SRAYSYFASSSPPLSP-SSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPT 1525
            +R+ +      P  SP SS S   T  PG       +E ST   S   + D   SP + T
Sbjct: 1652 TRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTT 1711

Query: 1526 PSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHAS-ASTSPLCSP 1584
             S +  + T +  RP         S+    F   T     S ++   H+S  ST    SP
Sbjct: 1712 SSGVSEESTTSHSRPG--------STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP 1763

Query: 1585 TETQPTTHGYSQTT----PPSV-SQLPPEPPGPPGF----PRVPSAGADGPLALYGWGAL 1635
              T  ++ G   TT    P S  + L P+     G       V S+       L   G+ 
Sbjct: 1764 GSTTASSLGPESTTFHSSPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGST 1823

Query: 1636 PAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP---------IILTDQGMDL 1686
              +  S     S P +    P P T  +A V+L T    +P            T  G   
Sbjct: 1824 TRQGES-TTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSE 1882

Query: 1687 TSLAVEARKYGLALDPIPGRQSTA 1710
             S  V +     A  P P R +T+
Sbjct: 1883 ESTTVHSSPVATATTPSPARSTTS 1906



 Score = 95.9 bits (237), Expect = 7e-19
 Identities = 358/1668 (21%), Positives = 525/1668 (31%), Gaps = 292/1668 (17%)

Query: 92   ASPTPKQASATTPGHESPRETRAQ-GPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGS 150
            ++ TP  +  +T  H SPR       PA   + G        S ++      +  PD  +
Sbjct: 2039 STTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGVSEE-STTSHSRPGSTHTTAFPDSTT 2097

Query: 151  TPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLT 210
            TP            P ST   +   S  TS PSQ +    T  H+          +P  T
Sbjct: 2098 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES----TTSHS----------SPGST 2143

Query: 211  QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPG 270
                          AL    TTA     +      +    H+        PD   S G  
Sbjct: 2144 DT------------ALSPGSTTALSFGQESTTFHSSPGSTHTTLF-----PDSTTSSGI- 2185

Query: 271  GPQPGSR-QAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA 329
              +  +R  + T    +   PA + +P   G  +     P    T    P    AP + +
Sbjct: 2186 -VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 2244

Query: 330  TAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD-TQGQPAPSKGTPKIVF 388
            T      G+T  T    +    G      ++ ST+    P+A  T    A S  + +   
Sbjct: 2245 TTYHRSPGSTPTTHFPASSTTSGH-----SEKSTIFHSSPDASGTTPSSAHSTTSGRGES 2299

Query: 389  NDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
              +    G   + + PG    PG              P         TS   G     + 
Sbjct: 2300 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 2359

Query: 449  SKAAAKPKTMPKERAICP-LCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEK 507
            S+  +   T+       P L +    V S SP +  T    R    ++ G  PT      
Sbjct: 2360 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRP 2419

Query: 508  TEWLCLNCQTKRLLEGSLGEPTPLP-PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSG 566
                           G   E T  P  P S Q   G P   +            LG+ S 
Sbjct: 2420 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQ--TGLPATLTTAD---------LGEEST 2468

Query: 567  PLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPET 626
              P+ +    T  SP  S  S             TPS +    T              ET
Sbjct: 2469 TFPSSSGSTGTTLSPARSTTSGLVG-------ESTPSRLSPSST--------------ET 2507

Query: 627  TPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYS 686
            T  P +P   S    +E +T    +                P S DA+ SP + + +G S
Sbjct: 2508 TTLPGSPTTPS---LSEKSTTFYTS----------------PRSPDATLSPATTTSSGVS 2548

Query: 687  SDGISS-SQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSER 745
             +  +S SQ   T          DS    G    S +     GS+   LL A        
Sbjct: 2549 EESSTSHSQPGSTHTTAFP----DSTTTPGLSRHSTTSHSSPGSTDTTLLPAS------- 2597

Query: 746  SKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDD 805
                +SG  +E      S   T  A          L   ++S  +        T    D 
Sbjct: 2598 --TTTSGPSQESTTSHSSPGSTDTALSPGSTTA--LSFGQESTTFHSSPGSTHTTLFPDS 2653

Query: 806  FGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATS 865
              S      VE S+    S   P               R  +   S+    L+ + T   
Sbjct: 2654 TTSS---GIVEASTRVHSSTGSP---------------RTTLSPASSTSPGLQGESTTFQ 2695

Query: 866  GRGLAKHGTQKGGPRPRPEPSQE-------PAALPKRRLPHNATTGYEELLPEGGSAEAT 918
                + H T    P     P +E       P + P    P ++TT        G S ++T
Sbjct: 2696 THPASTH-TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTS-------GHSEKST 2747

Query: 919  ------DGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP-ELEMESLTGSP 971
                  D SGT               T S  H    G+G   +    P   E+ +L GS 
Sbjct: 2748 IFHSSPDASGT---------------TPSSAHSTTSGRGESTTSRISPGSTEITTLPGST 2792

Query: 972  EDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHG 1031
                  E S+T  +S  S T+  SP S++SL    +S+ SR         Q  + H +  
Sbjct: 2793 TTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR--------SQPGSTHSTVS 2844

Query: 1032 PLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSK 1091
            P   T    SEE                  V      ST                 E + 
Sbjct: 2845 PASTTTPGLSEESTT---------------VYSSSPGST-----------------ETTV 2872

Query: 1092 TPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGS 1151
             P S  + +    PT    + A     H +  +E S +  L  E+ A  G P+   ++G 
Sbjct: 2873 FPRSTTTSVRGEEPTTFHSRPAST---HTTLFTEDSTTSGLTEESTAFPGSPAST-QTGL 2928

Query: 1152 EYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGP 1211
               L T       T  PS S +T ++  P +S           + L       +  +   
Sbjct: 2929 PATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGESTPSRL-------SPSSTET 2981

Query: 1212 HGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMR 1271
               P  PT P    S   + TT   Y     P A  +PA+  ++   E   TS S    +
Sbjct: 2982 TTLPGSPTTP----SLSEKSTTF--YTSPRSPDATLSPATTTSSGVSEESSTSHS----Q 3031

Query: 1272 QASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDS 1331
              S+   AF  D           +A           L+PG++        S +  +S   
Sbjct: 3032 PGSTHTTAFP-DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 3090

Query: 1332 SGGRVIPDVRVTQHFAKETQDPL-----KLHSS--PASPSSAS-KEIGMPFSQGPGTPAT 1383
            +   ++PD  +T     E   P       LH++  PAS +SA  +E    F   P +  T
Sbjct: 3091 TETTLLPDDTITSGLV-EASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDT 3149

Query: 1384 TAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLA 1443
            T   P P G      T A+P         S+T HS   S  T ++ + +  L        
Sbjct: 3150 T---PSPPG------TTAAPV------EVSTTYHSRPSSTPTTHFSASSTTL-------- 3186

Query: 1444 AAGRAAREKPLSASDGEGGTPQ-PSRAYSYFASSSPPLSP-SSPSESPTFSPGKMGPRAT 1501
              GR+     + +S G  GT   P+R+ +      P  SP SS S   T  PG       
Sbjct: 3187 --GRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGL 3244

Query: 1502 AEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITL 1561
            +E ST   S   + D   SP + T S +  + T +  RP         S+    F   T 
Sbjct: 3245 SEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPG--------STHTTAFPGSTT 3296

Query: 1562 ASDASSQTRMVHAS-ASTSPLCSPTETQPTTHGYSQTT----PPSV-SQLPPEPPGPPGF 1615
                S ++   H+S  ST    SP  T  ++ G   TT    P S  + L P+     G 
Sbjct: 3297 MPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTASGL 3356

Query: 1616 ----PRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTA 1671
                  V S+       L   G+   +  S     S P +    P P T  +A V+L T 
Sbjct: 3357 LEASTPVHSSTGSPHTTLSPAGSTTRQGES-TTFQSWPNSKDTTPAPPTTTSAFVELSTT 3415

Query: 1672 VKPTP---------IILTDQGMDLTSLAVEARKYGLALDPIPGRQSTA 1710
               +P            T  G    S  V +     A  P P R +T+
Sbjct: 3416 SHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 3463



 Score = 91.7 bits (226), Expect = 1e-17
 Identities = 364/1766 (20%), Positives = 568/1766 (32%), Gaps = 263/1766 (14%)

Query: 71   PG-PGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTL 129
            PG P ST   L       +    S T   +S +T    SP  +   G  G+    P R  
Sbjct: 2918 PGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGEST--PSRLS 2975

Query: 130  QVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTS-----DLTSTPSQ 184
               + T     SP+ +P      T+ Y+ P+    P +TL P   TS     + +++ SQ
Sbjct: 2976 PSSTETTTLPGSPT-TPSLSEKSTTFYTSPRS---PDATLSPATTTSSGVSEESSTSHSQ 3031

Query: 185  PNFNTCTQCHNKVCNQCGFNPNP---HLTQ--VKEWLCLNCQMQRALGMDMTTAPRSKSQ 239
            P  +T T          G +  P   H +Q   +  L        +LG   TT   S   
Sbjct: 3032 PG-STHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGD 3090

Query: 240  QQLH-------SPALSPAHSPAKQPLGK------PDQERSRGPGGPQPGSRQAETARATS 286
             +         +  L  A +P     G       P    S G        +   ++  T+
Sbjct: 3091 TETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTT 3150

Query: 287  VPGPAQAAAPPEVGRVSPQPPQPT----------------KPSTAEPRPPA-GEA--PAK 327
               P   AAP EV       P  T                + +T    P A G A  P +
Sbjct: 3151 PSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTR 3210

Query: 328  SATAVPAGLGATEQTQEGLTGKLFGLG----ASLLTQASTLMSVQPEADTQGQPAPSKGT 383
            SAT+V  G   T     G T      G    A L  +++T  S     DT   PA +  +
Sbjct: 3211 SATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSS 3270

Query: 384  PKIVFNDAS-KEAGPKPLGSGPGPGPAPGAKTEPGA-RMGPGSGPGALPKTGGTTSPKHG 441
                 +  S    G     + PG    PG   E  A    PGS    L     T S    
Sbjct: 3271 GVSEESTTSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGP 3330

Query: 442  RAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPT 501
             +    +   + +   +P       L +A   V S + + + T +              T
Sbjct: 3331 ESTTFHSGPGSTETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPA----------GST 3380

Query: 502  PHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQ--PPVGAPHRASGTSPLKQKGPQ 559
                E T +             +  + TP PP T+          H +  ++P       
Sbjct: 3381 TRQGESTTFQSWP---------NSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSAS 3431

Query: 560  G--LGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQ-----EKKTRV 612
               LG+        +SP++T  +P P++++       ++    +P S Q     E  T  
Sbjct: 3432 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS 3491

Query: 613  PTKAEPMPKPPPETTPTPATPKVKSGV------RRAEPATPVVKAVPEAPK-GGEAEDLV 665
                E        T    + P   S +        + P +      P++    G +E+  
Sbjct: 3492 GRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEEST 3551

Query: 666  GKPYSQDAS-------RSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPH- 717
                SQDA+       RS  S+     ++  ISS   E T +         S   T  H 
Sbjct: 3552 ASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHS 3611

Query: 718  -PPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRP----HSLSITPEAFD 772
             P SP+      S+    +  +      R     +    +    P    HS +       
Sbjct: 3612 SPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGS 3671

Query: 773  SDEELEDILEEDEDSA-EWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPP 831
            +D  L         S+ E         + +++   GS     + ++S+    SP      
Sbjct: 3672 TDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTT 3731

Query: 832  ARAAELTDEDFM-------------RRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGG 878
                  T    +             R  +   S+    L+ + TA      + H T    
Sbjct: 3732 LFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH-TTPSP 3790

Query: 879  PRPRPEPSQE-------PAALPKRRLPHNATTGYEELLPEGGSAEAT------DGSGTLQ 925
            P     P +E       P + P    P ++TT        G S ++T      D SGT  
Sbjct: 3791 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTS-------GHSEKSTIFHSSPDASGT-- 3841

Query: 926  GGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP-ELEMESLTGSPEDRSRGEHSSTLP 984
                         T S  H    G+G   +    P   E+ +L GS       E S+T  
Sbjct: 3842 -------------TPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFY 3888

Query: 985  ASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEE 1044
            +S  S T+  SP S++SL    +S+ SR         Q  + H +  P   T    SEE 
Sbjct: 3889 SSPRSPTTTLSPASMTSLGVGEESTTSR--------SQPGSTHSTVSPASTTTPGLSEES 3940

Query: 1045 ELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDAS 1104
                             V      ST                 E +  P S  + +    
Sbjct: 3941 TT---------------VYSSSPGST-----------------ETTVFPRSTTTSVRREE 3968

Query: 1105 PTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSP 1164
            PT    + A     H +  +E S +  L  E+ A  G P+   ++G    L T       
Sbjct: 3969 PTTFHSRPAST---HTTLFTEDSTTSGLTEESTAFPGSPAST-QTGLPATLTTADLGEES 4024

Query: 1165 TETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGL 1224
            T  PS S +T +   P +S           + L       +  +      P  PT P   
Sbjct: 4025 TTFPSSSGSTGTKLSPARSTTSGLVGESTPSRL-------SPSSTETTTLPGSPTTP--- 4074

Query: 1225 GSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDK 1284
             S   + TT   Y     P A  +PA+  ++   E   TS S    +  S+   AF  D 
Sbjct: 4075 -SLSEKSTTF--YTSPRSPDATLSPATTTSSGVSEESSTSHS----QPGSTHTTAFP-DS 4126

Query: 1285 KKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQ 1344
                      +            L+PG++        S +  +S   +   ++PD  +T 
Sbjct: 4127 TTTSGLSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITS 4186

Query: 1345 HFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-P 1403
               +         S+P   S+ S    +       TPA++       GL     T  S P
Sbjct: 4187 GLVEA--------STPTHSSTGSLHTTL-------TPASST----STGLQEESTTFQSWP 4227

Query: 1404 AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT 1463
            + S+ +PSP ST        TT +    +       +     GR+     + +S G  GT
Sbjct: 4228 SSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGT 4287

Query: 1464 PQ-PSRAYSYFASSSPPLSP-SSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSP 1521
               P+R+ +      P  SP SS S   T  PG       +E ST   S   + D   SP
Sbjct: 4288 ALFPTRSATSVLVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 4347

Query: 1522 GAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFM----VITLASDASSQTRMVHASAS 1577
             + T S +  + T +  RP +       SS   P +      + +S  S+ T +   S +
Sbjct: 4348 ASTTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTT 4407

Query: 1578 TSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGF----PRVPSAGADGPLALYGWG 1633
             S L   + T  ++ G ++TT      L P+     G       V S+       L   G
Sbjct: 4408 ASSLGPESTTFHSSPGSTETT------LLPDNTTASGLLEASTPVHSSTGSPHTTLSPAG 4461

Query: 1634 ALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP---------IILTDQGM 1684
            +   +  S     S P +    P P T  +A V+L T    +P            T  G 
Sbjct: 4462 STTRQGES-TTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGR 4520

Query: 1685 DLTSLAVEARKYGLALDPIPGRQSTA 1710
               S  V +     A  P P R +T+
Sbjct: 4521 SEESTTVHSSPVATATTPSPARSTTS 4546



 Score = 90.5 bits (223), Expect = 3e-17
 Identities = 424/2063 (20%), Positives = 662/2063 (32%), Gaps = 296/2063 (14%)

Query: 27   PGPGPGAGKPPSAPAGG---------GQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTS 77
            PG  P    P S+   G             A+G   S+A     G G        PGST 
Sbjct: 2251 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 2310

Query: 78   RRLDPKEPLGNQRAASPTPKQASATTPGHESPRE-TRAQGPAGQEADGPRRTLQVDSRTQ 136
                P         ++ TP  + A+T  + SPR  T    PA   + G        SR+Q
Sbjct: 2311 ITTLP--------GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE-STTSRSQ 2361

Query: 137  RSGRSPSVSPDRGSTP-TSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNF-------N 188
                  +VSP   +TP  S  S    +  P ST   +   +  TS   +          +
Sbjct: 2362 PGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPAS 2421

Query: 189  TCTQCHNKVCNQCG-------FNPNPHLTQVKEWLCLNCQMQRA-LGMDMTTAPRSKSQQ 240
            T T    +     G       F  +P  TQ      L   +  A LG + TT P S    
Sbjct: 2422 THTTLFTEDSTTSGLTEESTAFPGSPASTQTG----LPATLTTADLGEESTTFPSSSGST 2477

Query: 241  QLHSPALSPAHSPAKQPLGKPDQER--------SRGPGGPQ-PGSRQAETARATSVPGPA 291
                  LSPA S     +G+    R        +  PG P  P   +  T   TS   P 
Sbjct: 2478 ---GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 2534

Query: 292  QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLF 351
               +P      +       + ST+  +P +    A   +    GL     T     G   
Sbjct: 2535 ATLSPA----TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGST- 2589

Query: 352  GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPA-- 409
                +LL  ++T      E+ T      S  T     +  +   G +       PG    
Sbjct: 2590 --DTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT 2647

Query: 410  ---PGAKTEPG-------ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMP 459
               P + T  G            GS    L     T+    G +       A+      P
Sbjct: 2648 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSP 2707

Query: 460  KERAICPLCQAEL---NVGSKSPANY--NTCTTCRLQVCNLCGFNP-----TPHLVEKTE 509
               A  P+ ++     + GS    ++  ++ T+   +   +   +P     TP     T 
Sbjct: 2708 PSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTT 2767

Query: 510  WLCLNCQTKRLLEGSLGEPTPLP-----PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQP 564
                   T R+  GS  E T LP     P  S+          S T+ L       LG  
Sbjct: 2768 SGRGESTTSRISPGST-EITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVG 2826

Query: 565  SGPLPAKASPLSTKASPLPSKA-----SPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPM 619
                 +++ P ST ++  P+       S ++  + +S P  T ++V  + T    + E  
Sbjct: 2827 EESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEP 2886

Query: 620  P----KPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASR 675
                 +P    T         SG+     A P     P + + G    L      ++++ 
Sbjct: 2887 TTFHSRPASTHTTLFTEDSTTSGLTEESTAFP---GSPASTQTGLPATLTTADLGEESTT 2943

Query: 676  SPQSLSDTGYSSDGISSSQSEITGV-VQQEVEQLDSAGVTGPHPPSPSEIHKVGSSM--R 732
             P S   TG +     S+ S + G      +    +   T P  P+   + +  ++    
Sbjct: 2944 FPSSSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTS 3003

Query: 733  PLLQAQGLAPSERSKPLSSGTGEEQK---QRPHSLSITPEAFDSDEELEDILEEDEDSAE 789
            P      L+P+  +   SSG  EE      +P S   T  AF        + +E   S  
Sbjct: 3004 PRSPDATLSPATTT---SSGVSEESSTSHSQPGSTHTT--AFPDSTTTSGLSQEPTAS-- 3056

Query: 790  WRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILE 849
                   Q + E++   GS       + S+    SP   +       L  +D +   ++E
Sbjct: 3057 ----HSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTE-----TTLLPDDTITSGLVE 3107

Query: 850  MSAEEDNLEED-DTATSGRGLAKHGTQKGGPRPRPEPSQE---PAALPKRRLPHNATTGY 905
             S    +      T  +       G Q+     +  PS     P+       P   +T Y
Sbjct: 3108 ASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTY 3167

Query: 906  EELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP----- 960
                P          S T  G      T+  +S G+ G  L   +     L  EP     
Sbjct: 3168 HSR-PSSTPTTHFSASSTTLGRSEESTTVH-SSPGATGTALFPTRSATSVLVGEPTTSPI 3225

Query: 961  ---ELEMESLTGSPEDRSRGEHSSTLPAS--TPSYTSGTSPTSLSSLEEDSDSSPSR--- 1012
                 E  +L GS       E S+T  +S  +P  T   + T+ S + E+S +S SR   
Sbjct: 3226 SSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS 3285

Query: 1013 --------RQRLEEAKQQRKARHRSHGPLLPTIED-SSEEEELREEEELLREQEKMREVE 1063
                       +    Q+  A H S G    T+   S+    L  E           E  
Sbjct: 3286 THTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETT 3345

Query: 1064 QQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSC 1123
                 +TA         + +      + +P + LSP   A  T    ++   +    S  
Sbjct: 3346 LLPDNTTASGLLEASTPVHSS-----TGSPHTTLSP---AGSTTRQGESTTFQSWPNSKD 3397

Query: 1124 SEYSPSPSLDSEAE---ALDGGPSRL---YKSGSEYNLPTFMSLYSPTETPSGSSTTPSS 1177
            +  +P  +  +  E      G PS     + S S   L       +   +P  ++TTPS 
Sbjct: 3398 TTPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSP 3457

Query: 1178 GRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREY 1237
             R   S       ++ ++       G       P    S  T  RG  S     +T    
Sbjct: 3458 ARSTTSG------LVEESTTYHSSPGSTQTMHFPE---SDTTSGRGEESTTSHSSTTHTI 3508

Query: 1238 GQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAY 1297
              A          S  +A+ EE      S          D +    + +E       +A 
Sbjct: 3509 SSAP---------STTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES------TAS 3553

Query: 1298 MDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLH 1357
                   G  + P  S T +    S ++P SS S     +P    T   ++++      H
Sbjct: 3554 HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS---TTFH 3610

Query: 1358 SSPASP----------SSASKEIGMPFSQGPGTPATTAV--APCPAGLPRGYMTP-ASPA 1404
            SSP SP          SS   E        PG+  TTA   +    GL R   T  +SP 
Sbjct: 3611 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 3670

Query: 1405 GSERSPSPSSTAHS-YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT 1463
             ++ +  P+ST  S      TT++  S + D   +P    A           +S G   T
Sbjct: 3671 STDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHT 3730

Query: 1464 P--QPSRAYSYFASSSPPLSPSSPSESPTFSP-GKMGPRATAEFSTQTPSPAPASDMPRS 1520
                 S   S    +S  +  S+ S   T SP     P    E +     PA     P  
Sbjct: 3731 TLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSP 3790

Query: 1521 PGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSP 1580
            P   T +P+    T      STP   +  SS           S  S ++ + H+S   S 
Sbjct: 3791 PSTAT-APVEESTTYHRSPGSTPTTHFPASS---------TTSGHSEKSTIFHSSPDASG 3840

Query: 1581 LCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENI 1640
              +P+    TT G  ++T   +S    E    PG    P   ++     Y     P   +
Sbjct: 3841 -TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL-SEASTTFYSSPRSPTTTL 3898

Query: 1641 SLCRISSV-----PGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARK 1695
            S   ++S+       TSR +PG            T    +P   T  G+   S  V +  
Sbjct: 3899 SPASMTSLGVGEESTTSRSQPG-----------STHSTVSPASTTTPGLSEESTTVYSSS 3947

Query: 1696 YGLALDPIPGRQSTA----VQPLVINLN-AQEHTFLAT--ATTVSITMASSVFMAQQKQP 1748
             G     +  R +T      +P   +   A  HT L T  +TT  +T  S+ F       
Sbjct: 3948 PGSTETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP------ 4001

Query: 1749 VVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG------RPREAKFARY 1802
               G P  ++       G P  L      E++  T P  SG  G      R   +     
Sbjct: 4002 ---GSPASTQT------GLPATLTTADLGEEST-TFPSSSGSTGTKLSPARSTTSGLVGE 4051

Query: 1803 NLPNQVAPLARRDVLITQMGTAQSIGLKPGPV------PEPGAEPHRATPAEL-----RS 1851
            + P++++P +     +    T  S+  K          P+    P   T + +      S
Sbjct: 4052 STPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTS 4111

Query: 1852 HALPGARKPHTVVVQMGEGTAGTVTTLLPEEPA------GALDLTGMRPESQLACCDMVY 1905
            H+ PG+   HT        T+G     L +EP       G+ + T + P S  A      
Sbjct: 4112 HSQPGS--THTTAFPDSTTTSG-----LSQEPTTSHSSQGSTEAT-LSPGSTTAS----- 4158

Query: 1906 KLPFGSSCTGTFHPAPSVPEKSM 1928
                G   T TFH +P   E ++
Sbjct: 4159 --SLGQQST-TFHSSPGDTETTL 4178



 Score = 89.0 bits (219), Expect = 9e-17
 Identities = 341/1633 (20%), Positives = 515/1633 (31%), Gaps = 215/1633 (13%)

Query: 54   STAVPPVPGPGPGPGPGP-------GPGSTSRRLDPKEPLGNQRAASPTPKQASA-TTPG 105
            ST     PG    PG           PGST   L P    G+  A+S  P+  +  ++PG
Sbjct: 1728 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP----GSTTASSLGPESTTFHSSPG 1783

Query: 106  HES----PRETRAQG------PAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSP 155
                   P  T A G      P       P  TL     T R G S +      S P+S 
Sbjct: 1784 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQ----SWPSSK 1839

Query: 156  YSVPQIAPLPSSTLCPICKTS--DLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVK 213
             ++P   P  +S    +  TS    +STP+     T     +    +   +   H + V 
Sbjct: 1840 DTMPA-PPTTTSAFVELSTTSHGSPSSTPT-----THFSASSTTLGRSEESTTVHSSPVA 1893

Query: 214  EWLCLNCQMQRALGM-DMTTAPRSK--SQQQLHSPALSPAHSPAKQPLGKPDQERSRGPG 270
                 +       G+ + +TA  S   S Q +H P  S A   +++              
Sbjct: 1894 TATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISS 1953

Query: 271  GPQPGSRQAETARAT-SVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA 329
             P   S   E   +  S PG       P+    S +  + T   +++        PA+S 
Sbjct: 1954 PPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARST 2013

Query: 330  TAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFN 389
            T+V  G   T     G       +  + L  ++T   +  ++ T      S  T     +
Sbjct: 2014 TSVLLGESTTSPISSG------SMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAS 2067

Query: 390  DASKEAGPKPLGSGPGPGPA-----PGAKTEPG-------ARMGPGSGPGALPKTGGTTS 437
              S     +   S   PG       P + T PG       +   PGS    L     TTS
Sbjct: 2068 TTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTS 2127

Query: 438  PKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCG 497
                    Q ++ + + P +   + A+ P     L+ G +S   +++            G
Sbjct: 2128 -----GPSQESTTSHSSPGS--TDTALSPGSTTALSFGQESTTFHSS-----------PG 2169

Query: 498  FNPTPHLVEKTEWLCLNCQTKRLLEGSLGEP-TPLPPPTSQQPPVGAPHRASGTSPLKQK 556
               T    + T    +  +    +  S G P T L P +S  P +     A  T P    
Sbjct: 2170 STHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTH 2228

Query: 557  GPQGLGQPSGPLPAKASPLSTKASPLPSKA----SPQAKPLRASEPSKTPSSVQEKKTRV 612
                            SP ST  +P+        SP + P      S T S   EK T  
Sbjct: 2229 -------------TTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIF 2275

Query: 613  PTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVP---EAPKGGEAE-DLVGKP 668
             +  +     P     T  + + +S   R  P +  +  +P     P   EA       P
Sbjct: 2276 HSSPDASGTTPSSAHST-TSGRGESTTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSP 2334

Query: 669  YSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVG 728
             S   + SP S++  G   +  +S      G     V    +        P  SE     
Sbjct: 2335 RSPTTTLSPASMTSLGVGEESTTSRSQ--PGSTHSTVSPASTT------TPGLSEESTTV 2386

Query: 729  SSMRPLLQAQGLAPSERSKPLSSGTGEEQ---KQRPHSLSITPEAFDSDEELEDILEED- 784
             S  P      + P     P +S  GEE      RP S   T   F  D     + EE  
Sbjct: 2387 YSSSPGSTETTVFP---RTPTTSVRGEEPTTFHSRPASTHTT--LFTEDSTTSGLTEEST 2441

Query: 785  -------EDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAEL 837
                                D  E S  F S         S+   LSP          E 
Sbjct: 2442 AFPGSPASTQTGLPATLTTADLGEESTTFPSS------SGSTGTTLSPARSTTSGLVGES 2495

Query: 838  TDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRL 897
            T       ++   S E   L    T  S   L++  T        P+ +  PA      +
Sbjct: 2496 TPS-----RLSPSSTETTTLPGSPTTPS---LSEKSTTFYTSPRSPDATLSPATTTSSGV 2547

Query: 898  PHNATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLD 957
               ++T + +    G +        T   GL R  T   +S GS    L           
Sbjct: 2548 SEESSTSHSQ---PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL----------- 2593

Query: 958  REPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS--DSSPSRRQR 1015
                L   + T  P   S   HSS  P ST +  S  S T+LS  +E +   SSP     
Sbjct: 2594 ----LPASTTTSGPSQESTTSHSS--PGSTDTALSPGSTTALSFGQESTTFHSSPG---- 2643

Query: 1016 LEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTR 1075
                         +H  L P   DS+    + E    +               ST+   +
Sbjct: 2644 ------------STHTTLFP---DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQ 2688

Query: 1076 RDKEELRAQ-RRRERSKTPPSN-LSPIEDASPTEELRQAAEMEELHRSSCS--EYSPSPS 1131
             +    +        + +PPS   +P+E+++       +        SS +      S  
Sbjct: 2689 GESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTI 2748

Query: 1132 LDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETP----SGSSTTPSSGRPLKSAEEA 1187
              S  +A    PS  + + S     T  S  SP  T      GS+TTP     L  A   
Sbjct: 2749 FHSSPDASGTTPSSAHSTTSGRGEST-TSRISPGSTEITTLPGSTTTPG----LSEASTT 2803

Query: 1188 YEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG 1247
            +    R            +   G     S+        +     TT     + +      
Sbjct: 2804 FYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSS 2863

Query: 1248 TPASLGAAVYEEILQTS-----QSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMK 1302
            +P S    V+     TS      +    R AS+    F ED       L  ES       
Sbjct: 2864 SPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG--LTEESTAFPGSP 2921

Query: 1303 QNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS--- 1359
             +     P T  T      S + P+SS S+G  + P    T     E+  P +L  S   
Sbjct: 2922 ASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES-TPSRLSPSSTE 2980

Query: 1360 ----PASPSSAS-KEIGMPFSQGPGTPATT--AVAPCPAGLPRGYMTPASPAGSERSPS- 1411
                P SP++ S  E    F   P +P  T        +G+     T  S  GS  + + 
Sbjct: 2981 TTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAF 3040

Query: 1412 PSSTAHSYGHSPTTANYGSQ-TEDLPQAPSGLAAAGRAAREKPLSASDGEGGTP--QPSR 1468
            P ST  S      TA++ SQ + +   +P    A+    +     +S G+  T       
Sbjct: 3041 PDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDT 3100

Query: 1469 AYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSP 1528
              S    +S P   S+ S   T +P         E ST   S   +SD   SP   T +P
Sbjct: 3101 ITSGLVEASTPTHSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAP 3160

Query: 1529 MVAQGTQTPHRPSTPRLVWQESSQ---EAPFMVITLASDASSQTRMVHASASTSPLCSPT 1585
            +    T      STP   +  SS     +       +S  ++ T +    ++TS L    
Sbjct: 3161 VEVSTTYHSRPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEP 3220

Query: 1586 ETQPTTHGYSQTT 1598
             T P + G ++TT
Sbjct: 3221 TTSPISSGSTETT 3233



 Score = 88.6 bits (218), Expect = 1e-16
 Identities = 437/2083 (20%), Positives = 648/2083 (31%), Gaps = 336/2083 (16%)

Query: 27   PGPGPGAGKPPSAPAGG---------GQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTS 77
            PG  P    P S+   G             A+G   S+A     G G        PGST 
Sbjct: 1168 PGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTE 1227

Query: 78   RRLDPKEPLGNQRAASPTPKQASATTPGHESPRE-TRAQGPAGQEADGPRRTLQVDSRTQ 136
                P         ++ TP  + A+T  + SPR  T    PA   + G        SR+Q
Sbjct: 1228 ITTLP--------GSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE-STTSRSQ 1278

Query: 137  RSGRSPSVSPDRGSTP------TSPYS----VPQIAPLPSSTLCPICKTSDLT--STPSQ 184
                  +VSP   +TP      T+ YS      +    P ST   +      T  S P+ 
Sbjct: 1279 PGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAS 1338

Query: 185  PN---FNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRA-LGMDMTTAPRSKSQQ 240
             +   F   +           F  +P  TQ      L   +  A LG + TT P S    
Sbjct: 1339 THTTLFTEDSTTSGLTEESTAFPGSPASTQTG----LPATLTTADLGEESTTFPSSSGST 1394

Query: 241  QLHSPALSPAHSPAKQPLGK--------PDQERSRGPGGP--------------QPGSRQ 278
                  LSPA S     +G+           E +  PG P               P S  
Sbjct: 1395 ---GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPD 1451

Query: 279  AETARAT--------------SVPGPAQAAAPPEVGRVSPQPPQPT--------KPSTAE 316
            A  + AT              S PG     A P+    S    +PT          +T  
Sbjct: 1452 ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEATLS 1511

Query: 317  PRPPAGEAPAKSATAVPAGLGATEQT---QEGLTGKLF-----------GLGASLLTQAS 362
            P      +  + +T   +  G TE T    + +T  L             L  +L   +S
Sbjct: 1512 PGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASS 1571

Query: 363  TLMSVQPEADT-QGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMG 421
            T   +Q E+ T Q  P+ S  TP                 S PG   AP  +        
Sbjct: 1572 TSAGLQEESTTFQSWPSSSDTTP-----------------SPPGTTAAP-VEVSTTYHSR 1613

Query: 422  PGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPAN 481
            P S P        TT  +   +    +S  A      P   A   L      VG  + + 
Sbjct: 1614 PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVL------VGEPTTSP 1667

Query: 482  YNTCTTCRLQVCNLCGFNPTPHLVEK--TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
             ++ +T   +   L G   T  L EK  T +         L   S          T+   
Sbjct: 1668 ISSGST---ETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS 1724

Query: 540  PVGAPHR----ASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK-----ASPQA 590
              G+ H      S T P   +         G      SP ST AS L  +     +SP +
Sbjct: 1725 RPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGS 1784

Query: 591  KPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVK 650
                    + T S + E  T V +         P TT +PA    + G      + P  K
Sbjct: 1785 TETTLLPDNTTASGLLEASTPVHSST-----GSPHTTLSPAGSTTRQGESTTFQSWPSSK 1839

Query: 651  AVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDS 710
                AP    +  +     S  +  SP S   T +S+   +  +SE       E   + S
Sbjct: 1840 DTMPAPPTTTSAFV---ELSTTSHGSPSSTPTTHFSASSTTLGRSE-------ESTTVHS 1889

Query: 711  AGVTGPHPPSPSEIHKVG--SSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITP 768
            + V     PSP+     G          + G   +      S+ +G  ++ R  S S T 
Sbjct: 1890 SPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRT-SHSSTT 1948

Query: 769  EAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPP 828
                S       L E+  S               S     +        SS+     +  
Sbjct: 1949 HTISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTI-- 2006

Query: 829  QPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQE 888
              PAR+             +   + E       T T G    K  T    PR  P  +  
Sbjct: 2007 VLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLS-EKSTTFHSSPR-SPATTLS 2064

Query: 889  PAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDL 948
            PA+     +   +TT +      G +        T   GL R  T   +S GS    L  
Sbjct: 2065 PASTTSSGVSEESTTSHSR---PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTL-- 2119

Query: 949  GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDS-- 1006
                         L   + T  P   S   HSS  P ST +  S  S T+LS  +E +  
Sbjct: 2120 -------------LPASTTTSGPSQESTTSHSS--PGSTDTALSPGSTTALSFGQESTTF 2164

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQR 1066
             SSP                  +H  L P   DS+    + E    +             
Sbjct: 2165 HSSPG----------------STHTTLFP---DSTTSSGIVEASTRVHSSTGSPRTTLSP 2205

Query: 1067 IRSTARKTRRDKEELRAQ-RRRERSKTPPSN-LSPIEDASPTEELRQAAEMEELHRSSCS 1124
              ST+   + +    +        + +PPS   +P+E+++       +        SS +
Sbjct: 2206 ASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTT 2265

Query: 1125 --EYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETP----SGSSTTPSSG 1178
                  S    S  +A    PS  + + S     T  S  SP  T      GS+TTP   
Sbjct: 2266 SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGEST-TSRISPGSTEITTLPGSTTTPG-- 2322

Query: 1179 RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG 1238
              L  A   +    R            +   G     S+        +     TT     
Sbjct: 2323 --LSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLS 2380

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTS-----QSIVRMRQASSRDLAFAEDKKKEKQFLNA 1293
            + +      +P S    V+     TS      +    R AS+    F ED       L  
Sbjct: 2381 EESTTVYSSSPGSTETTVFPRTPTTSVRGEEPTTFHSRPASTHTTLFTEDSTTSG--LTE 2438

Query: 1294 ESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
            ES        +     P T  T      S + P+SS S+G  + P    T     E+  P
Sbjct: 2439 ESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSPARSTTSGLVGES-TP 2497

Query: 1354 LKLHSS-------PASPSSAS-KEIGMPFSQGPGTPATT--AVAPCPAGLPRGYMTPASP 1403
             +L  S       P SP++ S  E    F   P +P  T        +G+     T  S 
Sbjct: 2498 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 2557

Query: 1404 AGSERSPS--PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEG 1461
             GS  + +   S+T        TT++    + D    P+    +G +       +S G  
Sbjct: 2558 PGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGST 2617

Query: 1462 GT---PQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMP 1518
             T   P  + A S F   S     S  S   T  P         E ST+  S   +    
Sbjct: 2618 DTALSPGSTTALS-FGQESTTFHSSPGSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTT 2676

Query: 1519 RSPGAPTPSPMVAQGT----------QTPHRPSTPRLVWQESS--QEAP-------FMVI 1559
             SP + T   +  + T           TP  PST     +ES+    +P       F   
Sbjct: 2677 LSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPAS 2736

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVP 1619
            +  S  S ++ + H+S   S   +P+    TT G  ++T   +S    E    PG    P
Sbjct: 2737 STTSGHSEKSTIFHSSPDASG-TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTP 2795

Query: 1620 SAGADGPLALYGWGALPAENISLCRISSV-----PGTSRVEPGPRTPGTAVVDLRTAVKP 1674
               ++     Y     P   +S   ++S+       TSR +PG            T    
Sbjct: 2796 GL-SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPG-----------STHSTV 2843

Query: 1675 TPIILTDQGMDLTSLAVEARKYGLALDPIPGRQST----AVQPLVINLN-AQEHTFLAT- 1728
            +P   T  G+   S  V +   G     +  R +T      +P   +   A  HT L T 
Sbjct: 2844 SPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEEPTTFHSRPASTHTTLFTE 2903

Query: 1729 -ATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYR 1787
             +TT  +T  S+ F          G P  ++       G P  L      E++  T P  
Sbjct: 2904 DSTTSGLTEESTAFP---------GSPASTQT------GLPATLTTADLGEEST-TFPSS 2947

Query: 1788 SGPRG------RPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPV------P 1835
            SG  G      R   +     + P++++P +     +    T  S+  K          P
Sbjct: 2948 SGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSP 3007

Query: 1836 EPGAEPHRATPAEL-----RSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLT 1890
            +    P   T + +      SH+ PG+   HT        T+G     L +EP  +    
Sbjct: 3008 DATLSPATTTSSGVSEESSTSHSQPGS--THTTAFPDSTTTSG-----LSQEPTASHSSQ 3060

Query: 1891 G-----MRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSM 1928
            G     + P S  A          G   T TFH +P   E ++
Sbjct: 3061 GSTEATLSPGSTTAS-------SLGQQST-TFHSSPGDTETTL 3095



 Score = 79.0 bits (193), Expect = 9e-14
 Identities = 326/1631 (19%), Positives = 502/1631 (30%), Gaps = 236/1631 (14%)

Query: 92   ASPTPKQASATTPGHESPRETRAQ-GPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGS 150
            ++ TP  +  +T  H SPR       PA   + G        SR++      +  PD  +
Sbjct: 956  STTTPGLSERSTTFHSSPRSPATTLSPASTTSSGVSEE-STTSRSRPGSTHTTAFPDSTT 1014

Query: 151  TPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLT 210
            TP            P ST   +   S  TS PSQ +    T  H+               
Sbjct: 1015 TPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQES----TTSHSS-------------- 1056

Query: 211  QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPG 270
                    +     AL    TTA     +           H+        PD   S G  
Sbjct: 1057 --------SGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLF-----PDSTTSSGI- 1102

Query: 271  GPQPGSR-QAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA 329
              +  +R  + T    +   PA + +P   G  +     P    T    P    AP + +
Sbjct: 1103 -VEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEES 1161

Query: 330  TAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD-TQGQPAPSKGTPKIVF 388
            T      G+T  T    +    G      ++ ST+    P+A  T    A S  + +   
Sbjct: 1162 TTYHRSPGSTPTTHFPASSTTSGH-----SEKSTIFHSSPDASGTTPSSAHSTTSGRGES 1216

Query: 389  NDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
              +    G   + + PG    PG              P         TS   G     + 
Sbjct: 1217 TTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSR 1276

Query: 449  SKAAAKPKTMPKERAICP-LCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEK 507
            S+  +   T+       P L +    V S S  +  T         ++ G  PT      
Sbjct: 1277 SQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRP 1336

Query: 508  TEWLCLNCQTKRLLEGSLGEPTPLP-PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSG 566
                           G   E T  P  P S Q  + A    +         P   G    
Sbjct: 1337 ASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGT 1396

Query: 567  PL-PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE 625
             L PA+++         PS+ SP +        S T  S+ EK T   T           
Sbjct: 1397 KLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSP 1456

Query: 626  TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPY-------SQDASRSPQ 678
             T T +    +S    ++P +    A P++       DL  +P        S +A+ SP 
Sbjct: 1457 ATTTSSGVSEESSTSHSQPGSTHTTAFPDSTT---TSDLSQEPTTSHSSQGSTEATLSPG 1513

Query: 679  SL--SDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQ 736
            S   S  G  S    SS  +    +  +     ++G+     P+ S    + +++ P   
Sbjct: 1514 STTASSLGQQSTTFHSSPGDTETTLLPD--DTITSGLVEASTPTHSSTGSLHTTLTPASS 1571

Query: 737  AQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQ 796
                   E +   S  +  +    P   +  P                E S  +  R   
Sbjct: 1572 TSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPV---------------EVSTTYHSRPSS 1616

Query: 797  QDTAE---SSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAE 853
              T     SS   G       V  S     + L P   A +  + +        +   + 
Sbjct: 1617 TPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPT---TSPISSGST 1673

Query: 854  EDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGG 913
            E       T T+G    K  T    PR  P+ +  PA+     +   +TT +    P   
Sbjct: 1674 ETTALPGSTTTAGLS-EKSTTFYSSPRS-PDTTLSPASTTSSGVSEESTTSHSR--PGST 1729

Query: 914  SAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPED 973
               A  GS T+ G + +  T   +S GS    L  G     SL  E      S  GS E 
Sbjct: 1730 HTTAFPGSTTMPG-VSQESTASHSSPGSTDTTLSPGSTTASSLGPE-STTFHSSPGSTET 1787

Query: 974  RSRGEH---SSTLPASTPSYTSGTSP----------------TSLSSLEEDSDSSPSRRQ 1014
                ++   S  L ASTP ++S  SP                T+  S     D+ P+   
Sbjct: 1788 TLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPT 1847

Query: 1015 RLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKT 1074
                  +     H S     PT   S+    L   EE          V      S AR T
Sbjct: 1848 TTSAFVELSTTSHGSPSST-PTTHFSASSTTLGRSEESTTVHSS--PVATATTPSPARST 1904

Query: 1075 RRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDS 1134
                 E           T   +      AS   E     E    H S+    S  PS  S
Sbjct: 1905 TSGLVEESTAYHSSPGSTQTMHFPESSTASGRSE-----ESRTSHSSTTHTISSPPSTTS 1959

Query: 1135 EAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRK 1194
               AL   P+  + S       T  + +  + T SG S   ++    + A        R 
Sbjct: 1960 ---ALVEEPTSYHSSPGS----TATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARS 2012

Query: 1195 AELLQRQQGQ----AAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPA 1250
               +   +      ++G+      P   T P   G  E   T    +     PA   +PA
Sbjct: 2013 TTSVLLGESTTSPISSGSMETTALPGSTTTP---GLSEKSTTF---HSSPRSPATTLSPA 2066

Query: 1251 SLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGG--PL 1308
            S  ++   E   TS S    R  S+   AF +         ++ +++  P   +    P 
Sbjct: 2067 STTSSGVSEESTTSHS----RPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPA 2122

Query: 1309 TPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASP----- 1363
            +  TS     +  S S+P S+D++   + P       F +E+      HSSP S      
Sbjct: 2123 STTTSGPSQESTTSHSSPGSTDTA---LSPGSTTALSFGQESTT---FHSSPGSTHTTLF 2176

Query: 1364 -----SSASKEIGMPFSQGPGTPATTAVAPCPAGLP--RGYMTP--ASPAGSERSPSPSS 1414
                 SS   E         G+P TT ++P  +  P  +G  T     PA +  +PSP S
Sbjct: 2177 PDSTTSSGIVEASTRVHSSTGSPRTT-LSPASSTSPGLQGESTAFQTHPASTHTTPSPPS 2235

Query: 1415 TAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFA 1474
            TA +     TT +    +      P+    +G + +                    S   
Sbjct: 2236 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEK--------------------STIF 2275

Query: 1475 SSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGT 1534
             SSP  S ++PS + + + G+       E +T   SP  ++++   PG+ T   +    T
Sbjct: 2276 HSSPDASGTTPSSAHSTTSGR------GESTTSRISPG-STEITTLPGSTTTPGLSEAST 2328

Query: 1535 QTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGY 1594
                 P +P                T     +S T +     ST+    P  T  T    
Sbjct: 2329 TFYSSPRSP----------------TTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPA 2372

Query: 1595 SQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRV 1654
            S TTP                                   L  E+ ++   SS PG++  
Sbjct: 2373 STTTP----------------------------------GLSEESTTV--YSSSPGSTET 2396

Query: 1655 EPGPRTPGTAV 1665
               PRTP T+V
Sbjct: 2397 TVFPRTPTTSV 2407



 Score = 67.4 bits (163), Expect = 3e-10
 Identities = 244/1213 (20%), Positives = 385/1213 (31%), Gaps = 186/1213 (15%)

Query: 525  LGEPTPLPPPTSQQPPVGAPHRASGTSP-LKQKGPQGLGQPSGPLPAKASPLSTKASPLP 583
            LGE T  P  +        P   S T+P L ++       P  P     SP ST +S + 
Sbjct: 935  LGESTTSPISSGSMETTALP--GSTTTPGLSERSTTFHSSPRSPATT-LSPASTTSSGVS 991

Query: 584  -----SKASPQAKPLRASEPSKTPSSVQEKKTRV---PTKAEPMPKPPPETTPTPATPKV 635
                 S++ P +    A   S T   +    T     P   +    P   TT  P+    
Sbjct: 992  EESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSGPSQEST 1051

Query: 636  KSGVRRAEPATPVVKAVPEAPK-GGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQ 694
             S        T +      A   G E+      P S   +  P S +     S GI  + 
Sbjct: 1052 TSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTT-----SSGIVEAS 1106

Query: 695  SEITGVVQQEVEQLDSAGVTGPHPPSPS---EIHKVGSSMRPLLQAQGLAPSERSKPLSS 751
            + +          L  A  T P     S   + H   +   P   +   AP E S     
Sbjct: 1107 TRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHR 1166

Query: 752  GTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLR 811
              G        + S T        E   I     D++          T+   +   S++ 
Sbjct: 1167 SPGSTPTTHFPASSTT----SGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRIS 1222

Query: 812  HDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAK 871
                E ++  G +  P    A     +        +   S     + E+ T +  +  + 
Sbjct: 1223 PGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGST 1282

Query: 872  HGTQKGGPRPRPEPSQEPAALPKRR--------LPHNATTGY------------------ 905
            H T        P  S+E   +             PH+ TT                    
Sbjct: 1283 HSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTT 1342

Query: 906  ---EELLPEGGSAEATDGSGT---LQGGL-RRFKTIEL--------NSTGSYGHELDLGQ 950
               E+    G + E+T   G+    Q GL     T +L        +S+GS G +L   +
Sbjct: 1343 LFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPAR 1402

Query: 951  GPDPSLDREP--------ELEMESLTGSPEDRSRGEHSSTLPAS--TPSYTSGTSPTSLS 1000
                 L  E           E  +L GSP   S  E S+T   S  +P  T   + T+ S
Sbjct: 1403 STTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSS 1462

Query: 1001 SLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMR 1060
             + E+S +S S          Q  + H +  P      DS+   +L +E       +   
Sbjct: 1463 GVSEESSTSHS----------QPGSTHTTAFP------DSTTTSDLSQEPTTSHSSQGST 1506

Query: 1061 EVEQQRIRSTARKTRRDKEELRAQRR-RERSKTPPSNLSP--IEDASPTEELRQAAEMEE 1117
            E       +TA    +      +     E +  P   ++   +E ++PT      +    
Sbjct: 1507 EATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTH-----SSTGS 1561

Query: 1118 LHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLP--------TFMSLYSPTETPS 1169
            LH +     S S  L  E+      PS    + S             T+ S  S T T  
Sbjct: 1562 LHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTH 1621

Query: 1170 GSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGP-----HGGPSQPTG-PRG 1223
             S+++ + GR  +S             L   +   +     P       G ++ T  P  
Sbjct: 1622 FSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTETTALPGS 1681

Query: 1224 LGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAED 1283
              +    + +   Y     P    +PAS  ++   E   TS S    R  S+   AF   
Sbjct: 1682 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEESTTSHS----RPGSTHTTAFPGS 1737

Query: 1284 KKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVT 1343
                     + +++  P   +   L+PG++      P S +  +S  S+   ++PD   T
Sbjct: 1738 TTMPGVSQESTASHSSPGSTDT-TLSPGSTTASSLGPESTTFHSSPGSTETTLLPD-NTT 1795

Query: 1344 QHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGT-----PATTAVAPCPAGLPRGYM 1398
                 E   P+  HSS  SP +     G    QG  T     P++    P P      ++
Sbjct: 1796 ASGLLEASTPV--HSSTGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFV 1853

Query: 1399 TPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAP--------------SGLAA 1444
              ++   S  SPS + T H +  S TT     ++  +  +P              SGL  
Sbjct: 1854 ELSTT--SHGSPSSTPTTH-FSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVE 1910

Query: 1445 AGRAAREKP----------LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG 1494
               A    P           S + G     + S + +    SSPP + S+  E PT    
Sbjct: 1911 ESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHS 1970

Query: 1495 KMGPRATAEF------------STQTPSPAPASDMPRSPGAPTPSPMVAQGTQT------ 1536
              G  AT  F            ST + S   A+     P   T S ++ + T +      
Sbjct: 1971 SPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGS 2030

Query: 1537 ------PHRPSTPRLVWQ----ESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTE 1586
                  P   +TP L  +     SS  +P   ++ AS  SS      +  ST+    P  
Sbjct: 2031 METTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTTSSGV----SEESTTSHSRPGS 2086

Query: 1587 TQPTTHGYSQTTP 1599
            T  T    S TTP
Sbjct: 2087 THTTAFPDSTTTP 2099



 Score = 66.6 bits (161), Expect = 5e-10
 Identities = 388/1938 (20%), Positives = 598/1938 (30%), Gaps = 365/1938 (18%)

Query: 54   STAVPPVPGPGPGPGPGP-------GPGSTSRRLDPKEPLGNQRAASPTPKQASATT-PG 105
            ST     PG    PG           PGST   L P    G+  A+S  P+  +  + PG
Sbjct: 3285 STHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP----GSTTASSLGPESTTFHSGPG 3340

Query: 106  HES----PRETRAQG------PAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSP 155
                   P  T A G      P       P  TL     T R G S +      S  T+P
Sbjct: 3341 STETTLLPDNTTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTP 3400

Query: 156  YSVPQIAPLPSSTLCPICKTS--DLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVK 213
                   P  +S    +  TS    +STP+  +F+  +    +       + +P  T   
Sbjct: 3401 -----APPTTTSAFVELSTTSHGSPSSTPTT-HFSASSTTLGRSEESTTVHSSPVATAT- 3453

Query: 214  EWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAK-QPLGKPDQERSRGPGGP 272
                             T +P   +   L   + +   SP   Q +  P+ + + G G  
Sbjct: 3454 -----------------TPSPARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEE 3496

Query: 273  QPGSRQAETARATSVPGPAQAAAP-----------------PEVGRVSPQPPQPTKPSTA 315
               S  + T   +S P    A                    P+    S +  + T   ++
Sbjct: 3497 STTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSS 3556

Query: 316  EPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQG 375
            +        PA+S T+V  G   T     G       +  + L  ++T   +  ++ T  
Sbjct: 3557 QDATGTIVLPARSTTSVLLGESTTSPISSG------SMETTALPGSTTTPGLSEKSTTFH 3610

Query: 376  QPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPA-----PGAKTEPG-------ARMGPG 423
                S  T     +  S     +   S   PG       P + T PG       +   PG
Sbjct: 3611 SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 3670

Query: 424  SGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYN 483
            S    L     TTS   G ++    S +++       + A+ P     L+ G +S   ++
Sbjct: 3671 STDTTLLPASTTTS---GSSQESTTSHSSSGST----DTALSPGSTTALSFGQESTTFHS 3723

Query: 484  TCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEP-TPLPPPTSQQPPVG 542
            +            G   T    + T    +  +    +  S G P T L P +S  P + 
Sbjct: 3724 SP-----------GSTHTTLFPDSTTSSGI-VEASTRVHSSTGSPRTTLSPASSTSPGLQ 3771

Query: 543  APHRASGTSPLKQKGPQGLGQPSGPLPAKA----------SPLSTKASPLPSKA------ 586
                A  T P           PS P  A A          SP ST  +  P+ +      
Sbjct: 3772 GESTAFQTHPASTHTT-----PSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHS 3826

Query: 587  --------SPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSG 638
                    SP A     S    T S   E  T   +         P +T TP   +  S 
Sbjct: 3827 EKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLSEA-ST 3885

Query: 639  VRRAEPATPVVKAVPEAPK----GGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQ 694
               + P +P     P +      G E+     +P S  ++ SP S +  G S +  +   
Sbjct: 3886 TFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYS 3945

Query: 695  SEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTG 754
            S        E      +  T      P+  H   +S    L  +           +SG  
Sbjct: 3946 SSPGST---ETTVFPRSTTTSVRREEPTTFHSRPASTHTTLFTEDST--------TSGLT 3994

Query: 755  EEQKQRPHSLSITPEAFDSDEELEDILEEDEDS----------------------AEWRR 792
            EE    P S + T     +     D+ EE                           E   
Sbjct: 3995 EESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSPARSTTSGLVGESTP 4054

Query: 793  RREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMS- 851
             R    + E++   GS       E S+    SP  P      A  T            S 
Sbjct: 4055 SRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQ 4114

Query: 852  --AEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEE-- 907
              +       D T TSG  L++  T     +   E +  P +     L   +TT +    
Sbjct: 4115 PGSTHTTAFPDSTTTSG--LSQEPTTSHSSQGSTEATLSPGSTTASSLGQQSTTFHSSPG 4172

Query: 908  -----LLPE----GGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDR 958
                 LLP+     G  EA+  + +  G L    T   +++     E    Q    S D 
Sbjct: 4173 DTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDT 4232

Query: 959  EPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEE 1018
             P     S T  P + S   HS   P+STP+     S T+L   EE +    S       
Sbjct: 4233 TPS--PPSTTAVPVEVSTTYHSR--PSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTA 4288

Query: 1019 AKQQRKARHRSHG-PLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRD 1077
                R A     G P    I   S E                         +TA  + + 
Sbjct: 4289 LFPTRSATSVLVGEPTTSPISSGSTETTALPGST-----------------TTAGLSEKS 4331

Query: 1078 KEELRAQRRRERSKTPPSNLSP-IEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEA 1136
                 + R  + + +P S  S  + + S T   R  +    +H ++    +  P +  E+
Sbjct: 4332 TTFYSSPRSPDTTLSPASTTSSGVSEESTTSHSRPGS----MHTTAFPSSTTMPGVSQES 4387

Query: 1137 EA-----------LDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSG-----RP 1180
             A           L  G +     G E    TF S    TET      T +SG      P
Sbjct: 4388 TASHSSPGSTDTTLSPGSTTASSLGPEST--TFHSSPGSTETTLLPDNTTASGLLEASTP 4445

Query: 1181 LKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQA 1240
            + S+  +    +  A    RQ         P+   + P  P    +F    TT      +
Sbjct: 4446 VHSSTGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHG-SPS 4504

Query: 1241 AQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDP 1300
            + P    + +S      EE      S V      S   +      +E    ++       
Sbjct: 4505 STPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQT 4564

Query: 1301 MKQNGGPLTPG-----------TSPTQLAAPVSFST----PTSSDSSGGRVIPDVRVTQH 1345
            M       T G           T+ T  +AP + S     PTS  SS G        T H
Sbjct: 4565 MHFPESNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGST-----ATTH 4619

Query: 1346 FAKETQDPLKLHSSPASPSS--ASKEIGMPFSQGPGTP-ATTAVAPCPAGLPRGYMTPAS 1402
            F   +    +   S AS SS  A+  I +P           +  +P  +G       P S
Sbjct: 4620 FPDSSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGS 4679

Query: 1403 ---PAGSERSP----SPSSTAHS-YGHSPTTANYGSQTEDLPQAP--------------S 1440
               P  SE+S     SPSST  + +  S TT     ++  +  +P              S
Sbjct: 4680 TTTPGLSEKSTTFHSSPSSTPTTHFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTS 4739

Query: 1441 GLAAAGRAAREKP----------LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPT 1490
            GL     A    P           S + G     + S + +    SSPP + S+  E PT
Sbjct: 4740 GLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPT 4799

Query: 1491 ---FSPGKMGPRATAEFSTQ-------------------TPSPAPASDMPR--------- 1519
                SPG +      E ST                    TP PA  +   R         
Sbjct: 4800 SYHSSPGSIATTHFPESSTTSGRSEESTASHSSPDTNGITPLPAHFTTSGRIAESTTFYI 4859

Query: 1520 --------------SPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDA 1565
                          +PG    S ++   +++P +  +P  +   S    P  + + A   
Sbjct: 4860 SPGSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAE-- 4917

Query: 1566 SSQTRMVHASASTSPLCSPTETQPTTHGYSQTT--PPSVS--------QLPPEPPG---- 1611
            S+ T    AS +TS L   + T  +  G ++TT  P S++          P   PG    
Sbjct: 4918 STHTTAFPASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALS 4977

Query: 1612 --PPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLR 1669
               P    VP    +        G+      S     S+  + +  P P +PG       
Sbjct: 4978 TVSPASTTVPGLSEESTTFYSSPGSTETTAFSHSNTMSI-HSQQSTPFPDSPG-----FT 5031

Query: 1670 TAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTA---VQPLVINLN---AQEH 1723
              V P  +  TD G + T+    +   G    P+P R + +    +P    ++       
Sbjct: 5032 HTVLPATLTTTDIGQESTAFHSSSDATGTT--PLPARSTASDLVGEPTTFYISPSPTYTT 5089

Query: 1724 TFLATATTVSITMASSVF 1741
             F A+++T  +T  S+ F
Sbjct: 5090 LFPASSSTSGLTEESTTF 5107



 Score = 62.8 bits (151), Expect = 7e-09
 Identities = 231/1104 (20%), Positives = 353/1104 (31%), Gaps = 192/1104 (17%)

Query: 901  ATTGYEELLPEGGSAEATD--GSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPD----- 953
            A T Y   L   GS E T    S T+ G     K    +        L  G  P      
Sbjct: 551  AHTSYHSSL---GSTETTHFRDSSTISGRSEESKASHSSPDAMATTVLPAGSTPSVLVGD 607

Query: 954  --PSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSS--LEEDSDSS 1009
              PS      +E  +L GS       E S+T  +S  S  +   P S++S  + E+S +S
Sbjct: 608  STPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSPDTTHLPASMTSSGVSEESTTS 667

Query: 1010 PSR-----------RQRLEEAKQQRKARHRSHGPLLPTIED-SSEEEELREEEELLREQE 1057
             SR              +    Q+  A H S GP   T+   S+    L  E      + 
Sbjct: 668  HSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRP 727

Query: 1058 KMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEE 1117
               E       +TA         + +  R           SP    SP     +  E   
Sbjct: 728  GSTETTLLPDNTTASGLLEASMPVHSSTR-----------SPHTTLSPAGSTTRQGESTT 776

Query: 1118 LHR-SSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPS 1176
             H   S  +  P+P   + A                +  P+  S  SP+  P+   +  S
Sbjct: 777  FHSWPSSKDTRPAPPTTTSA----------------FVEPSTTSHGSPSSIPTTHISARS 820

Query: 1177 SGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE 1236
            +   L      Y       + +   +      RG     S  +    + S          
Sbjct: 821  TTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHSSTTHTISS---------- 870

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESA 1296
                          S  +A+ EE      S          D +    + +E       +A
Sbjct: 871  ------------APSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEES------TA 912

Query: 1297 YMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKL 1356
                    G  + P  S T +    S ++P SS S     +P    T   ++ +      
Sbjct: 913  SHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERS---TTF 969

Query: 1357 HSSPASP----------SSASKEIGMPFSQGPGTPATTAV--APCPAGLPRGYMTP-ASP 1403
            HSSP SP          SS   E        PG+  TTA   +    GL R   T  +SP
Sbjct: 970  HSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSP 1029

Query: 1404 AGSERSPSPSSTAHS-YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGG 1462
              ++ +  P+ST  S      TT++  S + D   +P    A           ++ G   
Sbjct: 1030 GSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTH 1089

Query: 1463 TP--QPSRAYSYFASSSPPLSPSSPSESPTFSP-GKMGPRATAEFSTQTPSPAPASDMPR 1519
            T     S   S    +S  +  S+ S   T SP     P    E +     PA     P 
Sbjct: 1090 TTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS 1149

Query: 1520 SPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTS 1579
             P   T +P+    T      STP   +  SS           S  S ++ + H+S   S
Sbjct: 1150 PPSTAT-APVEESTTYHRSPGSTPTTHFPASS---------TTSGHSEKSTIFHSSPDAS 1199

Query: 1580 PLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAEN 1639
               +P+    TT G  ++T   +S    E    PG    P   ++     Y     P   
Sbjct: 1200 G-TTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGL-SEASTTFYSSPRSPTTT 1257

Query: 1640 ISLCRISSV-----PGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEAR 1694
            +S   ++S+       TSR +PG            T    +P   T  G+   S  V + 
Sbjct: 1258 LSPASMTSLGVGEESTTSRSQPG-----------STHSTVSPASTTTPGLSEESTTVYSS 1306

Query: 1695 KYGLALDPI-PGRQSTAV---QPLVINLN-AQEHTFLAT--ATTVSITMASSVFMAQQKQ 1747
              G     + P   +T+V   +P   +   A  HT L T  +TT  +T  S+ F      
Sbjct: 1307 SRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP----- 1361

Query: 1748 PVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRG------RPREAKFAR 1801
                G P  ++       G P  L      E++  T P  SG  G      R   +    
Sbjct: 1362 ----GSPASTQT------GLPATLTTADLGEEST-TFPSSSGSTGTKLSPARSTTSGLVG 1410

Query: 1802 YNLPNQVAPLARRDVLITQMGTAQSIGLKPGPV------PEPGAEPHRATPAEL-----R 1850
             + P++++P +     +    T  S+  K          P+    P   T + +      
Sbjct: 1411 ESTPSRLSPSSTETTTLPGSPTTPSLSEKSTTFYTSPRSPDATLSPATTTSSGVSEESST 1470

Query: 1851 SHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPA------GALDLTGMRPESQLACCDMV 1904
            SH+ PG+   HT           T T+ L +EP       G+ + T + P S  A     
Sbjct: 1471 SHSQPGS--THTTAF-----PDSTTTSDLSQEPTTSHSSQGSTEAT-LSPGSTTAS---- 1518

Query: 1905 YKLPFGSSCTGTFHPAPSVPEKSM 1928
                 G   T TFH +P   E ++
Sbjct: 1519 ---SLGQQST-TFHSSPGDTETTL 1538



 Score = 42.0 bits (97), Expect = 0.012
 Identities = 106/438 (24%), Positives = 154/438 (35%), Gaps = 43/438 (9%)

Query: 1310 PGTSPTQLAAPVSFSTP-TSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASK 1368
            PG + T +A P S + P  S +S+    IP    T            L     +PSS   
Sbjct: 315  PGPTHT-IAFPDSTTMPGVSQESTASHSIPGSTDTT-----------LSPGTTTPSSLGP 362

Query: 1369 EIGMPFSQGPGTPATTAVAP--CPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTA 1426
            E    F   PG   TT +      +GL        S  GS  +    S++ ++   PTT 
Sbjct: 363  E-STTFHSSPGYTKTTRLPDNTTTSGLLEASTPVHSSTGSPHTTLSPSSSTTHEGEPTTF 421

Query: 1427 NYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPS 1486
                 ++D   APSG  +A        LS +     +  P+   ++F++SS  L  S  S
Sbjct: 422  QSWPSSKDTSPAPSGTTSA-----FVKLSTTYHSSPSSTPT---THFSASSTTLGHSEES 473

Query: 1487 ESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
                 +P    P ATA  +T  P+ +  S       A   SP     TQT H P +    
Sbjct: 474  -----TPVHSSPVATA--TTPPPARSATSGHVEESTAYHRSP---GSTQTMHFPES-STT 522

Query: 1547 WQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLP 1606
               S + A F   T  + +S+ +    A A TS   S   T+ T    S T      +  
Sbjct: 523  SGHSEESATFHGSTTHTKSSTPSTTA-ALAHTSYHSSLGSTETTHFRDSSTISGRSEESK 581

Query: 1607 PEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVV 1666
                 P             P  L G       +      +++PG S  +PG     T   
Sbjct: 582  ASHSSPDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPG-STTKPGLSEKSTTFY 640

Query: 1667 DLRTAVKPT--PIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHT 1724
                +   T  P  +T  G+   S    +R         PG  ST +  L     A   +
Sbjct: 641  SSPRSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPG--STTMPGLSQESTASHSS 698

Query: 1725 FLATATTVS--ITMASSV 1740
               T TT+S   T ASS+
Sbjct: 699  PGPTDTTLSPGSTTASSL 716



 Score = 42.0 bits (97), Expect = 0.012
 Identities = 65/296 (21%), Positives = 86/296 (29%), Gaps = 48/296 (16%)

Query: 3616 SYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLG 3675
            ++H     P   L P      G      E     H R    HT   P           L 
Sbjct: 2051 TFHSSPRSPATTLSPASTTSSG----VSEESTTSHSRPGSTHTTAFPDSTTTP----GLS 2102

Query: 3676 RHEARPHSQPSSA-----PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSK----KGSR 3726
            RH    HS P S      PA      P   S+  +S P    +A    S +     + S 
Sbjct: 2103 RHSTTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQEST 2162

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
              HS P +  +   P +     G   A     S + S R   S A+S  P  Q +     
Sbjct: 2163 TFHSSPGSTHTTLFPDSTTS-SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 2221

Query: 3787 LQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSK 3846
              P     T +       P +  +AP          PG ST T   PA    +  +  S 
Sbjct: 2222 THPASTHTTPS-------PPSTATAPVEESTTYHRSPG-STPTTHFPASSTTSGHSEKST 2273

Query: 3847 GTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPG 3902
                +P                         G TP +        GES  S+I PG
Sbjct: 2274 IFHSSPDAS----------------------GTTPSSAHSTTSGRGESTTSRISPG 2307



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 64/275 (23%), Positives = 85/275 (30%), Gaps = 50/275 (18%)

Query: 3640 ASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA-----PAMPKK 3694
            +   E     H +    HT   P           L RH    HS P S      PA    
Sbjct: 2545 SGVSEESSTSHSQPGSTHTTAFPDSTTTP----GLSRHSTTSHSSPGSTDTTLLPASTTT 2600

Query: 3695 GQPGYPSSAEYSQPSRASSAYHHASDSK----KGSRQAHSGPAALQSKAEPQAQPQLQGR 3750
              P   S+  +S P    +A    S +     + S   HS P +  +   P +     G 
Sbjct: 2601 SGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS-SGI 2659

Query: 3751 QAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGS 3810
              A     S + S R   S A+S  P         GLQ               + TT  +
Sbjct: 2660 VEASTRVHSSTGSPRTTLSPASSTSP---------GLQ--------------GESTTFQT 2696

Query: 3811 APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAG 3870
             PA++     P   PSTAT P        E T   +     P     P +    G     
Sbjct: 2697 HPASTHTTPSP---PSTATAPVE------ESTTYHRSPGSTPTT-HFPASSTTSGHSEKS 2746

Query: 3871 VKAGARP---GGTPGAPAGQPGADGESVFSKILPG 3902
                + P   G TP +        GES  S+I PG
Sbjct: 2747 TIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPG 2781



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/228 (24%), Positives = 83/228 (36%), Gaps = 25/228 (10%)

Query: 1374 FSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTE 1433
            FSQ  G+   T++         G  T AS   S     P +T   YG S T     + T+
Sbjct: 161  FSQITGSTVNTSIG--------GNTTSASTPSSS---DPFTTFSDYGVSVTFITGSTATK 209

Query: 1434 DLPQAPSGLAAAGRAAREKPLSASDGEGGTPQ-PSRAYSYFASSSPPLSP-SSPSESPTF 1491
                + +    +G +       +  G  GT   PS + +      P  SP +S S   T 
Sbjct: 210  HFLDSSTN---SGHSEESTVSHSGPGATGTTLFPSHSATSVFVGEPKTSPITSASMETTA 266

Query: 1492 SPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPS-TPRLVWQES 1550
             PG       +E ST   S   + D   SP   T S +  + T +  RP  T  + + +S
Sbjct: 267  LPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSEKSTTSHSRPGPTHTIAFPDS 326

Query: 1551 SQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTT 1598
            +        T+   +   T       ST    SP  T P++ G   TT
Sbjct: 327  T--------TMPGVSQESTASHSIPGSTDTTLSPGTTTPSSLGPESTT 366



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 183/934 (19%), Positives = 280/934 (29%), Gaps = 178/934 (19%)

Query: 3026 TTPAGQ---FVDFPATAAAPATPSGPTA--------FQQPRFQPPAPQYSAGSG--GPTQ 3072
            TT  G+   F  +P++      PSG T+        +       P   +SA S   G ++
Sbjct: 412  TTHEGEPTTFQSWPSSKDTSPAPSGTTSAFVKLSTTYHSSPSSTPTTHFSASSTTLGHSE 471

Query: 3073 NGFPAHQAPTYPGPSTYPAPAFPPG-----ASYPAEPGLPNQQAFRPTGHYAGQTPMP-- 3125
               P H +P     +  PA +   G      +Y   PG      F  +   +G +     
Sbjct: 472  ESTPVHSSPVATATTPPPARSATSGHVEESTAYHRSPGSTQTMHFPESSTTSGHSEESAT 531

Query: 3126 ---TTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSG 3182
               +T  T    P+ + A       +SL   E    T++    S  +   S  S+ S+S 
Sbjct: 532  FHGSTTHTKSSTPSTTAALAHTSYHSSLGSTET---THFR--DSSTISGRSEESKASHSS 586

Query: 3183 P--AVSSGYEQGKVPEV------PRAGDRGSVSQSPAP---TYPSDSHYTSLEQNVPRNY 3231
            P    ++    G  P V      P     GS+  +  P   T P  S  ++   + PR+ 
Sbjct: 587  PDAMATTVLPAGSTPSVLVGDSTPSPISSGSMETTALPGSTTKPGLSEKSTTFYSSPRSP 646

Query: 3232 VMIDDISELTKDSTSTAPDSQRLEPLG------PGSSGRPG--KEPGEPGVLDGPTLPCC 3283
                  + +T    S    +    P        PGS+  PG  +E        GPT    
Sbjct: 647  DTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPGLSQESTASHSSPGPT---- 702

Query: 3284 YARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKH 3343
                +      S      G    +  S      T    D+    G  +E   P     + 
Sbjct: 703  ----DTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTASGL-LEASMPVHSSTRS 757

Query: 3344 PSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRK 3403
            P  +L+PA  ++++ +          + F     +KD         PP  +S+ V     
Sbjct: 758  PHTTLSPAGSTTRQGES---------TTFHSWPSSKDTRP-----APPTTTSAFVE---- 799

Query: 3404 FQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWG 3463
                 ++G   ++         ++   VE+   Y  S  S     +     +S      G
Sbjct: 800  -PSTTSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTS------G 852

Query: 3464 KGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPP 3523
            +G E                S  S  H+    P  + A  EE          P      P
Sbjct: 853  RGEESTT-------------SHSSTTHTISSAPSTTSALVEE----------PTSYHSSP 889

Query: 3524 GGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDW 3583
            G      F  S +     E   +   +H+ +   G I+  +    S      LG+  T  
Sbjct: 890  GSTATTHFPDSSTTSGRSE---ESTASHSSQDATGTIVLPARSTTS----VLLGESTTS- 941

Query: 3584 FDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAK 3643
               P  + S       G   +    +R     ++H     P   L P      G      
Sbjct: 942  ---PISSGSMETTALPGSTTTPGLSERST---TFHSSPRSPATTLSPASTTSSG----VS 991

Query: 3644 EHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSA 3703
            E       R    HT   P           L RH    HS P S            P+S 
Sbjct: 992  EESTTSRSRPGSTHTTAFPDSTTTP----GLSRHSTTSHSSPGSTDTTL------LPAST 1041

Query: 3704 EYSQPSRASSAYHHASDS-----KKGSRQA----------HSGPAALQSKAEPQAQPQLQ 3748
              S PS+ S+  H +S S       GS  A          HS P +  +   P +     
Sbjct: 1042 TTSGPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTS-S 1100

Query: 3749 GRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTR 3808
            G   A     S + S R   S A+S  P  Q +       P     T +       P + 
Sbjct: 1101 GIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPS-------PPST 1153

Query: 3809 GSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGP 3868
             +AP          PG ST T   PA    +  +  S     +P                
Sbjct: 1154 ATAPVEESTTYHRSPG-STPTTHFPASSTTSGHSEKSTIFHSSPDAS------------- 1199

Query: 3869 AGVKAGARPGGTPGAPAGQPGADGESVFSKILPG 3902
                     G TP +        GES  S+I PG
Sbjct: 1200 ---------GTTPSSAHSTTSGRGESTTSRISPG 1224



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 60/284 (21%), Positives = 81/284 (28%), Gaps = 29/284 (10%)

Query: 3616 SYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLG 3675
            ++H     P   L P      G      E     H R    HT   P           L 
Sbjct: 3608 TFHSSPRSPATTLSPASTTSSG----VSEESTTSHSRPGSTHTTAFPDSTTTP----GLS 3659

Query: 3676 RHEARPHSQPSSA-----PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSK----KGSR 3726
            RH    HS P S      PA          S+  +S      +A    S +     + S 
Sbjct: 3660 RHSTTSHSSPGSTDTTLLPASTTTSGSSQESTTSHSSSGSTDTALSPGSTTALSFGQEST 3719

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
              HS P +  +   P +     G   A     S + S R   S A+S  P  Q +     
Sbjct: 3720 TFHSSPGSTHTTLFPDSTTS-SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQ 3778

Query: 3787 LQP--------PQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPR 3838
              P        P    T    +  +   + GS P    PA     G S  +    + P  
Sbjct: 3779 THPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 3838

Query: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPG 3882
            +  T  S   A +   GR         PG   +        TPG
Sbjct: 3839 SGTTPSS---AHSTTSGRGESTTSRISPGSTEITTLPGSTTTPG 3879



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 153/837 (18%), Positives = 252/837 (30%), Gaps = 93/837 (11%)

Query: 3036 PATAAAPATPSGPTAFQ-QPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAF 3094
            PA++ +P      TAFQ  P      P   + +  P +     H++P     + +PA + 
Sbjct: 1122 PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 1181

Query: 3095 PPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLE 3154
              G S  +     +  A   T   A  T     +ST   +   S      P  T+   L 
Sbjct: 1182 TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 1241

Query: 3155 QKVPTNYEVIASPVVPMSSA---------PSETSYSGPAVSSGYEQGKVPEVPRAGDRGS 3205
            +   T Y    SP   +S A          S TS S P  +           P   +  +
Sbjct: 1242 EASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEEST 1301

Query: 3206 VSQSPA-----PTYPSDSHYTSLEQNVPRNY---VMIDDISELTKDSTSTA-PDSQRLEP 3256
               S +      T    S  TS+    P  +         +  T+DST++   +     P
Sbjct: 1302 TVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPASTHTTLFTEDSTTSGLTEESTAFP 1361

Query: 3257 LGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPAS 3316
              P S+     + G P  L    L      GEE +   S       G   +  S  R  +
Sbjct: 1362 GSPAST-----QTGLPATLTTADL------GEESTTFPS-----SSGSTGTKLSPARSTT 1405

Query: 3317 THYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIE 3376
            +   G+S            P  + P     +  P + ++         + +K + F    
Sbjct: 1406 SGLVGEST-----------PSRLSPSSTETTTLPGSPTT-------PSLSEKSTTFYTSP 1447

Query: 3377 EAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRI 3436
             + D     A+  P   +SS VS                 +         S++       
Sbjct: 1448 RSPD-----ATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSS 1502

Query: 3437 YGGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVE-------RLQKAGPKPSSLSMA 3489
             G +  + +P + +   L     +      + E   +         ++ + P  SS    
Sbjct: 1503 QGSTEATLSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSL 1562

Query: 3490 HSRVRPPMRSQASEEESPVSPLGRPRPAG-GPLPPGGDTCPQFCSS--HSMPDVQEHVKD 3546
            H+ + P   + A  +E   +    P  +   P PPG    P   S+  HS P        
Sbjct: 1563 HTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHF 1622

Query: 3547 GPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSS 3606
               +    R E      S    + +  +      +    +P  +           A+  S
Sbjct: 1623 SASSTTLGRSEESTTVHSSPGATGTALFPTRSATSVLVGEPTTSPISSGSTE-TTALPGS 1681

Query: 3607 SQKRGPARHSYHDYDEP--PEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGR 3664
            +   G +  S   Y  P  P+  L P      G      E     H R    HT   PG 
Sbjct: 1682 TTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSG----VSEESTTSHSRPGSTHTTAFPGS 1737

Query: 3665 RAAKPHARDLGRHEARPHSQPSS-----APAMPKKGQPGYPSSAEYSQPSRASSAY---- 3715
                     + +     HS P S     +P        G  S+  +S P    +      
Sbjct: 1738 TTMP----GVSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDN 1793

Query: 3716 HHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ 3775
              AS   + S   HS   +  +   P      QG ++        S  +   P    S  
Sbjct: 1794 TTASGLLEASTPVHSSTGSPHTTLSPAGSTTRQG-ESTTFQSWPSSKDTMPAPPTTTSAF 1852

Query: 3776 PQTQQQQQGLGLQPPQQ--ALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATG 3830
             +      G     P    + +   L +  + TT  S+P A+  A  P P  ST +G
Sbjct: 1853 VELSTTSHGSPSSTPTTHFSASSTTLGRSEESTTVHSSPVAT--ATTPSPARSTTSG 1907



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 32/140 (22%), Positives = 50/140 (35%), Gaps = 1/140 (0%)

Query: 3036 PATAAAPATPSGPTAFQ-QPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAF 3094
            PA++ +P      TAFQ  P      P   + +  P +     H++P     + +PA + 
Sbjct: 2205 PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 2264

Query: 3095 PPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLE 3154
              G S  +     +  A   T   A  T     +ST   +   S      P  T+   L 
Sbjct: 2265 TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 2324

Query: 3155 QKVPTNYEVIASPVVPMSSA 3174
            +   T Y    SP   +S A
Sbjct: 2325 EASTTFYSSPRSPTTTLSPA 2344



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 32/140 (22%), Positives = 50/140 (35%), Gaps = 1/140 (0%)

Query: 3036 PATAAAPATPSGPTAFQ-QPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAF 3094
            PA++ +P      TAFQ  P      P   + +  P +     H++P     + +PA + 
Sbjct: 3762 PASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVEESTTYHRSPGSTPTTHFPASST 3821

Query: 3095 PPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLE 3154
              G S  +     +  A   T   A  T     +ST   +   S      P  T+   L 
Sbjct: 3822 TSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGESTTSRISPGSTEITTLPGSTTTPGLS 3881

Query: 3155 QKVPTNYEVIASPVVPMSSA 3174
            +   T Y    SP   +S A
Sbjct: 3882 EASTTFYSSPRSPTTTLSPA 3901



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 42/212 (19%), Positives = 69/212 (32%), Gaps = 23/212 (10%)

Query: 3697 PGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKA--EPQAQPQLQGRQAAP 3754
            PG   +  + + S AS     +  S   +    S P +  S    EP +     G  A  
Sbjct: 1919 PGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATT 1978

Query: 3755 GPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAA 3814
                S + S R   S A+     + Q   G  + P +   +    +  + P + GS    
Sbjct: 1979 HFPDSSTTSGRSEESTAS----HSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETT 2034

Query: 3815 SQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAG 3874
            + P     PG S             E++     + ++P    +P +  + G       + 
Sbjct: 2035 ALPGSTTTPGLS-------------EKSTTFHSSPRSPATTLSPASTTSSGVSEESTTSH 2081

Query: 3875 ARPGGTPGA----PAGQPGADGESVFSKILPG 3902
            +RPG T           PG    S  S   PG
Sbjct: 2082 SRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPG 2113



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 31/128 (24%), Positives = 49/128 (38%), Gaps = 13/128 (10%)

Query: 3810 SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG--SKGTA-----KAPQQGRAPQAQP 3862
            S  A S   G+P+  P T+   +    P +  T G   K T      ++P +  +P    
Sbjct: 241  SHSATSVFVGEPKTSPITSASMETTALPGSTTTAGLSEKSTTFYSSPRSPDRTLSPARTT 300

Query: 3863 APGPGPAGVKAGARPGGT-----PGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSA 3917
            + G       + +RPG T     P +    PG   ES  S  +PG         T   S+
Sbjct: 301  SSGVSEKSTTSHSRPGPTHTIAFPDSTT-MPGVSQESTASHSIPGSTDTTLSPGTTTPSS 359

Query: 3918 FGKKFSSF 3925
             G + ++F
Sbjct: 360  LGPESTTF 367



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 54/283 (19%), Positives = 94/283 (33%), Gaps = 17/283 (6%)

Query: 3604 SSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG 3663
            S+++   G    ++H      E  L P D    G    A    H   G     HT   P 
Sbjct: 1514 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL-VEASTPTHSSTG---SLHTTLTPA 1569

Query: 3664 RRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK 3723
               +     +    ++ P S  ++         P   S+  +S+PS   + +  AS +  
Sbjct: 1570 SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSASSTTL 1629

Query: 3724 G----SRQAHSGPAALQSKAEP--QAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQ 3777
            G    S   HS P A  +   P   A   L G +    P  S S  +  +P    +    
Sbjct: 1630 GRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETTALPGSTTTAGLS 1688

Query: 3778 TQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
             +        + P   L+ A        T+ G +  ++    +P    +TA       P 
Sbjct: 1689 EKSTTFYSSPRSPDTTLSPA------STTSSGVSEESTTSHSRPGSTHTTAFPGSTTMPG 1742

Query: 3838 RAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
             ++++  S  +  +     +P +  A   GP      + PG T
Sbjct: 1743 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 1785



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 54/283 (19%), Positives = 94/283 (33%), Gaps = 17/283 (6%)

Query: 3604 SSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG 3663
            S+++   G    ++H      E  L P D    G    A    H   G     HT   P 
Sbjct: 4154 STTASSLGQQSTTFHSSPGDTETTLLPDDTITSGL-VEASTPTHSSTG---SLHTTLTPA 4209

Query: 3664 RRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK 3723
               +     +    ++ P S  ++         P   S+  +S+PS   + +  AS +  
Sbjct: 4210 SSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYHSRPSSTPTTHFSASSTTL 4269

Query: 3724 G----SRQAHSGPAALQSKAEP--QAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQ 3777
            G    S   HS P A  +   P   A   L G +    P  S S  +  +P    +    
Sbjct: 4270 GRSEESTTVHSSPGATGTALFPTRSATSVLVG-EPTTSPISSGSTETTALPGSTTTAGLS 4328

Query: 3778 TQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
             +        + P   L+ A        T+ G +  ++    +P    +TA       P 
Sbjct: 4329 EKSTTFYSSPRSPDTTLSPA------STTSSGVSEESTTSHSRPGSMHTTAFPSSTTMPG 4382

Query: 3838 RAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT 3880
             ++++  S  +  +     +P +  A   GP      + PG T
Sbjct: 4383 VSQESTASHSSPGSTDTTLSPGSTTASSLGPESTTFHSSPGST 4425


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 91.3 bits (225), Expect = 2e-17
 Identities = 154/638 (24%), Positives = 212/638 (33%), Gaps = 102/638 (15%)

Query: 47  PAAGAARSTAVPPVPGPG-PGPGPGPGPGSTSRRLDPKEPLGNQRAASPT-PKQ------ 98
           P   A  +T  P +  P  P P     P ST+    PKEP      ++PT PK+      
Sbjct: 197 PTPKAETTTKGPALTTPKEPTPTTPKEPASTT----PKEPTPTTIKSAPTTPKEPAPTTT 252

Query: 99  -ASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYS 157
            ++ TTP   +P  T+   P   +   P  T +    T +S  +    P     PT+P  
Sbjct: 253 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP----APTTP-- 306

Query: 158 VPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNP-NPHLTQVKEWL 216
             + AP       P        +TP +P   T               P  P  T  KE  
Sbjct: 307 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 217 CLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGS 276
                  +      T  P   + ++        A +  K+P     +     P  P P +
Sbjct: 366 PTT---PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 422

Query: 277 RQAETARATSVPGPA-----QAAAPPEVGRVSPQPPQPT---KPSTAEPRPPAGEAPAKS 328
            +         P P          P E    +P+ P PT   KP+   P+ PA   P ++
Sbjct: 423 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 482

Query: 329 ATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP-APSKGTPKIV 387
           A   P  L  T  T E L        A   T    L    PE  T   P  P+  TPK  
Sbjct: 483 APTTPKKL--TPTTPEKLAPTTPEKPAP--TTPEELAPTTPEEPTPTTPEEPAPTTPKAA 538

Query: 388 FNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQA 447
             +  KE             PAP    EP A   P       PK    T+PK G A    
Sbjct: 539 APNTPKE-------------PAPTTPKEP-APTTPKEPAPTTPKETAPTTPK-GTAPTTL 583

Query: 448 ASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEK 507
              A   PK  P  + + P         +K P    T TTC           P P   + 
Sbjct: 584 KEPAPTTPK-KPAPKELAP-------TTTKEP----TSTTCD---------KPAPTTPKG 622

Query: 508 TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGP 567
           T                   PT    P    P   AP    GT+P   K P     P  P
Sbjct: 623 T------------------APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-TPKKP 663

Query: 568 LPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEP-MPKPPPET 626
            P + +P +TK       ++   KP   +     P++ +E     P K  P  P+ PP T
Sbjct: 664 APKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 719

Query: 627 T---PTPATPKVKSGVRRA-EPATPVVKAVPEAPKGGE 660
           T    TP T K  + + ++ + +TP + A P  PK  E
Sbjct: 720 TSEVSTPTTTKEPTTIHKSPDESTPELSAEP-TPKALE 756



 Score = 82.0 bits (201), Expect = 1e-14
 Identities = 146/706 (20%), Positives = 221/706 (31%), Gaps = 104/706 (14%)

Query: 15  PLPPGGAGPGPGPG--PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPG 72
           P P     P P     P P   K P AP      P      +   P  P P     P P 
Sbjct: 262 PAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 320

Query: 73  PGSTSRRLDPKEPLGNQRAASPT---------PKQASATTPGHESPRETRAQGPAGQEAD 123
                    PKEP    +  +PT         PK+ + TTP   +P   +   P   +  
Sbjct: 321 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 380

Query: 124 GPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
            P    +    T +S  + +  P   +T ++P +  + +P  +    P        +TP 
Sbjct: 381 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 440

Query: 184 QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLH 243
           +P   T  +       +    P P  T+           + A      TAP +  +    
Sbjct: 441 KPAPTTPKEPAPTTPKE----PAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPT 493

Query: 244 SPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVS 303
           +P      +P K     P++     P  P P + +     A + P  A    P E     
Sbjct: 494 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPNTPKE----- 545

Query: 304 PQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST 363
           P P  P +P+   P+ PA   P ++A   P G                       T  +T
Sbjct: 546 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG-----------------------TAPTT 582

Query: 364 LMSVQPEADTQGQPAPSKGTPKIVFNDAS----KEAGPKPLGSGP--GPGPAPGAKTEPG 417
           L   +P   T  +PAP +  P       S    K A   P G+ P     PAP    EP 
Sbjct: 583 LK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 640

Query: 418 ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSK 477
                G+ P  L +   TT  K    E    +       T  K     P   A       
Sbjct: 641 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 700

Query: 478 SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTS- 536
           +P      TT +          P P   E          T       +  PT    PT+ 
Sbjct: 701 AP------TTPK---------KPAPTTPE----------TPPPTTSEVSTPTTTKEPTTI 735

Query: 537 -QQPPVGAPHRASGTSP-LKQKGPQGLGQPSGPLPAKASPLST------------KASPL 582
            + P    P  ++  +P   +  P+  G P+   PA   P  T            + +P 
Sbjct: 736 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 795

Query: 583 PSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT---PTPATPKVKSGV 639
            + A+P+     A+   KT  S     T   T        P + T    T   PKV +  
Sbjct: 796 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT-T 854

Query: 640 RRAEPATPVVKAVPEA--PKGGEAEDLVGKPYSQDASRSPQSLSDT 683
           ++    T ++    E   PK          P  Q  +++P+  + T
Sbjct: 855 KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 900



 Score = 80.1 bits (196), Expect = 4e-14
 Identities = 128/576 (22%), Positives = 196/576 (34%), Gaps = 65/576 (11%)

Query: 132 DSRTQRSGRSPSVSP---DRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFN 188
           D++  R+ + P+  P   D   +           P  S+T      TS   +T    N  
Sbjct: 68  DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 127

Query: 189 TCTQCHNKVCNQCGFNPNPHLT-QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPAL 247
                ++    +     N   T + KE    N Q         T+A  ++S ++  +  L
Sbjct: 128 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 187

Query: 248 SPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPP 307
           +P      +P  K +   ++GP    P      T +  +   P +    P   + +P  P
Sbjct: 188 APTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT--PTTIKSAPTTP 244

Query: 308 QPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSV 367
           +   P+T +  P   + PA + T  PA    T +     T K     A   T+++     
Sbjct: 245 KEPAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKE---PAPTTTKSAPTTPK 299

Query: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPG---PAPGAKTEPGARMGPGS 424
           +P   T  +PAP+  TPK       KE  P      P P    PAP    EP A   P  
Sbjct: 300 EPAPTTPKKPAPT--TPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEP-APTAPKK 355

Query: 425 GPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNT 484
                PK    T+PK       A +       T PKE A      A       +P    +
Sbjct: 356 PAPTTPKEPAPTTPKE-----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 410

Query: 485 CTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAP 544
             T   +        P+P              TK     +  EP P  P   ++P    P
Sbjct: 411 APTTPKE--------PSP------------TTTKEPAPTTPKEPAPTTP---KKPAPTTP 447

Query: 545 HRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTK--ASPLPSKASPQAKPLRASEPSKTP 602
              + T+P K+  P    +P+   P + +P + K  A   P K +P      A    + P
Sbjct: 448 KEPAPTTP-KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 506

Query: 603 SSVQEKKTRVPTKAEPMPKPPPETTPT--------------PATPKVKSGVRRAEPA-TP 647
           +    ++    T  EP P  P E  PT              P TPK  +     EPA T 
Sbjct: 507 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 566

Query: 648 VVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDT 683
             +  P  PKG     L     +     +P+ L+ T
Sbjct: 567 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 146/715 (20%), Positives = 239/715 (33%), Gaps = 89/715 (12%)

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQR 1066
            D+S ++  ++  + +   A+  +  P LP   D+S+E  L   +E   E ++     +Q 
Sbjct: 103  DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 162

Query: 1067 IRSTARKTRRDKEELRAQRRRERSKTPPSNL--SPIEDASPTEE------LRQAAEMEEL 1118
                  KT   KE    ++   +   P S +   P   A  T +       ++       
Sbjct: 163  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 222

Query: 1119 HRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSG 1178
              +S +   P+P+    A      P+      +    PT     +PT T   + TTP   
Sbjct: 223  EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPTTTKEPAPTTPKEP 278

Query: 1179 RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG 1238
             P  + E A      K+     ++      + P   P+ P  P      E   TT +E  
Sbjct: 279  APTTTKEPA--PTTTKSAPTTPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPA 334

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYM 1298
               +  A  TP        ++   T+                     KE     A +   
Sbjct: 335  PTTKEPAPTTPKEPAPTAPKKPAPTTP--------------------KEP----APTTPK 370

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            +P        +P T+P + A   + S PT++             T      T       +
Sbjct: 371  EPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 429

Query: 1359 SPASPSSASKEIGMPFSQGPGTPA-TTAVAPCPAGLPR-GYMTPASPAGSERSPSPSSTA 1416
            +P  P+  + +   P +  P  PA TT   P P    +    TP  PA +    +  +T 
Sbjct: 430  TPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 487

Query: 1417 HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASS 1476
                 +PTT    + T     AP+          E+P   +  E     P  A       
Sbjct: 488  KKL--TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 545

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA----PASDMPRSPG----APT--- 1525
              P +P  P+ +    P    P+ TA  + +  +P     PA   P+ P     APT   
Sbjct: 546  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 605

Query: 1526 ---------PSPMVAQGTQ----------TPHRPS--TPRLVWQESSQE-APFMVITLAS 1563
                     P+P   +GT           TP  P+  TP+     + +E AP      A 
Sbjct: 606  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 665

Query: 1564 DASSQTRMVHASASTSPLCSPT---ETQPTTHGY-SQTTPPSVSQLPPEPPGPPGFPRVP 1619
               + T     +++TS   +PT   ET PTT    + TTP   +   PE P P       
Sbjct: 666  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 725

Query: 1620 SAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKP 1674
                  P  ++      + + S   +S+ P    +E  P+ PG        A KP
Sbjct: 726  PTTTKEPTTIH-----KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 775



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 148/707 (20%), Positives = 228/707 (32%), Gaps = 83/707 (11%)

Query: 952  PDPSLDREPELEME-SLTGSPEDRSRGEHSSTL--PASTPSYTSGTSPTSLSSLEEDS-- 1006
            P PSL    +   E SLT + E     + ++T     ST      TS     S+E+ S  
Sbjct: 126  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 185

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLL-----PTIEDSSEEEELREEEELLREQEKMRE 1061
            D +P+ +     AK   KA   + GP L     PT     E      +E      +    
Sbjct: 186  DLAPTSKVL---AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 242

Query: 1062 VEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRS 1121
              ++   +T +      +E      +E + T P   +P     P     ++A       +
Sbjct: 243  TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 302

Query: 1122 SCSEYSPSPSLDSEA------EALDGGPSRLYKSGSE-------YNLPTFMSLYSPTETP 1168
              +   P+P+   E       E     P     +  E          PT     +PT   
Sbjct: 303  PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 362

Query: 1169 SGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE 1228
              + TTP    P  + E +       A    +          P    S PT P+     E
Sbjct: 363  EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-----E 417

Query: 1229 YQDTTDREYGQAA-QPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKE 1287
               TT +E      +  A  TP        +E   T+    +    ++         K+ 
Sbjct: 418  PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEP 474

Query: 1288 KQFLNAESAYMDPMK------QNGGPLTPG----TSPTQLAAPVSFSTPTSSDSSGGRVI 1337
                  E+A   P K      +   P TP     T+P +LA P +   PT +        
Sbjct: 475  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPEEPTPTTPEEPAPT 533

Query: 1338 PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGY 1397
                   +  KE         +P +P   +     P    P TP  TA        P   
Sbjct: 534  TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKEPAPT-- 589

Query: 1398 MTPASPAGSERSPS----PSSTAHSY-------GHSPTTANYGSQT---EDLPQAPSGLA 1443
             TP  PA  E +P+    P+ST           G +PTT    + T   E  P  P G A
Sbjct: 590  -TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 648

Query: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
                     P +  +     P P+           P +   P+ + +  P    P+ TA 
Sbjct: 649  ---------PTTLKE-----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 694

Query: 1504 FSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLA 1562
             + + P+P  P    P +P  P P+        T   P+T      ES+ E        A
Sbjct: 695  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754

Query: 1563 SDASSQTRMVHAS---ASTSPLCSPTETQPTTHGYSQTTPPSVSQLP 1606
             + S +   V  +   A+T P  + T    TT    +TTP + +  P
Sbjct: 755  LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 801



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 145/693 (20%), Positives = 217/693 (31%), Gaps = 111/693 (16%)

Query: 1309 TPGTSPTQ-----------LAAPVSF--STPTSSDSSGGRVIPDVRVTQHFAKETQDPLK 1355
            TP TS TQ            A P++   S P +SD+S    +   + T    KET    K
Sbjct: 101  TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 160

Query: 1356 LHSSPASP--SSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPA-GSERSPSP 1412
              S+      +SA +   +  +       T+ V   P   P+   T   PA  + + P+P
Sbjct: 161  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT--PKAETTTKGPALTTPKEPTP 218

Query: 1413 SSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSY 1472
                       TT    + T      P+ + +A    +E            P P+     
Sbjct: 219  -----------TTPKEPASTTPKEPTPTTIKSAPTTPKE------------PAPT----- 250

Query: 1473 FASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQ 1532
              + S P +P  P+ + T  P    P+  A  +T+ P+P      P +P  P P+     
Sbjct: 251  -TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 309

Query: 1533 GTQTPHR--PSTPRLVWQESSQE-APFMVITLASDASSQTRMVHASASTSPL-CSPTETQ 1588
               TP    P+TP+     + +E AP    T    A +  +    +A   P   +P E  
Sbjct: 310  APTTPKEPAPTTPKEPTPTTPKEPAP----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 365

Query: 1589 PTT-HGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGAD-GPLALYGWGALPAENISLCRIS 1646
            PTT    + TT    S   P+ P P      P+   +  P         P E        
Sbjct: 366  PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 425

Query: 1647 SVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGR 1706
              P T + EP P TP        T  +P P    +     T           A  P   +
Sbjct: 426  PAPTTPK-EPAPTTPKKPAP--TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPK 480

Query: 1707 QSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGG 1766
            ++    P  +     E     T    + T    +     ++P                  
Sbjct: 481  ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT----------------- 523

Query: 1767 SPVCLAQVKQVEQAVQTAPYRSGP----RGRPREAKFARYNLPNQVAPLARRDVL-ITQM 1821
                       E+   T P  + P       P   K      P + AP   ++    T  
Sbjct: 524  -------PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 576

Query: 1822 GTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPE 1881
            GTA +   +P P       P    P   +        KP        +GTA T     P+
Sbjct: 577  GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT---PKGTAPTT----PK 629

Query: 1882 EPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPF 1941
            EPA     T   P             P G++ T    PAP+ P+K       P  +  P 
Sbjct: 630  EPA---PTTPKEPAP---------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 677

Query: 1942 YGPRD-PEPPEPPTYRAQGVVGPGPHEEQRPYP 1973
                D P P  P          P P   ++P P
Sbjct: 678  STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 710



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 138/639 (21%), Positives = 209/639 (32%), Gaps = 122/639 (19%)

Query: 1347 AKETQDPLKLHSSPASPSSA--------------SKEIGMPFSQGPGTP----ATTAVAP 1388
            AKETQ   K  +   +P+S                  +  P    P TP    +TT   P
Sbjct: 173  AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 232

Query: 1389 CPAGLPRGYMTPASPAGSE--------RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
             P  +     TP  PA +         + P+P++T      +PTT    + T     AP+
Sbjct: 233  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP---APTTPKEPAPTTTKEPAPT 289

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
               +A    +E P   +  +     P            P +P  P+ + T  P    P+ 
Sbjct: 290  TTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-TKEPAPTTPKE 347

Query: 1501 TAEFSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
             A  + + P+P  P    P +P  P P+      T     P+TP+       + AP    
Sbjct: 348  PAPTAPKKPAPTTPKEPAPTTPKEPAPT------TTKEPSPTTPK-------EPAP---- 390

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQP-TTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
            T    A + T+    + + S   +P E  P TT   + TTP   +   P+ P P   P+ 
Sbjct: 391  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKE 449

Query: 1619 PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPII 1678
            P+               P E          P T + EP P TP          + PT   
Sbjct: 450  PAP------------TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPT--- 493

Query: 1679 LTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMAS 1738
             T + +  T+    A      L P    + T   P                   +   A+
Sbjct: 494  -TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--------------EEPAPTTPKAA 538

Query: 1739 SVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAK 1798
            +    ++  P    +P  +         +P   A     E A  T P  + P      A 
Sbjct: 539  APNTPKEPAPTTPKEPAPT---------TPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP 588

Query: 1799 FA-RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGA 1857
               +   P ++AP   ++   T          KP P    G  P   TP E      P  
Sbjct: 589  TTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAP--TTPKE------PAP 633

Query: 1858 RKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTF 1917
              P        +GTA T      +EPA     T  +P  +    ++      G + T + 
Sbjct: 634  TTPKEPAPTTPKGTAPTTL----KEPA---PTTPKKPAPK----ELAPTTTKGPTSTTSD 682

Query: 1918 HPAPSVPEKSMADAAP--PGQSSSPFYGPRDPEPPEPPT 1954
             PAP+ P K  A   P  P  ++     P  PE P P T
Sbjct: 683  KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 720



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 50/201 (24%), Positives = 73/201 (36%), Gaps = 26/201 (12%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSG----GPTQNGFPAHQAPTYPGPST--YPAPAF 3094
            AP TP  PT        P  P+ +A +      PT    PA   P  P P+T    AP  
Sbjct: 515  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 574

Query: 3095 PPGAS-------YPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQ 3147
            P G +        P  P  P  +   PT      T  PT+ +   P P         P+ 
Sbjct: 575  PKGTAPTTLKEPAPTTPKKPAPKELAPT-----TTKEPTSTTCDKPAPTT-------PKG 622

Query: 3148 TSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVS 3207
            T+    ++  PT  +  A P  P  +AP+      P         ++      G   + S
Sbjct: 623  TAPTTPKEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 681

Query: 3208 QSPAPTYPSDSHYTSLEQNVP 3228
              PAPT P ++  T+ ++  P
Sbjct: 682  DKPAPTTPKETAPTTPKEPAP 702



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 15/216 (6%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +K+ S      PA   +
Sbjct: 339  EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-----TTTKEPSPTTPKEPAPTTT 393

Query: 3738 KAEPQA--QPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALT 3795
            K+ P    +P     ++AP   +  SP++ + P+    ++P     ++     P + A T
Sbjct: 394  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 453

Query: 3796 QAR-----LQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA 3849
              +       ++  PTT +  AP   +      P   T T P+   P   E+   +    
Sbjct: 454  TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 513

Query: 3850 KAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
             AP     P       P P   KA A    TP  PA
Sbjct: 514  LAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPA 547



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 82/377 (21%), Positives = 129/377 (34%), Gaps = 39/377 (10%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            TT A +      T+A    P+     +      P P+    + GP     P    PT P 
Sbjct: 170  TTSAKETQSIEKTSAKDLAPTSKVLAK------PTPKAETTTKGPALTT-PKEPTPTTPK 222

Query: 3086 PSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT----PMPTTQSTLFPVPADSRAP 3141
                  P  P   +  + P  P + A  PT   +  T    P PTT  T  P P   + P
Sbjct: 223  EPASTTPKEPTPTTIKSAPTTPKEPA--PTTTKSAPTTPKEPAPTT--TKEPAPTTPKEP 278

Query: 3142 LQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAG 3201
                 +       +  PT  +  A P  P   AP  T+   PA ++  E    P  P+  
Sbjct: 279  APTTTKEPAPTTTKSAPTTPKEPA-PTTPKKPAP--TTPKEPAPTTPKE--PTPTTPK-- 331

Query: 3202 DRGSVSQSPAPTYPSDSHYTSLEQNVPRN------YVMIDDISELTKDSTSTAPDSQRLE 3255
            +    ++ PAPT P +   T+ ++  P            +     TK+ + T P  +   
Sbjct: 332  EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPA 389

Query: 3256 PLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPA 3315
            P    S+    KEP        PT P      +E S   + +P        +  +  +PA
Sbjct: 390  PTTTKSAPTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPA 443

Query: 3316 ST--HYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFS 3373
             T       +  +  A      P P  PK P+ +  P   +    K       +K++  +
Sbjct: 444  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTT 502

Query: 3374 PIEEAKDVESDLASYPP 3390
            P + A     +LA   P
Sbjct: 503  PEKPAPTTPEELAPTTP 519



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 130/638 (20%), Positives = 213/638 (33%), Gaps = 90/638 (14%)

Query: 952  PDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPS 1011
            P P+  +EP     + T  P   +  E + T   S P+ T   +PT+  S    +   PS
Sbjct: 364  PAPTTPKEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT-TPKEPS 419

Query: 1012 RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTA 1071
                 E A               PT          ++      ++      ++    +T 
Sbjct: 420  PTTTKEPA---------------PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 464

Query: 1072 RKTRRDKEELRAQRRRERSKTPPSNLSPI--EDASPTEELRQAAEM-EELHRSSCSEYSP 1128
            +      +E      +E + T P  L+P   E  +PT   + A    EEL  ++  E +P
Sbjct: 465  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 524

Query: 1129 S----PSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSA 1184
            +    P+  +   A    P     +  +   PT     +PT     + TTP    P    
Sbjct: 525  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 584

Query: 1185 EEAYEEMMRKA--ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE------ 1236
            E A     + A  EL      +          P+ P G       E   TT +E      
Sbjct: 585  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 644

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESA 1296
             G A     E  P +      +E+  T+    +   +++ D       K+       E A
Sbjct: 645  KGTAPTTLKEPAPTTPKKPAPKELAPTT---TKGPTSTTSDKPAPTTPKETAPTTPKEPA 701

Query: 1297 YMDPMKQNGGPLTPGTSP---TQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
               P K    P TP T P   ++++ P +   PT+   S     PD    +  A+ T  P
Sbjct: 702  PTTPKKP--APTTPETPPPTTSEVSTPTTTKEPTTIHKS-----PDESTPELSAEPT--P 752

Query: 1354 LKLHSSPASPSSASKEIGMPFSQGPG---------------------TPATTAVAPCPAG 1392
              L +SP       KE G+P ++ P                      TP TT  AP    
Sbjct: 753  KALENSP-------KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP---- 801

Query: 1393 LPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREK 1452
                 MT  +   +E++     TA +   + TT    +  +      + LA      ++ 
Sbjct: 802  ----KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 857

Query: 1453 PLSA---SDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG-KMGPRATAEFSTQT 1508
              +    +  E       RA +  A++  P  P+   + PT +   K  PR     +T T
Sbjct: 858  ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 917

Query: 1509 PSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
            P     S MP        +  + Q T  P++    +LV
Sbjct: 918  PRKM-TSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLV 954



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 51/242 (21%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSS-AEYSQPSRASSAYH 3716
            T +EP   A K  A    +  A P +    AP   K+  P  P   A  +  S  ++   
Sbjct: 344  TPKEPAPTAPKKPAPTTPKEPA-PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQP 3776
             A  + K +      P+   +K      P    ++ AP   +  +P++ + P+    ++P
Sbjct: 403  PAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP 458

Query: 3777 QTQQQQQGLGLQPPQQALTQARLQQQSQPTT----RGSAPAASQPAGKPQPGPSTA---- 3828
                 ++     P + A T  +   ++ PTT      + P    P    +P P+T     
Sbjct: 459  APTTTKKPAPTTPKEPAPTTPK---ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 515

Query: 3829 -TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ 3887
             T P+   P   E+   +   A AP   + P       P P   K  A       AP   
Sbjct: 516  PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 575

Query: 3888 PG 3889
             G
Sbjct: 576  KG 577



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 8/211 (3%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+   P  P      T  E  PSP    +  P   +        P+  T ++A  
Sbjct: 356  PAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 413

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPM-IAPRV 2251
                   T      P T +  +   P           +      P  + T+ P    P+ 
Sbjct: 414  TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 473

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T     P   +  +  + P    P    KPA    P    P+ PE P     EEP 
Sbjct: 474  PAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPA 531

Query: 2312 PTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            PTT  AA       PAP      K PA   P
Sbjct: 532  PTTPKAAAPNTPKEPAPTT---PKEPAPTTP 559



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/230 (24%), Positives = 73/230 (31%), Gaps = 23/230 (10%)

Query: 2132 GPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAAD 2191
            GP L+ P+   P  P    + T  E  P+    A   P     T  +   P+T    A  
Sbjct: 207  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPT 265

Query: 2192 GMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV 2251
                    TP       T +PA             P  +      P T     P   P+ 
Sbjct: 266  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKE 324

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T   + PAP+    A + P    P    KPA         P+ P+ P     +EP 
Sbjct: 325  PTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPA---------PTTPKEPAPTTPKEPA 373

Query: 2312 PTTT----PAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
            PTTT    P   KE      PAP   +  P        +   S P   KE
Sbjct: 374  PTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 417



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 44/238 (18%), Positives = 78/238 (32%), Gaps = 16/238 (6%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            T +EP     K  A    +  A P +   +AP  PKK  P  P     + P + +     
Sbjct: 454  TPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 512

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ-- 3775
                        + P    +   P+A      ++ AP   +  +P++ + P+    ++  
Sbjct: 513  ELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 571

Query: 3776 PQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRG------------SAPAASQPAGKPQP 3823
            P T +      L+ P     +    ++  PTT              + P  + P    +P
Sbjct: 572  PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 631

Query: 3824 GPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTP 3881
             P+T   P P  P     T   +     P++    +  P    GP    +      TP
Sbjct: 632  APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 19/235 (8%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+ L P  P     PT PE  P+P       P A      ++  P+T    A   
Sbjct: 506  PAPTTPEELAPTTPEE-PTPTTPE-EPAPTT-----PKAAAPNTPKEPAPTTPKEPAPTT 558

Query: 2193 MIYSTINTP--IAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPR 2250
                   TP   A T P  T P ++  P               T     + T     AP 
Sbjct: 559  PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618

Query: 2251 VPLG--PTGLYRYPAPS--RFPIASSVPPAEGPVYLGKPAAAK----APGAGGPSRPEMP 2302
             P G  PT   + PAP+  + P A + P    P  L +PA       AP    P+  + P
Sbjct: 619  TPKGTAPT-TPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 676

Query: 2303 VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
                 ++P PTT           PAP       P     P   +  +S P   KE
Sbjct: 677  TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 731



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 3026 TTPAGQFVDFPATAA-------APATPSG--PTAFQQPRF---QPPAPQYSAGSGGPTQN 3073
            TTP G     P   A       AP TP G  PT  ++P     + PAP+  A    PT  
Sbjct: 618  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA----PTTT 673

Query: 3074 GFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFP 3133
              P       P P+T P    P     PA P  P + A  PT     +TP PTT     P
Sbjct: 674  KGPTSTTSDKPAPTT-PKETAPTTPKEPA-PTTPKKPA--PT---TPETPPPTTSEVSTP 726

Query: 3134 VPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV---VPMSSAPSET 3178
                    + K    S  +L  + PT   +  SP    VP +  P+ T
Sbjct: 727  TTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAAT 773



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 28/216 (12%)

Query: 2138 PQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTA---VRQLLPSTATVRAADGMI 2194
            P    P  P     PT P+  P+P    +  P   +GTA   +++  P+T    A   + 
Sbjct: 546  PAPTTPKEPA----PTTPK-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600

Query: 2195 YSTINTPIAATL--PITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
             +T   P + T   P  T P        +            T    T+ T +   AP  P
Sbjct: 601  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660

Query: 2253 LGPTGLYRYPAPSRFPIA--SSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEP 2310
              P      P  ++ P +  S  P    P    K  A   P    P+ P+ P     E P
Sbjct: 661  KKPAPKELAPTTTKGPTSTTSDKPAPTTP----KETAPTTPKEPAPTTPKKPAPTTPETP 716

Query: 2311 LPTT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
             PTT    TP   KE        P    K P ++ P
Sbjct: 717  PPTTSEVSTPTTTKE--------PTTIHKSPDESTP 744



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 34/178 (19%), Positives = 62/178 (34%), Gaps = 11/178 (6%)

Query: 3687 SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQ 3746
            SAP  PK+  P    SA  +    A +       +K+ +      PA   +K     +P 
Sbjct: 239  SAPTTPKEPAPTTTKSAPTTPKEPAPTT------TKEPAPTTPKEPAPTTTK-----EPA 287

Query: 3747 LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT 3806
                ++AP   +  +P++ + P+    ++P     ++     P + A T       +   
Sbjct: 288  PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 347

Query: 3807 TRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAP 3864
               +AP    P    +P P+T   P P        T   +      +       +PAP
Sbjct: 348  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 405



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 45/236 (19%), Positives = 71/236 (30%), Gaps = 30/236 (12%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +KK +      PA    
Sbjct: 425  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKKPAPTTPKEPAPTTP 479

Query: 3738 KAEPQAQPQ------------LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGL 3785
            K      P+                + AP   +  +P++ + P+     +P     +   
Sbjct: 480  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 539

Query: 3786 GLQPPQQALTQARLQQQSQPTTRG-SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +    + P     + P  + P       P+T   P P  P +      
Sbjct: 540  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599

Query: 3845 SKGTAKAP------------QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            +  T K P             +G AP     P P      A   P GT      +P
Sbjct: 600  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 655



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 37/121 (30%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 2239 TSLTRVPMIAPRVP--LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP 2296
            T+ T    + P  P  L PT   + PAP+     +   P E      +  A   P A  P
Sbjct: 482  TAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 540

Query: 2297 SRPEMPVGAAREEPLPTT----TPAAIKEAA------GAPA----PAPLAGQKP-PADAA 2341
            + P+ P     +EP PTT     P   KE A       AP     PAP   +KP P + A
Sbjct: 541  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600

Query: 2342 P 2342
            P
Sbjct: 601  P 601



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 48/244 (19%), Positives = 81/244 (33%), Gaps = 31/244 (12%)

Query: 3657 HTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYH 3716
            +T +EP     K  A    +  A P +   +AP  PK   P        + P + +    
Sbjct: 541  NTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 599

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQG----RQAAPGPQQSQSPSSRQIPSGAA 3772
              + +K+ +      PA    K      P+       ++ AP   +  +P++ + P+   
Sbjct: 600  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 659

Query: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQ 3832
             ++P  ++      L P       +    +  PTT    P  + P    +P P+T   P 
Sbjct: 660  PKKPAPKE------LAPTTTKGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPKKPA 709

Query: 3833 PAGPPRAEQTNGSKGTA----------KAPQQGRAP-QAQPAP-----GPGPAGVKAGAR 3876
            P  P     T     T           K+P +      A+P P      P   GV     
Sbjct: 710  PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 769

Query: 3877 PGGT 3880
            P  T
Sbjct: 770  PAAT 773



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 52/214 (24%), Positives = 70/214 (32%), Gaps = 17/214 (7%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  +AP+   P  P     PT P+  P+P    +  P     T  ++  P+T        
Sbjct: 348  PAPTAPKKPAPTTPKEPA-PTTPK-EPAPTTTKEPSP-----TTPKEPAPTTTKSAPTTT 400

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
               +   T  A T P    P +   P        P  +      P T     P   P+ P
Sbjct: 401  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPT-TPKEP 458

Query: 2253 LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLP 2312
               T   + PAP+     +   P E      K      P    P+ PE P     EE  P
Sbjct: 459  APTTT--KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 516

Query: 2313 TT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            TT    TP   +E   AP     A    P + AP
Sbjct: 517  TTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 548



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 41/212 (19%), Positives = 78/212 (36%), Gaps = 20/212 (9%)

Query: 3682 HSQPSSAP----AMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK----GSRQAHSGPA 3733
            H++ S++P    A P   +P  P +++ S+ +  +       ++K+      + +  G  
Sbjct: 109  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 168

Query: 3734 ALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSR-----QIPSGAASRQPQTQQQQQGLGLQ 3788
               S  E Q+  +   +  AP  +    P+ +     + P+    ++P     ++     
Sbjct: 169  KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 228

Query: 3789 PPQQALTQAR----LQQQSQPTTRGSAPAA-SQPAGKPQPGPSTATGPQPAGPPRAEQTN 3843
            P +   T  +      ++  PTT  SAP    +PA      P+  T  +PA  P   +  
Sbjct: 229  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEP 286

Query: 3844 GSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
                T  AP   + P       P P   K  A
Sbjct: 287  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 318



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 46/210 (21%), Positives = 65/210 (30%), Gaps = 8/210 (3%)

Query: 2152 PTFPEGHPSPGNLAQYGPAAGQG--TAVRQLLPSTATVRAADGMIYSTINTPIAATLPIT 2209
            PT P+  P+P    +  P   +   T  ++  P+T    A          TP   T    
Sbjct: 272  PTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 330

Query: 2210 TQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPI 2269
             +PA   +         P  +      P T     P   P+ P   T     P   + P 
Sbjct: 331  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPTTPKEPA 389

Query: 2270 ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPA 2329
             ++   A  P    +PA      A  P+ P+ P     +EP PTT           PAP 
Sbjct: 390  PTTTKSA--PTTTKEPAPTTTKSA--PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 445

Query: 2330 PLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
                  P     P   +     P   KE A
Sbjct: 446  TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 475



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 37/209 (17%), Positives = 69/209 (33%), Gaps = 6/209 (2%)

Query: 3667 AKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            +K  A+   + E        + P  P    P  P+S    +P+  +      +  +    
Sbjct: 191  SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 250

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS-RQPQTQQQQQGL 3785
               S P   +  A    +         P P  ++ P+     S   + ++P     ++  
Sbjct: 251  TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 310

Query: 3786 GLQPPQQALTQARLQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +   +  PTT +  AP   +PA      P+  T P+   P   ++   
Sbjct: 311  PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEPAP 366

Query: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKA 3873
            +     AP   + P       P P   K+
Sbjct: 367  TTPKEPAPTTTKEPSPTTPKEPAPTTTKS 395


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 91.3 bits (225), Expect = 2e-17
 Identities = 154/638 (24%), Positives = 212/638 (33%), Gaps = 102/638 (15%)

Query: 47  PAAGAARSTAVPPVPGPG-PGPGPGPGPGSTSRRLDPKEPLGNQRAASPT-PKQ------ 98
           P   A  +T  P +  P  P P     P ST+    PKEP      ++PT PK+      
Sbjct: 238 PTPKAETTTKGPALTTPKEPTPTTPKEPASTT----PKEPTPTTIKSAPTTPKEPAPTTT 293

Query: 99  -ASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYS 157
            ++ TTP   +P  T+   P   +   P  T +    T +S  +    P     PT+P  
Sbjct: 294 KSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEP----APTTP-- 347

Query: 158 VPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNP-NPHLTQVKEWL 216
             + AP       P        +TP +P   T               P  P  T  KE  
Sbjct: 348 -KKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 217 CLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGS 276
                  +      T  P   + ++        A +  K+P     +     P  P P +
Sbjct: 407 PTT---PKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT 463

Query: 277 RQAETARATSVPGPA-----QAAAPPEVGRVSPQPPQPT---KPSTAEPRPPAGEAPAKS 328
            +         P P          P E    +P+ P PT   KP+   P+ PA   P ++
Sbjct: 464 TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKET 523

Query: 329 ATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP-APSKGTPKIV 387
           A   P  L  T  T E L        A   T    L    PE  T   P  P+  TPK  
Sbjct: 524 APTTPKKL--TPTTPEKLAPTTPEKPAP--TTPEELAPTTPEEPTPTTPEEPAPTTPKAA 579

Query: 388 FNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQA 447
             +  KE             PAP    EP A   P       PK    T+PK G A    
Sbjct: 580 APNTPKE-------------PAPTTPKEP-APTTPKEPAPTTPKETAPTTPK-GTAPTTL 624

Query: 448 ASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEK 507
              A   PK  P  + + P         +K P    T TTC           P P   + 
Sbjct: 625 KEPAPTTPK-KPAPKELAP-------TTTKEP----TSTTCD---------KPAPTTPKG 663

Query: 508 TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGP 567
           T                   PT    P    P   AP    GT+P   K P     P  P
Sbjct: 664 T------------------APTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPT-TPKKP 704

Query: 568 LPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEP-MPKPPPET 626
            P + +P +TK       ++   KP   +     P++ +E     P K  P  P+ PP T
Sbjct: 705 APKELAPTTTKG----PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPT 760

Query: 627 T---PTPATPKVKSGVRRA-EPATPVVKAVPEAPKGGE 660
           T    TP T K  + + ++ + +TP + A P  PK  E
Sbjct: 761 TSEVSTPTTTKEPTTIHKSPDESTPELSAEP-TPKALE 797



 Score = 82.0 bits (201), Expect = 1e-14
 Identities = 146/706 (20%), Positives = 221/706 (31%), Gaps = 104/706 (14%)

Query: 15  PLPPGGAGPGPGPG--PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPG 72
           P P     P P     P P   K P AP      P      +   P  P P     P P 
Sbjct: 303 PAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 361

Query: 73  PGSTSRRLDPKEPLGNQRAASPT---------PKQASATTPGHESPRETRAQGPAGQEAD 123
                    PKEP    +  +PT         PK+ + TTP   +P   +   P   +  
Sbjct: 362 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 421

Query: 124 GPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
            P    +    T +S  + +  P   +T ++P +  + +P  +    P        +TP 
Sbjct: 422 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 481

Query: 184 QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLH 243
           +P   T  +       +    P P  T+           + A      TAP +  +    
Sbjct: 482 KPAPTTPKEPAPTTPKE----PAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPT 534

Query: 244 SPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVS 303
           +P      +P K     P++     P  P P + +     A + P  A    P E     
Sbjct: 535 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPNTPKE----- 586

Query: 304 PQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST 363
           P P  P +P+   P+ PA   P ++A   P G                       T  +T
Sbjct: 587 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG-----------------------TAPTT 623

Query: 364 LMSVQPEADTQGQPAPSKGTPKIVFNDAS----KEAGPKPLGSGP--GPGPAPGAKTEPG 417
           L   +P   T  +PAP +  P       S    K A   P G+ P     PAP    EP 
Sbjct: 624 LK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 681

Query: 418 ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSK 477
                G+ P  L +   TT  K    E    +       T  K     P   A       
Sbjct: 682 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 741

Query: 478 SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTS- 536
           +P      TT +          P P   E          T       +  PT    PT+ 
Sbjct: 742 AP------TTPK---------KPAPTTPE----------TPPPTTSEVSTPTTTKEPTTI 776

Query: 537 -QQPPVGAPHRASGTSP-LKQKGPQGLGQPSGPLPAKASPLST------------KASPL 582
            + P    P  ++  +P   +  P+  G P+   PA   P  T            + +P 
Sbjct: 777 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 836

Query: 583 PSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT---PTPATPKVKSGV 639
            + A+P+     A+   KT  S     T   T        P + T    T   PKV +  
Sbjct: 837 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT-T 895

Query: 640 RRAEPATPVVKAVPEA--PKGGEAEDLVGKPYSQDASRSPQSLSDT 683
           ++    T ++    E   PK          P  Q  +++P+  + T
Sbjct: 896 KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 941



 Score = 80.1 bits (196), Expect = 4e-14
 Identities = 128/576 (22%), Positives = 196/576 (34%), Gaps = 65/576 (11%)

Query: 132 DSRTQRSGRSPSVSP---DRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFN 188
           D++  R+ + P+  P   D   +           P  S+T      TS   +T    N  
Sbjct: 109 DNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPR 168

Query: 189 TCTQCHNKVCNQCGFNPNPHLT-QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPAL 247
                ++    +     N   T + KE    N Q         T+A  ++S ++  +  L
Sbjct: 169 PSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDL 228

Query: 248 SPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPP 307
           +P      +P  K +   ++GP    P      T +  +   P +    P   + +P  P
Sbjct: 229 APTSKVLAKPTPKAETT-TKGPALTTPKEPTPTTPKEPASTTPKEPT--PTTIKSAPTTP 285

Query: 308 QPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSV 367
           +   P+T +  P   + PA + T  PA    T +     T K     A   T+++     
Sbjct: 286 KEPAPTTTKSAPTTPKEPAPTTTKEPAP--TTPKEPAPTTTKE---PAPTTTKSAPTTPK 340

Query: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPG---PAPGAKTEPGARMGPGS 424
           +P   T  +PAP+  TPK       KE  P      P P    PAP    EP A   P  
Sbjct: 341 EPAPTTPKKPAPT--TPKEPAPTTPKEPTPTT-PKEPAPTTKEPAPTTPKEP-APTAPKK 396

Query: 425 GPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNT 484
                PK    T+PK       A +       T PKE A      A       +P    +
Sbjct: 397 PAPTTPKEPAPTTPKE-----PAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKS 451

Query: 485 CTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAP 544
             T   +        P+P              TK     +  EP P  P   ++P    P
Sbjct: 452 APTTPKE--------PSP------------TTTKEPAPTTPKEPAPTTP---KKPAPTTP 488

Query: 545 HRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTK--ASPLPSKASPQAKPLRASEPSKTP 602
              + T+P K+  P    +P+   P + +P + K  A   P K +P      A    + P
Sbjct: 489 KEPAPTTP-KEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKP 547

Query: 603 SSVQEKKTRVPTKAEPMPKPPPETTPT--------------PATPKVKSGVRRAEPA-TP 647
           +    ++    T  EP P  P E  PT              P TPK  +     EPA T 
Sbjct: 548 APTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT 607

Query: 648 VVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDT 683
             +  P  PKG     L     +     +P+ L+ T
Sbjct: 608 PKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 146/715 (20%), Positives = 239/715 (33%), Gaps = 89/715 (12%)

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQR 1066
            D+S ++  ++  + +   A+  +  P LP   D+S+E  L   +E   E ++     +Q 
Sbjct: 144  DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 203

Query: 1067 IRSTARKTRRDKEELRAQRRRERSKTPPSNL--SPIEDASPTEE------LRQAAEMEEL 1118
                  KT   KE    ++   +   P S +   P   A  T +       ++       
Sbjct: 204  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 263

Query: 1119 HRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSG 1178
              +S +   P+P+    A      P+      +    PT     +PT T   + TTP   
Sbjct: 264  EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPTTTKEPAPTTPKEP 319

Query: 1179 RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG 1238
             P  + E A      K+     ++      + P   P+ P  P      E   TT +E  
Sbjct: 320  APTTTKEPA--PTTTKSAPTTPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPA 375

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYM 1298
               +  A  TP        ++   T+                     KE     A +   
Sbjct: 376  PTTKEPAPTTPKEPAPTAPKKPAPTTP--------------------KEP----APTTPK 411

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            +P        +P T+P + A   + S PT++             T      T       +
Sbjct: 412  EPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 470

Query: 1359 SPASPSSASKEIGMPFSQGPGTPA-TTAVAPCPAGLPR-GYMTPASPAGSERSPSPSSTA 1416
            +P  P+  + +   P +  P  PA TT   P P    +    TP  PA +    +  +T 
Sbjct: 471  TPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 528

Query: 1417 HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASS 1476
                 +PTT    + T     AP+          E+P   +  E     P  A       
Sbjct: 529  KKL--TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 586

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA----PASDMPRSPG----APT--- 1525
              P +P  P+ +    P    P+ TA  + +  +P     PA   P+ P     APT   
Sbjct: 587  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 646

Query: 1526 ---------PSPMVAQGTQ----------TPHRPS--TPRLVWQESSQE-APFMVITLAS 1563
                     P+P   +GT           TP  P+  TP+     + +E AP      A 
Sbjct: 647  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 706

Query: 1564 DASSQTRMVHASASTSPLCSPT---ETQPTTHGY-SQTTPPSVSQLPPEPPGPPGFPRVP 1619
               + T     +++TS   +PT   ET PTT    + TTP   +   PE P P       
Sbjct: 707  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 766

Query: 1620 SAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKP 1674
                  P  ++      + + S   +S+ P    +E  P+ PG        A KP
Sbjct: 767  PTTTKEPTTIH-----KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 816



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 148/707 (20%), Positives = 228/707 (32%), Gaps = 83/707 (11%)

Query: 952  PDPSLDREPELEME-SLTGSPEDRSRGEHSSTL--PASTPSYTSGTSPTSLSSLEEDS-- 1006
            P PSL    +   E SLT + E     + ++T     ST      TS     S+E+ S  
Sbjct: 167  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 226

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLL-----PTIEDSSEEEELREEEELLREQEKMRE 1061
            D +P+ +     AK   KA   + GP L     PT     E      +E      +    
Sbjct: 227  DLAPTSKVL---AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 283

Query: 1062 VEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRS 1121
              ++   +T +      +E      +E + T P   +P     P     ++A       +
Sbjct: 284  TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 343

Query: 1122 SCSEYSPSPSLDSEA------EALDGGPSRLYKSGSE-------YNLPTFMSLYSPTETP 1168
              +   P+P+   E       E     P     +  E          PT     +PT   
Sbjct: 344  PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 403

Query: 1169 SGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE 1228
              + TTP    P  + E +       A    +          P    S PT P+     E
Sbjct: 404  EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-----E 458

Query: 1229 YQDTTDREYGQAA-QPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKE 1287
               TT +E      +  A  TP        +E   T+    +    ++         K+ 
Sbjct: 459  PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEP 515

Query: 1288 KQFLNAESAYMDPMK------QNGGPLTPG----TSPTQLAAPVSFSTPTSSDSSGGRVI 1337
                  E+A   P K      +   P TP     T+P +LA P +   PT +        
Sbjct: 516  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPEEPTPTTPEEPAPT 574

Query: 1338 PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGY 1397
                   +  KE         +P +P   +     P    P TP  TA        P   
Sbjct: 575  TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKEPAPT-- 630

Query: 1398 MTPASPAGSERSPS----PSSTAHSY-------GHSPTTANYGSQT---EDLPQAPSGLA 1443
             TP  PA  E +P+    P+ST           G +PTT    + T   E  P  P G A
Sbjct: 631  -TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 689

Query: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
                     P +  +     P P+           P +   P+ + +  P    P+ TA 
Sbjct: 690  ---------PTTLKE-----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 735

Query: 1504 FSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLA 1562
             + + P+P  P    P +P  P P+        T   P+T      ES+ E        A
Sbjct: 736  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 795

Query: 1563 SDASSQTRMVHAS---ASTSPLCSPTETQPTTHGYSQTTPPSVSQLP 1606
             + S +   V  +   A+T P  + T    TT    +TTP + +  P
Sbjct: 796  LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 842



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 145/693 (20%), Positives = 217/693 (31%), Gaps = 111/693 (16%)

Query: 1309 TPGTSPTQ-----------LAAPVSF--STPTSSDSSGGRVIPDVRVTQHFAKETQDPLK 1355
            TP TS TQ            A P++   S P +SD+S    +   + T    KET    K
Sbjct: 142  TPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNK 201

Query: 1356 LHSSPASP--SSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPA-GSERSPSP 1412
              S+      +SA +   +  +       T+ V   P   P+   T   PA  + + P+P
Sbjct: 202  QTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPT--PKAETTTKGPALTTPKEPTP 259

Query: 1413 SSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSY 1472
                       TT    + T      P+ + +A    +E            P P+     
Sbjct: 260  -----------TTPKEPASTTPKEPTPTTIKSAPTTPKE------------PAPT----- 291

Query: 1473 FASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQ 1532
              + S P +P  P+ + T  P    P+  A  +T+ P+P      P +P  P P+     
Sbjct: 292  -TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKP 350

Query: 1533 GTQTPHR--PSTPRLVWQESSQE-APFMVITLASDASSQTRMVHASASTSPL-CSPTETQ 1588
               TP    P+TP+     + +E AP    T    A +  +    +A   P   +P E  
Sbjct: 351  APTTPKEPAPTTPKEPTPTTPKEPAP----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPA 406

Query: 1589 PTT-HGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGAD-GPLALYGWGALPAENISLCRIS 1646
            PTT    + TT    S   P+ P P      P+   +  P         P E        
Sbjct: 407  PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKE 466

Query: 1647 SVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGR 1706
              P T + EP P TP        T  +P P    +     T           A  P   +
Sbjct: 467  PAPTTPK-EPAPTTPKKPAP--TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPK 521

Query: 1707 QSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGG 1766
            ++    P  +     E     T    + T    +     ++P                  
Sbjct: 522  ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPT----------------- 564

Query: 1767 SPVCLAQVKQVEQAVQTAPYRSGP----RGRPREAKFARYNLPNQVAPLARRDVL-ITQM 1821
                       E+   T P  + P       P   K      P + AP   ++    T  
Sbjct: 565  -------PTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPK 617

Query: 1822 GTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPE 1881
            GTA +   +P P       P    P   +        KP        +GTA T     P+
Sbjct: 618  GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTT---PKGTAPTT----PK 670

Query: 1882 EPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPF 1941
            EPA     T   P             P G++ T    PAP+ P+K       P  +  P 
Sbjct: 671  EPA---PTTPKEPAP---------TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPT 718

Query: 1942 YGPRD-PEPPEPPTYRAQGVVGPGPHEEQRPYP 1973
                D P P  P          P P   ++P P
Sbjct: 719  STTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 751



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 138/639 (21%), Positives = 209/639 (32%), Gaps = 122/639 (19%)

Query: 1347 AKETQDPLKLHSSPASPSSA--------------SKEIGMPFSQGPGTP----ATTAVAP 1388
            AKETQ   K  +   +P+S                  +  P    P TP    +TT   P
Sbjct: 214  AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 273

Query: 1389 CPAGLPRGYMTPASPAGSE--------RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
             P  +     TP  PA +         + P+P++T      +PTT    + T     AP+
Sbjct: 274  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP---APTTPKEPAPTTTKEPAPT 330

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
               +A    +E P   +  +     P            P +P  P+ + T  P    P+ 
Sbjct: 331  TTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-TKEPAPTTPKE 388

Query: 1501 TAEFSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
             A  + + P+P  P    P +P  P P+      T     P+TP+       + AP    
Sbjct: 389  PAPTAPKKPAPTTPKEPAPTTPKEPAPT------TTKEPSPTTPK-------EPAP---- 431

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQP-TTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
            T    A + T+    + + S   +P E  P TT   + TTP   +   P+ P P   P+ 
Sbjct: 432  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKE 490

Query: 1619 PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPII 1678
            P+               P E          P T + EP P TP          + PT   
Sbjct: 491  PAP------------TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPT--- 534

Query: 1679 LTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMAS 1738
             T + +  T+    A      L P    + T   P                   +   A+
Sbjct: 535  -TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--------------EEPAPTTPKAA 579

Query: 1739 SVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAK 1798
            +    ++  P    +P  +         +P   A     E A  T P  + P      A 
Sbjct: 580  APNTPKEPAPTTPKEPAPT---------TPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP 629

Query: 1799 FA-RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGA 1857
               +   P ++AP   ++   T          KP P    G  P   TP E      P  
Sbjct: 630  TTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAP--TTPKE------PAP 674

Query: 1858 RKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTF 1917
              P        +GTA T      +EPA     T  +P  +    ++      G + T + 
Sbjct: 675  TTPKEPAPTTPKGTAPTTL----KEPA---PTTPKKPAPK----ELAPTTTKGPTSTTSD 723

Query: 1918 HPAPSVPEKSMADAAP--PGQSSSPFYGPRDPEPPEPPT 1954
             PAP+ P K  A   P  P  ++     P  PE P P T
Sbjct: 724  KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 761



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 50/201 (24%), Positives = 73/201 (36%), Gaps = 26/201 (12%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSG----GPTQNGFPAHQAPTYPGPST--YPAPAF 3094
            AP TP  PT        P  P+ +A +      PT    PA   P  P P+T    AP  
Sbjct: 556  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 615

Query: 3095 PPGAS-------YPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQ 3147
            P G +        P  P  P  +   PT      T  PT+ +   P P         P+ 
Sbjct: 616  PKGTAPTTLKEPAPTTPKKPAPKELAPT-----TTKEPTSTTCDKPAPTT-------PKG 663

Query: 3148 TSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVS 3207
            T+    ++  PT  +  A P  P  +AP+      P         ++      G   + S
Sbjct: 664  TAPTTPKEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 722

Query: 3208 QSPAPTYPSDSHYTSLEQNVP 3228
              PAPT P ++  T+ ++  P
Sbjct: 723  DKPAPTTPKETAPTTPKEPAP 743



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 15/216 (6%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +K+ S      PA   +
Sbjct: 380  EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-----TTTKEPSPTTPKEPAPTTT 434

Query: 3738 KAEPQA--QPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALT 3795
            K+ P    +P     ++AP   +  SP++ + P+    ++P     ++     P + A T
Sbjct: 435  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 494

Query: 3796 QAR-----LQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA 3849
              +       ++  PTT +  AP   +      P   T T P+   P   E+   +    
Sbjct: 495  TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 554

Query: 3850 KAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
             AP     P       P P   KA A    TP  PA
Sbjct: 555  LAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPA 588



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 82/377 (21%), Positives = 129/377 (34%), Gaps = 39/377 (10%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            TT A +      T+A    P+     +      P P+    + GP     P    PT P 
Sbjct: 211  TTSAKETQSIEKTSAKDLAPTSKVLAK------PTPKAETTTKGPALTT-PKEPTPTTPK 263

Query: 3086 PSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT----PMPTTQSTLFPVPADSRAP 3141
                  P  P   +  + P  P + A  PT   +  T    P PTT  T  P P   + P
Sbjct: 264  EPASTTPKEPTPTTIKSAPTTPKEPA--PTTTKSAPTTPKEPAPTT--TKEPAPTTPKEP 319

Query: 3142 LQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAG 3201
                 +       +  PT  +  A P  P   AP  T+   PA ++  E    P  P+  
Sbjct: 320  APTTTKEPAPTTTKSAPTTPKEPA-PTTPKKPAP--TTPKEPAPTTPKE--PTPTTPK-- 372

Query: 3202 DRGSVSQSPAPTYPSDSHYTSLEQNVPRN------YVMIDDISELTKDSTSTAPDSQRLE 3255
            +    ++ PAPT P +   T+ ++  P            +     TK+ + T P  +   
Sbjct: 373  EPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPA 430

Query: 3256 PLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPA 3315
            P    S+    KEP        PT P      +E S   + +P        +  +  +PA
Sbjct: 431  PTTTKSAPTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPA 484

Query: 3316 ST--HYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFS 3373
             T       +  +  A      P P  PK P+ +  P   +    K       +K++  +
Sbjct: 485  PTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTT 543

Query: 3374 PIEEAKDVESDLASYPP 3390
            P + A     +LA   P
Sbjct: 544  PEKPAPTTPEELAPTTP 560



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 130/638 (20%), Positives = 213/638 (33%), Gaps = 90/638 (14%)

Query: 952  PDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPS 1011
            P P+  +EP     + T  P   +  E + T   S P+ T   +PT+  S    +   PS
Sbjct: 405  PAPTTPKEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT-TPKEPS 460

Query: 1012 RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTA 1071
                 E A               PT          ++      ++      ++    +T 
Sbjct: 461  PTTTKEPA---------------PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 505

Query: 1072 RKTRRDKEELRAQRRRERSKTPPSNLSPI--EDASPTEELRQAAEM-EELHRSSCSEYSP 1128
            +      +E      +E + T P  L+P   E  +PT   + A    EEL  ++  E +P
Sbjct: 506  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 565

Query: 1129 S----PSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSA 1184
            +    P+  +   A    P     +  +   PT     +PT     + TTP    P    
Sbjct: 566  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 625

Query: 1185 EEAYEEMMRKA--ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE------ 1236
            E A     + A  EL      +          P+ P G       E   TT +E      
Sbjct: 626  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 685

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESA 1296
             G A     E  P +      +E+  T+    +   +++ D       K+       E A
Sbjct: 686  KGTAPTTLKEPAPTTPKKPAPKELAPTT---TKGPTSTTSDKPAPTTPKETAPTTPKEPA 742

Query: 1297 YMDPMKQNGGPLTPGTSP---TQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
               P K    P TP T P   ++++ P +   PT+   S     PD    +  A+ T  P
Sbjct: 743  PTTPKKP--APTTPETPPPTTSEVSTPTTTKEPTTIHKS-----PDESTPELSAEPT--P 793

Query: 1354 LKLHSSPASPSSASKEIGMPFSQGPG---------------------TPATTAVAPCPAG 1392
              L +SP       KE G+P ++ P                      TP TT  AP    
Sbjct: 794  KALENSP-------KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP---- 842

Query: 1393 LPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREK 1452
                 MT  +   +E++     TA +   + TT    +  +      + LA      ++ 
Sbjct: 843  ----KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 898

Query: 1453 PLSA---SDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG-KMGPRATAEFSTQT 1508
              +    +  E       RA +  A++  P  P+   + PT +   K  PR     +T T
Sbjct: 899  ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 958

Query: 1509 PSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
            P     S MP        +  + Q T  P++    +LV
Sbjct: 959  PRKM-TSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLV 995



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 51/242 (21%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSS-AEYSQPSRASSAYH 3716
            T +EP   A K  A    +  A P +    AP   K+  P  P   A  +  S  ++   
Sbjct: 385  TPKEPAPTAPKKPAPTTPKEPA-PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQP 3776
             A  + K +      P+   +K      P    ++ AP   +  +P++ + P+    ++P
Sbjct: 444  PAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP 499

Query: 3777 QTQQQQQGLGLQPPQQALTQARLQQQSQPTT----RGSAPAASQPAGKPQPGPSTA---- 3828
                 ++     P + A T  +   ++ PTT      + P    P    +P P+T     
Sbjct: 500  APTTTKKPAPTTPKEPAPTTPK---ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 556

Query: 3829 -TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ 3887
             T P+   P   E+   +   A AP   + P       P P   K  A       AP   
Sbjct: 557  PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 616

Query: 3888 PG 3889
             G
Sbjct: 617  KG 618



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 8/211 (3%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+   P  P      T  E  PSP    +  P   +        P+  T ++A  
Sbjct: 397  PAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 454

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPM-IAPRV 2251
                   T      P T +  +   P           +      P  + T+ P    P+ 
Sbjct: 455  TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 514

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T     P   +  +  + P    P    KPA    P    P+ PE P     EEP 
Sbjct: 515  PAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPA 572

Query: 2312 PTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            PTT  AA       PAP      K PA   P
Sbjct: 573  PTTPKAAAPNTPKEPAPTT---PKEPAPTTP 600



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/230 (24%), Positives = 73/230 (31%), Gaps = 23/230 (10%)

Query: 2132 GPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAAD 2191
            GP L+ P+   P  P    + T  E  P+    A   P     T  +   P+T    A  
Sbjct: 248  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPT 306

Query: 2192 GMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV 2251
                    TP       T +PA             P  +      P T     P   P+ 
Sbjct: 307  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKE 365

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T   + PAP+    A + P    P    KPA         P+ P+ P     +EP 
Sbjct: 366  PTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPA---------PTTPKEPAPTTPKEPA 414

Query: 2312 PTTT----PAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
            PTTT    P   KE      PAP   +  P        +   S P   KE
Sbjct: 415  PTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 458



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 44/238 (18%), Positives = 78/238 (32%), Gaps = 16/238 (6%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            T +EP     K  A    +  A P +   +AP  PKK  P  P     + P + +     
Sbjct: 495  TPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 553

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ-- 3775
                        + P    +   P+A      ++ AP   +  +P++ + P+    ++  
Sbjct: 554  ELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 612

Query: 3776 PQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRG------------SAPAASQPAGKPQP 3823
            P T +      L+ P     +    ++  PTT              + P  + P    +P
Sbjct: 613  PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 672

Query: 3824 GPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTP 3881
             P+T   P P  P     T   +     P++    +  P    GP    +      TP
Sbjct: 673  APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 19/235 (8%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+ L P  P     PT PE  P+P       P A      ++  P+T    A   
Sbjct: 547  PAPTTPEELAPTTPEE-PTPTTPE-EPAPTT-----PKAAAPNTPKEPAPTTPKEPAPTT 599

Query: 2193 MIYSTINTP--IAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPR 2250
                   TP   A T P  T P ++  P               T     + T     AP 
Sbjct: 600  PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659

Query: 2251 VPLG--PTGLYRYPAPS--RFPIASSVPPAEGPVYLGKPAAAK----APGAGGPSRPEMP 2302
             P G  PT   + PAP+  + P A + P    P  L +PA       AP    P+  + P
Sbjct: 660  TPKGTAPT-TPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 717

Query: 2303 VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
                 ++P PTT           PAP       P     P   +  +S P   KE
Sbjct: 718  TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 772



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 3026 TTPAGQFVDFPATAA-------APATPSG--PTAFQQPRF---QPPAPQYSAGSGGPTQN 3073
            TTP G     P   A       AP TP G  PT  ++P     + PAP+  A    PT  
Sbjct: 659  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA----PTTT 714

Query: 3074 GFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFP 3133
              P       P P+T P    P     PA P  P + A  PT     +TP PTT     P
Sbjct: 715  KGPTSTTSDKPAPTT-PKETAPTTPKEPA-PTTPKKPA--PT---TPETPPPTTSEVSTP 767

Query: 3134 VPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV---VPMSSAPSET 3178
                    + K    S  +L  + PT   +  SP    VP +  P+ T
Sbjct: 768  TTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAAT 814



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 28/216 (12%)

Query: 2138 PQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTA---VRQLLPSTATVRAADGMI 2194
            P    P  P     PT P+  P+P    +  P   +GTA   +++  P+T    A   + 
Sbjct: 587  PAPTTPKEPA----PTTPK-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641

Query: 2195 YSTINTPIAATL--PITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
             +T   P + T   P  T P        +            T    T+ T +   AP  P
Sbjct: 642  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701

Query: 2253 LGPTGLYRYPAPSRFPIA--SSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEP 2310
              P      P  ++ P +  S  P    P    K  A   P    P+ P+ P     E P
Sbjct: 702  KKPAPKELAPTTTKGPTSTTSDKPAPTTP----KETAPTTPKEPAPTTPKKPAPTTPETP 757

Query: 2311 LPTT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
             PTT    TP   KE        P    K P ++ P
Sbjct: 758  PPTTSEVSTPTTTKE--------PTTIHKSPDESTP 785



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 34/178 (19%), Positives = 62/178 (34%), Gaps = 11/178 (6%)

Query: 3687 SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQ 3746
            SAP  PK+  P    SA  +    A +       +K+ +      PA   +K     +P 
Sbjct: 280  SAPTTPKEPAPTTTKSAPTTPKEPAPTT------TKEPAPTTPKEPAPTTTK-----EPA 328

Query: 3747 LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT 3806
                ++AP   +  +P++ + P+    ++P     ++     P + A T       +   
Sbjct: 329  PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 388

Query: 3807 TRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAP 3864
               +AP    P    +P P+T   P P        T   +      +       +PAP
Sbjct: 389  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 446



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 45/236 (19%), Positives = 71/236 (30%), Gaps = 30/236 (12%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +KK +      PA    
Sbjct: 466  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKKPAPTTPKEPAPTTP 520

Query: 3738 KAEPQAQPQ------------LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGL 3785
            K      P+                + AP   +  +P++ + P+     +P     +   
Sbjct: 521  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 580

Query: 3786 GLQPPQQALTQARLQQQSQPTTRG-SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +    + P     + P  + P       P+T   P P  P +      
Sbjct: 581  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640

Query: 3845 SKGTAKAP------------QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            +  T K P             +G AP     P P      A   P GT      +P
Sbjct: 641  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 696



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 37/121 (30%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 2239 TSLTRVPMIAPRVP--LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP 2296
            T+ T    + P  P  L PT   + PAP+     +   P E      +  A   P A  P
Sbjct: 523  TAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 581

Query: 2297 SRPEMPVGAAREEPLPTT----TPAAIKEAA------GAPA----PAPLAGQKP-PADAA 2341
            + P+ P     +EP PTT     P   KE A       AP     PAP   +KP P + A
Sbjct: 582  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641

Query: 2342 P 2342
            P
Sbjct: 642  P 642



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 48/244 (19%), Positives = 81/244 (33%), Gaps = 31/244 (12%)

Query: 3657 HTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYH 3716
            +T +EP     K  A    +  A P +   +AP  PK   P        + P + +    
Sbjct: 582  NTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 640

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQG----RQAAPGPQQSQSPSSRQIPSGAA 3772
              + +K+ +      PA    K      P+       ++ AP   +  +P++ + P+   
Sbjct: 641  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 700

Query: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQ 3832
             ++P  ++      L P       +    +  PTT    P  + P    +P P+T   P 
Sbjct: 701  PKKPAPKE------LAPTTTKGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPKKPA 750

Query: 3833 PAGPPRAEQTNGSKGTA----------KAPQQGRAP-QAQPAP-----GPGPAGVKAGAR 3876
            P  P     T     T           K+P +      A+P P      P   GV     
Sbjct: 751  PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 810

Query: 3877 PGGT 3880
            P  T
Sbjct: 811  PAAT 814



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 52/214 (24%), Positives = 70/214 (32%), Gaps = 17/214 (7%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  +AP+   P  P     PT P+  P+P    +  P     T  ++  P+T        
Sbjct: 389  PAPTAPKKPAPTTPKEPA-PTTPK-EPAPTTTKEPSP-----TTPKEPAPTTTKSAPTTT 441

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
               +   T  A T P    P +   P        P  +      P T     P   P+ P
Sbjct: 442  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPT-TPKEP 499

Query: 2253 LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLP 2312
               T   + PAP+     +   P E      K      P    P+ PE P     EE  P
Sbjct: 500  APTTT--KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 557

Query: 2313 TT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            TT    TP   +E   AP     A    P + AP
Sbjct: 558  TTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 589



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 41/212 (19%), Positives = 78/212 (36%), Gaps = 20/212 (9%)

Query: 3682 HSQPSSAP----AMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK----GSRQAHSGPA 3733
            H++ S++P    A P   +P  P +++ S+ +  +       ++K+      + +  G  
Sbjct: 150  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 209

Query: 3734 ALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSR-----QIPSGAASRQPQTQQQQQGLGLQ 3788
               S  E Q+  +   +  AP  +    P+ +     + P+    ++P     ++     
Sbjct: 210  KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 269

Query: 3789 PPQQALTQAR----LQQQSQPTTRGSAPAA-SQPAGKPQPGPSTATGPQPAGPPRAEQTN 3843
            P +   T  +      ++  PTT  SAP    +PA      P+  T  +PA  P   +  
Sbjct: 270  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEP 327

Query: 3844 GSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
                T  AP   + P       P P   K  A
Sbjct: 328  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 359



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 46/210 (21%), Positives = 65/210 (30%), Gaps = 8/210 (3%)

Query: 2152 PTFPEGHPSPGNLAQYGPAAGQG--TAVRQLLPSTATVRAADGMIYSTINTPIAATLPIT 2209
            PT P+  P+P    +  P   +   T  ++  P+T    A          TP   T    
Sbjct: 313  PTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 371

Query: 2210 TQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPI 2269
             +PA   +         P  +      P T     P   P+ P   T     P   + P 
Sbjct: 372  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPTTPKEPA 430

Query: 2270 ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPA 2329
             ++   A  P    +PA      A  P+ P+ P     +EP PTT           PAP 
Sbjct: 431  PTTTKSA--PTTTKEPAPTTTKSA--PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 486

Query: 2330 PLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
                  P     P   +     P   KE A
Sbjct: 487  TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 516



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 37/209 (17%), Positives = 69/209 (33%), Gaps = 6/209 (2%)

Query: 3667 AKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            +K  A+   + E        + P  P    P  P+S    +P+  +      +  +    
Sbjct: 232  SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 291

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS-RQPQTQQQQQGL 3785
               S P   +  A    +         P P  ++ P+     S   + ++P     ++  
Sbjct: 292  TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 351

Query: 3786 GLQPPQQALTQARLQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +   +  PTT +  AP   +PA      P+  T P+   P   ++   
Sbjct: 352  PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEPAP 407

Query: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKA 3873
            +     AP   + P       P P   K+
Sbjct: 408  TTPKEPAPTTTKEPSPTTPKEPAPTTTKS 436


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 143/674 (21%), Positives = 235/674 (34%), Gaps = 73/674 (10%)

Query: 36  PPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPT 95
           P S P+     P +GA+++        P P     P    T + ++ +E +  + + S  
Sbjct: 69  PTSPPSSKKAPPPSGASQTIKSTTKRSPKP-----PNKKKTKKVIESEE-ITEEHSVSEN 122

Query: 96  PKQASATTPGHESP--RETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSP---DRGS 150
            + +S+++    S   R+ ++   +    +  ++    D++  R+ + P+  P   D   
Sbjct: 123 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 182

Query: 151 TPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLT 210
           +           P  S+T      TS   +T    N       ++    +     N   T
Sbjct: 183 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 242

Query: 211 -QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGP 269
            + KE    N Q         T+A  ++S ++  +  L+P      +P  K +   ++GP
Sbjct: 243 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT-TKGP 301

Query: 270 GGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA 329
               P      T +  +   P +    P   + +P  P+   P+T +  P   + PA + 
Sbjct: 302 ALTTPKEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 359

Query: 330 TAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFN 389
           T  PA    T +     T K     A   T+++     +P   T  +PAP+  TPK    
Sbjct: 360 TKEPAP--TTPKEPAPTTTKE---PAPTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAP 412

Query: 390 DASKEAGPKPLGSGPGPG---PAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQ 446
              KE  P      P P    PAP    EP A   P       PK    T+PK       
Sbjct: 413 TTPKEPTPTT-PKEPAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKE-----P 465

Query: 447 AASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVE 506
           A +       T PKE A      A       +P    +  T   +        P+P    
Sbjct: 466 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--------PSP---- 513

Query: 507 KTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSG 566
                     TK     +  EP P  P   ++P    P   + T+P K+  P    +P+ 
Sbjct: 514 --------TTTKEPAPTTPKEPAPTTP---KKPAPTTPKEPAPTTP-KEPAPTTTKKPAP 561

Query: 567 PLPAKASPLSTK--ASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPP 624
             P + +P + K  A   P K +P      A    + P+    ++    T  EP P  P 
Sbjct: 562 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 621

Query: 625 ETTPT--------------PATPKVKSGVRRAEPA-TPVVKAVPEAPKGGEAEDLVGKPY 669
           E  PT              P TPK  +     EPA T   +  P  PKG     L     
Sbjct: 622 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 681

Query: 670 SQDASRSPQSLSDT 683
           +     +P+ L+ T
Sbjct: 682 TTPKKPAPKELAPT 695



 Score = 82.0 bits (201), Expect = 1e-14
 Identities = 146/706 (20%), Positives = 221/706 (31%), Gaps = 104/706 (14%)

Query: 15  PLPPGGAGPGPGPG--PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPG 72
           P P     P P     P P   K P AP      P      +   P  P P     P P 
Sbjct: 355 PAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 413

Query: 73  PGSTSRRLDPKEPLGNQRAASPT---------PKQASATTPGHESPRETRAQGPAGQEAD 123
                    PKEP    +  +PT         PK+ + TTP   +P   +   P   +  
Sbjct: 414 TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 473

Query: 124 GPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
            P    +    T +S  + +  P   +T ++P +  + +P  +    P        +TP 
Sbjct: 474 SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 533

Query: 184 QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLH 243
           +P   T  +       +    P P  T+           + A      TAP +  +    
Sbjct: 534 KPAPTTPKEPAPTTPKE----PAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPT 586

Query: 244 SPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVS 303
           +P      +P K     P++     P  P P + +     A + P  A    P E     
Sbjct: 587 TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPNTPKE----- 638

Query: 304 PQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST 363
           P P  P +P+   P+ PA   P ++A   P G                       T  +T
Sbjct: 639 PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG-----------------------TAPTT 675

Query: 364 LMSVQPEADTQGQPAPSKGTPKIVFNDAS----KEAGPKPLGSGP--GPGPAPGAKTEPG 417
           L   +P   T  +PAP +  P       S    K A   P G+ P     PAP    EP 
Sbjct: 676 LK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 733

Query: 418 ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSK 477
                G+ P  L +   TT  K    E    +       T  K     P   A       
Sbjct: 734 PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 793

Query: 478 SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTS- 536
           +P      TT +          P P   E          T       +  PT    PT+ 
Sbjct: 794 AP------TTPK---------KPAPTTPE----------TPPPTTSEVSTPTTTKEPTTI 828

Query: 537 -QQPPVGAPHRASGTSP-LKQKGPQGLGQPSGPLPAKASPLST------------KASPL 582
            + P    P  ++  +P   +  P+  G P+   PA   P  T            + +P 
Sbjct: 829 HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 888

Query: 583 PSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT---PTPATPKVKSGV 639
            + A+P+     A+   KT  S     T   T        P + T    T   PKV +  
Sbjct: 889 TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT-T 947

Query: 640 RRAEPATPVVKAVPEA--PKGGEAEDLVGKPYSQDASRSPQSLSDT 683
           ++    T ++    E   PK          P  Q  +++P+  + T
Sbjct: 948 KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 993



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 146/715 (20%), Positives = 239/715 (33%), Gaps = 89/715 (12%)

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQR 1066
            D+S ++  ++  + +   A+  +  P LP   D+S+E  L   +E   E ++     +Q 
Sbjct: 196  DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 255

Query: 1067 IRSTARKTRRDKEELRAQRRRERSKTPPSNL--SPIEDASPTEE------LRQAAEMEEL 1118
                  KT   KE    ++   +   P S +   P   A  T +       ++       
Sbjct: 256  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 315

Query: 1119 HRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSG 1178
              +S +   P+P+    A      P+      +    PT     +PT T   + TTP   
Sbjct: 316  EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPTTTKEPAPTTPKEP 371

Query: 1179 RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG 1238
             P  + E A      K+     ++      + P   P+ P  P      E   TT +E  
Sbjct: 372  APTTTKEPA--PTTTKSAPTTPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPA 427

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYM 1298
               +  A  TP        ++   T+                     KE     A +   
Sbjct: 428  PTTKEPAPTTPKEPAPTAPKKPAPTTP--------------------KEP----APTTPK 463

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            +P        +P T+P + A   + S PT++             T      T       +
Sbjct: 464  EPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 522

Query: 1359 SPASPSSASKEIGMPFSQGPGTPA-TTAVAPCPAGLPR-GYMTPASPAGSERSPSPSSTA 1416
            +P  P+  + +   P +  P  PA TT   P P    +    TP  PA +    +  +T 
Sbjct: 523  TPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 580

Query: 1417 HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASS 1476
                 +PTT    + T     AP+          E+P   +  E     P  A       
Sbjct: 581  KKL--TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 638

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA----PASDMPRSPG----APT--- 1525
              P +P  P+ +    P    P+ TA  + +  +P     PA   P+ P     APT   
Sbjct: 639  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 698

Query: 1526 ---------PSPMVAQGTQ----------TPHRPS--TPRLVWQESSQE-APFMVITLAS 1563
                     P+P   +GT           TP  P+  TP+     + +E AP      A 
Sbjct: 699  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758

Query: 1564 DASSQTRMVHASASTSPLCSPT---ETQPTTHGY-SQTTPPSVSQLPPEPPGPPGFPRVP 1619
               + T     +++TS   +PT   ET PTT    + TTP   +   PE P P       
Sbjct: 759  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 818

Query: 1620 SAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKP 1674
                  P  ++      + + S   +S+ P    +E  P+ PG        A KP
Sbjct: 819  PTTTKEPTTIH-----KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 868



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 138/686 (20%), Positives = 210/686 (30%), Gaps = 68/686 (9%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKP----PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG 70
            P  P    P     P P   +P    P  PA     P A    +   P  P P     P 
Sbjct: 412  PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-----PTAPKKPAPTTPKEPAPTTPKEPA 466

Query: 71   PGPGSTSRRLDPKEPL--------GNQRAASPTPKQASATTPGHESPRETRAQGPAGQEA 122
            P          PKEP            +  +PT  +++ TTP   SP  T+   P   + 
Sbjct: 467  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 526

Query: 123  DGPRRTLQVDSRTQR-----SGRSPSVSPDRGSTPT-----SPYSVPQIAPLPSSTLCPI 172
              P    +    T +     + + P+ +  +   PT     +P +  + AP     L P 
Sbjct: 527  PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 586

Query: 173  CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232
                   +TP +P   T      ++       P P   +           + A       
Sbjct: 587  TPEKLAPTTPEKPAPTT----PEELAPTTPEEPTPTTPE-----------EPAPTTPKAA 631

Query: 233  APRSKSQQQLHSPALSPAHSPAKQPL-GKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
            AP +  +    +P   PA +  K+P    P +     P G  P + +         P P 
Sbjct: 632  APNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 690

Query: 292  QAA-----APPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGL 346
            + A      P       P P  P   +   P+ PA   P + A   P G   T   +   
Sbjct: 691  ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 750

Query: 347  TGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP-KPLGSGPG 405
            T         L    +   +  P + T  +PAP+  TPK       KE  P  P    P 
Sbjct: 751  TTPKKPAPKEL----APTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPKKPAPT 804

Query: 406  PGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAIC 465
                P   T   +       P  + K+   ++P+        A + + K   +P  +   
Sbjct: 805  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 864

Query: 466  PLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSL 525
                             +  TT             T    EKT    +   T ++   + 
Sbjct: 865  ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 924

Query: 526  GEPTPLP----PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASP 581
             + TP        T+  P V    +   T+ +  K P+   +P     A  S  +T    
Sbjct: 925  QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK-PEETAKPKD--RATNSKATTPKPQ 981

Query: 582  LPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRR 641
             P+KA    KP    +P   P   + K T  P K   M    PE  PT    +       
Sbjct: 982  KPTKA--PKKPTSTKKPKTMPRVRKPKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 1036

Query: 642  AEPATPVVKAVPEAPKGGEAEDLVGK 667
                TP  K V   PK  +A    G+
Sbjct: 1037 RPNQTPNSKLVEVNPKSEDAGGAEGE 1062



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 148/707 (20%), Positives = 228/707 (32%), Gaps = 83/707 (11%)

Query: 952  PDPSLDREPELEME-SLTGSPEDRSRGEHSSTL--PASTPSYTSGTSPTSLSSLEEDS-- 1006
            P PSL    +   E SLT + E     + ++T     ST      TS     S+E+ S  
Sbjct: 219  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLL-----PTIEDSSEEEELREEEELLREQEKMRE 1061
            D +P+ +     AK   KA   + GP L     PT     E      +E      +    
Sbjct: 279  DLAPTSKVL---AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 335

Query: 1062 VEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRS 1121
              ++   +T +      +E      +E + T P   +P     P     ++A       +
Sbjct: 336  TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 395

Query: 1122 SCSEYSPSPSLDSEA------EALDGGPSRLYKSGSE-------YNLPTFMSLYSPTETP 1168
              +   P+P+   E       E     P     +  E          PT     +PT   
Sbjct: 396  PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 455

Query: 1169 SGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE 1228
              + TTP    P  + E +       A    +          P    S PT P+     E
Sbjct: 456  EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-----E 510

Query: 1229 YQDTTDREYGQAA-QPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKE 1287
               TT +E      +  A  TP        +E   T+    +    ++         K+ 
Sbjct: 511  PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEP 567

Query: 1288 KQFLNAESAYMDPMK------QNGGPLTPG----TSPTQLAAPVSFSTPTSSDSSGGRVI 1337
                  E+A   P K      +   P TP     T+P +LA P +   PT +        
Sbjct: 568  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPEEPTPTTPEEPAPT 626

Query: 1338 PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGY 1397
                   +  KE         +P +P   +     P    P TP  TA        P   
Sbjct: 627  TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKEPAPT-- 682

Query: 1398 MTPASPAGSERSPS----PSSTAHSY-------GHSPTTANYGSQT---EDLPQAPSGLA 1443
             TP  PA  E +P+    P+ST           G +PTT    + T   E  P  P G A
Sbjct: 683  -TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 741

Query: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
                     P +  +     P P+           P +   P+ + +  P    P+ TA 
Sbjct: 742  ---------PTTLKE-----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 787

Query: 1504 FSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLA 1562
             + + P+P  P    P +P  P P+        T   P+T      ES+ E        A
Sbjct: 788  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847

Query: 1563 SDASSQTRMVHAS---ASTSPLCSPTETQPTTHGYSQTTPPSVSQLP 1606
             + S +   V  +   A+T P  + T    TT    +TTP + +  P
Sbjct: 848  LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 894



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 169/851 (19%), Positives = 268/851 (31%), Gaps = 151/851 (17%)

Query: 1161 LYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTG 1220
            +++PT  PS     P SG     A +  +   +++                   P  P  
Sbjct: 66   VHNPTSPPSSKKAPPPSG-----ASQTIKSTTKRS-------------------PKPPNK 101

Query: 1221 PRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAF 1280
             +     E ++ T+       Q ++  + +S  ++   +I  +  S      A++R+L  
Sbjct: 102  KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNS------AANRELQK 155

Query: 1281 AEDKKKEKQFLNAESAYMDP--MKQNGGPL--------TPGTSPTQ-----------LAA 1319
                K  K+    +     P  + + G  L        TP TS TQ            A 
Sbjct: 156  KLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 215

Query: 1320 PVSF--STPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASP--SSASKEIGMPFS 1375
            P++   S P +SD+S    +   + T    KET    K  S+      +SA +   +  +
Sbjct: 216  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 275

Query: 1376 QGPGTPATTAVAPCPAGLPRGYMTPASPA-GSERSPSPSSTAHSYGHSPTTANYGSQTED 1434
                   T+ V   P   P+   T   PA  + + P+P           TT    + T  
Sbjct: 276  SAKDLAPTSKVLAKPT--PKAETTTKGPALTTPKEPTP-----------TTPKEPASTTP 322

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG 1494
                P+ + +A    +E            P P+       + S P +P  P+ + T  P 
Sbjct: 323  KEPTPTTIKSAPTTPKE------------PAPT------TTKSAPTTPKEPAPTTTKEPA 364

Query: 1495 KMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR--PSTPRLVWQESSQ 1552
               P+  A  +T+ P+P      P +P  P P+        TP    P+TP+     + +
Sbjct: 365  PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 424

Query: 1553 E-APFMVITLASDASSQTRMVHASASTSPL-CSPTETQPTT-HGYSQTTPPSVSQLPPEP 1609
            E AP    T    A +  +    +A   P   +P E  PTT    + TT    S   P+ 
Sbjct: 425  EPAP----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 480

Query: 1610 PGPPGFPRVPSAGAD-GPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDL 1668
            P P      P+   +  P         P E          P T + EP P TP       
Sbjct: 481  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAP-- 537

Query: 1669 RTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLAT 1728
             T  +P P    +     T           A  P   +++    P  +     E     T
Sbjct: 538  TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTT 595

Query: 1729 ATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRS 1788
                + T    +     ++P                             E+   T P  +
Sbjct: 596  PEKPAPTTPEELAPTTPEEPT------------------------PTTPEEPAPTTPKAA 631

Query: 1789 GP----RGRPREAKFARYNLPNQVAPLARRDVL-ITQMGTAQSIGLKPGPVPEPGAEPHR 1843
             P       P   K      P + AP   ++    T  GTA +   +P P       P  
Sbjct: 632  APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 691

Query: 1844 ATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDM 1903
              P   +        KP        +GTA T     P+EPA     T   P         
Sbjct: 692  LAPTTTKEPTSTTCDKPAPTT---PKGTAPTT----PKEPA---PTTPKEPAP------- 734

Query: 1904 VYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRD-PEPPEPPTYRAQGVVG 1962
                P G++ T    PAP+ P+K       P  +  P     D P P  P          
Sbjct: 735  --TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 792

Query: 1963 PGPHEEQRPYP 1973
            P P   ++P P
Sbjct: 793  PAPTTPKKPAP 803



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 138/639 (21%), Positives = 209/639 (32%), Gaps = 122/639 (19%)

Query: 1347 AKETQDPLKLHSSPASPSSA--------------SKEIGMPFSQGPGTP----ATTAVAP 1388
            AKETQ   K  +   +P+S                  +  P    P TP    +TT   P
Sbjct: 266  AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 325

Query: 1389 CPAGLPRGYMTPASPAGSE--------RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
             P  +     TP  PA +         + P+P++T      +PTT    + T     AP+
Sbjct: 326  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP---APTTPKEPAPTTTKEPAPT 382

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
               +A    +E P   +  +     P            P +P  P+ + T  P    P+ 
Sbjct: 383  TTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-TKEPAPTTPKE 440

Query: 1501 TAEFSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
             A  + + P+P  P    P +P  P P+      T     P+TP+       + AP    
Sbjct: 441  PAPTAPKKPAPTTPKEPAPTTPKEPAPT------TTKEPSPTTPK-------EPAP---- 483

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQP-TTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
            T    A + T+    + + S   +P E  P TT   + TTP   +   P+ P P   P+ 
Sbjct: 484  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKE 542

Query: 1619 PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPII 1678
            P+               P E          P T + EP P TP          + PT   
Sbjct: 543  PAP------------TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPT--- 586

Query: 1679 LTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMAS 1738
             T + +  T+    A      L P    + T   P                   +   A+
Sbjct: 587  -TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--------------EEPAPTTPKAA 631

Query: 1739 SVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAK 1798
            +    ++  P    +P  +         +P   A     E A  T P  + P      A 
Sbjct: 632  APNTPKEPAPTTPKEPAPT---------TPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP 681

Query: 1799 FA-RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGA 1857
               +   P ++AP   ++   T          KP P    G  P   TP E      P  
Sbjct: 682  TTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAP--TTPKE------PAP 726

Query: 1858 RKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTF 1917
              P        +GTA T      +EPA     T  +P  +    ++      G + T + 
Sbjct: 727  TTPKEPAPTTPKGTAPTTL----KEPA---PTTPKKPAPK----ELAPTTTKGPTSTTSD 775

Query: 1918 HPAPSVPEKSMADAAP--PGQSSSPFYGPRDPEPPEPPT 1954
             PAP+ P K  A   P  P  ++     P  PE P P T
Sbjct: 776  KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 813



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 50/201 (24%), Positives = 73/201 (36%), Gaps = 26/201 (12%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSG----GPTQNGFPAHQAPTYPGPST--YPAPAF 3094
            AP TP  PT        P  P+ +A +      PT    PA   P  P P+T    AP  
Sbjct: 608  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 667

Query: 3095 PPGAS-------YPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQ 3147
            P G +        P  P  P  +   PT      T  PT+ +   P P         P+ 
Sbjct: 668  PKGTAPTTLKEPAPTTPKKPAPKELAPT-----TTKEPTSTTCDKPAPTT-------PKG 715

Query: 3148 TSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVS 3207
            T+    ++  PT  +  A P  P  +AP+      P         ++      G   + S
Sbjct: 716  TAPTTPKEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 774

Query: 3208 QSPAPTYPSDSHYTSLEQNVP 3228
              PAPT P ++  T+ ++  P
Sbjct: 775  DKPAPTTPKETAPTTPKEPAP 795



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 15/216 (6%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +K+ S      PA   +
Sbjct: 432  EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-----TTTKEPSPTTPKEPAPTTT 486

Query: 3738 KAEPQA--QPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALT 3795
            K+ P    +P     ++AP   +  SP++ + P+    ++P     ++     P + A T
Sbjct: 487  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 546

Query: 3796 QAR-----LQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA 3849
              +       ++  PTT +  AP   +      P   T T P+   P   E+   +    
Sbjct: 547  TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606

Query: 3850 KAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
             AP     P       P P   KA A    TP  PA
Sbjct: 607  LAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPA 640



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 116/553 (20%), Positives = 190/553 (34%), Gaps = 79/553 (14%)

Query: 2882 SALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKAS-- 2939
            S  PPN   +K K+ + S    E H     Q S    ++S      +  +T+   K+S  
Sbjct: 95   SPKPPNK--KKTKKVIESEEITEEHSVSENQESSSSSSSS------SSSSTIRKIKSSKN 146

Query: 2940 --LLRELDRDLRLVEHESTKLRKKQAE----LDEEEKEIDA---KLKYLELGITQRKE-- 2988
                REL + L++ +++  + +KK       +DE    +D    K+   +   TQ  +  
Sbjct: 147  SAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVS 206

Query: 2989 SLAKDRGGRDYPPLRGLGEHRDYLSDSELN-----------------QLRLQGC--TTPA 3029
            +  K    +   P   L  + D   ++ L                  Q    G   TT A
Sbjct: 207  TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 266

Query: 3030 GQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTY 3089
             +      T+A    P+     +      P P+    + GP     P    PT P     
Sbjct: 267  KETQSIEKTSAKDLAPTSKVLAK------PTPKAETTTKGPALTT-PKEPTPTTPKEPAS 319

Query: 3090 PAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT----PMPTTQSTLFPVPADSRAPLQKP 3145
              P  P   +  + P  P + A  PT   +  T    P PTT  T  P P   + P    
Sbjct: 320  TTPKEPTPTTIKSAPTTPKEPA--PTTTKSAPTTPKEPAPTT--TKEPAPTTPKEPAPTT 375

Query: 3146 RQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGS 3205
             +       +  PT  +  A P  P   AP  T+   PA ++  E    P  P+  +   
Sbjct: 376  TKEPAPTTTKSAPTTPKEPA-PTTPKKPAP--TTPKEPAPTTPKE--PTPTTPK--EPAP 428

Query: 3206 VSQSPAPTYPSDSHYTSLEQNVPRN------YVMIDDISELTKDSTSTAPDSQRLEPLGP 3259
             ++ PAPT P +   T+ ++  P            +     TK+ + T P  +   P   
Sbjct: 429  TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTT 486

Query: 3260 GSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPAST-- 3317
             S+    KEP        PT P      +E S   + +P        +  +  +PA T  
Sbjct: 487  KSAPTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 540

Query: 3318 HYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEE 3377
                 +  +  A      P P  PK P+ +  P   +    K       +K++  +P + 
Sbjct: 541  KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKP 599

Query: 3378 AKDVESDLASYPP 3390
            A     +LA   P
Sbjct: 600  APTTPEELAPTTP 612



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 130/638 (20%), Positives = 213/638 (33%), Gaps = 90/638 (14%)

Query: 952  PDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPS 1011
            P P+  +EP     + T  P   +  E + T   S P+ T   +PT+  S    +   PS
Sbjct: 457  PAPTTPKEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT-TPKEPS 512

Query: 1012 RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTA 1071
                 E A               PT          ++      ++      ++    +T 
Sbjct: 513  PTTTKEPA---------------PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 557

Query: 1072 RKTRRDKEELRAQRRRERSKTPPSNLSPI--EDASPTEELRQAAEM-EELHRSSCSEYSP 1128
            +      +E      +E + T P  L+P   E  +PT   + A    EEL  ++  E +P
Sbjct: 558  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 617

Query: 1129 S----PSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSA 1184
            +    P+  +   A    P     +  +   PT     +PT     + TTP    P    
Sbjct: 618  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 677

Query: 1185 EEAYEEMMRKA--ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE------ 1236
            E A     + A  EL      +          P+ P G       E   TT +E      
Sbjct: 678  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 737

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESA 1296
             G A     E  P +      +E+  T+    +   +++ D       K+       E A
Sbjct: 738  KGTAPTTLKEPAPTTPKKPAPKELAPTT---TKGPTSTTSDKPAPTTPKETAPTTPKEPA 794

Query: 1297 YMDPMKQNGGPLTPGTSP---TQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
               P K    P TP T P   ++++ P +   PT+   S     PD    +  A+ T  P
Sbjct: 795  PTTPKKP--APTTPETPPPTTSEVSTPTTTKEPTTIHKS-----PDESTPELSAEPT--P 845

Query: 1354 LKLHSSPASPSSASKEIGMPFSQGPG---------------------TPATTAVAPCPAG 1392
              L +SP       KE G+P ++ P                      TP TT  AP    
Sbjct: 846  KALENSP-------KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP---- 894

Query: 1393 LPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREK 1452
                 MT  +   +E++     TA +   + TT    +  +      + LA      ++ 
Sbjct: 895  ----KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 950

Query: 1453 PLSA---SDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG-KMGPRATAEFSTQT 1508
              +    +  E       RA +  A++  P  P+   + PT +   K  PR     +T T
Sbjct: 951  ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 1010

Query: 1509 PSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
            P     S MP        +  + Q T  P++    +LV
Sbjct: 1011 PRKM-TSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLV 1047



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 51/242 (21%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSS-AEYSQPSRASSAYH 3716
            T +EP   A K  A    +  A P +    AP   K+  P  P   A  +  S  ++   
Sbjct: 437  TPKEPAPTAPKKPAPTTPKEPA-PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQP 3776
             A  + K +      P+   +K      P    ++ AP   +  +P++ + P+    ++P
Sbjct: 496  PAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP 551

Query: 3777 QTQQQQQGLGLQPPQQALTQARLQQQSQPTT----RGSAPAASQPAGKPQPGPSTA---- 3828
                 ++     P + A T  +   ++ PTT      + P    P    +P P+T     
Sbjct: 552  APTTTKKPAPTTPKEPAPTTPK---ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 608

Query: 3829 -TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ 3887
             T P+   P   E+   +   A AP   + P       P P   K  A       AP   
Sbjct: 609  PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 668

Query: 3888 PG 3889
             G
Sbjct: 669  KG 670



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 8/211 (3%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+   P  P      T  E  PSP    +  P   +        P+  T ++A  
Sbjct: 449  PAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 506

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPM-IAPRV 2251
                   T      P T +  +   P           +      P  + T+ P    P+ 
Sbjct: 507  TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 566

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T     P   +  +  + P    P    KPA    P    P+ PE P     EEP 
Sbjct: 567  PAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPA 624

Query: 2312 PTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            PTT  AA       PAP      K PA   P
Sbjct: 625  PTTPKAAAPNTPKEPAPTT---PKEPAPTTP 652



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/230 (24%), Positives = 73/230 (31%), Gaps = 23/230 (10%)

Query: 2132 GPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAAD 2191
            GP L+ P+   P  P    + T  E  P+    A   P     T  +   P+T    A  
Sbjct: 300  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPT 358

Query: 2192 GMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV 2251
                    TP       T +PA             P  +      P T     P   P+ 
Sbjct: 359  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKE 417

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T   + PAP+    A + P    P    KPA         P+ P+ P     +EP 
Sbjct: 418  PTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPA---------PTTPKEPAPTTPKEPA 466

Query: 2312 PTTT----PAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
            PTTT    P   KE      PAP   +  P        +   S P   KE
Sbjct: 467  PTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 510



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 44/238 (18%), Positives = 78/238 (32%), Gaps = 16/238 (6%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            T +EP     K  A    +  A P +   +AP  PKK  P  P     + P + +     
Sbjct: 547  TPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 605

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ-- 3775
                        + P    +   P+A      ++ AP   +  +P++ + P+    ++  
Sbjct: 606  ELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 664

Query: 3776 PQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRG------------SAPAASQPAGKPQP 3823
            P T +      L+ P     +    ++  PTT              + P  + P    +P
Sbjct: 665  PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 724

Query: 3824 GPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTP 3881
             P+T   P P  P     T   +     P++    +  P    GP    +      TP
Sbjct: 725  APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 19/235 (8%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+ L P  P     PT PE  P+P       P A      ++  P+T    A   
Sbjct: 599  PAPTTPEELAPTTPEE-PTPTTPE-EPAPTT-----PKAAAPNTPKEPAPTTPKEPAPTT 651

Query: 2193 MIYSTINTP--IAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPR 2250
                   TP   A T P  T P ++  P               T     + T     AP 
Sbjct: 652  PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711

Query: 2251 VPLG--PTGLYRYPAPS--RFPIASSVPPAEGPVYLGKPAAAK----APGAGGPSRPEMP 2302
             P G  PT   + PAP+  + P A + P    P  L +PA       AP    P+  + P
Sbjct: 712  TPKGTAPT-TPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 769

Query: 2303 VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
                 ++P PTT           PAP       P     P   +  +S P   KE
Sbjct: 770  TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 824



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 3026 TTPAGQFVDFPATAA-------APATPSG--PTAFQQPRF---QPPAPQYSAGSGGPTQN 3073
            TTP G     P   A       AP TP G  PT  ++P     + PAP+  A    PT  
Sbjct: 711  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA----PTTT 766

Query: 3074 GFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFP 3133
              P       P P+T P    P     PA P  P + A  PT     +TP PTT     P
Sbjct: 767  KGPTSTTSDKPAPTT-PKETAPTTPKEPA-PTTPKKPA--PT---TPETPPPTTSEVSTP 819

Query: 3134 VPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV---VPMSSAPSET 3178
                    + K    S  +L  + PT   +  SP    VP +  P+ T
Sbjct: 820  TTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAAT 866



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 28/216 (12%)

Query: 2138 PQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTA---VRQLLPSTATVRAADGMI 2194
            P    P  P     PT P+  P+P    +  P   +GTA   +++  P+T    A   + 
Sbjct: 639  PAPTTPKEPA----PTTPK-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693

Query: 2195 YSTINTPIAATL--PITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
             +T   P + T   P  T P        +            T    T+ T +   AP  P
Sbjct: 694  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753

Query: 2253 LGPTGLYRYPAPSRFPIA--SSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEP 2310
              P      P  ++ P +  S  P    P    K  A   P    P+ P+ P     E P
Sbjct: 754  KKPAPKELAPTTTKGPTSTTSDKPAPTTP----KETAPTTPKEPAPTTPKKPAPTTPETP 809

Query: 2311 LPTT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
             PTT    TP   KE        P    K P ++ P
Sbjct: 810  PPTTSEVSTPTTTKE--------PTTIHKSPDESTP 837



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 34/178 (19%), Positives = 62/178 (34%), Gaps = 11/178 (6%)

Query: 3687 SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQ 3746
            SAP  PK+  P    SA  +    A +       +K+ +      PA   +K     +P 
Sbjct: 332  SAPTTPKEPAPTTTKSAPTTPKEPAPTT------TKEPAPTTPKEPAPTTTK-----EPA 380

Query: 3747 LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT 3806
                ++AP   +  +P++ + P+    ++P     ++     P + A T       +   
Sbjct: 381  PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 440

Query: 3807 TRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAP 3864
               +AP    P    +P P+T   P P        T   +      +       +PAP
Sbjct: 441  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 498



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 45/236 (19%), Positives = 71/236 (30%), Gaps = 30/236 (12%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +KK +      PA    
Sbjct: 518  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKKPAPTTPKEPAPTTP 572

Query: 3738 KAEPQAQPQ------------LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGL 3785
            K      P+                + AP   +  +P++ + P+     +P     +   
Sbjct: 573  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632

Query: 3786 GLQPPQQALTQARLQQQSQPTTRG-SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +    + P     + P  + P       P+T   P P  P +      
Sbjct: 633  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692

Query: 3845 SKGTAKAP------------QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            +  T K P             +G AP     P P      A   P GT      +P
Sbjct: 693  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 748



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 37/121 (30%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 2239 TSLTRVPMIAPRVP--LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP 2296
            T+ T    + P  P  L PT   + PAP+     +   P E      +  A   P A  P
Sbjct: 575  TAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 633

Query: 2297 SRPEMPVGAAREEPLPTT----TPAAIKEAA------GAPA----PAPLAGQKP-PADAA 2341
            + P+ P     +EP PTT     P   KE A       AP     PAP   +KP P + A
Sbjct: 634  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693

Query: 2342 P 2342
            P
Sbjct: 694  P 694



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 48/244 (19%), Positives = 81/244 (33%), Gaps = 31/244 (12%)

Query: 3657 HTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYH 3716
            +T +EP     K  A    +  A P +   +AP  PK   P        + P + +    
Sbjct: 634  NTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 692

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQG----RQAAPGPQQSQSPSSRQIPSGAA 3772
              + +K+ +      PA    K      P+       ++ AP   +  +P++ + P+   
Sbjct: 693  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 752

Query: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQ 3832
             ++P  ++      L P       +    +  PTT    P  + P    +P P+T   P 
Sbjct: 753  PKKPAPKE------LAPTTTKGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPKKPA 802

Query: 3833 PAGPPRAEQTNGSKGTA----------KAPQQGRAP-QAQPAP-----GPGPAGVKAGAR 3876
            P  P     T     T           K+P +      A+P P      P   GV     
Sbjct: 803  PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 862

Query: 3877 PGGT 3880
            P  T
Sbjct: 863  PAAT 866



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 52/214 (24%), Positives = 70/214 (32%), Gaps = 17/214 (7%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  +AP+   P  P     PT P+  P+P    +  P     T  ++  P+T        
Sbjct: 441  PAPTAPKKPAPTTPKEPA-PTTPK-EPAPTTTKEPSP-----TTPKEPAPTTTKSAPTTT 493

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
               +   T  A T P    P +   P        P  +      P T     P   P+ P
Sbjct: 494  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPT-TPKEP 551

Query: 2253 LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLP 2312
               T   + PAP+     +   P E      K      P    P+ PE P     EE  P
Sbjct: 552  APTTT--KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 609

Query: 2313 TT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            TT    TP   +E   AP     A    P + AP
Sbjct: 610  TTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 641



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 41/212 (19%), Positives = 78/212 (36%), Gaps = 20/212 (9%)

Query: 3682 HSQPSSAP----AMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK----GSRQAHSGPA 3733
            H++ S++P    A P   +P  P +++ S+ +  +       ++K+      + +  G  
Sbjct: 202  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 261

Query: 3734 ALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSR-----QIPSGAASRQPQTQQQQQGLGLQ 3788
               S  E Q+  +   +  AP  +    P+ +     + P+    ++P     ++     
Sbjct: 262  KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 321

Query: 3789 PPQQALTQAR----LQQQSQPTTRGSAPAA-SQPAGKPQPGPSTATGPQPAGPPRAEQTN 3843
            P +   T  +      ++  PTT  SAP    +PA      P+  T  +PA  P   +  
Sbjct: 322  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEP 379

Query: 3844 GSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
                T  AP   + P       P P   K  A
Sbjct: 380  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 411



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 46/210 (21%), Positives = 65/210 (30%), Gaps = 8/210 (3%)

Query: 2152 PTFPEGHPSPGNLAQYGPAAGQG--TAVRQLLPSTATVRAADGMIYSTINTPIAATLPIT 2209
            PT P+  P+P    +  P   +   T  ++  P+T    A          TP   T    
Sbjct: 365  PTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 423

Query: 2210 TQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPI 2269
             +PA   +         P  +      P T     P   P+ P   T     P   + P 
Sbjct: 424  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPTTPKEPA 482

Query: 2270 ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPA 2329
             ++   A  P    +PA      A  P+ P+ P     +EP PTT           PAP 
Sbjct: 483  PTTTKSA--PTTTKEPAPTTTKSA--PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 538

Query: 2330 PLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
                  P     P   +     P   KE A
Sbjct: 539  TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 568



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 37/209 (17%), Positives = 69/209 (33%), Gaps = 6/209 (2%)

Query: 3667 AKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            +K  A+   + E        + P  P    P  P+S    +P+  +      +  +    
Sbjct: 284  SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 343

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS-RQPQTQQQQQGL 3785
               S P   +  A    +         P P  ++ P+     S   + ++P     ++  
Sbjct: 344  TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 403

Query: 3786 GLQPPQQALTQARLQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +   +  PTT +  AP   +PA      P+  T P+   P   ++   
Sbjct: 404  PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEPAP 459

Query: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKA 3873
            +     AP   + P       P P   K+
Sbjct: 460  TTPKEPAPTTTKEPSPTTPKEPAPTTTKS 488


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 143/674 (21%), Positives = 235/674 (34%), Gaps = 73/674 (10%)

Query: 36  PPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPT 95
           P S P+     P +GA+++        P P     P    T + ++ +E +  + + S  
Sbjct: 110 PTSPPSSKKAPPPSGASQTIKSTTKRSPKP-----PNKKKTKKVIESEE-ITEEHSVSEN 163

Query: 96  PKQASATTPGHESP--RETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSP---DRGS 150
            + +S+++    S   R+ ++   +    +  ++    D++  R+ + P+  P   D   
Sbjct: 164 QESSSSSSSSSSSSTIRKIKSSKNSAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAG 223

Query: 151 TPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLT 210
           +           P  S+T      TS   +T    N       ++    +     N   T
Sbjct: 224 SGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETT 283

Query: 211 -QVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGP 269
            + KE    N Q         T+A  ++S ++  +  L+P      +P  K +   ++GP
Sbjct: 284 VETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETT-TKGP 342

Query: 270 GGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSA 329
               P      T +  +   P +    P   + +P  P+   P+T +  P   + PA + 
Sbjct: 343 ALTTPKEPTPTTPKEPASTTPKEPT--PTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTT 400

Query: 330 TAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFN 389
           T  PA    T +     T K     A   T+++     +P   T  +PAP+  TPK    
Sbjct: 401 TKEPAP--TTPKEPAPTTTKE---PAPTTTKSAPTTPKEPAPTTPKKPAPT--TPKEPAP 453

Query: 390 DASKEAGPKPLGSGPGPG---PAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQ 446
              KE  P      P P    PAP    EP A   P       PK    T+PK       
Sbjct: 454 TTPKEPTPTT-PKEPAPTTKEPAPTTPKEP-APTAPKKPAPTTPKEPAPTTPKE-----P 506

Query: 447 AASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVE 506
           A +       T PKE A      A       +P    +  T   +        P+P    
Sbjct: 507 APTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKE--------PSP---- 554

Query: 507 KTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSG 566
                     TK     +  EP P  P   ++P    P   + T+P K+  P    +P+ 
Sbjct: 555 --------TTTKEPAPTTPKEPAPTTP---KKPAPTTPKEPAPTTP-KEPAPTTTKKPAP 602

Query: 567 PLPAKASPLSTK--ASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPP 624
             P + +P + K  A   P K +P      A    + P+    ++    T  EP P  P 
Sbjct: 603 TTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPE 662

Query: 625 ETTPT--------------PATPKVKSGVRRAEPA-TPVVKAVPEAPKGGEAEDLVGKPY 669
           E  PT              P TPK  +     EPA T   +  P  PKG     L     
Sbjct: 663 EPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAP 722

Query: 670 SQDASRSPQSLSDT 683
           +     +P+ L+ T
Sbjct: 723 TTPKKPAPKELAPT 736



 Score = 82.0 bits (201), Expect = 1e-14
 Identities = 146/706 (20%), Positives = 221/706 (31%), Gaps = 104/706 (14%)

Query: 15   PLPPGGAGPGPGPG--PGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPG 72
            P P     P P     P P   K P AP      P      +   P  P P     P P 
Sbjct: 396  PAPTTTKEPAPTTPKEPAPTTTKEP-APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT 454

Query: 73   PGSTSRRLDPKEPLGNQRAASPT---------PKQASATTPGHESPRETRAQGPAGQEAD 123
                     PKEP    +  +PT         PK+ + TTP   +P   +   P   +  
Sbjct: 455  TPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEP 514

Query: 124  GPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
             P    +    T +S  + +  P   +T ++P +  + +P  +    P        +TP 
Sbjct: 515  SPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPK 574

Query: 184  QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLH 243
            +P   T  +       +    P P  T+           + A      TAP +  +    
Sbjct: 575  KPAPTTPKEPAPTTPKE----PAPTTTKKP---APTTPKEPAPTTPKETAPTTPKKLTPT 627

Query: 244  SPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVS 303
            +P      +P K     P++     P  P P + +     A + P  A    P E     
Sbjct: 628  TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEP---APTTPKAAAPNTPKE----- 679

Query: 304  PQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAST 363
            P P  P +P+   P+ PA   P ++A   P G                       T  +T
Sbjct: 680  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKG-----------------------TAPTT 716

Query: 364  LMSVQPEADTQGQPAPSKGTPKIVFNDAS----KEAGPKPLGSGP--GPGPAPGAKTEPG 417
            L   +P   T  +PAP +  P       S    K A   P G+ P     PAP    EP 
Sbjct: 717  LK--EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPA 774

Query: 418  ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSK 477
                 G+ P  L +   TT  K    E    +       T  K     P   A       
Sbjct: 775  PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEP 834

Query: 478  SPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTS- 536
            +P      TT +          P P   E          T       +  PT    PT+ 
Sbjct: 835  AP------TTPK---------KPAPTTPE----------TPPPTTSEVSTPTTTKEPTTI 869

Query: 537  -QQPPVGAPHRASGTSP-LKQKGPQGLGQPSGPLPAKASPLST------------KASPL 582
             + P    P  ++  +P   +  P+  G P+   PA   P  T            + +P 
Sbjct: 870  HKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPE 929

Query: 583  PSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT---PTPATPKVKSGV 639
             + A+P+     A+   KT  S     T   T        P + T    T   PKV +  
Sbjct: 930  TTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTT-T 988

Query: 640  RRAEPATPVVKAVPEA--PKGGEAEDLVGKPYSQDASRSPQSLSDT 683
            ++    T ++    E   PK          P  Q  +++P+  + T
Sbjct: 989  KKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTST 1034



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 146/715 (20%), Positives = 239/715 (33%), Gaps = 89/715 (12%)

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQR 1066
            D+S ++  ++  + +   A+  +  P LP   D+S+E  L   +E   E ++     +Q 
Sbjct: 237  DTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQT 296

Query: 1067 IRSTARKTRRDKEELRAQRRRERSKTPPSNL--SPIEDASPTEE------LRQAAEMEEL 1118
                  KT   KE    ++   +   P S +   P   A  T +       ++       
Sbjct: 297  STDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPK 356

Query: 1119 HRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSG 1178
              +S +   P+P+    A      P+      +    PT     +PT T   + TTP   
Sbjct: 357  EPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA----PTTPKEPAPTTTKEPAPTTPKEP 412

Query: 1179 RPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYG 1238
             P  + E A      K+     ++      + P   P+ P  P      E   TT +E  
Sbjct: 413  APTTTKEPA--PTTTKSAPTTPKEPAPTTPKKP--APTTPKEPAPTTPKEPTPTTPKEPA 468

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYM 1298
               +  A  TP        ++   T+                     KE     A +   
Sbjct: 469  PTTKEPAPTTPKEPAPTAPKKPAPTTP--------------------KEP----APTTPK 504

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            +P        +P T+P + A   + S PT++             T      T       +
Sbjct: 505  EPAPTTTKEPSP-TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPT 563

Query: 1359 SPASPSSASKEIGMPFSQGPGTPA-TTAVAPCPAGLPR-GYMTPASPAGSERSPSPSSTA 1416
            +P  P+  + +   P +  P  PA TT   P P    +    TP  PA +    +  +T 
Sbjct: 564  TPKEPAPTTPKKPAPTT--PKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTP 621

Query: 1417 HSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASS 1476
                 +PTT    + T     AP+          E+P   +  E     P  A       
Sbjct: 622  KKL--TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE 679

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA----PASDMPRSPG----APT--- 1525
              P +P  P+ +    P    P+ TA  + +  +P     PA   P+ P     APT   
Sbjct: 680  PAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTK 739

Query: 1526 ---------PSPMVAQGTQ----------TPHRPS--TPRLVWQESSQE-APFMVITLAS 1563
                     P+P   +GT           TP  P+  TP+     + +E AP      A 
Sbjct: 740  EPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799

Query: 1564 DASSQTRMVHASASTSPLCSPT---ETQPTTHGY-SQTTPPSVSQLPPEPPGPPGFPRVP 1619
               + T     +++TS   +PT   ET PTT    + TTP   +   PE P P       
Sbjct: 800  KELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVST 859

Query: 1620 SAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKP 1674
                  P  ++      + + S   +S+ P    +E  P+ PG        A KP
Sbjct: 860  PTTTKEPTTIH-----KSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKP 909



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 138/686 (20%), Positives = 210/686 (30%), Gaps = 68/686 (9%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKP----PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG 70
            P  P    P     P P   +P    P  PA     P A    +   P  P P     P 
Sbjct: 453  PTTPKEPTPTTPKEPAPTTKEPAPTTPKEPA-----PTAPKKPAPTTPKEPAPTTPKEPA 507

Query: 71   PGPGSTSRRLDPKEPL--------GNQRAASPTPKQASATTPGHESPRETRAQGPAGQEA 122
            P          PKEP            +  +PT  +++ TTP   SP  T+   P   + 
Sbjct: 508  PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKE 567

Query: 123  DGPRRTLQVDSRTQR-----SGRSPSVSPDRGSTPT-----SPYSVPQIAPLPSSTLCPI 172
              P    +    T +     + + P+ +  +   PT     +P +  + AP     L P 
Sbjct: 568  PAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPT 627

Query: 173  CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232
                   +TP +P   T      ++       P P   +           + A       
Sbjct: 628  TPEKLAPTTPEKPAPTT----PEELAPTTPEEPTPTTPE-----------EPAPTTPKAA 672

Query: 233  APRSKSQQQLHSPALSPAHSPAKQPL-GKPDQERSRGPGGPQPGSRQAETARATSVPGPA 291
            AP +  +    +P   PA +  K+P    P +     P G  P + +         P P 
Sbjct: 673  APNTPKEPAPTTPK-EPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPK 731

Query: 292  QAA-----APPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGL 346
            + A      P       P P  P   +   P+ PA   P + A   P G   T   +   
Sbjct: 732  ELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP 791

Query: 347  TGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP-KPLGSGPG 405
            T         L    +   +  P + T  +PAP+  TPK       KE  P  P    P 
Sbjct: 792  TTPKKPAPKEL----APTTTKGPTSTTSDKPAPT--TPKETAPTTPKEPAPTTPKKPAPT 845

Query: 406  PGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAIC 465
                P   T   +       P  + K+   ++P+        A + + K   +P  +   
Sbjct: 846  TPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPA 905

Query: 466  PLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSL 525
                             +  TT             T    EKT    +   T ++   + 
Sbjct: 906  ATKPEMTTTAKDKTTERDLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTT 965

Query: 526  GEPTPLP----PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASP 581
             + TP        T+  P V    +   T+ +  K P+   +P     A  S  +T    
Sbjct: 966  QDTTPFKITTLKTTTLAPKVTTTKKTITTTEIMNK-PEETAKPKD--RATNSKATTPKPQ 1022

Query: 582  LPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRR 641
             P+KA    KP    +P   P   + K T  P K   M    PE  PT    +       
Sbjct: 1023 KPTKA--PKKPTSTKKPKTMPRVRKPKTTPTPRK---MTSTMPELNPTSRIAEAMLQTTT 1077

Query: 642  AEPATPVVKAVPEAPKGGEAEDLVGK 667
                TP  K V   PK  +A    G+
Sbjct: 1078 RPNQTPNSKLVEVNPKSEDAGGAEGE 1103



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 148/707 (20%), Positives = 228/707 (32%), Gaps = 83/707 (11%)

Query: 952  PDPSLDREPELEME-SLTGSPEDRSRGEHSSTL--PASTPSYTSGTSPTSLSSLEEDS-- 1006
            P PSL    +   E SLT + E     + ++T     ST      TS     S+E+ S  
Sbjct: 260  PRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319

Query: 1007 DSSPSRRQRLEEAKQQRKARHRSHGPLL-----PTIEDSSEEEELREEEELLREQEKMRE 1061
            D +P+ +     AK   KA   + GP L     PT     E      +E      +    
Sbjct: 320  DLAPTSKVL---AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPT 376

Query: 1062 VEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRS 1121
              ++   +T +      +E      +E + T P   +P     P     ++A       +
Sbjct: 377  TPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPA 436

Query: 1122 SCSEYSPSPSLDSEA------EALDGGPSRLYKSGSE-------YNLPTFMSLYSPTETP 1168
              +   P+P+   E       E     P     +  E          PT     +PT   
Sbjct: 437  PTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPK 496

Query: 1169 SGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFE 1228
              + TTP    P  + E +       A    +          P    S PT P+     E
Sbjct: 497  EPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPK-----E 551

Query: 1229 YQDTTDREYGQAA-QPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKE 1287
               TT +E      +  A  TP        +E   T+    +    ++         K+ 
Sbjct: 552  PSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTP---KEPAPTTTKKPAPTTPKEP 608

Query: 1288 KQFLNAESAYMDPMK------QNGGPLTPG----TSPTQLAAPVSFSTPTSSDSSGGRVI 1337
                  E+A   P K      +   P TP     T+P +LA P +   PT +        
Sbjct: 609  APTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA-PTTPEEPTPTTPEEPAPT 667

Query: 1338 PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGY 1397
                   +  KE         +P +P   +     P    P TP  TA        P   
Sbjct: 668  TPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT--PKETAPTTPKGTAPTTLKEPAPT-- 723

Query: 1398 MTPASPAGSERSPS----PSSTAHSY-------GHSPTTANYGSQT---EDLPQAPSGLA 1443
             TP  PA  E +P+    P+ST           G +PTT    + T   E  P  P G A
Sbjct: 724  -TPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTA 782

Query: 1444 AAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAE 1503
                     P +  +     P P+           P +   P+ + +  P    P+ TA 
Sbjct: 783  ---------PTTLKE-----PAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAP 828

Query: 1504 FSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLA 1562
             + + P+P  P    P +P  P P+        T   P+T      ES+ E        A
Sbjct: 829  TTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888

Query: 1563 SDASSQTRMVHAS---ASTSPLCSPTETQPTTHGYSQTTPPSVSQLP 1606
             + S +   V  +   A+T P  + T    TT    +TTP + +  P
Sbjct: 889  LENSPKEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP 935



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 169/851 (19%), Positives = 268/851 (31%), Gaps = 151/851 (17%)

Query: 1161 LYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTG 1220
            +++PT  PS     P SG     A +  +   +++                   P  P  
Sbjct: 107  VHNPTSPPSSKKAPPPSG-----ASQTIKSTTKRS-------------------PKPPNK 142

Query: 1221 PRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAF 1280
             +     E ++ T+       Q ++  + +S  ++   +I  +  S      A++R+L  
Sbjct: 143  KKTKKVIESEEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNS------AANRELQK 196

Query: 1281 AEDKKKEKQFLNAESAYMDP--MKQNGGPL--------TPGTSPTQ-----------LAA 1319
                K  K+    +     P  + + G  L        TP TS TQ            A 
Sbjct: 197  KLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAK 256

Query: 1320 PVSF--STPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASP--SSASKEIGMPFS 1375
            P++   S P +SD+S    +   + T    KET    K  S+      +SA +   +  +
Sbjct: 257  PINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKT 316

Query: 1376 QGPGTPATTAVAPCPAGLPRGYMTPASPA-GSERSPSPSSTAHSYGHSPTTANYGSQTED 1434
                   T+ V   P   P+   T   PA  + + P+P           TT    + T  
Sbjct: 317  SAKDLAPTSKVLAKPT--PKAETTTKGPALTTPKEPTP-----------TTPKEPASTTP 363

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG 1494
                P+ + +A    +E            P P+       + S P +P  P+ + T  P 
Sbjct: 364  KEPTPTTIKSAPTTPKE------------PAPT------TTKSAPTTPKEPAPTTTKEPA 405

Query: 1495 KMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR--PSTPRLVWQESSQ 1552
               P+  A  +T+ P+P      P +P  P P+        TP    P+TP+     + +
Sbjct: 406  PTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPK 465

Query: 1553 E-APFMVITLASDASSQTRMVHASASTSPL-CSPTETQPTT-HGYSQTTPPSVSQLPPEP 1609
            E AP    T    A +  +    +A   P   +P E  PTT    + TT    S   P+ 
Sbjct: 466  EPAP----TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKE 521

Query: 1610 PGPPGFPRVPSAGAD-GPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDL 1668
            P P      P+   +  P         P E          P T + EP P TP       
Sbjct: 522  PAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAP-- 578

Query: 1669 RTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLAT 1728
             T  +P P    +     T           A  P   +++    P  +     E     T
Sbjct: 579  TTPKEPAPTTPKEPAPTTTKKPAPTTPKEPA--PTTPKETAPTTPKKLTPTTPEKLAPTT 636

Query: 1729 ATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRS 1788
                + T    +     ++P                             E+   T P  +
Sbjct: 637  PEKPAPTTPEELAPTTPEEPT------------------------PTTPEEPAPTTPKAA 672

Query: 1789 GP----RGRPREAKFARYNLPNQVAPLARRDVL-ITQMGTAQSIGLKPGPVPEPGAEPHR 1843
             P       P   K      P + AP   ++    T  GTA +   +P P       P  
Sbjct: 673  APNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 732

Query: 1844 ATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDM 1903
              P   +        KP        +GTA T     P+EPA     T   P         
Sbjct: 733  LAPTTTKEPTSTTCDKPAPTT---PKGTAPTT----PKEPA---PTTPKEPAP------- 775

Query: 1904 VYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRD-PEPPEPPTYRAQGVVG 1962
                P G++ T    PAP+ P+K       P  +  P     D P P  P          
Sbjct: 776  --TTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKE 833

Query: 1963 PGPHEEQRPYP 1973
            P P   ++P P
Sbjct: 834  PAPTTPKKPAP 844



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 138/639 (21%), Positives = 209/639 (32%), Gaps = 122/639 (19%)

Query: 1347 AKETQDPLKLHSSPASPSSA--------------SKEIGMPFSQGPGTP----ATTAVAP 1388
            AKETQ   K  +   +P+S                  +  P    P TP    +TT   P
Sbjct: 307  AKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEP 366

Query: 1389 CPAGLPRGYMTPASPAGSE--------RSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
             P  +     TP  PA +         + P+P++T      +PTT    + T     AP+
Sbjct: 367  TPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP---APTTPKEPAPTTTKEPAPT 423

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
               +A    +E P   +  +     P            P +P  P+ + T  P    P+ 
Sbjct: 424  TTKSAPTTPKE-PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT-TKEPAPTTPKE 481

Query: 1501 TAEFSTQTPSPA-PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVI 1559
             A  + + P+P  P    P +P  P P+      T     P+TP+       + AP    
Sbjct: 482  PAPTAPKKPAPTTPKEPAPTTPKEPAPT------TTKEPSPTTPK-------EPAP---- 524

Query: 1560 TLASDASSQTRMVHASASTSPLCSPTETQP-TTHGYSQTTPPSVSQLPPEPPGPPGFPRV 1618
            T    A + T+    + + S   +P E  P TT   + TTP   +   P+ P P   P+ 
Sbjct: 525  TTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT-TPKE 583

Query: 1619 PSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPII 1678
            P+               P E          P T + EP P TP          + PT   
Sbjct: 584  PAP------------TTPKEPAPTTTKKPAPTTPK-EPAPTTPKETAPTTPKKLTPT--- 627

Query: 1679 LTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMAS 1738
             T + +  T+    A      L P    + T   P                   +   A+
Sbjct: 628  -TPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP--------------EEPAPTTPKAA 672

Query: 1739 SVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAK 1798
            +    ++  P    +P  +         +P   A     E A  T P  + P      A 
Sbjct: 673  APNTPKEPAPTTPKEPAPT---------TPKEPAPTTPKETA-PTTPKGTAPTTLKEPAP 722

Query: 1799 FA-RYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGA 1857
               +   P ++AP   ++   T          KP P    G  P   TP E      P  
Sbjct: 723  TTPKKPAPKELAPTTTKEPTSTTCD-------KPAPTTPKGTAP--TTPKE------PAP 767

Query: 1858 RKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTF 1917
              P        +GTA T      +EPA     T  +P  +    ++      G + T + 
Sbjct: 768  TTPKEPAPTTPKGTAPTTL----KEPA---PTTPKKPAPK----ELAPTTTKGPTSTTSD 816

Query: 1918 HPAPSVPEKSMADAAP--PGQSSSPFYGPRDPEPPEPPT 1954
             PAP+ P K  A   P  P  ++     P  PE P P T
Sbjct: 817  KPAPTTP-KETAPTTPKEPAPTTPKKPAPTTPETPPPTT 854



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 50/201 (24%), Positives = 73/201 (36%), Gaps = 26/201 (12%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSG----GPTQNGFPAHQAPTYPGPST--YPAPAF 3094
            AP TP  PT        P  P+ +A +      PT    PA   P  P P+T    AP  
Sbjct: 649  APTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTT 708

Query: 3095 PPGAS-------YPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQ 3147
            P G +        P  P  P  +   PT      T  PT+ +   P P         P+ 
Sbjct: 709  PKGTAPTTLKEPAPTTPKKPAPKELAPT-----TTKEPTSTTCDKPAPTT-------PKG 756

Query: 3148 TSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVS 3207
            T+    ++  PT  +  A P  P  +AP+      P         ++      G   + S
Sbjct: 757  TAPTTPKEPAPTTPKEPA-PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTS 815

Query: 3208 QSPAPTYPSDSHYTSLEQNVP 3228
              PAPT P ++  T+ ++  P
Sbjct: 816  DKPAPTTPKETAPTTPKEPAP 836



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 49/216 (22%), Positives = 78/216 (36%), Gaps = 15/216 (6%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +K+ S      PA   +
Sbjct: 473  EPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAP-----TTTKEPSPTTPKEPAPTTT 527

Query: 3738 KAEPQA--QPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALT 3795
            K+ P    +P     ++AP   +  SP++ + P+    ++P     ++     P + A T
Sbjct: 528  KSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPT 587

Query: 3796 QAR-----LQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTA 3849
              +       ++  PTT +  AP   +      P   T T P+   P   E+   +    
Sbjct: 588  TPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647

Query: 3850 KAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
             AP     P       P P   KA A    TP  PA
Sbjct: 648  LAPTTPEEPTPTTPEEPAPTTPKAAA--PNTPKEPA 681



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 116/553 (20%), Positives = 190/553 (34%), Gaps = 79/553 (14%)

Query: 2882 SALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKAS-- 2939
            S  PPN   +K K+ + S    E H     Q S    ++S      +  +T+   K+S  
Sbjct: 136  SPKPPNK--KKTKKVIESEEITEEHSVSENQESSSSSSSS------SSSSTIRKIKSSKN 187

Query: 2940 --LLRELDRDLRLVEHESTKLRKKQAE----LDEEEKEIDA---KLKYLELGITQRKE-- 2988
                REL + L++ +++  + +KK       +DE    +D    K+   +   TQ  +  
Sbjct: 188  SAANRELQKKLKVKDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVS 247

Query: 2989 SLAKDRGGRDYPPLRGLGEHRDYLSDSELN-----------------QLRLQGC--TTPA 3029
            +  K    +   P   L  + D   ++ L                  Q    G   TT A
Sbjct: 248  TSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSA 307

Query: 3030 GQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTY 3089
             +      T+A    P+     +      P P+    + GP     P    PT P     
Sbjct: 308  KETQSIEKTSAKDLAPTSKVLAK------PTPKAETTTKGPALTT-PKEPTPTTPKEPAS 360

Query: 3090 PAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQT----PMPTTQSTLFPVPADSRAPLQKP 3145
              P  P   +  + P  P + A  PT   +  T    P PTT  T  P P   + P    
Sbjct: 361  TTPKEPTPTTIKSAPTTPKEPA--PTTTKSAPTTPKEPAPTT--TKEPAPTTPKEPAPTT 416

Query: 3146 RQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGS 3205
             +       +  PT  +  A P  P   AP  T+   PA ++  E    P  P+  +   
Sbjct: 417  TKEPAPTTTKSAPTTPKEPA-PTTPKKPAP--TTPKEPAPTTPKE--PTPTTPK--EPAP 469

Query: 3206 VSQSPAPTYPSDSHYTSLEQNVPRN------YVMIDDISELTKDSTSTAPDSQRLEPLGP 3259
             ++ PAPT P +   T+ ++  P            +     TK+ + T P  +   P   
Sbjct: 470  TTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTP--KEPAPTTT 527

Query: 3260 GSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPAST-- 3317
             S+    KEP        PT P      +E S   + +P        +  +  +PA T  
Sbjct: 528  KSAPTTTKEPAPTTTKSAPTTP------KEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTP 581

Query: 3318 HYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEE 3377
                 +  +  A      P P  PK P+ +  P   +    K       +K++  +P + 
Sbjct: 582  KEPAPTTPKEPAPTTTKKPAPTTPKEPAPT-TPKETAPTTPKKLTPTTPEKLAPTTPEKP 640

Query: 3378 AKDVESDLASYPP 3390
            A     +LA   P
Sbjct: 641  APTTPEELAPTTP 653



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 130/638 (20%), Positives = 213/638 (33%), Gaps = 90/638 (14%)

Query: 952  PDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPS 1011
            P P+  +EP     + T  P   +  E + T   S P+ T   +PT+  S    +   PS
Sbjct: 498  PAPTTPKEPA---PTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT-TPKEPS 553

Query: 1012 RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTA 1071
                 E A               PT          ++      ++      ++    +T 
Sbjct: 554  PTTTKEPA---------------PTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTK 598

Query: 1072 RKTRRDKEELRAQRRRERSKTPPSNLSPI--EDASPTEELRQAAEM-EELHRSSCSEYSP 1128
            +      +E      +E + T P  L+P   E  +PT   + A    EEL  ++  E +P
Sbjct: 599  KPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTP 658

Query: 1129 S----PSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSA 1184
            +    P+  +   A    P     +  +   PT     +PT     + TTP    P    
Sbjct: 659  TTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLK 718

Query: 1185 EEAYEEMMRKA--ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE------ 1236
            E A     + A  EL      +          P+ P G       E   TT +E      
Sbjct: 719  EPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTP 778

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESA 1296
             G A     E  P +      +E+  T+    +   +++ D       K+       E A
Sbjct: 779  KGTAPTTLKEPAPTTPKKPAPKELAPTT---TKGPTSTTSDKPAPTTPKETAPTTPKEPA 835

Query: 1297 YMDPMKQNGGPLTPGTSP---TQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
               P K    P TP T P   ++++ P +   PT+   S     PD    +  A+ T  P
Sbjct: 836  PTTPKKP--APTTPETPPPTTSEVSTPTTTKEPTTIHKS-----PDESTPELSAEPT--P 886

Query: 1354 LKLHSSPASPSSASKEIGMPFSQGPG---------------------TPATTAVAPCPAG 1392
              L +SP       KE G+P ++ P                      TP TT  AP    
Sbjct: 887  KALENSP-------KEPGVPTTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAP---- 935

Query: 1393 LPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREK 1452
                 MT  +   +E++     TA +   + TT    +  +      + LA      ++ 
Sbjct: 936  ----KMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKT 991

Query: 1453 PLSA---SDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG-KMGPRATAEFSTQT 1508
              +    +  E       RA +  A++  P  P+   + PT +   K  PR     +T T
Sbjct: 992  ITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPKTMPRVRKPKTTPT 1051

Query: 1509 PSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLV 1546
            P     S MP        +  + Q T  P++    +LV
Sbjct: 1052 PRKM-TSTMPELNPTSRIAEAMLQTTTRPNQTPNSKLV 1088



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 51/242 (21%), Positives = 85/242 (35%), Gaps = 18/242 (7%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSS-AEYSQPSRASSAYH 3716
            T +EP   A K  A    +  A P +    AP   K+  P  P   A  +  S  ++   
Sbjct: 478  TPKEPAPTAPKKPAPTTPKEPA-PTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQP 3776
             A  + K +      P+   +K      P    ++ AP   +  +P++ + P+    ++P
Sbjct: 537  PAPTTTKSAPTTPKEPSPTTTKEPAPTTP----KEPAPTTPKKPAPTTPKEPAPTTPKEP 592

Query: 3777 QTQQQQQGLGLQPPQQALTQARLQQQSQPTT----RGSAPAASQPAGKPQPGPSTA---- 3828
                 ++     P + A T  +   ++ PTT      + P    P    +P P+T     
Sbjct: 593  APTTTKKPAPTTPKEPAPTTPK---ETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELA 649

Query: 3829 -TGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQ 3887
             T P+   P   E+   +   A AP   + P       P P   K  A       AP   
Sbjct: 650  PTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTP 709

Query: 3888 PG 3889
             G
Sbjct: 710  KG 711



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 49/211 (23%), Positives = 66/211 (31%), Gaps = 8/211 (3%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+   P  P      T  E  PSP    +  P   +        P+  T ++A  
Sbjct: 490  PAPTTPKEPAPTTPKEPAPTTTKE--PSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPT 547

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPM-IAPRV 2251
                   T      P T +  +   P           +      P  + T+ P    P+ 
Sbjct: 548  TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKE 607

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T     P   +  +  + P    P    KPA    P    P+ PE P     EEP 
Sbjct: 608  PAPTTPKETAPTTPK-KLTPTTPEKLAPTTPEKPAPT-TPEELAPTTPEEPTPTTPEEPA 665

Query: 2312 PTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            PTT  AA       PAP      K PA   P
Sbjct: 666  PTTPKAAAPNTPKEPAPTT---PKEPAPTTP 693



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 56/230 (24%), Positives = 73/230 (31%), Gaps = 23/230 (10%)

Query: 2132 GPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAAD 2191
            GP L+ P+   P  P    + T  E  P+    A   P     T  +   P+T    A  
Sbjct: 341  GPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSA-PTTPKEPAPT 399

Query: 2192 GMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV 2251
                    TP       T +PA             P  +      P T     P   P+ 
Sbjct: 400  TTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPT-TPKE 458

Query: 2252 PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPL 2311
            P   T   + PAP+    A + P    P    KPA         P+ P+ P     +EP 
Sbjct: 459  PTPTTP--KEPAPTTKEPAPTTPKEPAPTAPKKPA---------PTTPKEPAPTTPKEPA 507

Query: 2312 PTTT----PAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
            PTTT    P   KE      PAP   +  P        +   S P   KE
Sbjct: 508  PTTTKEPSPTTPKE------PAPTTTKSAPTTTKEPAPTTTKSAPTTPKE 551



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 44/238 (18%), Positives = 78/238 (32%), Gaps = 16/238 (6%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            T +EP     K  A    +  A P +   +AP  PKK  P  P     + P + +     
Sbjct: 588  TPKEPAPTTTKKPAPTTPKEPA-PTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPE 646

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQ-- 3775
                        + P    +   P+A      ++ AP   +  +P++ + P+    ++  
Sbjct: 647  ELAPTTPEEPTPTTPEE-PAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETA 705

Query: 3776 PQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRG------------SAPAASQPAGKPQP 3823
            P T +      L+ P     +    ++  PTT              + P  + P    +P
Sbjct: 706  PTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEP 765

Query: 3824 GPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTP 3881
             P+T   P P  P     T   +     P++    +  P    GP    +      TP
Sbjct: 766  APTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 59/235 (25%), Positives = 79/235 (33%), Gaps = 19/235 (8%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  + P+ L P  P     PT PE  P+P       P A      ++  P+T    A   
Sbjct: 640  PAPTTPEELAPTTPEE-PTPTTPE-EPAPTT-----PKAAAPNTPKEPAPTTPKEPAPTT 692

Query: 2193 MIYSTINTP--IAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPR 2250
                   TP   A T P  T P ++  P               T     + T     AP 
Sbjct: 693  PKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752

Query: 2251 VPLG--PTGLYRYPAPS--RFPIASSVPPAEGPVYLGKPAAAK----APGAGGPSRPEMP 2302
             P G  PT   + PAP+  + P A + P    P  L +PA       AP    P+  + P
Sbjct: 753  TPKGTAPT-TPKEPAPTTPKEP-APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGP 810

Query: 2303 VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKE 2357
                 ++P PTT           PAP       P     P   +  +S P   KE
Sbjct: 811  TSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKE 865



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 50/168 (29%), Positives = 63/168 (37%), Gaps = 27/168 (16%)

Query: 3026 TTPAGQFVDFPATAA-------APATPSG--PTAFQQPRF---QPPAPQYSAGSGGPTQN 3073
            TTP G     P   A       AP TP G  PT  ++P     + PAP+  A    PT  
Sbjct: 752  TTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELA----PTTT 807

Query: 3074 GFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFP 3133
              P       P P+T P    P     PA P  P + A  PT     +TP PTT     P
Sbjct: 808  KGPTSTTSDKPAPTT-PKETAPTTPKEPA-PTTPKKPA--PT---TPETPPPTTSEVSTP 860

Query: 3134 VPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV---VPMSSAPSET 3178
                    + K    S  +L  + PT   +  SP    VP +  P+ T
Sbjct: 861  TTTKEPTTIHKSPDESTPELSAE-PTPKALENSPKEPGVPTTKTPAAT 907



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 52/216 (24%), Positives = 73/216 (33%), Gaps = 28/216 (12%)

Query: 2138 PQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTA---VRQLLPSTATVRAADGMI 2194
            P    P  P     PT P+  P+P    +  P   +GTA   +++  P+T    A   + 
Sbjct: 680  PAPTTPKEPA----PTTPK-EPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734

Query: 2195 YSTINTPIAATL--PITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
             +T   P + T   P  T P        +            T    T+ T +   AP  P
Sbjct: 735  PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 794

Query: 2253 LGPTGLYRYPAPSRFPIA--SSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEP 2310
              P      P  ++ P +  S  P    P    K  A   P    P+ P+ P     E P
Sbjct: 795  KKPAPKELAPTTTKGPTSTTSDKPAPTTP----KETAPTTPKEPAPTTPKKPAPTTPETP 850

Query: 2311 LPTT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
             PTT    TP   KE        P    K P ++ P
Sbjct: 851  PPTTSEVSTPTTTKE--------PTTIHKSPDESTP 878



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 34/178 (19%), Positives = 62/178 (34%), Gaps = 11/178 (6%)

Query: 3687 SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQ 3746
            SAP  PK+  P    SA  +    A +       +K+ +      PA   +K     +P 
Sbjct: 373  SAPTTPKEPAPTTTKSAPTTPKEPAPTT------TKEPAPTTPKEPAPTTTK-----EPA 421

Query: 3747 LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT 3806
                ++AP   +  +P++ + P+    ++P     ++     P + A T       +   
Sbjct: 422  PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKE 481

Query: 3807 TRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAP 3864
               +AP    P    +P P+T   P P        T   +      +       +PAP
Sbjct: 482  PAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAP 539



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 45/236 (19%), Positives = 71/236 (30%), Gaps = 30/236 (12%)

Query: 3678 EARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            E  P +    AP  PKK  P  P     + P   +      + +KK +      PA    
Sbjct: 559  EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAP-----TTTKKPAPTTPKEPAPTTP 613

Query: 3738 KAEPQAQPQ------------LQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGL 3785
            K      P+                + AP   +  +P++ + P+     +P     +   
Sbjct: 614  KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673

Query: 3786 GLQPPQQALTQARLQQQSQPTTRG-SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +    + P     + P  + P       P+T   P P  P +      
Sbjct: 674  PNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733

Query: 3845 SKGTAKAP------------QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            +  T K P             +G AP     P P      A   P GT      +P
Sbjct: 734  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEP 789



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 37/121 (30%), Positives = 48/121 (39%), Gaps = 18/121 (14%)

Query: 2239 TSLTRVPMIAPRVP--LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGP 2296
            T+ T    + P  P  L PT   + PAP+     +   P E      +  A   P A  P
Sbjct: 616  TAPTTPKKLTPTTPEKLAPTTPEK-PAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAP 674

Query: 2297 SRPEMPVGAAREEPLPTT----TPAAIKEAA------GAPA----PAPLAGQKP-PADAA 2341
            + P+ P     +EP PTT     P   KE A       AP     PAP   +KP P + A
Sbjct: 675  NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734

Query: 2342 P 2342
            P
Sbjct: 735  P 735



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 48/244 (19%), Positives = 81/244 (33%), Gaps = 31/244 (12%)

Query: 3657 HTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYH 3716
            +T +EP     K  A    +  A P +   +AP  PK   P        + P + +    
Sbjct: 675  NTPKEPAPTTPKEPAPTTPKEPA-PTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKEL 733

Query: 3717 HASDSKKGSRQAHSGPAALQSKAEPQAQPQLQG----RQAAPGPQQSQSPSSRQIPSGAA 3772
              + +K+ +      PA    K      P+       ++ AP   +  +P++ + P+   
Sbjct: 734  APTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTT 793

Query: 3773 SRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQ 3832
             ++P  ++      L P       +    +  PTT    P  + P    +P P+T   P 
Sbjct: 794  PKKPAPKE------LAPTTTKGPTSTTSDKPAPTT----PKETAPTTPKEPAPTTPKKPA 843

Query: 3833 PAGPPRAEQTNGSKGTA----------KAPQQGRAP-QAQPAP-----GPGPAGVKAGAR 3876
            P  P     T     T           K+P +      A+P P      P   GV     
Sbjct: 844  PTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKT 903

Query: 3877 PGGT 3880
            P  T
Sbjct: 904  PAAT 907



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 52/214 (24%), Positives = 70/214 (32%), Gaps = 17/214 (7%)

Query: 2133 PGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADG 2192
            P  +AP+   P  P     PT P+  P+P    +  P     T  ++  P+T        
Sbjct: 482  PAPTAPKKPAPTTPKEPA-PTTPK-EPAPTTTKEPSP-----TTPKEPAPTTTKSAPTTT 534

Query: 2193 MIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVP 2252
               +   T  A T P    P +   P        P  +      P T     P   P+ P
Sbjct: 535  KEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK-EPAPTTPKKPAPTTPKEPAPT-TPKEP 592

Query: 2253 LGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLP 2312
               T   + PAP+     +   P E      K      P    P+ PE P     EE  P
Sbjct: 593  APTTT--KKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAP 650

Query: 2313 TT----TPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            TT    TP   +E   AP     A    P + AP
Sbjct: 651  TTPEEPTPTTPEEP--APTTPKAAAPNTPKEPAP 682



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 41/212 (19%), Positives = 78/212 (36%), Gaps = 20/212 (9%)

Query: 3682 HSQPSSAP----AMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK----GSRQAHSGPA 3733
            H++ S++P    A P   +P  P +++ S+ +  +       ++K+      + +  G  
Sbjct: 243  HNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKE 302

Query: 3734 ALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSR-----QIPSGAASRQPQTQQQQQGLGLQ 3788
               S  E Q+  +   +  AP  +    P+ +     + P+    ++P     ++     
Sbjct: 303  KTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTT 362

Query: 3789 PPQQALTQAR----LQQQSQPTTRGSAPAA-SQPAGKPQPGPSTATGPQPAGPPRAEQTN 3843
            P +   T  +      ++  PTT  SAP    +PA      P+  T  +PA  P   +  
Sbjct: 363  PKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPA--PTTTKEP 420

Query: 3844 GSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGA 3875
                T  AP   + P       P P   K  A
Sbjct: 421  APTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA 452



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 46/210 (21%), Positives = 65/210 (30%), Gaps = 8/210 (3%)

Query: 2152 PTFPEGHPSPGNLAQYGPAAGQG--TAVRQLLPSTATVRAADGMIYSTINTPIAATLPIT 2209
            PT P+  P+P    +  P   +   T  ++  P+T    A          TP   T    
Sbjct: 406  PTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP 464

Query: 2210 TQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPI 2269
             +PA   +         P  +      P T     P   P+ P   T     P   + P 
Sbjct: 465  KEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPT-TPKEPAPTTTKEPSPTTPKEPA 523

Query: 2270 ASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPA 2329
             ++   A  P    +PA      A  P+ P+ P     +EP PTT           PAP 
Sbjct: 524  PTTTKSA--PTTTKEPAPTTTKSA--PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPT 579

Query: 2330 PLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
                  P     P   +     P   KE A
Sbjct: 580  TPKEPAPTTPKEPAPTTTKKPAPTTPKEPA 609



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 37/209 (17%), Positives = 69/209 (33%), Gaps = 6/209 (2%)

Query: 3667 AKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            +K  A+   + E        + P  P    P  P+S    +P+  +      +  +    
Sbjct: 325  SKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPT 384

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS-RQPQTQQQQQGL 3785
               S P   +  A    +         P P  ++ P+     S   + ++P     ++  
Sbjct: 385  TTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPA 444

Query: 3786 GLQPPQQALTQARLQQQSQPTT-RGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
               P + A T  +   +  PTT +  AP   +PA      P+  T P+   P   ++   
Sbjct: 445  PTTPKEPAPTTPK---EPTPTTPKEPAPTTKEPAPTTPKEPAP-TAPKKPAPTTPKEPAP 500

Query: 3845 SKGTAKAPQQGRAPQAQPAPGPGPAGVKA 3873
            +     AP   + P       P P   K+
Sbjct: 501  TTPKEPAPTTTKEPSPTTPKEPAPTTTKS 529


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 87.4 bits (215), Expect = 2e-16
 Identities = 189/776 (24%), Positives = 258/776 (33%), Gaps = 106/776 (13%)

Query: 17   PPG---GAGPGPGPGPG--PGAGKPPSAPAGGGQLPAAGAARSTAVPPV-PGPGPGPGPG 70
            PPG    A P PGP P   P +    ++PAG   +PA+       +PP+ P  G  P   
Sbjct: 1027 PPGPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLLPPLQPNSGSLPQVL 1086

Query: 71   PGP-GSTSRRLDPKEPLGNQRAASPTPKQAS-ATTPGHESPRETRAQGPAGQEADGPRRT 128
            P P G  S    P  P  + +   P P + S A  PG  S  +     P          T
Sbjct: 1087 PSPLGVLSGTSRPPTPTLSLKPTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATT 1146

Query: 129  LQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFN 188
                + T  +   P+ +P       SP      A LPS  +  I + + L   P      
Sbjct: 1147 TSTTTATATTTAVPAPTPAPQRLILSP---DMQARLPSGEVVSIGQLASLAQRP------ 1197

Query: 189  TCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM-QRALGMDMTTAPRSKSQQQLHSPAL 247
                    V N  G  P     Q  +      Q+ Q A+G      PR   +  +H  + 
Sbjct: 1198 --------VANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQ-----PRPLQRNVVHLVSA 1244

Query: 248  SPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPP 307
               H    QP      +      GP P S    +  +T+ P P   + P    +V P   
Sbjct: 1245 GGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTT-PAPTGLSLPLAANQVPPTMV 1303

Query: 308  QPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSV 367
                 +T   +    +AP    T VP    A      GL         ++L    TL   
Sbjct: 1304 N----NTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGL--------PAVLNPRPTLTPG 1351

Query: 368  QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTE----PGARMGPG 423
            +    T G       TP +V         P P  S   PG AP   +     P +  GP 
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411

Query: 424  SGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPL---CQAELNVGSKSPA 480
            S P  +P +    SP         +S       T     A  PL     A L V +  PA
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471

Query: 481  NYNTCTTCRLQVCNLCGFNPT---PHLVEKTEWLCLNCQTKRLLEGSL--GEPTPLPPPT 535
               + T     V       P+            L L   T   L  S   G P  L P +
Sbjct: 1472 LLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS 1531

Query: 536  SQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRA 595
            S  P + +   A   SP+             P  A ASP  +  +P P++AS  A    A
Sbjct: 1532 SHVPGLNST-VAPACSPVLV-----------PASALASPFPSAPNPAPAQASLLAPASSA 1579

Query: 596  SEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPA-TPKVKSGVRRAEPATPVVKAVPE 654
            S+   TP +        P  A   P P P   P P   P   +    A   TPV    P 
Sbjct: 1580 SQALATPLA----PMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPS 1635

Query: 655  APKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVT 714
            +  G           +  AS SP        +    SS+Q+ +   V             
Sbjct: 1636 STPG-----------TSLASASPVPAPTPVLAP---SSTQTMLPAPV------------- 1668

Query: 715  GPHP-PSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRP-HSLSITP 768
             P P PSP+    +  ++ P L A  L  S  S+ LS GTG  Q   P  +LS+TP
Sbjct: 1669 -PSPLPSPASTQTL--ALAPAL-APTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTP 1720



 Score = 76.3 bits (186), Expect = 6e-13
 Identities = 188/832 (22%), Positives = 275/832 (33%), Gaps = 124/832 (14%)

Query: 15   PLPPGGAGPGPGPGPGPGAG-KPPSAPAGGGQLPAAGAARSTAVPP-----VPGPGPGPG 68
            P PP      P P PG  +  KP + P G    PAA    ST         VP P P P 
Sbjct: 1108 PTPPAPVRLSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQ 1167

Query: 69   PGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQG--------PAGQ 120
                      RL   E +   + AS    Q      G   P   + QG           Q
Sbjct: 1168 RLILSPDMQARLPSGEVVSIGQLASLA--QRPVANAGGSKPLTFQIQGNKLTLTGAQVRQ 1225

Query: 121  EADGPRRTLQVD--------------SRTQRSGRSPSVSPDRGSTPTS--PYSVPQIAPL 164
             A G  R LQ +              S+        +V+P  G TP S  P S P   P 
Sbjct: 1226 LAVGQPRPLQRNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPA 1285

Query: 165  PSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQR 224
            P+    P+         P+  N     +   +   + G  P P L               
Sbjct: 1286 PTGLSLPLAANQ---VPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPR--------PP 1334

Query: 225  ALGMDMTTAPR-SKSQQQLHSPALSPAHSPAKQP---------LGKPDQERSRGPGGPQP 274
            + G+     PR + +  +L +P L  A +P   P         +  P  E S    G  P
Sbjct: 1335 SSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAP 1394

Query: 275  GSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPA 334
             +  +     +S+PGPA +  P     +    P  +  S+    P +   P    T +PA
Sbjct: 1395 LTISSPLHVPSSLPGPASSPMP-----IPNSSPLASPVSSTVSVPLSSSLPISVPTTLPA 1449

Query: 335  GLGATEQTQEGLTGKLFGLGASLLTQAST-LMSVQPEADTQGQPAPSKGTPKIVFNDASK 393
               A           +   G +LLT  +  L  V P A      APS  +P         
Sbjct: 1450 PASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSASALTLGL 1509

Query: 394  EAGPKPLGSGPGPGP----APGAKTEPG--ARMGPGSGPGALPKTG------GTTSPKHG 441
               P  L S   PG     AP +   PG  + + P   P  +P +          +P   
Sbjct: 1510 ATAPS-LSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPA 1568

Query: 442  RAEHQAASKAAAK-------PKTMPKERAICPLCQ---AELNVGSKSPANYNTCTTCRLQ 491
            +A   A + +A++       P   P+   + P      A L V + SP       + +  
Sbjct: 1569 QASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVLASSQTP 1628

Query: 492  V----------CNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPV 541
            V           +L   +P P        +     T+ +L   +  P+PLP P S Q   
Sbjct: 1629 VPVMAPSSTPGTSLASASPVPAPTP----VLAPSSTQTMLPAPV--PSPLPSPASTQTLA 1682

Query: 542  GAPHRA---SGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEP 598
             AP  A    G+SP  Q    G G P GP P +   L+  +S +P+ A  Q   L    P
Sbjct: 1683 LAPALAPTLGGSSP-SQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPA--QTLSLAPGPP 1739

Query: 599  SKTPSSVQEKKTRVPTKAEPM-PKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPK 657
                 ++          A P+ P P    T  PA+    S      PA+     +  AP 
Sbjct: 1740 LGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPAS----SSASLLAPASVQTLTLSPAP- 1794

Query: 658  GGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQS-----EITGVVQQEVEQLDSAG 712
                   +G   +Q  + +P S       +  +  S S      +T V +  V + +   
Sbjct: 1795 ----VPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDT 1850

Query: 713  VT-GPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHS 763
            +T    PPSP          RP  Q     P     P    + EE+++R  S
Sbjct: 1851 LTLRSGPPSPPSTATSFGGPRPRRQ----PPPPPRSPFYLDSLEEKRKRQRS 1898



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 80/338 (23%), Positives = 130/338 (38%), Gaps = 45/338 (13%)

Query: 1307 PLTPGTSPTQ--LAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLK-LHSSP-AS 1362
            P  P  +P Q  L AP S ++   +        P   +          PL  L  SP A+
Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAA 1619

Query: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHS 1422
            P  AS +  +P      TP T+  +  P   P   + P+S      +P PS         
Sbjct: 1620 PVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPL------- 1672

Query: 1423 PTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSP 1482
            P+ A+    T+ L  AP+     G ++  + LS   G    P P++  S   +SS  L P
Sbjct: 1673 PSPAS----TQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASS--LVP 1726

Query: 1483 SSPSESPTFSPG-KMGPRATAEFSTQTP-------SPAPASDMPRSPGAPTPSPMVAQGT 1534
             +P+++ + +PG  +GP  T   +   P        PAPA  +  +P + + S +     
Sbjct: 1727 -TPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASV 1785

Query: 1535 QT-PHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPL---------CSP 1584
            QT    P+    +   ++Q       +  S AS  + +V +++  +PL          S 
Sbjct: 1786 QTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSK 1845

Query: 1585 TETQPTTHGYSQTTPPSVS---------QLPPEPPGPP 1613
             E    T      +PPS +         + PP PP  P
Sbjct: 1846 DEPDTLTLRSGPPSPPSTATSFGGPRPRRQPPPPPRSP 1883



 Score = 58.5 bits (140), Expect = 1e-07
 Identities = 154/690 (22%), Positives = 236/690 (34%), Gaps = 132/690 (19%)

Query: 1310 PGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKE 1369
            P ++P+   AP   S P +++     ++ +  V +   ++          P +P+     
Sbjct: 1276 PSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPS 1335

Query: 1370 IGMPFSQGPGTPATTAVAPCPA-GLPRGYM-TPASPAGSER---SPSPSSTAHSYGHSPT 1424
             G+P    P    T    P P  G  R  M TP       +   SPSP  +A + G +P 
Sbjct: 1336 SGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPL 1395

Query: 1425 TANYGSQTEDLPQAPSGLAAAGRAA-REKPLSASDGEGGTPQPSRAYSYFASSSPPLSPS 1483
            T    S    +P +  G A++        PL++      +   S +      ++ P   S
Sbjct: 1396 TI---SSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPAS 1452

Query: 1484 SPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQ----------- 1532
            +P   P  +P  +     A  ++ TP  AP   +P +PG P+ +P  A            
Sbjct: 1453 APLTIPISAPLTVSASGPALLTSVTPPLAPV--VPAAPGPPSLAPSGASPSASALTLGLA 1510

Query: 1533 ------GTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTE 1586
                   +QTP  P    L+   +S   P +  T+A   S    +V ASA  SP   P+ 
Sbjct: 1511 TAPSLSSSQTPGHP----LLLAPTSSHVPGLNSTVAPACSPV--LVPASALASPF--PSA 1562

Query: 1587 TQPTTHGYSQTTPPS-VSQLPPEPPGPPGFPRV----PSAG---ADGPLALYGWGALPAE 1638
              P     S   P S  SQ    P  P   P+     PS     A  P+     GA P  
Sbjct: 1563 PNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPAPPLAPLPVLAPSPGAAPVL 1622

Query: 1639 NISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGL 1698
              S   +  +  +S       TPGT++        PTP++       +    V +     
Sbjct: 1623 ASSQTPVPVMAPSS-------TPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPS----- 1670

Query: 1699 ALDPIPGRQST-------AVQPLVINLNAQEHTFLATAT--------TVSITMASSVFMA 1743
               P+P   ST       A+ P +   +  +   L T          T+S+T ASS+   
Sbjct: 1671 ---PLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPT 1727

Query: 1744 QQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFARYN 1803
                      P Q+        G P+   Q   +  A   AP  + P G P  A      
Sbjct: 1728 ----------PAQT---LSLAPGPPLGPTQTLSLAPAPPLAP--ASPVG-PAPAHTLT-- 1769

Query: 1804 LPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTV 1863
                +AP +    L+    + Q++ L P PVP  G    +       S   P ++    V
Sbjct: 1770 ----LAPASSSASLLAP-ASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLV 1824

Query: 1864 VVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSV 1923
            V   G               A  L +T            MV +LP       T       
Sbjct: 1825 VSASG---------------AAPLPVT------------MVSRLPVSKDEPDTLTLRSGP 1857

Query: 1924 PEKSMADAAPPGQSSSPFYGPRDPEPPEPP 1953
            P       +PP  ++S F GPR    P PP
Sbjct: 1858 P-------SPPSTATS-FGGPRPRRQPPPP 1879



 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 126/537 (23%), Positives = 180/537 (33%), Gaps = 72/537 (13%)

Query: 1463 TPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGP--------------RATAEFSTQT 1508
            TP P+   S   SS+P  +P+    S   +  ++ P              +A  +  T  
Sbjct: 1266 TPGPTPV-SVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPV 1324

Query: 1509 PSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQ 1568
            P  APA   PR P +  P+ +  + T TP R  TP L    +    P +V  L     S 
Sbjct: 1325 PPLAPA---PRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSP 1381

Query: 1569 TRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFP-----RVPSAGA 1623
            +  V ASA   P  +P       H  S    P+ S +P     P   P      VP   +
Sbjct: 1382 SPEVSASA---PGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVP-LSS 1437

Query: 1624 DGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQG 1683
              P+++      PA       IS+    S   P   T  T  +       P P  L   G
Sbjct: 1438 SLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSG 1497

Query: 1684 MDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQE----HTFLATATTVSITMASS 1739
                S +  A   GLA  P      T   PL++   +      ++ +A A +  +  AS+
Sbjct: 1498 ---ASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAPACSPVLVPASA 1554

Query: 1740 VFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKF 1799
            +             P+ S  +      S   LA      QA+ T      P   P+ A  
Sbjct: 1555 L-----------ASPFPSAPNPAPAQAS--LLAPASSASQALATP---LAPMAAPQTAIL 1598

Query: 1800 ARYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVP------EPGAEPHRATPAELRSHA 1853
            A    P+   PLA   VL    G A  +     PVP       PG     A+P    +  
Sbjct: 1599 A----PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPV 1654

Query: 1854 L-PGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSS 1912
            L P + +            +   T  L   PA A  L G  P   L+      + PF + 
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQ 1714

Query: 1913 CTGTFHPAPSVPEK----SMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQGVVGPGP 1965
                   +  VP      S+A   P G + +    P  P  P  P       VGP P
Sbjct: 1715 TLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASP-------VGPAP 1764



 Score = 52.8 bits (125), Expect = 7e-06
 Identities = 199/871 (22%), Positives = 272/871 (31%), Gaps = 182/871 (20%)

Query: 61   PGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHE-----SPRETRAQ 115
            PG G     G G G+  R    K P       S   + A A T G       S  +TR+ 
Sbjct: 2364 PGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGARAETQGANHTPVISAHQTRS- 2422

Query: 116  GPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKT 175
                     P R      R  R    P  +P      ++P ++P + P+P S   PI   
Sbjct: 2423 ------TTTPPRCSPARERVPRPAPRPRPTP-----ASAPAAIPALVPVPVSAPVPISAP 2471

Query: 176  SDLT-----STPSQPNFNTCTQCHNKVCN-QCGFNPNPHLTQVKEWLCLNCQMQRALGMD 229
            + +T       PS P  +    C +  C       P P  T      CL       L + 
Sbjct: 2472 NPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLL-LG 2530

Query: 230  MTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPG 289
              + P S S   L    L P      Q L  P+                +ET+  + VP 
Sbjct: 2531 PPSVPISASVTNL-PLGLRPEAELCAQALASPESLELASVA-------SSETSSLSLVPP 2582

Query: 290  PAQAAAPPEVGRVS-------PQPPQPTKPSTAEPRPPAGEAP----AKSATAVPAG--- 335
                    E+  VS       P  P  T  + + P     EAP      + T +P G   
Sbjct: 2583 KDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEEL 2642

Query: 336  ---------------LGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPS 380
                             + E  QE L        +  LT+A T  S  PE   Q      
Sbjct: 2643 PLCVSESNGLELPPSAASDEPLQEPLEA---DRTSEELTEAKTPTS-SPE-KPQELVTAE 2697

Query: 381  KGTPKIVFNDASKEAGPKPL--------------GSGPG-PGPAPGAKT----------- 414
               P    +  S   GP P               G G G PG  PG K            
Sbjct: 2698 VAAPSTSSSATSSPEGPSPARPPRRRTSADVEIRGQGTGRPGQPPGPKVLRKLPGRLVTV 2757

Query: 415  --------------------EPG---ARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKA 451
                                 PG       PGS P     +G  +SP  G     A S +
Sbjct: 2758 VEEKELVRRRRQQRGAASTLVPGVSETSASPGS-PSVRSMSGPESSPPIGGPCEAAPSSS 2816

Query: 452  AAKPKTMPKERAICPLCQAELNV-GSKSPANYNTCTTCRL--QVCNLCGFNPTPHLVEKT 508
               P   P           EL V G  SP N +          V    G  P  +     
Sbjct: 2817 LPTPPQQP----FIARRHIELGVTGGGSPENGDGALLAITPPAVKRRRGRPPKKNRSPAD 2872

Query: 509  EWLCLNCQTKRLLEGSLGEPTPLPPPTS--QQPPVGAPHRASGTSPLKQKGPQGLGQPSG 566
                ++      L+G      P+P P +     PV  P    G  PL   GPQ + +P+ 
Sbjct: 2873 AGRGVDEAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQPL---GPQPVHRPN- 2928

Query: 567  PLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPM-PKPPPE 625
            PL    SP+  +    P KA     P   S      S   E +T+ P    P+ P PP  
Sbjct: 2929 PL---LSPVEKRRRGRPPKARDLPIPGTISSAGDGNS---ESRTQPPPHPSPLTPLPPLL 2982

Query: 626  TTPT-------------PATPKVKSGVRRAEPATPVVKAVP------------------E 654
              PT              + PK K G     P +P    +P                   
Sbjct: 2983 VCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPVLDRDSTSVLESCGLGRRR 3042

Query: 655  APKG-GEAEDLVGKPYSQDASRSPQSLSDTGYSSDGI---SSSQSEITGVVQQEVEQLDS 710
             P+G GE+E   G    +D SR    L+     ++G+    S  S +  V+Q +++  DS
Sbjct: 3043 QPQGQGESE---GSSSDEDGSRPLTRLARLRLEAEGMRGRKSGGSMVVAVIQDDLDLADS 3099

Query: 711  A-GVTGPHPPSPSEIHKVGS------SMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHS 763
              G     PP  S   K+ S      S+ P L+ + L       P+    G  ++ R   
Sbjct: 3100 GPGGLELTPPVVSLTPKLRSTRLRPGSLVPPLETEKLPRKRAGAPVGGSPGLAKRGRLQP 3159

Query: 764  LS-ITPEAFDSDEELEDILEEDEDSAEWRRR 793
             S + PE    + E E   EE+E     RRR
Sbjct: 3160 PSPLGPEGSVEESEAEASGEEEEGDGTPRRR 3190



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 89/357 (24%), Positives = 123/357 (34%), Gaps = 58/357 (16%)

Query: 1377 GPGTPATTAVAPCPAGLPRGYMTPASPAG-----SERSPSPSSTAHSYGHSPTTANYGSQ 1431
            GP   A     P P  LP   M  ASPAG     + R P P          P   N GS 
Sbjct: 1029 GPELSAQPTPGPVPQVLPASLMVSASPAGPPLIPASRPPGPVLL------PPLQPNSGSL 1082

Query: 1432 TEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTF 1491
             + LP     L+   R     P      +   P P R      S +PP   SS  +  T 
Sbjct: 1083 PQVLPSPLGVLSGTSR----PPTPTLSLKPTPPAPVR-----LSPAPPPGSSSLLKPLTV 1133

Query: 1492 SPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESS 1551
             PG   P A A  ++ T + A  + +P    APTP+P               RL+     
Sbjct: 1134 PPGYTFPPAAATTTSTTTATATTTAVP----APTPAPQ--------------RLILSPDM 1175

Query: 1552 QE--APFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEP 1609
            Q       V+++   AS   R V  +  + PL    +    T      T   V QL    
Sbjct: 1176 QARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLT-----LTGAQVRQLAVGQ 1230

Query: 1610 PGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP-----RTPGTA 1664
            P P     V    A G   L    + PA    +  ++  PG + V   P      TP   
Sbjct: 1231 PRPLQRNVVHLVSAGGQHHLI---SQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPT 1287

Query: 1665 VVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLA----LDPIPGRQSTAVQPLVIN 1717
             + L  A    P  + +    +  +  +A + GL     L P P   S+ + P V+N
Sbjct: 1288 GLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGL-PAVLN 1343



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 79/341 (23%), Positives = 125/341 (36%), Gaps = 78/341 (22%)

Query: 540  PVGAPHRASGT------SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPL 593
            PV + H+   T      SP +++ P+   +P  P PA A        P+P  A     P+
Sbjct: 2413 PVISAHQTRSTTTPPRCSPARERVPRPAPRPR-PTPASAPAAIPALVPVPVSAPV---PI 2468

Query: 594  RASEP-SKTPSSVQEKK---TRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVV 649
             A  P +  P  +       +++P  + P   PPP  TP PA     +      P++P++
Sbjct: 2469 SAPNPITILPVHILPSPPPPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLL 2528

Query: 650  KAVPEAPKGGEAEDL-VG-KPYSQ---DASRSPQSLSDTGYSSDGISSSQSEITGVVQQE 704
               P  P      +L +G +P ++    A  SP+SL               E+  V   E
Sbjct: 2529 LGPPSVPISASVTNLPLGLRPEAELCAQALASPESL---------------ELASVASSE 2573

Query: 705  VEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQ-GLAPSERSKPLSSGT---GEEQKQR 760
               L            P ++  V   + P+ +    L PS  S  L +G+   G+EQ + 
Sbjct: 2574 TSSLSLV--------PPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQ-EA 2624

Query: 761  PHS-----LSITPEAFD------------------SDEELEDILEEDEDSAEWRRRREQQ 797
            P S     L++ PE  +                  SDE L++ LE D  S E    +   
Sbjct: 2625 PDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPT 2684

Query: 798  DTAESSDDF-----GSQLRHDYVEDSSEGGLSPLPPQPPAR 833
             + E   +       +         S EG   P P +PP R
Sbjct: 2685 SSPEKPQELVTAEVAAPSTSSSATSSPEG---PSPARPPRR 2722



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 46/166 (27%), Positives = 63/166 (37%), Gaps = 43/166 (25%)

Query: 3059 PAPQYSAGSGG--PTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTG 3116
            P+P+ SA + G  P     P H   + PGP++ P P             +PN        
Sbjct: 1381 PSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMP-------------IPNS------- 1420

Query: 3117 HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIAS-PVVPMSSAP 3175
                 +P+ +  S+   VP  S  P+              VPT     AS P+    SAP
Sbjct: 1421 -----SPLASPVSSTVSVPLSSSLPIS-------------VPTTLPAPASAPLTIPISAP 1462

Query: 3176 SETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYT 3221
               S SGPA+ +       P VP A   G  S +P+   PS S  T
Sbjct: 1463 LTVSASGPALLTSVTPPLAPVVPAA--PGPPSLAPSGASPSASALT 1506



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 55/230 (23%), Positives = 81/230 (35%), Gaps = 32/230 (13%)

Query: 2117 SGGGGPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLA------QYGPA 2170
            S GG   L+  QP H   + A        P  +   + P   P+P  L+      Q  P 
Sbjct: 1243 SAGGQHHLIS-QPAHVALIQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPT 1301

Query: 2171 AGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYAS 2230
                T V +++   A     DG+      TP+    P    P+S L  ++     RP  +
Sbjct: 1302 MVNNTGVVKIVVRQAP---RDGL------TPVPPLAPAPRPPSSGLPAVLNP---RPTLT 1349

Query: 2231 GGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKA 2290
             G    P     R PM  P +      L   P+P      S+  P   P+ +  P    +
Sbjct: 1350 PGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPE----VSASAPGAAPLTISSPLHVPS 1405

Query: 2291 PGAGGPSRP---------EMPVGAAREEPLPTTTPAAIKEAAGAPAPAPL 2331
               G  S P           PV +    PL ++ P ++     APA APL
Sbjct: 1406 SLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPL 1455



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 121/550 (22%), Positives = 191/550 (34%), Gaps = 81/550 (14%)

Query: 2736 GPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAH-LPPESLS-----QLVSRQPPK 2789
            GPT +S         TP P G         L +   A+ +PP  ++     ++V RQ P+
Sbjct: 1268 GPTPVSVLPSSTPSTTPAPTG---------LSLPLAANQVPPTMVNNTGVVKIVVRQAPR 1318

Query: 2790 SPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRP--MKTLQ 2847
                  +PV PL+P     +S   +    +  ++P +  T      +  +P P  ++ L 
Sbjct: 1319 DG---LTPVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLL 1375

Query: 2848 RSLSDPKP-LSPTAEESAKERFSLYQHQGGL--GSQVSALP-PNS--LVRKVKRTLPSPP 2901
            + +  P P +S +A  +A    S   H      G   S +P PNS  L   V  T+  P 
Sbjct: 1376 KLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPL 1435

Query: 2902 PEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLLRELDRDLRLVEHESTKLRKK 2961
               + LP++   +    A++ L   ++ P TV A+  +LL  +   L  V      +   
Sbjct: 1436 --SSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPV------VPAA 1487

Query: 2962 QAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPPLRGLGEHRDYLSDSELNQLR 3021
                             L LG+       +    G           H   L+ +  +   
Sbjct: 1488 PGPPSLAPSGASPSASALTLGLATAPSLSSSQTPG-----------HPLLLAPTSSHVPG 1536

Query: 3022 LQGCTTPAGQFVDFPATAAAPATPSGPT-AFQQPRFQPPAPQYSAGSGGP--------TQ 3072
            L     PA   V  PA+A A   PS P  A  Q     PA   S     P        T 
Sbjct: 1537 LNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTA 1596

Query: 3073 NGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLF 3132
               P+   P  P P   P+P   P  +    P      +  P    A  +P+P     L 
Sbjct: 1597 ILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLA 1656

Query: 3133 PVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPM--SSAPSETSYSGPAVSSGYE 3190
            P    +  P   P     + L     T    +A  + P    S+PS+T     ++ +G  
Sbjct: 1657 PSSTQTMLPAPVP-----SPLPSPASTQTLALAPALAPTLGGSSPSQTL----SLGTGNP 1707

Query: 3191 QGKVPEVPRAGDRGSVSQSPAPT-YPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAP 3249
            QG  P         ++S +PA +  P+ +   SL    P        +      S + AP
Sbjct: 1708 QGPFP-------TQTLSLTPASSLVPTPAQTLSLAPGPP--------LGPTQTLSLAPAP 1752

Query: 3250 DSQRLEPLGP 3259
                  P+GP
Sbjct: 1753 PLAPASPVGP 1762



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 41/167 (24%), Positives = 65/167 (38%), Gaps = 27/167 (16%)

Query: 3728 AHSGPAALQSKAEPQAQPQLQGR-QAAPG-----PQQSQSPSSRQIPSGAASRQPQTQQQ 3781
            A  G  +++S + P++ P + G  +AAP      P Q    + R I  G           
Sbjct: 2786 ASPGSPSVRSMSGPESSPPIGGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGD 2845

Query: 3782 QQGLGLQPPQQALTQARLQQQSQ-PTTRG----SAPAASQPA----GKPQPGPSTAT--- 3829
               L + PP     + R  ++++ P   G     AP+++         P PGP T     
Sbjct: 2846 GALLAITPPAVKRRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPGPETLIVAD 2905

Query: 3830 ---------GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPG 3867
                     GPQP GP    + N      +  ++GR P+A+  P PG
Sbjct: 2906 PVLEPQLIPGPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPG 2952



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 78/368 (21%), Positives = 126/368 (34%), Gaps = 55/368 (14%)

Query: 783  EDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPA---RAAELTD 839
            +DED     +  E++D  E+ +          VE+  EG  +    +      R  EL  
Sbjct: 283  DDEDGDFQPQEDEEEDDEETIE----------VEEQQEGNDAEAQRREIELLRREGELPL 332

Query: 840  EDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRP---EPSQEPAALPKR- 895
            E+ +R   L     E       T +S     + G ++G     P   E    P+A+ +R 
Sbjct: 333  EELLRS--LPPQLLEGPSSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQRN 390

Query: 896  RLPHNATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPS 955
            + P +     EE        EA D   T+          E    G   H ++L +     
Sbjct: 391  KQPWHPDEDDEEFT--ANEEEAEDEEDTIAA--------EEQLEGEVDHAMELSE----- 435

Query: 956  LDREPELEMESL-----------TGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEE 1004
            L RE EL ME L           +GS ED    E  +      P    G         E+
Sbjct: 436  LAREGELSMEELLQQYAGAYAPGSGSSEDEDEDEVDANSSDCEPE---GPVEAEEPPQED 492

Query: 1005 DSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQ 1064
             S  S S   R E+ + +      + G        S+ EE   EE E  + Q +  E E+
Sbjct: 493  SSSQSDSVEDRSEDEEDEHSEEEETSG-------SSASEESESEESEDAQSQSQADEEEE 545

Query: 1065 QRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCS 1124
                       RD+E+  A          P+ L P ++ +      ++ + +    ++  
Sbjct: 546  DDDFGVEYLLARDEEQSEADAGSGPPTPGPTTLGPKKEITDIAAAAESLQPKGYTLATTQ 605

Query: 1125 EYSPSPSL 1132
              +P P L
Sbjct: 606  VKTPIPLL 613



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 59/234 (25%), Positives = 73/234 (31%), Gaps = 27/234 (11%)

Query: 3679 ARPHSQPSSAPAMPKKGQPGYPSSAEYSQ----PSRASSAYHHASDSKKGSRQAHSGPAA 3734
            A P   P+S P  P    P  P+S    Q    P    S            +     P  
Sbjct: 1056 AGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVR 1115

Query: 3735 LQSKAEPQAQPQLQGRQAAPG---PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQ 3791
            L     P +   L+     PG   P  + + +S    +   +  P      Q L L P  
Sbjct: 1116 LSPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVPAPTPAPQRLILSPDM 1175

Query: 3792 QA-LTQARLQQQSQPTTRGSAPAASQPAGKP-----QPGPSTATGPQ----PAGPPRAEQ 3841
            QA L    +    Q  +    P A+    KP     Q    T TG Q      G PR  Q
Sbjct: 1176 QARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPRPLQ 1235

Query: 3842 TN--------GSKGTAKAPQQGRAPQA-QPAPGPGPAGVKAGARPGGTPGAPAG 3886
             N        G       P      QA  P PGP P  V   + P  TP AP G
Sbjct: 1236 RNVVHLVSAGGQHHLISQPAHVALIQAVAPTPGPTPVSVLPSSTPSTTP-APTG 1288



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 61/231 (26%), Positives = 84/231 (36%), Gaps = 31/231 (13%)

Query: 3681 PHSQPSSAPAMPKKGQP---GYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQS 3737
            P+S P ++P       P     P S   + P+ AS+       +      + SGPA L S
Sbjct: 1418 PNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPL--TVSASGPALLTS 1475

Query: 3738 KAEPQAQPQLQGRQAAPGPQQ----SQSPSSRQIPSGAASRQPQTQQQQQG--LGLQPPQ 3791
               P A        AAPGP        SPS+  +  G A+    +  Q  G  L L P  
Sbjct: 1476 VTPPLAPVV----PAAPGPPSLAPSGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTS 1531

Query: 3792 QALT--QARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG-----------PPR 3838
              +    + +     P    ++  AS     P P P+ A+   PA            P  
Sbjct: 1532 SHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMA 1591

Query: 3839 AEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPG 3889
            A QT      A +P    AP    AP PG A V A ++      AP+  PG
Sbjct: 1592 APQT---AILAPSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG 1639



 Score = 38.9 bits (89), Expect = 0.10
 Identities = 61/232 (26%), Positives = 84/232 (36%), Gaps = 52/232 (22%)

Query: 2120 GGPDLVQYQPQHGPGLS---APQSLVPLRPGLLGNPTFPEG-HPSPGNLAQYGPAAGQGT 2175
            G P L+     H PGL+   AP     L P       FP   +P+P   +   PA+    
Sbjct: 1522 GHPLLLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQ 1581

Query: 2176 AVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITA 2235
            A+   L   A  + A   I +    P  A LP       VL P           S G   
Sbjct: 1582 ALATPLAPMAAPQTA---ILAPSPAPPLAPLP-------VLAP-----------SPGAAP 1620

Query: 2236 VPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGG 2295
            V  +S T VP++AP    G +     P P+  P+ +                        
Sbjct: 1621 VLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLA------------------------ 1656

Query: 2296 PSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAP-LAGQKPPADAAPGGGS 2346
            PS  +  + A    PLP+  PA+ +  A APA AP L G  P    + G G+
Sbjct: 1657 PSSTQTMLPAPVPSPLPS--PASTQTLALAPALAPTLGGSSPSQTLSLGTGN 1706



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 48/180 (26%), Positives = 58/180 (32%), Gaps = 51/180 (28%)

Query: 3027 TPAGQFVDFPAT--AAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYP 3084
            TPA   V  PA   + AP  P GPT  Q     P  P   A   GP     PAH     P
Sbjct: 1719 TPASSLVPTPAQTLSLAPGPPLGPT--QTLSLAPAPPLAPASPVGPA----PAHTLTLAP 1772

Query: 3085 GPSTY----------------PAPAFPPGASY-----PAEPGLPNQQAFRPTGHYAGQTP 3123
              S+                 P P   P A+      PA    P  QA       +G  P
Sbjct: 1773 ASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTLALAPASTQSPASQASSLVVSASGAAP 1832

Query: 3124 MPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGP 3183
            +P T  +  PV  D                    P    + + P  P S+A   TS+ GP
Sbjct: 1833 LPVTMVSRLPVSKDE-------------------PDTLTLRSGPPSPPSTA---TSFGGP 1870



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 86/427 (20%), Positives = 144/427 (33%), Gaps = 76/427 (17%)

Query: 1239 QAAQPAAEGTPASLG----AAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNA- 1293
            +A +P AE    S      AA+ E++    +  ++  +AS  +++  E K+ E+Q   A 
Sbjct: 2284 EAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQAEEQVEAAR 2343

Query: 1294 -------ESAYMDPMKQNGGPLTPGTSPT-----------QLAAPVSFSTPTSSDSSGGR 1335
                   E  +  P ++  GP     S             +  AP    T  S    G R
Sbjct: 2344 KDLDQAKEEVFRLPQEEEEGPGAGDESSCGTGGGTHRRSKKAKAPERPGTRVSERLRGAR 2403

Query: 1336 VIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPR 1395
               + +   H    +    +  ++P   S A + +  P  +   TPA+      PA +P 
Sbjct: 2404 A--ETQGANHTPVISAHQTRSTTTPPRCSPARERVPRPAPRPRPTPASA-----PAAIPA 2456

Query: 1396 GYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLS 1455
                P S      +P P S  +     P            P  PS +      A   P +
Sbjct: 2457 LVPVPVS------APVPISAPNPITILPV------HILPSPPPPSQIPPCSSPACTPPPA 2504

Query: 1456 ASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPAS 1515
             +     TP P++      SS   L P S   S + +   +G R  AE   Q  +   + 
Sbjct: 2505 CTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLGLRPEAELCAQALASPESL 2564

Query: 1516 DMPRSPGAPTPS----------PMVAQGTQTPHR-----PSTPRLVWQESS------QEA 1554
            ++     + T S          P+  +      +     PS P L  +  S      QEA
Sbjct: 2565 ELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNGQEQEA 2624

Query: 1555 PFMV-------------ITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPS 1601
            P                + L    S+   +  ++AS  PL  P E   T+   ++   P+
Sbjct: 2625 PDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSEELTEAKTPT 2684

Query: 1602 VSQLPPE 1608
             S   P+
Sbjct: 2685 SSPEKPQ 2691



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 63/257 (24%), Positives = 88/257 (34%), Gaps = 31/257 (12%)

Query: 596 SEPSKTPSSVQEKKTRVPTK-AEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654
           S PS+TPSS        P + AE  P    E  P P+        R  +P  P       
Sbjct: 348 SSPSQTPSSHDSDTRDGPEEGAEEEPPQVLEIKPPPSAVTQ----RNKQPWHPDEDDEEF 403

Query: 655 APKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVT 714
                EAED       +D   + + L   G     +  S+    G +  E      AG  
Sbjct: 404 TANEEEAED------EEDTIAAEEQLE--GEVDHAMELSELAREGELSMEELLQQYAGAY 455

Query: 715 GPHPPSPS-----EIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGE---EQKQRPHSLSI 766
            P   S       E+    S   P    +   P +      S + E   E ++  HS   
Sbjct: 456 APGSGSSEDEDEDEVDANSSDCEPEGPVEAEEPPQEDSSSQSDSVEDRSEDEEDEHSEEE 515

Query: 767 TPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQ--LRHDYVEDSSEGGLS 824
                 + EE E   EE ED+    + + Q D  E  DDFG +  L  D  +  ++ G  
Sbjct: 516 ETSGSSASEESES--EESEDA----QSQSQADEEEEDDDFGVEYLLARDEEQSEADAGSG 569

Query: 825 PLPPQPPARA--AELTD 839
           P  P P       E+TD
Sbjct: 570 PPTPGPTTLGPKKEITD 586



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 30/88 (34%), Positives = 42/88 (47%), Gaps = 13/88 (14%)

Query: 2339 DAAPGGGSGALSRPGFEKEEASQEERQ-RKQQEQLLQLER----------ERVELEKLRQ 2387
            D  P G      RPG E EE S+ E++     EQL  +ER          E V  E+L+Q
Sbjct: 2275 DGFPAGEGEEAGRPGAEDEEMSRAEQEIAALVEQLTPIERYAMKFLEASLEEVSREELKQ 2334

Query: 2388 LRLQEELERERVELQRHREEEQLLVQRE 2415
               +E++E  R +L + +EE   L Q E
Sbjct: 2335 --AEEQVEAARKDLDQAKEEVFRLPQEE 2360



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 82/336 (24%), Positives = 116/336 (34%), Gaps = 64/336 (19%)

Query: 1309 TPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSP-------A 1361
            TP  + T   A     TP+S    G    P V ++   A  T  PL L           A
Sbjct: 2506 TPPPAHTPPPAQTCLVTPSSPLLLGP---PSVPIS---ASVTNLPLGLRPEAELCAQALA 2559

Query: 1362 SPSS------ASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGS-ERSPSPSS 1414
            SP S      AS E        P      AV   P       +TP++P+ + E    P+ 
Sbjct: 2560 SPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSAPSLTLEAGSIPNG 2619

Query: 1415 TAHSYGHSP--TTANYGSQTEDLPQAPS---GLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
                   S   TT     + E+LP   S   GL     AA ++PL        T +    
Sbjct: 2620 QEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQEPLEADRTSE---- 2675

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                 + +P  SP  P E  T         ++A  S + PSPA      R P   T + +
Sbjct: 2676 -ELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPA------RPPRRRTSADV 2728

Query: 1530 V--AQGTQTPHRPSTPRLVWQ-----------------------ESSQEAPFMVITLASD 1564
                QGT  P +P  P+++ +                        +S   P +  T AS 
Sbjct: 2729 EIRGQGTGRPGQPPGPKVLRKLPGRLVTVVEEKELVRRRRQQRGAASTLVPGVSETSASP 2788

Query: 1565 ASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPP 1600
             S   R +    S+ P+  P E  P++   S  TPP
Sbjct: 2789 GSPSVRSMSGPESSPPIGGPCEAAPSS---SLPTPP 2821



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 50/199 (25%), Positives = 70/199 (35%), Gaps = 30/199 (15%)

Query: 1305 GGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPS 1364
            G P  P  + T    P S   PT + +      P +  TQ  +     PL    +PASP 
Sbjct: 1705 GNPQGPFPTQTLSLTPASSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPL----APASPV 1760

Query: 1365 SASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSST-----AHSY 1419
                        GP    T  +AP  A      + PAS      SP+P  T     A + 
Sbjct: 1761 ------------GPAPAHTLTLAP--ASSSASLLAPASVQTLTLSPAPVPTLGPAAAQTL 1806

Query: 1420 GHSP-TTANYGSQTEDLPQAPSGLAAAGRAAREK-PLSASDGE-----GGTPQPSRAYSY 1472
              +P +T +  SQ   L  + SG A        + P+S  + +      G P P    + 
Sbjct: 1807 ALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATS 1866

Query: 1473 FASSSPPLSPSSPSESPTF 1491
            F    P   P  P  SP +
Sbjct: 1867 FGGPRPRRQPPPPPRSPFY 1885



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 58/231 (25%), Positives = 91/231 (39%), Gaps = 60/231 (25%)

Query: 2296 PSRPEMPV--------GAAREEPL-PTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGS 2346
            P+ P++PV        G     P+ P ++ +     AG  +P  +A Q    D  PG   
Sbjct: 7    PAHPQLPVLQTQMVSDGMTGSNPVSPASSSSPASSGAGGISPQHIA-QDSSLDGPPGPPD 65

Query: 2347 GA--------LSR--------PGFEKEEASQEERQRKQQEQLLQLERERVELEK-----L 2385
            GA        LS+        P +EK  A   E+ + + E    +E    EL K     L
Sbjct: 66   GATVPLEGFSLSQAADLANKGPKWEKSHAEIAEQAKHEAE----IETRIAELRKEGFWSL 121

Query: 2386 RQLRLQEELERERVELQRHREEEQLLVQRELQELQ------------TIKHHVLQQQQEE 2433
            ++L    E  R +       EE Q L     QE +             I+HH  Q+Q+EE
Sbjct: 122  KRLPKVPEPPRPKGHWDYLCEEMQWLSADFAQERRWKRGVARKVVRMVIRHHEEQRQKEE 181

Query: 2434 RQAQFALQREQLAQQRLQLEQIQQLQQ---------QLQQQLEEQKQRQKA 2475
            R    A + EQ   +R+     + ++Q         Q +QQ   +++R+KA
Sbjct: 182  R----ARREEQAKLRRIASTMAKDVRQFWSNVEKVVQFKQQSRLEEKRKKA 228



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 46/201 (22%), Positives = 69/201 (34%), Gaps = 22/201 (10%)

Query: 3675 GRHEARPHSQPSSAPAMPKKGQP--GYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGP 3732
            G    R  S P S+P +   G P    PSS+  + P +   A  H      G     +G 
Sbjct: 2789 GSPSVRSMSGPESSPPI---GGPCEAAPSSSLPTPPQQPFIARRHIELGVTGGGSPENGD 2845

Query: 3733 AALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSR-----QIPSGAASRQPQTQQQQQGLGL 3787
             AL +   P  +     R+    P++++SP+       + PS     +        G   
Sbjct: 2846 GALLAITPPAVK-----RRRGRPPKKNRSPADAGRGVDEAPSSTLKGKTNGADPVPG--- 2897

Query: 3788 QPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKG 3847
             P    +    L+ Q  P   G  P   QP  +P P  S     +   PP+A        
Sbjct: 2898 -PETLIVADPVLEPQLIP---GPQPLGPQPVHRPNPLLSPVEKRRRGRPPKARDLPIPGT 2953

Query: 3848 TAKAPQQGRAPQAQPAPGPGP 3868
             + A       + QP P P P
Sbjct: 2954 ISSAGDGNSESRTQPPPHPSP 2974



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 41/161 (25%), Positives = 65/161 (40%), Gaps = 30/161 (18%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQPPAP------QYSAGS------------GGPTQNGFPA 3077
            PA+    A+P+GP     P  +PP P      Q ++GS             G ++   P 
Sbjct: 1046 PASLMVSASPAGPPLI--PASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPT 1103

Query: 3078 HQA-PTYPGPSTYPAPAFPPGASYPAEP-GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVP 3135
                PT P P    +PA PPG+S   +P  +P    F P       T   T  +T  P  
Sbjct: 1104 LSLKPTPPAPVRL-SPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTATATTTAVP-- 1160

Query: 3136 ADSRAPLQKPRQTSLA-DLEQKVPTNYEVIASPVVPMSSAP 3175
                AP   P++  L+ D++ ++P+   V    +  ++  P
Sbjct: 1161 ----APTPAPQRLILSPDMQARLPSGEVVSIGQLASLAQRP 1197



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 72/290 (24%), Positives = 103/290 (35%), Gaps = 37/290 (12%)

Query: 2117 SGGGGPDLVQYQ-------PQHGPGLS-APQSLVPLRPGLLGNPTFPEGHPSPGNLAQYG 2168
            S G  P L   Q       P   PG S A  S VP    +L   +     P+P       
Sbjct: 1615 SPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLPAPVPSPLPS 1674

Query: 2169 PAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAA--TLPITTQPASVLRPMVRGGM-Y 2225
            PA+ Q  A+   L  T    +    +      P     T  ++  PAS L P     +  
Sbjct: 1675 PASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLVPTPAQTLSL 1734

Query: 2226 RPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAE-------- 2277
             P    G T     SL   P +AP  P+GP   +          AS + PA         
Sbjct: 1735 APGPPLGPTQT--LSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTLSP 1792

Query: 2278 GPVYLGKPAAAKAPGAGGPSRPEMP--------VGAAREEPLPTTTPAAIKEAAGAPAPA 2329
             PV    PAAA+   A  P+  + P        V A+   PLP T  + +  +   P   
Sbjct: 1793 APVPTLGPAAAQTL-ALAPASTQSPASQASSLVVSASGAAPLPVTMVSRLPVSKDEPDTL 1851

Query: 2330 PLAG--QKPPADAAPGGGSGALSRPGFEKE-----EASQEERQRKQQEQL 2372
             L      PP+ A   GG     +P          ++ +E+R+R++ E+L
Sbjct: 1852 TLRSGPPSPPSTATSFGGPRPRRQPPPPPRSPFYLDSLEEKRKRQRSERL 1901



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 53/219 (24%), Positives = 79/219 (36%), Gaps = 35/219 (15%)

Query: 1837 PGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEE---PAGALDLTGMR 1893
            P +E + +      S  L     P+    +  +   GT  T+LPE    P    +  G+ 
Sbjct: 2594 PVSEKNLSLTPSAPSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLE 2653

Query: 1894 -PESQLACCDMVYKLPFGSSCTG-------TFHPAPSVPEKSM-ADAAPPGQSSSPFYGP 1944
             P S  A  D   + P  +  T        T   +P  P++ + A+ A P  SSS    P
Sbjct: 2654 LPPS--AASDEPLQEPLEADRTSEELTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSP 2711

Query: 1945 RDPEPPEPP--------TYRAQGVVGPGPHEEQRPYP---QGLPGRLYSSMSDTNLA--- 1990
              P P  PP          R QG   PG    Q P P   + LPGRL + + +  L    
Sbjct: 2712 EGPSPARPPRRRTSADVEIRGQGTGRPG----QPPGPKVLRKLPGRLVTVVEEKELVRRR 2767

Query: 1991 ---EAGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSLG 2026
                   +     + +    PG  S   +S  + S  +G
Sbjct: 2768 RQQRGAASTLVPGVSETSASPGSPSVRSMSGPESSPPIG 2806



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 55/193 (28%), Positives = 73/193 (37%), Gaps = 47/193 (24%)

Query: 2148 LLGNPTFPEG----HPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIA 2203
            ++ NP  P G     P PG      P  G    V Q+LP++  V A      S    P+ 
Sbjct: 1011 VVNNPRAPLGPVPVRPPPGPELSAQPTPGP---VPQVLPASLMVSA------SPAGPPL- 1060

Query: 2204 ATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGP-TGLYRYP 2262
              +P +  P  VL P ++        SG +           P + P  PLG  +G  R P
Sbjct: 1061 --IPASRPPGPVLLPPLQPN------SGSL-----------PQVLPS-PLGVLSGTSRPP 1100

Query: 2263 APSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRP-EMPVG----AAREEPLPTTTPA 2317
             P+     S  P    PV L   + A  PG+    +P  +P G     A      TTT  
Sbjct: 1101 TPT----LSLKPTPPAPVRL---SPAPPPGSSSLLKPLTVPPGYTFPPAAATTTSTTTAT 1153

Query: 2318 AIKEAAGAPAPAP 2330
            A   A  AP PAP
Sbjct: 1154 ATTTAVPAPTPAP 1166



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 32/133 (24%), Positives = 48/133 (36%), Gaps = 15/133 (11%)

Query: 3740 EPQAQPQLQGRQAAPGPQQSQSP------SSRQIPSGAASRQPQTQQQQQGLGLQPPQQA 3793
            E +A    +G      P+  + P      +  ++P  AAS +P     Q+ L      + 
Sbjct: 2621 EQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPL----QEPLEADRTSEE 2676

Query: 3794 LTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQ 3853
            LT+A+    S    +    A            S+  GP PA PPR      +    +   
Sbjct: 2677 LTEAKTPTSSPEKPQELVTAEVAAPSTSSSATSSPEGPSPARPPRRR----TSADVEIRG 2732

Query: 3854 QGRAPQAQPAPGP 3866
            QG     QP PGP
Sbjct: 2733 QGTGRPGQP-PGP 2744



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%)

Query: 2291 PGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAP--APAPLAGQKP 2336
            P    P+R  +P  A R  P P + PAAI      P  AP P++   P
Sbjct: 2426 PPRCSPARERVPRPAPRPRPTPASAPAAIPALVPVPVSAPVPISAPNP 2473


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 87.0 bits (214), Expect = 3e-16
 Identities = 331/1593 (20%), Positives = 541/1593 (33%), Gaps = 230/1593 (14%)

Query: 23   PGPGP-----GPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG---------PGPG 68
            P P P     GP P A  P  A   GG  P   A    +  PV  P          P   
Sbjct: 350  PSPSPERSSTGPEPPAPTPLLAERHGGS-PQPLATTPLSQEPVNPPSEASPTRDRSPPKS 408

Query: 69   PGPGPGSTSRRLDPKEP----LGNQRAASP-TPKQASATTPGHESPRETRAQGPAGQEAD 123
            P   P S+S    P  P    +    ++SP +PK A A     E      ++  +   A 
Sbjct: 409  PEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAK 468

Query: 124  GPRRTLQVDSRTQRSGRSPSVSP---DRGSTPT----SPYSVPQIAPLPSSTLCPICKTS 176
              +      SR     RSP+ +     R  TPT    S    PQ     S+      ++ 
Sbjct: 469  RDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSP 528

Query: 177  DL---TSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA 233
                 + +P +P ++       +  ++       H            +     G   +  
Sbjct: 529  QRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRT 588

Query: 234  P-RSKSQQQLHSPALSPAHSPAKQPLGK---PDQERSRGPGGPQPGSRQAETARATSVPG 289
            P R +S+ +  +   S + +PA++   +   P + RSR     +  SR    AR +   G
Sbjct: 589  PARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRS---G 645

Query: 290  PAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGK 349
             +++  P   GR   + P   +   +  R PA  +  +S +  PA  G + +++    G+
Sbjct: 646  RSRSRTPARRGRSRSRTP--ARRGRSRSRTPARRS-GRSRSRTPARRGRS-RSRTPRRGR 701

Query: 350  LFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGP--- 406
                  SL+ +  +           G  +  K   +     +   + P+   S       
Sbjct: 702  --SRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRS 759

Query: 407  ----GPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKER 462
                 P   AK+    R    SG    PK    T P+  R+    +S+  AK +T P+  
Sbjct: 760  RSLSSPRSKAKSRLSLRRSL-SGSSPCPKQKSQTPPRRSRS---GSSQPKAKSRTPPRRS 815

Query: 463  AICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP-----TPHLVEKTEWLCLNCQT 517
                         S SP       T   Q  +    +P     TP           N Q+
Sbjct: 816  R-----------SSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQS 864

Query: 518  KRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGP----QGLGQPSGPLPAKAS 573
                  S  E +P P   S+ P   + H  SG+SP + K      Q   + S P P   +
Sbjct: 865  VTPQRRSCFESSPDPELKSRTP---SRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921

Query: 574  PLSTK-------ASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPET 626
             +S +       +SP PS+ + +  P R    S++ S     ++R+  +        P+T
Sbjct: 922  IISPRQRSHSGSSSPSPSRVTSRTTPRR----SRSVSPCSNVESRLLPRYSHSGSSSPDT 977

Query: 627  TPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDA--SRSPQSLSDTG 684
               P TP  +S      P   V    P  P    ++    +  S+D+     P SLS   
Sbjct: 978  KVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLS--- 1034

Query: 685  YSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSE 744
                G+ SS             QL     T P        H+  +S   + Q+   +PS 
Sbjct: 1035 -LCAGVKSSTPPGESYFGVSSLQLKGQSQTSPD-------HRSDTSSPEVRQSHSESPSL 1086

Query: 745  RSKPLSSGTGEEQKQR---PHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAE 801
            +SK  +S  G   +         S +P   D  E     + +   S E + R +   ++ 
Sbjct: 1087 QSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPE-QSRFQSDSSSY 1145

Query: 802  SSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDD 861
             + D  S L    +E +       LPPQ  A A+    +D      ++   E   + +D 
Sbjct: 1146 PTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDT 1205

Query: 862  TATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGS 921
              T  R       ++ G    PE  ++ +ALP        ++  EEL+      E  + S
Sbjct: 1206 LRTPPR-------ERSGAGSSPETKEQNSALP-------TSSQDEELM------EVVEKS 1245

Query: 922  GTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSS 981
                G +    + EL    +             + +  PE+E         D+S+ + +S
Sbjct: 1246 EEPAGQILSHLSSELKEMST------------SNFESSPEVEERPAVSLTLDQSQSQ-AS 1292

Query: 982  TLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPL---LPTIE 1038
                  PS  S       S   ++  +SP     L E         R+ GPL   + T  
Sbjct: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSP-----LRENSFGSPLEFRNSGPLGTEMNTGF 1347

Query: 1039 DSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNL- 1097
             S  +E+L        E +   ++++Q  RS+   +     EL      +   +   ++ 
Sbjct: 1348 SSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSS----SELSPDAVEKAGMSSNQSIS 1403

Query: 1098 SPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPT 1157
            SP+ DA P              R+   E S S S     + L   PSR  +SGS   L  
Sbjct: 1404 SPVLDAVP--------------RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL-- 1447

Query: 1158 FMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQ 1217
                          S TPS    L  +    +++ R      R + +   +  P   P  
Sbjct: 1448 -----------RDGSGTPSR-HSLSGSSPGMKDIPRTP---SRGRSECDSSPEPKALPQT 1492

Query: 1218 PTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRD 1277
            P  PR         ++     +   P  E + +   ++V ++ +  +    R R  SS++
Sbjct: 1493 PR-PR-----SRSPSSPELNNKCLTPQRERSGSE--SSVDQKTVARTPLGQRSRSGSSQE 1544

Query: 1278 LAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVI 1337
            L                      +K +  P     S +   +     TP    S  G   
Sbjct: 1545 L---------------------DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGS-S 1582

Query: 1338 PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGY 1397
            P+V      +K    P +  S  +SP    K    P +Q     +    AP P  LPR  
Sbjct: 1583 PEVD-----SKSRLSPRRSRSG-SSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636

Query: 1398 MTPASPAGSERSPSP---SSTAHSYGHSP--TTANYGSQTEDLPQAPSGLAAAGRAAREK 1452
             + +S  G  R PSP   SST  S  H P   TA  GS++   P+  S      R++R  
Sbjct: 1637 RSGSSSKG--RGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694

Query: 1453 P-LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSP 1511
            P L+         + + +     S +PP    SPS S    P +    +    S  +P  
Sbjct: 1695 PELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSP-EPAEKSRSSRRRRSASSPRT 1753

Query: 1512 APASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
               S   RS   P+P P   Q +++  R    R
Sbjct: 1754 KTTSRRGRS---PSPKPRGLQRSRSRSRREKTR 1783



 Score = 77.8 bits (190), Expect = 2e-13
 Identities = 332/1696 (19%), Positives = 546/1696 (32%), Gaps = 265/1696 (15%)

Query: 55   TAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRA 114
            ++ PP   P     P P        + P++   +  ++SP+P + ++ T    +PR +R+
Sbjct: 901  SSTPPRQSPSRSSSPQP---KVKAIISPRQR-SHSGSSSPSPSRVTSRT----TPRRSRS 952

Query: 115  QGP--------------AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQ 160
              P              +G  +   +   +   R   SG        +  TP  P     
Sbjct: 953  VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS 1012

Query: 161  IAPLPSSTL-------CP----ICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHL 209
             +P P           CP    +C     ++ P +  F   +    ++  Q   +P+   
Sbjct: 1013 KSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSL---QLKGQSQTSPDHRS 1069

Query: 210  TQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGK--------- 260
                  +  +     +L     T+P+    +         + SP +Q  G+         
Sbjct: 1070 DTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKS 1129

Query: 261  ---PDQERSRGPGGPQP--------GSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQP 309
               P+Q R +      P        G  + ETA +       + A PP+    +  P Q 
Sbjct: 1130 GMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKE-----KMALPPQEDATASPPRQK 1184

Query: 310  TK--PSTAEPRPPAGEAPAKSATAVP---AGLGATEQTQEGLTGKLFGLGASLLTQASTL 364
             K  P   + RP +      +    P   +G G++ +T+E  +           +Q   L
Sbjct: 1185 DKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSA------LPTSSQDEEL 1238

Query: 365  MSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGS 424
            M V  +++   +PA   G      +   KE       S P     P             S
Sbjct: 1239 MEVVEKSE---EPA---GQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQAS 1292

Query: 425  GPGA-LPKTGGTTSPKHGRAEHQAASKAAAKPKTM--PKERAICPLCQAELNVGSKSPAN 481
                 +P    +    H   EH+  S +  +  +   P E         E+N G  S   
Sbjct: 1293 LEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVK 1352

Query: 482  YNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPV 541
             +      L    L      P L  K +    +  +   L     E   +    S   PV
Sbjct: 1353 ED------LNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPV 1406

Query: 542  -----GAPHRASGTSPLKQKGPQGLGQ-PSGPLPAKASPLSTKASPLPSKASPQAKPLRA 595
                   P R   +S    +   GL + PS    + +SP     S  PS+ S        
Sbjct: 1407 LDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGM 1466

Query: 596  SEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGV------RRAEPATPVV 649
             +  +TPS  + +    P + + +P+ P   + +P++P++ +        R    ++   
Sbjct: 1467 KDIPRTPSRGRSECDSSP-EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQ 1525

Query: 650  KAVPEAPKG-----GEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQ- 703
            K V   P G     G +++L  KP     S SPQ  S++  S D  + +++ +    +  
Sbjct: 1526 KTVARTPLGQRSRSGSSQELDVKP-----SASPQERSESDSSPDSKAKTRTPLRQRSRSG 1580

Query: 704  EVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQG--------LAPSERSKPLSSGTGE 755
               ++DS     P         +V    R   +AQ          AP+ R+ P  S +G 
Sbjct: 1581 SSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGS 1640

Query: 756  EQKQR---PHSLSITPEAFDSDEELEDILEEDEDSAEWR-------RRREQQDTAESSDD 805
              K R   P   S T  + +   +          S E +       RRR  + + E +  
Sbjct: 1641 SSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRK 1700

Query: 806  FGSQLRHDYVEDSSEGGLSPLPPQ----PPARAAELTDEDFMRRQILEMSAEEDNLEEDD 861
                 R      S E   S  PP+    P   + E  ++    R+    S+         
Sbjct: 1701 ARLSRRSRSASSSPETR-SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTK----- 1754

Query: 862  TATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGS 921
              TS RG +     +G  R R    +E     +RR                GS+++T  S
Sbjct: 1755 -TTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRR-------------DRSGSSQST--S 1798

Query: 922  GTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSS 981
               Q    R +       GS  H             R P  +  S T S   R R   S 
Sbjct: 1799 RRRQRSRSRSRVTRRRRGGSGYHS------------RSPARQESSRTSSRRRRGR---SR 1843

Query: 982  TLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSS 1041
            T P S     S TSP         +  +  RR R   ++    +R RS     P     S
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSR---SRTPLISRRRSRSRTSPVSRRRS 1900

Query: 1042 EEEELREEEELLREQEKMREVEQQRIRSTARKT----RRDKEELRAQRRRERSKTPPSNL 1097
                 R    + R + + R     R RS +R      RR +      RRR RS+TPP   
Sbjct: 1901 -----RSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTR 1955

Query: 1098 SPIEDASPTEELRQAAEMEE--LHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNL 1155
                  +P    R++         R S S  SP     S +       S + +  S    
Sbjct: 1956 RRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRT-----SPVTRRRSRSRT 2010

Query: 1156 PTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGP 1215
                   S + TP        S  PL   + +      ++ L  R++ ++   R   G  
Sbjct: 2011 SPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRS----RSPLAIRRRSRSRTPRTARGKR 2066

Query: 1216 SQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG------TPASLGAAVYEEILQTSQSIVR 1269
            S    P  +       ++      A  PA          P +L ++      + S S   
Sbjct: 2067 SLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTP 2126

Query: 1270 MRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSS 1329
            + +  S  +          + L +    M  ++Q GG +  G  P               
Sbjct: 2127 LDRCRSPGML---------EPLGSSRTPMSVLQQAGGSMMDGPGPR-------------- 2163

Query: 1330 DSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPC 1389
                   IPD + T       Q  + L  +  S  +A      P     G  A  +  P 
Sbjct: 2164 -------IPDHQRTSVPENHAQSRIALALTAISLGTARPP---PSMSAAGLAARMSQVPA 2213

Query: 1390 PAGLPRGYMTPASPAGSERSPSPSSTAHSYGHS-----PTTANYGSQTEDLPQAPSGLAA 1444
            P  L      PA+   S R P+ S+ A +   +     PT  N          A   LA+
Sbjct: 2214 PVPLMSLRTAPAANLAS-RIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLAS 2272

Query: 1445 AGRAAREKPLSASDGE-----------GGTPQPSRAYSYFASSSPPLSPSSPSESPTFSP 1493
               A     ++ +D               TP    A S   S +PP + + PS S T   
Sbjct: 2273 PRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRT--- 2329

Query: 1494 GKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQE 1553
                P+A A  +   P  A A+      G+ T + + A  + T  R +        +S  
Sbjct: 2330 ----PQAPASANLVGPRSAHATAPVNIAGSRTAAAL-APASLTSARMAPALSGANLTSPR 2384

Query: 1554 APFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTT-----PPSVSQLPPE 1608
             P       S  +S   +  A + T P  +P++++ T+      +      PS S LPP 
Sbjct: 2385 VPLSAYERVSGRTSPPLLDRARSRTPP-SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPA 2443

Query: 1609 PPGPPGFPRVPSAGAD 1624
               P     VPSA +D
Sbjct: 2444 QDQPRS--PVPSAFSD 2457



 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 327/1667 (19%), Positives = 527/1667 (31%), Gaps = 224/1667 (13%)

Query: 62   GPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHES----PRETRAQGP 117
            G  P         S+   +D    LG  R  +   K+  A  P  ++    PR+     P
Sbjct: 1130 GMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSP 1189

Query: 118  AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSD 177
               + D P  +L      +   R      +R    +SP +  Q + LP+S+     +  +
Sbjct: 1190 FPVQ-DRPESSLVFKDTLRTPPR------ERSGAGSSPETKEQNSALPTSSQDE--ELME 1240

Query: 178  LTSTPSQPNFNTCTQCHN--KVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPR 235
            +     +P     +   +  K  +   F  +P + +         Q Q    ++    P 
Sbjct: 1241 VVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPS 1300

Query: 236  SKSQQQLHSPALSPAH-----SPAKQ-PLGKPDQERSRGPGGPQPGSR-QAETARATSVP 288
              S      P  SP H     SP ++   G P + R+ GP G +  +   +E     + P
Sbjct: 1301 MASSWG--GPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGP 1358

Query: 289  GPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTG 348
               Q    P +  +  Q  + +  S++E  P A E          AG+ + +        
Sbjct: 1359 FLNQLETDPSLD-MKEQSTRSSGHSSSELSPDAVEK---------AGMSSNQSI------ 1402

Query: 349  KLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGP 408
                        +S ++   P   ++ + + S  +P++   D       +   SG  PG 
Sbjct: 1403 ------------SSPVLDAVPRTPSR-ERSSSASSPEM--KDGLPRTPSRRSRSGSSPGL 1447

Query: 409  APGAKTEPGARMGPGSGPGA--LPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICP 466
              G+ T P      GS PG   +P+T     P  GR+E  ++ +  A P+T P+ R+  P
Sbjct: 1448 RDGSGT-PSRHSLSGSSPGMKDIPRT-----PSRGRSECDSSPEPKALPQT-PRPRSRSP 1500

Query: 467  LCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLG 526
                       SP   N C T + +            + +KT       Q  R       
Sbjct: 1501 ----------SSPELNNKCLTPQRERSG-----SESSVDQKTVARTPLGQRSRSGSSQEL 1545

Query: 527  EPTPLPPPTSQQPPVGAPH-RASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPS- 584
            +  P   P  +     +P  +A   +PL+Q+   G   P     ++ SP  +++   P  
Sbjct: 1546 DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSG-SSPEVDSKSRLSPRRSRSGSSPEV 1604

Query: 585  KASPQAKPLRASEPSKTPSSVQEKKTRVPTKAE---------PMPKPPPETTPTPATPKV 635
            K  P+A P   S    +P         +P ++          P P+    T  +P  P  
Sbjct: 1605 KDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPK 1664

Query: 636  KSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQS 695
                RR   ++P  K     P           P  + +  SP+       S    S+S S
Sbjct: 1665 SRTARRGSRSSPEPKTKSRTP-----------PRRRSSRSSPELTRKARLSRRSRSASSS 1713

Query: 696  EITGVVQQEVEQLDSAGVTGPHPPSPSEIHK----VGSSMRPLLQAQGLAPSERSKPLSS 751
              T   +       S  V+ P P   S   +      S        +G +PS + + L  
Sbjct: 1714 PETRS-RTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQR 1772

Query: 752  GTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQLR 811
                 ++++  +      +  S             S   RRRR       S     S  R
Sbjct: 1773 SRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRR-----GGSGYHSRSPAR 1827

Query: 812  HDYVEDSSEG--GLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGL 869
             +    SS    G S  PP    R+   T     +R     S          T    R  
Sbjct: 1828 QESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRR 1887

Query: 870  AKHGTQK-GGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGL 928
            ++  T      R R   S        R  P +         P       +    T +   
Sbjct: 1888 SRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR 1947

Query: 929  RRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTP 988
             R   +    + S    +   +    +    P     S + +     R   S T P +  
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRT---SPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004

Query: 989  SYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPL-LPTIEDSSEEEELR 1047
               S TSP +       +  +  RR R       RK R RS  PL +     S      R
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK-RSRSRSPLAIRRRSRSRTPRTAR 2063

Query: 1048 EEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLS--------- 1098
             +  L R    +R    +R  S +   R       A R    S+TPP  L+         
Sbjct: 2064 GKRSLTRSPPAIR----RRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSR 2119

Query: 1099 PIEDASPTEELRQAAEMEEL----------------------------HRSSCSEYSPSP 1130
            P    +P +  R    +E L                             R+S  E     
Sbjct: 2120 PSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQS 2179

Query: 1131 SLDSEAEALDGGPSRLYKSGSEYNLPTFMS-------LYSPTETPSGS--STTPSSGRPL 1181
             +     A+  G +R   S S   L   MS       L S    P+ +  S  P++    
Sbjct: 2180 RIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAA 2239

Query: 1182 KSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAA 1241
             +   A    +  A  L   +  AA A      P     P  +   + +  T      A 
Sbjct: 2240 MNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPT----APAV 2295

Query: 1242 QPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPM 1301
              A   TPA+L A      L  + S      A+    +           +   SA+    
Sbjct: 2296 NLAGARTPAALAA------LSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT-- 2347

Query: 1302 KQNGGPLTPGTSPTQLA-APVSFSTPTSSDSSGGRVIPDVRVT----QHFAKETQDPLKL 1356
                 P+    S T  A AP S ++   + +  G  +   RV     +  +  T  PL  
Sbjct: 2348 ----APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLD 2403

Query: 1357 HSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGS---------- 1406
             +   +P SA  +  M   + P   +    AP  + LP     P SP  S          
Sbjct: 2404 RARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI 2463

Query: 1407 -ERSPSPSSTAHSYGHSPTTANY-------------GSQTEDLPQAPSGLAAAGRAAREK 1452
             + +P   S + S G   TT +              G    D+ + P+   A   +A   
Sbjct: 2464 AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAA 2523

Query: 1453 PLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPA 1512
               A +    +   S + S  +SSS   S SS   S + S G   P        + PSP 
Sbjct: 2524 LQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPT 2583

Query: 1513 PASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMV 1572
            PA       G P P P  A+  +     S+       SS  +     + +S +SS +   
Sbjct: 2584 PAPKEAVREGRP-PEPTPAKRKRRSSSSSS-----SSSSSSSSSSSSSSSSSSSSSSSSS 2637

Query: 1573 HASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVP 1619
             +S+S+S   SP+  +P   G      P+  + PP        PR P
Sbjct: 2638 SSSSSSSSSSSPSPAKP---GPQALPKPASPKKPPPGERRSRSPRKP 2681



 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 201/946 (21%), Positives = 309/946 (32%), Gaps = 145/946 (15%)

Query: 312  PSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEA 371
            P   E  P  G+ PA + T   A L   E+  E L    FG+  S +  +S     Q  A
Sbjct: 105  PGGKEETP--GQRPAVTETHQLAELN--EKKNERLRAA-FGISDSYVDGSS--FDPQRRA 157

Query: 372  DTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGA-RMGPGSGPGALP 430
                QPAP    P  +  ++S    P P           G ++E  + R           
Sbjct: 158  REAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217

Query: 431  KTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRL 490
                + S K         SK  +K K   + R+  P  ++     S S  + ++  T R 
Sbjct: 218  HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277

Query: 491  QVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT 550
            +  +      T  L  ++                       P P S +       R  G 
Sbjct: 278  RSRSAAAKTHTTALAGRS-----------------------PSPASGR-------RGEGD 307

Query: 551  SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKT 610
            +P  + G     +PS P  A   P    +SP   K     K   A+ PS +P        
Sbjct: 308  APFSEPGTTSTQRPSSPETATKQP----SSPYEDK-DKDKKEKSATRPSPSPE------- 355

Query: 611  RVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYS 670
                ++   P+PP    PTP   +   G  +    TP+ +     P   EA     +   
Sbjct: 356  ----RSSTGPEPP---APTPLLAERHGGSPQPLATTPLSQEPVNPP--SEASPTRDRSPP 406

Query: 671  QDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHP-PSPSEIHKVGS 729
            +   + PQS           SSS+S        +V +  S+    P P P+P    ++ S
Sbjct: 407  KSPEKLPQS-----------SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISS 455

Query: 730  SMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAE 789
            S     ++ G A  ++S    S T   +  R  S +                     S +
Sbjct: 456  SPTSKNRSHGRAKRDKS---HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQ 512

Query: 790  WRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILE 849
            WRR R  Q    S                   G S  P +P    +  T     +R+   
Sbjct: 513  WRRSRSAQRWGRS-------------RSPQRRGRSRSPQRPGWSRSRNT-----QRRGRS 554

Query: 850  MSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPR-PEPSQEPAALPKRRLPHNATTGYEEL 908
             SA          AT GR  ++   ++G  R R P   +  +  P RR   + T      
Sbjct: 555  RSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPA---- 610

Query: 909  LPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLT 968
               G S   T          RR +T       S         G   S  R P     S +
Sbjct: 611  -RRGRSRSRTPAR-------RRSRTRSPVRRRSRSRSPARRSG--RSRSRTPARRGRSRS 660

Query: 969  GSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHR 1028
             +P  R R        + TP+  SG S +   +    S S   RR R       R+ R  
Sbjct: 661  RTPARRGRSR------SRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714

Query: 1029 SHGPLLPTIEDSSEEEELREEEELLREQEKMR-EVEQQRI---RSTARKTRRDKEELRAQ 1084
            S  P       SS E + +      R +     E+++ RI   RS +  + R K + R  
Sbjct: 715  SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLS 774

Query: 1085 RRR----------ERSKTPP------SNLSPIEDASPTEELRQAA------EMEELHRSS 1122
             RR          ++S+TPP      S+    +  +P    R ++      + +   R S
Sbjct: 775  LRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQS 834

Query: 1123 CSEYSPSPSLDSEAEALDG---GPSRLYKSGSEYNLPTFMSLYSP---TETPSGSSTTPS 1176
             S  SP P + S      G    P    +S +      F S   P   + TPS  S + S
Sbjct: 835  HSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS 894

Query: 1177 SGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPR 1222
            S   +KS+    +   R +    + +   +  +  H G S P+  R
Sbjct: 895  SPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSR 940



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 229/1182 (19%), Positives = 379/1182 (32%), Gaps = 145/1182 (12%)

Query: 19   GGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSR 78
            G +  G GP P  G+    S+P    +  +  A R +   P P       P      +S 
Sbjct: 1639 GSSSKGRGPSP-EGSSSTESSPEHPPK--SRTARRGSRSSPEPKTKSRTPPRRRSSRSSP 1695

Query: 79   RLDPKEPLGNQ-RAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQR 137
             L  K  L  + R+AS +P+  S T P H       +  PA +     RR      RT+ 
Sbjct: 1696 ELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKT 1755

Query: 138  SGRSPSVSPDRGSTPT-SPYSVPQIAPLPSSTLCPICKTSDLT-STPSQPNFNTCTQCHN 195
            + R       RG +P+  P  + +             +  D + S+ S       ++  +
Sbjct: 1756 TSR-------RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRS 1808

Query: 196  KVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPA--------L 247
            +V  +       H              +R  G   T     K  +   SPA         
Sbjct: 1809 RVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRA 1868

Query: 248  SPA---HSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSP 304
            SPA    S ++ PL    + RSR      P SR+   +R +     +++ A P   R S 
Sbjct: 1869 SPATHRRSRSRTPLISRRRSRSR----TSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSR 1924

Query: 305  QPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTL 364
                P     +  R P     ++S T  P     +      +T +      S +T+  + 
Sbjct: 1925 SRTPPVTRRRSRSRTPTTRRRSRSRTP-PVTRRRSRSRTPPVTRRRSRSRTSPITRRRSR 1983

Query: 365  MSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGP-- 422
                P    + +   S  T +   +  S     +     P   PA   ++     + P  
Sbjct: 1984 SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTP---PAIRRRSRSRTPLLPRK 2040

Query: 423  ---GSGPGALPKTGGTTSPKHGRAEHQ------AASKAAAKPKTMPKERAICPLCQAELN 473
                  P A+ +   + +P+  R +        A  + +A   +  + R+  P      +
Sbjct: 2041 RSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRN-H 2099

Query: 474  VGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPP 533
             GS++P       + R+   +    +PTP            C++  +LE      TP+  
Sbjct: 2100 SGSRTPPV--ALNSSRMSCFSRPSMSPTP---------LDRCRSPGMLEPLGSSRTPMSV 2148

Query: 534  ----------------PTSQQPPVGAPHRAS-----------GTS-PLKQKGPQGLGQPS 565
                            P  Q+  V   H  S           GT+ P       GL    
Sbjct: 2149 LQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARM 2208

Query: 566  GPLPA-------KASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEP 618
              +PA       + +P +  AS +P+ AS  A  L ++     P++V    +R P  A  
Sbjct: 2209 SQVPAPVPLMSLRTAPAANLASRIPA-ASAAAMNLASARTPAIPTAVNLADSRTPAAAAA 2267

Query: 619  MPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ 678
            M    P T   P      S V  A+P TP   AV          +L G       +R+P 
Sbjct: 2268 MNLASPRTAVAP------SAVNLADPRTPTAPAV----------NLAG-------ARTPA 2304

Query: 679  SLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQ 738
            +L+    +  G   + +       +  +   SA + GP     +    +  S      A 
Sbjct: 2305 ALAALSLTGSGTPPTAANYPS-SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAP 2363

Query: 739  GLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQD 798
                S R  P  SG      + P S         S   L+        SA  + R   + 
Sbjct: 2364 ASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSER 2423

Query: 799  TAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLE 858
                S   G       +  + +   SP+P       +  +D+           A   +L 
Sbjct: 2424 APSPSSRMGQAPSQSLLPPAQDQPRSPVP-------SAFSDQSRCLIAQTTPVAGSQSLS 2476

Query: 859  EDDTATSGRGLAKHGTQKGGPRPRPEPSQ--EPAALPKRRLPHNATTGYEELLPEGGSAE 916
                AT+      H      P P    S   EP A    + P               S+ 
Sbjct: 2477 SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 917  ATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP-------ELEMESLTG 969
            ++  S +         +    S+ S      L   P+ +L R P       E   E    
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596

Query: 970  SPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRS 1029
             P    R   SS+  +S+ S +S +S +S SS    S SS S       +     A+   
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656

Query: 1030 HG---PLLPTIEDSSEEEEL--REEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQ 1084
                 P  P      E      R+  + LR+   +     +R R + + + RD++   ++
Sbjct: 2657 QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716

Query: 1085 RRRERSKTPPSNLSPIEDASPTEELRQAAEMEE--LHRSSCS 1124
            R   R +   S        SP+ + R+         HRSS S
Sbjct: 2717 RGSRRGQRGDSR-------SPSHKRRRETPSPRPMRHRSSRS 2751



 Score = 59.7 bits (143), Expect = 6e-08
 Identities = 206/1004 (20%), Positives = 336/1004 (33%), Gaps = 147/1004 (14%)

Query: 693  SQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSER------- 745
            S S + G       +   A    P PP P  + +  SS R     Q     ++       
Sbjct: 142  SDSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSE 201

Query: 746  -----------SKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRR 794
                       SK     +  E K+R H  S TP++    ++ +         A   RR 
Sbjct: 202  SSSPRRERKKSSKKKKHRSESESKKRKHR-SPTPKSKRKSKDKKRKRSRSTTPAPKSRRA 260

Query: 795  EQQ---DTAESSDDFGSQLRHDYVE--DSSEGGLSPLPPQPPARAAELTDEDFMRRQILE 849
             +    D+A SSD   S+ R    +   ++  G SP P        +    +        
Sbjct: 261  HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320

Query: 850  MSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELL 909
             S+ E   ++  +    +   K   +K   RP P P +             ++TG E   
Sbjct: 321  PSSPETATKQPSSPYEDKD--KDKKEKSATRPSPSPER-------------SSTGPEPPA 365

Query: 910  PEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTG 969
            P    AE   GS              L +T      ++      P+ DR P    E L  
Sbjct: 366  PTPLLAERHGGSPQ-----------PLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414

Query: 970  SPEDRSRGEHSSTLPASTPSYTSGTSP---TSLSSLEEDSDSSPSRRQRLEEAKQQRKAR 1026
            S    S          S  + +S  SP    +  S  E S S  S+ +    AK+ +   
Sbjct: 415  SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474

Query: 1027 H-------RSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
            H       RS  P       +++    R      R   + R  + +R RS  R  R    
Sbjct: 475  HTPSRRMGRSRSPA------TAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRS--- 525

Query: 1080 ELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEAL 1139
              R+ +RR RS++P     P    S   + R  +      RS    +S SP+  +   + 
Sbjct: 526  --RSPQRRGRSRSPQ---RPGWSRSRNTQRRGRSRSARRGRS----HSRSPA--TRGRSR 574

Query: 1140 DGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGR-----PLKSAEEAYEEMMRK 1194
               P+R  +S S           +PT   S S T    GR     P +        + R+
Sbjct: 575  SRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRR 634

Query: 1195 AELLQ--RQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE-YGQAAQPAAEGTPAS 1251
            +      R+ G++        G S+   P   G    +    R    ++  PA  G   S
Sbjct: 635  SRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRS 694

Query: 1252 ----LGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDP-MKQN-- 1304
                 G +    +++  +S  R  Q   R  + +E K K +       +   P MK++  
Sbjct: 695  RTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRI 754

Query: 1305 --------GGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKL 1356
                      P +   S   L   +S S+P     S           +  +  +Q   K 
Sbjct: 755  SSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKS------QTPPRRSRSGSSQPKAKS 808

Query: 1357 HSSPASPSSASKEIGMPFSQGPGTPATTAVAPCP---AGLPRGYMTPASPAGSERSPSPS 1413
             + P    S+S       S+ P   + ++ +P P   +G P    +  SP  +E+S +P 
Sbjct: 809  RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQ 868

Query: 1414 STAHSYGHSPTTANYGSQTEDLPQAPSGLAAAG----RAAREKPLSASDGEGGTPQPS-- 1467
              +  +  SP         E   + PS  + +G    R     P   S     +PQP   
Sbjct: 869  RRS-CFESSP-------DPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVK 920

Query: 1468 -----RAYSYFASSSPP----LSPSSPSESPTFSP-----GKMGPRATAEFSTQTPSPAP 1513
                 R  S+  SSSP      S ++P  S + SP      ++ PR +   S+   +   
Sbjct: 921  AIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVK 980

Query: 1514 ASDMPRSPGAPTPSPMVAQGTQTPHRPS-------TPRLVWQESSQEAPFMVITLASDAS 1566
                PR   + + SP      QTP  PS        P+   ++S  ++    ++L +   
Sbjct: 981  PETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVK 1040

Query: 1567 SQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPP 1610
            S T    +    S L    ++Q +    S T+ P V Q   E P
Sbjct: 1041 SSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESP 1084



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 340/1654 (20%), Positives = 563/1654 (34%), Gaps = 261/1654 (15%)

Query: 75   STSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSR 134
            S  R+     P   +++     K++ +TTP  +S R  R+       +    R+    + 
Sbjct: 224  SKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAA 283

Query: 135  -----TQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNT 189
                 T  +GRSPS +  R     +P+S P      +ST  P       T  PS P  + 
Sbjct: 284  AKTHTTALAGRSPSPASGRRGEGDAPFSEPG----TTSTQRP-SSPETATKQPSSPYEDK 338

Query: 190  CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPA-LS 248
                  K   +   +P    T  +         +R  G     A    SQ+ ++ P+  S
Sbjct: 339  DKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEAS 398

Query: 249  PA--HSPAKQPLGKPDQERSR-GPGGPQPG--SRQAETARATSVPGPA-----QAAAPP- 297
            P    SP K P   P    S   P  PQP   SR A ++  +  P PA     + ++ P 
Sbjct: 399  PTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPT 458

Query: 298  ----EVGRVSPQPPQPTKPS--TAEPRPPAGEAPAKSATAVPAGLG----ATEQTQEGLT 347
                  GR          PS      R PA     +S +  P   G     + Q +   +
Sbjct: 459  SKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518

Query: 348  GKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPG 407
             + +G   S   +  +  S Q    ++ +    +G  +      S    P   G      
Sbjct: 519  AQRWGRSRSPQRRGRS-RSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRT 577

Query: 408  PA--PGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAIC 465
            PA    +++   AR    S      ++   T  + GR+  +  ++  ++ ++  + R+  
Sbjct: 578  PARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRS-- 635

Query: 466  PLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSL 525
                      S+SPA  +  +  R         + TP    ++       +T     G  
Sbjct: 636  ---------RSRSPARRSGRSRSRTPARRGRSRSRTPARRGRS-----RSRTPARRSGRS 681

Query: 526  GEPTPLPPPTSQQPPVGAPHRA-SGTSPLKQKG------PQGLGQPSGPLPAKASPLSTK 578
               TP     S+      P R  S +  L ++G      PQ  G+ SG    + +   T 
Sbjct: 682  RSRTPARRGRSRS---RTPRRGRSRSRSLVRRGRSHSRTPQRRGR-SGSSSERKNKSRTS 737

Query: 579  ASPLPSKASPQAKPLR-ASEPSKTPSSVQEK-KTRVPTK-----AEPMPKPPPETTPTPA 631
                 S +SP+ K  R +S  S++ SS + K K+R+  +     + P PK   +T P  +
Sbjct: 738  QRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRS 797

Query: 632  TPKVKSGVRRAEPATPVVKA-VPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGI 690
              +  S   +A+  TP  ++    +P   +      +     +S  P+  S T      I
Sbjct: 798  --RSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSI 855

Query: 691  SSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLS 750
            +S Q+    V  Q     +S+        +PS  H    S  P +++    P  +S   S
Sbjct: 856  TSPQANEQSVTPQRRSCFESSPDPELKSRTPSR-HSCSGSSPPRVKSS--TPPRQSPSRS 912

Query: 751  SGTGEEQK------QRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSD 804
            S    + K      QR HS S +P                      R    +  +     
Sbjct: 913  SSPQPKVKAIISPRQRSHSGSSSP---------------SPSRVTSRTTPRRSRSVSPCS 957

Query: 805  DFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTAT 864
            +  S+L   Y    S    + + P+ P R +                             
Sbjct: 958  NVESRLLPRYSHSGSSSPDTKVKPETPPRQSH---------------------------- 989

Query: 865  SGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTL 924
            SG  ++ +   K    P P  S   +  P+ +   +        L      +++   G  
Sbjct: 990  SG-SISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGES 1048

Query: 925  QGGLRRFKTIELNSTGSYGHELDLGQGPD--PSLDREPELEMESLTGSPEDRSRGEHSST 982
              G+   + ++  S  S  H  D    P+   S    P L+ +S T     RSR     T
Sbjct: 1049 YFGVSSLQ-LKGQSQTSPDHRSDT-SSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVT 1106

Query: 983  LPAS-------------TPSYTSGTSPTSLSSLEEDSDSSPS-------RRQRLEEAKQQ 1022
              AS             +P   SG SP   S  + DS S P+        + RLE A+ +
Sbjct: 1107 ELASRSPIRQDRGEFSASPMLKSGMSPEQ-SRFQSDSSSYPTVDSNSLLGQSRLETAESK 1165

Query: 1023 RKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEEL- 1081
             K         LP  ED++     R++++      + R       + T R   R++    
Sbjct: 1166 EKM-------ALPPQEDATASPP-RQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAG 1217

Query: 1082 RAQRRRERSKTPPSNLSPIEDASPTEELRQAAEM------EELHRSSCSEYSPSPSLDSE 1135
             +   +E++   P++    E     E+  + A         EL   S S +  SP    E
Sbjct: 1218 SSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSP----E 1273

Query: 1136 AEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKA 1195
             E        L +S S+ +L          E PS +S   S G P  S E    + +  +
Sbjct: 1274 VEERPAVSLTLDQSQSQASL-------EAVEVPSMAS---SWGGPHFSPE---HKELSNS 1320

Query: 1196 ELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQ-AAQPAAEGTPASLGA 1254
             L +   G     R  + GP       G  S   +D       Q    P+ +    S  +
Sbjct: 1321 PLRENSFGSPLEFR--NSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRS 1378

Query: 1255 AVYEEILQTSQSIVRMRQASSRDLAF-AEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTS 1313
            + +     +  ++ +   +S++ ++    D           S+   P  ++G P TP   
Sbjct: 1379 SGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRR 1438

Query: 1314 PTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEI-GM 1372
                    S S+P   D SG         ++H    +   +K    P +PS    E    
Sbjct: 1439 SR------SGSSPGLRDGSG-------TPSRHSLSGSSPGMK--DIPRTPSRGRSECDSS 1483

Query: 1373 PFSQG-PGTPATTAVAPCPAGLPRGYMTP-ASPAGSERSPSPSSTAHSYGHSPTTANYGS 1430
            P  +  P TP   + +P    L    +TP    +GSE S    + A +     + +    
Sbjct: 1484 PEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQ 1543

Query: 1431 QTEDLPQA------PSGLAAAGRAAREKPLSASDGEGGTPQ--------PSRAYSYFASS 1476
            + +  P A       S  +   +A    PL      G +P+        P R+ S    S
Sbjct: 1544 ELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRS---GS 1600

Query: 1477 SP---------PLSPSSPSESPTFSPGKMGPRATAEFST-------QTPSPAPASDMPRS 1520
            SP         P + S    SP   P    PRA    S        + PSP  +S    S
Sbjct: 1601 SPEVKDKPRAAPRAQSGSDSSP--EPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESS 1658

Query: 1521 PGAPTPSPMVAQGTQTPHRPST-----PRLVWQESSQEAPFMVITLASDASSQTRMVHAS 1575
            P  P  S    +G+++   P T     PR   + SS+ +P   +T  +  S ++R    S
Sbjct: 1659 PEHPPKSRTARRGSRSSPEPKTKSRTPPR---RRSSRSSP--ELTRKARLSRRSR----S 1709

Query: 1576 ASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEP 1609
            AS+SP        P  H  S    PSVS   PEP
Sbjct: 1710 ASSSP--ETRSRTPPRHRRS----PSVSS--PEP 1735



 Score = 57.8 bits (138), Expect = 2e-07
 Identities = 261/1244 (20%), Positives = 422/1244 (33%), Gaps = 191/1244 (15%)

Query: 2292 GAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSR 2351
            G+G PSR  +   +   + +P T      E   +P P  L     P   +P       S 
Sbjct: 1450 GSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSP-------SS 1502

Query: 2352 PGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLL 2411
            P    +  + +  +   +  + Q    R  L +  +    +EL+ +     + R E    
Sbjct: 1503 PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESD-- 1560

Query: 2412 VQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQ-----QQL 2466
                  + +      L+Q+     +     + +L+ +R +     +++ + +     Q  
Sbjct: 1561 ---SSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSG 1617

Query: 2467 EEQKQRQKAPFPAAC--------EAPGRGPPLAAAELAQNGQYWPPLTHAAFI-AMAGPE 2517
             +     KAP P A          + GRGP    +   ++    PP +  A   + + PE
Sbjct: 1618 SDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPE 1677

Query: 2518 GLGQPREPVLHRGLPSSA--SDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPC 2575
               + R P   R   SS   +  +  +     AS S   +  + PR R +  + S  EP 
Sbjct: 1678 PKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSS-PEPA 1736

Query: 2576 VV------RRIADSS-VQTDDEDGES-----RYLLSRRRRARRSADCSVQTDDEDSAEWE 2623
                    RR A S   +T    G S     R L   R R+RR    + +  D   +   
Sbjct: 1737 EKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQS 1796

Query: 2624 QPVRRRRSRLP------RHSDSGSDSKHDATASSSSAAATVRAMSSVGIQTISDCS-VQT 2676
               RR+RSR        R   SG  S+  A   SS  ++  R   S    T    S  +T
Sbjct: 1797 TSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRT 1856

Query: 2677 EPD----QLPRVSPAIHITAAT-DPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAG 2731
             P        R SPA H  + +  P +   R  S      R  S +  +    +++  A 
Sbjct: 1857 SPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRAS 1916

Query: 2732 PQLVGPTAISPYLPGI-----QIVTPGPLGRFEKKKPDPLEIGYQAHLPPESLSQLVSRQ 2786
            P  V         P +     +  TP    R   + P       ++  PP +  +  SR 
Sbjct: 1917 P--VSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRT 1974

Query: 2787 PPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSP----QKHFTADSALRQQT---- 2838
             P + +   S  SP++  R    +   + R +++  SP    +       A+R+++    
Sbjct: 1975 SPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRT 2034

Query: 2839 --LPR-------PMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQV----SALP 2885
              LPR       P+   +RS S   P +   + S        + +   GS      SA P
Sbjct: 2035 PLLPRKRSRSRSPLAIRRRSRS-RTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATP 2093

Query: 2886 PNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASL---LQRGLTGPTTVPATKASLLR 2942
            P +      RT   PP       ++  + P +    L      G+  P     T  S+L+
Sbjct: 2094 PATRNHSGSRT---PPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQ 2150

Query: 2943 ELDRDL------RLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGG 2996
            +    +      R+ +H+ T + +  A     +  I   L  + LG  +   S++     
Sbjct: 2151 QAGGSMMDGPGPRIPDHQRTSVPENHA-----QSRIALALTAISLGTARPPPSMS----- 2200

Query: 2997 RDYPPLRGLGEHRDYL-SDSELNQLRLQGCTTPAGQFVD-FPATAAA------PATPSGP 3048
                   GL      + +   L  LR    T PA       PA +AA        TP+ P
Sbjct: 2201 -----AAGLAARMSQVPAPVPLMSLR----TAPAANLASRIPAASAAAMNLASARTPAIP 2251

Query: 3049 TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFP-PGASYPAE---- 3103
            TA      + PA   +     P     P+  A     P T  APA    GA  PA     
Sbjct: 2252 TAVNLADSRTPAAAAAMNLASPRTAVAPS--AVNLADPRTPTAPAVNLAGARTPAALAAL 2309

Query: 3104 ----PGLPNQQAFRPTGHYAGQTPM-PTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVP 3158
                 G P   A  P+   + +TP  P + + + P  A + AP+      + A L     
Sbjct: 2310 SLTGSGTPPTAANYPS---SSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASL 2366

Query: 3159 TNYEV--------IASPVVPMS-----------------------SAPSE---TSYSGPA 3184
            T+  +        + SP VP+S                       SAPS+   TS   P+
Sbjct: 2367 TSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPS 2426

Query: 3185 VSSGYEQGKVPE---VPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISE-L 3240
             SS    G+ P    +P A D+    +SP P+  SD     + Q  P        +S   
Sbjct: 2427 PSS--RMGQAPSQSLLPPAQDQ---PRSPVPSAFSDQSRCLIAQTTP--VAGSQSLSSGA 2479

Query: 3241 TKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRG 3300
               +TS+A D   +  L   + G P  + GEP    G   P   A  +   E  S     
Sbjct: 2480 VATTTSSAGDHNGM--LSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSS 2537

Query: 3301 KGGHLRSMESNGRPASTHYYGDSDYRHGARVE-------KYGPGPM-GPKHPSKSLAPAA 3352
                  S  S+   +S+     S    G+ +        K  P P   PK   +   P  
Sbjct: 2538 SSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE 2597

Query: 3353 ISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSS 3396
             +  + K R        S  S    +    S  +S    + SSS
Sbjct: 2598 PTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2641



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 334/1707 (19%), Positives = 565/1707 (33%), Gaps = 232/1707 (13%)

Query: 2245 PMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPE-MPV 2303
            P++A R    P  L   P  S+ P+    PP+E       P   ++P    P  PE +P 
Sbjct: 368  PLLAERHGGSPQPLATTPL-SQEPVN---PPSEA-----SPTRDRSP----PKSPEKLPQ 414

Query: 2304 GAAREEPLPTTTPAAIKEAAGA----PAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEA 2359
             ++ E   P+  P  +   A +    P PAP  G      ++P   + +  R   +K  +
Sbjct: 415  SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHS 474

Query: 2360 SQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQR-HREEEQLLVQRELQE 2418
                R+  +       +R R                R R   +R H        +R    
Sbjct: 475  HTPSRRMGRSRSPATAKRGR---------------SRSRTPTKRGHSRSRSPQWRRSRSA 519

Query: 2419 LQTIKHHVLQQQQEERQAQF-ALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPF 2477
             +  +    Q++   R  Q     R +  Q+R +    ++ +   +      + R + P 
Sbjct: 520  QRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPA 579

Query: 2478 P---AACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLGQPREPVLHRGLPSS 2534
                +    P R    +     +  +   P       +        + R PV  R    S
Sbjct: 580  RRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRS 639

Query: 2535 ASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRIADSSVQTDDEDGES 2594
             +  S ++  +  A R   + R    R R      +       RR   S  +T    G S
Sbjct: 640  PARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPA-------RRSGRSRSRTPARRGRS 692

Query: 2595 RYLLSRRRRAR--------RSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSDSGSDSKHD 2646
            R    RR R+R        RS   + Q      +  E+  + R S+    S+S  + K  
Sbjct: 693  RSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKS 752

Query: 2647 ATASSSSAAATVRAMSSVGIQTISDCSVQTE-------PDQLPRVSPAIHITAATDPKVE 2699
              +S  S     R++SS   +  S  S++         P Q  +  P    + ++ PK  
Sbjct: 753  RISSRRS-----RSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPK-- 805

Query: 2700 IVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFE 2759
                  A  +T    S +  + P  Q      P     ++ SP+ P ++  TP   G   
Sbjct: 806  ------AKSRTPPRRSRSSSSPPPKQKSKT--PSRQSHSSSSPH-PKVKSGTPPRQGSIT 856

Query: 2760 KKKPDPLEIGYQAHLPPESLS--QLVSRQPPKSPQVLYSP--VSPLSPHRLLDTSFASSE 2815
              + +   +  Q     ES    +L SR P +      SP  V   +P R   +  +S +
Sbjct: 857  SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ 916

Query: 2816 RLNKAHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQG 2875
               KA +SP++   + S+    +      T +RS S    +SP +   ++     Y H G
Sbjct: 917  PKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS----VSPCSNVESR-LLPRYSHSG 971

Query: 2876 GLGSQVSALPPNSLVRKVKRTLPSPPPEEAHLP----LAGQASP-----------QLYAA 2920
                     P     +    ++   P  +A  P    L+G  SP           Q    
Sbjct: 972  SSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPG 1031

Query: 2921 SLLQRGLTGPTTVPATK---ASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLK 2977
            SL        +T P       S L+   +     +H S     +  +   E   + +K +
Sbjct: 1032 SLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQ 1091

Query: 2978 YLELGITQRKES----------LAKDRGGRDYPPLRGLG---EHRDYLSDSE-------- 3016
                G   R  S          + +DRG     P+   G   E   + SDS         
Sbjct: 1092 TSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSN 1151

Query: 3017 --LNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSG---GPT 3071
              L Q RL+  T  + + +  P    A A+P      Q+ +F P   Q    S      T
Sbjct: 1152 SLLGQSRLE--TAESKEKMALPPQEDATASPPR----QKDKFSPFPVQDRPESSLVFKDT 1205

Query: 3072 QNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTG----HYAGQTP-MPT 3126
                P  ++     P T    +  P +S   E     +++  P G    H + +   M T
Sbjct: 1206 LRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMST 1265

Query: 3127 TQSTLFPV----PADSRAPLQKPRQTSLADLEQKV-----------PTNYEVIASPVVPM 3171
            +     P     PA S    Q   Q SL  +E              P + E+  SP+   
Sbjct: 1266 SNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLREN 1325

Query: 3172 S-SAPSETSYSGPA---VSSGY----------------EQGKVPEVPRAGDRGSVSQSPA 3211
            S  +P E   SGP    +++G+                E     ++     R S   S +
Sbjct: 1326 SFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS-GHSSS 1384

Query: 3212 PTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGE 3271
               P       +  N   +  ++D +        S++  S  ++   P +  R  +    
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444

Query: 3272 PGVLDGPTLPCCYA-RGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGAR 3330
            PG+ DG   P  ++  G     +D   PR         +S+  P +         R    
Sbjct: 1445 PGLRDGSGTPSRHSLSGSSPGMKDI--PRTPSRGRSECDSSPEPKALPQTPRPRSR---- 1498

Query: 3331 VEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPP 3390
                   P  P+  +K L P     +     +  ++QK    +P+ +     S       
Sbjct: 1499 ------SPSSPELNNKCLTP----QRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVK 1548

Query: 3391 PAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRS------- 3443
            P+ S    S      D      K     +Q+    SS +     R+    SRS       
Sbjct: 1549 PSASPQERSESDSSPDS---KAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK 1605

Query: 3444 ----RAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRS 3499
                 AP A SG   S    +   +   R   +    +  GP P   S   S    P +S
Sbjct: 1606 DKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665

Query: 3500 QASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAH-AYKREEG 3558
            + +   S  SP  + +           T P+  SS S P++    +   R+  A    E 
Sbjct: 1666 RTARRGSRSSPEPKTK---------SRTPPRRRSSRSSPELTRKARLSRRSRSASSSPET 1716

Query: 3559 YILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYH 3618
                      S S +     E++    + R A S R +       S S + RG  R    
Sbjct: 1717 RSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSR 1776

Query: 3619 DYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHE 3678
               E         D  G  +  S +  R     R + R  G   G  +  P  ++  R  
Sbjct: 1777 SRREKTRT-TRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS-GYHSRSPARQESSRTS 1834

Query: 3679 ARPHSQPSSAPAMPKKGQPGYPSSAEYSQP-SRASSAYHHASD------SKKGSRQAHSG 3731
            +R     S  P   +K      S A + +  SRAS A H  S       S++ SR   S 
Sbjct: 1835 SRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSP 1894

Query: 3732 PAALQSKAEPQAQPQLQGRQAAP-GPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPP 3790
             +  +S++      +    +A+P   ++S+S +       + SR P T+++ +     PP
Sbjct: 1895 VSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSR--SRTPP 1952

Query: 3791 QQALTQARLQQQSQPTTRGSAPAASQP 3817
               +T+ R + ++ P TR  + + + P
Sbjct: 1953 ---VTRRRSRSRTPPVTRRRSRSRTSP 1976



 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 60/269 (22%), Positives = 103/269 (38%), Gaps = 18/269 (6%)

Query: 3630 PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAP 3689
            P  + G  R  S +       G   G  T        + P  +D+ R  +R  S+  S+P
Sbjct: 1425 PEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSP 1484

Query: 3690 ---AMPKKGQPGY--PSSAEYSQ----PSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
               A+P+  +P    PSS E +     P R  S    + D K  +R        L  ++ 
Sbjct: 1485 EPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVAR------TPLGQRSR 1538

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQA-LTQARL 3799
              +  +L  + +A   ++S+S SS    S A +R P  Q+ + G   +   ++ L+  R 
Sbjct: 1539 SGSSQELDVKPSASPQERSESDSSPD--SKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRS 1596

Query: 3800 QQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQ 3859
            +  S P  +    AA +        P        A P R+   + SKG   +P+   + +
Sbjct: 1597 RSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTE 1656

Query: 3860 AQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            + P   P     + G+R    P   +  P
Sbjct: 1657 SSPEHPPKSRTARRGSRSSPEPKTKSRTP 1685



 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 213/1039 (20%), Positives = 337/1039 (32%), Gaps = 166/1039 (15%)

Query: 581  PLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVK---- 636
            P P    P +  +R S  S++P+  Q+KK +   +        P      ++ K K    
Sbjct: 163  PAPEPPKPYSL-VRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSE 221

Query: 637  --SGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ----SLSDTGYSSDGI 690
              S  R+    TP  K   +  K   +      P S+ A RS      S SDT  S    
Sbjct: 222  SESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRS 281

Query: 691  SSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLS 750
            +++++  T +  +               PSP+   +           +G AP        
Sbjct: 282  AAAKTHTTALAGRS--------------PSPASGRR----------GEGDAPF------- 310

Query: 751  SGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGSQL 810
            S  G    QRP S     +   S  E     ++D+D  E    R       SS       
Sbjct: 311  SEPGTTSTQRPSSPETATKQPSSPYE-----DKDKDKKEKSATRPSPSPERSSTGPEPPA 365

Query: 811  RHDYVEDSSEGGLSPL--------PPQPPARAAELTDEDFMRR-QILEMSAEEDNLEEDD 861
                + +   G   PL        P  PP+ A+   D    +  + L  S+  ++     
Sbjct: 366  PTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSP 425

Query: 862  TATSGRGLAKHGTQKGGPRPRPEPSQEPAALP--KRRLPHNATTGYEELLPEGGSAEATD 919
              T     A    +   P P P   +E ++ P  K R    A                + 
Sbjct: 426  QPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSR 485

Query: 920  GSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEH 979
               T + G  R +T         GH     +   P   R    +    + SP+ R R   
Sbjct: 486  SPATAKRGRSRSRT-----PTKRGHS----RSRSPQWRRSRSAQRWGRSRSPQRRGRSR- 535

Query: 980  SSTLPASTPSYTSGTSPTSLSSLEEDSDS-SPSRRQRLEEAKQQRKARHRSHGPL----- 1033
            S   P  + S  +     S S+    S S SP+ R R       R+ R RS  P      
Sbjct: 536  SPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR 595

Query: 1034 --LPTIEDSSEEEELREEEELLREQEKMREV------EQQRIRSTARKTRRDKEELRAQR 1085
               PT   S      R      R   + R         + R RS AR++ R +    A+R
Sbjct: 596  SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARR 655

Query: 1086 RRERSKTP-----PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALD 1140
             R RS+TP       + +P   +  +     A       R+     S S SL     +  
Sbjct: 656  GRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHS 715

Query: 1141 GGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQR 1200
              P R  +SGS             +E  + S T+    R   S E      M+K+ +  R
Sbjct: 716  RTPQRRGRSGSS------------SERKNKSRTSQRRSRSNSSPE------MKKSRISSR 757

Query: 1201 QQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEG-TPASLGAAVYEE 1259
            +    +  R      S+ +  R L             G +  P  +  TP     +   +
Sbjct: 758  RSRSLSSPRSK--AKSRLSLRRSLS------------GSSPCPKQKSQTPPRRSRSGSSQ 803

Query: 1260 ILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPG--TSPTQL 1317
                S++  R  ++SS      + K   +Q  ++ S +  P  ++G P   G  TSP   
Sbjct: 804  PKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPH--PKVKSGTPPRQGSITSPQAN 861

Query: 1318 AAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSP--------ASPSSASKE 1369
               V+    +  +SS    +     ++H    +  P    S+P        +SP    K 
Sbjct: 862  EQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKA 921

Query: 1370 IGMPFSQ---GPGTPA------------TTAVAPC----PAGLPR-GYMTPASPAGSERS 1409
            I  P  +   G  +P+            + +V+PC       LPR  +   +SP    + 
Sbjct: 922  IISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKP 981

Query: 1410 PSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREK---------PLSASDGE 1460
             +P   +HS   SP    Y       P  PS   +     +EK         P S S   
Sbjct: 982  ETPPRQSHSGSISP----YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCA 1037

Query: 1461 GGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRS 1520
            G         SYF  SS  L   S + SP        P      S      + +   P+ 
Sbjct: 1038 GVKSSTPPGESYFGVSSLQLKGQSQT-SPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKG 1096

Query: 1521 PGAPTPSPMVAQGTQTPHR 1539
              + + SP+    +++P R
Sbjct: 1097 GRSRSSSPVTELASRSPIR 1115



 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 60/274 (21%), Positives = 104/274 (37%), Gaps = 28/274 (10%)

Query: 3632 DEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAM 3691
            D G     +S +  R     +   R   E   R+   P  +   + + +   +  S    
Sbjct: 195  DRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPA 254

Query: 3692 PKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQ 3751
            PK  +    +SA+      ASS+    S S+  + + H+   A +S + P +  + +G  
Sbjct: 255  PKSRRAHRSTSAD-----SASSSDTSRSRSRSAAAKTHTTALAGRSPS-PASGRRGEGDA 308

Query: 3752 --AAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRG 3809
              + PG   +Q PSS +     A++QP +  + +       ++  +  R     + ++ G
Sbjct: 309  PFSEPGTTSTQRPSSPE----TATKQPSSPYEDK----DKDKKEKSATRPSPSPERSSTG 360

Query: 3810 SAPAASQP------AGKPQPGPSTATGPQPAGPPR----AEQTNGSKGTAKAPQQGRAPQ 3859
              P A  P       G PQP  +T    +P  PP         +  K   K PQ   +  
Sbjct: 361  PEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSES 420

Query: 3860 AQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGE 3893
            + P+P P      A + P     APA  PG+  E
Sbjct: 421  SPPSPQPTKVSRHASSSPESPKPAPA--PGSHRE 452



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 175/918 (19%), Positives = 304/918 (33%), Gaps = 105/918 (11%)

Query: 754  GEEQKQRPHSLSI---TPEAFDSDE---------ELEDILEEDEDSAEWRRRREQQDTAE 801
            GEE+ +R  +  +    P+  D +          ELE+++EE        +  E+Q   E
Sbjct: 38   GEEELRRLEAALVKRPNPDILDHERKRRVELRCLELEEMMEE--------QGYEEQQIQE 89

Query: 802  SSDDFGSQLRHDYVEDSSEGGLSPLPPQPPA-----RAAELTDEDFMR-RQILEMSAEED 855
                F   L     +D + GG    P Q PA     + AEL ++   R R    +S    
Sbjct: 90   KVATFRLMLLE---KDVNPGGKEETPGQRPAVTETHQLAELNEKKNERLRAAFGIS---- 142

Query: 856  NLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSA 915
                 D+   G         +   +P PEP +  + + +     + T   ++   +    
Sbjct: 143  -----DSYVDGSSFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRG 197

Query: 916  EATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRS 975
              ++ S   +   +  K  +  S             P      + +    S + +P  +S
Sbjct: 198  RRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKS 257

Query: 976  RGEHSSTLPASTPSYT-------SGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHR 1028
            R  H ST   S  S         S  + T  ++L   S S  S R+   +A         
Sbjct: 258  RRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTS 317

Query: 1029 SHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRR-- 1086
            +  P  P            ++++  +E+   R        ST  +       L A+R   
Sbjct: 318  TQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTP-LLAERHGG 376

Query: 1087 --RERSKTPPSN--LSPIEDASPTEELRQAAEMEELHRSSCSEYSP-SPS---LDSEAEA 1138
              +  + TP S   ++P  +ASPT +       E+L +SS SE SP SP    +   A +
Sbjct: 377  SPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASS 436

Query: 1139 LDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELL 1198
                P      GS   + +     SPT      S   S GR  +    ++    R     
Sbjct: 437  SPESPKPAPAPGSHREISS-----SPT------SKNRSHGRAKRDKSHSHTPSRRMGR-- 483

Query: 1199 QRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYE 1258
             R    A   R     P++    R       +  + + +G++  P   G   S     + 
Sbjct: 484  SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGW- 542

Query: 1259 EILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLA 1318
                 S+S    R+  SR         +         +     +      TP    ++  
Sbjct: 543  -----SRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSR 597

Query: 1319 APVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGP 1378
             P    + + + +  GR     R        T+ P++  S   SP+  S   G   S+ P
Sbjct: 598  TPTRRRSRSRTPARRGR--SRSRTPARRRSRTRSPVRRRSRSRSPARRS---GRSRSRTP 652

Query: 1379 GTPATT-AVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQT----- 1432
                 + +  P   G  R   TPA  +G  RS +P+    S   +P      S++     
Sbjct: 653  ARRGRSRSRTPARRGRSRS-RTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRG 711

Query: 1433 EDLPQAPSGLAAAGRAAREKPLSASDGE----GGTPQPSRAYSYFASSSPPLSPSSPSES 1488
                + P     +G ++  K  S +         +P+  ++      S    SP S ++S
Sbjct: 712  RSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKS 771

Query: 1489 P-TFSPGKMGPRATAEFSTQTP---------SPAPASDMPRSPGAPTPSPMVAQGTQTP- 1537
              +      G     +  +QTP          P   S  P      + SP   Q ++TP 
Sbjct: 772  RLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPS 831

Query: 1538 ---HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGY 1594
               H  S+P    +  +      + +  ++  S T    +   +SP        P+ H  
Sbjct: 832  RQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSC 891

Query: 1595 SQTTPPSVSQLPPEPPGP 1612
            S ++PP V    P    P
Sbjct: 892  SGSSPPRVKSSTPPRQSP 909



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 54/232 (23%), Positives = 93/232 (40%), Gaps = 30/232 (12%)

Query: 3651 GRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA-----PAMPKKGQPGYPSSAEY 3705
            G H+G  +   PG     PH+ D+G   A   +Q  SA     PA  ++      SS+  
Sbjct: 2488 GDHNGMLSVPAPG----VPHS-DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSS 2542

Query: 3706 SQPSRASSAYHHASDSKKGSRQAHSGPA----ALQSKAEPQAQPQ---LQGRQAAPGPQQ 3758
            S  S +SS+   +S S     +  S P     AL+    P   P+    +GR   P P +
Sbjct: 2543 SSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAK 2602

Query: 3759 SQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPA 3818
             +  SS    S ++S    +              + + +     S  ++  S+P+ ++P 
Sbjct: 2603 RKRRSSSSSSSSSSSSSSSSSSSSSS-------SSSSSSSSSSSSSSSSSSSSPSPAKPG 2655

Query: 3819 GKPQPGPSTATGPQP----AGPPR--AEQTNGSKGTAKAPQQGRAPQAQPAP 3864
             +  P P++   P P    +  PR   +    S+  + +P + R P  QP+P
Sbjct: 2656 PQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP 2707



 Score = 49.7 bits (117), Expect = 6e-05
 Identities = 88/446 (19%), Positives = 144/446 (32%), Gaps = 54/446 (12%)

Query: 266  SRGPGGPQP----GSRQAETARATSVPGPAQAAAPPEVGRVSPQ-PPQPTKPSTAEPRPP 320
            SR P  P      G R A      ++ G   AAA       S +  P  +  +   PR P
Sbjct: 2327 SRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP 2386

Query: 321  AGEAPAKSATAVPAGLGATEQ-------TQEGLTGKLFGLGASLLTQASTLMSVQPEADT 373
                   S    P  L            +Q  +T +     +S + QA +   + P  D 
Sbjct: 2387 LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQ 2446

Query: 374  QGQPAPS--KGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGP----- 426
               P PS      + +    +  AG + L SG        A    G    P  G      
Sbjct: 2447 PRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDV 2506

Query: 427  GALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCT 486
            G  P + G   P    A   A  + ++   +     +      +  +  S S ++ +  +
Sbjct: 2507 GEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS 2566

Query: 487  TCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHR 546
            +  +Q        P+P    K          + + EG   EPTP      ++    +   
Sbjct: 2567 SLPVQPEVALKRVPSPTPAPK----------EAVREGRPPEPTPAK--RKRRSSSSSSSS 2614

Query: 547  ASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQ 606
            +S +S             S    + +S  S+ +SP P+K  PQA P  AS     P   +
Sbjct: 2615 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERR 2674

Query: 607  EKKTRVP---------------TKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKA 651
             +  R P                +  P P+P P    + ++ +     +R +  +P  K 
Sbjct: 2675 SRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKR 2734

Query: 652  VPEAPKGGEAEDLVGKPYSQDASRSP 677
              E P          +P    +SRSP
Sbjct: 2735 RRETPS--------PRPMRHRSSRSP 2752



 Score = 49.3 bits (116), Expect = 8e-05
 Identities = 63/260 (24%), Positives = 86/260 (33%), Gaps = 35/260 (13%)

Query: 3641 SAKEHRHGDHGRHSGRHTGEEPGRRAA-KPHARDLGRHEARPHS-------QPSSAPAMP 3692
            S + HR       S   T     R AA K H   L      P S        P S P   
Sbjct: 257  SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT 316

Query: 3693 KKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKA--EPQAQPQLQGR 3750
               +P  P +A   QPS   S Y      KK        P+  +S    EP A   L   
Sbjct: 317  STQRPSSPETAT-KQPS---SPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAE 372

Query: 3751 QAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGS 3810
            +    PQ   +    Q P    S    T+ +       PP+        ++  Q ++  S
Sbjct: 373  RHGGSPQPLATTPLSQEPVNPPSEASPTRDRS------PPKSP------EKLPQSSSSES 420

Query: 3811 APAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRA---------PQAQ 3861
            +P + QP    +   S+   P+PA  P + +   S  T+K    GRA         P  +
Sbjct: 421  SPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRR 480

Query: 3862 PAPGPGPAGVKAGARPGGTP 3881
                  PA  K G     TP
Sbjct: 481  MGRSRSPATAKRGRSRSRTP 500



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 194/981 (19%), Positives = 313/981 (31%), Gaps = 125/981 (12%)

Query: 2930 PTTVPATKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKES 2989
            P   P    SL+RE          +  K +KK      E      + K        R ES
Sbjct: 163  PAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSES 222

Query: 2990 LAKDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPT 3049
             +K R  R   P     + +    D +  + R    TTPA +      + +A +  S  T
Sbjct: 223  ESKKRKHRSPTP-----KSKRKSKDKKRKRSR---STTPAPKSRRAHRSTSADSASSSDT 274

Query: 3050 AFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQ 3109
            +  + R        +A +G           +P         AP   PG +    P  P  
Sbjct: 275  SRSRSRSAAAKTHTTALAG--------RSPSPASGRRGEGDAPFSEPGTTSTQRPSSPET 326

Query: 3110 QAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPL--QKPRQTSLADLEQKVPTNYEVIASP 3167
               +P+  Y  +      +S   P P+  R+    + P  T L  L ++   + + +A+ 
Sbjct: 327  ATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPL--LAERHGGSPQPLAT- 383

Query: 3168 VVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQS--PAPTYPSDSHYTSLEQ 3225
              P+S  P     + P+ +S       P+ P    + S S+S  P+P     S + S   
Sbjct: 384  -TPLSQEP----VNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSP 438

Query: 3226 NVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYA 3285
              P+         E++   TS      R +      S  P +  G          P    
Sbjct: 439  ESPKPAPAPGSHREISSSPTSKNRSHGRAKR-DKSHSHTPSRRMGRS------RSPATAK 491

Query: 3286 RGEEESEEDSYDPRGKGGHLRSMESNGRPA-STHYYGDS--DYRHGARVEKYGPGPMGPK 3342
            RG   S   +     K GH RS     R + S   +G S    R G       PG    +
Sbjct: 492  RGRSRSRTPT-----KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSR 546

Query: 3343 HPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGR 3402
            +  +     +    RS  R      +    +P    +      +  P    S S     R
Sbjct: 547  NTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRS----RSRTPARRRSRSRTPTRR 602

Query: 3403 KFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGW 3462
            + +        ++           +R  V         SRSR+P+  SG   S       
Sbjct: 603  RSRSRTPARRGRSRSRTPARRRSRTRSPVRR------RSRSRSPARRSGRSRSRTPAR-- 654

Query: 3463 GKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLP 3522
             +G  R R    R +     P+  S   SR R P R   S   +P     R R       
Sbjct: 655  -RGRSRSRTPARRGRSRSRTPARRS-GRSRSRTPARRGRSRSRTPRRGRSRSR------- 705

Query: 3523 PGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETD 3582
                +  +   SHS    Q   + G  +    +              + +   +    + 
Sbjct: 706  ----SLVRRGRSHSRTP-QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSR 760

Query: 3583 WFDKPRDARSDRF---RHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRH 3639
                PR     R    R   G +     + + P R S     +P  +   P     P R 
Sbjct: 761  SLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTP-----PRR- 814

Query: 3640 ASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGY 3699
                            R +   P ++ +K  +R      + PH +  S    P++G    
Sbjct: 815  ---------------SRSSSSPPPKQKSKTPSRQ-SHSSSSPHPKVKSGTP-PRQGSITS 857

Query: 3700 PSSAEYSQPSRASSAYHHASD----SKKGSRQAHSG--PAALQSKAEPQAQPQLQGRQAA 3753
            P + E S   +  S +  + D    S+  SR + SG  P  ++S   P+  P    R ++
Sbjct: 858  PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPS---RSSS 914

Query: 3754 PGP---------QQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQ 3804
            P P         Q+S S SS   PS   SR    + +          + L +      S 
Sbjct: 915  PQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSS 974

Query: 3805 PTTRGSAPAASQPAGKPQPGPSTATGPQP---AGPPRAEQTNGSKGTAKAPQQGRAPQAQ 3861
            P T+       +P   P+   S +  P P   A  P     +GSK  +  PQ+ ++  + 
Sbjct: 975  PDTK------VKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK--SPCPQE-KSKDSL 1025

Query: 3862 PAPGPGPAGVKAGARPGGTPG 3882
                PG   + AG +    PG
Sbjct: 1026 VQSCPGSLSLCAGVKSSTPPG 1046



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 89/431 (20%), Positives = 159/431 (36%), Gaps = 49/431 (11%)

Query: 3467 EREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPV-------SPLGRPRPAGG 3519
            E   +AVE+   +  +  S  +  +  R P R ++S   SP        +P  R R    
Sbjct: 1385 ELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSS 1444

Query: 3520 PLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQE 3579
            P    G   P   S HS+      +KD PR  +  R E     +   +            
Sbjct: 1445 PGLRDGSGTP---SRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPS 1501

Query: 3580 ETDWFDK---PRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGP 3636
              +  +K   P+  RS          V+ +   +     S  + D  P        E   
Sbjct: 1502 SPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDS 1561

Query: 3637 GRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQ 3696
               + AK          SG     +   R +   +R     E +   +P +AP    + Q
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVK--DKPRAAP----RAQ 1615

Query: 3697 PGYPSSAEYSQPS-RASSAYHHASDSKKGSRQAHSGPAALQSKAE--PQAQPQLQGRQAA 3753
             G  SS E   P+ RA      +  S KG   +  G ++ +S  E  P+++   +G +++
Sbjct: 1616 SGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS 1675

Query: 3754 PGPQ-QSQSP----SSRQIP-----------SGAASRQPQTQQQQQGL--------GLQP 3789
            P P+ +S++P    SSR  P           S +AS  P+T+ +              +P
Sbjct: 1676 PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEP 1735

Query: 3790 PQQALTQARLQQQSQPTTRGSAPAASQPAGKP---QPGPSTATGPQPAGPPRAEQTNGSK 3846
             +++ +  R +  S P T+ ++     P+ KP   Q   S +   +     R +++  S+
Sbjct: 1736 AEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQ 1795

Query: 3847 GTAKAPQQGRA 3857
             T++  Q+ R+
Sbjct: 1796 STSRRRQRSRS 1806



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 78/340 (22%), Positives = 122/340 (35%), Gaps = 47/340 (13%)

Query: 16   LPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGP-GPGPGP- 73
            L P  +  G  P         P A +G    P   A    A+P     G    G GP P 
Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPE 1650

Query: 74   GSTSRRLDPKEPLGNQRA-----ASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRT 128
            GS+S    P+ P  ++ A     +SP PK  S T P   S R +            P  T
Sbjct: 1651 GSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS------------PELT 1698

Query: 129  LQVDSRTQRSGRSPSVSPD-RGSTPTSPYSVPQIA-PLPSSTLCPICKTSDLTSTPSQPN 186
             +  +R  R  RS S SP+ R  TP      P ++ P P+       ++S    + S P 
Sbjct: 1699 RK--ARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEK----SRSSRRRRSASSPR 1752

Query: 187  FNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPA 246
              T ++           +P P   Q         + +     D + + +S S+++  S +
Sbjct: 1753 TKTTSRRGRSP------SPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRS 1806

Query: 247  LSP------------AHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVP--GPAQ 292
             S             + SPA+Q   +    R RG     P SR+   +R +  P      
Sbjct: 1807 RSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRS 1866

Query: 293  AAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAV 332
             A+P    R   + P  ++  +     P     ++S T+V
Sbjct: 1867 RASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSV 1906



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 259/1315 (19%), Positives = 401/1315 (30%), Gaps = 167/1315 (12%)

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKT 432
            T    A S  T +     A+ +     L +G  P PA G       R G G  P + P T
Sbjct: 264  TSADSASSSDTSRSRSRSAAAKTHTTAL-AGRSPSPASG-------RRGEGDAPFSEPGT 315

Query: 433  GGTTSPKHGR-AEHQAASKAAAKPKTMPKERAICPLCQAELN-VGSKSPANYNTCTTCRL 490
              T  P     A  Q +S    K K   ++ A  P    E +  G + PA          
Sbjct: 316  TSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPA---------- 365

Query: 491  QVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT 550
                     PTP L E+                  G P PL      Q PV  P  A   
Sbjct: 366  ---------PTPLLAERHG----------------GSPQPLATTPLSQEPVNPPSEA--- 397

Query: 551  SPLKQKGPQGLGQPSGP--LPAKASPLSTKASPLPSKASPQAKPLRAS-EPSKTPSSVQE 607
            SP + + P     P  P  LP  +S  S+  SP P+K S  A     S +P+  P S +E
Sbjct: 398  SPTRDRSP-----PKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHRE 452

Query: 608  KKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGK 667
              +   +K     +   + + +  TP  + G  R+          P   K G +      
Sbjct: 453  ISSSPTSKNRSHGRAKRDKSHS-HTPSRRMGRSRS----------PATAKRGRSRSRTPT 501

Query: 668  PYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKV 727
                  SRSPQ          G S S                      P  P  S     
Sbjct: 502  KRGHSRSRSPQWRRSRSAQRWGRSRSPQR-------------RGRSRSPQRPGWSRSRNT 548

Query: 728  GSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDS 787
                R     +G + S               +R  S S TP    S             +
Sbjct: 549  QRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRT 608

Query: 788  AEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQI 847
               R R   +  A       S +R            S  P +   R+   T     R + 
Sbjct: 609  PARRGRSRSRTPARRRSRTRSPVR--------RRSRSRSPARRSGRSRSRTPARRGRSRS 660

Query: 848  LEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRP--EPSQEPAALPKRRLPHNATTGY 905
               +    +        SGR  ++   ++G  R R          +L +R   H+ T   
Sbjct: 661  RTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTP-- 718

Query: 906  EELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEME 965
            +     G S+E  + S T Q   R   + E+  +            P         L   
Sbjct: 719  QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLR-R 777

Query: 966  SLTGS---PEDRSR-GEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQ 1021
            SL+GS   P+ +S+     S   +S P   S T P         S SSP  +Q+ +   +
Sbjct: 778  SLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR-----RSRSSSSPPPKQKSKTPSR 832

Query: 1022 QRKARHRSHGPL---LPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDK 1078
            Q  +    H  +    P  + S    +  E+    + +          ++S   +T    
Sbjct: 833  QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKS---RTPSRH 889

Query: 1079 EELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPS-------PS 1131
                +   R +S TPP   SP   +SP  +++      +   S  S  SPS       P 
Sbjct: 890  SCSGSSPPRVKSSTPPRQ-SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPR 948

Query: 1132 LDSEAEALDGGPSRL---YKSGSEYNLPTFMSLYSPTETPSGSSTTP--------SSGRP 1180
                        SRL   Y      +  T +   +P       S +P          G  
Sbjct: 949  RSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPS 1008

Query: 1181 LKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEY--QDTTDREYG 1238
            L  ++    +   K  L+Q   G  +   G            G+ S +   Q  T  ++ 
Sbjct: 1009 LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH- 1067

Query: 1239 QAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASS-RDLAFAEDKKKEKQFLNAESAY 1297
            ++   + E   +   +   +   QTS    R R +S   +LA     ++++   +A    
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127

Query: 1298 MDPMK------QNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQ 1351
               M       Q+     P      L       T  S +        D   +    K+  
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKF 1187

Query: 1352 DPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPS 1411
             P  +   P S       +  P  +  G  ++       + LP            E+S  
Sbjct: 1188 SPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEE 1247

Query: 1412 PSSTAHSYGHSP----TTANYGS--QTEDLPQAPSGL----AAAGRAAREKPLSASDGEG 1461
            P+    S+  S     +T+N+ S  + E+ P     L    + A   A E P  AS   G
Sbjct: 1248 PAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGG 1307

Query: 1462 GTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSP 1521
                P        S+SP    S  S     + G +G      FS++         + +  
Sbjct: 1308 PHFSPEHKE---LSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLE 1364

Query: 1522 GAPTPSPMVAQGTQTPHR------PSTPRLVWQESSQEAPFMVITLASDASSQTRMVHAS 1575
              P+   M  Q T++         P         S+Q     V+       S+ R   +S
Sbjct: 1365 TDPS-LDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRER--SSS 1421

Query: 1576 ASTSPLCSPTETQPTTHGYSQTTP--------PSVSQLPPEPPGPPGFPRVPSAG 1622
            AS+  +       P+    S ++P        PS   L    PG    PR PS G
Sbjct: 1422 ASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRG 1476



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 65/280 (23%), Positives = 103/280 (36%), Gaps = 28/280 (10%)

Query: 2600 RRRRARRSADCSVQTDDEDSA-------EWEQPVRRRRSRLPRHSDSGSDSKHDATASSS 2652
            ++ R RRS   S + + + S+       E E   R+ RS  P+      D K   + S++
Sbjct: 193  KKDRGRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTT 252

Query: 2653 SAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGR 2712
             A  + RA  S    + S  S  T   +    +   H TA             +P    R
Sbjct: 253  PAPKSRRAHRSTSADSAS--SSDTSRSRSRSAAAKTHTTALAGRS-------PSPASGRR 303

Query: 2713 GESLACQTEPDGQA-QGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKK--KPDPLEIG 2769
            GE  A  +EP   + Q  + P+       SPY             + EK   +P P    
Sbjct: 304  GEGDAPFSEPGTTSTQRPSSPETATKQPSSPY-------EDKDKDKKEKSATRPSPSPER 356

Query: 2770 YQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFT 2829
                  P + + L++ +   SPQ L +  +PLS   +   S AS  R      SP+K   
Sbjct: 357  SSTGPEPPAPTPLLAERHGGSPQPLAT--TPLSQEPVNPPSEASPTRDRSPPKSPEKLPQ 414

Query: 2830 ADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFS 2869
            + S+      P+P K  + + S P+   P     +    S
Sbjct: 415  SSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREIS 454



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 50/196 (25%), Positives = 75/196 (38%), Gaps = 24/196 (12%)

Query: 3685 PSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQ 3744
            P++  A+   G    P++A Y   SR   A   AS +  G R AH+            A 
Sbjct: 2303 PAALAALSLTGSGTPPTAANYPSSSRTPQA--PASANLVGPRSAHA-----------TAP 2349

Query: 3745 PQLQGRQAAPGPQQSQSPSSRQIP--SGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQ 3802
              + G + A     +   S+R  P  SGA    P+       L         T   L  +
Sbjct: 2350 VNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP-----LSAYERVSGRTSPPLLDR 2404

Query: 3803 SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---PPRAEQTNGSKGTAKAPQQGRAPQ 3859
            ++  T  SAP+ S+   +  P PS+  G  P+    PP  +Q      +A +  Q R   
Sbjct: 2405 ARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFS-DQSRCLI 2463

Query: 3860 AQPAPGPGPAGVKAGA 3875
            AQ  P  G   + +GA
Sbjct: 2464 AQTTPVAGSQSLSSGA 2479



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 57/230 (24%), Positives = 83/230 (36%), Gaps = 45/230 (19%)

Query: 1402 SPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEG 1461
            +PA   R    S++A S   S T+    S++          A AGR+    P S   GEG
Sbjct: 252  TPAPKSRRAHRSTSADSASSSDTSR---SRSRSAAAKTHTTALAGRSP--SPASGRRGEG 306

Query: 1462 GTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSP 1521
              P      +   S+  P SP + ++ P+ SP +   +   E S   PSP+P       P
Sbjct: 307  DAPFSEPGTT---STQRPSSPETATKQPS-SPYEDKDKDKKEKSATRPSPSPERSST-GP 361

Query: 1522 GAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPL 1581
              P P+P++A+     H  S   L     SQE                          P+
Sbjct: 362  EPPAPTPLLAER----HGGSPQPLATTPLSQE--------------------------PV 391

Query: 1582 CSPTETQPTTHGYSQTTP-----PSVSQLPPEPPGPPGFPRVPSAGADGP 1626
              P+E  PT       +P      S S+  P  P P    R  S+  + P
Sbjct: 392  NPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESP 441



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 200/980 (20%), Positives = 317/980 (32%), Gaps = 152/980 (15%)

Query: 2344 GGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQR 2403
            GGSG  SR    +E +    R+R+ + +     R+R    + R      +  R R     
Sbjct: 1816 GGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKR---SRSRTSPAPWKRSRSRASPAT 1872

Query: 2404 HREEEQL--LVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQ 2461
            HR       L+ R     +T     + +++   +     +R +     +     ++  + 
Sbjct: 1873 HRRSRSRTPLISRRRSRSRTSP---VSRRRSRSRTSVTRRRSRSRASPVS----RRRSRS 1925

Query: 2462 LQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIAMAGPEGLGQ 2521
                +  ++ R + P      +  R PP+      ++    PP+T     +   P    +
Sbjct: 1926 RTPPVTRRRSRSRTPTTRR-RSRSRTPPVTRR---RSRSRTPPVTRRRSRSRTSPITRRR 1981

Query: 2522 PRE---PVLHRGLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVR 2578
             R    PV  R    S S  S  T  +  +  S + +R S  R          T P + R
Sbjct: 1982 SRSRTSPVTRR---RSRSRTSPVTRRRSRSRTSPVTRRRSRSR----------TPPAIRR 2028

Query: 2579 RIADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSD 2638
            R    +     +   SR  L+ RRR+R     + +   + S     P  RRRS     SD
Sbjct: 2029 RSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTAR--GKRSLTRSPPAIRRRSASGSSSD 2086

Query: 2639 SGSDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKV 2698
                +   AT + S +     A++S  +   S  S+   P    R    +    ++   +
Sbjct: 2087 RSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPM 2146

Query: 2699 EIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRF 2758
             +++        G G  +     PD Q   V  P+    + I+  L  I + T  P    
Sbjct: 2147 SVLQQAGGSMMDGPGPRI-----PDHQRTSV--PENHAQSRIALALTAISLGTARP---- 2195

Query: 2759 EKKKPDPLEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLN 2818
                            PP   +  ++ +  + P    +PV PL   R             
Sbjct: 2196 ----------------PPSMSAAGLAARMSQVP----APV-PLMSLR------------- 2221

Query: 2819 KAHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLG 2878
                      TA +A     +P          S   P  PTA   A  R         L 
Sbjct: 2222 ----------TAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLA 2271

Query: 2879 SQVSALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKA 2938
            S  +A+ P+++     RT  +P      + LAG  +P   AA  L    T PT      +
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPA-----VNLAGARTPAALAALSLTGSGTPPTAANYPSS 2326

Query: 2939 SLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRD 2998
            S   +      LV   S       A ++       A L    L               R 
Sbjct: 2327 SRTPQAPASANLVGPRSAHAT---APVNIAGSRTAAALAPASL------------TSARM 2371

Query: 2999 YPPLRG--LGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRF 3056
             P L G  L   R  LS  E    R+ G T+P    +D    A +   PS P+  +    
Sbjct: 2372 APALSGANLTSPRVPLSAYE----RVSGRTSPP--LLD---RARSRTPPSAPSQSRMTSE 2422

Query: 3057 QPPAPQYSAGSGGPTQNGFP-AHQAPTYPGPSTYP-------APAFPPGASYPAEPGLPN 3108
            + P+P    G   P+Q+  P A   P  P PS +        A   P   S     G   
Sbjct: 2423 RAPSPSSRMGQA-PSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSG--- 2478

Query: 3109 QQAFRPTGHYAG------QTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYE 3162
              A   T   AG        P P    +    P  S    Q     +L   +++  ++  
Sbjct: 2479 --AVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSS 2536

Query: 3163 VIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAP---------- 3212
              +S     SS+ S +S S  + SS  E   +P  P    +   S +PAP          
Sbjct: 2537 SSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPP 2596

Query: 3213 -TYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGE 3271
               P+     S   +   +       S  +  S+S++  S         SS     +PG 
Sbjct: 2597 EPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG- 2655

Query: 3272 PGVLDGPTLPCCYARGEEES 3291
            P  L  P  P     GE  S
Sbjct: 2656 PQALPKPASPKKPPPGERRS 2675



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 205/1038 (19%), Positives = 319/1038 (30%), Gaps = 181/1038 (17%)

Query: 2882 SALPPNSLVRKVKRTLPSPPPEEAHLPLAGQASPQLYAASLLQRGLTGPTTVPATKASLL 2941
            S+  P    R+ K+  P PP                   SL++   +  +  P  K    
Sbjct: 149  SSFDPQRRAREAKQPAPEPPKPY----------------SLVRESSSSRSPTPKQKKKKK 192

Query: 2942 RELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKD----RGGR 2997
            ++ DR  R       + RKK ++  +   E ++K K      T + +  +KD    R   
Sbjct: 193  KK-DRGRRSESSSPRRERKKSSKKKKHRSESESK-KRKHRSPTPKSKRKSKDKKRKRSRS 250

Query: 2998 DYPPLRGLGEHR----DYLSDSELNQLRLQGC-----TTPAGQFVDFPATAA-----APA 3043
              P  +    HR    D  S S+ ++ R +       TT        PA+       AP 
Sbjct: 251  TTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPF 310

Query: 3044 TPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAE 3103
            +  G T+ Q+P   P        S    ++     ++ T P PS       P  +S   E
Sbjct: 311  SEPGTTSTQRPS-SPETATKQPSSPYEDKDKDKKEKSATRPSPS-------PERSSTGPE 362

Query: 3104 PGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEV 3163
            P  P            G +P P   + L   P +  +     R  S     +K+P +   
Sbjct: 363  PPAPTPLL----AERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSS 418

Query: 3164 IASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSL 3223
             +SP  P  +  S  + S P      E  K    P  G    +S S  PT  + SH    
Sbjct: 419  ESSPPSPQPTKVSRHASSSP------ESPK--PAPAPGSHREISSS--PTSKNRSH---- 464

Query: 3224 EQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCC 3283
                              +D + +   S+R+      ++ + G+          PT    
Sbjct: 465  --------------GRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRT-----PT---- 501

Query: 3284 YARGEEESEEDSY---DPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMG 3340
              RG   S    +       + G  RS +  GR  S    G S  R+  R  +      G
Sbjct: 502  -KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRG 560

Query: 3341 PKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSR 3400
              H   S +PA  +  RS+ R      +    +P            S  P    S   + 
Sbjct: 561  RSH---SRSPA--TRGRSRSRTPARRGRSRSRTPARRRS------RSRTPTRRRSRSRTP 609

Query: 3401 GRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFS 3460
             R+ +       ++    +     +  R          G SRSR P+             
Sbjct: 610  ARRGRSRSRTPARRRSRTRSP---VRRRSRSRSPARRSGRSRSRTPAR------------ 654

Query: 3461 GWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGP 3520
               +G  R R    R +     P+  S   SR R P R   S   +P     R R     
Sbjct: 655  ---RGRSRSRTPARRGRSRSRTPARRS-GRSRSRTPARRGRSRSRTPRRGRSRSR----- 705

Query: 3521 LPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEE 3580
                  +  +   SHS    Q   + G  +    +              + +   +    
Sbjct: 706  ------SLVRRGRSHSRTP-QRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRR 758

Query: 3581 TDWFDKPRDARSDRF---RHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWP-----HD 3632
            +     PR     R    R   G +     + + P R S     +P  +   P       
Sbjct: 759  SRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSS 818

Query: 3633 EGGPGRHASAKEHR--HGDHGRHSGRHTGEEPGRRA-AKPHARDLGRHEARPHSQPSSAP 3689
               P +  S    R  H     H    +G  P + +   P A +      R     SS  
Sbjct: 819  SSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPD 878

Query: 3690 AMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQG 3749
               K   P   S +  S P   SS     S S+  S Q             P+ +  +  
Sbjct: 879  PELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQ-------------PKVKAIISP 925

Query: 3750 RQAAPGPQQSQSPS---SRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPT 3806
            RQ +     S SPS   SR  P  + S  P +                 ++RL  +   +
Sbjct: 926  RQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSN---------------VESRLLPRYSHS 970

Query: 3807 TRGSAPAASQPAGKPQPGPSTATGPQP---AGPPRAEQTNGSKGTAKAPQQ-GRAPQAQP 3862
               S     +P   P+   S +  P P   A  P     +GSK  +  PQ+  +    Q 
Sbjct: 971  GSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSK--SPCPQEKSKDSLVQS 1028

Query: 3863 APGPGP--AGVKAGARPG 3878
             PG     AGVK+   PG
Sbjct: 1029 CPGSLSLCAGVKSSTPPG 1046



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 36/144 (25%), Positives = 55/144 (38%), Gaps = 10/144 (6%)

Query: 3683 SQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQ 3742
            S  SS+ +          SS+  S  S +SS+   +S S      A  GP AL   A P+
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666

Query: 3743 AQPQLQGRQAAPGPQQSQSPSSRQIP-SGAASRQPQTQQQQQGLGLQPPQQALTQARLQQ 3801
              P  + R  +P         SR +  S    R+P  Q   +       QQ+ +  R  +
Sbjct: 2667 KPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPR------DQQSSSSERGSR 2720

Query: 3802 QSQPTTRGSAPAASQPAGKPQPGP 3825
            + Q   RG + + S    +  P P
Sbjct: 2721 RGQ---RGDSRSPSHKRRRETPSP 2741



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 135/635 (21%), Positives = 203/635 (31%), Gaps = 90/635 (14%)

Query: 960  PELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEA 1019
            P +   S +GS  DRSR   S+T PA+     S T P +L+S      S PS      + 
Sbjct: 2073 PAIRRRSASGSSSDRSR---SATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLD- 2128

Query: 1020 KQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
                  R RS G L P     +    L++    + +    R  + QR        +    
Sbjct: 2129 ------RCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIA 2182

Query: 1080 ELRAQRRRERSKTPPS--------NLSPIEDASPTEELRQAAEMEELHR----SSCSEYS 1127
                      ++ PPS         +S +    P   LR A       R    S+ +   
Sbjct: 2183 LALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNL 2242

Query: 1128 PSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEA 1187
             S    +   A++   SR   + +  NL +  +  +P+        TP++  P  +   A
Sbjct: 2243 ASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTA--PAVNLAGA 2300

Query: 1188 YEEMMRKAELLQRQQGQAAGARGPHGG--PSQPTGPRGLGSFEYQDTTDREYGQAAQPAA 1245
                   A  L         A  P     P  P     +G      T        ++ AA
Sbjct: 2301 RTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIA-GSRTAA 2359

Query: 1246 EGTPASLGAAVYEEILQTSQ------SIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMD 1299
               PASL +A     L  +        +    + S R      D+ + +   +A S    
Sbjct: 2360 ALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRM 2419

Query: 1300 PMKQNGGPLTP-GTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
              ++   P +  G +P+Q   P +   P S   S         + Q         L   +
Sbjct: 2420 TSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA 2479

Query: 1359 SPASPSSASKEIGMPFSQGPGTP---------ATTAVAPC------PAGLPRGYMTPASP 1403
               + SSA    GM     PG P         +T A  P       PA   R   + +S 
Sbjct: 2480 VATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSS 2539

Query: 1404 AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQA-----PSGLAAAGRAARE------- 1451
            + S  S S SS++ S   S ++ + GS     P+      PS   A   A RE       
Sbjct: 2540 SSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT 2599

Query: 1452 -------------------KPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFS 1492
                                  S+S     +   S + S  +SSS   SP         S
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP---------S 2650

Query: 1493 PGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPS 1527
            P K GP+A  +       P P     RSP  P  S
Sbjct: 2651 PAKPGPQALPK-PASPKKPPPGERRSRSPRKPIDS 2684



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 49/262 (18%), Positives = 89/262 (33%), Gaps = 41/262 (15%)

Query: 3666 AAKPHARDLGRHEARPHSQPSSAPAM----PKKGQPGYPSSAEYSQPSR----------- 3710
            +A   +R        P S+   AP+     P + QP  P  + +S  SR           
Sbjct: 2412 SAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAG 2471

Query: 3711 -------------ASSAYHHASDSKKGSRQAHSG---PAALQSKAEPQA----QPQLQGR 3750
                         +S+  H+   S       HS    P A     +P A    QP  + R
Sbjct: 2472 SQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERR 2531

Query: 3751 QAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQS---QPTT 3807
             ++     S S SS    S ++S    +    +G  L P Q  +   R+   +   +   
Sbjct: 2532 SSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSL-PVQPEVALKRVPSPTPAPKEAV 2590

Query: 3808 RGSAPAASQPAGKPQ--PGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPG 3865
            R   P    PA + +     S+++    +    +  ++ S  ++ +     +  +  +P 
Sbjct: 2591 REGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPS 2650

Query: 3866 PGPAGVKAGARPGGTPGAPAGQ 3887
            P   G +A  +P      P G+
Sbjct: 2651 PAKPGPQALPKPASPKKPPPGE 2672



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 91/458 (19%), Positives = 141/458 (30%), Gaps = 38/458 (8%)

Query: 2236 VPLTSLTRVPM--IAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGA 2293
            VPL SL   P   +A R+P          A +R P   ++P A        PAAA A   
Sbjct: 2215 VPLMSLRTAPAANLASRIPAASAAAMNL-ASARTP---AIPTAVNLADSRTPAAAAAMNL 2270

Query: 2294 GGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQK------PPADAAPGGGSG 2347
              P     P      +P   T PA     AGA  PA LA         PP  A     S 
Sbjct: 2271 ASPRTAVAPSAVNLADPRTPTAPAV--NLAGARTPAALAALSLTGSGTPPTAANYPSSSR 2328

Query: 2348 ALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREE 2407
                P        +                  +    L   R+   L    +   R    
Sbjct: 2329 TPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPR---- 2384

Query: 2408 EQLLVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLE 2467
               +     + +       L  +   R    A  + ++  +R      +  Q   Q  L 
Sbjct: 2385 ---VPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLP 2441

Query: 2468 EQKQRQKAPFPAACEAPGR-----GPPLAAAELAQNGQYWPPLTHAAFIAMAGPEG--LG 2520
              + + ++P P+A     R       P+A ++   +G        A   + AG     L 
Sbjct: 2442 PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAV------ATTTSSAGDHNGMLS 2495

Query: 2521 QPREPVLHRGLPSSASDMSLQTEEQWEASRSGIKKRHSMPRLRDACELESGTEPCVVRRI 2580
             P   V H  +    +    Q      A +   ++R S      +    S +        
Sbjct: 2496 VPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSS----SSS 2551

Query: 2581 ADSSVQTDDEDGESRYLLSRRRRARRSADCSVQTDDEDSAEWEQPVRRRRSRLPRHSDSG 2640
            + SS  +   D E   L  +   A +          E   E   P      R  R S S 
Sbjct: 2552 SSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSS 2611

Query: 2641 SDSKHDATASSSSAAATVRAMSSVGIQTISDCSVQTEP 2678
            S S   +++SSSS++++  + SS    + S  S  + P
Sbjct: 2612 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSP 2649



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 51/230 (22%), Positives = 86/230 (37%), Gaps = 18/230 (7%)

Query: 2624 QPVRRRRSRLPRHSDSGSDSKHDATASSSSAAATVRAMS-SVGIQTISDCSVQTEPDQLP 2682
            QP + RRS     S S S S   +++SSSS++ +  + S    +    + +++  P   P
Sbjct: 2525 QPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTP 2584

Query: 2683 RVSPAIHITAATDP-------KVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAGPQLV 2735
                A+      +P       +       S+   +    S +  +     +   +     
Sbjct: 2585 APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644

Query: 2736 GPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLPPESLSQL-VSRQPPKSPQVL 2794
              ++ SP  PG Q + P P      KKP P E   ++  P + +  L  SR    SP   
Sbjct: 2645 SSSSPSPAKPGPQAL-PKPA---SPKKPPPGE--RRSRSPRKPIDSLRDSRSLSYSPVER 2698

Query: 2795 YSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPMK 2844
              P    SP    D   +SSER ++          +    R+   PRPM+
Sbjct: 2699 RRPSPQPSPR---DQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMR 2745



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 42/182 (23%), Positives = 62/182 (34%), Gaps = 37/182 (20%)

Query: 1447 RAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFST 1506
            R +++K    S      P+  RA+   ++ S   S +S S S      +     T   + 
Sbjct: 238  RKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRS------RSAAAKTHTTAL 291

Query: 1507 QTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDAS 1566
               SP+PAS       AP   P    GT +  RPS+P    ++ S           S   
Sbjct: 292  AGRSPSPASGRRGEGDAPFSEP----GTTSTQRPSSPETATKQPS-----------SPYE 336

Query: 1567 SQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGP 1626
             + +     ++T P  SP                  S   PEPP P         G+  P
Sbjct: 337  DKDKDKKEKSATRPSPSPER----------------SSTGPEPPAPTPLLAERHGGSPQP 380

Query: 1627 LA 1628
            LA
Sbjct: 381  LA 382


>gi|239754327 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 85.5 bits (210), Expect = 9e-16
 Identities = 183/787 (23%), Positives = 275/787 (34%), Gaps = 112/787 (14%)

Query: 14  GPLPPGGAG-----PGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVP---GPGP 65
           G L PG  G     P P PGP PG  +  S P GG  LP   +  STA PP P    P P
Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLP---SPPSTAPPPPPLLLEPPP 182

Query: 66  GPGPGPGPGSTSRRLDPKEPLGNQR----------------AASPTPKQASATTPGHESP 109
            P   P P      L P   L +                   A P P   +   P   SP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 110 RE--TRAQGPAG---QEADGPRRTLQVDSRTQRSGRSPSVSPDR--GSTPTSPYSVPQIA 162
               TR   P G    ++D      Q ++      RSP+       G  P    + P+  
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSF 302

Query: 163 PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222
            +P  T  P+ +TS +    +Q           K  ++    P+ H+    +        
Sbjct: 303 KVPPPT--PV-RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE 359

Query: 223 QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282
               G    TAP S    Q  S A   A +P   P   P       P  P P        
Sbjct: 360 PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPP-------PAPPLPPPAPPLPP 412

Query: 283 RATSVPGPAQAAAPPEVGRVSPQPPQPT-KPSTAEPRPPAGEAPAKSATAVPAGLGATEQ 341
            A  +P   +AA PP     +P+   P  KP   +P PP+ E  A SA          E+
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKP---KPNPPSPENTASSAPVDWRDPSQMEK 469

Query: 342 TQEGLTGKLFGLGAS---LLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
            +  L   L G       L  +    ++ Q +   +G   P K T   + +  +K+  P 
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET---LLSLPAKDTPPG 526

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
                 G       +  P   +        +P+   T S +  R E +A   +AA+ +  
Sbjct: 527 VPEKSLGGSSLTETEAAPSLTL---PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK 583

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
           P             ++GS  P         RL+   +C        + K     L  Q+ 
Sbjct: 584 P-------------SIGSLPPKP-------RLEGGRICENGADDDKLSKPVAKNLPPQST 623

Query: 519 RLLEGSLGEP-----TPLPPPTSQQPPVGAPHRAS---GTSPLKQKGP----QGLGQPSG 566
            LL  +  +P       +PP  + +P +  P +A+    T P    GP    +    P+ 
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKATSGPTT 681

Query: 567 PLPAKASP-LSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE 625
           PL A + P +++ A+ LP+  S Q    + S P+  P     ++   P++A        E
Sbjct: 682 PLKATSGPAIASTATTLPTTTS-QLMAEKDSGPAGQPEKPASQEVSTPSQAR------GE 734

Query: 626 TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ------S 679
            +P+ AT     G R +    P       +P GGE   L  KP+   +S S +      +
Sbjct: 735 GSPSEATRLPTQGARSSAAFPP-----KTSPGGGEVPCLY-KPHCHQSSLSREVAVVMPT 788

Query: 680 LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQG 739
           L+  G +  G      E  G+  +             HP +  E+ + GS M  LL A+ 
Sbjct: 789 LARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT-GEVVERGSPMALLLAARQ 847

Query: 740 LAPSERS 746
            A   RS
Sbjct: 848 RAQKGRS 854



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 85/340 (25%), Positives = 124/340 (36%), Gaps = 53/340 (15%)

Query: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418
            +P  P   S+  G     G   P+  + AP P  L    + P  P      P P   A S
Sbjct: 147  APGPPQDISEPPG-----GSPLPSPPSTAPPPPPL---LLEPPPPPSMAPPPPPVLEALS 198

Query: 1419 YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP 1478
              H+ ++ +  +  + +P AP     A  A    P+ A       P P+  ++      P
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPP---LAFLAPPPPPVPAP----APPAPASPHTVGTRLFP 251

Query: 1479 PLSPSS----------PSESPTFSPGKMGPRATAE--FSTQTPSPAPASDMPRSPGAPTP 1526
            P   +            +E+   SP    PR+ AE   S   P+P P    PRS   P P
Sbjct: 252  PGGVTKWKSDVALNGRQAEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307

Query: 1527 SPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTE 1586
            +P+             PR   + ++++AP  +    S        V+   +  P C P E
Sbjct: 308  TPVRTSSIPVQEAQEAPRKE-EGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC-PGE 365

Query: 1587 TQPTTH-----GYSQ--------TTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWG 1633
             + T       G SQ        T PP+    PP PP PP  P +P A    PL      
Sbjct: 366  LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--PLPCAQKA 423

Query: 1634 ALPAENISLCRISSVPGTSRVEPGPRTP----GTAVVDLR 1669
            A P    +    SS P   + +P P +P     +A VD R
Sbjct: 424  AHPPAGFTKTPKSSSPAL-KPKPNPPSPENTASSAPVDWR 462



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 71/334 (21%), Positives = 116/334 (34%), Gaps = 40/334 (11%)

Query: 1308 LTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSAS 1367
            L P   P    AP +   P S  + G R+ P   VT+  +    +  +  ++ ASP  + 
Sbjct: 224  LAPPPPPVPAPAPPA---PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280

Query: 1368 KE---------------IGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGS-ERSPS 1411
             E                   F   P TP  T+  P    +      P    G+ +++PS
Sbjct: 281  AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP----VQEAQEAPRKEEGATKKAPS 336

Query: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAARE--KPLSASDGEGGTPQPSRA 1469
                  S+   P +  Y  +  + P  P  L A   A+    +  S +D   GTP P+  
Sbjct: 337  RLPLPPSFHIRPASQVYPDRAPE-PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                A   PP +P  P  +P     +      A F+    S +PA  +   P  P+P   
Sbjct: 396  LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA--LKPKPNPPSPE-- 451

Query: 1530 VAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQP 1589
                    +  S+  + W++ SQ         A    S+      S    P  +P +++ 
Sbjct: 452  --------NTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP-QSKE 502

Query: 1590 TTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGA 1623
               G       ++  LP +   PPG P     G+
Sbjct: 503  GKKGPRLPEKETLLSLPAKDT-PPGVPEKSLGGS 535



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 54/207 (26%), Positives = 71/207 (34%), Gaps = 37/207 (17%)

Query: 3042 PATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPG---- 3097
            P T S P+    P F PPAP  +  +  P     PA  AP    P T     FPPG    
Sbjct: 200  PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTK 257

Query: 3098 ----------------ASYPAEPGLPNQQAFRP------TGHYAGQTPMPT-TQSTLFPV 3134
                            AS P  P  P   A  P      T   + + P PT  +++  PV
Sbjct: 258  WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317

Query: 3135 PADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV-----PMSSAPSETSYSGPAVSS-G 3188
                 AP ++   T  A     +P ++ +  +  V     P    P E   + PA    G
Sbjct: 318  QEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLG 377

Query: 3189 YEQGKVPEVPRAGDRGSVSQSPAPTYP 3215
              Q +  E  RAG        P P  P
Sbjct: 378  QSQSQADE--RAGTPPPAPPLPPPAPP 402



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 42/175 (24%), Positives = 63/175 (36%), Gaps = 13/175 (7%)

Query: 2198 INTPIAATLP---ITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLG 2254
            ++ P+A  LP    T  P + L+P    G   P  +    A+P    T  P   P+  LG
Sbjct: 610  LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP-PKATLWPATPPKATLG 668

Query: 2255 PTGLYRYPAPSRFPIASSVPPAEG------PVYLGKPAAAKAPGAGGPSRPEMPVGAARE 2308
            P    +  +    P+ ++  PA        P    +  A K  G  G  +PE P      
Sbjct: 669  PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG--QPEKPASQEVS 726

Query: 2309 EPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGS-GALSRPGFEKEEASQE 2362
             P       +  EA   P     +    P   +PGGG    L +P   +   S+E
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 90/389 (23%), Positives = 127/389 (32%), Gaps = 73/389 (18%)

Query: 1294 ESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
            + A   P K+ G       +P++L  P SF    +S     +V PD       A E   P
Sbjct: 318  QEAQEAPRKEEGATKK---APSRLPLPPSFHIRPAS-----QVYPDR------APEPDCP 363

Query: 1354 LKLHSS-PASP------SSASKEIG-------MPFSQGPGTPATTAVAPCPAGLPRGYMT 1399
             +L ++ PASP      S A +  G       +P    P  P    + P    LP     
Sbjct: 364  GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKA 423

Query: 1400 PASPAGSERSPSPSSTAHSYGHSPTT-------------------------ANY--GSQT 1432
               PAG  ++P  SS A     +P +                         A Y  GS+ 
Sbjct: 424  AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483

Query: 1433 ED-----------LPQAPSGLAAAGRAAREKPLS--ASDGEGGTPQPSRAYSYFASS--S 1477
            ED            PQ+  G        +E  LS  A D   G P+ S   S    +  +
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 1478 PPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTP 1537
            P L+  S    P  SP     +   E   +  S A     P S G+  P P +  G    
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICE 602

Query: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQT 1597
            +     +L  +  ++  P    TL    S Q + +   A   P  +P    P        
Sbjct: 603  NGADDDKLS-KPVAKNLPPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKATLWPA 660

Query: 1598 TPPSVSQLPPEPPGPPGFPRVPSAGADGP 1626
            TPP  +  P  P      P  P     GP
Sbjct: 661  TPPKATLGPATPLKATSGPTTPLKATSGP 689



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 59/248 (23%), Positives = 81/248 (32%), Gaps = 48/248 (19%)

Query: 2713 GESLACQTEPDGQAQGV--------AGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD 2764
            G+ L     P G A G          G  L  P + +P  P + +  P P        P 
Sbjct: 134  GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP----PSMAPP 189

Query: 2765 PLEIGYQAHLPPESLSQ---------------LVSRQPPKSPQVLYSPVSPLSPH----R 2805
            P  +  +A  PP +LS                L    PP  P    +P +P SPH    R
Sbjct: 190  PPPV-LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 2806 LLD----TSFASSERLN-----KAHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPL 2856
            L      T + S   LN         SP +             P P  T  RS   P P 
Sbjct: 249  LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308

Query: 2857 S-PTAEESAKERFSLYQHQGGLGSQVSA---LPPNSLVRKVKRTLPSPPPE---EAHLPL 2909
               T+    +E     + + G   +  +   LPP+  +R   +  P   PE      L  
Sbjct: 309  PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368

Query: 2910 AGQASPQL 2917
               ASP+L
Sbjct: 369  TAPASPRL 376



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 52/196 (26%), Positives = 74/196 (37%), Gaps = 27/196 (13%)

Query: 3028 PAGQFVDFPATAAAPATPSG--PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            PA Q   +P  A  P  P     TA   PR      Q    +G P     PA   P    
Sbjct: 348  PASQV--YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP----PAPPLPPPAP 401

Query: 3086 PSTYPAPAFPPGASYPAEPGLP-NQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQK 3144
            P   PAP  PP A     P LP  Q+A  P    AG T  P + S   P       P   
Sbjct: 402  PLPPPAPPLPPAA-----PPLPCAQKAAHPP---AGFTKTPKSSS---PALKPKPNPPSP 450

Query: 3145 PRQTSLADLEQKVPTNYEVIASPVVP-MSSAPSETSY----SGPAVSSGYEQGKVPEVPR 3199
                S A ++ + P+  E + + +   +  +  E  +     GP V+   ++GK  + PR
Sbjct: 451  ENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK--KGPR 508

Query: 3200 AGDRGSVSQSPAPTYP 3215
              ++ ++   PA   P
Sbjct: 509  LPEKETLLSLPAKDTP 524



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 36/132 (27%), Positives = 45/132 (34%), Gaps = 11/132 (8%)

Query: 3780 QQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---- 3835
            Q  Q L + PP         Q  S+P   G +P  S P+  P P P     P P      
Sbjct: 132  QYGQDLLIPPPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 3836 PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA-GQPGADGES 3894
            PP   +      T  +P     P   P P P  A +     P   P  PA   P   G  
Sbjct: 190  PPPVLEALSPPHTLSSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 3895 VFSKILPGGAAE 3906
            +F    PGG  +
Sbjct: 249  LFP---PGGVTK 257



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 47/215 (21%), Positives = 73/215 (33%), Gaps = 34/215 (15%)

Query: 3675 GRHEARPHSQPSSAPAMPKKGQPG--------YPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            GR      + P  +PA PK    G        +P S +   P+   ++     ++++  R
Sbjct: 266  GRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPR 325

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
            +            E  A  +   R   P P     P+S+  P  A   +P    + +   
Sbjct: 326  K------------EEGATKKAPSRLPLP-PSFHIRPASQVYPDRAP--EPDCPGELKATA 370

Query: 3787 LQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG-PSTATGPQPAGPP---RAEQT 3842
               P+        Q QSQ   R   P  + P   P P  P  A    PA PP     +  
Sbjct: 371  PASPRLG------QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARP 3877
            +   G  K P+   +P  +P P P      A + P
Sbjct: 425  HPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAP 458


>gi|239748855 PREDICTED: chromosome 6 open reading frame 132 [Homo
           sapiens]
          Length = 1188

 Score = 85.5 bits (210), Expect = 9e-16
 Identities = 183/787 (23%), Positives = 275/787 (34%), Gaps = 112/787 (14%)

Query: 14  GPLPPGGAG-----PGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVP---GPGP 65
           G L PG  G     P P PGP PG  +  S P GG  LP   +  STA PP P    P P
Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLP---SPPSTAPPPPPLLLEPPP 182

Query: 66  GPGPGPGPGSTSRRLDPKEPLGNQR----------------AASPTPKQASATTPGHESP 109
            P   P P      L P   L +                   A P P   +   P   SP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 110 RE--TRAQGPAG---QEADGPRRTLQVDSRTQRSGRSPSVSPDR--GSTPTSPYSVPQIA 162
               TR   P G    ++D      Q ++      RSP+       G  P    + P+  
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSF 302

Query: 163 PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222
            +P  T  P+ +TS +    +Q           K  ++    P+ H+    +        
Sbjct: 303 KVPPPT--PV-RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE 359

Query: 223 QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282
               G    TAP S    Q  S A   A +P   P   P       P  P P        
Sbjct: 360 PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPP-------PAPPLPPPAPPLPP 412

Query: 283 RATSVPGPAQAAAPPEVGRVSPQPPQPT-KPSTAEPRPPAGEAPAKSATAVPAGLGATEQ 341
            A  +P   +AA PP     +P+   P  KP   +P PP+ E  A SA          E+
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKP---KPNPPSPENTASSAPVDWRDPSQMEK 469

Query: 342 TQEGLTGKLFGLGAS---LLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
            +  L   L G       L  +    ++ Q +   +G   P K T   + +  +K+  P 
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET---LLSLPAKDTPPG 526

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
                 G       +  P   +        +P+   T S +  R E +A   +AA+ +  
Sbjct: 527 VPEKSLGGSSLTETEAAPSLTL---PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK 583

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
           P             ++GS  P         RL+   +C        + K     L  Q+ 
Sbjct: 584 P-------------SIGSLPPKP-------RLEGGRICENGADDDKLSKPVAKNLPPQST 623

Query: 519 RLLEGSLGEP-----TPLPPPTSQQPPVGAPHRAS---GTSPLKQKGP----QGLGQPSG 566
            LL  +  +P       +PP  + +P +  P +A+    T P    GP    +    P+ 
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKATSGPTT 681

Query: 567 PLPAKASP-LSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE 625
           PL A + P +++ A+ LP+  S Q    + S P+  P     ++   P++A        E
Sbjct: 682 PLKATSGPAIASTATTLPTTTS-QLMAEKDSGPAGQPEKPASQEVSTPSQAR------GE 734

Query: 626 TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ------S 679
            +P+ AT     G R +    P       +P GGE   L  KP+   +S S +      +
Sbjct: 735 GSPSEATRLPTQGARSSAAFPP-----KTSPGGGEVPCLY-KPHCHQSSLSREVAVVMPT 788

Query: 680 LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQG 739
           L+  G +  G      E  G+  +             HP +  E+ + GS M  LL A+ 
Sbjct: 789 LARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT-GEVVERGSPMALLLAARQ 847

Query: 740 LAPSERS 746
            A   RS
Sbjct: 848 RAQKGRS 854



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 85/340 (25%), Positives = 124/340 (36%), Gaps = 53/340 (15%)

Query: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418
            +P  P   S+  G     G   P+  + AP P  L    + P  P      P P   A S
Sbjct: 147  APGPPQDISEPPG-----GSPLPSPPSTAPPPPPL---LLEPPPPPSMAPPPPPVLEALS 198

Query: 1419 YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP 1478
              H+ ++ +  +  + +P AP     A  A    P+ A       P P+  ++      P
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPP---LAFLAPPPPPVPAP----APPAPASPHTVGTRLFP 251

Query: 1479 PLSPSS----------PSESPTFSPGKMGPRATAE--FSTQTPSPAPASDMPRSPGAPTP 1526
            P   +            +E+   SP    PR+ AE   S   P+P P    PRS   P P
Sbjct: 252  PGGVTKWKSDVALNGRQAEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307

Query: 1527 SPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTE 1586
            +P+             PR   + ++++AP  +    S        V+   +  P C P E
Sbjct: 308  TPVRTSSIPVQEAQEAPRKE-EGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC-PGE 365

Query: 1587 TQPTTH-----GYSQ--------TTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWG 1633
             + T       G SQ        T PP+    PP PP PP  P +P A    PL      
Sbjct: 366  LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--PLPCAQKA 423

Query: 1634 ALPAENISLCRISSVPGTSRVEPGPRTP----GTAVVDLR 1669
            A P    +    SS P   + +P P +P     +A VD R
Sbjct: 424  AHPPAGFTKTPKSSSPAL-KPKPNPPSPENTASSAPVDWR 462



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 71/334 (21%), Positives = 116/334 (34%), Gaps = 40/334 (11%)

Query: 1308 LTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSAS 1367
            L P   P    AP +   P S  + G R+ P   VT+  +    +  +  ++ ASP  + 
Sbjct: 224  LAPPPPPVPAPAPPA---PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280

Query: 1368 KE---------------IGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGS-ERSPS 1411
             E                   F   P TP  T+  P    +      P    G+ +++PS
Sbjct: 281  AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP----VQEAQEAPRKEEGATKKAPS 336

Query: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAARE--KPLSASDGEGGTPQPSRA 1469
                  S+   P +  Y  +  + P  P  L A   A+    +  S +D   GTP P+  
Sbjct: 337  RLPLPPSFHIRPASQVYPDRAPE-PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                A   PP +P  P  +P     +      A F+    S +PA  +   P  P+P   
Sbjct: 396  LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA--LKPKPNPPSPE-- 451

Query: 1530 VAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQP 1589
                    +  S+  + W++ SQ         A    S+      S    P  +P +++ 
Sbjct: 452  --------NTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP-QSKE 502

Query: 1590 TTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGA 1623
               G       ++  LP +   PPG P     G+
Sbjct: 503  GKKGPRLPEKETLLSLPAKDT-PPGVPEKSLGGS 535



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 54/207 (26%), Positives = 71/207 (34%), Gaps = 37/207 (17%)

Query: 3042 PATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPG---- 3097
            P T S P+    P F PPAP  +  +  P     PA  AP    P T     FPPG    
Sbjct: 200  PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTK 257

Query: 3098 ----------------ASYPAEPGLPNQQAFRP------TGHYAGQTPMPT-TQSTLFPV 3134
                            AS P  P  P   A  P      T   + + P PT  +++  PV
Sbjct: 258  WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317

Query: 3135 PADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV-----PMSSAPSETSYSGPAVSS-G 3188
                 AP ++   T  A     +P ++ +  +  V     P    P E   + PA    G
Sbjct: 318  QEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLG 377

Query: 3189 YEQGKVPEVPRAGDRGSVSQSPAPTYP 3215
              Q +  E  RAG        P P  P
Sbjct: 378  QSQSQADE--RAGTPPPAPPLPPPAPP 402



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 42/175 (24%), Positives = 63/175 (36%), Gaps = 13/175 (7%)

Query: 2198 INTPIAATLP---ITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLG 2254
            ++ P+A  LP    T  P + L+P    G   P  +    A+P    T  P   P+  LG
Sbjct: 610  LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP-PKATLWPATPPKATLG 668

Query: 2255 PTGLYRYPAPSRFPIASSVPPAEG------PVYLGKPAAAKAPGAGGPSRPEMPVGAARE 2308
            P    +  +    P+ ++  PA        P    +  A K  G  G  +PE P      
Sbjct: 669  PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG--QPEKPASQEVS 726

Query: 2309 EPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGS-GALSRPGFEKEEASQE 2362
             P       +  EA   P     +    P   +PGGG    L +P   +   S+E
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 90/389 (23%), Positives = 127/389 (32%), Gaps = 73/389 (18%)

Query: 1294 ESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
            + A   P K+ G       +P++L  P SF    +S     +V PD       A E   P
Sbjct: 318  QEAQEAPRKEEGATKK---APSRLPLPPSFHIRPAS-----QVYPDR------APEPDCP 363

Query: 1354 LKLHSS-PASP------SSASKEIG-------MPFSQGPGTPATTAVAPCPAGLPRGYMT 1399
             +L ++ PASP      S A +  G       +P    P  P    + P    LP     
Sbjct: 364  GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKA 423

Query: 1400 PASPAGSERSPSPSSTAHSYGHSPTT-------------------------ANY--GSQT 1432
               PAG  ++P  SS A     +P +                         A Y  GS+ 
Sbjct: 424  AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483

Query: 1433 ED-----------LPQAPSGLAAAGRAAREKPLS--ASDGEGGTPQPSRAYSYFASS--S 1477
            ED            PQ+  G        +E  LS  A D   G P+ S   S    +  +
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 1478 PPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTP 1537
            P L+  S    P  SP     +   E   +  S A     P S G+  P P +  G    
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICE 602

Query: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQT 1597
            +     +L  +  ++  P    TL    S Q + +   A   P  +P    P        
Sbjct: 603  NGADDDKLS-KPVAKNLPPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKATLWPA 660

Query: 1598 TPPSVSQLPPEPPGPPGFPRVPSAGADGP 1626
            TPP  +  P  P      P  P     GP
Sbjct: 661  TPPKATLGPATPLKATSGPTTPLKATSGP 689



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 59/248 (23%), Positives = 81/248 (32%), Gaps = 48/248 (19%)

Query: 2713 GESLACQTEPDGQAQGV--------AGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD 2764
            G+ L     P G A G          G  L  P + +P  P + +  P P        P 
Sbjct: 134  GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP----PSMAPP 189

Query: 2765 PLEIGYQAHLPPESLSQ---------------LVSRQPPKSPQVLYSPVSPLSPH----R 2805
            P  +  +A  PP +LS                L    PP  P    +P +P SPH    R
Sbjct: 190  PPPV-LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 2806 LLD----TSFASSERLN-----KAHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPL 2856
            L      T + S   LN         SP +             P P  T  RS   P P 
Sbjct: 249  LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308

Query: 2857 S-PTAEESAKERFSLYQHQGGLGSQVSA---LPPNSLVRKVKRTLPSPPPE---EAHLPL 2909
               T+    +E     + + G   +  +   LPP+  +R   +  P   PE      L  
Sbjct: 309  PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368

Query: 2910 AGQASPQL 2917
               ASP+L
Sbjct: 369  TAPASPRL 376



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 52/196 (26%), Positives = 74/196 (37%), Gaps = 27/196 (13%)

Query: 3028 PAGQFVDFPATAAAPATPSG--PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            PA Q   +P  A  P  P     TA   PR      Q    +G P     PA   P    
Sbjct: 348  PASQV--YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP----PAPPLPPPAP 401

Query: 3086 PSTYPAPAFPPGASYPAEPGLP-NQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQK 3144
            P   PAP  PP A     P LP  Q+A  P    AG T  P + S   P       P   
Sbjct: 402  PLPPPAPPLPPAA-----PPLPCAQKAAHPP---AGFTKTPKSSS---PALKPKPNPPSP 450

Query: 3145 PRQTSLADLEQKVPTNYEVIASPVVP-MSSAPSETSY----SGPAVSSGYEQGKVPEVPR 3199
                S A ++ + P+  E + + +   +  +  E  +     GP V+   ++GK  + PR
Sbjct: 451  ENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK--KGPR 508

Query: 3200 AGDRGSVSQSPAPTYP 3215
              ++ ++   PA   P
Sbjct: 509  LPEKETLLSLPAKDTP 524



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 36/132 (27%), Positives = 45/132 (34%), Gaps = 11/132 (8%)

Query: 3780 QQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---- 3835
            Q  Q L + PP         Q  S+P   G +P  S P+  P P P     P P      
Sbjct: 132  QYGQDLLIPPPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 3836 PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA-GQPGADGES 3894
            PP   +      T  +P     P   P P P  A +     P   P  PA   P   G  
Sbjct: 190  PPPVLEALSPPHTLSSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 3895 VFSKILPGGAAE 3906
            +F    PGG  +
Sbjct: 249  LFP---PGGVTK 257



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 47/215 (21%), Positives = 73/215 (33%), Gaps = 34/215 (15%)

Query: 3675 GRHEARPHSQPSSAPAMPKKGQPG--------YPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            GR      + P  +PA PK    G        +P S +   P+   ++     ++++  R
Sbjct: 266  GRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPR 325

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
            +            E  A  +   R   P P     P+S+  P  A   +P    + +   
Sbjct: 326  K------------EEGATKKAPSRLPLP-PSFHIRPASQVYPDRAP--EPDCPGELKATA 370

Query: 3787 LQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG-PSTATGPQPAGPP---RAEQT 3842
               P+        Q QSQ   R   P  + P   P P  P  A    PA PP     +  
Sbjct: 371  PASPRLG------QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARP 3877
            +   G  K P+   +P  +P P P      A + P
Sbjct: 425  HPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAP 458


>gi|239742884 PREDICTED: hypothetical protein LOC647024 [Homo
           sapiens]
          Length = 1188

 Score = 85.5 bits (210), Expect = 9e-16
 Identities = 183/787 (23%), Positives = 275/787 (34%), Gaps = 112/787 (14%)

Query: 14  GPLPPGGAG-----PGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVP---GPGP 65
           G L PG  G     P P PGP PG  +  S P GG  LP   +  STA PP P    P P
Sbjct: 126 GDLRPGQYGQDLLIPPPPPGPAPGPPQDISEPPGGSPLP---SPPSTAPPPPPLLLEPPP 182

Query: 66  GPGPGPGPGSTSRRLDPKEPLGNQR----------------AASPTPKQASATTPGHESP 109
            P   P P      L P   L +                   A P P   +   P   SP
Sbjct: 183 PPSMAPPPPPVLEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASP 242

Query: 110 RE--TRAQGPAG---QEADGPRRTLQVDSRTQRSGRSPSVSPDR--GSTPTSPYSVPQIA 162
               TR   P G    ++D      Q ++      RSP+       G  P    + P+  
Sbjct: 243 HTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSF 302

Query: 163 PLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQM 222
            +P  T  P+ +TS +    +Q           K  ++    P+ H+    +        
Sbjct: 303 KVPPPT--PV-RTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPE 359

Query: 223 QRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA 282
               G    TAP S    Q  S A   A +P   P   P       P  P P        
Sbjct: 360 PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPPLPP-------PAPPLPPPAPPLPP 412

Query: 283 RATSVPGPAQAAAPPEVGRVSPQPPQPT-KPSTAEPRPPAGEAPAKSATAVPAGLGATEQ 341
            A  +P   +AA PP     +P+   P  KP   +P PP+ E  A SA          E+
Sbjct: 413 AAPPLPCAQKAAHPPAGFTKTPKSSSPALKP---KPNPPSPENTASSAPVDWRDPSQMEK 469

Query: 342 TQEGLTGKLFGLGAS---LLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPK 398
            +  L   L G       L  +    ++ Q +   +G   P K T   + +  +K+  P 
Sbjct: 470 LRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGKKGPRLPEKET---LLSLPAKDTPPG 526

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
                 G       +  P   +        +P+   T S +  R E +A   +AA+ +  
Sbjct: 527 VPEKSLGGSSLTETEAAPSLTL---PSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAK 583

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
           P             ++GS  P         RL+   +C        + K     L  Q+ 
Sbjct: 584 P-------------SIGSLPPKP-------RLEGGRICENGADDDKLSKPVAKNLPPQST 623

Query: 519 RLLEGSLGEP-----TPLPPPTSQQPPVGAPHRAS---GTSPLKQKGP----QGLGQPSG 566
            LL  +  +P       +PP  + +P +  P +A+    T P    GP    +    P+ 
Sbjct: 624 TLLPTTSLQPKAMLGPAIPPKATPEPAI--PPKATLWPATPPKATLGPATPLKATSGPTT 681

Query: 567 PLPAKASP-LSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPE 625
           PL A + P +++ A+ LP+  S Q    + S P+  P     ++   P++A        E
Sbjct: 682 PLKATSGPAIASTATTLPTTTS-QLMAEKDSGPAGQPEKPASQEVSTPSQAR------GE 734

Query: 626 TTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQ------S 679
            +P+ AT     G R +    P       +P GGE   L  KP+   +S S +      +
Sbjct: 735 GSPSEATRLPTQGARSSAAFPP-----KTSPGGGEVPCLY-KPHCHQSSLSREVAVVMPT 788

Query: 680 LSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQG 739
           L+  G +  G      E  G+  +             HP +  E+ + GS M  LL A+ 
Sbjct: 789 LARGGAAGPGEPVEVKEPPGLPAKPPASAQPTDELLRHPVT-GEVVERGSPMALLLAARQ 847

Query: 740 LAPSERS 746
            A   RS
Sbjct: 848 RAQKGRS 854



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 85/340 (25%), Positives = 124/340 (36%), Gaps = 53/340 (15%)

Query: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418
            +P  P   S+  G     G   P+  + AP P  L    + P  P      P P   A S
Sbjct: 147  APGPPQDISEPPG-----GSPLPSPPSTAPPPPPL---LLEPPPPPSMAPPPPPVLEALS 198

Query: 1419 YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP 1478
              H+ ++ +  +  + +P AP     A  A    P+ A       P P+  ++      P
Sbjct: 199  PPHTLSSPSIPTPPDFIPPAPP---LAFLAPPPPPVPAP----APPAPASPHTVGTRLFP 251

Query: 1479 PLSPSS----------PSESPTFSPGKMGPRATAE--FSTQTPSPAPASDMPRSPGAPTP 1526
            P   +            +E+   SP    PR+ AE   S   P+P P    PRS   P P
Sbjct: 252  PGGVTKWKSDVALNGRQAEATRASP----PRSPAEPKGSALGPNPEPHLTFPRSFKVPPP 307

Query: 1527 SPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTE 1586
            +P+             PR   + ++++AP  +    S        V+   +  P C P E
Sbjct: 308  TPVRTSSIPVQEAQEAPRKE-EGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDC-PGE 365

Query: 1587 TQPTTH-----GYSQ--------TTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWG 1633
             + T       G SQ        T PP+    PP PP PP  P +P A    PL      
Sbjct: 366  LKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAP--PLPCAQKA 423

Query: 1634 ALPAENISLCRISSVPGTSRVEPGPRTP----GTAVVDLR 1669
            A P    +    SS P   + +P P +P     +A VD R
Sbjct: 424  AHPPAGFTKTPKSSSPAL-KPKPNPPSPENTASSAPVDWR 462



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 71/334 (21%), Positives = 116/334 (34%), Gaps = 40/334 (11%)

Query: 1308 LTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSAS 1367
            L P   P    AP +   P S  + G R+ P   VT+  +    +  +  ++ ASP  + 
Sbjct: 224  LAPPPPPVPAPAPPA---PASPHTVGTRLFPPGGVTKWKSDVALNGRQAEATRASPPRSP 280

Query: 1368 KE---------------IGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGS-ERSPS 1411
             E                   F   P TP  T+  P    +      P    G+ +++PS
Sbjct: 281  AEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIP----VQEAQEAPRKEEGATKKAPS 336

Query: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAARE--KPLSASDGEGGTPQPSRA 1469
                  S+   P +  Y  +  + P  P  L A   A+    +  S +D   GTP P+  
Sbjct: 337  RLPLPPSFHIRPASQVYPDRAPE-PDCPGELKATAPASPRLGQSQSQADERAGTPPPAPP 395

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPM 1529
                A   PP +P  P  +P     +      A F+    S +PA  +   P  P+P   
Sbjct: 396  LPPPAPPLPPPAPPLPPAAPPLPCAQKAAHPPAGFTKTPKSSSPA--LKPKPNPPSPE-- 451

Query: 1530 VAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQP 1589
                    +  S+  + W++ SQ         A    S+      S    P  +P +++ 
Sbjct: 452  --------NTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAP-QSKE 502

Query: 1590 TTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGA 1623
               G       ++  LP +   PPG P     G+
Sbjct: 503  GKKGPRLPEKETLLSLPAKDT-PPGVPEKSLGGS 535



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 54/207 (26%), Positives = 71/207 (34%), Gaps = 37/207 (17%)

Query: 3042 PATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPG---- 3097
            P T S P+    P F PPAP  +  +  P     PA  AP    P T     FPPG    
Sbjct: 200  PHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPA--SPHTVGTRLFPPGGVTK 257

Query: 3098 ----------------ASYPAEPGLPNQQAFRP------TGHYAGQTPMPT-TQSTLFPV 3134
                            AS P  P  P   A  P      T   + + P PT  +++  PV
Sbjct: 258  WKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPV 317

Query: 3135 PADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVV-----PMSSAPSETSYSGPAVSS-G 3188
                 AP ++   T  A     +P ++ +  +  V     P    P E   + PA    G
Sbjct: 318  QEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKATAPASPRLG 377

Query: 3189 YEQGKVPEVPRAGDRGSVSQSPAPTYP 3215
              Q +  E  RAG        P P  P
Sbjct: 378  QSQSQADE--RAGTPPPAPPLPPPAPP 402



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 42/175 (24%), Positives = 63/175 (36%), Gaps = 13/175 (7%)

Query: 2198 INTPIAATLP---ITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLG 2254
            ++ P+A  LP    T  P + L+P    G   P  +    A+P    T  P   P+  LG
Sbjct: 610  LSKPVAKNLPPQSTTLLPTTSLQPKAMLGPAIPPKATPEPAIP-PKATLWPATPPKATLG 668

Query: 2255 PTGLYRYPAPSRFPIASSVPPAEG------PVYLGKPAAAKAPGAGGPSRPEMPVGAARE 2308
            P    +  +    P+ ++  PA        P    +  A K  G  G  +PE P      
Sbjct: 669  PATPLKATSGPTTPLKATSGPAIASTATTLPTTTSQLMAEKDSGPAG--QPEKPASQEVS 726

Query: 2309 EPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGS-GALSRPGFEKEEASQE 2362
             P       +  EA   P     +    P   +PGGG    L +P   +   S+E
Sbjct: 727  TPSQARGEGSPSEATRLPTQGARSSAAFPPKTSPGGGEVPCLYKPHCHQSSLSRE 781



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 90/389 (23%), Positives = 127/389 (32%), Gaps = 73/389 (18%)

Query: 1294 ESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDP 1353
            + A   P K+ G       +P++L  P SF    +S     +V PD       A E   P
Sbjct: 318  QEAQEAPRKEEGATKK---APSRLPLPPSFHIRPAS-----QVYPDR------APEPDCP 363

Query: 1354 LKLHSS-PASP------SSASKEIG-------MPFSQGPGTPATTAVAPCPAGLPRGYMT 1399
             +L ++ PASP      S A +  G       +P    P  P    + P    LP     
Sbjct: 364  GELKATAPASPRLGQSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKA 423

Query: 1400 PASPAGSERSPSPSSTAHSYGHSPTT-------------------------ANY--GSQT 1432
               PAG  ++P  SS A     +P +                         A Y  GS+ 
Sbjct: 424  AHPPAGFTKTPKSSSPALKPKPNPPSPENTASSAPVDWRDPSQMEKLRNELAAYLCGSRR 483

Query: 1433 ED-----------LPQAPSGLAAAGRAAREKPLS--ASDGEGGTPQPSRAYSYFASS--S 1477
            ED            PQ+  G        +E  LS  A D   G P+ S   S    +  +
Sbjct: 484  EDRFLSHRPGPTVAPQSKEGKKGPRLPEKETLLSLPAKDTPPGVPEKSLGGSSLTETEAA 543

Query: 1478 PPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTP 1537
            P L+  S    P  SP     +   E   +  S A     P S G+  P P +  G    
Sbjct: 544  PSLTLPSVDYIPQDSPTPSVRQIRNELEARLSSAAEKEAKP-SIGSLPPKPRLEGGRICE 602

Query: 1538 HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQT 1597
            +     +L  +  ++  P    TL    S Q + +   A   P  +P    P        
Sbjct: 603  NGADDDKLS-KPVAKNLPPQSTTLLPTTSLQPKAMLGPA-IPPKATPEPAIPPKATLWPA 660

Query: 1598 TPPSVSQLPPEPPGPPGFPRVPSAGADGP 1626
            TPP  +  P  P      P  P     GP
Sbjct: 661  TPPKATLGPATPLKATSGPTTPLKATSGP 689



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 59/248 (23%), Positives = 81/248 (32%), Gaps = 48/248 (19%)

Query: 2713 GESLACQTEPDGQAQGV--------AGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD 2764
            G+ L     P G A G          G  L  P + +P  P + +  P P        P 
Sbjct: 134  GQDLLIPPPPPGPAPGPPQDISEPPGGSPLPSPPSTAPPPPPLLLEPPPP----PSMAPP 189

Query: 2765 PLEIGYQAHLPPESLSQ---------------LVSRQPPKSPQVLYSPVSPLSPH----R 2805
            P  +  +A  PP +LS                L    PP  P    +P +P SPH    R
Sbjct: 190  PPPV-LEALSPPHTLSSPSIPTPPDFIPPAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 2806 LLD----TSFASSERLN-----KAHVSPQKHFTADSALRQQTLPRPMKTLQRSLSDPKPL 2856
            L      T + S   LN         SP +             P P  T  RS   P P 
Sbjct: 249  LFPPGGVTKWKSDVALNGRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPT 308

Query: 2857 S-PTAEESAKERFSLYQHQGGLGSQVSA---LPPNSLVRKVKRTLPSPPPE---EAHLPL 2909
               T+    +E     + + G   +  +   LPP+  +R   +  P   PE      L  
Sbjct: 309  PVRTSSIPVQEAQEAPRKEEGATKKAPSRLPLPPSFHIRPASQVYPDRAPEPDCPGELKA 368

Query: 2910 AGQASPQL 2917
               ASP+L
Sbjct: 369  TAPASPRL 376



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 52/196 (26%), Positives = 74/196 (37%), Gaps = 27/196 (13%)

Query: 3028 PAGQFVDFPATAAAPATPSG--PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            PA Q   +P  A  P  P     TA   PR      Q    +G P     PA   P    
Sbjct: 348  PASQV--YPDRAPEPDCPGELKATAPASPRLGQSQSQADERAGTPP----PAPPLPPPAP 401

Query: 3086 PSTYPAPAFPPGASYPAEPGLP-NQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQK 3144
            P   PAP  PP A     P LP  Q+A  P    AG T  P + S   P       P   
Sbjct: 402  PLPPPAPPLPPAA-----PPLPCAQKAAHPP---AGFTKTPKSSS---PALKPKPNPPSP 450

Query: 3145 PRQTSLADLEQKVPTNYEVIASPVVP-MSSAPSETSY----SGPAVSSGYEQGKVPEVPR 3199
                S A ++ + P+  E + + +   +  +  E  +     GP V+   ++GK  + PR
Sbjct: 451  ENTASSAPVDWRDPSQMEKLRNELAAYLCGSRREDRFLSHRPGPTVAPQSKEGK--KGPR 508

Query: 3200 AGDRGSVSQSPAPTYP 3215
              ++ ++   PA   P
Sbjct: 509  LPEKETLLSLPAKDTP 524



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 36/132 (27%), Positives = 45/132 (34%), Gaps = 11/132 (8%)

Query: 3780 QQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG---- 3835
            Q  Q L + PP         Q  S+P   G +P  S P+  P P P     P P      
Sbjct: 132  QYGQDLLIPPPPPGPAPGPPQDISEPP--GGSPLPSPPSTAPPPPPLLLEPPPPPSMAPP 189

Query: 3836 PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA-GQPGADGES 3894
            PP   +      T  +P     P   P P P  A +     P   P  PA   P   G  
Sbjct: 190  PPPVLEALSPPHTLSSPSIPTPPDFIP-PAPPLAFLAPPPPPVPAPAPPAPASPHTVGTR 248

Query: 3895 VFSKILPGGAAE 3906
            +F    PGG  +
Sbjct: 249  LFP---PGGVTK 257



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 47/215 (21%), Positives = 73/215 (33%), Gaps = 34/215 (15%)

Query: 3675 GRHEARPHSQPSSAPAMPKKGQPG--------YPSSAEYSQPSRASSAYHHASDSKKGSR 3726
            GR      + P  +PA PK    G        +P S +   P+   ++     ++++  R
Sbjct: 266  GRQAEATRASPPRSPAEPKGSALGPNPEPHLTFPRSFKVPPPTPVRTSSIPVQEAQEAPR 325

Query: 3727 QAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLG 3786
            +            E  A  +   R   P P     P+S+  P  A   +P    + +   
Sbjct: 326  K------------EEGATKKAPSRLPLP-PSFHIRPASQVYPDRAP--EPDCPGELKATA 370

Query: 3787 LQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPG-PSTATGPQPAGPP---RAEQT 3842
               P+        Q QSQ   R   P  + P   P P  P  A    PA PP     +  
Sbjct: 371  PASPRLG------QSQSQADERAGTPPPAPPLPPPAPPLPPPAPPLPPAAPPLPCAQKAA 424

Query: 3843 NGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARP 3877
            +   G  K P+   +P  +P P P      A + P
Sbjct: 425  HPPAGFTKTPKSS-SPALKPKPNPPSPENTASSAP 458


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 83.2 bits (204), Expect = 5e-15
 Identities = 152/689 (22%), Positives = 218/689 (31%), Gaps = 133/689 (19%)

Query: 9   GGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPG 68
           GG G   +P      GP    G  +  P S P   G+   A  A++T+  PV  PG   G
Sbjct: 63  GGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122

Query: 69  -PGPGP-GSTSRRLDPKEPLGNQRAASPTPKQA---------SATTPGHESPRETRAQGP 117
              PGP G    R+  +E +   +A     + A         S  TPG  SP   R    
Sbjct: 123 TTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 118 AGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTL-CPICKTS 176
           AG E   PR       R    G   SVS     + T P    +  P     L  P  ++ 
Sbjct: 183 AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSL 242

Query: 177 DLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRS 236
             ++TP              + +     P+   T             RA      + P+ 
Sbjct: 243 SSSATP--------------LSSPARSGPSARGT------------PRAPA--HPSQPKP 274

Query: 237 KSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAP 296
           K  Q L  P ++P    A   LG      S     P P +     A  T    P  ++  
Sbjct: 275 KGLQALRPPQVTPPRKDAAPALGPLS---SSPLATPSPSAALQSQAPPTLPATPHSSSLT 331

Query: 297 PEVGRVSP-QPPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGL 353
            ++    P  PP P+ P + +  P PPA   P+++ T++  G    + T   L       
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPA-TPPSQATTSL--GSPTLQATHSFLPSPPLSP 388

Query: 354 GASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP-GPGPAPGA 412
            A+   QA   +++ P       PA    +P    +  +  A    L   P  P P+P  
Sbjct: 389 LATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPV 448

Query: 413 KTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAEL 472
           +        P S P + P +   T P       QA    AA P  +P      P      
Sbjct: 449 Q-------APFSPPASPPVSPSATPPS------QAPPSLAAPPLQVPPSPPASPPMSPSA 495

Query: 473 NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLP 532
               ++P                      P L      L               +P P  
Sbjct: 496 TPPPQAP----------------------PPLAAPPLQL--------------AKPPPQA 519

Query: 533 PPTSQQPPVGA----PHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASP 588
           PP    PP+ A    P    G +P                P+ + P+S  A+P P     
Sbjct: 520 PPALATPPLQALPSPPASFPGQAPFS--------------PSASLPMSPLATPPPQAPPV 565

Query: 589 QAKPLRASEPSKTPSSVQEKKTRVPTKA--------------EPMPKPPPETTP--TPAT 632
            A PL    PS   S   +   R PT                 P P PPP  +P  T + 
Sbjct: 566 LAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSG 625

Query: 633 PKVKSGVRRAEPATPVVKAVPEAPKGGEA 661
           P +      A      ++     P+GG A
Sbjct: 626 PDLAGHSSSATSTPEELRGYDSGPEGGAA 654



 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 173/767 (22%), Positives = 254/767 (33%), Gaps = 155/767 (20%)

Query: 15  PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
           P PPG   P P P   P A +   A    G+ P A  A       +P   P  GP    G
Sbjct: 27  PRPPGS--PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAG 84

Query: 75  STSRRLDPKEPLGNQRAASPTPKQAS---ATTPGHESPRETRAQGPAGQE---------- 121
           ++SR    + P   +   +P  K  S    ++PG  S   T   GP GQ+          
Sbjct: 85  TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRAS--GTTRPGPLGQKGLRISAEETV 142

Query: 122 -----ADGPRRT-LQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKT 175
                 + P+R+ L   +R   SG +P       +  +         P P+ +  P   T
Sbjct: 143 ARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 202

Query: 176 SDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPR 235
                + S  + ++ T+            P+P               +R         P 
Sbjct: 203 EGPRKSVSSASEHSTTE------------PSP------------AARRRPSAGGGLQRPA 238

Query: 236 SKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGP-QPGSRQAETARATSVPGPAQAA 294
           S+S     +P  SPA S      G   +   R P  P QP  +  +  R   V  P + A
Sbjct: 239 SRSLSSSATPLSSPARS------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDA 292

Query: 295 APPEVGRVSPQPPQPTKPSTA-EPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGL 353
           A P +G +S  P     PS A + + P    P   AT   + L     T   L       
Sbjct: 293 A-PALGPLSSSPLATPSPSAALQSQAP----PTLPATPHSSSLTCQLATPLPLAPPSPSA 347

Query: 354 GASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP-KPLGSGPGPGPAPGA 412
             SL T  S      P A    Q   S G+P +    +   + P  PL + P   P   A
Sbjct: 348 PPSLQTLPS------PPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401

Query: 413 KTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAEL 472
                A   P + P   P    T SP       QA +  A      P      P  QA  
Sbjct: 402 LPPLQAPPSPPASPPLSPL--ATPSP-------QAPNALAVHLLQAPFSPPPSPPVQAPF 452

Query: 473 NVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLP 532
           +  +  P + +                                            P    
Sbjct: 453 SPPASPPVSPS------------------------------------------ATPPSQA 470

Query: 533 PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKP 592
           PP+   PP+  P     + P+    P     P  P P  A PL        +K  PQA P
Sbjct: 471 PPSLAAPPLQVPPSPPASPPM---SPSATPPPQAPPPLAAPPLQL------AKPPPQAPP 521

Query: 593 LRASEPSKT----PSSVQEKKTRVPTKA---EPMPKPPPETTPTPATPKVKSGVRRAEPA 645
             A+ P +     P+S   +    P+ +    P+  PPP+  P  A P ++  V  + PA
Sbjct: 522 ALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ--VPPSPPA 579

Query: 646 TPVVKAVPEAPKGGEAEDLVGKPYS--------QDASRSPQSLSDTGYSSDGISSSQSEI 697
           +P ++A    P  G    + G   +           SRSP S + +G    G SSS +  
Sbjct: 580 SPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSS-TLSGPDLAGHSSSATS- 637

Query: 698 TGVVQQEVEQLDSA--GVTGPHPPSPSEIHKVGSSMRPLLQAQGLAP 742
                +E+   DS   G     PP  +E+    ++  P   ++G AP
Sbjct: 638 ---TPEELRGYDSGPEGGAAASPPPDAEL----AACHPAAWSRGPAP 677



 Score = 72.4 bits (176), Expect = 8e-12
 Identities = 168/744 (22%), Positives = 244/744 (32%), Gaps = 124/744 (16%)

Query: 973  DRSRGEHSSTLPASTPSYTSGTSPT-SLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHG 1031
            +R+ G   +T+P S P       PT S  +   +  S P    R E A     A++ S G
Sbjct: 60   ERAGGIGGATIPESAPR----AGPTRSAGTSSRNPASRPPASGRGERAPP---AKNTSPG 112

Query: 1032 PLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSK 1091
            P+      SS              Q+ +R   ++ +          +  L A  RR+ S 
Sbjct: 113  PV------SSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 166

Query: 1092 TPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYS-PSPSLDSEAEALDGGPSRLYKSG 1150
              P   SP               M    R++ +E   P P+  +       GP +   S 
Sbjct: 167  PTPGTPSPA--------------MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSA 212

Query: 1151 SEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARG 1210
            SE+         S TE    +   PS+G  L+    A   +   A  L         ARG
Sbjct: 213  SEH---------STTEPSPAARRRPSAGGGLQ--RPASRSLSSSATPLSSPARSGPSARG 261

Query: 1211 PHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRM 1270
                P+ P+ P+  G    +        Q   P  +  PA LG      +   S S    
Sbjct: 262  TPRAPAHPSQPKPKGLQALRPP------QVTPPRKDAAPA-LGPLSSSPLATPSPSAALQ 314

Query: 1271 RQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSD 1330
             QA     A           L  + A   P+     P +P   P+    P   +TP S  
Sbjct: 315  SQAPPTLPATPHSSS-----LTCQLATPLPL----APPSPSAPPSLQTLPSPPATPPSQA 365

Query: 1331 SSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCP 1390
            ++     P ++ T  F      PL   ++P  P  A   + +P  Q P +P        P
Sbjct: 366  TTS-LGSPTLQATHSFLPSP--PLSPLATP--PPQAPPALALPPLQAPPSP--------P 412

Query: 1391 AGLPRGYMTPASPAGSER----------SPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
            A  P   +   SP               SP PS    +    P +           QAP 
Sbjct: 413  ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPP 472

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFS--PGKMGP 1498
             LAA        P ++         P +A    A+    L+   P   P  +  P +  P
Sbjct: 473  SLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 532

Query: 1499 RATAEFSTQTPSPAPASDMPRSP------------GAPT----PSPMVAQGTQTPHRPST 1542
               A F  Q P  +P++ +P SP             AP     PSP  +   Q P RP T
Sbjct: 533  SPPASFPGQAPF-SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591

Query: 1543 PRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSP-----LCSPTETQPTTHGY-SQ 1596
            P     ++S   P + + LA           +S  + P       S T T     GY S 
Sbjct: 592  P---GPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSG 648

Query: 1597 TTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYG-------W--GALPAENISLCRI-- 1645
                + +  PP+       P   S G   PLA  G       W     P     LC I  
Sbjct: 649  PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 708

Query: 1646 -----SSVPGTSRVEPGPRTPGTA 1664
                 S+ P    ++PGP +PGT+
Sbjct: 709  TEGPESATPAPGALDPGP-SPGTS 731



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 148/632 (23%), Positives = 204/632 (32%), Gaps = 158/632 (25%)

Query: 1068 RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASP-------------TEELRQAAE 1114
            RS    +R       A  R ER+  P  N SP   +SP              + LR +AE
Sbjct: 81   RSAGTSSRNPASRPPASGRGERAP-PAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE 139

Query: 1115 MEELHRSSCSEYSPSPSLDSEAEALDGGPS----------RLYKSGSEYNLPTFMSLYSP 1164
             E + R   +E     +L + A     GP+          R   +G+E  LP        
Sbjct: 140  -ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR------- 191

Query: 1165 TETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGL 1224
               PS     P+ G P KS   A E           +   AA  R   GG  Q    R L
Sbjct: 192  -PAPSARPRPPTEG-PRKSVSSASEHSTT-------EPSPAARRRPSAGGGLQRPASRSL 242

Query: 1225 GSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDK 1284
             S      T       + P+A GTP +                             ++ K
Sbjct: 243  SS----SATPLSSPARSGPSARGTPRAPAHP-------------------------SQPK 273

Query: 1285 KKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQ 1344
             K  Q L      + P +++  P     S + LA P    +P++                
Sbjct: 274  PKGLQALRPPQ--VTPPRKDAAPALGPLSSSPLATP----SPSA---------------- 311

Query: 1345 HFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPA 1404
              A ++Q P  L ++P S SS + ++  P    P +P+     P    LP    TP S A
Sbjct: 312  --ALQSQAPPTLPATPHS-SSLTCQLATPLPLAPPSPSAP---PSLQTLPSPPATPPSQA 365

Query: 1405 GSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTP 1464
             +          HS+  SP  +   +     PQAP  LA         PL A        
Sbjct: 366  TTSLGSPTLQATHSFLPSPPLSPLATPP---PQAPPALALP-------PLQA-------- 407

Query: 1465 QPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAP 1524
                         PP  P+SP  SP  +P    P A A    Q P   P S   ++P +P
Sbjct: 408  -------------PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454

Query: 1525 TPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSP 1584
              SP V+     P             SQ  P +        ++    V  S   SP  SP
Sbjct: 455  PASPPVSPSATPP-------------SQAPPSL--------AAPPLQVPPSPPASPPMSP 493

Query: 1585 TETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCR 1644
            + T P         PP     PP P  PP     P      P A +  G  P        
Sbjct: 494  SATPPPQAPPPLAAPPLQLAKPP-PQAPPALATPPLQALPSPPASFP-GQAP-----FSP 546

Query: 1645 ISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP 1676
             +S+P +    P P+ P      L   V P+P
Sbjct: 547  SASLPMSPLATPPPQAPPVLAAPL-LQVPPSP 577



 Score = 64.3 bits (155), Expect = 2e-09
 Identities = 167/719 (23%), Positives = 216/719 (30%), Gaps = 113/719 (15%)

Query: 3   NEVSLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQ----------------- 45
           N  S    +G G   P      PGP   PG     + P   GQ                 
Sbjct: 89  NPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKAT 148

Query: 46  -LPAAGAARSTAVPPVPGPGPG-PGPG--------------PGPGSTSRRLDPKEPLGNQ 89
             P   A  + A     GP PG P P               P P  ++R   P+ P    
Sbjct: 149 EAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSAR---PRPPTEGP 205

Query: 90  RAASPTPKQASATTPGHESPRETRAQG----PAGQEADGPRRTLQVDSRTQRSGRSPSVS 145
           R +  +  + S T P   + R   A G    PA +        L   +R+  S R    +
Sbjct: 206 RKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA 265

Query: 146 PDRGSTP----TSPYSVPQIAPLPSSTLCPICKTSDLTSTP-SQPNFNTCTQCHNKVCNQ 200
           P   S P          PQ+ P P     P      L+S+P + P+ +   Q        
Sbjct: 266 PAHPSQPKPKGLQALRPPQVTP-PRKDAAP--ALGPLSSSPLATPSPSAALQS------- 315

Query: 201 CGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGK 260
                 P L        L CQ+   L +   +     S Q L SP  +P  S A   LG 
Sbjct: 316 ---QAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPP-SQATTSLGS 371

Query: 261 PDQERSRG--PGGPQPGSRQAETARATSVP-GPAQAAAPPEVGRVSPQPPQPTKPSTAEP 317
           P  + +    P  P        +  AT  P  P   A PP     SP    P  P  A P
Sbjct: 372 PTLQATHSFLPSPPL-------SPLATPPPQAPPALALPPLQAPPSPPASPPLSP-LATP 423

Query: 318 RPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQP 377
            P A  A A      P     +   Q           A     AS    V P A    Q 
Sbjct: 424 SPQAPNALAVHLLQAPFSPPPSPPVQ-----------APFSPPASP--PVSPSATPPSQA 470

Query: 378 APSKGTPKIVFNDASKEAGP-KPLGSGPGPGPAPGAKTEPGARMGPGSGPGAL--PKTGG 434
            PS   P +    +   + P  P  + P   P P A         P   P AL  P    
Sbjct: 471 PPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQA 530

Query: 435 TTSPK---HGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQ 491
             SP     G+A    ++     P   P  +A   L    L V    PA+       R  
Sbjct: 531 LPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR-- 588

Query: 492 VCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTS 551
                   PTP          L   T  L  G    P+  P  T   P + A H +S TS
Sbjct: 589 -------PPTPGPDTSVSGPRL---TLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATS 637

Query: 552 PLKQ-----KGPQGLGQPSGPLP----AKASPLSTKASPLPSKASPQAKPLRASEPSKT- 601
             ++      GP+G G  + P P    A   P +    P P  A   A       P  T 
Sbjct: 638 TPEELRGYDSGPEG-GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG 696

Query: 602 PSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE 660
           P S     T   T+      P P       +P    G   A          P+  + GE
Sbjct: 697 PGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 65/239 (27%), Positives = 91/239 (38%), Gaps = 14/239 (5%)

Query: 532 PPPTSQQP-PVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQA 590
           PP  +  P PV +P RASGT+   + GP  LGQ    + A+ +    KA+  P +++  A
Sbjct: 104 PPAKNTSPGPVSSPGRASGTT---RPGP--LGQKGLRISAEETVARGKATEAPKRSALSA 158

Query: 591 KPLR-ASEPSK-TPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPV 648
              R  S P+  TPS    +++R       +P+P P   P P T   +  V  A      
Sbjct: 159 GARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASE---- 214

Query: 649 VKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQL 708
             +  E           G    + ASRS  S S T  SS   S   +  T        Q 
Sbjct: 215 -HSTTEPSPAARRRPSAGGGLQRPASRSLSS-SATPLSSPARSGPSARGTPRAPAHPSQP 272

Query: 709 DSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSIT 767
              G+    PP  +   K  +     L +  LA    S  L S         PHS S+T
Sbjct: 273 KPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 103/412 (25%), Positives = 133/412 (32%), Gaps = 65/412 (15%)

Query: 23  PGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDP 82
           P P P        P S P      P + A  S A PP+  P P P   P P S S    P
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSPPASP-PMSPSATPPP 499

Query: 83  KEP----LGNQRAASPTPKQASA-TTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQR 137
           + P        + A P P+   A  TP  ++     A  P GQ    P  +L +      
Sbjct: 500 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPM------ 552

Query: 138 SGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKV 197
              SP  +P   + P     + Q+ P P     P   T      P  P  +T        
Sbjct: 553 ---SPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRPPTPGPDTSVS----- 599

Query: 198 CNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQP 257
                    P LT              AL       P       L  P L+  HS +   
Sbjct: 600 --------GPRLTL-------------ALAPGPPPPPSRSPSSTLSGPDLA-GHSSSATS 637

Query: 258 LGKPDQERSRGPGGPQPGSRQAETARATSVPGP-AQAAAPPEVGRVSPQPPQPTKPSTAE 316
             +  +    GP G    S   +   A   P   ++  APP   R +P  P P  P+T  
Sbjct: 638 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG- 696

Query: 317 PRPPAG-------EAPAKSATAVPAGL--GATEQTQEGLTGKLFGLGASLLTQASTLMSV 367
           P    G       E P +SAT  P  L  G +  T  G      G GAS  +     +  
Sbjct: 697 PGSADGLCTIYETEGP-ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 755

Query: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGAR 419
            P    Q        +  ++   A   AG    GSG GPG A G     GAR
Sbjct: 756 LPLGALQASVVQHLLSRTLLLAAAEGAAG----GSGGGPGGAEGGGVTGGAR 803



 Score = 51.6 bits (122), Expect = 2e-05
 Identities = 68/272 (25%), Positives = 94/272 (34%), Gaps = 46/272 (16%)

Query: 3635 GPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKK 3694
            GP R A             SGR     P +  +       GR        P         
Sbjct: 78   GPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPL-------- 129

Query: 3695 GQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPA--------ALQSKAE------ 3740
            GQ G   SAE +     ++     S    G+R+  SGP         A +S+A       
Sbjct: 130  GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGL 189

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQI---PSGAASRQPQTQQQQQGLGLQPP-----QQ 3792
            P+  P  + R    GP++S S +S      PS AA R+P       G GLQ P       
Sbjct: 190  PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA-----GGGLQRPASRSLSS 244

Query: 3793 ALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAP 3852
            + T      +S P+ RG+  A + P+ +P+P    A  P    PPR +          AP
Sbjct: 245  SATPLSSPARSGPSARGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKD---------AAP 294

Query: 3853 QQGRAPQAQPAPGPGPAGVKAGARPGGTPGAP 3884
              G    + P   P P+       P   P  P
Sbjct: 295  ALGPL-SSSPLATPSPSAALQSQAPPTLPATP 325



 Score = 49.7 bits (117), Expect = 6e-05
 Identities = 138/614 (22%), Positives = 198/614 (32%), Gaps = 125/614 (20%)

Query: 1385 AVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAA 1444
            A A  PA    G +TP  P GS R P P +                     P A   L A
Sbjct: 12   AAARTPAARAPGLLTPRPP-GSPRPPPPVT---------------------PAALRVLGA 49

Query: 1445 AGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEF 1504
            AG   R+     + G GG   P  A      + P  S  + S +P   P   G    A  
Sbjct: 50   AGAVGRKPLAERAGGIGGATIPESA----PRAGPTRSAGTSSRNPASRPPASGRGERAPP 105

Query: 1505 STQTPSPAPASDMPRSPGAPTPSPM------------VAQG--TQTPHRPSTPRLVWQES 1550
            +  T SP P S   R+ G   P P+            VA+G  T+ P R +      +++
Sbjct: 106  AKNT-SPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164

Query: 1551 SQEAPFMVITLASDASSQTRMVHASASTSPLCSPTET---QPTTHGYSQTTPPSVSQLPP 1607
            S   P       + + +  R   A+ +   L  P  +   +P T G  ++   +      
Sbjct: 165  SGPTP------GTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTT 218

Query: 1608 EPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVD 1667
            EP   P   R PSAG          G L          S+ P +S    GP   GT    
Sbjct: 219  EP--SPAARRRPSAG----------GGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266

Query: 1668 LRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLA 1727
               + +P P  L  Q +    +    +    AL P+      +  PL             
Sbjct: 267  AHPS-QPKPKGL--QALRPPQVTPPRKDAAPALGPL------SSSPLA------------ 305

Query: 1728 TATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVK-QVEQAVQTAPY 1786
                   T + S  +  Q  P +   P+ S L       +P+ LA        ++QT P 
Sbjct: 306  -------TPSPSAALQSQAPPTLPATPHSSSLTCQL--ATPLPLAPPSPSAPPSLQTLP- 355

Query: 1787 RSGPRGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATP 1846
               P   P          P+Q         L        S  L P   P P A P  A P
Sbjct: 356  --SPPATP----------PSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALP 403

Query: 1847 AELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQLACCDMVYK 1906
              L++   P A  P + +          +   L + P          P S         +
Sbjct: 404  -PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-------PPSP------PVQ 449

Query: 1907 LPFGSSCTGTFHPAPSVPEKSMAD-AAPPGQ--SSSPFYGPRDPEPPEPPTYRAQGVVGP 1963
             PF    +    P+ + P ++    AAPP Q   S P   P  P    PP  +A   +  
Sbjct: 450  APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPP--QAPPPLAA 507

Query: 1964 GPHEEQRPYPQGLP 1977
             P +  +P PQ  P
Sbjct: 508  PPLQLAKPPPQAPP 521



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 117/521 (22%), Positives = 159/521 (30%), Gaps = 124/521 (23%)

Query: 1829 LKPGPVPEPGAEPHRATPAELRSHALPGA--RKPHTVVVQMGEGTAGTVTTLLPEEPAGA 1886
            L P P   P   P   TPA LR     GA  RKP      + E   G     +PE    A
Sbjct: 25   LTPRPPGSPRPPPP-VTPAALRVLGAAGAVGRKP------LAERAGGIGGATIPESAPRA 77

Query: 1887 LDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRD 1946
                                 P  S+ T + +PA   P     + APP +++SP      
Sbjct: 78   G--------------------PTRSAGTSSRNPASRPPASGRGERAPPAKNTSP------ 111

Query: 1947 PEPPEPPTYRAQGVVGPGPHEEQRPYPQGLPGRLYSSMSDTNLAEAGLNYHAQRI---GQ 2003
               P     RA G   PGP                       L + GL   A+     G+
Sbjct: 112  --GPVSSPGRASGTTRPGP-----------------------LGQKGLRISAEETVARGK 146

Query: 2004 LFQGPGRDSAMDLSSLKHSYSLGFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSS 2063
              + P R +                        L  G+  D   PT     P   RR  +
Sbjct: 147  ATEAPKRSA------------------------LSAGARRDTSGPTPGTPSPAMARRSRA 182

Query: 2064 VSNIYSDHRYGPRGDAVGFQEASLAQYSATTAREISRMCAALNSMDQYGGRHGSGGGGPD 2123
                    R  P        E      S+ +    +    A         R  S GGG  
Sbjct: 183  AGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAAR-------RRPSAGGG-- 233

Query: 2124 LVQYQPQHGPGLSAPQSLVPLR--PGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLL 2181
             +Q         SA     P R  P   G P  P  HPS     Q  P   Q     Q+ 
Sbjct: 234  -LQRPASRSLSSSATPLSSPARSGPSARGTPRAP-AHPS-----QPKPKGLQALRPPQVT 286

Query: 2182 PSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSL 2241
            P       A G + S+   P+A     T  P++ L+      +     S  +T    T L
Sbjct: 287  PPRKDAAPALGPLSSS---PLA-----TPSPSAALQSQAPPTLPATPHSSSLTCQLATPL 338

Query: 2242 TRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEM 2301
                 +AP  P  P  L   P+P       + PP++    LG P   +A  +  PS P  
Sbjct: 339  P----LAPPSPSAPPSLQTLPSPP------ATPPSQATTSLGSP-TLQATHSFLPSPPLS 387

Query: 2302 PVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
            P+     +  P      ++     PA  PL+    P+  AP
Sbjct: 388  PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 77/299 (25%), Positives = 99/299 (33%), Gaps = 32/299 (10%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQ-PPAPQYS------AGSGGPTQNGFPAH--QAPTYPGP 3086
            P +  A   P  P A   P  Q PP+P  S      A       N    H  QAP  P P
Sbjct: 385  PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 444

Query: 3087 STYPAPAFPPGASYPAEP-GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKP 3145
            S      F P AS P  P   P  QA  P    A    +P +     P+   +  P Q P
Sbjct: 445  SPPVQAPFSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 502

Query: 3146 RQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGS 3205
               +   L+   P      A    P+ + PS      P  S     G+ P  P A    S
Sbjct: 503  PPLAAPPLQLAKPPPQAPPALATPPLQALPS------PPASF---PGQAPFSPSASLPMS 553

Query: 3206 VSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEP-----LGPG 3260
               +P P  P       L+  VP +      +    +  T   PD+    P     L PG
Sbjct: 554  PLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPT-PGPDTSVSGPRLTLALAPG 610

Query: 3261 SSGRPGKEPGEPGVLDGPTLPCCYARGEEESEE-DSYDPRGKGGHLRSMESNGRPASTH 3318
                P + P     L GP L    +      EE   YD   +GG   S   +   A+ H
Sbjct: 611  PPPPPSRSPS--STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 667



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 106/470 (22%), Positives = 144/470 (30%), Gaps = 80/470 (17%)

Query: 3446 PSAYSGEKLSSHDFSGWGKGYEREREAV----ERLQKAGPKPSSLSMAHSRVRPPMRSQA 3501
            P    G ++S+ +    GK  E  + +      R   +GP P + S A +R     RS+A
Sbjct: 128  PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-----RSRA 182

Query: 3502 SEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYIL 3561
            +  E     L RP P+  P PP                      +GPR       E    
Sbjct: 183  AGTEVG---LPRPAPSARPRPP---------------------TEGPRKSVSSASE---- 214

Query: 3562 DDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYD 3621
               H     S A            +P                 S    RG  R   H   
Sbjct: 215  ---HSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQ 271

Query: 3622 EPPE--EGLWPHDEGGPGRHASAKEHRHGDHG----RHSGRHTGEEPGRRAAKPHARDLG 3675
              P+  + L P     P + A+                S     + P    A PH+  L 
Sbjct: 272  PKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPTLPATPHSSSLT 331

Query: 3676 RHEARPHSQPSSAPAMPKKGQ--PGYPSSAEYSQPSRASSAYHHASDSKKGSRQ-AHSGP 3732
               A P      +P+ P   Q  P  P++     PS+A+++    S + + +     S P
Sbjct: 332  CQLATPLPLAPPSPSAPPSLQTLPSPPATP----PSQATTSL--GSPTLQATHSFLPSPP 385

Query: 3733 AALQSKAEPQAQPQLQ--GRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPP 3790
             +  +   PQA P L     QA P P  S   S    PS  A         Q      PP
Sbjct: 386  LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS--PP 443

Query: 3791 QQALTQARLQQQSQPTTRGSAPAASQ---------------PAGKPQPGPSTATGPQPAG 3835
                 QA     + P    SA   SQ               P   P   PS    PQ   
Sbjct: 444  PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503

Query: 3836 PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
            P  A     +K   +AP     P  Q  P P PA       PG  P +P+
Sbjct: 504  PLAAPPLQLAKPPPQAPPALATPPLQALPSP-PASF-----PGQAPFSPS 547



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 41/130 (31%), Positives = 54/130 (41%), Gaps = 15/130 (11%)

Query: 3769 SGAASRQPQTQQQQQGL------GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQ 3822
            +GAA+R P  +    GL      G   P   +T A L+        G  P A +  G   
Sbjct: 10   AGAAARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-- 65

Query: 3823 PGPSTATGPQP-AGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT- 3880
             G +T     P AGP R+  T+     ++ P  GR  +A PA    P  V +  R  GT 
Sbjct: 66   -GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTT 124

Query: 3881 -PGAPAGQPG 3889
             PG P GQ G
Sbjct: 125  RPG-PLGQKG 133



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 39/122 (31%), Positives = 49/122 (40%), Gaps = 9/122 (7%)

Query: 2235 AVPLTSLTRVP-MIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGA 2293
            A   T   R P ++ PR P  P      P P   P A  V  A G V   KP A +A G 
Sbjct: 12   AAARTPAARAPGLLTPRPPGSPR-----PPPPVTPAALRVLGAAGAVGR-KPLAERAGGI 65

Query: 2294 GGPSRPEMP--VGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSR 2351
            GG + PE     G  R     +  PA+   A+G    AP A    P   +  G +   +R
Sbjct: 66   GGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 125

Query: 2352 PG 2353
            PG
Sbjct: 126  PG 127



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 107/480 (22%), Positives = 156/480 (32%), Gaps = 96/480 (20%)

Query: 1499 RATAEFSTQTPSP-APASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFM 1557
            +A A  + +TP+  AP    PR PG+P P P           P TP          A   
Sbjct: 7    KAKAGAAARTPAARAPGLLTPRPPGSPRPPP-----------PVTP----------AALR 45

Query: 1558 VITLASDASSQTRMVHASA-------STSPLCSPTETQPTTHGYSQTTPPSV---SQLPP 1607
            V+  A     +     A          ++P   PT +  T+     + PP+     + PP
Sbjct: 46   VLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPP 105

Query: 1608 ---EPPGPPGFP-RVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGT 1663
                 PGP   P R       GPL   G      E ++  + +  P  S +  G R    
Sbjct: 106  AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGAR---- 161

Query: 1664 AVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALD-PIPGRQSTAVQPLVINLNAQE 1722
                 R    PTP      G    ++A  +R  G  +  P P   +    P         
Sbjct: 162  -----RDTSGPTP------GTPSPAMARRSRAAGTEVGLPRPAPSARPRPP-----TEGP 205

Query: 1723 HTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQ 1782
               +++A+  S T  S    A +++P               GGG     ++         
Sbjct: 206  RKSVSSASEHSTTEPSP---AARRRP-------------SAGGGLQRPASRSLSSSATPL 249

Query: 1783 TAPYRSGP--RGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIG---LKPGPVPEP 1837
            ++P RSGP  RG PR         P  +  L    V   +   A ++G     P   P P
Sbjct: 250  SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 1838 GAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPESQ 1897
             A      P       LP      ++  Q+      T   L P  P+    L  +   S 
Sbjct: 310  SAALQSQAPP-----TLPATPHSSSLTCQL-----ATPLPLAPPSPSAPPSLQTL--PSP 357

Query: 1898 LACCDMVYKLPFGS---SCTGTFHPAPSV-PEKSMADAAPPGQSSSPFYGPRDPEPPEPP 1953
             A          GS     T +F P+P + P  +    APP  +  P   P  P PP  P
Sbjct: 358  PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAP--PSPPASP 415



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 47/183 (25%), Positives = 66/183 (36%), Gaps = 29/183 (15%)

Query: 3041 APATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQA-----PTYP-GPSTYPAPAF 3094
            AP +PS P + Q      P+P  +  S   T  G P  QA     P+ P  P   P P  
Sbjct: 341  APPSPSAPPSLQTL----PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQA 396

Query: 3095 PPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLE 3154
            PP  + P     P+  A  P    A  +P       +  + A    P   P Q   +   
Sbjct: 397  PPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS--- 453

Query: 3155 QKVPTNYEVIASPVVPMSSAPSET--SYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAP 3212
                      + PV P ++ PS+   S + P +       +VP  P A    S S +P P
Sbjct: 454  -------PPASPPVSPSATPPSQAPPSLAAPPL-------QVPPSPPASPPMSPSATPPP 499

Query: 3213 TYP 3215
              P
Sbjct: 500  QAP 502



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 53/236 (22%), Positives = 79/236 (33%), Gaps = 19/236 (8%)

Query: 526 GEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK 585
           G P P PP T     V     A G  PL ++   G+G     +P  A       S   S 
Sbjct: 31  GSPRPPPPVTPAALRVLGAAGAVGRKPLAERAG-GIG--GATIPESAPRAGPTRSAGTSS 87

Query: 586 ASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
            +P ++P  +    + P +         T   P+  P   +  T   P  + G+R +   
Sbjct: 88  RNPASRPPASGRGERAPPAKN-------TSPGPVSSPGRASGTTRPGPLGQKGLRISAEE 140

Query: 646 TPVVKAVPEAPK-----GGEAEDLVGK----PYSQDASRSPQSLSDTGYSSDGISSSQSE 696
           T       EAPK      G   D  G     P    A RS  + ++ G      S+    
Sbjct: 141 TVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRP 200

Query: 697 ITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSG 752
            T   ++ V        T P P +       G   RP  ++   + +  S P  SG
Sbjct: 201 PTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSG 256



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 55/207 (26%), Positives = 74/207 (35%), Gaps = 18/207 (8%)

Query: 2142 VPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTP 2201
            +PL P     P   +  PSP       PA     A   L   + T++A    + S   +P
Sbjct: 338  LPLAPPSPSAPPSLQTLPSP-------PATPPSQATTSL--GSPTLQATHSFLPSPPLSP 388

Query: 2202 IAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV---PLGPTGL 2258
            +A T P    PA  L P+       P AS  ++ +   S      +A  +   P  P   
Sbjct: 389  LA-TPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPS 445

Query: 2259 YRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTP-- 2316
                AP   P +  V P+  P     P+ A  P    PS P  P  +    P P   P  
Sbjct: 446  PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL 505

Query: 2317 -AAIKEAAGAPAPAPLAGQKPPADAAP 2342
             A   + A  P  AP A   PP  A P
Sbjct: 506  AAPPLQLAKPPPQAPPALATPPLQALP 532



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 69/245 (28%), Positives = 83/245 (33%), Gaps = 49/245 (20%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA--LQSK 3738
            P   P +    P +  P  P+S     P   S++    S       QA    AA  LQ  
Sbjct: 516  PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP-MSPLATPPPQAPPVLAAPLLQVP 574

Query: 3739 AEPQAQPQLQG--RQAAPGPQQSQS--------------PSSRQIPS--------GAASR 3774
              P A P LQ   R   PGP  S S              P SR   S        G +S 
Sbjct: 575  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634

Query: 3775 QPQTQQQ--------QQGLGLQPPQQALTQARLQQQSQPTTRGSAP--AASQPAGKPQPG 3824
               T ++        + G    PP  A   A         +RG AP  A     G P P 
Sbjct: 635  ATSTPEELRGYDSGPEGGAAASPPPDAELAAC---HPAAWSRGPAPPLAFRGAPGAPLPW 691

Query: 3825 PSTATGPQPA-GPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGA 3883
            P  ATGP  A G     +T G +    AP         P P PG +G KA A  G   GA
Sbjct: 692  PP-ATGPGSADGLCTIYETEGPESATPAPGA-----LDPGPSPGTSGGKAAA--GAGAGA 743

Query: 3884 PAGQP 3888
             +  P
Sbjct: 744  SSRSP 748



 Score = 34.7 bits (78), Expect = 1.9
 Identities = 47/166 (28%), Positives = 60/166 (36%), Gaps = 24/166 (14%)

Query: 3024 GCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTY 3083
            G   PA + +   AT  +    SGP+A    R  P AP   A    P   G  A + P  
Sbjct: 233  GLQRPASRSLSSSATPLSSPARSGPSA----RGTPRAP---AHPSQPKPKGLQALRPPQV 285

Query: 3084 PGPSTYPAPAFPPGASYP-AEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPL 3142
              P    APA  P +S P A P         P+     Q P PT  +T    P  S    
Sbjct: 286  TPPRKDAAPALGPLSSSPLATPS--------PSAALQSQAP-PTLPAT----PHSSSLTC 332

Query: 3143 QKPRQTSLADLEQKVPTNYEVIAS-PVVPMSSAPSETSYSGPAVSS 3187
            Q      LA      P + + + S P  P S A   TS   P + +
Sbjct: 333  QLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA--TTSLGSPTLQA 376



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 68/255 (26%), Positives = 88/255 (34%), Gaps = 40/255 (15%)

Query: 2129 PQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPG-NLAQYGP----AAGQGTAVRQLLPS 2183
            PQ  P L+AP   VP  P        P   P+PG + +  GP    A   G         
Sbjct: 560  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 619

Query: 2184 TATVRAAD--GMIYSTINTP-------------IAATLPITTQPASVLRPMVRGGMYRPY 2228
            ++T+   D  G   S  +TP              AA+ P   + A+        G   P 
Sbjct: 620  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 679

Query: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAP-SRFPIASSVPPAEGPVYLGKPAA 2287
            A  G    P   L   P   P    G   +Y    P S  P   ++ P   P   G  AA
Sbjct: 680  AFRGAPGAP---LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 736

Query: 2288 AKAPGAGGPSRP-------EMPVGAAREEPLP-----TTTPAAIKEAAGAPAPAPLAGQK 2335
            A A GAG  SR        E+P+GA +   +      T   AA + AAG     P   + 
Sbjct: 737  AGA-GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE- 794

Query: 2336 PPADAAPGGGSGALS 2350
                   GG   ALS
Sbjct: 795  --GGGVTGGARAALS 807



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 83/345 (24%), Positives = 116/345 (33%), Gaps = 63/345 (18%)

Query: 2619 SAEWEQPVRRRRSRLPRHSDSGSDSKHDA------TASSSSAAATVRAMSSVGIQTISDC 2672
            SAE E   R + +  P+ S   + ++ D       T S + A  +  A + VG+   +  
Sbjct: 137  SAE-ETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPS 195

Query: 2673 SVQTEPDQLPRVS-PAIHITAATDPKVEIVRYISAPEKTGRGESLACQTEPDGQAQGVAG 2731
            +    P + PR S  +    + T+P     R  SA    G G            A  ++ 
Sbjct: 196  ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA----GGGLQRPASRSLSSSATPLSS 251

Query: 2732 PQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPD--PLEIGYQAHLPPESLSQLVSRQPPK 2789
            P   GP+A            P P G    + P   P        L P S S L +  P  
Sbjct: 252  PARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSA 311

Query: 2790 SPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSALRQQTLPRPMKT---- 2845
            + Q    P  P +PH       +SS     A   P    +  +    QTLP P  T    
Sbjct: 312  ALQSQAPPTLPATPH-------SSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364

Query: 2846 LQRSLSDPK-----------PLSPTAEESAKERFSLYQHQGGLGSQVSALPPNSLVRKVK 2894
               SL  P            PLSP A    +   +L            ALPP        
Sbjct: 365  ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPAL------------ALPP-------- 404

Query: 2895 RTLPSPPPEEAHLPLAGQA-----SPQLYAASLLQRGLTGPTTVP 2934
              L +PP   A  PL+  A     +P   A  LLQ   + P + P
Sbjct: 405  --LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 447



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 62/218 (28%), Positives = 76/218 (34%), Gaps = 47/218 (21%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQ--PSRASSAYHHASDSKKGSRQAHSGPAALQSK 3738
            P S P  AP  P    P  PS+   SQ  PS A      A   +       S P +  + 
Sbjct: 443  PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLA------APPLQVPPSPPASPPMSPSAT 496

Query: 3739 AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQAR 3798
              PQA P L    AAP  Q ++ P   Q P   A+               PP QAL    
Sbjct: 497  PPPQAPPPL----AAPPLQLAKPPP--QAPPALAT---------------PPLQALPSP- 534

Query: 3799 LQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP-RAEQTNGSKGTAKAPQQGRA 3857
                S P     +P+AS P        S    P P  PP  A        +  A    +A
Sbjct: 535  --PASFPGQAPFSPSASLPM-------SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA 585

Query: 3858 PQAQPAPGP-----GPAGVKAGARPGGTPGAPAGQPGA 3890
            P+  P PGP     GP    A A   G P  P+  P +
Sbjct: 586  PRRPPTPGPDTSVSGPRLTLALA--PGPPPPPSRSPSS 621



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 61/234 (26%), Positives = 82/234 (35%), Gaps = 23/234 (9%)

Query: 2129 PQHGPGLSAPQSL--VPLRPGL--------LGNPTFPEGH---PSP--GNLAQYGPAAGQ 2173
            P   P  SAP SL  +P  P          LG+PT    H   PSP    LA   P A  
Sbjct: 339  PLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 398

Query: 2174 GTAVRQLL--PSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASG 2231
              A+  L   PS         +   +   P A  + +   P S          + P AS 
Sbjct: 399  ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 458

Query: 2232 GITAVPLTSLTRVPMIA-PRVPLGPTGLYRYP-APSRFPIASSVPP-AEGPVYLGKPAAA 2288
             ++          P +A P + + P+     P +PS  P   + PP A  P+ L KP   
Sbjct: 459  PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 518

Query: 2289 KAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
              P    P    +P   A        +P+A    +    P P   Q PP  AAP
Sbjct: 519  APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP---QAPPVLAAP 569



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 31/88 (35%), Positives = 37/88 (42%), Gaps = 13/88 (14%)

Query: 3812 PAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGV 3871
            PAA  P G   P P  +  P P   P A +  G+ G       GR P A+ A G G A +
Sbjct: 17   PAARAP-GLLTPRPPGSPRPPPPVTPAALRVLGAAGAV-----GRKPLAERAGGIGGATI 70

Query: 3872 KAGA-RPGGTPGA------PAGQPGADG 3892
               A R G T  A      PA +P A G
Sbjct: 71   PESAPRAGPTRSAGTSSRNPASRPPASG 98


>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
          Length = 1970

 Score = 81.6 bits (200), Expect = 1e-14
 Identities = 98/345 (28%), Positives = 140/345 (40%), Gaps = 51/345 (14%)

Query: 1300 PMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS 1359
            P   N  P +P  SPT  +   S ++P+ S +S     P    T      T       S 
Sbjct: 1631 PTSPNYSPTSPSYSPT--SPSYSPTSPSYSPTS-----PSYSPTSPSYSPTSPSYSPTSP 1683

Query: 1360 PASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSY 1419
              SP+S S     P S  P +P+ +  +P  +     Y +P SP+ S  SPS S T+ SY
Sbjct: 1684 SYSPTSPSYSPTSP-SYSPTSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPTSPSY 1741

Query: 1420 GHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPP 1479
              SPT+ NY       P +P+    +   +   P  +      TP        ++ +SP 
Sbjct: 1742 --SPTSPNYS------PTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPN----YSPTSPS 1789

Query: 1480 LSPSSPSESPT---FSPGKMGPRATAEFSTQTPS-----PAPASDMPRSPG----APTPS 1527
             SP+SPS SPT   +SP    PR T +  T TPS     P+  S  P SP     +P+ S
Sbjct: 1790 YSPTSPSYSPTSPSYSPSS--PRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYS 1847

Query: 1528 PMVAQGTQTP---------HRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASAS- 1577
            P   + T T          + P++P+      +        +  S   S T  V+   S 
Sbjct: 1848 PSSPEYTPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSP 1907

Query: 1578 ----TSPLCSPTETQ--PTTHGYSQTTPPSVSQLPPEPPGPPGFP 1616
                TSP  SPT  +  PT+  YS T+P   +  P  P   P  P
Sbjct: 1908 KYSPTSPTYSPTSPKYSPTSPTYSPTSPKGSTYSPTSPGYSPTSP 1952



 Score = 79.7 bits (195), Expect = 5e-14
 Identities = 92/336 (27%), Positives = 139/336 (41%), Gaps = 26/336 (7%)

Query: 1305 GGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPA-SP 1363
            G P +PG S   + +P    +P+ S +S     P            Q P    +SP+ SP
Sbjct: 1570 GSPGSPGPSSPYIPSPGGAMSPSYSPTS-----PAYEPRSPGGYTPQSPSYSPTSPSYSP 1624

Query: 1364 SSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSP 1423
            +S S     P +  P +P+ +  +P  +     Y +P SP+ S  SPS S T+ SY  SP
Sbjct: 1625 TSPSYSPTSP-NYSPTSPSYSPTSPSYSPTSPSY-SPTSPSYSPTSPSYSPTSPSY--SP 1680

Query: 1424 TTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPS 1483
            T+ +Y   +     +P+  + +  +    P S S     +P  S     ++ +SP  SP+
Sbjct: 1681 TSPSYSPTSPSY--SPTSPSYSPTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPT 1737

Query: 1484 SPSESPT---FSPGKMGPRATA-EFSTQTPSPAPASD--MPRSPGAPTPSPMVA------ 1531
            SPS SPT   +SP       T+  +S  +PS +P S    P SP     SP  +      
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSY 1797

Query: 1532 QGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTT 1591
              T   + PS+PR   Q  +        + +S + S T   +   S S   S  E  PT+
Sbjct: 1798 SPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTPTS 1857

Query: 1592 HGYSQTTPPSVSQLPPEPPGPPGF-PRVPSAGADGP 1626
              YS T+P      P   P  P + P  P      P
Sbjct: 1858 PKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSP 1893



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 78/271 (28%), Positives = 109/271 (40%), Gaps = 28/271 (10%)

Query: 1375 SQGPG-TPATTAVAPCPAGLPRGYMTPASPAGSER-----SPSPSST-------AHSYGH 1421
            S G G TP     +P  A    G+    SPA S       SP PSS        A S  +
Sbjct: 1534 SVGSGMTPGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSY 1593

Query: 1422 SPTTANYGSQTED--LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPP 1479
            SPT+  Y  ++     PQ+PS    +   +   P  +      +P  S +YS  + S  P
Sbjct: 1594 SPTSPAYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSP-TSPSYSPTSPSYSP 1652

Query: 1480 LSPSSPSESPTFSPGKMGPRATA-EFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPH 1538
             SPS    SP++SP       T+  +S  +PS +P S    SP +P+ SP     T   +
Sbjct: 1653 TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP-SYSPTSPSYSP-----TSPSY 1706

Query: 1539 RPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQ--PTTHGYSQ 1596
             P++P       S        +  S + S T   +  + TSP  SPT     PT+  YS 
Sbjct: 1707 SPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY--SPTSPNYSPTSPNYTPTSPSYSP 1764

Query: 1597 TTPPSVSQLPPEPPGPPGF-PRVPSAGADGP 1626
            T+P      P   P  P + P  PS     P
Sbjct: 1765 TSPSYSPTSPNYTPTSPNYSPTSPSYSPTSP 1795



 Score = 62.8 bits (151), Expect = 7e-09
 Identities = 73/243 (30%), Positives = 102/243 (41%), Gaps = 35/243 (14%)

Query: 1405 GSERSP----SPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGE 1460
            GS  SP    SP+ T  + G +P    YG+ +   P   SG+     AA   P +ASD  
Sbjct: 1504 GSAPSPMGGISPAMTPWNQGATPA---YGAWS---PSVGSGMTPG--AAGFSPSAASDAS 1555

Query: 1461 GGTPQPSRAYSYFASSSPPLSPSSP-------SESPTFSPGKMG--PRATAEFSTQTPSP 1511
            G +P  S A+S    S     PSSP       + SP++SP      PR+   ++ Q+PS 
Sbjct: 1556 GFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSY 1615

Query: 1512 APASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRM 1571
            +P S    SP +P+ SP     T   + P++P       S        +  S + S T  
Sbjct: 1616 SPTSP-SYSPTSPSYSP-----TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1669

Query: 1572 VHASAS-----TSPLCSPTET--QPTTHGYSQTTPPSVSQLPPEPPGPPGF-PRVPSAGA 1623
             ++  S     TSP  SPT     PT+  YS T+P      P   P  P + P  PS   
Sbjct: 1670 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1729

Query: 1624 DGP 1626
              P
Sbjct: 1730 TSP 1732



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 66/233 (28%), Positives = 86/233 (36%), Gaps = 49/233 (21%)

Query: 1300 PMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSS 1359
            P   N  P +P  SPT   +P    T  S   S  R  P            Q P    SS
Sbjct: 1778 PTSPNYSPTSPSYSPT---SPSYSPTSPSYSPSSPRYTP------------QSPTYTPSS 1822

Query: 1360 PA-SPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHS 1418
            P+ SPSS S          P +P  T  +P  +     Y TP SP  S  SP  S T+  
Sbjct: 1823 PSYSPSSPS--------YSPTSPKYTPTSPSYSPSSPEY-TPTSPKYSPTSPKYSPTSPK 1873

Query: 1419 YGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP 1478
            Y  SPT+  Y   T     +P+    +  +    P S        P+ S     ++ +SP
Sbjct: 1874 Y--SPTSPTYSPTTPKY--SPTSPTYSPTSPVYTPTS--------PKYSPTSPTYSPTSP 1921

Query: 1479 PLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVA 1531
              SP+SP+ SPT   G             T SP      P SP     SP ++
Sbjct: 1922 KYSPTSPTYSPTSPKG------------STYSPTSPGYSPTSPTYSLTSPAIS 1962



 Score = 50.1 bits (118), Expect = 4e-05
 Identities = 95/429 (22%), Positives = 134/429 (31%), Gaps = 71/429 (16%)

Query: 233  APRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQ 292
            +P + S     SP  SPA SP     G P       P  P PG   + +   TS      
Sbjct: 1547 SPSAASDASGFSPGYSPAWSPTP---GSPGSPGPSSPYIPSPGGAMSPSYSPTS-----P 1598

Query: 293  AAAPPEVGRVSPQPPQ--PTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKL 350
            A  P   G  +PQ P   PT PS +   P         +   P+                
Sbjct: 1599 AYEPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPS---------------- 1642

Query: 351  FGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAP 410
                      + T  S  P + +    +PS       ++  S    P    + P   P  
Sbjct: 1643 ---------YSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP----TSPSYSPTS 1689

Query: 411  GAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQA 470
             + +       P S P   P     TSP +       +  + +   T P      P    
Sbjct: 1690 PSYSPTSPSYSPTS-PSYSP-----TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP---- 1739

Query: 471  ELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTP 530
                 S SP + N   T          ++PT      T               +    +P
Sbjct: 1740 -----SYSPTSPNYSPTSPNYTPTSPSYSPTSPSYSPTS---------PNYTPTSPNYSP 1785

Query: 531  LPPPTSQQPPVGAPHRASGTSPLKQKGPQG-LGQPSGPLPAKASPLSTKASPLPSKASPQ 589
              P  S   P  +P   S +    +  PQ     PS P  + +SP  +  SP  +  SP 
Sbjct: 1786 TSPSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPS 1845

Query: 590  AKPLRASEPSKTPSSVQEKKTRVPTKAEPMPK-PPPETTPTPATPKVKSGVRRAEPATPV 648
              P   S P  TP+S +   T  P  +   PK  P   T +P TPK         P +PV
Sbjct: 1846 YSP---SSPEYTPTSPKYSPTS-PKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPV 1901

Query: 649  VKAVPEAPK 657
                P +PK
Sbjct: 1902 Y--TPTSPK 1908



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 76/358 (21%), Positives = 114/358 (31%), Gaps = 51/358 (14%)

Query: 12   GDGPLPPGGAGPGPGP------------GPGPGAGKPPSAPAGGGQLPAAGAARSTAVPP 59
            G  P P GG  P   P             P  G+G  P A        +  +  S    P
Sbjct: 1504 GSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSP 1563

Query: 60   VPGPGPGPGPGPGPGS----------------TSRRLDPKEPLG---NQRAASPTPKQAS 100
               P PG    PGP S                TS   +P+ P G      + SPT    S
Sbjct: 1564 AWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTSPSYS 1623

Query: 101  ATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGS-TPTSP-YSV 158
             T+P + SP  T         +  P       +    S  SPS SP   S +PTSP YS 
Sbjct: 1624 PTSPSY-SP--TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP 1680

Query: 159  PQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCL 218
               +  P+S   P    +  + +P+ P+++  +  ++            +      +   
Sbjct: 1681 TSPSYSPTS---PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1737

Query: 219  NCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQ 278
            +            T+P        +SP  SP++SP            +  P  P      
Sbjct: 1738 SPSYSPTSPNYSPTSPNYTPTSPSYSPT-SPSYSPTSP---------NYTPTSPNYSPTS 1787

Query: 279  AETARATSVPGPAQAAAPPEVGRVSPQPP--QPTKPSTAEPRPPAGEAPAKSATAVPA 334
               +  +    P   +  P   R +PQ P   P+ PS +   P       K     P+
Sbjct: 1788 PSYSPTSPSYSPTSPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPS 1845



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 58/238 (24%), Positives = 82/238 (34%), Gaps = 31/238 (13%)

Query: 3039 AAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGA 3098
            A  P +P G T  Q P + P +P YS  S  P+ +    + +PT P  S       P   
Sbjct: 1599 AYEPRSPGGYTP-QSPSYSPTSPSYSPTS--PSYSPTSPNYSPTSPSYSPTSPSYSPTSP 1655

Query: 3099 SY-PAEPGL-PNQQAFRPTG-HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQ 3155
            SY P  P   P   ++ PT   Y+  +P  +  S  +   + S +P              
Sbjct: 1656 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP----------- 1704

Query: 3156 KVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYP 3215
                +Y   +    P S + S TS S    S  Y        P + +    S +  PT P
Sbjct: 1705 ----SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP 1760

Query: 3216 SDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKEPGEP 3272
            S S  +        NY         T  S + +P S    P  P  S   P   P  P
Sbjct: 1761 SYSPTSPSYSPTSPNY---------TPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSP 1809



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 69/284 (24%), Positives = 91/284 (32%), Gaps = 43/284 (15%)

Query: 3024 GCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSA-----GSG-GPTQNGFPA 3077
            G   P G F       +AP+   G +    P  Q   P Y A     GSG  P   GF  
Sbjct: 1494 GAAGPTGMFF-----GSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSP 1548

Query: 3078 HQAPTYPGPSTYPAPAFPPGASYPAEPG-----------------LPNQQAFRP--TGHY 3118
              A    G S   +PA+ P    P  PG                  P   A+ P   G Y
Sbjct: 1549 SAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGY 1608

Query: 3119 AGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSET 3178
              Q+P  +  S  +   + S +P   P  +  +        +Y   +    P S + S T
Sbjct: 1609 TPQSPSYSPTSPSYSPTSPSYSP-TSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPT 1667

Query: 3179 SYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDIS 3238
            S S    S  Y        P +      S S +PT PS S  +        +Y       
Sbjct: 1668 SPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY------- 1720

Query: 3239 ELTKDSTSTAPDSQRLEPLGPG-SSGRPGKEPGEPGVLDGPTLP 3281
              +  S S +P S    P  P  S   P   P  P     PT P
Sbjct: 1721 --SPTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYT--PTSP 1760



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 56/229 (24%), Positives = 81/229 (35%), Gaps = 19/229 (8%)

Query: 3060 APQYS-AGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPP--GASYPAEPG--LPNQQAFRP 3114
            +P YS A S  P   G P   +P  P P    +P++ P   A  P  PG   P   ++ P
Sbjct: 1558 SPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSP 1617

Query: 3115 TG-HYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSS 3173
            T   Y+  +P  +  S  +   + S +P   P  +  +        +Y   +    P S 
Sbjct: 1618 TSPSYSPTSPSYSPTSPNYSPTSPSYSP-TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1676

Query: 3174 APSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVM 3233
            + S TS S    S  Y        P +      S S +PT PS S  +        +Y  
Sbjct: 1677 SYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY-- 1734

Query: 3234 IDDISELTKDSTSTAPDSQRLEPLGPG-SSGRPGKEPGEPGVLDGPTLP 3281
                   +  S S +P S    P  P  +   P   P  P     PT P
Sbjct: 1735 -------SPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSY--SPTSP 1774



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 84/390 (21%), Positives = 134/390 (34%), Gaps = 34/390 (8%)

Query: 246  ALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQ-AETARATSVPGPAQAAAPPEVGRVSP 304
            A+SP++SP   P  +P     R PGG  P S   + T+ + S   P+ +   P     SP
Sbjct: 1588 AMSPSYSPTS-PAYEP-----RSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSP 1641

Query: 305  QPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTL 364
                PT PS + P  P+    + S +        T  +    +        S    + T 
Sbjct: 1642 SY-SPTSPSYS-PTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPSY---SPTS 1696

Query: 365  MSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGS 424
             S  P + +    +PS       ++  S    P    + P   P   + +       P S
Sbjct: 1697 PSYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSP----TSPSYSPTSPSYSPTSPNYSPTS 1752

Query: 425  GPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG-SKSPANYN 483
             P   P T  + SP        + +     P   P   +  P   +      S SP++  
Sbjct: 1753 -PNYTP-TSPSYSPTSPSYSPTSPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYSPSSPR 1810

Query: 484  TCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGA 543
                      +   ++P+      T        T      S  E TP  P  S   P  +
Sbjct: 1811 YTPQSPTYTPSSPSYSPSSPSYSPTS--PKYTPTSPSYSPSSPEYTPTSPKYSPTSPKYS 1868

Query: 544  PHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPS 603
            P     TSP K         P+ P  +  SP  +  SP+ +  SP+  P   + P+ +P+
Sbjct: 1869 P-----TSP-KYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSP---TSPTYSPT 1919

Query: 604  SVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
            S +      PT     P  P  +T +P +P
Sbjct: 1920 SPKYS----PTSPTYSPTSPKGSTYSPTSP 1945


>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
          Length = 841

 Score = 81.3 bits (199), Expect = 2e-14
 Identities = 88/322 (27%), Positives = 139/322 (43%), Gaps = 33/322 (10%)

Query: 2201 PIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYR 2260
            P +    ++   AS L P  +     P  S    A P  S      + P+ P  P G   
Sbjct: 444  PASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPP-SPRGTTA 502

Query: 2261 YPAPS--RFPIASSVPPAEGPVYLG---------KPAAAKAPGAGGPSRPEMPVGAAREE 2309
             P     R   A   P A GP             K +AA A  A  P+    P    +E+
Sbjct: 503  SPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQ 562

Query: 2310 P-LPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQ 2368
            P   T T AA+  +  APAP P+   KP A       +  L     EK   ++E+R+R++
Sbjct: 563  PPAETPTDAAVLTSPPAPAP-PVTPSKPMAGTTDREEATRLLA---EKRRQAREQREREE 618

Query: 2369 QEQLLQLERER----VELEKLRQLRLQEELERERVELQRHRE------EEQLLVQRELQE 2418
            QE+ LQ ER++     +L +  + R + E E  R E Q  RE      EEQ  +Q++ +E
Sbjct: 619  QERRLQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEE 678

Query: 2419 LQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFP 2478
             +       ++Q+ ER+  F  Q ++  ++R +LE+I  +++  + ++ E KQ+Q +   
Sbjct: 679  AEARSREEAERQRLEREKHFQQQEQERQERRKRLEEI--MKRTRKSEVSETKQKQDS--- 733

Query: 2479 AACEAPGRGP-PLAAAELAQNG 2499
                A G  P P+ A E    G
Sbjct: 734  KEANANGSSPEPVKAVEARSPG 755



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 153/712 (21%), Positives = 249/712 (34%), Gaps = 119/712 (16%)

Query: 857  LEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAE 916
            +E    A  G G       +  P PRP P  +P+  P    P +A     +  P+   A 
Sbjct: 1    MESGPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPP---PMSALV--PDTPPDTPPAM 55

Query: 917  ATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSR 976
                S          K + L      G       GP P+  +E     E+ +  P   + 
Sbjct: 56   KNATSS---------KQLPLEPESPSGQV-----GPRPAPPQEESPSSEAKSRGPTPPAM 101

Query: 977  GEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPT 1036
            G       A  P  +S  SPT++ +    SDS P++++  +  ++ + A+ R        
Sbjct: 102  GPRD----ARPPRRSSQPSPTAVPA----SDSPPTKQEVKKAGERHKLAKERREERAKYL 153

Query: 1037 IEDSSEEEELREEEELLRE---QEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTP 1093
                +   E  E+ + LRE   QE+ R +E+QR+++  R+         A   R+R K  
Sbjct: 154  AAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKAEQRRA--------ALEERQRQKLE 205

Query: 1094 PSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEY 1153
              N    E A      +  AE+ +        +S + +L   +       SR   S S  
Sbjct: 206  -KNKERYEAAIQRSVKKTWAEIRQ------QRWSWAGALHHSSPGHKTSGSRC--SVSAV 256

Query: 1154 NLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHG 1213
            NLP  +           S+T  +S    +S + +  E      L+       A +R    
Sbjct: 257  NLPKHVDSIINKRLSKSSATLWNSPSRNRSLQLSAWESSIVDRLMTPTLSFLARSR---- 312

Query: 1214 GPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQA 1273
              S  T PR            R+ G+   P    T    GA++                 
Sbjct: 313  --SAVTLPRN----------GRDQGRGCDPGRGPTWGRAGASL----------------- 343

Query: 1274 SSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPG--TSPTQLAAPVSFSTPTSSDS 1331
                   A   + ++   +A +  + P   +  PLTP   T      AP          +
Sbjct: 344  -------ARGPQPDRTHPSA-AVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPN 395

Query: 1332 SGGRVIP--------DVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPAT 1383
            +GG   P         V+  +   KE ++  K  S+ A   S  K   +P S      A+
Sbjct: 396  AGGSPAPVRRRPEASPVQKKEKKDKERENE-KEKSALARERSLKKRQSLPASPRARLSAS 454

Query: 1384 TAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLA 1443
            TA             +  SP    R  SPS++ H       +   G      P +P G  
Sbjct: 455  TA-------------SELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTT 501

Query: 1444 AA--GRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRAT 1501
            A+  GR  R++    S    G    S++    ++     +P+SP+ SP  SP    P+  
Sbjct: 502  ASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQ-K 560

Query: 1502 AEFSTQTPSPAPASDMPRSPGAP-TPSPMVAQGTQTPHRPSTPRLVWQESSQ 1552
             +   +TP+ A     P +P  P TPS  +A    T  R    RL+ ++  Q
Sbjct: 561  EQPPAETPTDAAVLTSPPAPAPPVTPSKPMA---GTTDREEATRLLAEKRRQ 609



 Score = 49.3 bits (116), Expect = 8e-05
 Identities = 87/393 (22%), Positives = 139/393 (35%), Gaps = 78/393 (19%)

Query: 572 ASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPA 631
           ASP +  ++   S+ SP++K    + PS   +S     +  P+       PP   +P   
Sbjct: 445 ASPRARLSASTASELSPKSK----ARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGT 500

Query: 632 TPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGIS 691
           T   K  VRR E A        E+P     ED      SQ   R+         +S   S
Sbjct: 501 TASPKGRVRRKEEA-------KESPSAAGPED-----KSQSKRRASNEKESAAPASPAPS 548

Query: 692 SSQSEITGVVQQE----VEQLDSAGVTGPHPPSPSEI-HKVGSSMRPLLQAQGLAPSERS 746
            + S      Q+E        D+A +T P  P+P     K  +      +A  L   +R 
Sbjct: 549 PAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRR 608

Query: 747 KPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDF 806
           +       EEQ++R   L    +    +E+L    E   +     RRRE+Q+  E +   
Sbjct: 609 QAREQREREEQERR---LQAERDKRMREEQLAREAEARAEREAEARRREEQEAREKAQ-- 663

Query: 807 GSQLRHDYVEDSSEGGLSPLPPQPPARAAELTD------------------------EDF 842
                    E   +  L     +  AR+ E  +                        E+ 
Sbjct: 664 --------AEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEI 715

Query: 843 MRR----QILEMSAEEDNLEEDDTATS----------GRGLAKHGTQKGGPRPRPEPSQE 888
           M+R    ++ E   ++D+ E +   +S            GL K   QK  P P     QE
Sbjct: 716 MKRTRKSEVSETKQKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPIP-----QE 770

Query: 889 PA-ALPKRRLPHNATTGYEELLPEGGSAEATDG 920
           P  +LP + LP +   G + L     +  +T+G
Sbjct: 771 PQWSLPSKELPASLVNGLQPLPAHQENGFSTNG 803



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 59/249 (23%), Positives = 102/249 (40%), Gaps = 46/249 (18%)

Query: 2262 PAPSRFPIASSVP--PAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAI 2319
            P+P   P+++ VP  P + P  +    ++K      P  PE P G     P P    +  
Sbjct: 33   PSPPPPPMSALVPDTPPDTPPAMKNATSSKQL----PLEPESPSGQVGPRPAPPQEESPS 88

Query: 2320 KEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERER 2379
             EA       P  G   P DA P   S   S       ++   +++ K+  +  +L +ER
Sbjct: 89   SEAKSRGPTPPAMG---PRDARPPRRSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKER 145

Query: 2380 VELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFA 2439
             E E+ + L  ++ +  E+       E+ + L +++LQE                     
Sbjct: 146  RE-ERAKYLAAKKAVWLEK------EEKAKALREKQLQE--------------------- 177

Query: 2440 LQREQLAQQRLQLEQIQ-QLQQQLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQN 2498
             +R +L +QRL+ EQ +  L+++ +Q+LE+ K+R +A       A  R      AE+ Q 
Sbjct: 178  -RRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEA-------AIQRSVKKTWAEIRQQ 229

Query: 2499 GQYWPPLTH 2507
               W    H
Sbjct: 230  RWSWAGALH 238



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 69/273 (25%), Positives = 99/273 (36%), Gaps = 41/273 (15%)

Query: 1371 GMPFSQGPG---TPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTAN 1427
            G   ++GP    T  + AV  CP       +TP S   S    +P+             N
Sbjct: 340  GASLARGPQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGER----RKPN 395

Query: 1428 YGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSE 1487
             G     + + P    A+    +EK     + E      +R  S     S P SP +   
Sbjct: 396  AGGSPAPVRRRPE---ASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPASPRARLS 452

Query: 1488 SPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR--- 1544
            + T S  ++ P++ A  S    SP+ +   P SP  P+P P    G   P +P +PR   
Sbjct: 453  ASTAS--ELSPKSKARPS----SPSTSWHRPASP-CPSPGP----GHTLPPKPPSPRGTT 501

Query: 1545 ------LVWQESSQEAPFMVITLASDASSQTRMVH--------ASASTSPLCSPTETQPT 1590
                  +  +E ++E+P        D S   R           AS + SP  SPT   P 
Sbjct: 502  ASPKGRVRRKEEAKESPSAAGP--EDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQ 559

Query: 1591 THGYSQTTPPSVSQL-PPEPPGPPGFPRVPSAG 1622
                   TP   + L  P  P PP  P  P AG
Sbjct: 560  KEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAG 592



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 59/264 (22%), Positives = 99/264 (37%), Gaps = 47/264 (17%)

Query: 3650 HGRHSGRHTGEEPGRRAAKPHA-RDLGRHEARPHSQPSSA-PAMPKKGQPGYPSSAEYSQ 3707
            +GR  GR  G +PGR      A   L R      + PS+A P  P+       S++  + 
Sbjct: 320  NGRDQGR--GCDPGRGPTWGRAGASLARGPQPDRTHPSAAVPVCPRSA-----SASPLTP 372

Query: 3708 PSRASSAYHHASDSKKGSRQA-HSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQ 3766
             S   S +  A   ++G R+  ++G +    +  P+A P +Q ++     ++++   S  
Sbjct: 373  CSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASP-VQKKEKKDKERENEKEKS-- 429

Query: 3767 IPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAAS--QPAGK-PQP 3823
                 A  + ++ +++Q L   P  +       +   +   R S+P+ S  +PA   P P
Sbjct: 430  -----ALARERSLKKRQSLPASPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSP 484

Query: 3824 GPSTATGPQP--------------------------AGPPRAEQTNGSKGTAKAPQQGRA 3857
            GP     P+P                          AGP    Q+       K      +
Sbjct: 485  GPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPAS 544

Query: 3858 PQAQPAPGPGPAGVKAGARPGGTP 3881
            P   PAP P PA  +    P  TP
Sbjct: 545  PAPSPAPSPTPAPPQKEQPPAETP 568



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 102/515 (19%), Positives = 180/515 (34%), Gaps = 71/515 (13%)

Query: 532  PPPTSQQPPVGAP--HRASGTSPLKQKGPQGLGQ------PSGPLPAKASPLSTKASPLP 583
            P P    P    P   R++  SPL    P  + +      P+G    +  P +   SP P
Sbjct: 347  PQPDRTHPSAAVPVCPRSASASPLT---PCSVTRSVHRCAPAGERGERRKP-NAGGSPAP 402

Query: 584  SKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAE 643
             +  P+A P++  E  K      EK+     +   + K        PA+P+ +     A 
Sbjct: 403  VRRRPEASPVQKKE-KKDKERENEKEKSALARERSLKK----RQSLPASPRARLSASTAS 457

Query: 644  PATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSP-QSLSDTGYSSDGISSSQSEITGVVQ 702
              +P  KA P +P          +P S   S  P  +L     S  G ++S     G V+
Sbjct: 458  ELSPKSKARPSSPSTS-----WHRPASPCPSPGPGHTLPPKPPSPRGTTASPK---GRVR 509

Query: 703  QEVEQLDSAGVTGPHPPSPSE--IHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQR 760
            ++ E  +S    GP   S S+        S  P   A   APS    P        +   
Sbjct: 510  RKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPT 569

Query: 761  PHSLSITPEA--------------FDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDF 806
              ++  +P A               D +E    + E+   + E R R EQ+   ++  D 
Sbjct: 570  DAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLAEKRRQAREQREREEQERRLQAERD- 628

Query: 807  GSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSG 866
              ++R + +   +E   +    +  AR  E   E   R +      E++ L++       
Sbjct: 629  -KRMREEQLAREAE---ARAEREAEARRRE---EQEAREKAQAEQEEQERLQKQKEEAEA 681

Query: 867  RGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQG 926
            R   +   Q+       +  ++     ++RL        EE++     +E ++       
Sbjct: 682  RSREEAERQRLEREKHFQQQEQERQERRKRL--------EEIMKRTRKSEVSETK----- 728

Query: 927  GLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPAS 986
              ++  + E N+ GS    +   +   P L +E   + E +   P++      S  LPA 
Sbjct: 729  --QKQDSKEANANGSSPEPVKAVEARSPGLQKEAVQKEEPI---PQEPQWSLPSKELPA- 782

Query: 987  TPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQ 1021
              S  +G  P         S + PS  + L    +
Sbjct: 783  --SLVNGLQPLPAHQENGFSTNGPSGDKSLSRTPE 815



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 67/281 (23%), Positives = 90/281 (32%), Gaps = 38/281 (13%)

Query: 377 PAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGS--GPGALPKTGG 434
           P P +  P        + A   PL         P + T    R  P    G    P  GG
Sbjct: 347 PQPDRTHPSAAVPVCPRSASASPL--------TPCSVTRSVHRCAPAGERGERRKPNAGG 398

Query: 435 TTSPKHGRAEHQAASKAAAKPKTMPKERAICPLC-QAELNVGSKSPANYNTCTTCRLQVC 493
           + +P   R E     K   K K    E+    L  +  L      PA+       RL   
Sbjct: 399 SPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPAS----PRARLSAS 454

Query: 494 NLCGFNPTPHL---VEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT 550
                +P          T W                 P P P P    PP     R +  
Sbjct: 455 TASELSPKSKARPSSPSTSW------------HRPASPCPSPGPGHTLPPKPPSPRGTTA 502

Query: 551 SPLKQ--KGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEK 608
           SP  +  +  +    PS   P   S    +AS     A+P A P  +  PS TP+  Q++
Sbjct: 503 SPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAP-ASPAPSPAPSPTPAPPQKE 561

Query: 609 K--TRVPTKAEPMPKPPPETTP-TPATPKVKSGVRRAEPAT 646
           +     PT A  +  PP    P TP+ P   +G    E AT
Sbjct: 562 QPPAETPTDAAVLTSPPAPAPPVTPSKP--MAGTTDREEAT 600



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 51/196 (26%), Positives = 84/196 (42%), Gaps = 24/196 (12%)

Query: 2239 TSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSR 2298
            TS  ++P+  P  P G  G    PAP +    SS   + GP           P A GP  
Sbjct: 59   TSSKQLPL-EPESPSGQVG--PRPAPPQEESPSSEAKSRGPT----------PPAMGPRD 105

Query: 2299 PEMPVGAAREEPLPTTTPAAI-----KEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPG 2353
               P  ++  +P PT  PA+      +E   A     LA ++    A       A+    
Sbjct: 106  ARPPRRSS--QPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEK 163

Query: 2354 FEKEEASQE----ERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQ 2409
             EK +A +E    ER+R+ +EQ L+ E+ R  LE+ ++ +L++  ER    +QR  ++  
Sbjct: 164  EEKAKALREKQLQERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTW 223

Query: 2410 LLVQRELQELQTIKHH 2425
              ++++        HH
Sbjct: 224  AEIRQQRWSWAGALHH 239



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 99/505 (19%), Positives = 154/505 (30%), Gaps = 95/505 (18%)

Query: 744  ERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESS 803
            ER KP + G+    ++RP +  +  +    D+E E+  E+   + E   ++ Q   A   
Sbjct: 390  ERRKPNAGGSPAPVRRRPEASPVQKKE-KKDKERENEKEKSALARERSLKKRQSLPASPR 448

Query: 804  DDFGSQLRHDYVEDSSEGGLSP-------------------LPPQPPA-RAAELTDEDFM 843
                +    +    S     SP                   LPP+PP+ R    + +  +
Sbjct: 449  ARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRV 508

Query: 844  RRQILEMSAEEDNLEEDDTATSGRGL-AKHGTQKGGPRPRPEPSQEPAALPKRRLPHNAT 902
            RR+     +      ED + +  R    K       P P P PS  PA   K + P    
Sbjct: 509  RRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETP 568

Query: 903  TGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPEL 962
            T    L      A     S  + G   R                          +    L
Sbjct: 569  TDAAVLTSPPAPAPPVTPSKPMAGTTDR--------------------------EEATRL 602

Query: 963  EMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQ 1022
              E    + E R R E    L A                          R +R+ E +  
Sbjct: 603  LAEKRRQAREQREREEQERRLQAE-------------------------RDKRMREEQLA 637

Query: 1023 RKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELR 1082
            R+A  R+            E E  R EE+  RE+ +  + EQ+R+       ++ KEE  
Sbjct: 638  REAEARAE----------REAEARRREEQEAREKAQAEQEEQERL-------QKQKEEAE 680

Query: 1083 AQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGG 1142
            A+ R E  +         +      + R+    E + R+  SE S +       EA   G
Sbjct: 681  ARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANG 740

Query: 1143 PSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQ 1202
             S       E   P         E P      P   +    ++E    ++   + L   Q
Sbjct: 741  SSPEPVKAVEARSPGLQKEAVQKEEP-----IPQEPQWSLPSKELPASLVNGLQPLPAHQ 795

Query: 1203 GQAAGARGPHGGPSQPTGPRGLGSF 1227
                   GP G  S    P  L  F
Sbjct: 796  ENGFSTNGPSGDKSLSRTPETLLPF 820



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 138/687 (20%), Positives = 227/687 (33%), Gaps = 81/687 (11%)

Query: 612  VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQ 671
            V  +  P P+P PE  P+P  P + + V    P TP     P       ++ L  +P S 
Sbjct: 17   VVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTP-----PAMKNATSSKQLPLEPESP 71

Query: 672  DASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGSSM 731
                 P+       S     SS+++  G     +   D+        PSP+    V +S 
Sbjct: 72   SGQVGPRPAPPQEES----PSSEAKSRGPTPPAMGPRDARPPRRSSQPSPT---AVPASD 124

Query: 732  RPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWR 791
             P  + +     ER K       E +++R   L+     +   EE    L E +     R
Sbjct: 125  SPPTKQEVKKAGERHKLAK----ERREERAKYLAAKKAVWLEKEEKAKALREKQLQERRR 180

Query: 792  RRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMS 851
            R  EQ+  AE       + +   +E + E   + +        AE+  + +     L  S
Sbjct: 181  RLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKKTWAEIRQQRWSWAGALHHS 240

Query: 852  AEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPE 911
            +          + S   L KH       R     S+  A L       N+ +    L   
Sbjct: 241  SPGHKTSGSRCSVSAVNLPKHVDSIINKR----LSKSSATL------WNSPSRNRSLQLS 290

Query: 912  GGSAEATDG--SGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTG 969
               +   D   + TL    R    + L   G      D G+G DP           SL  
Sbjct: 291  AWESSIVDRLMTPTLSFLARSRSAVTLPRNGR-----DQGRGCDPGRGPTWGRAGASLAR 345

Query: 970  SPE-DRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHR 1028
             P+ DR+            PS      P S S+      S      R   A ++ + R  
Sbjct: 346  GPQPDRTH-----------PSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKP 394

Query: 1029 SHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRE 1088
            + G     +    E   ++++E    +++K RE E+++      ++ + ++ L A  R  
Sbjct: 395  NAGGSPAPVRRRPEASPVQKKE----KKDKERENEKEKSALARERSLKKRQSLPASPRAR 450

Query: 1089 RSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYK 1148
             S +  S LSP   A P      ++     HR +    SP PS          GP     
Sbjct: 451  LSASTASELSPKSKARP------SSPSTSWHRPA----SPCPS---------PGPGHTLP 491

Query: 1149 SGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGA 1208
                   P   S    T +P G        +   SA    ++   K      ++  A  +
Sbjct: 492  -------PKPPSPRGTTASPKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPAS 544

Query: 1209 RGPHGGPSQPTGPRGLGSFEYQDTTDRE-YGQAAQPAAEGTPASLGAAVYEEILQTSQSI 1267
              P   PS    P        +  TD         PA   TP+   A   +    T    
Sbjct: 545  PAPSPAPSPTPAPPQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATRLLA 604

Query: 1268 VRMRQASSRDLAFAEDKKKEKQFLNAE 1294
             + RQA  +      +++++++ L AE
Sbjct: 605  EKRRQAREQ-----REREEQERRLQAE 626



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 35/104 (33%), Positives = 45/104 (43%), Gaps = 15/104 (14%)

Query: 526 GEPTPLPPPTS----QQPPVGAPHRASGTS----PLKQKGPQGLGQPSGPLPAKASPLST 577
           G+P+P PPP S      PP   P   + TS    PL+ + P G   P    P + SP S 
Sbjct: 31  GDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQLPLEPESPSGQVGPRPAPPQEESPSSE 90

Query: 578 KAS--PLPSKASPQ--AKPLRASEPSKTPSSVQEKKTRVPTKAE 617
             S  P P    P+    P R+S+PS T     +     PTK E
Sbjct: 91  AKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSP---PTKQE 131



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 44/219 (20%), Positives = 76/219 (34%), Gaps = 22/219 (10%)

Query: 3648 GDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQ 3707
            G+ G     + G  P     +P A  + + E +   + +         +           
Sbjct: 386  GERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKKRQSLPA 445

Query: 3708 PSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQI 3767
              RA  +   AS+    S+   S P+    +          G    P P   +  ++   
Sbjct: 446  SPRARLSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTAS-- 503

Query: 3768 PSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPST 3827
            P G   R+ + ++     G +   Q+  +A  +++S      +APA+        P PS 
Sbjct: 504  PKGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKES------AAPAS--------PAPSP 549

Query: 3828 ATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP 3866
            A  P PA PP+ EQ       A+ P       + PAP P
Sbjct: 550  APSPTPA-PPQKEQP-----PAETPTDAAVLTSPPAPAP 582



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 46/185 (24%), Positives = 67/185 (36%), Gaps = 25/185 (13%)

Query: 293 AAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFG 352
           A APP V  V+  PP+P      +P PP    P   +  VP     T    +  T     
Sbjct: 11  AGAPPAV--VARTPPEPRPSPEGDPSPP----PPPMSALVPDTPPDTPPAMKNAT----- 59

Query: 353 LGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVF-NDASKEAGPKPLGSGPGPGPAPG 411
                   +S  + ++PE+ + GQ  P    P+    +  +K  GP P   GP     P 
Sbjct: 60  --------SSKQLPLEPESPS-GQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPR 110

Query: 412 AKTEPGARMGPGSG----PGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPL 467
             ++P     P S        + K G        R E +A   AA K   + KE     L
Sbjct: 111 RSSQPSPTAVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKAL 170

Query: 468 CQAEL 472
            + +L
Sbjct: 171 REKQL 175



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 44/139 (31%), Positives = 57/139 (41%), Gaps = 25/139 (17%)

Query: 26  GPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPP------VPGPGPGPGPGPGPGSTSRR 79
           GP    GAG PP+  A     P        + PP      VP   P   P     ++S++
Sbjct: 4   GPRAELGAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPPAMKNATSSKQ 63

Query: 80  L--DPKEPLGNQRAASPTPKQASATTPGHESP-RETRAQGPAGQEADGPRRTLQVDSRTQ 136
           L  +P+ P G Q    P P       P  ESP  E +++GP    A GPR     D+R  
Sbjct: 64  LPLEPESPSG-QVGPRPAP-------PQEESPSSEAKSRGPT-PPAMGPR-----DARPP 109

Query: 137 R--SGRSPSVSPDRGSTPT 153
           R  S  SP+  P   S PT
Sbjct: 110 RRSSQPSPTAVPASDSPPT 128



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 35/131 (26%), Positives = 45/131 (34%), Gaps = 22/131 (16%)

Query: 37  PSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTP 96
           P A  G G  PA  A      PP P P P   P P P   S  +    P         TP
Sbjct: 5   PRAELGAGAPPAVVAR----TPPEPRPSPEGDPSPPPPPMSALVPDTPP--------DTP 52

Query: 97  KQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPS--------VSPDR 148
                 T   + P E   + P+GQ    P    +    ++   R P+          P R
Sbjct: 53  PAMKNATSSKQLPLEP--ESPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPR 110

Query: 149 GSTPTSPYSVP 159
            S+  SP +VP
Sbjct: 111 RSSQPSPTAVP 121



 Score = 36.6 bits (83), Expect = 0.50
 Identities = 28/97 (28%), Positives = 34/97 (35%), Gaps = 6/97 (6%)

Query: 21  AGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRL 80
           A P P PGPG      P +P G    P     R       P        GP   S S+R 
Sbjct: 478 ASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRRKEEAKESPS-----AAGPEDKSQSKRR 532

Query: 81  DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGP 117
              E   +   ASP P  A + TP      +  A+ P
Sbjct: 533 ASNEK-ESAAPASPAPSPAPSPTPAPPQKEQPPAETP 568



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 38/150 (25%), Positives = 54/150 (36%), Gaps = 18/150 (12%)

Query: 31  PGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQR 90
           P +   PS+P+     PA+           P P PGPG    P   S R     P G  R
Sbjct: 461 PKSKARPSSPSTSWHRPAS-----------PCPSPGPGHTLPPKPPSPRGTTASPKGRVR 509

Query: 91  AASPTPKQASATTPGHESPRETRAQG---PAGQEADGPRRTLQVDSRTQRSGRSPSVSPD 147
                 +  SA  P  +S  + RA      A   +  P           +  + P+ +P 
Sbjct: 510 RKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPPAETPT 569

Query: 148 RGSTPTSPYSVPQIAPLPSSTLCPICKTSD 177
             +  TSP   P  AP P +   P+  T+D
Sbjct: 570 DAAVLTSP---PAPAP-PVTPSKPMAGTTD 595



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 36/128 (28%), Positives = 49/128 (38%), Gaps = 22/128 (17%)

Query: 3749 GRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTR 3808
            G  A P       P  R  P G  S  P            PP  AL          P   
Sbjct: 10   GAGAPPAVVARTPPEPRPSPEGDPSPPP------------PPMSALVPDT--PPDTPPAM 55

Query: 3809 GSAPAASQPAGKPQPGPSTATGPQPAGP----PRAE-QTNGSKGTAKAPQQGRAPQ--AQ 3861
             +A ++ Q   +P+  PS   GP+PA P    P +E ++ G    A  P+  R P+  +Q
Sbjct: 56   KNATSSKQLPLEPE-SPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQ 114

Query: 3862 PAPGPGPA 3869
            P+P   PA
Sbjct: 115  PSPTAVPA 122



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 34/136 (25%), Positives = 48/136 (35%), Gaps = 17/136 (12%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFP 3095
            P + A P++PS  T++ +P    P+P              P H  P  P PS     A P
Sbjct: 461  PKSKARPSSPS--TSWHRPASPCPSPG-------------PGHTLPPKP-PSPRGTTASP 504

Query: 3096 PGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPV-PADSRAPLQKPRQTSLADLE 3154
             G     E    +  A  P      +      + +  P  PA S AP   P         
Sbjct: 505  KGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKESAAPASPAPSPAPSPTPAPPQKEQPP 564

Query: 3155 QKVPTNYEVIASPVVP 3170
             + PT+  V+ SP  P
Sbjct: 565  AETPTDAAVLTSPPAP 580


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 80.5 bits (197), Expect = 3e-14
 Identities = 103/398 (25%), Positives = 135/398 (33%), Gaps = 88/398 (22%)

Query: 259 GKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQ---PPQPTKPSTA 315
           G P      GP  P  G+             P  A  PP  GR  P    P +P  PS  
Sbjct: 65  GSPAGAAGAGPAAPAEGA-------------PGAAPEPPPAGRARPGGGGPQRPGPPSPR 111

Query: 316 EPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQG 375
            P  PAG AP  +    P          EG  G    + A+    A              
Sbjct: 112 RPLVPAGPAPPAAKLRPPP---------EGSAGSCAPVPAAAAVAAGP------------ 150

Query: 376 QPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGT 435
           +PAP+           +K AGP  L +  GPGP PG    PG   G  +GPGA     G+
Sbjct: 151 EPAPA---------GPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGS 201

Query: 436 TSPKHGRAEHQAASKAA-------AKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTC 488
            +  +    H AA+ A        A    +PK  A   + Q    VG+ +P         
Sbjct: 202 AALLN---SHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP-------- 250

Query: 489 RLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPT--PLPPPTSQ---QPPVGA 543
                      P+P                     +L  P   P  PPT+     PP  A
Sbjct: 251 -------APAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAA 303

Query: 544 PHRAS-GTSPLKQK---GPQGLGQPSGPLPAKASPLSTKASPLPSK----ASPQAKPLRA 595
            +  S G +P       GP G+    GP  A A+P     +  P +    A P A+ L A
Sbjct: 304 QNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAA 363

Query: 596 SEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
           S P+ T +S+       PT    +P P     P P TP
Sbjct: 364 SGPASTAASM----VIGPTMQGALPSPAAVPPPAPGTP 397



 Score = 66.2 bits (160), Expect = 6e-10
 Identities = 90/329 (27%), Positives = 115/329 (34%), Gaps = 48/329 (14%)

Query: 3604 SSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPG 3663
            S  SQ    A H +H     PE  +     G  G H  +     G  G          PG
Sbjct: 28   SLESQLAASAAHHHHLAPRTPE--VRAAAAGALGNHVVSGSPA-GAAGAGPAAPAEGAPG 84

Query: 3664 RRAAKP---HARDLGRHEARPHSQPSSAPAMPK-------KGQPGYPSSAEYSQPSRASS 3713
                 P    AR  G    RP       P +P        K +P    SA    P  A++
Sbjct: 85   AAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAA 144

Query: 3714 AYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQL-------QGRQAAPGPQQS------- 3759
            A     +         +GPAAL ++A P   P          G+ A PG  Q+       
Sbjct: 145  AVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAAL 204

Query: 3760 ------QSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQ---QALTQARLQQQSQPTTRGS 3810
                   +P+   + +G A+  P  +    G  +Q P     A   A            +
Sbjct: 205  LNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPA 264

Query: 3811 APAASQPAGKPQPGPSTATGP--QPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGP-- 3866
            APAA+ P   P P P+T   P   PAGPP A     +     A Q G +  A PAP P  
Sbjct: 265  APAAAPPP--PPPAPATLARPPGHPAGPPTAAP---AVPPPAAAQNGGSAGAAPAPAPAA 319

Query: 3867 -GPAGVKAGARPGGTPGAPAGQPGADGES 3894
             GPAGV     PG    APA  PG   ES
Sbjct: 320  GGPAGVSGQPGPGAAAAAPA--PGVKAES 346



 Score = 63.5 bits (153), Expect = 4e-09
 Identities = 117/470 (24%), Positives = 154/470 (32%), Gaps = 80/470 (17%)

Query: 8   EGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGP 67
           EG AG     P  A    GP P P     P+ PAG    PAA AAR+    P PGPGPGP
Sbjct: 131 EGSAGSCAPVPAAAAVAAGPEPAPAG---PAKPAG----PAALAARAG---PGPGPGPGP 180

Query: 68  GPGPGPG-----STSRRLDPKEPLGNQRAAS---------------PTPKQASATTPGHE 107
           GPGPGPG       ++ L+    L N   A+               P PK A+  T    
Sbjct: 181 GPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQT 240

Query: 108 SPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSS 167
            P    A  PA      P               +P   P   +T   P   P   P  + 
Sbjct: 241 PPFVGAAAPPAPAAPSPPAAPAPA-----APAAAPPPPPPAPATLARPPGHPAGPPTAAP 295

Query: 168 TLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCG-----FNPNPHL-----TQVKEWLC 217
            + P     +  S  + P           V  Q G       P P +      +V +   
Sbjct: 296 AVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAP 355

Query: 218 LNCQMQRALGMDMTTAPR---SKSQQQLHSPALSPAHSPA------KQPLGKPDQERSRG 268
              Q   A G   T A        Q  L SPA  P  +P       K   G   Q  SR 
Sbjct: 356 PAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRT 415

Query: 269 PGGPQPGSRQ--AETARATSVPGPAQAAA-------PP-------EVGRVSPQPPQP--- 309
           P     G R     T  A  +P P Q          PP       E G++   P Q    
Sbjct: 416 PTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQ 475

Query: 310 -TKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
               + A+P+      PA   +A P  +   +     +  +       +   +    +VQ
Sbjct: 476 MQAQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQ 535

Query: 369 PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGA 418
           P A  Q  P      P++V   A++ A    LG+          +T PGA
Sbjct: 536 PSATLQRSPGVQ---PQLVLGGAAQTAS---LGTATAVQTGTPQRTVPGA 579



 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 96/400 (24%), Positives = 119/400 (29%), Gaps = 70/400 (17%)

Query: 17  PPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGST 76
           P G AG GP     P  G P +AP    + P AG AR         PG G    PGP S 
Sbjct: 67  PAGAAGAGPA---APAEGAPGAAP----EPPPAGRAR---------PGGGGPQRPGPPSP 110

Query: 77  SRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQE--ADGPRRTLQVDSR 134
            R L P  P        P P+ ++    G  +P    A   AG E    GP +     + 
Sbjct: 111 RRPLVPAGPAPPAAKLRPPPEGSA----GSCAPVPAAAAVAAGPEPAPAGPAKPAGPAAL 166

Query: 135 TQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCH 194
             R+G  P   P  G  P                             P +P      Q  
Sbjct: 167 AARAGPGPGPGPGPGPGP----------------------------GPGKPAGPGAAQ-- 196

Query: 195 NKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPA 254
               N      N H         +N      L +    AP +  Q      A +P    A
Sbjct: 197 --TLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254

Query: 255 KQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPST 314
             P   P       P  P         A AT    P   A PP         P    P+ 
Sbjct: 255 PSPPAAP------APAAPAAAPPPPPPAPATLARPPGHPAGPPTAA------PAVPPPAA 302

Query: 315 AEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQ 374
           A+    AG APA  A A     G + Q   G        G    +    + +  P A T 
Sbjct: 303 AQNGGSAGAAPA-PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTL 361

Query: 375 GQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKT 414
               P+     +V     + A P P      P PAPG  T
Sbjct: 362 AASGPASTAASMVIGPTMQGALPSPAAV---PPPAPGTPT 398



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 87/305 (28%), Positives = 104/305 (34%), Gaps = 45/305 (14%)

Query: 3623 PPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRA-AKPHARDLGRHEARP 3681
            PP   L P  EG  G  A             +    G EP     AKP         A P
Sbjct: 121  PPAAKLRPPPEGSAGSCAPVPAA--------AAVAAGPEPAPAGPAKPAGPAALAARAGP 172

Query: 3682 HSQPSSAPAM-PKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
               P   P   P  G+P  P +A+    S A    HHA+         ++GPAAL    +
Sbjct: 173  GPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA--APAVSLVNNGPAALLPLPK 230

Query: 3741 PQAQ------PQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQAL 3794
            P A       P   G  A P P  + SP +   P+  A+  P        L   P   A 
Sbjct: 231  PAAPGTVIQTPPFVGAAAPPAPA-APSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289

Query: 3795 TQARLQQQSQPTTR---GSAPAASQP---AGKP-----QPGP-STATGPQP--------- 3833
                      P      GSA AA  P   AG P     QPGP + A  P P         
Sbjct: 290  PPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKR 349

Query: 3834 ---AGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGA 3890
               A PP A+    S   + A      P  Q A  P PA V   A PG   G P G  GA
Sbjct: 350  VVQAAPPAAQTLAASGPASTAASMVIGPTMQGAL-PSPAAVPPPA-PGTPTGLPKGAAGA 407

Query: 3891 DGESV 3895
              +S+
Sbjct: 408  VTQSL 412



 Score = 54.7 bits (130), Expect = 2e-06
 Identities = 97/388 (25%), Positives = 139/388 (35%), Gaps = 66/388 (17%)

Query: 1360 PASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSP--SPSSTAH 1417
            PA+P +  +      +  P  PA    AP P   P     PA+PA +   P  +P++ A 
Sbjct: 231  PAAPGTVIQTPPFVGAAAPPAPA----APSPPAAP----APAAPAAAPPPPPPAPATLAR 282

Query: 1418 SYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASD-GEGGTPQPSRAYSYFASS 1476
              GH P      +     P A     +AG A    P +    G  G P P  A    A+ 
Sbjct: 283  PPGH-PAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAA---AAP 338

Query: 1477 SPPLSPSSPSESPTFSP------GKMGPRATAEFSTQTPS-----PAPASDMPRSPGAPT 1525
            +P +   SP      +P         GP +TA      P+     P+PA+  P +PG PT
Sbjct: 339  APGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398

Query: 1526 PSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPT 1585
              P  A G  T     TP                T +   ++ T  V A     P  +PT
Sbjct: 399  GLPKGAAGAVTQSLSRTP--------------TATTSGIRATLTPTVLAPRLPQPPQNPT 444

Query: 1586 ETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRI 1645
              Q               QL      PPG   V S   +G L +    AL        + 
Sbjct: 445  NIQN-------------FQL------PPGMVLVRS--ENGQLLMIPQQALAQMQ---AQA 480

Query: 1646 SSVPGTSRVEPGPRTPGTA-VVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP 1704
             + P T+ + P P TP +A  V + T   P   I+  Q    T +   ++          
Sbjct: 481  HAQPQTT-MAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPSAT 539

Query: 1705 GRQSTAVQPLVINLNAQEHTFLATATTV 1732
             ++S  VQP ++   A +   L TAT V
Sbjct: 540  LQRSPGVQPQLVLGGAAQTASLGTATAV 567



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 103/388 (26%), Positives = 137/388 (35%), Gaps = 85/388 (21%)

Query: 2   GNEVSLEGGAGDGPLPP-------GGAGPG-PGP----------GPGPGAGK---PPSAP 40
           G     EG  G  P PP       GG GP  PGP          GP P A K   PP   
Sbjct: 74  GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGS 133

Query: 41  AGG-GQLPAAGAARSTAVPPVPGP----GP-------GPGPGPGPGSTSRRLDPKEPLGN 88
           AG    +PAA A  +   P   GP    GP       GPGPGPGPG       P +P G 
Sbjct: 134 AGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPG-PGPGPGPGKPAG- 191

Query: 89  QRAASPTPKQASATTPGHESPRETRA---QGPAG----QEADGPRRTLQ----VDSRTQR 137
              A+ T   ++A    H +     +    GPA      +   P   +Q    V +    
Sbjct: 192 -PGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250

Query: 138 SGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLC--PICKTSDLTSTPSQPNFNTCTQCHN 195
           +  +P  SP     P +P + P   P   +TL   P       T+ P+ P          
Sbjct: 251 APAAP--SPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP-----PPAAA 303

Query: 196 KVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS-PAHSPA 254
           +     G  P P                 A G     + +        +PA    A SP 
Sbjct: 304 QNGGSAGAAPAP---------------APAAGGPAGVSGQPGPGAAAAAPAPGVKAESPK 348

Query: 255 KQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPST 314
           +     P   ++    GP      A TA A+ V GP    A P    V   PP P  P T
Sbjct: 349 RVVQAAPPAAQTLAASGP------ASTA-ASMVIGPTMQGALPSPAAV--PPPAPGTP-T 398

Query: 315 AEPRPPAG---EAPAKSATAVPAGLGAT 339
             P+  AG   ++ +++ TA  +G+ AT
Sbjct: 399 GLPKGAAGAVTQSLSRTPTATTSGIRAT 426



 Score = 54.3 bits (129), Expect = 2e-06
 Identities = 64/230 (27%), Positives = 76/230 (33%), Gaps = 37/230 (16%)

Query: 2132 GPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQLLPSTATV---R 2188
            GP  +      P  P  L     P   P PG     GP    G    Q L  +A +    
Sbjct: 149  GPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSH 208

Query: 2189 AADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIA 2248
             A     S +N   AA LP+                 +P A G +   P       P  A
Sbjct: 209  HAAAPAVSLVNNGPAALLPLP----------------KPAAPGTVIQTPPFVGAAAPP-A 251

Query: 2249 PRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAARE 2308
            P  P  P      PAP+  P A+  PP   P  L +P          P  P  P  AA  
Sbjct: 252  PAAPSPPAA----PAPAA-PAAAPPPPPPAPATLARP----------PGHPAGPPTAAPA 296

Query: 2309 EPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPG-GGSGALSRPGFEKE 2357
             P P         A  APAPAP AG        PG G + A   PG + E
Sbjct: 297  VPPPAAAQNG-GSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAE 345



 Score = 52.0 bits (123), Expect = 1e-05
 Identities = 70/248 (28%), Positives = 82/248 (33%), Gaps = 33/248 (13%)

Query: 2113 GRHGSGGGGPDLVQYQPQHGPGLSAPQS-LVPLRPGLLGNPTFPEGHPSPGNLAQYGPAA 2171
            GR   GGGGP          PG  +P+  LVP  P        P    S G+ A   PAA
Sbjct: 93   GRARPGGGGPQR--------PGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPV-PAA 143

Query: 2172 GQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASG 2231
                A  +  P+     A           P A        P     P    G  +P   G
Sbjct: 144  AAVAAGPEPAPAGPAKPAG----------PAALAARAGPGPGPGPGPGPGPGPGKPAGPG 193

Query: 2232 GITAVPLTS--LTRVPMIAPRVPL---GPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPA 2286
                +  ++  L      AP V L   GP  L   P P+        PP  G       A
Sbjct: 194  AAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGA------A 247

Query: 2287 AAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQ--KPPADAAPGG 2344
            A  AP A  P     P   A   P P   PA +    G PA  P A     PPA A  GG
Sbjct: 248  APPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGG 307

Query: 2345 GSGALSRP 2352
             +GA   P
Sbjct: 308  SAGAAPAP 315



 Score = 51.2 bits (121), Expect = 2e-05
 Identities = 92/435 (21%), Positives = 146/435 (33%), Gaps = 82/435 (18%)

Query: 1205 AAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPA-AEGTPASLGAAVYEEILQT 1263
            AA A GP   P+ P  P G  +   +       G    P    G PA  GAA   + L  
Sbjct: 144  AAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAA---QTLNG 200

Query: 1264 SQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQL--AAPV 1321
            S +++    A++  ++           +N   A + P+ +   P T   +P  +  AAP 
Sbjct: 201  SAALLNSHHAAAPAVSL----------VNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPP 250

Query: 1322 SFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTP 1381
            + + P+   +                     P    ++P  P  A   +  P     G P
Sbjct: 251  APAAPSPPAAPA-------------------PAAPAAAPPPPPPAPATLARPPGHPAGPP 291

Query: 1382 ATTAVAPCPAGLPRGYMTPAS---------PAGSERSPSPSSTAHSYGHSPTTANYGSQT 1432
                  P PA    G    A+         PAG    P P + A +        +     
Sbjct: 292  TAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVV 351

Query: 1433 EDLPQAPSGLAAAGRAAREKPLSASDG-EGGTPQPSRAYSYFASSSPPLSPSSPSESPTF 1491
            +  P A   LAA+G A+    +      +G  P P        ++ PP +P +P+  P  
Sbjct: 352  QAAPPAAQTLAASGPASTAASMVIGPTMQGALPSP--------AAVPPPAPGTPTGLPKG 403

Query: 1492 SPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESS 1551
            + G +         TQ+ S  P +         TP+ +  +  Q P  P+       ++ 
Sbjct: 404  AAGAV---------TQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTN-----IQNF 449

Query: 1552 QEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPG 1611
            Q  P MV  L    + Q  M+       P  +  + Q   H   QTT      + P P  
Sbjct: 450  QLPPGMV--LVRSENGQLLMI-------PQQALAQMQAQAHAQPQTT------MAPRPAT 494

Query: 1612 PPGFPRVPSAGADGP 1626
            P   P V  +    P
Sbjct: 495  PTSAPPVQISTVQAP 509



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 74/317 (23%), Positives = 103/317 (32%), Gaps = 38/317 (11%)

Query: 1379 GTPATTAVAPCPAGLPRGYMTPASPA----GSERSPSPSSTAHSYGHSPTTANYGSQTED 1434
            G      V+  PAG       PA+PA    G+   P P+  A   G  P     G  +  
Sbjct: 56   GALGNHVVSGSPAGAAGA--GPAAPAEGAPGAAPEPPPAGRARPGGGGPQRP--GPPSPR 111

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPG 1494
             P  P+G A      R  P    +G  G+  P  A +  A+   P +P+ P++       
Sbjct: 112  RPLVPAGPAPPAAKLRPPP----EGSAGSCAPVPAAAAVAAGPEP-APAGPAKPA----- 161

Query: 1495 KMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQ------TPHRPSTPRLVWQ 1548
              GP A A  +   P P P       PG P   P  AQ           H  + P +   
Sbjct: 162  --GPAALAARAGPGPGPGPGPGPGPGPGKPA-GPGAAQTLNGSAALLNSHHAAAPAV--- 215

Query: 1549 ESSQEAPFMVITLASDASSQTRM-----VHASASTSPLCS--PTETQPTTHGYSQTTPPS 1601
                  P  ++ L   A+  T +     V A+A  +P     P    P     +   PP 
Sbjct: 216  SLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP 275

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTP 1661
                   PPG P  P   +     P A    G+  A            G S  +PGP   
Sbjct: 276  APATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSG-QPGPGAA 334

Query: 1662 GTAVVDLRTAVKPTPII 1678
              A      A  P  ++
Sbjct: 335  AAAPAPGVKAESPKRVV 351



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 83/313 (26%), Positives = 109/313 (34%), Gaps = 64/313 (20%)

Query: 1371 GMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGS 1430
            G P   GP +P    V   PAG       PA PA   R P P  +A S    P  A   +
Sbjct: 100  GGPQRPGPPSPRRPLV---PAG-------PAPPAAKLR-PPPEGSAGSCAPVPAAAAVAA 148

Query: 1431 QTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPT 1490
              E  P  P+    AG AA    L+A  G G  P P            P  P+ P  + T
Sbjct: 149  GPEPAPAGPA--KPAGPAA----LAARAGPGPGPGPGP-----GPGPGPGKPAGPGAAQT 197

Query: 1491 FSPGKMGPRATAEFSTQTPSPAPA-SDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQE 1549
             +        +A       + APA S +   P A  P P          +P+ P  V Q 
Sbjct: 198  LN-------GSAALLNSHHAAAPAVSLVNNGPAALLPLP----------KPAAPGTVIQ- 239

Query: 1550 SSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEP 1609
                 P  V   A  A +      A A  +P  +P    P         P ++++ P  P
Sbjct: 240  ----TPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPP--------APATLARPPGHP 287

Query: 1610 PGPP-GFPRV--PSAGADGPLALYGWGALPAENISL---CRISSVPGTSRVEPGPRTPGT 1663
             GPP   P V  P+A  +G  A    GA PA   +      +S  PG       P  PG 
Sbjct: 288  AGPPTAAPAVPPPAAAQNGGSA----GAAPAPAPAAGGPAGVSGQPGPGAAAAAP-APGV 342

Query: 1664 AVVDLRTAVKPTP 1676
                 +  V+  P
Sbjct: 343  KAESPKRVVQAAP 355



 Score = 45.8 bits (107), Expect = 8e-04
 Identities = 64/247 (25%), Positives = 79/247 (31%), Gaps = 38/247 (15%)

Query: 249 PAHSPAKQPLGKPDQERSRGPG-GPQPGSRQAETARATSVPGPAQA------------AA 295
           PA +   +P G        GPG GP PG          + PG AQ             AA
Sbjct: 152 PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA 211

Query: 296 PPEVGRVSPQP------PQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGK 349
            P V  V+  P      P+P  P T    PP   A A  A A P+   A           
Sbjct: 212 APAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPA---- 267

Query: 350 LFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPA 409
                A      +     +P     G P  +   P      A++  G     +G  P PA
Sbjct: 268 ----AAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPA---AAQNGG----SAGAAPAPA 316

Query: 410 PGAKTEPGARMGPGSGPGALPKTGG--TTSPKH--GRAEHQAASKAAAKPKTMPKERAIC 465
           P A    G    PG G  A     G    SPK     A   A + AA+ P +      I 
Sbjct: 317 PAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIG 376

Query: 466 PLCQAEL 472
           P  Q  L
Sbjct: 377 PTMQGAL 383



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 76/302 (25%), Positives = 101/302 (33%), Gaps = 48/302 (15%)

Query: 1360 PASPSSASKEIGMPFSQGPGT----PATTAVAPCPAGLPRGYMTPASPAG--SERSPSPS 1413
            PA P+  + ++  P     G+    PA  AVA  P   P G   PA PA   +   P P 
Sbjct: 116  PAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175

Query: 1414 -STAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSY 1472
                   G  P         + L  + + L +   AA    L  +      P P  A   
Sbjct: 176  PGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPG 235

Query: 1473 FASSSPPL-----SPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPS 1527
                +PP       P+  + SP  +P    P A    +   P PAPA+ + R PG P   
Sbjct: 236  TVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAA----APPPPPPAPAT-LARPPGHPAGP 290

Query: 1528 PMVAQGTQTPHRPST----------------PRLVWQESSQEAPFMVITLASDASSQTRM 1571
            P  A     P                     P  V  +    A          A S  R+
Sbjct: 291  PTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRV 350

Query: 1572 VHA---SASTSPLCSPTETQ------PTTHGYSQTTPPSVSQLPPEPPG-PPGFPRVPSA 1621
            V A   +A T     P  T       PT  G      PS + +PP  PG P G P+  +A
Sbjct: 351  VQAAPPAAQTLAASGPASTAASMVIGPTMQG----ALPSPAAVPPPAPGTPTGLPK-GAA 405

Query: 1622 GA 1623
            GA
Sbjct: 406  GA 407



 Score = 42.0 bits (97), Expect = 0.012
 Identities = 92/426 (21%), Positives = 155/426 (36%), Gaps = 76/426 (17%)

Query: 2169 PAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASV-------LRPMVR 2221
            P   Q T     +  +++V+   G   +T+ + +   +   TQP  V         P+V 
Sbjct: 684  PPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGVGKQGQPTPLV- 742

Query: 2222 GGMYRPYASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVY 2281
              + +P   G +   P  +LT+ PM+A R P     L         P    + P + PV 
Sbjct: 743  --IQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTT-------PQQIQLNPLQ-PVP 792

Query: 2282 LGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAA 2341
            + KPA    PG    S       AA++  L      + ++       A +AG     ++A
Sbjct: 793  VVKPAVL--PGTKALSAVSAQAAAAQKNKLKEPGGGSFRDDDDINDVASMAGVNLSEESA 850

Query: 2342 PGGGSGALSRPGFEKEEASQEERQRKQQEQLLQ--LERERVELEKLRQLRLQEELERERV 2399
                + +        E      R  K +  LLQ  L+R  +E+ K   +    EL  + V
Sbjct: 851  RILATNS--------ELVGTLTRSCKDETFLLQAPLQRRILEIGKKHGIT---ELHPDVV 899

Query: 2400 ELQRHREEEQLLVQRELQEL-QTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQL 2458
                H  +++L  Q  ++++ +T +      + ++R        EQ +  R QL+  +QL
Sbjct: 900  SYVSHATQQRL--QNLVEKISETAQQKNFSYKDDDRY-------EQASDVRAQLKFFEQL 950

Query: 2459 QQQLQQQLEEQ---------KQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAA 2509
             Q  +Q+ +EQ         K R +   P       +   +   ELAQ  Q    LT  A
Sbjct: 951  DQIEKQRKDEQEREILMRAAKSRSRQEDPEQLRLKQKAKEMQQQELAQMRQRDANLTALA 1010

Query: 2510 FI------------------------AMAGPEGLGQPREPVLHRGLPSSASDMSLQTEEQ 2545
             I                         + G  G+G PR+    R    +  D+    E +
Sbjct: 1011 AIGPRKKRKVDCPGPGSGAEGSGPGSVVPGSSGVGTPRQFTRQRITRVNLRDLIFCLENE 1070

Query: 2546 WEASRS 2551
             E S S
Sbjct: 1071 RETSHS 1076



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 33/108 (30%), Positives = 41/108 (37%), Gaps = 13/108 (12%)

Query: 3810 SAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPA 3869
            +APA   P   P+P P+    P   GP R             P   R P   PA GP P 
Sbjct: 76   AAPAEGAPGAAPEPPPAGRARPGGGGPQRP-----------GPPSPRRPLV-PA-GPAPP 122

Query: 3870 GVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTEAVSA 3917
              K    P G+ G+ A  P A   +   +  P G A+ AG    A  A
Sbjct: 123  AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARA 170



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 30/113 (26%), Positives = 43/113 (38%), Gaps = 4/113 (3%)

Query: 522 EGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASP 581
           EG+ G     PP    +P  G P R    SP +   P G   P+  L       +   +P
Sbjct: 80  EGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAP 139

Query: 582 LPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPK 634
           +P+ A+  A P    EP+    +       +  +A P P P P   P P   K
Sbjct: 140 VPAAAAVAAGP----EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGK 188



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 40/101 (39%), Positives = 45/101 (44%), Gaps = 12/101 (11%)

Query: 3039 AAAPATP---SGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFP 3095
            AAAPA     +GP A   P  +P AP     +  P   G  A  AP  P P   PAPA  
Sbjct: 210  AAAPAVSLVNNGPAALL-PLPKPAAPGTVIQT--PPFVGAAAPPAPAAPSPPAAPAPA-A 265

Query: 3096 PGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPA 3136
            P A+ P  P  P   A RP GH AG    P T +   P PA
Sbjct: 266  PAAAPPPPPPAPATLA-RPPGHPAG----PPTAAPAVPPPA 301



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 39/106 (36%), Positives = 43/106 (40%), Gaps = 21/106 (19%)

Query: 2248 APRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAR 2307
            +PR PL P G    PAP   P A   PP EG      P  A A  A GP     P G A+
Sbjct: 109  SPRRPLVPAG----PAP---PAAKLRPPPEGSAGSCAPVPAAAAVAAGPE--PAPAGPAK 159

Query: 2308 EEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPG 2353
                    PAA+   AG P P P  G        PG G G  + PG
Sbjct: 160  P-----AGPAALAARAG-PGPGPGPGP------GPGPGPGKPAGPG 193



 Score = 40.8 bits (94), Expect = 0.027
 Identities = 62/255 (24%), Positives = 88/255 (34%), Gaps = 54/255 (21%)

Query: 527 EPTPLPPPTSQQPPVGAPHRASGTSPLKQKGP-QGLGQPSGPLPAK-------------- 571
           EP P  P     P   A     G  P    GP  G G+P+GP  A+              
Sbjct: 151 EPAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHA 210

Query: 572 ASPLSTKAS-------PLPSKASP----QAKPL--RASEPSKT-PSSVQEKKTRVPTKAE 617
           A+P  +  +       PLP  A+P    Q  P    A+ P+   PS         P  A 
Sbjct: 211 AAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270

Query: 618 PMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE----------APKGGEAEDLVGK 667
           P P P P T   P  P   +G   A PA P   A             AP  G    + G+
Sbjct: 271 PPPPPAPATLARP--PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQ 328

Query: 668 PYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKV 727
           P    A+ +P         + G+ +   +   VVQ       +   +GP   + S +  +
Sbjct: 329 PGPGAAAAAP---------APGVKAESPK--RVVQAAPPAAQTLAASGPASTAASMV--I 375

Query: 728 GSSMRPLLQAQGLAP 742
           G +M+  L +    P
Sbjct: 376 GPTMQGALPSPAAVP 390



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 68/257 (26%), Positives = 93/257 (36%), Gaps = 22/257 (8%)

Query: 3660 EEPGR--RAAKPHARDLGRHEARPHSQPSSAPAMPKKG---QPGYPSSAEYSQPSRASSA 3714
            E P R  +AA P A+ L        S P+S  A    G   Q   PS A    P+  +  
Sbjct: 345  ESPKRVVQAAPPAAQTLAA------SGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPT 398

Query: 3715 YHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASR 3774
                  +   ++     P A  S       P +   +    PQ   +  + Q+P G    
Sbjct: 399  GLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPTNIQNFQLPPGMV-- 456

Query: 3775 QPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGP-QP 3833
                 + + G  L  PQQAL Q + Q  +QP T   AP  + P   P    ST   P  P
Sbjct: 457  ---LVRSENGQLLMIPQQALAQMQAQAHAQPQTT-MAPRPATPTSAPPVQISTVQAPGTP 512

Query: 3834 AGPPRAEQTNGSKGTAKAPQQGRAPQA--QPAPGPGPAGVKAGARPGGTPG-APAGQPGA 3890
                +   T   K  ++A Q    P A  Q +PG  P  V  GA    + G A A Q G 
Sbjct: 513  IIARQVTPTTIIKQVSQA-QTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGT 571

Query: 3891 DGESVFSKILPGGAAEQ 3907
               +V        AA +
Sbjct: 572  PQRTVPGATTTSSAATE 588



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 40/112 (35%), Positives = 42/112 (37%), Gaps = 29/112 (25%)

Query: 2270 ASSVPPAEGPVYLGK---PAAAKAPGAGGPSRPE--------MPVG----AAREEPLP-- 2312
            A    PAEG         PA    PG GGP RP         +P G    AA+  P P  
Sbjct: 73   AGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEG 132

Query: 2313 -----TTTPAAIKEAAGAPAPAPLAGQKPPADAA------PGGGSGALSRPG 2353
                    PAA   AAG P PAP    KP   AA      PG G G    PG
Sbjct: 133  SAGSCAPVPAAAAVAAG-PEPAPAGPAKPAGPAALAARAGPGPGPGPGPGPG 183



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 66/278 (23%), Positives = 89/278 (32%), Gaps = 66/278 (23%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQPPAPQYSAGS------------------GGPTQNGFPA 3077
            P +   P  P+GP A    + +PP P+ SAGS                   GP +   PA
Sbjct: 107  PPSPRRPLVPAGP-APPAAKLRPP-PEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPA 164

Query: 3078 HQAPTY-PGPSTYPAPAFPPGASYPAEPGLP---NQQAFRPTGHYAG------------- 3120
              A    PGP   P P   PG   PA PG     N  A     H+A              
Sbjct: 165  ALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAA 224

Query: 3121 --QTPMPTTQSTLF-----------PVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASP 3167
                P P    T+            P PA + +P   P   + A      P     +A P
Sbjct: 225  LLPLPKPAAPGTVIQTPPFVGAAAPPAPA-APSPPAAPAPAAPAAAPPPPPPAPATLARP 283

Query: 3168 VVPMSSAPSETSYSGP--AVSSGYEQGKVP-EVPRAGDRGSVSQSPAPTYPSDSHYTSLE 3224
                +  P+      P  A  +G   G  P   P AG    VS  P P   + +    ++
Sbjct: 284  PGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVK 343

Query: 3225 QNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSS 3262
               P+  V             +  P +Q L   GP S+
Sbjct: 344  AESPKRVVQ------------AAPPAAQTLAASGPAST 369



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 123/509 (24%), Positives = 190/509 (37%), Gaps = 91/509 (17%)

Query: 2714 ESLACQTEPDGQAQGVAGPQLVG----PTAISPYLPGIQIVTP----GPLGRFEKKKPDP 2765
            ++LA        A  V GP + G    P A+ P  PG     P    G + +   + P  
Sbjct: 359  QTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTA 418

Query: 2766 LEIGYQAHLPPESLSQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHVSPQ 2825
               G +A L P  L+  +  QPP++P  + +    L P  +L  S        +  + PQ
Sbjct: 419  TTSGIRATLTPTVLAPRLP-QPPQNPTNIQN--FQLPPGMVLVRS-----ENGQLLMIPQ 470

Query: 2826 KHFTADSALRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGG--LGSQVSA 2883
            +   A + ++ Q   +P  T+      P+P +PT+    +   S  Q  G   +  QV+ 
Sbjct: 471  Q---ALAQMQAQAHAQPQTTMA-----PRPATPTSAPPVQ--ISTVQAPGTPIIARQVT- 519

Query: 2884 LPPNSLVRKVKR---------TLPSPPPEEAHLPLAGQA-SPQLYAASLLQRGLTGPTTV 2933
              P +++++V +         TL   P  +  L L G A +  L  A+ +Q G T   TV
Sbjct: 520  --PTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTASLGTATAVQTG-TPQRTV 576

Query: 2934 PA--TKASLLRELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLA 2991
            P   T +S   E   +++  ++  + L K  A   ++  E  A +K L   +   K   A
Sbjct: 577  PGATTTSSAATETMENVKKCKNFLSTLIKL-ASSGKQSTETAANVKELVQNLLDGKIE-A 634

Query: 2992 KDRGGRDYPPLRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDF---PATAAAPATPSGP 3048
            +D   R Y                ELN       ++P    V F      A    TP   
Sbjct: 635  EDFTSRLY---------------RELN-------SSPQPYLVPFLKRSLPALRQLTPDSA 672

Query: 3049 TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPP--GASYPAEPGL 3106
               QQ + QPP P   A +         + Q       +T  +   PP    + P + G+
Sbjct: 673  AFIQQSQQQPPPPTSQATTALTAVVLSSSVQRTAGKTAATVTSALQPPVLSLTQPTQVGV 732

Query: 3107 PNQQAFRPTGHYAGQTPMP-----TTQSTLFPVP------ADSRAPLQKPRQTSLADLEQ 3155
              Q   +PT     Q P P       Q TL   P        +R  L  P+Q  L  L Q
Sbjct: 733  GKQG--QPTPLVIQQPPKPGALIRPPQVTLTQTPMVALRQPHNRIMLTTPQQIQLNPL-Q 789

Query: 3156 KVPTNYEVIASPVVPMSSAPSETSYSGPA 3184
             VP    V+   V+P + A S  S    A
Sbjct: 790  PVP----VVKPAVLPGTKALSAVSAQAAA 814



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 27/73 (36%), Positives = 35/73 (47%), Gaps = 12/73 (16%)

Query: 3027 TPAGQFVDFPATAAAPATPS--GPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYP 3084
            +PAG      A  A PA P+   P A  +P   PPA +   G GGP + G P+ + P  P
Sbjct: 66   SPAG------AAGAGPAAPAEGAPGAAPEP---PPAGRARPGGGGPQRPGPPSPRRPLVP 116

Query: 3085 -GPSTYPAPAFPP 3096
             GP+   A   PP
Sbjct: 117  AGPAPPAAKLRPP 129



 Score = 35.8 bits (81), Expect = 0.86
 Identities = 52/197 (26%), Positives = 73/197 (37%), Gaps = 22/197 (11%)

Query: 3036 PATAAAPATPSGP-TAFQQPRF----QPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYP 3090
            PA       P+ P T  Q P F     PPAP   +    P      A   P  P P+T  
Sbjct: 222  PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLA 281

Query: 3091 APAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQS------TLFPVP-ADSRAPLQ 3143
             P   P     A P +P   A +  G  AG  P P   +      +  P P A + AP  
Sbjct: 282  RPPGHPAGPPTAAPAVPPPAAAQ-NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340

Query: 3144 KPRQTSLADLEQKVPTNYEVIASPVVPMSSAPS-------ETSYSGPAVSSGYEQGKVPE 3196
              +  S   + Q  P   + +A+   P S+A S       + +   PA       G    
Sbjct: 341  GVKAESPKRVVQAAPPAAQTLAAS-GPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTG 399

Query: 3197 VPRAGDRGSVSQSPAPT 3213
            +P+ G  G+V+QS + T
Sbjct: 400  LPK-GAAGAVTQSLSRT 415



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 48/209 (22%), Positives = 75/209 (35%), Gaps = 36/209 (17%)

Query: 1480 LSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGA---PTPSPMVAQGTQT 1536
            L+P +P E    + G +G    +          PA+    +PGA   P P+     G   
Sbjct: 43   LAPRTP-EVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGG 101

Query: 1537 PHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTET--------Q 1588
            P RP  P          +P   +  A  A    ++      ++  C+P           +
Sbjct: 102  PQRPGPP----------SPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE 151

Query: 1589 PTTHGYSQTTPPS--VSQLPPEP-PGP-------PGFPRVPSAG--ADGPLALYGWGALP 1636
            P   G ++   P+   ++  P P PGP       PG P  P A    +G  AL       
Sbjct: 152  PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA 211

Query: 1637 AENISLCRISSVPGTSRVEPGPRTPGTAV 1665
            A  +SL  +++ P      P P  PGT +
Sbjct: 212  APAVSL--VNNGPAALLPLPKPAAPGTVI 238



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 49/191 (25%), Positives = 63/191 (32%), Gaps = 41/191 (21%)

Query: 2160 SPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPM 2219
            +PG + Q  P  G         PS     A           P AA  P    PA++ RP 
Sbjct: 233  APGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAA--------PAAAPPPPPPAPATLARPP 284

Query: 2220 VRGGMYRPYASGGITAVPLT----------SLTRVPMIAPRVPLGPTGLYRYPAP----- 2264
                    + +G  TA P            S    P  AP    GP G+   P P     
Sbjct: 285  -------GHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAG-GPAGVSGQPGPGAAAA 336

Query: 2265 ---------SRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPS-RPEMPVGAAREEPLPTT 2314
                     S   +  + PPA   +    PA+  A    GP+ +  +P  AA   P P T
Sbjct: 337  APAPGVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGT 396

Query: 2315 TPAAIKEAAGA 2325
                 K AAGA
Sbjct: 397  PTGLPKGAAGA 407


>gi|112421108 capicua homolog [Homo sapiens]
          Length = 1608

 Score = 77.0 bits (188), Expect = 3e-13
 Identities = 193/883 (21%), Positives = 289/883 (32%), Gaps = 177/883 (20%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPA--------GGGQLPAAGAARSTAVPPVPGPGPG 66
            P PP   G G G  P   A  P S+ A        G G   A  + + +   P+  P PG
Sbjct: 518  PDPPVAFGKGYGSAPSSSASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPG 577

Query: 67   PGPGPGPGSTSRRLDPKEPLGNQRAAS--------PTPKQASATTPGHESPRETRAQGPA 118
             G GP   S + R  P +P   +R           P P   +A   G  +  +T    P 
Sbjct: 578  AG-GPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIAAPPSGGGNILQTLVLPPN 636

Query: 119  GQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP---SSTLCPICKT 175
             +E +G    +        S  +PS++    + P S  +   +  +    SST  PI   
Sbjct: 637  KEEQEGGGARVP-------SAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASK 689

Query: 176  SDLTSTPSQPNFNTCTQCHNKVC---------------------NQCGFNPNPHLTQVKE 214
               TS  ++ + N       ++                      +    +P PHL     
Sbjct: 690  PFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHL----- 744

Query: 215  WLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQP 274
                   +   L   +  AP + +   + +P       PA Q + +        PGG   
Sbjct: 745  -------VAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQG------APGGGTT 791

Query: 275  GSRQAETARATSVPGPAQAAAPPEVGRVSP----QPPQPTKPSTAEPRPPAGEAPAKSAT 330
                A      + P P     P  +G+       Q   PT P   +  P    AP   A 
Sbjct: 792  AGSGAGAGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAA 851

Query: 331  AVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFND 390
            A P+G   T       T   F L     T    L +           AP+ G P  +   
Sbjct: 852  A-PSGPAPT-------TSIRFTLPPGTSTNGKVLAAT----------APTPGIP--ILQS 891

Query: 391  ASKEAGPKPLGSGPGPGPAPGAKTE--PGARMGPGSGPGALPKTGGTTSP---------- 438
                  PK     P   P PG   +  PG  + P + P    + GG   P          
Sbjct: 892  VPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSV 951

Query: 439  --KHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLC 496
              ++G        +    P + P    + PL  A L   +  P      ++ R+      
Sbjct: 952  PVQNGAQPPSKIIQLTPVPVSTPSG-LVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSA 1010

Query: 497  GFNPTP----HLVEKTEWLCLNCQTKRLLEG--SLGEPTPL---PPPTSQQPPVGAPHRA 547
            G +  P        +   +     T  +  G  SLG   P    P  ++ Q P+ AP + 
Sbjct: 1011 GGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQAPLLAPGQV 1070

Query: 548  SGTSPLKQKG-PQGLGQPSGPLPA---KASPLSTKASPL--PSKASPQAKPLRASEPSKT 601
             G SP+     P     P GP+       SP  T ++PL  PS+A P      A+  +  
Sbjct: 1071 -GVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPP 1129

Query: 602  PSSVQEKKTRVPTKAEPMPKPP-PETT---------------PTPATP-KVK-------- 636
             +++  K    P  A P P  P P  T               P+P  P KVK        
Sbjct: 1130 AATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPV 1189

Query: 637  -------SGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDG 689
                   SG     P  P+       P   E+E L G+P        P++ + T  SS  
Sbjct: 1190 GSFEAGASGRPGPAPRQPLEPGPVREPTAPESE-LEGQPTPPAPPPLPETWTPTARSSPP 1248

Query: 690  ISSSQSEITGVVQQEV----------------EQLDSAGVTGPHPPSPSEIHKV---GSS 730
            +     E T     E                 + L++ G   P PPSP+    V   GSS
Sbjct: 1249 LPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRG-EPPTPPSPAPAPAVAPGGSS 1307

Query: 731  MRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDS 773
                 +A G  P  +    ++GTG++ K RP  L  T ++ D+
Sbjct: 1308 ESSSGRAAGDTPERKE---AAGTGKKVKVRPPPLKKTFDSVDN 1347



 Score = 69.7 bits (169), Expect = 5e-11
 Identities = 132/532 (24%), Positives = 173/532 (32%), Gaps = 110/532 (20%)

Query: 7    LEGGAGDG-PLPP-------GGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVP 58
            L G  G G P PP       G  G G   G G GAG  P+ P   G L      ++  + 
Sbjct: 764  LVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPNGPVPLGILQPGALGKAGGIT 823

Query: 59   PV--------------PGPGPGPG------PGPGPGSTSRRLDPKEPLGNQR---AASPT 95
             V              P P P PG       GP P ++ R   P     N +   A +PT
Sbjct: 824  QVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTSTNGKVLAATAPT 883

Query: 96   P------KQASATTPGHESPRETRAQGPAGQEADGPRRT---LQVDSRTQRSGRS----P 142
            P         SA  P  +S    +A  P G     P +    L   S + R G +    P
Sbjct: 884  PGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQPLP 943

Query: 143  SVSP------DRGSTPTSPYSVPQIAPLPSST---LCPICKTSDLTSTPSQ------PNF 187
             VSP        G+ P  P  + Q+ P+P ST   L P    + L    SQ      P+ 
Sbjct: 944  LVSPPFSVPVQNGAQP--PSKIIQLTPVPVSTPSGLVPPLSPATLPGPTSQPQKVLLPSS 1001

Query: 188  NTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPAL 247
               T   +   +      +P  +Q             ALG            Q L S   
Sbjct: 1002 TRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFTSLGPSGPAFVQPLLSAGQ 1061

Query: 248  SPAHSPAK---QPLGKPD-QERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVS 303
            +P  +P +    P+  P        PGGP        TA  +  P P  +A    + + S
Sbjct: 1062 APLLAPGQVGVSPVPSPQLPPACAAPGGP------VITAFYSGSPAPTSSA---PLAQPS 1112

Query: 304  PQPPQPTKPSTAEPRPPAG----EAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLT 359
              PP           PPA     + P   ATA PA          G              
Sbjct: 1113 QAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAG-------------- 1158

Query: 360  QASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGAR 419
             + T   V P+A      AP K    I    AS   G    G+   PGPAP    EPG  
Sbjct: 1159 -SMTYSLVAPKAQRPSPKAPQKVKAAI----ASIPVGSFEAGASGRPGPAPRQPLEPGPV 1213

Query: 420  MGPGS------------GPGALPKTGGTTSPKHGRAEHQAASKAAAK-PKTM 458
              P +             P  LP+T   T+         A  + +AK P+TM
Sbjct: 1214 REPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETM 1265



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 272/1238 (21%), Positives = 405/1238 (32%), Gaps = 245/1238 (19%)

Query: 1322 SFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTP 1381
            S + PTS   +GG             KET++     +  A+    S E+    +Q   + 
Sbjct: 279  SEAKPTSLGLAGGH------------KETRERSMSETGTAAAPGVSSELLSVAAQTLLSS 326

Query: 1382 ATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQT-EDLPQAPS 1440
             T A      G  R +       G   S  P + +HS  HS       SQ  ++L Q  S
Sbjct: 327  DTKAPGSSSCGAERLHTV-----GGPGSARPRAFSHSGVHSLDGGEVDSQALQELTQMVS 381

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGP-- 1498
            G A+    +  KP +     G    P    +  A+  PPL P+  S S   +   M    
Sbjct: 382  GPASY---SGPKPSTQYGAPGPFAAPGEGGALAATGRPPLLPTRASRSQRAASEDMTSDE 438

Query: 1499 -------------------------------RATAEFSTQTPSPAPASDMPRSPGAPTPS 1527
                                           R T   S  +    P  +  +  G    S
Sbjct: 439  ERMVICEEEGDDDVIADDGFGTTDIDLKCKERVTDSESGDSSGEDPEGN--KGFGRKVFS 496

Query: 1528 PMVAQG--------TQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTS 1579
            P++              P  P  P + + +    AP       S ++S      ASA+TS
Sbjct: 497  PVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAP-------SSSASSPASSSASAATS 549

Query: 1580 PLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADG-PLALYGWGALPAE 1638
                    +    G   T  P    L P PPG  G P  PS      P+    +     E
Sbjct: 550  FSLGSGTFKAQESGQGSTAGP----LRPPPPGAGG-PATPSKATRFLPMDPATFRRKRPE 604

Query: 1639 NISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGL 1698
            ++        PG S +   P   G  +  L   + P        G  + S    +  YG 
Sbjct: 605  SVGGLE---PPGPSVIAAPPSGGGNILQTL--VLPPNKEEQEGGGARVPSAPAPSLAYGA 659

Query: 1699 ALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSR 1758
               P+    +T V  +V              ++  + +AS  F    +      D   +R
Sbjct: 660  PAAPLSRPAATMVTNVV-----------RPVSSTPVPIASKPFPTSGRAEASPNDTAGAR 708

Query: 1759 LDFGQG----GGSPVCLAQV---KQVEQAVQTAPYR-SGPR-GRPREAKFARYNL----P 1805
             + G G    GGSP+ ++ V   K+   A   AP+  +GP  G   +A     NL    P
Sbjct: 709  TEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTP 768

Query: 1806 NQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVV 1865
               AP       I Q   A   G   G     G+ P+   P  +     PGA        
Sbjct: 769  GYGAPAPPAVQFIAQ--GAPGGGTTAGSGAGAGSGPNGPVPLGILQ---PGAL------- 816

Query: 1866 QMGEGTAGTVTTL------LPEE------PAGALDLTGMRPESQLACCDMVYKLPFGSSC 1913
                G AG +T +      LP++      PA A       P        + + LP G+S 
Sbjct: 817  ----GKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIRFTLPPGTST 872

Query: 1914 TGTF----HPAPSVPEKSMADAAPP--GQSSSPFYGPRDPEPPEPPTYRAQGVVGPGPHE 1967
             G       P P +P      +APP   QS SP   P       PP   AQ         
Sbjct: 873  NGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAP-------PPGGSAQL-------- 917

Query: 1968 EQRPYPQGLPGRLYSSMSDTNLAE--AGLNYHAQRIGQLFQGPGRDSAMDLSSLKHSYSL 2025
                    LPG++   ++  +++    G       +   F  P ++ A   S +     +
Sbjct: 918  --------LPGKVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPV 969

Query: 2026 GFADGRYLGQGLQYGSVTDLRHPTDLLAHPLPMRRYSSVSNIYSDHRYGPRGDAVGFQEA 2085
              +    L   L   S   L  PT   + P  +   SS    Y     G     +G   A
Sbjct: 970  PVSTPSGLVPPL---SPATLPGPT---SQPQKVLLPSSTRITYVQSA-GGHALPLGTSPA 1022

Query: 2086 SLAQYSATTAREISRMCAALNSMDQYGGRHGSGGGGPDLVQYQPQHGPGLSAPQSLVPLR 2145
            S    + T+    S +     S+         G  GP  VQ      P LSA Q+ + L 
Sbjct: 1023 SSQAGTVTSYGPTSSVALGFTSL---------GPSGPAFVQ------PLLSAGQAPL-LA 1066

Query: 2146 PGLLGNPTFPEGHPSPGNLAQYGPAA----GQGTAVRQLLPSTATVRAADGMIYS--TIN 2199
            PG +G    P     P   A  GP          A     P     +A   ++Y+  T  
Sbjct: 1067 PGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATST 1126

Query: 2200 TPIAATL-------PITTQPA-----------SVLRPMVRGGMYRPY------ASGGITA 2235
            TP AAT+       P T  PA           S+   +V     RP           I +
Sbjct: 1127 TPPAATILPKGPPAPATATPAPTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIAS 1186

Query: 2236 VPLTSL----TRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPV-YLGKPAAAKA 2290
            +P+ S     +  P  APR PL P  +    AP         PPA  P+     P A  +
Sbjct: 1187 IPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSS 1246

Query: 2291 PGAGGPSRPEMPVGAAREEPLPTTTPAAIK-------------EAAGAPAPAPLAGQKPP 2337
            P    P+  E    A   E + +  P++               E    P+PAP     P 
Sbjct: 1247 PPLPPPA--EERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPG 1304

Query: 2338 ADAAPGGGSGALSRPGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERE 2397
              +    G  A   P  E++EA+   ++ K +   L+   + V+   L ++  +E     
Sbjct: 1305 GSSESSSGRAAGDTP--ERKEAAGTGKKVKVRPPPLKKTFDSVDNRVLSEVDFEERF--- 1359

Query: 2398 RVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQ 2435
              EL   R EE +L    LQ L T    +L   +++R+
Sbjct: 1360 -AELPEFRPEE-VLPSPTLQSLATSPRAILGSYRKKRK 1395



 Score = 58.5 bits (140), Expect = 1e-07
 Identities = 105/431 (24%), Positives = 149/431 (34%), Gaps = 84/431 (19%)

Query: 302 VSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQA 361
           + P+PP P  P  A  +   G AP+ SA++ PA   A+  T   L    F    S   Q 
Sbjct: 510 LDPEPPGPPDPPVAFGKG-YGSAPSSSASS-PASSSASAATSFSLGSGTFKAQES--GQG 565

Query: 362 STLMSVQPEADTQGQPA-PSKGTPKIVFNDAS-KEAGPKPLGSGPGPGPAPGAKTEPGAR 419
           ST   ++P     G PA PSK T  +  + A+ +   P+ +G    PGP+  A       
Sbjct: 566 STAGPLRPPPPGAGGPATPSKATRFLPMDPATFRRKRPESVGGLEPPGPSVIA------- 618

Query: 420 MGPGSGPGALPKT------------GGTTSPKHGRAEHQAASKAA--AKPKTMPKERAIC 465
             P SG G + +T            GG   P          + AA  ++P        + 
Sbjct: 619 -APPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVR 677

Query: 466 PLCQAELNVGSK-------SPANYNTCTTCRLQVC---------------------NLCG 497
           P+    + + SK       + A+ N     R ++                      +   
Sbjct: 678 PVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAA 737

Query: 498 FNPTPHLVEKTEWLCLN---CQTKRLLEGSLGEPTPLPPPT---SQQPPVGAPHRASGTS 551
            +P PHLV       +         LL G+ G   P PP     +Q  P G     SG  
Sbjct: 738 TSPAPHLVAGPLLGTVGKAPATVTNLLVGTPGYGAPAPPAVQFIAQGAPGGGTTAGSGAG 797

Query: 552 ---------PLKQKGPQGLGQPSGP------LPAKASPLSTKASPLPSKASPQAKPLRAS 596
                    PL    P  LG+  G       LP     L    +P P+  +  A P   S
Sbjct: 798 AGSGPNGPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAP---S 854

Query: 597 EPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAP 656
            P+ T S     +  +P       K    T PTP  P ++S      P    V  V   P
Sbjct: 855 GPAPTTSI----RFTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQSVSPVQAPP 910

Query: 657 KGGEAEDLVGK 667
            GG A+ L GK
Sbjct: 911 PGGSAQLLPGK 921



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 204/914 (22%), Positives = 292/914 (31%), Gaps = 171/914 (18%)

Query: 1122 SCSEYSPSPSLDSEAEA--LDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGR 1179
            S S  SP+ S  S A +  L  G  +  +SG         S   P   P      P +G 
Sbjct: 533  SSSASSPASSSASAATSFSLGSGTFKAQESGQG-------STAGPLRPPP-----PGAGG 580

Query: 1180 PLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQ------DTT 1233
            P   ++      M  A   +++     G   P  GPS    P   G    Q      +  
Sbjct: 581  PATPSKATRFLPMDPATFRRKRPESVGGLEPP--GPSVIAAPPSGGGNILQTLVLPPNKE 638

Query: 1234 DREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRM-RQASSRDLAFAEDKKKEKQFLN 1292
            ++E G A  P+A     + GA         +  +  + R  SS  +  A      K F  
Sbjct: 639  EQEGGGARVPSAPAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIAS-----KPFPT 693

Query: 1293 AESAYMDPMKQNGGPLTPGT-SPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQ 1351
            +  A   P    G     GT S     +P+  S   S   S     P   +         
Sbjct: 694  SGRAEASPNDTAGARTEMGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVA------- 746

Query: 1352 DPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPS 1411
             PL      A  +  +  +G P   G G PA  AV     G P G  T  S AG+   P+
Sbjct: 747  GPLLGTVGKAPATVTNLLVGTP---GYGAPAPPAVQFIAQGAPGGGTTAGSGAGAGSGPN 803

Query: 1412 ---------PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAARE----------- 1451
                     P +   + G +       +  + L  AP+   A G  A             
Sbjct: 804  GPVPLGILQPGALGKAGGITQVQYILPTLPQQLQVAPAPAPAPGTKAAAPSGPAPTTSIR 863

Query: 1452 ---KPLSASDGE---GGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFS 1505
                P ++++G+      P P         S+PP  P + S SP  +P   G        
Sbjct: 864  FTLPPGTSTNGKVLAATAPTPGIPILQSVPSAPP--PKAQSVSPVQAPPPGGSAQLLPGK 921

Query: 1506 TQTPSPAPASDMPRSPGAPTPSPMVA--------QGTQTPHR--PSTPRLVWQESSQEAP 1555
               P  AP+  + R  GA  P P+V+         G Q P +    TP  V   S    P
Sbjct: 922  VLVPLAAPSMSV-RGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPP 980

Query: 1556 FMVITLASDAS--------SQTRMVH---ASASTSPL-CSPTETQP-TTHGYSQTTPPSV 1602
                TL    S        S TR+ +   A     PL  SP  +Q  T   Y  T+  ++
Sbjct: 981  LSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVAL 1040

Query: 1603 SQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPG 1662
                  P GP     + SAG   PL   G             +S VP + ++ P    PG
Sbjct: 1041 GFTSLGPSGPAFVQPLLSAG-QAPLLAPG----------QVGVSPVP-SPQLPPACAAPG 1088

Query: 1663 TAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQE 1722
              V+    +  P P   +   +   S A  +  Y +A         T+  P    +  + 
Sbjct: 1089 GPVITAFYSGSPAP--TSSAPLAQPSQAPPSLVYTVA---------TSTTPPAATILPKG 1137

Query: 1723 HTFLATATTVSITMASSVFMAQQKQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQ 1782
                ATAT    +   S         +V   P   R        SP    +VK    ++ 
Sbjct: 1138 PPAPATATPAPTSPFPSATAGSMTYSLV--APKAQR-------PSPKAPQKVKAAIASIP 1188

Query: 1783 TAPYRSGPRGRPREAKFARYNLPNQVAPLARRDVLITQMGTAQSIGLKPGPVPEPGAEPH 1842
               + +G  GRP                           G A    L+PGPV EP     
Sbjct: 1189 VGSFEAGASGRP---------------------------GPAPRQPLEPGPVREP----- 1216

Query: 1843 RATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLTGMRPE---SQLA 1899
             A  +EL     P A  P      + E    T  +  P  P      +   PE   S+  
Sbjct: 1217 TAPESELEGQPTPPAPPP------LPETWTPTARSSPPLPPPAEERTSAKGPETMASKFP 1270

Query: 1900 CCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRDPEPPEPPTYRAQG 1959
                 +++P G        P P+ P  + A A  PG SS    G    + PE      + 
Sbjct: 1271 SSSSDWRVP-GQGLENRGEP-PTPPSPAPAPAVAPGGSSESSSGRAAGDTPE-----RKE 1323

Query: 1960 VVGPGPHEEQRPYP 1973
              G G   + RP P
Sbjct: 1324 AAGTGKKVKVRPPP 1337



 Score = 52.4 bits (124), Expect = 9e-06
 Identities = 152/680 (22%), Positives = 218/680 (32%), Gaps = 125/680 (18%)

Query: 14   GPLPPGGAGPGPGPGPGPGAGKPPSAP-------AGGGQLPAAGAARSTAVPPVPGPGPG 66
            G +PP      PGP   P     PS+        AGG  LP   +  S+    V   GP 
Sbjct: 976  GLVPPLSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPT 1035

Query: 67   PGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHE--SPRETRAQGPAGQEADG 124
                 G  S    L P  P   Q   S    QA    PG    SP  +    PA     G
Sbjct: 1036 SSVALGFTS----LGPSGPAFVQPLLSAG--QAPLLAPGQVGVSPVPSPQLPPACAAPGG 1089

Query: 125  PRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ 184
            P  T         +  +P   P + + P+  Y+V      P++T+ P    +  T+TP+ 
Sbjct: 1090 PVITAFYSGSPAPTSSAPLAQPSQ-APPSLVYTVATSTTPPAATILPKGPPAPATATPAP 1148

Query: 185  PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHS 244
             +                  P P  T           M  +L       P  K+ Q++ +
Sbjct: 1149 TS------------------PFPSATAGS--------MTYSLVAPKAQRPSPKAPQKVKA 1182

Query: 245  PALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSP 304
                     A  P+G  +   S  PG P P        R    PGP +    PE   +  
Sbjct: 1183 AI-------ASIPVGSFEAGASGRPG-PAP--------RQPLEPGPVREPTAPE-SELEG 1225

Query: 305  QPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTL 364
            QP  P  P    P P      A+S+  +P    A E+T                T AS  
Sbjct: 1226 QPTPPAPP----PLPETWTPTARSSPPLPPP--AEERTS----------AKGPETMASKF 1269

Query: 365  MSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTE--------- 415
             S   +    GQ   ++G P            P P    P P  APG  +E         
Sbjct: 1270 PSSSSDWRVPGQGLENRGEP------------PTPPSPAPAPAVAPGGSSESSSGRAAGD 1317

Query: 416  -PGARMGPGSG------PGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLC 468
             P  +   G+G      P  L KT  +   +   +E     + A  P+  P+E    P  
Sbjct: 1318 TPERKEAAGTGKKVKVRPPPLKKTFDSVDNRV-LSEVDFEERFAELPEFRPEEVLPSPTL 1376

Query: 469  QAELN-----VGSKSPANYN-----------TCTTCRLQVCNLCGFNP-TPHLVEKTEWL 511
            Q+        +GS      N           T    +++  + C   P TP   +    +
Sbjct: 1377 QSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSSCSSEPNTPKSAKCEGDI 1436

Query: 512  CLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAK 571
                +T    E  LGE      P S         RA      +  G     Q +    A+
Sbjct: 1437 FTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRALVMQLFQDHGFFPSAQATAAFQAR 1496

Query: 572  ASPLSTKASPLPSKASP-QAKPLRASEPSKTPSSVQEKKTRVP---TKAEPMPKPPPETT 627
             + +      L  K    + K ++A+ P++ P   +      P   T A P P P P   
Sbjct: 1497 YADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGG 1556

Query: 628  PTPATPKVKSGVRRAEPATP 647
            P P +P   SG  +A P  P
Sbjct: 1557 PDPTSPSSDSGTAQAAPPLP 1576



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 76/320 (23%), Positives = 104/320 (32%), Gaps = 77/320 (24%)

Query: 3654 SGRHTGEEP------GRRAAKPHARDLGRHEARP-HSQPSSAPAMPKKGQPGYPSSAEYS 3706
            SG  +GE+P      GR+   P  R    H   P   +P   P  P     GY S+   S
Sbjct: 476  SGDSSGEDPEGNKGFGRKVFSPVIRSSFTHCRPPLDPEPPGPPDPPVAFGKGYGSAPSSS 535

Query: 3707 QPSRASSAYHHASDSKKGS---RQAHSGPAALQSKAEP---------------------- 3741
              S ASS+   A+    GS   +   SG  +      P                      
Sbjct: 536  ASSPASSSASAATSFSLGSGTFKAQESGQGSTAGPLRPPPPGAGGPATPSKATRFLPMDP 595

Query: 3742 ----QAQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS-----RQPQTQQQQQGLGLQPPQQ 3792
                + +P+  G    PGP    +P     PSG  +       P  +++Q+G G + P  
Sbjct: 596  ATFRRKRPESVGGLEPPGPSVIAAP-----PSGGGNILQTLVLPPNKEEQEGGGARVPSA 650

Query: 3793 ALTQARLQQQSQPTTRGSA--------PAASQP---AGKPQPGPSTA-TGPQPAGPPRAE 3840
                      + P +R +A        P +S P   A KP P    A   P      R E
Sbjct: 651  PAPSLAYGAPAAPLSRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTE 710

Query: 3841 QTNGSKGTAKAP--------QQGRAPQAQPAPG--PGPAGVKAGARPG-------GTPGA 3883
               GS+    +P         +  A    PAP    GP     G  P        GTPG 
Sbjct: 711  MGTGSRVPGGSPLGVSLVYSDKKSAAATSPAPHLVAGPLLGTVGKAPATVTNLLVGTPG- 769

Query: 3884 PAGQPGADGESVFSKILPGG 3903
              G P        ++  PGG
Sbjct: 770  -YGAPAPPAVQFIAQGAPGG 788



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 78/362 (21%), Positives = 115/362 (31%), Gaps = 62/362 (17%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            PLPP         GP   A K PS+ +   ++P  G       P  P P P P   PG  
Sbjct: 1248 PLPPPAEERTSAKGPETMASKFPSS-SSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGS 1306

Query: 75   STSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEA--DGPRRTLQVD 132
            S S          + RAA  TP++  A   G    ++ + + P  ++       R L   
Sbjct: 1307 SES---------SSGRAAGDTPERKEAAGTG----KKVKVRPPPLKKTFDSVDNRVLSEV 1353

Query: 133  SRTQRSGRSPSV-------SPDRGSTPTSPYSV-----------PQIAPLPSSTLCPICK 174
               +R    P         SP   S  TSP ++             +   P     P  K
Sbjct: 1354 DFEERFAELPEFRPEEVLPSPTLQSLATSPRAILGSYRKKRKNSTDLDSAPEDPTSPKRK 1413

Query: 175  TSDLTSTPSQPNFNTCTQCHNKV--CNQCGFNPNPHLTQVK------EWLCLNCQMQRAL 226
                +S  S+PN     +C   +   ++ G      L +++        L      +RAL
Sbjct: 1414 MRRRSSCSSEPNTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDKVPYSSLRRTLDQRRAL 1473

Query: 227  GMDM-----------TTAP---------RSKSQQQLHSPALSPAHSPAKQPLGKPDQERS 266
             M +            TA           SK   QL    +      A  P  +P    +
Sbjct: 1474 VMQLFQDHGFFPSAQATAAFQARYADIFPSKVCLQLKIREVRQKIMQAATPTEQPPGAEA 1533

Query: 267  RGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPA 326
              P  P  G+  A     +   GP   +   + G     PP P  P +   +P    AP 
Sbjct: 1534 PLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWEGAPQ 1593

Query: 327  KS 328
             S
Sbjct: 1594 PS 1595



 Score = 42.0 bits (97), Expect = 0.012
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 12/72 (16%)

Query: 17   PPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPG-PG--------- 66
            PP G    P P P P  G  P++P+       A AA     PP  GPG PG         
Sbjct: 1539 PPTGTAAAPAPTPSPAGGPDPTSPSSDS--GTAQAAPPLPPPPESGPGQPGWEGAPQPSP 1596

Query: 67   PGPGPGPGSTSR 78
            P PGP   +T R
Sbjct: 1597 PPPGPSTAATGR 1608



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 31/105 (29%), Positives = 42/105 (40%), Gaps = 15/105 (14%)

Query: 3785 LGLQPPQQALTQARLQQQSQPTTRGSAPAA--SQPAGKPQPGPSTATGPQPAGPPRAEQT 3842
            L ++  +Q + QA    +  P      P    +  A  P P PS A GP P  P      
Sbjct: 1509 LKIREVRQKIMQAATPTEQPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSP------ 1562

Query: 3843 NGSKGTAKAPQQGRAPQAQPAP--GPGPAGVKAGARPGGTPGAPA 3885
            +   GTA+A     AP   P P  GPG  G +   +P   P  P+
Sbjct: 1563 SSDSGTAQA-----APPLPPPPESGPGQPGWEGAPQPSPPPPGPS 1602



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 107/457 (23%), Positives = 149/457 (32%), Gaps = 123/457 (26%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            T P G   +    AA   TP  P     P   PP  Q    S  P Q   P   A   PG
Sbjct: 865  TLPPGTSTNGKVLAATAPTPGIPILQSVPSAPPPKAQ----SVSPVQAPPPGGSAQLLPG 920

Query: 3086 PSTYP--APAFPPGASYPAEP--------GLPNQQAFRPTGHYAGQTPMP-TTQSTLFP- 3133
                P  AP+         +P         +P Q   +P       TP+P +T S L P 
Sbjct: 921  KVLVPLAAPSMSVRGGGAGQPLPLVSPPFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPP 980

Query: 3134 -VPADSRAPLQKPRQ-----------------------TSLADLEQKVPTNYEVIASPVV 3169
              PA    P  +P++                       TS A  +    T+Y   +S  +
Sbjct: 981  LSPATLPGPTSQPQKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVAL 1040

Query: 3170 PMSS-APSETSYSGPAVSSG----YEQGKV-------PEVPR--AGDRGSV-----SQSP 3210
              +S  PS  ++  P +S+G       G+V       P++P   A   G V     S SP
Sbjct: 1041 GFTSLGPSGPAFVQPLLSAGQAPLLAPGQVGVSPVPSPQLPPACAAPGGPVITAFYSGSP 1100

Query: 3211 APT----------YPSDSHYTSLEQNVPRNYVMIDDISELTKDSTS-------------- 3246
            APT           P    YT      P    ++         +T               
Sbjct: 1101 APTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPATATPAPTSPFPSATAGSM 1160

Query: 3247 ----TAPDSQRLEPLGP-----------------GSSGRPG---KEPGEPGVLDGPTLPC 3282
                 AP +QR  P  P                 G+SGRPG   ++P EPG +  PT P 
Sbjct: 1161 TYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPE 1220

Query: 3283 CYARGEEESE-----EDSYDPRGKGG--------HLRSMESNGRPASTHYYGDSDYR-HG 3328
                G+          +++ P  +             S +     AS      SD+R  G
Sbjct: 1221 SELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKFPSSSSDWRVPG 1280

Query: 3329 ARVEKYGPGPMGPK-HPSKSLAPAAISSKRSKHRKQG 3364
              +E  G  P  P   P+ ++AP   SS+ S  R  G
Sbjct: 1281 QGLENRGEPPTPPSPAPAPAVAPGG-SSESSSGRAAG 1316



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 54/233 (23%), Positives = 83/233 (35%), Gaps = 49/233 (21%)

Query: 3695 GQPGYPSSAEYSQPSRA--SSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQA 3752
            G P   SSA  +QPS+A  S  Y  A+ +        + PAA      P A         
Sbjct: 1098 GSPAPTSSAPLAQPSQAPPSLVYTVATST--------TPPAATILPKGPPAPATATPAPT 1149

Query: 3753 APGPQQSQSPSSRQIPSGAASR-QPQTQQQ-------------QQGLGLQP---PQQALT 3795
            +P P  +    +  + +  A R  P+  Q+             + G   +P   P+Q L 
Sbjct: 1150 SPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLE 1209

Query: 3796 QARLQQQSQPTTR-GSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG---------- 3844
               +++ + P +     P    P   P+    TA    P  PP  E+T+           
Sbjct: 1210 PGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAEERTSAKGPETMASKF 1269

Query: 3845 --SKGTAKAPQQGRA----PQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGAD 3891
              S    + P QG      P   P+P P PA       PGG+  + +G+   D
Sbjct: 1270 PSSSSDWRVPGQGLENRGEPPTPPSPAPAPA-----VAPGGSSESSSGRAAGD 1317



 Score = 39.3 bits (90), Expect = 0.078
 Identities = 35/103 (33%), Positives = 46/103 (44%), Gaps = 12/103 (11%)

Query: 3041 APATPSG---PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPG 3097
            AP+ P     P+  QQP   P A   S  S  P ++   AH+ P  PG +    P  PPG
Sbjct: 45   APSQPDPSVQPSEAQQPASHPVA---SNQSKEPAESAAVAHERP--PGGTGSADPERPPG 99

Query: 3098 ASYPAEPGLPNQQAFRPTGHY-AGQTPMPTTQSTLFPVPADSR 3139
            A+ P  PG P      P G   +G+ P PTT+      P + R
Sbjct: 100  ATCPESPG-PGPP--HPLGVVESGKGPPPTTEEEASGPPGEPR 139



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 53/201 (26%), Positives = 77/201 (38%), Gaps = 33/201 (16%)

Query: 3023 QGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPT 3082
            QG T  AG     P  A  PATPS  T     RF P  P         +  G        
Sbjct: 564  QGST--AGPLRPPPPGAGGPATPSKAT-----RFLPMDPATFRRKRPESVGGLEP----- 611

Query: 3083 YPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPL 3142
             PGPS   AP    G         PN++     G      P P   S  +  PA   APL
Sbjct: 612  -PGPSVIAAPPSGGGNILQTLVLPPNKEEQEGGGARVPSAPAP---SLAYGAPA---APL 664

Query: 3143 QKPRQTSLADLEQKVPTNYEVIASPVVPMS----SAPSETSYSGPAVSSGYEQGKVP--- 3195
             +P  T + ++ + V +    IAS   P S    ++P++T+ +   + +G    +VP   
Sbjct: 665  SRPAATMVTNVVRPVSSTPVPIASKPFPTSGRAEASPNDTAGARTEMGTG---SRVPGGS 721

Query: 3196 ----EVPRAGDRGSVSQSPAP 3212
                 +  +  + + + SPAP
Sbjct: 722  PLGVSLVYSDKKSAAATSPAP 742



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 52/180 (28%), Positives = 63/180 (35%), Gaps = 28/180 (15%)

Query: 3736 QSKAEPQAQPQLQGRQAAPG-PQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQAL 3794
            Q    P   PQL    AAPG P  +   S    P+ +A   P  Q  Q      PP    
Sbjct: 1069 QVGVSPVPSPQLPPACAAPGGPVITAFYSGSPAPTSSA---PLAQPSQA-----PPSLVY 1120

Query: 3795 TQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGP-PRAEQTNGSKGTAKAPQ 3853
            T A            + P A+    K  P P+TAT P P  P P A  T GS   +    
Sbjct: 1121 TVAT----------STTPPAATILPKGPPAPATAT-PAPTSPFPSA--TAGSMTYSLV-- 1165

Query: 3854 QGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVFSKILPGGAAEQAGKLTE 3913
               AP+AQ      P  VKA           AG  G  G +    + PG   E     +E
Sbjct: 1166 ---APKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGPAPRQPLEPGPVREPTAPESE 1222



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 5/99 (5%)

Query: 2244 VPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPV 2303
            VP +AP  P           P+  P+AS+   ++ P      A  + PG  G + PE P 
Sbjct: 41   VPFLAPSQPDPSVQPSEAQQPASHPVASN--QSKEPAESAAVAHERPPGGTGSADPERPP 98

Query: 2304 GAAREE---PLPTTTPAAIKEAAGAPAPAPLAGQKPPAD 2339
            GA   E   P P      ++   G P         PP +
Sbjct: 99   GATCPESPGPGPPHPLGVVESGKGPPPTTEEEASGPPGE 137



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 21/75 (28%), Positives = 25/75 (33%), Gaps = 2/75 (2%)

Query: 50   GAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAAS--PTPKQASATTPGHE 107
            GA     VPP  G    P P P P        P    G  +AA   P P ++    PG E
Sbjct: 1530 GAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQPGWE 1589

Query: 108  SPRETRAQGPAGQEA 122
               +     P    A
Sbjct: 1590 GAPQPSPPPPGPSTA 1604


>gi|116284392 mucin 2 precursor [Homo sapiens]
          Length = 5179

 Score = 76.6 bits (187), Expect = 4e-13
 Identities = 152/763 (19%), Positives = 230/763 (30%), Gaps = 86/763 (11%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 3590 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649

Query: 75   STSRRLDPKE-PLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 3650 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPT 3704

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 3705 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 3762

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 3763 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 3805

Query: 254  AKQPLGKPDQER-SRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 3859

Query: 313  STAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD 372
            +T  P       P  + T  P     T  T    T    G      T  +T  +V P   
Sbjct: 3860 TTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3913

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPG------------PGPAP-GAKTEPGAR 419
              G   P+  TP  +    +    P P G+               P P P G +T     
Sbjct: 3914 PTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970

Query: 420  MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSP 479
            +   +     P   GT +P                P T  +     P+        + +P
Sbjct: 3971 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTP 4029

Query: 480  ANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
                T TT  +         PTP   +      +   T           TP P PT  Q 
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTT---------VTPTPTPTGTQT 4080

Query: 540  PVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEP 598
            P   P   + T +P           P+G      +P++T  +      +P   P     P
Sbjct: 4081 PTTTPITTTTTVTPTPT--------PTGTQTPTTTPITTTTT-----VTPTPTPTGTQTP 4127

Query: 599  SKTPSSVQEKKTRVPTKAEPM-PKPPPETT-------PTPATPKVKSGVRRAEPATPVVK 650
            + TP +     T  PT      P   P TT       PTP   +  +        T    
Sbjct: 4128 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPT 4187

Query: 651  AVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDS 710
              P   + G        P ++  + +P   S T  +S   SS  +E T ++      ++ 
Sbjct: 4188 PTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEM 4247

Query: 711  AGVTGPHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGT 753
                 P  P+       G ++ P        P   ++  ++G+
Sbjct: 4248 TSTAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGS 4290



 Score = 75.9 bits (185), Expect = 8e-13
 Identities = 146/684 (21%), Positives = 207/684 (30%), Gaps = 93/684 (13%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPP----SAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPG 70
            P PP      P P P      PP    S P      P      S  +     P P   P 
Sbjct: 1399 PSPPTTT---PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPS 1455

Query: 71   PGPGST-----SRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGP 125
            P   +T     +    P     +    +P+P   + TTP    P  T    P       P
Sbjct: 1456 PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTP----PPTTTPSPPTTTPITPP 1511

Query: 126  RRTLQVDSRTQRS-GRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQ 184
              T  +   T  S   + + +P   +TP+ P + P   P  ++TL P       T+TPS 
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPP-------TTTPSP 1564

Query: 185  PNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHS 244
            P   T T             P+P  T       +            TT P   +      
Sbjct: 1565 PPTTTTTPPPTT-------TPSPPTTTTPSPPTITTTTP-----PPTTTPSPPTTTTTTP 1612

Query: 245  PALSPAHSPAKQPLGKPDQERSRGP-GGPQPGSRQAETARATSVPGPAQAAAP-PEVGRV 302
            P  +    P   P+  P    +  P   P P      T   T+ P P     P P +   
Sbjct: 1613 PPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTT 1672

Query: 303  SPQPP--QPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQ 360
            +  PP   P+ P T  P PP       S T  P+    T  T    T           + 
Sbjct: 1673 TTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTP---------SP 1723

Query: 361  ASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARM 420
              T M+      T   P  +  T       +     P P    P P  +P + T P    
Sbjct: 1724 PPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP-PTFSPFSTTTPTTPC 1782

Query: 421  GP--------GSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPK-------ERAIC 465
             P         SG     K GG T           A+  + +    P        +  +C
Sbjct: 1783 VPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANISCRATMYPDVPIGQLGQTVVC 1842

Query: 466  P-----LCQAE-LNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKR 519
                  +C+ E    G   P  +       +Q C  C   PT      TE       T  
Sbjct: 1843 DVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCE-CVTQPTTMTTTTTENPTPPTTTPI 1901

Query: 520  LLEGSLGEPTPLPPPTSQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTK 578
                ++   TP P PT  Q P   P   + T +P           P+G      +P++T 
Sbjct: 1902 TTTTTV---TPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTT 1950

Query: 579  ASPLPSKA-----SPQAKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPT 629
             +  P+       +P   P+  +    P+ TP+  Q   T  + T     P P P  T T
Sbjct: 1951 TTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2010

Query: 630  PATPKVKSGVRRAEPATPVVKAVP 653
            P T  + +        TP     P
Sbjct: 2011 PTTTPITTTTTVTPTPTPTGTQTP 2034



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 138/664 (20%), Positives = 201/664 (30%), Gaps = 82/664 (12%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 1911 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 1970

Query: 75   STSRRLDP-KEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 1971 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 2025

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 2026 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 2083

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 2084 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 2126

Query: 254  AKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 2127 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 2180

Query: 313  STAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD 372
            +T  P       P  + T  P     T  T    T    G      T  +T  +V P   
Sbjct: 2181 TTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2234

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTEPGAR 419
              G   P+  TP  +    +    P P G+               P P P G +T     
Sbjct: 2235 PTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291

Query: 420  MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSP 479
            +   +     P   GT +P                P T  +     P+        + +P
Sbjct: 2292 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTP 2350

Query: 480  ANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
                T TT  +         PTP   +      +   T           TP P PT  Q 
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPTGTQT 2401

Query: 540  PVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQAKPL 593
            P   P   + T +P           P+G      +P++T  +  P+       +P   P+
Sbjct: 2402 PTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2453

Query: 594  RAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVV 649
              +    P+ TP+  Q   T  + T     P P P  T TP T  + +        TP  
Sbjct: 2454 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 2513

Query: 650  KAVP 653
               P
Sbjct: 2514 TQTP 2517



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 138/664 (20%), Positives = 201/664 (30%), Gaps = 82/664 (12%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 2440 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499

Query: 75   STSRRLDP-KEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 2500 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 2554

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 2555 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 2612

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 2613 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 2655

Query: 254  AKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 2656 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 2709

Query: 313  STAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD 372
            +T  P       P  + T  P     T  T    T    G      T  +T  +V P   
Sbjct: 2710 TTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 2763

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTEPGAR 419
              G   P+  TP  +    +    P P G+               P P P G +T     
Sbjct: 2764 PTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820

Query: 420  MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSP 479
            +   +     P   GT +P                P T  +     P+        + +P
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTP 2879

Query: 480  ANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
                T TT  +         PTP   +      +   T           TP P PT  Q 
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPTGTQT 2930

Query: 540  PVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQAKPL 593
            P   P   + T +P           P+G      +P++T  +  P+       +P   P+
Sbjct: 2931 PTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982

Query: 594  RAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVV 649
              +    P+ TP+  Q   T  + T     P P P  T TP T  + +        TP  
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3042

Query: 650  KAVP 653
               P
Sbjct: 3043 TQTP 3046



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 138/664 (20%), Positives = 201/664 (30%), Gaps = 82/664 (12%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 2969 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028

Query: 75   STSRRLDP-KEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 3029 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 3083

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 3084 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 3141

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 3142 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 3184

Query: 254  AKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 3185 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 3238

Query: 313  STAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD 372
            +T  P       P  + T  P     T  T    T    G      T  +T  +V P   
Sbjct: 3239 TTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3292

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTEPGAR 419
              G   P+  TP  +    +    P P G+               P P P G +T     
Sbjct: 3293 PTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349

Query: 420  MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSP 479
            +   +     P   GT +P                P T  +     P+        + +P
Sbjct: 3350 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTP 3408

Query: 480  ANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
                T TT  +         PTP   +      +   T           TP P PT  Q 
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPTGTQT 3459

Query: 540  PVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQAKPL 593
            P   P   + T +P           P+G      +P++T  +  P+       +P   P+
Sbjct: 3460 PTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511

Query: 594  RAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVV 649
              +    P+ TP+  Q   T  + T     P P P  T TP T  + +        TP  
Sbjct: 3512 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 3571

Query: 650  KAVP 653
               P
Sbjct: 3572 TQTP 3575



 Score = 74.3 bits (181), Expect = 2e-12
 Identities = 138/664 (20%), Positives = 201/664 (30%), Gaps = 82/664 (12%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 3498 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557

Query: 75   STSRRLDP-KEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 3558 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPT 3612

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 3613 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 3670

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 3671 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 3713

Query: 254  AKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 3714 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 3767

Query: 313  STAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEAD 372
            +T  P       P  + T  P     T  T    T    G      T  +T  +V P   
Sbjct: 3768 TTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPT 3821

Query: 373  TQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTEPGAR 419
              G   P+  TP  +    +    P P G+               P P P G +T     
Sbjct: 3822 PTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878

Query: 420  MGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSP 479
            +   +     P   GT +P                P T  +     P+        + +P
Sbjct: 3879 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTP 3937

Query: 480  ANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQP 539
                T TT  +         PTP   +      +   T           TP P PT  Q 
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPTGTQT 3988

Query: 540  PVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQAKPL 593
            P   P   + T +P           P+G      +P++T  +  P+       +P   P+
Sbjct: 3989 PTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040

Query: 594  RAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVV 649
              +    P+ TP+  Q   T  + T     P P P  T TP T  + +        TP  
Sbjct: 4041 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4100

Query: 650  KAVP 653
               P
Sbjct: 4101 TQTP 4104



 Score = 72.4 bits (176), Expect = 8e-12
 Identities = 129/598 (21%), Positives = 182/598 (30%), Gaps = 120/598 (20%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 3912 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971

Query: 75   STSRRLDPKE-PLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 3972 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPT 4026

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQC 193
             T    ++P+ +P   +T  +P   P     P++T  PI  T+ +T TP+     T T  
Sbjct: 4027 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTT 4084

Query: 194  HNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSP 253
                       P P  TQ                   TT P + +     +P  +   +P
Sbjct: 4085 PITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTGTQTP 4127

Query: 254  AKQPLGKPDQER-SRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKP 312
               P+        +  P G Q  +    T   T  P       P   G  +P     T  
Sbjct: 4128 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTT 4181

Query: 313  STAEPRP-PAGEA---PAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
            +T  P P P G     P  ++TA  A L  +    E  T +     +S LT+++TL+S  
Sbjct: 4182 TTVTPTPTPTGTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTL 4241

Query: 369  PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGA 428
            P A      AP            S    P     G    P P   T P     PG+ P  
Sbjct: 4242 PPAIEMTSTAP-----------PSTPTAPTTTSGGHTLSPPPSTTTSP-----PGT-PTR 4284

Query: 429  LPKTGGTTSPKHGRAEHQAASKAAAKP--------------KTMPKERAICPLCQAELNV 474
               TG +++P     +    S     P              +  P    IC +       
Sbjct: 4285 GTTTGSSSAPTPSTVQTTTTSAWTPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYA 4344

Query: 475  GSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPP 534
              +   N     TC    C+L         +E   W C                TP P P
Sbjct: 4345 PGEEVYNGTYGDTCYFVNCSL------SCTLEFYNWSC--------------PSTPSPTP 4384

Query: 535  TSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKP 592
            T                                 P+K++P  +K S  PSK +P  KP
Sbjct: 4385 T---------------------------------PSKSTPTPSKPSSTPSKPTPGTKP 4409



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 133/643 (20%), Positives = 196/643 (30%), Gaps = 82/643 (12%)

Query: 36   PPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDP-KEPLGNQRAASP 94
            P   P G           +T V P P P     P   P +T+  + P   P G Q   +P
Sbjct: 1909 PTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TP 1965

Query: 95   TPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTS 154
            T    + TT    +P  T  Q P          T    + T    ++P+ +P   +T  +
Sbjct: 1966 TTTPITTTTTVTPTPTPTGTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2023

Query: 155  PYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKE 214
            P   P     P++T  PI  T+ +T TP+     T T             P P  TQ   
Sbjct: 2024 PTPTPTGTQTPTTT--PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP- 2080

Query: 215  WLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQ-ERSRGPGGPQ 273
                            TT P + +     +P  +   +P   P+        +  P G Q
Sbjct: 2081 ----------------TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2124

Query: 274  PGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVP 333
              +    T   T  P       P   G  +P     T  +T  P       P  + T  P
Sbjct: 2125 TPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTP 2172

Query: 334  AGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASK 393
                 T  T    T    G      T  +T  +V P     G   P+  TP  +    + 
Sbjct: 2173 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TP--ITTTTTV 2229

Query: 394  EAGPKPLGSGP------------GPGPAP-GAKTEPGARMGPGSGPGALPKTGGTTSPKH 440
               P P G+               P P P G +T     +   +     P   GT +P  
Sbjct: 2230 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT 2289

Query: 441  GRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP 500
                          P T  +     P+        + +P    T TT  +         P
Sbjct: 2290 TPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2348

Query: 501  TPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT-SPLKQKGPQ 559
            TP   +      +   T           TP P PT  Q P   P   + T +P       
Sbjct: 2349 TPTGTQTPTTTPITTTT---------TVTPTPTPTGTQTPTTTPITTTTTVTPTP----- 2394

Query: 560  GLGQPSGPLPAKASPLSTKASPLPSKA-----SPQAKPLRAS---EPSKTPSSVQEKKTR 611
                P+G      +P++T  +  P+       +P   P+  +    P+ TP+  Q   T 
Sbjct: 2395 ---TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2451

Query: 612  -VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVP 653
             + T     P P P  T TP T  + +        TP     P
Sbjct: 2452 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2494



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 146/711 (20%), Positives = 224/711 (31%), Gaps = 96/711 (13%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3740 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3798

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3799 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3853

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3854 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3909

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3910 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3959

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3960 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 4018 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 4076

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 4077 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 4131

Query: 1714 LV-----------INLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPY-QSRLDF 1761
            +                    T + T TTV+ T   +        P+        +    
Sbjct: 4132 ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 4191

Query: 1762 GQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPR-------EAKFARYNLPNQVAPLARR 1814
            G   G P   +     E      P  S      R       E+      LP  +   +  
Sbjct: 4192 GTQTGPPTHTSTAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTA 4251

Query: 1815 DVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGT 1874
                    T  S G    P P     P   TP    +     A  P TV       T+  
Sbjct: 4252 PPSTPTAPTTTSGGHTLSPPPSTTTSP-PGTPTRGTTTGSSSAPTPSTVQTTT---TSAW 4307

Query: 1875 VTTLLPEEPAGALDLTGMR--PESQLACC----------DMVYKLPFGS----------- 1911
              T  P      +  TG+R  P S L CC          + VY   +G            
Sbjct: 4308 TPTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGDTCYFVNCSLSC 4367

Query: 1912 -------SCTGTFHPAPSVPEKSMADAAPPGQSSSPFYGPRDPEPP--EPP 1953
                   SC  T  P P+  + +   + P    S P  G + PE P  +PP
Sbjct: 4368 TLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFDPP 4418



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 135/658 (20%), Positives = 195/658 (29%), Gaps = 108/658 (16%)

Query: 38   SAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPK 97
            + P+     P+     +T +PP   P P       P  T+    P  P+       PT  
Sbjct: 1397 TTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTT---PSPPITTTTTPPPT-- 1451

Query: 98   QASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYS 157
                TTP    P  T    P       P  T    + T     + + +P   +TP+ P +
Sbjct: 1452 ----TTPS--PPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT 1505

Query: 158  VPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLC 217
             P   P  ++TL P       T+TPS P   T T             P P  T       
Sbjct: 1506 TPITPPASTTTLPP-------TTTPSPPTTTTTT-------------PPPTTTPSPPTTT 1545

Query: 218  LNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSR 277
                      +  TT P          P  +    P       P    +     P P + 
Sbjct: 1546 PITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTT----PPPTTT 1601

Query: 278  QAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLG 337
             +     T+ P P    +PP    ++P     T P T  P PP         T  P+   
Sbjct: 1602 PSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT 1661

Query: 338  ATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGP 397
             T  +    T           T   T     P   T   P  +  TP      +S     
Sbjct: 1662 TTTPSPPITT---------TTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTT 1712

Query: 398  KPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKT 457
                S   P P P   T P     P       P T  TT P                P T
Sbjct: 1713 TTPSSTTTPSPPPTTMTTPSPTTTPSP-----PTTTMTTLP----------------PTT 1751

Query: 458  MPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGF----NPTPHL----VEKTE 509
                    PL    +   + SP +  T TT  + +CN  G+     P  H      E   
Sbjct: 1752 TSSPLTTTPL-PPSITPPTFSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIG 1810

Query: 510  WLC-------LNCQTKRLLE---GSLGE------PTPLPPPTSQQPPVGA-PHRASGTSP 552
             +C       ++C+     +   G LG+         L      Q P G  P        
Sbjct: 1811 DVCGPGWAANISCRATMYPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYE 1870

Query: 553  LKQKGPQGLGQPS--------GPLPAKASPLSTKASPLPSKA-----SPQAKPLRAS--- 596
            +  +  + + QP+         P P   +P++T  +  P+       +P   P+  +   
Sbjct: 1871 INVQCCECVTQPTTMTTTTTENPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 1930

Query: 597  EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVP 653
             P+ TP+  Q   T  + T     P P P  T TP T  + +        TP     P
Sbjct: 1931 TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 1988



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 130/625 (20%), Positives = 193/625 (30%), Gaps = 82/625 (13%)

Query: 54   STAVPPVPGPGPGPGPGPGPGSTSRRLDP-KEPLGNQRAASPTPKQASATTPGHESPRET 112
            +T V P P P     P   P +T+  + P   P G Q   +PT    + TT    +P  T
Sbjct: 1904 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPT 1960

Query: 113  RAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPI 172
              Q P          T    + T    ++P+ +P   +T  +P   P     P++T  PI
Sbjct: 1961 GTQTPTTTPI--TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT--PI 2016

Query: 173  CKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTT 232
              T+ +T TP+     T T             P P  TQ                   TT
Sbjct: 2017 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP-----------------TT 2059

Query: 233  APRSKSQQQLHSPALSPAHSPAKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPA 291
             P + +     +P  +   +P   P+        +  P G Q  +    T   T  P   
Sbjct: 2060 TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP--- 2116

Query: 292  QAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLF 351
                P   G  +P     T  +T  P       P  + T  P     T  T    T    
Sbjct: 2117 ---TPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPT 2167

Query: 352  GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------- 404
            G      T  +T  +V P     G   P+  TP  +    +    P P G+         
Sbjct: 2168 GTQTPTTTPITTTTTVTPTPTPTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPIT 2224

Query: 405  -----GPGPAP-GAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
                  P P P G +T     +   +     P   GT +P                P T 
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TG 2283

Query: 459  PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
             +     P+        + +P    T TT  +         PTP   +      +   T 
Sbjct: 2284 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT- 2342

Query: 519  RLLEGSLGEPTPLPPPTSQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLST 577
                      TP P PT  Q P   P   + T +P           P+G      +P++T
Sbjct: 2343 --------TVTPTPTPTGTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITT 2386

Query: 578  KASPLPSKA-----SPQAKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTP 628
              +  P+       +P   P+  +    P+ TP+  Q   T  + T     P P P  T 
Sbjct: 2387 TTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQ 2446

Query: 629  TPATPKVKSGVRRAEPATPVVKAVP 653
            TP T  + +        TP     P
Sbjct: 2447 TPTTTPITTTTTVTPTPTPTGTQTP 2471



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 138/668 (20%), Positives = 200/668 (29%), Gaps = 90/668 (13%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 2371 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 75   STSRRLDPKE-PLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 2431 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPT 2485

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSS----TLCPICKTSDLTSTPSQPNFNT 189
             T    ++P+ +P   +T  +P       P P+     T  PI  T+ +T TP+     T
Sbjct: 2486 PTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 2539

Query: 190  CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249
             T             P P  TQ                   TT P + +     +P  + 
Sbjct: 2540 PTTTPITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTG 2582

Query: 250  AHSPAKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQ 308
              +P   P+        +  P G Q  +    T   T  P       P   G  +P    
Sbjct: 2583 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP 2636

Query: 309  PTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
             T  +T  P       P  + T  P     T  T    T    G      T  +T  +V 
Sbjct: 2637 ITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2690

Query: 369  PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTE 415
            P     G   P+  TP  +    +    P P G+               P P P G +T 
Sbjct: 2691 PTPTPTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2747

Query: 416  PGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG 475
                +   +     P   GT +P                P T  +     P+        
Sbjct: 2748 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2806

Query: 476  SKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPT 535
            + +P    T TT  +         PTP   +      +   T           TP P PT
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPT 2857

Query: 536  SQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQ 589
              Q P   P   + T +P           P+G      +P++T  +  P+       +P 
Sbjct: 2858 GTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2909

Query: 590  AKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
              P+  +    P+ TP+  Q   T  + T     P P P  T TP T  + +        
Sbjct: 2910 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2969

Query: 646  TPVVKAVP 653
            TP     P
Sbjct: 2970 TPTGTQTP 2977



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 138/668 (20%), Positives = 200/668 (29%), Gaps = 90/668 (13%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 2900 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959

Query: 75   STSRRLDPKE-PLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 2960 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPT 3014

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSS----TLCPICKTSDLTSTPSQPNFNT 189
             T    ++P+ +P   +T  +P       P P+     T  PI  T+ +T TP+     T
Sbjct: 3015 PTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3068

Query: 190  CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249
             T             P P  TQ                   TT P + +     +P  + 
Sbjct: 3069 PTTTPITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTG 3111

Query: 250  AHSPAKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQ 308
              +P   P+        +  P G Q  +    T   T  P       P   G  +P    
Sbjct: 3112 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP 3165

Query: 309  PTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
             T  +T  P       P  + T  P     T  T    T    G      T  +T  +V 
Sbjct: 3166 ITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 369  PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTE 415
            P     G   P+  TP  +    +    P P G+               P P P G +T 
Sbjct: 3220 PTPTPTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3276

Query: 416  PGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG 475
                +   +     P   GT +P                P T  +     P+        
Sbjct: 3277 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3335

Query: 476  SKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPT 535
            + +P    T TT  +         PTP   +      +   T           TP P PT
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPT 3386

Query: 536  SQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQ 589
              Q P   P   + T +P           P+G      +P++T  +  P+       +P 
Sbjct: 3387 GTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3438

Query: 590  AKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
              P+  +    P+ TP+  Q   T  + T     P P P  T TP T  + +        
Sbjct: 3439 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 3498

Query: 646  TPVVKAVP 653
            TP     P
Sbjct: 3499 TPTGTQTP 3506



 Score = 69.3 bits (168), Expect = 7e-11
 Identities = 138/668 (20%), Positives = 200/668 (29%), Gaps = 90/668 (13%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P G   P   P        P   P G           +T V P P P     P   P 
Sbjct: 3429 PTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488

Query: 75   STSRRLDPKE-PLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDS 133
            +T+  + P   P G Q   +PT    + TT    +P  T  Q P          T    +
Sbjct: 3489 TTTTTVTPTPTPTGTQ---TPTTTPITTTTTVTPTPTPTGTQTPTTTPIT--TTTTVTPT 3543

Query: 134  RTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSS----TLCPICKTSDLTSTPSQPNFNT 189
             T    ++P+ +P   +T  +P       P P+     T  PI  T+ +T TP+     T
Sbjct: 3544 PTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 3597

Query: 190  CTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSP 249
             T             P P  TQ                   TT P + +     +P  + 
Sbjct: 3598 PTTTPITTTTTVTPTPTPTGTQTP-----------------TTTPITTTTTVTPTPTPTG 3640

Query: 250  AHSPAKQPLGKPDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQ 308
              +P   P+        +  P G Q  +    T   T  P       P   G  +P    
Sbjct: 3641 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTP------TPTPTGTQTPTTTP 3694

Query: 309  PTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
             T  +T  P       P  + T  P     T  T    T    G      T  +T  +V 
Sbjct: 3695 ITTTTTVTP------TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3748

Query: 369  PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTE 415
            P     G   P+  TP  +    +    P P G+               P P P G +T 
Sbjct: 3749 PTPTPTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 3805

Query: 416  PGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG 475
                +   +     P   GT +P                P T  +     P+        
Sbjct: 3806 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 3864

Query: 476  SKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPT 535
            + +P    T TT  +         PTP   +      +   T           TP P PT
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPT 3915

Query: 536  SQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQ 589
              Q P   P   + T +P           P+G      +P++T  +  P+       +P 
Sbjct: 3916 GTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 3967

Query: 590  AKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
              P+  +    P+ TP+  Q   T  + T     P P P  T TP T  + +        
Sbjct: 3968 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 4027

Query: 646  TPVVKAVP 653
            TP     P
Sbjct: 4028 TPTGTQTP 4035



 Score = 63.5 bits (153), Expect = 4e-09
 Identities = 85/416 (20%), Positives = 116/416 (27%), Gaps = 50/416 (12%)

Query: 272  PQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPP---QPTKPSTAEPRPPAGEAPAKS 328
            P P      T   T+ P P            +P PP     T P T  P PP        
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 329  ATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVF 388
             T  P+    T                +  +  +T  +  P   T   P  +  TP    
Sbjct: 1466 PTTTPSPPTTTPSPP-----------TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPA-- 1512

Query: 389  NDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAA 448
                      P  + P P         P     P +     P T  TT P          
Sbjct: 1513 -----STTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPT 1567

Query: 449  SKAAAKPKTMPKERAIC----PLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHL 504
            +     P T P          P         + +P+   T TT             TP +
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTP-I 1626

Query: 505  VEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQP 564
               T                    T LPP T+  PP   P   +   P     P     P
Sbjct: 1627 TPPTS------------------TTTLPPTTTPSPP---PTTTTTPPPTTTPSPPTTTTP 1665

Query: 565  SGPLPAKASP--LSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKP 622
            S P+    +P   +T +SP+ +  SP    +    P+ TPSS     T   +   P P P
Sbjct: 1666 SPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725

Query: 623  PPETTPTP-ATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSP 677
               TTP+P  TP   +      P T     +   P           P+S     +P
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 63.5 bits (153), Expect = 4e-09
 Identities = 77/355 (21%), Positives = 118/355 (33%), Gaps = 20/355 (5%)

Query: 1358 SSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAH 1417
            ++P+ P++ +     P +  P  P TT   P P   P   ++  +      +PSP +T  
Sbjct: 1420 TTPSPPTTTTTT--PPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPTTTPSPPTTTP 1477

Query: 1418 SYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSS 1477
            S    PTT      T      P+   +        P +++     T  PS   +   +  
Sbjct: 1478 S---PPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP 1534

Query: 1478 PPLSPSSPSESPTFSPGK---MGPRATAEFSTQTPSPAPASDMPRSPGAPTPSP-----M 1529
            P  +PS P+ +P   P     + P  T      T +  P +  P  P   TPSP      
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT 1594

Query: 1530 VAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQP 1589
                T TP  P+T       ++  +P     +    S+ T     + S  P  + T    
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654

Query: 1590 TTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVP 1649
            TT     TT PS        P P   P  P      P         P    S    ++  
Sbjct: 1655 TTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPITTTTT 1714

Query: 1650 GTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP 1704
             +S   P P  P T +        P+P   T     +T+L        L   P+P
Sbjct: 1715 PSSTTTPSP--PPTTMTTPSPTTTPSPPTTT-----MTTLPPTTTSSPLTTTPLP 1762



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/458 (20%), Positives = 156/458 (34%), Gaps = 67/458 (14%)

Query: 1299 DPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHS 1358
            +P      P+T  T+ T    P    TPT++  +    +            T  P+   +
Sbjct: 1892 NPTPPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-T 1950

Query: 1359 SPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAH 1417
            +  +P+        P +    TP TT     P   P G  TP + P  +  + +P+ T  
Sbjct: 1951 TTVTPTPTPTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT 2006

Query: 1418 SYGHSPTTANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASS 1476
                +PTT    + T   P   P+G     +     P++ +     TP P+   +   + 
Sbjct: 2007 GT-QTPTTTPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2061

Query: 1477 SPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQT 1536
                +  +P+ +PT   G   P  T   +T T +P P    P     PT +P+    T T
Sbjct: 2062 ITTTTTVTPTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVT 2115

Query: 1537 PHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THG 1593
            P    TP     ++    P    T  +   + T     + +T+P+ + T   PT   T  
Sbjct: 2116 P----TPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGT 2169

Query: 1594 YSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSR 1653
             + TT P  +     P   P   + P+                         + +  T+ 
Sbjct: 2170 QTPTTTPITTTTTVTPTPTPTGTQTPTT------------------------TPITTTTT 2205

Query: 1654 VEPGP-----RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---G 1705
            V P P     +TP T  +   T V PTP     Q    T +          + P P   G
Sbjct: 2206 VTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTG 2260

Query: 1706 RQSTAVQPLVINLN---AQEHTFLATATTVSITMASSV 1740
             Q+    P+            T   T TT  IT  ++V
Sbjct: 2261 TQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2298



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 1946 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2004

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2005 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2059

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2060 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2115

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2116 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2165

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2166 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2224 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2282

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2283 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2337

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2338 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2367



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2015 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2073

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2074 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2128

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2129 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2184

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2185 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2234

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2235 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2293 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2351

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2352 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2406

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2407 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2436



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2084 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2142

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2143 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2197

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2198 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2253

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2254 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2303

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2304 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2362 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2420

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2421 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2475

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2476 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2505



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2153 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2211

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2212 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2266

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2267 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2322

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2323 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2372

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2373 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2431 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2489

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2490 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2544

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2545 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2574



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2222 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2280

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2281 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2335

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2336 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2391

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2392 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2441

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2442 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2500 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2558

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2559 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2613

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2614 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2643



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2291 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2349

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2350 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2404

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2405 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2460

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2461 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2510

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2511 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2569 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2627

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2628 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2682

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2683 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2712



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2360 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2418

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2419 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2473

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2474 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2529

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2530 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2579

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2580 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2638 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2696

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2697 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2751

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2752 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2781



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2429 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2487

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2488 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2542

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2543 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2598

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2599 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2648

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2649 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2707 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2765

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2766 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2820

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2821 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2850



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2498 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2556

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2557 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2611

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2612 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2667

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2668 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2717

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2718 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2776 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2834

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2835 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2889

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2890 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2919



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2567 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2625

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2626 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2680

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2681 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2736

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2737 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2786

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2787 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2845 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2903

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2904 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 2958

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 2959 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2988



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2636 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2694

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2695 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2749

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2750 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2805

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2806 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2855

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2856 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2914 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 2972

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 2973 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3027

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3028 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3057



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2705 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2763

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2764 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2818

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2819 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2874

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2875 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2924

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2925 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 2983 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3041

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3042 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3096

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3097 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3126



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2774 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2832

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2833 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2887

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2888 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 2943

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 2944 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 2993

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 2994 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3052 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3110

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3111 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3165

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3166 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3195



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2843 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2901

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2902 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 2956

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 2957 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3012

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3013 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3062

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3063 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3121 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3179

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3180 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3234

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3235 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3264



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2912 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 2970

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 2971 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3025

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3026 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3081

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3082 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3131

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3132 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3190 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3248

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3249 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3303

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3304 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3333



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 2981 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3039

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3040 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3094

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3095 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3150

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3151 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3200

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3201 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3259 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3317

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3318 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3372

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3373 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3402



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3050 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3108

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3109 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3163

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3164 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3219

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3220 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3269

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3270 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3328 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3386

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3387 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3441

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3442 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3471



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3119 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3177

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3178 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3232

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3233 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3288

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3289 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3338

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3339 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3397 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3455

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3456 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3510

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3511 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3540



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3188 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3246

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3247 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3301

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3302 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3357

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3358 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3407

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3408 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3466 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3524

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3525 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3579

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3580 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3609



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3257 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3315

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3316 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3370

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3371 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3426

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3427 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3476

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3477 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3535 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3593

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3594 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3648

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3649 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3678



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3326 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3384

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3385 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3439

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3440 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3495

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3496 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3545

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3546 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3604 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3662

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3663 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3717

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3718 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3747



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3395 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3453

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3454 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3508

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3509 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3564

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3565 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3614

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3615 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3673 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3731

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3732 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3786

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3787 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3816



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3464 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3522

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3523 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3577

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3578 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3633

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3634 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3683

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3684 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3742 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3800

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3801 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3855

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3856 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3885



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3533 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3591

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3592 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3646

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3647 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3702

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3703 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3752

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3753 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3811 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3869

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3870 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3924

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3925 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 3954



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3602 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3660

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3661 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3715

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3716 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3771

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3772 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3821

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3822 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3880 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 3938

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 3939 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 3993

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 3994 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4023



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 96/450 (21%), Positives = 155/450 (34%), Gaps = 44/450 (9%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+ T    P    TPT++  +    +            T  P+   ++  +P+  
Sbjct: 3671 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITT-TTTVTPTPT 3729

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS-PAGSERSPSPSSTAHSYGHSPTT 1425
                  P +    TP TT     P   P G  TP + P  +  + +P+ T      +PTT
Sbjct: 3730 PTGTQTPTT----TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGT-QTPTT 3784

Query: 1426 ANYGSQTEDLPQ-APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
                + T   P   P+G     +     P++ +     TP P+   +   +     +  +
Sbjct: 3785 TPITTTTTVTPTPTPTGT----QTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 3840

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPR 1544
            P+ +PT   G   P  T   +T T +P P    P     PT +P+    T TP    TP 
Sbjct: 3841 PTPTPT---GTQTPTTTPITTTTTVTPTPT---PTGTQTPTTTPITTTTTVTP----TPT 3890

Query: 1545 LVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPT---THGYSQTTPPS 1601
                ++    P    T  +   + T     + +T+P+ + T   PT   T   + TT P 
Sbjct: 3891 PTGTQTPTTTPITTTTTVTPTPTPTGT--QTPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948

Query: 1602 VSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGP--- 1658
             +     P   P   + P+               P         + +  T+ V P P   
Sbjct: 3949 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPT-GTQTPTTTPITTTTTVTPTPTPT 4007

Query: 1659 --RTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYGLALDPIP---GRQSTAVQP 1713
              +TP T  +   T V PTP     Q    T +          + P P   G Q+    P
Sbjct: 4008 GTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT-----TVTPTPTPTGTQTPTTTP 4062

Query: 1714 LVINLN---AQEHTFLATATTVSITMASSV 1740
            +            T   T TT  IT  ++V
Sbjct: 4063 ITTTTTVTPTPTPTGTQTPTTTPITTTTTV 4092



 Score = 61.2 bits (147), Expect = 2e-08
 Identities = 72/313 (23%), Positives = 115/313 (36%), Gaps = 53/313 (16%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+TP  S T L    + S PT++ ++                 T  P    ++P +P ++
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTT--------------PPPTTTPSPPTTTPITPPTS 1552

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRG--YMTPASPAGSERSPSPSSTAHSYGHSPT 1424
            +  +  P +  P  P TT   P P   P      TP+ P  +  +P P++T       PT
Sbjct: 1553 TTTL--PPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP----SPPT 1606

Query: 1425 TANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS 1484
            T          P  P+            P++        P  +        S PP + ++
Sbjct: 1607 TTTTTPPPTTTPSPPT----------TTPITPPTSTTTLPPTT------TPSPPPTTTTT 1650

Query: 1485 PSESPTFSPGKMGPRATAEFSTQTPSP--APASDMPRSPGAPTPSPMVAQGTQTPHRPST 1542
            P  + T SP      +    +T TP P   P+S +  +P  PT +      T TP  P T
Sbjct: 1651 PPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTPSSPIT 1710

Query: 1543 PRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSV 1602
                   ++  +P             T M   S +T+P   PT T  T    + ++P + 
Sbjct: 1711 TTTTPSSTTTPSP-----------PPTTMTTPSPTTTP-SPPTTTMTTLPPTTTSSPLTT 1758

Query: 1603 SQLPPEPPGPPGF 1615
            + LPP    PP F
Sbjct: 1759 TPLPPSIT-PPTF 1770



 Score = 56.6 bits (135), Expect = 5e-07
 Identities = 150/728 (20%), Positives = 205/728 (28%), Gaps = 139/728 (19%)

Query: 15   PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
            P P     P P   P P     PS P      P      S   P      P P   P P 
Sbjct: 1564 PPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSP--PTTTTTTPPPTTTPSPP 1621

Query: 75   STSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSR 134
            +T+    P          +P+P   + TTP    P  T    P       P  T      
Sbjct: 1622 TTTPITPPTSTTTLPPTTTPSPPPTTTTTP----PPTTTPSPPTTTTPSPPITTTTTPPP 1677

Query: 135  TQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCH 194
            T       + +P   S PT+  + P     PSS +      S  T+TPS P     T   
Sbjct: 1678 TTTPSSPITTTP---SPPTTTMTTPSPTTTPSSPITTTTTPSS-TTTPSPPPTTMTT--- 1730

Query: 195  NKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPA 254
                      P+P  T       +           +TT P   S   +  P  SP  +  
Sbjct: 1731 ----------PSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS---ITPPTFSPFSTTT 1777

Query: 255  KQ----PL---------GKPDQERSRGPGGPQ--------PGSRQAETARATSVP----- 288
                  PL         GKP+  +   PGG          PG     + RAT  P     
Sbjct: 1778 PTTPCVPLCNWTGWLDSGKPNFHK---PGGDTELIGDVCGPGWAANISCRATMYPDVPIG 1834

Query: 289  ------------GPAQAAAPPEVGRVSP------------------QPPQPTKPSTAEPR 318
                        G        + G V P                  QP   T  +T  P 
Sbjct: 1835 QLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTTTTTENPT 1894

Query: 319  PP----------AGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQ 368
            PP              P  + T  P     T  T    T    G      T  +T  +V 
Sbjct: 1895 PPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVT 1954

Query: 369  PEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP------------GPGPAP-GAKTE 415
            P     G   P+  TP  +    +    P P G+               P P P G +T 
Sbjct: 1955 PTPTPTGTQTPTT-TP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTP 2011

Query: 416  PGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVG 475
                +   +     P   GT +P                P T  +     P+        
Sbjct: 2012 TTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTP-TGTQTPTTTPITTTTTVTP 2070

Query: 476  SKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPT 535
            + +P    T TT  +         PTP   +      +   T           TP P PT
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT---------TVTPTPTPT 2121

Query: 536  SQQPPVGAPHRASGT-SPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKA-----SPQ 589
              Q P   P   + T +P           P+G      +P++T  +  P+       +P 
Sbjct: 2122 GTQTPTTTPITTTTTVTPTP--------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT 2173

Query: 590  AKPLRAS---EPSKTPSSVQEKKTR-VPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPA 645
              P+  +    P+ TP+  Q   T  + T     P P P  T TP T  + +        
Sbjct: 2174 TTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP 2233

Query: 646  TPVVKAVP 653
            TP     P
Sbjct: 2234 TPTGTQTP 2241



 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 92/462 (19%), Positives = 128/462 (27%), Gaps = 94/462 (20%)

Query: 312  PSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEA 371
            P T  P PP         T  P+    T  T    T           +   T  +  P  
Sbjct: 1401 PPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTP---------SPPITTTTTPPPT 1451

Query: 372  DTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPK 431
             T   P  +  TP      +     P P  + P P         P     P +     P 
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1511

Query: 432  TGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQ 491
               TT P          +     P T P      P+                T TT    
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP-------------TSTTT--- 1555

Query: 492  VCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQ--PPVGAPHRASG 549
                    PT                           TP PPPT+    PP   P   + 
Sbjct: 1556 ------LPPTT--------------------------TPSPPPTTTTTPPPTTTPSPPTT 1583

Query: 550  TSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKK 609
            T+P     P  +   + P     SP +T  +  P   +P       S P+ TP +     
Sbjct: 1584 TTP----SPPTITTTTPPPTTTPSPPTTTTTTPPPTTTP-------SPPTTTPITPPTST 1632

Query: 610  TRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPY 669
            T +P    P   PPP TT TP      S      P+ P+       P    +  +   P 
Sbjct: 1633 TTLPPTTTP--SPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690

Query: 670  SQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSEIHKVGS 729
                + +  S + T  S    +++ S  T            +  T P PP+ +       
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT------- 1743

Query: 730  SMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAF 771
                      L P+  S PL++         P   SITP  F
Sbjct: 1744 -------MTTLPPTTTSSPLTT--------TPLPPSITPPTF 1770



 Score = 55.5 bits (132), Expect = 1e-06
 Identities = 68/289 (23%), Positives = 98/289 (33%), Gaps = 19/289 (6%)

Query: 1398 MTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSAS 1457
            +T  SP  +  SP P+ST       PTT      T      P+            P++ +
Sbjct: 1396 ITTPSPPTTTPSPPPTSTTTL---PPTTTPSPPTTTTTTPPPT-------TTPSPPITTT 1445

Query: 1458 DGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDM 1517
                 T  PS   S   +  P  +PS P+ +P+       P  T   +T TP P      
Sbjct: 1446 TTPPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTT---TTTTPPPTTTPSP 1502

Query: 1518 PRS-PGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASA 1576
            P + P  P  S      T TP  P+T       ++  +P     +    S+ T     + 
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562

Query: 1577 STSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALP 1636
            S  P  + T    TT     TT PS   +    P P   P  P+     P          
Sbjct: 1563 SPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPT 1622

Query: 1637 AENIS-LCRISSVPGTSRVEPGPRT----PGTAVVDLRTAVKPTPIILT 1680
               I+     +++P T+   P P T    P T      T   P+P I T
Sbjct: 1623 TTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITT 1671



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 60/257 (23%), Positives = 89/257 (34%), Gaps = 31/257 (12%)

Query: 1298 MDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLH 1357
            + P      P T  T+P     P   +T T S  +     P    T      T       
Sbjct: 1556 LPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPT 1615

Query: 1358 SSPASPSSA-----SKEIGMPFSQGPGTPATTAVAPCPAGLPRG--YMTPASPAGSERSP 1410
            ++P+ P++      +    +P +  P  P TT   P P   P      TP+ P  +  +P
Sbjct: 1616 TTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTP 1675

Query: 1411 SPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAY 1470
             P++T  S    P T      T   P   +    +       P++ +     T  PS   
Sbjct: 1676 PPTTTPSS----PIT------TTPSPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725

Query: 1471 SYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMV 1530
            +   + SP  +PS P+ + T  P            T T SP   + +P S   PT SP  
Sbjct: 1726 TTMTTPSPTTTPSPPTTTMTTLP-----------PTTTSSPLTTTPLPPSITPPTFSPF- 1773

Query: 1531 AQGTQTPHRPSTPRLVW 1547
               T TP  P  P   W
Sbjct: 1774 --STTTPTTPCVPLCNW 1788



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 55/250 (22%), Positives = 79/250 (31%), Gaps = 18/250 (7%)

Query: 3025 CTTPAGQFVDFPAT-AAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTY 3083
            C  P  + +  P+     P+ P   T    P   P  P  +  +  PT    P     T 
Sbjct: 1388 CCWPMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTT 1447

Query: 3084 PGPSTYPAPAFPPGASYP--AEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPA----- 3136
            P P+T P+P      + P    P  P      PT      TP P T +T  P P      
Sbjct: 1448 PPPTTTPSPPISTTTTPPPTTTPSPPTTTPSPPT-----TTPSPPTTTTTTPPPTTTPSP 1502

Query: 3137 DSRAPLQKPRQ-TSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVP 3195
             +  P+  P   T+L       P        P     S P+ T  + P  ++       P
Sbjct: 1503 PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTP 1562

Query: 3196 EVP---RAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQ 3252
              P         + + SP PT  + S  T      P         +  T    +T P   
Sbjct: 1563 SPPPTTTTTPPPTTTPSP-PTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPP 1621

Query: 3253 RLEPLGPGSS 3262
               P+ P +S
Sbjct: 1622 TTTPITPPTS 1631



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 44/215 (20%), Positives = 70/215 (32%), Gaps = 15/215 (6%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYP- 3084
            TTP       P T   P+ P+  T    P   P  P  +  +  PT    P    P  P 
Sbjct: 1570 TTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPP 1629

Query: 3085 ------GPSTYPAP-----AFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFP 3133
                   P+T P+P       PP  + P+ P          T      T  P++  T  P
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689

Query: 3134 VPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGK 3193
             P  +      P  T  + +      +     SP     + PS T+   P  ++      
Sbjct: 1690 SPPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTT---MTT 1746

Query: 3194 VPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVP 3228
            +P    +    +    P+ T P+ S +++     P
Sbjct: 1747 LPPTTTSSPLTTTPLPPSITPPTFSPFSTTTPTTP 1781



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 97/479 (20%), Positives = 152/479 (31%), Gaps = 100/479 (20%)

Query: 1307 PLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSA 1366
            P+T  T+P     P S  T T S  +     P    T         P+   ++P+S ++ 
Sbjct: 1668 PITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTTP------SSPITTTTTPSSTTT- 1720

Query: 1367 SKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPAS--PAGSERSPSPSSTAHSYGHSPT 1424
                       P  P TT   P P   P    T  +  P  +  SP  ++        PT
Sbjct: 1721 -----------PSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITPPT 1769

Query: 1425 TANYGSQTEDLPQAP----SGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPL 1480
             + + + T   P  P    +G   +G+    KP   ++  G    P  A +   S    +
Sbjct: 1770 FSPFSTTTPTTPCVPLCNWTGWLDSGKPNFHKPGGDTELIGDVCGPGWAANI--SCRATM 1827

Query: 1481 SPSSP-----------------SESPTFSPGKMGPRATA---EFSTQ-----TPSPAPAS 1515
             P  P                  ++    PG + P A     E + Q     T      +
Sbjct: 1828 YPDVPIGQLGQTVVCDVSVGLICKNEDQKPGGVIPMAFCLNYEINVQCCECVTQPTTMTT 1887

Query: 1516 DMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHAS 1575
                +P  PT +P+    T TP    TP     ++    P    T  +   + T     +
Sbjct: 1888 TTTENPTPPTTTPITTTTTVTP----TPTPTGTQTPTTTPITTTTTVTPTPTPTGT--QT 1941

Query: 1576 ASTSPLCSPTETQPT---THGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGW 1632
             +T+P+ + T   PT   T   + TT P  +     P   P   + P+            
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTT----------- 1990

Query: 1633 GALPAENISLCRISSVPGTSRVEPGP-----RTPGTAVVDLRTAVKPTPIILTDQGMDLT 1687
                         + +  T+ V P P     +TP T  +   T V PTP     Q    T
Sbjct: 1991 -------------TPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTT 2037

Query: 1688 SLAVEARKYGLALDPIP---GRQSTAVQPLVINLN---AQEHTFLATATTVSITMASSV 1740
             +          + P P   G Q+    P+            T   T TT  IT  ++V
Sbjct: 2038 PITTTT-----TVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTV 2091



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 57/274 (20%), Positives = 79/274 (28%), Gaps = 53/274 (19%)

Query: 3026 TTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG 3085
            TTP+              TP   T    P   P  P  S  +  PT    P     T P 
Sbjct: 1475 TTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSPPTTTTTTPP 1534

Query: 3086 PSTYPAP----------------------------AFPPGASYPAEP--GLPNQQAFRPT 3115
            P+T P+P                              PP  + P+ P    P+      T
Sbjct: 1535 PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPTITTT 1594

Query: 3116 GHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAP 3175
                  TP P T +T  P P  + +P   P  T +       P        P    S  P
Sbjct: 1595 TPPPTTTPSPPTTTTTTPPPTTTPSP---PTTTPI------TPPTSTTTLPPTTTPSPPP 1645

Query: 3176 SETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVPRNYVMID 3235
            + T+   P  +        P  P      + + +P PT    S  T+             
Sbjct: 1646 TTTTTPPPTTTPSPPTTTTPSPPI-----TTTTTPPPTTTPSSPITTTPS---------P 1691

Query: 3236 DISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEP 3269
              + +T  S +T P S       P S+  P   P
Sbjct: 1692 PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPP 1725



 Score = 37.7 bits (86), Expect = 0.23
 Identities = 46/192 (23%), Positives = 60/192 (31%), Gaps = 12/192 (6%)

Query: 3036 PATAAAPATPSG-PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAF 3094
            P T     TP+  PT  Q P   P     +  +  PT  G            +T      
Sbjct: 4085 PITTTTTVTPTPTPTGTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPT 4143

Query: 3095 PPGASYPAEPGLPNQQAFRPTGHYAG-QTPMPT---TQSTLFPVPADSRAPLQKPRQTSL 3150
            P G   P    +       PT    G QTP  T   T +T+ P P  +      P  TS 
Sbjct: 4144 PTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST 4203

Query: 3151 ADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSP 3210
            A + +   +N      P    S+  +  S S P   S      +P           S   
Sbjct: 4204 APIAELTTSN------PPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPT 4257

Query: 3211 APTYPSDSHYTS 3222
            APT  S  H  S
Sbjct: 4258 APTTTSGGHTLS 4269



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 47/233 (20%), Positives = 69/233 (29%), Gaps = 38/233 (16%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
            P   P+S   +P    P  P++   + P   + +    + +        S P +  +   
Sbjct: 1406 PSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPP 1465

Query: 3741 PQAQPQLQGRQAAPGPQQSQSP--SSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQAR 3798
            P   P       +P P  + SP  ++   P    +  P T        + PP    T   
Sbjct: 1466 PTTTPSPPTTTPSP-PTTTPSPPTTTTTTPPPTTTPSPPTTTP-----ITPPASTTTLPP 1519

Query: 3799 LQQQSQPTTRGSAPAASQ--------------------PAGKPQPGPSTATGPQPA---G 3835
                S PTT  + P  +                     P   P P P+T T P P     
Sbjct: 1520 TTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPS 1579

Query: 3836 PPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
            PP     +    T   P     P   P+P   P        P  TP  P   P
Sbjct: 1580 PPTTTTPSPPTITTTTP----PPTTTPSP---PTTTTTTPPPTTTPSPPTTTP 1625



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 44/212 (20%), Positives = 62/212 (29%), Gaps = 18/212 (8%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAE 3740
            P + P+S   +P    P  P++   + P   + +    +     +      P    S   
Sbjct: 1507 PITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSP-- 1564

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
            P            P P  + +PS    P+   +  P T          P     T     
Sbjct: 1565 PPTTTTTPPPTTTPSPPTTTTPSP---PTITTTTPPPTTTPSP-----PTTTTTTPPPTT 1616

Query: 3801 QQSQPTTRGSAPAASQ----PAGKPQPGPSTATGPQPA---GPPRAEQTNGSKGTAKAPQ 3853
              S PTT    P  S     P   P P P+T T P P     PP     +    T   P 
Sbjct: 1617 TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP 1676

Query: 3854 QGRAPQAQPAPGPG-PAGVKAGARPGGTPGAP 3884
                P +     P  P        P  TP +P
Sbjct: 1677 PTTTPSSPITTTPSPPTTTMTTPSPTTTPSSP 1708



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 19/67 (28%), Positives = 25/67 (37%), Gaps = 6/67 (8%)

Query: 596  SEPSKTPSSVQEKKTRVPTKAEPMPK------PPPETTPTPATPKVKSGVRRAEPATPVV 649
            S P+ TPS      T +P    P P       PPP TTP+P      +      P+ P+ 
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 650  KAVPEAP 656
                  P
Sbjct: 1460 TTTTPPP 1466



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 27/93 (29%), Positives = 29/93 (31%), Gaps = 15/93 (16%)

Query: 3803 SQPTTRGSAPAAS----QPAGKPQPGPSTATGPQPA---GPPRAEQTNGSKGTAKAPQQG 3855
            S PTT  S P  S     P   P P  +T T P P     PP    T     T  +P   
Sbjct: 1400 SPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPIS 1459

Query: 3856 RAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
                  P   P P        P  TP  P   P
Sbjct: 1460 TTTTPPPTTTPSP--------PTTTPSPPTTTP 1484


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 76.6 bits (187), Expect = 4e-13
 Identities = 147/654 (22%), Positives = 226/654 (34%), Gaps = 82/654 (12%)

Query: 1009 SPSRRQRLEEAKQQRKARH-RSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRI 1067
            SPS R+R    +++RK  H RS      +   S   E+  +  EL     K++E   Q  
Sbjct: 179  SPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEA 238

Query: 1068 RSTAR-----------KTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQA-AEM 1115
             ST+            + +    E  +++ +E+ KT P + S  +  S T     +    
Sbjct: 239  TSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRP 298

Query: 1116 EELHRSSCSEYSPS--PSLDSEAEALDGGPSRLYKSGSEY--NLPTFMSLYSPTETPSGS 1171
               HRS    YSP   PS           P R       +  +          + + SGS
Sbjct: 299  RRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGS 358

Query: 1172 STTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQD 1231
            S++ SS R     ++  +         +R    A+  R  H  PS P  P          
Sbjct: 359  SSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHR-PSPPATPPPKTR---HS 414

Query: 1232 TTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFL 1291
             T ++  +  +     +P            +TS  + + +    R+      K ++ +  
Sbjct: 415  PTPQQSNRTRKSRVSVSPG-----------RTSGKVTKHKGTEKRESPSPAPKPRKVELS 463

Query: 1292 NAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQ 1351
             +E       +  GG +    S  Q       +  +SSDS       D R  +   K  +
Sbjct: 464  ESE-------EDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGE 516

Query: 1352 DPLKLHSSPA-----SPSSASKEIGMPFSQ--GPGTPATTAV-APCPAGLPRGYMTPASP 1403
               +   SP+     SP    KE      +   P  P T    +P PA  PR   TP  P
Sbjct: 517  VGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPP 576

Query: 1404 AGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGT 1463
                R+PSP     S   SP   +   Q    P  P       R     P         +
Sbjct: 577  P-RRRTPSPPPRRRS--PSPRRYSPPIQRRYSPSPPPK-----RRTASPPPPPKRRASPS 628

Query: 1464 PQPSRAYSYFAS----SSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTP----SPAPAS 1515
            P P R  S+       SSP     SPS S     G    R+T E  +  P    SP+P  
Sbjct: 629  PPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPR- 687

Query: 1516 DMPRSPGAPTPSPMVAQG-TQTPHRPSTP----RLVWQESSQEAPFMVITLASDASSQTR 1570
              PR+P   +  P V +G + +P R  +P    R + + S    P  +   AS +    R
Sbjct: 688  --PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR 745

Query: 1571 MVHASASTS----PLC-------SPTETQPTTHGYSQTTPPSVSQLPPEPPGPP 1613
             V +S S S    P         SP ++Q  +  +S   P   ++ P   P PP
Sbjct: 746  RVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPP 799



 Score = 65.9 bits (159), Expect = 8e-10
 Identities = 143/670 (21%), Positives = 227/670 (33%), Gaps = 111/670 (16%)

Query: 527  EPTP-LPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK 585
            E TP LP P+ +          S +  LK   P+ + +P  P P K S    +      +
Sbjct: 218  EKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPR 277

Query: 586  ASPQAKPLRASEPSKTPSSVQEKKTRVPTKAE--PMPKPPPETTPTPATPKVKSGVRRAE 643
            +  ++K  R+   S++PS  + ++          P  +P P   P+P         RR  
Sbjct: 278  SRSRSKS-RSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPR--------RRTP 328

Query: 644  PATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQ 703
            P     + +P  P+   +   V +     AS S  S S +   S        + T    +
Sbjct: 329  P-----RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPR 383

Query: 704  EVEQLDSAGVTGP---HPPSPSEIHKVGSSMRPLLQAQG--------LAPSERSKPLSSG 752
            +  +L S   + P   H PSP       +   P  Q           ++P   S  ++  
Sbjct: 384  KTRRL-SPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKH 442

Query: 753  TGEEQKQRPHSLSITPEAFDSDEELEDILEE--DEDSAEWRRRREQQDTAESSDDFGSQL 810
             G E+++ P S +  P   +  E  ED   +    DS + RR+  +Q+   SSD   S  
Sbjct: 443  KGTEKRESP-SPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSS 501

Query: 811  RHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLA 870
              D               + P R+     E   RR+     +   +  +    TS RG  
Sbjct: 502  SED---------------ERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRR 546

Query: 871  KHGT------QKGGPRPRPEPSQE--PAALPKRRLPHNATTGYEELLPEGGSAEATDGSG 922
            +         ++  P P P P +   P   P+RR P           P   S      S 
Sbjct: 547  RRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPP--------PRRRSPSPRRYSP 598

Query: 923  TLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDRE----PELEMESLTGSPEDRSRGE 978
             +Q   RR+                    P P   R     P       + SP  + R  
Sbjct: 599  PIQ---RRY-------------------SPSPPPKRRTASPPPPPKRRASPSPPPKRRVS 636

Query: 979  HSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIE 1038
            HS      +   T   SP SLSS +    SSPSR  R   + Q  K    S  P  P   
Sbjct: 637  HSPPPKQRSSPVTKRRSP-SLSS-KHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTS 694

Query: 1039 DSSEEEELREEEELLREQEK----------MREVEQQRIRSTARKTRRDKEELRAQRR-- 1086
             S             R Q             R  E ++I+  A  + +    + + R   
Sbjct: 695  SSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS 754

Query: 1087 ---RERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGP 1143
                  +K PP+  SP++  SP+     A  ++   ++     SPSP  +S+ E   GG 
Sbjct: 755  GSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVK---KAKSPTPSPSPPRNSDQEG--GGK 809

Query: 1144 SRLYKSGSEY 1153
             +  K   ++
Sbjct: 810  KKKKKKDKKH 819



 Score = 63.9 bits (154), Expect = 3e-09
 Identities = 144/680 (21%), Positives = 228/680 (33%), Gaps = 112/680 (16%)

Query: 871  KHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGLRR 930
            +H T+   P P PE  ++   LP+  +           + E    EAT  S  L+     
Sbjct: 202  RHRTKSRSPSPAPEKKEKTPELPEPSVK----------VKEPSVQEATSTSDILK----- 246

Query: 931  FKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSY 990
                             + +  +PS ++  + E E     P  RSR +  S   + +PS+
Sbjct: 247  -----------VPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPSH 295

Query: 991  T-----SGTSPTSLSSLEEDSD-SSPSRRQRLEEAKQQRKARH-RSHGPLLPTIEDSSEE 1043
            T       +   S S     S    PS R+R    +     RH RS  P+      S+  
Sbjct: 296  TRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASL 355

Query: 1044 EELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDA 1103
                      R +   ++   +R  S  RKTRR        RRR R  +PP+   P    
Sbjct: 356  SGSSSSSSSSRSRSPPKK-PPKRTSSPPRKTRRLSPSASPPRRRHR-PSPPATPPPKTRH 413

Query: 1104 SPTEELRQAAEMEEL-------------HRSSCSEYSPSPSLD------SEAEALDGGPS 1144
            SPT +         +             H+ +    SPSP+        SE+E   GG  
Sbjct: 414  SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGG-- 471

Query: 1145 RLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQ 1204
            ++  + S      +      + + SGSS++    RP +S        ++  E+ +R++  
Sbjct: 472  KMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRS-------HVKNGEVGRRRRHS 524

Query: 1205 AAGARGPHGGPSQ-PTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQT 1263
             + +  P     Q  T PRG           R   +   P+    P            +T
Sbjct: 525  PSRSASPSPRKRQKETSPRGRRRRSPSPPPTR---RRRSPSPAPPPRRRRTPTPPPRRRT 581

Query: 1264 SQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSF 1323
                 R R  S R                    Y  P+++   P  P    T    P   
Sbjct: 582  PSPPPRRRSPSPR-------------------RYSPPIQRRYSPSPPPKRRTASPPPPPK 622

Query: 1324 STPTSSDSSGGRVI----PDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPG 1379
               + S     RV     P  R +    + +      H   +SPS +++E   P      
Sbjct: 623  RRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRH 682

Query: 1380 TPATTAVAPCPAGLPRGYMTPASPAGSER-SPSPSS-TAHSYGHSPTTANYGSQTEDLPQ 1437
            +P+    AP  +  P      AS +   R SPSPS+        +P            PQ
Sbjct: 683  SPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQ 742

Query: 1438 APSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSS-PSESPTFSPGKM 1496
            +             + +S+S    G+P+P       A+  PP  PS   S+SP+ +    
Sbjct: 743  S------------VRRVSSSRSVSGSPEP-------AAKKPPAPPSPVQSQSPSTNWSPA 783

Query: 1497 GPRATAEFSTQTPSPAPASD 1516
             P   A+  T +PSP   SD
Sbjct: 784  VPVKKAKSPTPSPSPPRNSD 803



 Score = 63.9 bits (154), Expect = 3e-09
 Identities = 131/635 (20%), Positives = 215/635 (33%), Gaps = 87/635 (13%)

Query: 52  ARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPT--PKQASATTPG-HES 108
           +RS +  P   P P   P P   +  RR+ P  P  ++R+ SP    +++SA+  G   S
Sbjct: 304 SRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP--PPRHRRSRSPVRRRRRSSASLSGSSSS 361

Query: 109 PRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSP----DRGSTPTSPYSVPQIAPL 164
              +R++ P  +    P+RT     +T+R   SPS SP     R S P +P    + +P 
Sbjct: 362 SSSSRSRSPPKKP---PKRTSSPPRKTRR--LSPSASPPRRRHRPSPPATPPPKTRHSPT 416

Query: 165 PSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQR 224
           P  +     + S ++ +P + +         +        P P   ++ E          
Sbjct: 417 PQQS--NRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMA 474

Query: 225 ALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPL------GKPDQERSRGP---GGPQPG 275
           A           +  QQ  S + S + S  ++P       G+  + R   P     P P 
Sbjct: 475 AADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPR 534

Query: 276 SRQAETA---RATSVPGPAQAAAPPEVGRVSPQ---PPQPTKPSTAEPRPPAGEAPAKSA 329
            RQ ET+   R    P P     PP   R SP    PP+  +  T  PR      P +  
Sbjct: 535 KRQKETSPRGRRRRSPSP-----PPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRR 589

Query: 330 TAVPAGLGATEQTQEGLT--GKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIV 387
           +  P       Q +   +   K          +     S  P+      P P + +  + 
Sbjct: 590 SPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVT 649

Query: 388 FNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQA 447
              +   +     GS P          +P  R  P   P A P+T  +  P    A    
Sbjct: 650 KRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRA-PQTSSSPPPVRRGASSSP 708

Query: 448 ASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEK 507
             + +  P T P  R             S++P                   +P+P  V +
Sbjct: 709 QRRQSPSPSTRPIRRV------------SRTPEPKKIKKAA----------SPSPQSVRR 746

Query: 508 TEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGP 567
                    + R + GS       P P +++PP  AP      SP++ + P     P+ P
Sbjct: 747 V-------SSSRSVSGS-------PEPAAKKPP--AP-----PSPVQSQSPSTNWSPAVP 785

Query: 568 LPAKASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT 627
           +    SP  + + P  S      K  +  +  K     + KK +   K + +        
Sbjct: 786 VKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKKEKAVAAAAAAAV 845

Query: 628 PTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAE 662
              A     + + + EP      A PE  K  E+E
Sbjct: 846 TPAAIAAATTTLAQEEPV-----AAPEPKKETESE 875



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 131/689 (19%), Positives = 244/689 (35%), Gaps = 128/689 (18%)

Query: 78  RRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQR 137
           R  + KE    +R  S +P++  + +P   SPR  R   P  +E    +R+     R + 
Sbjct: 154 RDKEEKESSREKRERSRSPRRRKSRSP---SPR--RRSSPVRRER---KRSHSRSPRHRT 205

Query: 138 SGRSPSVSPDRGS-TPTSP--------------------YSVPQIAPLPSSTLCPICKTS 176
             RSPS +P++   TP  P                      VP+  P+P        K S
Sbjct: 206 KSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNS 265

Query: 177 --DLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAP 234
             +     ++P   + ++  ++  ++   +  P                R+       +P
Sbjct: 266 KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSR--------SRSYSPRRRPSP 317

Query: 235 RSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPG--PAQ 292
           R +   +  +P       P  +    P + R R        S  + ++R+ S P   P +
Sbjct: 318 RRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377

Query: 293 AAAPP-EVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLF 351
            ++PP +  R+SP    P +     P PPA   P    +  P     T +++  ++    
Sbjct: 378 TSSPPRKTRRLSPSASPPRRRH--RPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPG-- 433

Query: 352 GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPG 411
                   + S  ++     + +  P+P+    K+  +++ ++ G K   +         
Sbjct: 434 --------RTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQY 485

Query: 412 AKTEPGARMGPGSGPGA---LPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLC 468
            +    +    GS   +    PK     + + GR    + S++A+ P    +++   P  
Sbjct: 486 RRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS-PSPRKRQKETSPRG 544

Query: 469 QAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEP 528
           +       +SP+                   P P              T+R        P
Sbjct: 545 RRR-----RSPS-------------------PPP--------------TRRRRS-----P 561

Query: 529 TPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSK--A 586
           +P PPP  ++ P   P R + + P +++ P    + S P+  + SP     SP P +  A
Sbjct: 562 SPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSP-RRYSPPIQRRYSP-----SPPPKRRTA 615

Query: 587 SPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPAT----PKVKSGVRR- 641
           SP   P R + PS             P K      PPP+   +P T    P + S  R+ 
Sbjct: 616 SPPPPPKRRASPSP------------PPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKG 663

Query: 642 AEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVV 701
           + P+    +A   +P+  +      +P +   S SP  +     SS     S S  T  +
Sbjct: 664 SSPSRSTREA--RSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPI 721

Query: 702 QQEVEQLDSAGVTGPHPPSPSEIHKVGSS 730
           ++     +   +     PSP  + +V SS
Sbjct: 722 RRVSRTPEPKKIKKAASPSPQSVRRVSSS 750



 Score = 63.2 bits (152), Expect = 5e-09
 Identities = 138/645 (21%), Positives = 215/645 (33%), Gaps = 101/645 (15%)

Query: 965  ESLTGSPEDRS---RGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQ 1021
            +S + SP  RS   R E   +   S    T   SP+     +E +   P    +++E   
Sbjct: 176  KSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSV 235

Query: 1022 QRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEEL 1081
            Q +A   S    +P  E   E +E   E+   +E+EK +   + R RS +R   R +   
Sbjct: 236  Q-EATSTSDILKVPKPEPIPEPKEPSPEKNSKKEKEKEKTRPRSRSRSKSRSRTRSRSPS 294

Query: 1082 RAQ-RRRERSK---------------------TPPSNLSPIEDASPTEELRQAAEMEELH 1119
              + RRR RS+                     TPP  + P     P    R  + +    
Sbjct: 295  HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPP-----PPRHRRSRSPVRRRR 349

Query: 1120 RSSCS-EYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTET--PSGSSTTPS 1176
            RSS S   S S S  S + +    P +   S          S   P     PS  +T P 
Sbjct: 350  RSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRRHRPSPPATPPP 409

Query: 1177 SGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDRE 1236
              R   + +++      +  +     G+ +G    H G  +   P         + ++ E
Sbjct: 410  KTRHSPTPQQSNRTRKSRVSV---SPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESE 466

Query: 1237 YGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFA----EDKKKEKQFLN 1292
              +  + AA  +            +Q  +   R  Q SS D   +    +++ K     N
Sbjct: 467  EDKGGKMAAADS------------VQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKN 514

Query: 1293 AE-----------SAYMDPMKQNG----------GPLTPGT----SPTQLAAPVSFSTPT 1327
             E           SA   P K+             P  P T    SP+    P    TPT
Sbjct: 515  GEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPT 574

Query: 1328 SSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVA 1387
                      P  R      +    P++   SP+ P           +  P  P     +
Sbjct: 575  PPPRRR-TPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRR-------TASPPPPPKRRAS 626

Query: 1388 PCPAGLPRGYMTP-----ASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGL 1442
            P P    R   +P     +SP    RSPS SS  H  G SP+ +   +++   P      
Sbjct: 627  PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSK-HRKGSSPSRSTREARSPQ-PNKRHSP 684

Query: 1443 AAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSP----PLSPSSPSESPTFSPGKMGP 1498
            +   RA +          G +  P R  S   S+ P      +P         SP     
Sbjct: 685  SPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSV 744

Query: 1499 RATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTP 1543
            R  +   + + SP PA+  P +P    PSP+ +Q   T   P+ P
Sbjct: 745  RRVSSSRSVSGSPEPAAKKPPAP----PSPVQSQSPSTNWSPAVP 785



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 139/668 (20%), Positives = 217/668 (32%), Gaps = 104/668 (15%)

Query: 27  PGPGPGAG-KPPSAPAGGGQL--PAAGAARSTA-VPPVPGPGPGPGPG-PGPGSTSRRLD 81
           P P P    K P  P    ++  P+   A ST+ +  VP P P P P  P P   S++  
Sbjct: 210 PSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNSKKEK 269

Query: 82  PKEPLG-NQRAASPTPKQASATTPGHESPR---ETRAQGPAGQEADGPRRTLQVDSRT-- 135
            KE      R+ S +  +  + +P H  PR    +R++  + +    PRR      RT  
Sbjct: 270 EKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPP 329

Query: 136 --------QRSGRSP---------SVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDL 178
                    R  RSP         S+S    S+ +S    P   P P  T  P  KT  L
Sbjct: 330 RRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKP-PKRTSSPPRKTRRL 388

Query: 179 TSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKS 238
           + + S P                   P+P  T   +                +  P+  +
Sbjct: 389 SPSASPPRRR--------------HRPSPPATPPPK-------------TRHSPTPQQSN 421

Query: 239 QQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPP- 297
           + +    ++SP  +  K    K  ++R      P+P  R+ E + +    G   AAA   
Sbjct: 422 RTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKP--RKVELSESEEDKGGKMAAADSV 479

Query: 298 EVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASL 357
           +  R   +  Q +   +        E P +S              + G  G+      S 
Sbjct: 480 QQRRQYRRQNQQSSSDSGSSSSSEDERPKRS------------HVKNGEVGRRRRHSPSR 527

Query: 358 LTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPG 417
               S     Q E   +G+   S   P      +   A P      P P P     + P 
Sbjct: 528 SASPSP-RKRQKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPP 586

Query: 418 ARMGPGS---GPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNV 474
            R  P      P    +   +  PK   A      K  A P   PK R           V
Sbjct: 587 RRRSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRR-----------V 635

Query: 475 GSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPP 534
               P    +    + +  +L   +       ++     + Q  +    S   P P  P 
Sbjct: 636 SHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS---PRPRAPQ 692

Query: 535 TSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLR 594
           TS  PP     R + +SP +++ P    +P   +     P   K +  PS  S +    R
Sbjct: 693 TSSSPP--PVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVR----R 746

Query: 595 ASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPE 654
            S       S +    + P    P+    P T  +PA P     V++A+  TP     P 
Sbjct: 747 VSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP-----VKKAKSPTP----SPS 797

Query: 655 APKGGEAE 662
            P+  + E
Sbjct: 798 PPRNSDQE 805



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 132/636 (20%), Positives = 211/636 (33%), Gaps = 70/636 (11%)

Query: 3288 EEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARV--EKYGPGPMGPKHPS 3345
            +++ ++D  D   K       E +  P        S  R  + V  E+       P+H +
Sbjct: 146  KQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRT 205

Query: 3346 KSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLA-----SYPPPAVSSSLVSR 3400
            KS +P+    K+ K  +        K   ++EA      L        P P   S   + 
Sbjct: 206  KSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPSPEKNS 265

Query: 3401 GRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAY-------SGEK 3453
             ++ + E T    ++  + +      S       R +   SRS +P          S  +
Sbjct: 266  KKEKEKEKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRR 325

Query: 3454 LSSHDFSGWGKGYEREREAVERLQK--AGPKPSSLSMAHSRVRPPMRSQASEEESP---- 3507
             +          + R R  V R ++  A    SS S + SR R P +       SP    
Sbjct: 326  RTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKT 385

Query: 3508 --VSPLG-------RPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEG 3558
              +SP         RP P   P PP     P    S+     +  V  G  +    + +G
Sbjct: 386  RRLSPSASPPRRRHRPSPPATP-PPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKG 444

Query: 3559 YILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYH 3618
                +S           L + E D   K   A S + R         SS   G +  S  
Sbjct: 445  TEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSE- 503

Query: 3619 DYDEPPEEGLWPHDEGG------PGRHASAKEHRHGDHGRHSGRHT---GEEPGRRAAKP 3669
              DE P+     + E G      P R AS    +        GR        P RR   P
Sbjct: 504  --DERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSPPPTRRRRSP 561

Query: 3670 HARDLGRHEARPHSQPSS-APAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQA 3728
                  R    P   P    P+ P + +   PS   YS P +        S S    R+ 
Sbjct: 562  SPAPPPRRRRTPTPPPRRRTPSPPPRRRS--PSPRRYSPPIQ-----RRYSPSPPPKRRT 614

Query: 3729 HSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQ 3788
             S P   + +A P   P+ +   + P  Q+S   + R+ PS ++  +  +   +     +
Sbjct: 615  ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREAR 674

Query: 3789 PPQQALTQARLQQQSQPTTRGSAP-----AASQPAGKPQPGPST------ATGPQP---- 3833
             PQ     +   +   P T  S P     A+S P  +  P PST      +  P+P    
Sbjct: 675  SPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIK 734

Query: 3834 ----AGPPRAEQTNGSKGTAKAPQ-QGRAPQAQPAP 3864
                  P    + + S+  + +P+   + P A P+P
Sbjct: 735  KAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSP 770



 Score = 56.6 bits (135), Expect = 5e-07
 Identities = 146/725 (20%), Positives = 238/725 (32%), Gaps = 139/725 (19%)

Query: 999  LSSLEEDSDSSPSRRQRL--EEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQ 1056
            L S +E+    PS    L  EE KQ++  + +     L +++   E+++ R++EE    +
Sbjct: 109  LLSAQENIAGIPSAFLELKKEEIKQRQIEQEK-----LASMKKQDEDKDKRDKEEKESSR 163

Query: 1057 EKM-REVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEM 1115
            EK  R    +R +S +   RR    +R +R+R  S++P                      
Sbjct: 164  EKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSP---------------------- 201

Query: 1116 EELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTP 1175
               HR+     SP+P    +   L     ++ +   +    T   L  P   P      P
Sbjct: 202  --RHRTKSRSPSPAPEKKEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEP 259

Query: 1176 SSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDR 1235
            S  +   S +E  +E  R     + +      +R P       T PR         +  R
Sbjct: 260  SPEK--NSKKEKEKEKTRPRSRSRSKSRSRTRSRSP-----SHTRPR-----RRHRSRSR 307

Query: 1236 EYGQAAQPAAEGTPASLGAAVYEEI-----LQTSQSIVRMRQASSRDLAFAEDKKKEKQF 1290
             Y    +P+    P+         +      + S+S VR R+ SS  L+ +       + 
Sbjct: 308  SYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSR- 366

Query: 1291 LNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKET 1350
              + S    P K+   P                                 R T+  +   
Sbjct: 367  --SRSPPKKPPKRTSSP--------------------------------PRKTRRLSPSA 392

Query: 1351 QDPLKLH--SSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSER 1408
              P + H  S PA+P   ++    P        +  +V+P   G   G +T         
Sbjct: 393  SPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSP---GRTSGKVTKHKGTEKRE 449

Query: 1409 SPSPSSTAHSYGHSPTTANYGS---------------QTEDLPQAPSGLAAAGRAAREKP 1453
            SPSP+        S +  + G                +      + SG +++    R K 
Sbjct: 450  SPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKR 509

Query: 1454 LSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAP 1513
                +GE G     R +S   S+SP         SP     +  P        ++PSPAP
Sbjct: 510  SHVKNGEVGR---RRRHSPSRSASPSPRKRQKETSPR-GRRRRSPSPPPTRRRRSPSPAP 565

Query: 1514 ASDMPRSPGAP----TPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITL-------- 1561
                 R+P  P    TPSP   + + +P R S P  + +  S   P    T         
Sbjct: 566  PPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPP--IQRRYSPSPPPKRRTASPPPPPKR 623

Query: 1562 -ASDASSQTRMVHASASTSPLCSPTETQPTT---------HGYSQTTPPSVSQLPPEPPG 1611
             AS +    R V  S       SP   + +             S++T  + S  P +   
Sbjct: 624  RASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHS 683

Query: 1612 PPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTA 1671
            P   PR P   +  P    G  + P       R S  P T  +    RTP      ++ A
Sbjct: 684  PSPRPRAPQTSSSPPPVRRGASSSPQR-----RQSPSPSTRPIRRVSRTPEPK--KIKKA 736

Query: 1672 VKPTP 1676
              P+P
Sbjct: 737  ASPSP 741



 Score = 50.4 bits (119), Expect = 3e-05
 Identities = 108/526 (20%), Positives = 177/526 (33%), Gaps = 89/526 (16%)

Query: 33  AGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAA 92
           +G   S+ +   + P     + T+ PP       P   P P    R   P  P    R  
Sbjct: 356 SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASP-PRRRHRPSPPATPPPKTRH- 413

Query: 93  SPTPKQASAT-------TPGHESPRETRAQGPAGQE----ADGPRRTLQVDSRTQRSGRS 141
           SPTP+Q++ T       +PG  S + T+ +G   +E    A  PR+    +S   + G+ 
Sbjct: 414 SPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKM 473

Query: 142 PSV----------------SPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQP 185
            +                 S D GS+ +S    P+ + + +  +    + S   S    P
Sbjct: 474 AAADSVQQRRQYRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSP 533

Query: 186 NFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQ----- 240
                 Q       +   +P+P  T+ +         +R      T  PR ++       
Sbjct: 534 RKR---QKETSPRGRRRRSPSPPPTRRRRSPSPAPPPRRR--RTPTPPPRRRTPSPPPRR 588

Query: 241 -----QLHSPAL----SPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETA--------- 282
                + +SP +    SP+  P ++    P   + R    P P  R + +          
Sbjct: 589 RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPV 648

Query: 283 ---RATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGAT 339
              R+ S+    +  + P       + PQP K  +  PRP    AP  S++  P   GA+
Sbjct: 649 TKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP---RAPQTSSSPPPVRRGAS 705

Query: 340 EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPA-PSKGTPKIVFNDASKEAGPK 398
              Q   +        S  T+    +S  PE     + A PS  + + V +  S    P+
Sbjct: 706 SSPQRRQS-------PSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPE 758

Query: 399 PLGSGPGPGPAPGAKTEPGARMGPG-------------SGPGALPKTGGTTSPKHGRAEH 445
           P    P   P+P     P     P              S P    + GG    K  + + 
Sbjct: 759 PAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPSPSPPRNSDQEGGGKKKKKKKDKK 818

Query: 446 QAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQ 491
               K   K K   KE+A+     A +     +PA     TT   Q
Sbjct: 819 HKKDKKHKKHKKHKKEKAVAAAAAAAV-----TPAAIAAATTTLAQ 859



 Score = 49.3 bits (116), Expect = 8e-05
 Identities = 50/205 (24%), Positives = 78/205 (38%), Gaps = 27/205 (13%)

Query: 3662 PGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDS 3721
            P +R A P      R    P  +  S+P   ++         + S PSR++        +
Sbjct: 620  PPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPN 679

Query: 3722 KKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ 3781
            K+ S      P A Q+ + P   P ++ R A+  PQ+ QSPS    P    SR P+ ++ 
Sbjct: 680  KRHSPSPR--PRAPQTSSSP---PPVR-RGASSSPQRRQSPSPSTRPIRRVSRTPEPKKI 733

Query: 3782 QQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQP----GPST---------- 3827
            ++     P        R    S+  +    PAA +P   P P     PST          
Sbjct: 734  KKAASPSP-----QSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKK 788

Query: 3828 --ATGPQPAGPPRAEQTNGSKGTAK 3850
              +  P P+ P  ++Q  G K   K
Sbjct: 789  AKSPTPSPSPPRNSDQEGGGKKKKK 813



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 57/306 (18%), Positives = 106/306 (34%), Gaps = 43/306 (14%)

Query: 3605 SSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGR 3664
            SS +KR  +R         P     P     P R    + H      R   R     P +
Sbjct: 161  SSREKRERSRSPRRRKSRSPS----PRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAPEK 216

Query: 3665 RAAKPHARDLGRHEARPHSQPSSAPA----------MPKKGQPGYPSSAEYSQPSRASSA 3714
            +   P   +       P  Q +++ +          +P+  +P  P      +  +  + 
Sbjct: 217  KEKTPELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-PEKNSKKEKEKEKTR 275

Query: 3715 YHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAA-- 3772
                S SK  SR     P+  + +   +++ +    +  P P++  SP  R  P      
Sbjct: 276  PRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPP 335

Query: 3773 -----SRQPQTQQQQQGLGLQPPQQALTQARLQ--------QQSQPT--TRGSAPAASQP 3817
                 SR P  ++++    L     + + +R +        + S P   TR  +P+AS P
Sbjct: 336  PRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPP 395

Query: 3818 AGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRA-----------PQAQPAPGP 3866
              + +P P     P+    P  +Q+N ++ +  +   GR             +  P+P P
Sbjct: 396  RRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAP 455

Query: 3867 GPAGVK 3872
             P  V+
Sbjct: 456  KPRKVE 461



 Score = 45.4 bits (106), Expect = 0.001
 Identities = 67/300 (22%), Positives = 104/300 (34%), Gaps = 60/300 (20%)

Query: 17  PPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGST 76
           PP      P P P P   + P+ P            R T  PP     P P     P   
Sbjct: 553 PPTRRRRSPSPAPPPRRRRTPTPPP----------RRRTPSPPPRRRSPSPRRYSPP--I 600

Query: 77  SRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGP---RRTLQVDS 133
            RR  P  P   +R ASP P      +P    P+   +  P  ++   P   RR+  + S
Sbjct: 601 QRRYSPSPP-PKRRTASPPPPPKRRASPS-PPPKRRVSHSPPPKQRSSPVTKRRSPSLSS 658

Query: 134 RTQRSGRSPSVSPDRGSTPT-----SPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFN 188
           +  R G SPS S     +P      SP   P+ AP  SS+  P+ + +  +S+P +    
Sbjct: 659 K-HRKGSSPSRSTREARSPQPNKRHSPSPRPR-APQTSSSPPPVRRGA--SSSPQRRQ-- 712

Query: 189 TCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALS 248
                          +P+P    ++              +  T  P+   +    SP   
Sbjct: 713 ---------------SPSPSTRPIRR-------------VSRTPEPKKIKKAASPSPQSV 744

Query: 249 PAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQ 308
              S ++   G P+    + P  P P   Q+ +   +      +A +P      SP PP+
Sbjct: 745 RRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTP----SPSPPR 800



 Score = 43.5 bits (101), Expect = 0.004
 Identities = 83/409 (20%), Positives = 136/409 (33%), Gaps = 57/409 (13%)

Query: 978  EHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTI 1037
            +H  T    +PS         LS  EED     +    +++ +Q R+   +S        
Sbjct: 441  KHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQS-------- 492

Query: 1038 EDSSEEEELREEEELLREQEKMREVEQQRIRSTARKT-----RRDKEELRAQRRRERSKT 1092
               S      E+E   R   K  EV ++R  S +R       +R KE     RRR     
Sbjct: 493  SSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRGRRRRSPSP 552

Query: 1093 PPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSE 1152
            PP+        +P    R+        R      +PSP            P R   S   
Sbjct: 553  PPTRRRRSPSPAPPPRRRRTPTPPPRRR------TPSPP-----------PRRRSPSPRR 595

Query: 1153 YNLPTFMSLYSPTETPSGSSTTP---------SSGRPLKSAEEAYEEMMRKAELLQRQQG 1203
            Y+ P     YSP+  P   + +P          S  P +    +     R + + +R+  
Sbjct: 596  YS-PPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSP 654

Query: 1204 QAAGARGPHGGPSQPT-GPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQ 1262
              +        PS+ T   R     +    + R   +A Q ++   P   GA+   +  Q
Sbjct: 655  SLSSKHRKGSSPSRSTREARSPQPNKRHSPSPRP--RAPQTSSSPPPVRRGASSSPQRRQ 712

Query: 1263 TSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVS 1322
            +     R  +  SR     + KK       +          +G P      P    +PV 
Sbjct: 713  SPSPSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQ 772

Query: 1323 FSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIG 1371
              +P+++ S      P V V     K+ + P     SP+ P ++ +E G
Sbjct: 773  SQSPSTNWS------PAVPV-----KKAKSPT---PSPSPPRNSDQEGG 807



 Score = 40.0 bits (92), Expect = 0.046
 Identities = 152/712 (21%), Positives = 237/712 (33%), Gaps = 117/712 (16%)

Query: 2600 RRRRARRSADCSVQTDDEDSAEWEQPV----RRRRSRLPRHSDSGSDSKHDATASSSSAA 2655
            R+    + A    Q +D+D  + E+      +R RSR PR   S S S            
Sbjct: 134  RQIEQEKLASMKKQDEDKDKRDKEEKESSREKRERSRSPRRRKSRSPSP----------- 182

Query: 2656 ATVRAMSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGES 2715
               R  SS          V+ E  +    SP  H T +  P         APEK  +   
Sbjct: 183  ---RRRSS---------PVRRERKRSHSRSPR-HRTKSRSPS-------PAPEKKEKTPE 222

Query: 2716 LACQTEPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLP 2775
            L    EP  +   V  P +   T+ S  L   ++  P P+   E K+P P +   +    
Sbjct: 223  LP---EPSVK---VKEPSVQEATSTSDIL---KVPKPEPIP--EPKEPSPEKNSKKEKEK 271

Query: 2776 PESLSQLVSRQPPKSPQVLYSP--VSPLSPHRLLDTSFASSERLNKAHVSPQKHFTADSA 2833
             ++  +  SR   +S     SP    P   HR    S++   R      SP++      +
Sbjct: 272  EKTRPRSRSRSKSRSRTRSRSPSHTRPRRRHRSRSRSYSPRRR-----PSPRRR----PS 322

Query: 2834 LRQQTLPRPMKTLQRSLSDPKPLSPTAEESAKERFSLYQHQGGLGSQVSALPP------- 2886
             R++T PR M    R      P+      SA    SL        S  S  PP       
Sbjct: 323  PRRRTPPRRMPPPPRHRRSRSPVRRRRRSSA----SLSGSSSSSSSSRSRSPPKKPPKRT 378

Query: 2887 NSLVRKVKRTLPSP-PPEEAHLPLAGQASPQL--YAASLLQRGLTGPTTVPATKASLLRE 2943
            +S  RK +R  PS  PP   H P      P    ++ +  Q   T  + V  +      +
Sbjct: 379  SSPPRKTRRLSPSASPPRRRHRPSPPATPPPKTRHSPTPQQSNRTRKSRVSVSPGRTSGK 438

Query: 2944 LDRDLRLVEHESTKLRKK--QAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPP 3001
            + +     + ES     K  + EL E E++   K+   +    +R+      +   D   
Sbjct: 439  VTKHKGTEKRESPSPAPKPRKVELSESEEDKGGKMAAADSVQQRRQYRRQNQQSSSDSGS 498

Query: 3002 LRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAP 3061
                 + R   S  +  ++  +   +P+      P       +P G    ++ R   P P
Sbjct: 499  SSSSEDERPKRSHVKNGEVGRRRRHSPSRSASPSPRKRQKETSPRG----RRRRSPSPPP 554

Query: 3062 QYSAGSGGP--------TQNGFPAHQAPTYPGPSTYPAPA-FPPGASYPAEPGLPNQQAF 3112
                 S  P        T    P  + P+ P     P+P  + P       P  P ++  
Sbjct: 555  TRRRRSPSPAPPPRRRRTPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRYSPSPPPKRRT 614

Query: 3113 R----PTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPTNYEVIASPV 3168
                 P    A  +P P  + +  P P    +P+ K R  SL+   +K            
Sbjct: 615  ASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRK------------ 662

Query: 3169 VPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSDSHYTSLEQNVP 3228
                S+PS ++    +          P  PRA      S SP P     S      Q+  
Sbjct: 663  ---GSSPSRSTREARSPQPNKRHSPSPR-PRA---PQTSSSPPPVRRGASSSPQRRQSPS 715

Query: 3229 RNYVMIDDIS-----ELTKDSTSTAPDSQRLEPLGPGSSGRP---GKEPGEP 3272
             +   I  +S     +  K + S +P S R        SG P    K+P  P
Sbjct: 716  PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAP 767



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 156/775 (20%), Positives = 266/775 (34%), Gaps = 122/775 (15%)

Query: 2369 QEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQ 2428
            QE +  +    +EL+K  +++ Q ++E+E++   + ++E++   +R+ +E ++       
Sbjct: 113  QENIAGIPSAFLELKK-EEIK-QRQIEQEKLASMKKQDEDK--DKRDKEEKES------S 162

Query: 2429 QQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQKQRQKAPFPAACEAPGRGP 2488
            +++ ER      ++ +    R +   +++ +++   +    + + ++P PA  E   + P
Sbjct: 163  REKRERSRSPRRRKSRSPSPRRRSSPVRRERKRSHSRSPRHRTKSRSPSPAP-EKKEKTP 221

Query: 2489 PLAAAELAQNGQYWPPLTHAA-FIAMAGPEGLGQPREPVLHRGLPSSASDMSLQTEEQWE 2547
             L    +          T  +  + +  PE + +P+EP      P   S    + E+   
Sbjct: 222  ELPEPSVKVKEPSVQEATSTSDILKVPKPEPIPEPKEPS-----PEKNSKKEKEKEKTRP 276

Query: 2548 ASRSGIKKRHSMPRLRDACELESGTEPCVVRRIADSSVQTDDEDGESRYLLSRRRRARRS 2607
             SRS  K R      R      S T P    R    S          R    RRR   R 
Sbjct: 277  RSRSRSKSRS-----RTRSRSPSHTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPR- 330

Query: 2608 ADCSVQTDDEDSAEWEQPVRRRRSRLP----RHSD---SGSDSKHDATASSSSAAATVRA 2660
                             P R RRSR P    R S    SGS S   ++ S S      + 
Sbjct: 331  -------------RMPPPPRHRRSRSPVRRRRRSSASLSGSSSSSSSSRSRSPPKKPPKR 377

Query: 2661 MSSVGIQTISDCSVQTEPDQLPRVSPAIHITAATDPKVEIVRYISAPEKTGRGESLACQT 2720
             SS   +T       + P +  R SP     A   PK    R+   P+++ R        
Sbjct: 378  TSSPPRKTRRLSPSASPPRRRHRPSP----PATPPPK---TRHSPTPQQSNRTRKSRVSV 430

Query: 2721 EPDGQAQGVAGPQLVGPTAISPYLPGIQIVTPGPLGRFEKKKPDPLEIGYQAHLPPESLS 2780
             P G+  G            SP        +P P       KP  +E+          ++
Sbjct: 431  SP-GRTSGKVTKHKGTEKRESP--------SPAP-------KPRKVELSESEEDKGGKMA 474

Query: 2781 QLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASSERLNKAHV-----------SPQKHFT 2829
               S Q  +     Y   +  S      +S +  ER  ++HV           SP +  +
Sbjct: 475  AADSVQQRRQ----YRRQNQQSSSDSGSSSSSEDERPKRSHVKNGEVGRRRRHSPSRSAS 530

Query: 2830 ADSALRQ-QTLPRPMKTLQRSLSDP---KPLSPTAEESAKERFSLYQHQGGLGSQVSALP 2885
                 RQ +T PR  +  +RS S P   +  SP+     + R            +    P
Sbjct: 531  PSPRKRQKETSPRGRR--RRSPSPPPTRRRRSPSPAPPPRRR------------RTPTPP 576

Query: 2886 PNSLVRKVKRTLPSPPPEEAHLPLAGQASPQL---YAAS-LLQRGLTGPTTVPATKASLL 2941
            P       +R  PSPPP     P   + SP +   Y+ S   +R    P   P  +AS  
Sbjct: 577  P-------RRRTPSPPPRR-RSPSPRRYSPPIQRRYSPSPPPKRRTASPPPPPKRRAS-- 626

Query: 2942 RELDRDLRLVEHESTKLRKKQAELDEEEKEIDAKLKYLELGITQRKESLAKDRGGRDYPP 3001
                   R V H     ++           + +K +         +E+ +     R  P 
Sbjct: 627  -PSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSSKHRKGSSPSRSTREARSPQPNKRHSPS 685

Query: 3002 LRGLGEHRDYLSDSELNQLRLQGCTTPAGQFVDFPATAAAPATPSGPTAFQQPRFQPPAP 3061
             R     R   + S    +R    ++P  +    P+T         P   +  +   P+P
Sbjct: 686  PR----PRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKKAASPSP 741

Query: 3062 Q-YSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGASYPAEPGLPNQQAFRPT 3115
            Q     S   + +G P   A   P P   P+P      S    P +P ++A  PT
Sbjct: 742  QSVRRVSSSRSVSGSPEPAAKKPPAP---PSPVQSQSPSTNWSPAVPVKKAKSPT 793



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 22/112 (19%), Positives = 44/112 (39%), Gaps = 4/112 (3%)

Query: 2260 RYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAI 2319
            R P P +   A+S  P          + + +P       P  P     + P    +PA  
Sbjct: 726  RTPEPKKIKKAASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVP 785

Query: 2320 KEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPGFEKEEASQEERQRKQQEQ 2371
             + A +P P+P     PP ++   GG     +   +K +  ++ ++ K+ ++
Sbjct: 786  VKKAKSPTPSP----SPPRNSDQEGGGKKKKKKKDKKHKKDKKHKKHKKHKK 833



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 33/146 (22%), Positives = 56/146 (38%), Gaps = 21/146 (14%)

Query: 15  PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
           P P     P P P     +  PP    G    P    + S +  P+              
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPI-------------R 722

Query: 75  STSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSR 134
             SR  +PK+    ++AASP+P+     +    S   + +  PA ++   P   +Q  S+
Sbjct: 723 RVSRTPEPKK---IKKAASPSPQSVRRVS---SSRSVSGSPEPAAKKPPAPPSPVQ--SQ 774

Query: 135 TQRSGRSPSVSPDRGSTPTSPYSVPQ 160
           +  +  SP+V   +  +PT   S P+
Sbjct: 775 SPSTNWSPAVPVKKAKSPTPSPSPPR 800


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 76.3 bits (186), Expect = 6e-13
 Identities = 107/427 (25%), Positives = 131/427 (30%), Gaps = 72/427 (16%)

Query: 3497 MRSQASEEESP---------VSPLGRPRPAGGPLPPGGDTCP--QFCSSHSMPDVQEHVK 3545
            +    S+EESP           P G  +P G P PPG    P  Q  +    P       
Sbjct: 19   LNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKP 78

Query: 3546 DGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSS 3605
             GP      + +G                   Q      DK R  RS   +  G      
Sbjct: 79   QGPPPQGGNKPQG------------PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPP-QG 125

Query: 3606 SSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRR 3665
             +Q +GP          PP+ G  P     PG     K       G +  R +   PG+ 
Sbjct: 126  GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPG-----KPQGPPPQGDNKSRSSRSPPGKP 180

Query: 3666 AAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQ-PSRASSAYHHASDSKKG 3724
               P          +  +QP   P  P K Q   P      Q P                
Sbjct: 181  QGPP---------PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNK 231

Query: 3725 SRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQG 3784
            S+ A S P   Q    PQ   Q QG    PG  Q   P     P G     P    + QG
Sbjct: 232  SQSARSPPGKPQGPP-PQGGNQPQGPPPPPGKPQGPPPQGGNKPQG-----PPPPGKPQG 285

Query: 3785 LGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
                PP Q  +++R              ++  P GKPQ GP    G QP GPP       
Sbjct: 286  ----PPPQGGSKSR--------------SSRSPPGKPQ-GPPPQGGNQPQGPPPPP---- 322

Query: 3845 SKGTAKAPQQGRAPQAQPAPG----PGPAGVKAGARPGGTPGAPAGQPGADGESVFSKIL 3900
             K     PQ G  PQ  P PG    P P G          PG P G P  +G +      
Sbjct: 323  GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP 382

Query: 3901 PGGAAEQ 3907
            P G   Q
Sbjct: 383  PAGGNPQ 389



 Score = 75.5 bits (184), Expect = 1e-12
 Identities = 105/425 (24%), Positives = 136/425 (32%), Gaps = 83/425 (19%)

Query: 10  GAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGP 69
           G   GP P GG  P    GP P  GKP   P  GG  P          PP PG   GP P
Sbjct: 55  GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQG--------PPPPGKPQGPPP 103

Query: 70  GPGPGSTSRRLDPKEPLG-----NQRAASPTPKQASATTPGHESPRETRAQGPAGQEADG 124
             G  S S R  P +P G       +   P P       P  +   + +   P G+   G
Sbjct: 104 -QGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QG 161

Query: 125 PRRTLQVDSRTQRS--GRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTP 182
           P       SR+ RS  G+     P  G+ P  P       P P     P  +  +    P
Sbjct: 162 PPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGP------PPPPGKPQGPPPQGGNKPQGP 215

Query: 183 SQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQL 242
             P             +Q   +P                     G      P+  +Q Q 
Sbjct: 216 PPPGKPQGPPPQGDNKSQSARSPP--------------------GKPQGPPPQGGNQPQG 255

Query: 243 HSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQA------ETARATSVPGPAQAAAP 296
             P       P  +P G P Q  ++  G P PG  Q         +R++  P P +   P
Sbjct: 256 PPP-------PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSP-PGKPQGP 307

Query: 297 PEVGRVSPQ--PPQPTKPSTAEPR---PPAGEAPAKSATAVPAGLGATEQTQEGLTGKLF 351
           P  G   PQ  PP P KP    P+    P G  P       P   G+  ++     GK  
Sbjct: 308 PPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQ 367

Query: 352 GLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPG 411
           G               Q   + QG P P+ G P+        +A P     GP   P  G
Sbjct: 368 G------------PPQQEGNNPQGPPPPAGGNPQ------QPQAPPAGQPQGPPRPPQGG 409

Query: 412 AKTEP 416
             + P
Sbjct: 410 RPSRP 414



 Score = 72.8 bits (177), Expect = 6e-12
 Identities = 111/469 (23%), Positives = 145/469 (30%), Gaps = 108/469 (23%)

Query: 6   SLEGGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGP 65
           SL  G   G  P GG  P   P P    GKP   P  GG  P             P P P
Sbjct: 30  SLIAGNPQGAPPQGGNKPQGPPSP---PGKPQGPPPQGGNQPQG-----------PPPPP 75

Query: 66  GPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGP 125
           G   GP P             GN+    P P +     P  +  R  R+  P   +   P
Sbjct: 76  GKPQGPPPQG-----------GNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPP 123

Query: 126 RRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQP 185
           +   Q        G+     P  G+ P  P       P P     P  +  + + +   P
Sbjct: 124 QGGNQPQGPPPPPGKPQGPPPQGGNKPQGP-------PPPGKPQGPPPQGDNKSRSSRSP 176

Query: 186 NFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSP 245
                                                    G      P+  +Q Q   P
Sbjct: 177 P----------------------------------------GKPQGPPPQGGNQPQGPPP 196

Query: 246 ALSPAHSPAKQ----PLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGR 301
                  P  Q    P G P   + +GP  P  G  ++++AR  S PG  Q   PP  G 
Sbjct: 197 PPGKPQGPPPQGGNKPQGPPPPGKPQGP--PPQGDNKSQSAR--SPPGKPQG--PPPQGG 250

Query: 302 VSPQ--PPQPTKPSTAEPR---PPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGAS 356
             PQ  PP P KP    P+    P G  P       P   G+  ++     GK  G    
Sbjct: 251 NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQG---- 306

Query: 357 LLTQASTLMSVQPEADTQGQ-PAPSKGTPK-IVFNDASKEAGPKPLGSGPGPGPAPGAKT 414
                       P+   Q Q P P  G P+       +K  GP P G   GP P  G+K+
Sbjct: 307 ----------PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKS 356

Query: 415 EPGARMGPGSGPGALPKTGGTTS---PKHGRAEHQAASKAAAKPKTMPK 460
              AR  PG   G   + G       P  G    Q  +  A +P+  P+
Sbjct: 357 R-SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPR 404



 Score = 71.6 bits (174), Expect = 1e-11
 Identities = 110/441 (24%), Positives = 138/441 (31%), Gaps = 78/441 (17%)

Query: 241 QLHSPALSPAHSPAKQPLG--KPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPE 298
           Q  SP+L   +     P G  KP    S  PG PQ    Q         P P +   PP 
Sbjct: 25  QEESPSLIAGNPQGAPPQGGNKPQGPPSP-PGKPQGPPPQGGNQPQGPPPPPGKPQGPPP 83

Query: 299 VGRVSPQ-PPQPTKPSTAEPRPPAGEAPAKSATAVPAGL----GATEQTQEGLTGKLFGL 353
            G   PQ PP P KP    P+     +P +S    P G     G   Q      GK  G 
Sbjct: 84  QGGNKPQGPPPPGKPQGPPPQGDKSRSP-RSPPGKPQGPPPQGGNQPQGPPPPPGKPQGP 142

Query: 354 GASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAK 413
                   +      P    QG P       +   +   K  GP P G     GP P   
Sbjct: 143 PPQ---GGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPP--- 196

Query: 414 TEPGARMGP----GSGPGALPKTGGTTS-PKHGRAEHQAASKAAAKPKTMPKERAICPLC 468
             PG   GP    G+ P   P  G     P  G  + Q+A     KP+  P +       
Sbjct: 197 -PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQ------- 248

Query: 469 QAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEP 528
                 G   P                 G  P P   +               +G     
Sbjct: 249 ------GGNQPQ----------------GPPPPPGKPQGPP-----------PQGGNKPQ 275

Query: 529 TPLPPPTSQQPPV--GAPHRASGTSPLKQKG--PQGLGQPSGPLPAKASPL------STK 578
            P PP   Q PP   G+  R+S + P K +G  PQG  QP GP P    P         K
Sbjct: 276 GPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNK 335

Query: 579 ASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSG 638
               P    PQ  P +    S++  S   K    P +    P+ PP   P    P+    
Sbjct: 336 PQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPP--PPAGGNPQQPQA 393

Query: 639 VRRAEPATPVVKAVPEAPKGG 659
               +P  P     P  P+GG
Sbjct: 394 PPAGQPQGP-----PRPPQGG 409



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 93/398 (23%), Positives = 125/398 (31%), Gaps = 74/398 (18%)

Query: 253 PAKQPLGKPDQERSRGPGGPQPGSRQA-----ETARATSVPGPAQAAAPPEVGRVSPQ-- 305
           P  +P G P Q  ++  G P PG  Q      + +R+   P P +   PP  G   PQ  
Sbjct: 74  PPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP-PGKPQGPPPQGGNQPQGP 132

Query: 306 PPQPTKPSTAEPR---PPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQAS 362
           PP P KP    P+    P G  P       P       ++     GK  G          
Sbjct: 133 PPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQG---------- 182

Query: 363 TLMSVQPEADTQGQ-PAPSKGTPK-IVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARM 420
                 P+   Q Q P P  G P+       +K  GP P G   GP P    K++  AR 
Sbjct: 183 ----PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQ-SARS 237

Query: 421 GPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPA 480
            PG   G  P+ G          + Q       KP+  P +    P        G   P 
Sbjct: 238 PPGKPQGPPPQGGN---------QPQGPPPPPGKPQGPPPQGGNKPQ-------GPPPPG 281

Query: 481 NYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPP-----PT 535
                              P P    K+          R      G+P   PP     P 
Sbjct: 282 KPQ---------------GPPPQGGSKS----------RSSRSPPGKPQGPPPQGGNQPQ 316

Query: 536 SQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRA 595
              PP G P         K +GP   G+P GP P   S   +  SP      P  +    
Sbjct: 317 GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGNN 376

Query: 596 SEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATP 633
            +    P+    ++ + P   +P   P P     P+ P
Sbjct: 377 PQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414



 Score = 62.0 bits (149), Expect = 1e-08
 Identities = 75/306 (24%), Positives = 95/306 (31%), Gaps = 74/306 (24%)

Query: 10  GAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGP 69
           G   GP P GG  P    GP P  GKP   P  GG  P          PP PG   GP P
Sbjct: 178 GKPQGPPPQGGNQP---QGPPPPPGKPQGPPPQGGNKPQG--------PPPPGKPQGPPP 226

Query: 70  GPGPGSTSRRLDPKEPLG-----NQRAASPTPKQASATTPGHESPRETRAQGPAGQEADG 124
                S S R  P +P G       +   P P       P  +   + +   P G+   G
Sbjct: 227 QGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP-QG 285

Query: 125 PRRTLQVDSRTQRS--GRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTP 182
           P       SR+ RS  G+     P  G+ P  P       P P     P  +  +    P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGP------PPPPGKPQGPPPQGGNKPQGP 339

Query: 183 SQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQL 242
             P                                         G      P+  S+ + 
Sbjct: 340 PPP-----------------------------------------GKPQGPPPQGGSKSR- 357

Query: 243 HSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRV 302
                  A SP  +P G P QE +   G P P     +  +A     P     PP+ GR 
Sbjct: 358 ------SARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411

Query: 303 SPQPPQ 308
           S +PPQ
Sbjct: 412 S-RPPQ 416



 Score = 58.9 bits (141), Expect = 9e-08
 Identities = 86/365 (23%), Positives = 117/365 (32%), Gaps = 36/365 (9%)

Query: 3478 KAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSM 3537
            + G KP           PP   Q  +  SP SP G+P+   GP P GG+  PQ       
Sbjct: 84   QGGNKPQGPPPPGKPQGPP--PQGDKSRSPRSPPGKPQ---GPPPQGGNQ-PQG------ 131

Query: 3538 PDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRH 3597
            P        GP      + +G                          +K R +RS   + 
Sbjct: 132  PPPPPGKPQGPPPQGGNKPQG-----------PPPPGKPQGPPPQGDNKSRSSRSPPGKP 180

Query: 3598 HGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRH 3657
             G       +Q +GP          PP+ G  P     PG+         GD+   S R 
Sbjct: 181  QGPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ--GDNKSQSARS 237

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
               +P  +   P   +  +    P  +P   P        G P   +   P     +   
Sbjct: 238  PPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQ 3777
            +S S  G  Q   GP   Q   +PQ  P   G+   P PQ    P     P       PQ
Sbjct: 296  SSRSPPGKPQ---GPPP-QGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQ 351

Query: 3778 TQQQQQGLGLQP--PQQALTQARLQQQSQPTTRGSAPAASQ--PAGKPQPGPSTATGPQP 3833
               + +     P  PQ    Q     Q  P   G  P   Q  PAG+PQ  P    G +P
Sbjct: 352  GGSKSRSARSPPGKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRP 411

Query: 3834 AGPPR 3838
            + PP+
Sbjct: 412  SRPPQ 416



 Score = 55.1 bits (131), Expect = 1e-06
 Identities = 60/233 (25%), Positives = 78/233 (33%), Gaps = 16/233 (6%)

Query: 527 EPTPLPPPTSQQ--PPVGAPHRASGTSPLKQKG--PQGLGQPSGPLPAKASPL------S 576
           +P   PPP   Q  PP G   R+  + P K +G  PQG  QP GP P    P        
Sbjct: 88  KPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG 147

Query: 577 TKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVK 636
            K    P    PQ  P +    S++  S   K    P +    P+ PP     P  P  +
Sbjct: 148 NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ 207

Query: 637 SGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSE 696
            G +   P  P     P  P+G         P  +     PQ     G    G      +
Sbjct: 208 GGNKPQGPPPPGKPQGP-PPQGDNKSQSARSPPGKPQGPPPQG----GNQPQGPPPPPGK 262

Query: 697 ITGVVQQEVEQLDSAGVTG-PHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKP 748
             G   Q   +       G P  P P    K  SS  P  + QG  P   ++P
Sbjct: 263 PQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQP 315



 Score = 48.1 bits (113), Expect = 2e-04
 Identities = 66/275 (24%), Positives = 91/275 (33%), Gaps = 46/275 (16%)

Query: 1358 SSPASPSSASKEIGMP----FSQGPGTPATTAVAPCPAG--LPRGYMTPASPAGSERSPS 1411
            + P  P    K  G P     S+ P +P      P P G   P+G   P  P G  + P 
Sbjct: 87   NKPQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQG---PPPPPGKPQGPP 143

Query: 1412 PSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAYS 1471
            P       G  P     G   +   ++ S  +  G+     P   +  +G  P P +   
Sbjct: 144  PQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK--- 200

Query: 1472 YFASSSPPLSPSSPSESPTFSPGK-MGPRATAEFSTQ---TPSPAPASDMPR---SPGAP 1524
                  PP   + P   P   PGK  GP    +  +Q   +P   P    P+    P  P
Sbjct: 201  --PQGPPPQGGNKPQGPP--PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGP 256

Query: 1525 TPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCSP 1584
             P P   QG   P   + P+        + P           S++R     +S SP    
Sbjct: 257  PPPPGKPQG-PPPQGGNKPQGPPPPGKPQGP------PPQGGSKSR-----SSRSP---- 300

Query: 1585 TETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVP 1619
                    G  Q  PP     P  PP PPG P+ P
Sbjct: 301  -------PGKPQGPPPQGGNQPQGPPPPPGKPQGP 328



 Score = 46.6 bits (109), Expect = 5e-04
 Identities = 65/262 (24%), Positives = 81/262 (30%), Gaps = 35/262 (13%)

Query: 526 GEPTPLPP-----PTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLP------AKASP 574
           G+P   PP     P    PP G P         K +GP   G+P GP P      +  SP
Sbjct: 55  GKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRSPRSP 114

Query: 575 LSTKASPLPSKAS-PQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPT---- 629
                 P P   + PQ  P    +P   P     K    P   +P   PP     +    
Sbjct: 115 PGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSR 174

Query: 630 -----PATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTG 684
                P  P  + G +   P  P  K     P+GG       KP        PQ     G
Sbjct: 175 SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGG------NKPQGPPPPGKPQGPPPQG 228

Query: 685 YSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPPS-----PSEIHKVGSSMRPLLQAQG 739
              D  S S     G  Q    Q  +     P PP      P +         P  + QG
Sbjct: 229 ---DNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQG 285

Query: 740 LAPSERSKPLSSGTGEEQKQRP 761
             P   SK  SS +   + Q P
Sbjct: 286 PPPQGGSKSRSSRSPPGKPQGP 307



 Score = 46.2 bits (108), Expect = 6e-04
 Identities = 56/230 (24%), Positives = 77/230 (33%), Gaps = 17/230 (7%)

Query: 526 GEPTPLPPPTSQQP--PVGAPHRASGTSPLKQKGPQGL----GQPSGPLPAKASPLSTKA 579
           G P   PP    +P  P   P +  G  P     PQG     G+P GP P   +    K 
Sbjct: 34  GNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN----KP 89

Query: 580 SPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGV 639
              P    PQ  P +  + S++P S   K    P +    P+ PP     P  P  + G 
Sbjct: 90  QGPPPPGKPQGPPPQ-GDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148

Query: 640 RRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITG 699
           +   P  P     P  P+G         P  +     PQ     G    G      +  G
Sbjct: 149 KPQGPPPPGKPQGP-PPQGDNKSRSSRSPPGKPQGPPPQG----GNQPQGPPPPPGKPQG 203

Query: 700 VVQQEVEQLDSAGVTG-PHPPSPSEIHKVGSSMRPLLQAQGLAPSERSKP 748
              Q   +       G P  P P   +K  S+  P  + QG  P   ++P
Sbjct: 204 PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP 253



 Score = 43.9 bits (102), Expect = 0.003
 Identities = 65/284 (22%), Positives = 92/284 (32%), Gaps = 41/284 (14%)

Query: 1358 SSPASPSSASKEIGMP-----FSQGPGTPATTAVAPCPAG--LPRGYMTPASPAGSERSP 1410
            + P  P    K  G P      S+   +P      P P G   P+G   P  P G  + P
Sbjct: 148  NKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQG---PPPPPGKPQGP 204

Query: 1411 SPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRAY 1470
             P       G  P     G   +   ++ S  +  G+     P   +  +G  P P +  
Sbjct: 205  PPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGK-- 262

Query: 1471 SYFASSSPPLSPSSPSESPTFSPGK-MGP---RATAEFSTQTPSPAPASDMPR---SPGA 1523
                   PP   + P   P   PGK  GP     +   S+++P   P    P+    P  
Sbjct: 263  ---PQGPPPQGGNKPQGPP--PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQG 317

Query: 1524 PTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHASASTSPLCS 1583
            P P P   QG   P   + P+        + P           S++R     ++ SP   
Sbjct: 318  PPPPPGKPQG-PPPQGGNKPQGPPPPGKPQGP------PPQGGSKSR-----SARSPPGK 365

Query: 1584 PTETQPTTHGYSQTTPPSVSQLPPEPPGPP-----GFPRVPSAG 1622
            P           Q  PP     P +P  PP     G PR P  G
Sbjct: 366  PQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409



 Score = 41.2 bits (95), Expect = 0.020
 Identities = 55/198 (27%), Positives = 62/198 (31%), Gaps = 32/198 (16%)

Query: 1358 SSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAG--LPRGYMTPASP------AGSERS 1409
            S P  P     + G    QGP  P      P P G   P+G   P  P       GS+  
Sbjct: 237  SPPGKPQGPPPQGGNQ-PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSR 295

Query: 1410 PSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
             S S      G  P   N        P  P G           P    +   G P P + 
Sbjct: 296  SSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQG----------PPPQGGNKPQGPPPPGKP 345

Query: 1470 YSYFASSSPPLSPSSPSESPTFSPGK-MGPRATAEFSTQTPSPAPASDMPRSPGAPTPSP 1528
                    PP    S S S    PGK  GP      + Q P P PA   P+ P AP    
Sbjct: 346  ------QGPPPQGGSKSRSARSPPGKPQGPPQQEGNNPQGPPP-PAGGNPQQPQAPPAGQ 398

Query: 1529 MVAQGTQTP---HRPSTP 1543
               QG   P    RPS P
Sbjct: 399  --PQGPPRPPQGGRPSRP 414



 Score = 38.9 bits (89), Expect = 0.10
 Identities = 40/148 (27%), Positives = 53/148 (35%), Gaps = 18/148 (12%)

Query: 1831 PGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLT 1890
            P P  +P   P +       S + PG  KP     Q G    G      P +P G     
Sbjct: 153  PPPPGKPQGPPPQGDNKSRSSRSPPG--KPQGPPPQGGNQPQGPPPP--PGKPQGPPPQG 208

Query: 1891 GMRPESQLACCDMVYKLPFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPF-YGPRDPEP 1949
            G +P+            P      G   P P    KS +  +PPG+   P   G   P+ 
Sbjct: 209  GNKPQGP----------PPPGKPQG---PPPQGDNKSQSARSPPGKPQGPPPQGGNQPQG 255

Query: 1950 PEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            P PP  + QG    G ++ Q P P G P
Sbjct: 256  PPPPPGKPQGPPPQGGNKPQGPPPPGKP 283



 Score = 38.5 bits (88), Expect = 0.13
 Identities = 21/60 (35%), Positives = 28/60 (46%), Gaps = 1/60 (1%)

Query: 1919 PAPSVPEKSMADAAPPGQSSSPF-YGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            P P    KS +  +PPG+   P   G   P+ P PP  + QG    G ++ Q P P G P
Sbjct: 286  PPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 345



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 60/243 (24%), Positives = 70/243 (28%), Gaps = 55/243 (22%)

Query: 1391 AGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAR 1450
            AG P+G    A P G  +   P S        P     G+Q +  P  P           
Sbjct: 33   AGNPQG----APPQGGNKPQGPPSPPGKPQGPPPQG--GNQPQGPPPPPG---------- 76

Query: 1451 EKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSP------SESPTFSPGK-MGPRATAE 1503
             KP       G  PQ            PP  P  P      S SP   PGK  GP     
Sbjct: 77   -KPQGPPPQGGNKPQ---------GPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGG 126

Query: 1504 FSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLAS 1563
               Q P P P     +  G P       QG   P +P  P                    
Sbjct: 127  NQPQGPPPPPG----KPQGPPPQGGNKPQGPPPPGKPQGPP---------------PQGD 167

Query: 1564 DASSQTRMVHASASTSPLCSPTETQ--PTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSA 1621
            + S  +R         P     + Q  P   G  Q  PP     P  PP PPG P+ P  
Sbjct: 168  NKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP-PPGKPQGPPP 226

Query: 1622 GAD 1624
              D
Sbjct: 227  QGD 229



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 23/71 (32%), Positives = 31/71 (43%), Gaps = 1/71 (1%)

Query: 1908 PFGSSCTGTFHPAPSVPEKSMADAAPPGQSSSPF-YGPRDPEPPEPPTYRAQGVVGPGPH 1966
            P G    G     P   +KS +  +PPG+   P   G   P+ P PP  + QG    G +
Sbjct: 89   PQGPPPPGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGN 148

Query: 1967 EEQRPYPQGLP 1977
            + Q P P G P
Sbjct: 149  KPQGPPPPGKP 159



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 60/243 (24%), Positives = 70/243 (28%), Gaps = 36/243 (14%)

Query: 3042 PATPSGPT--AFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPGPSTYPAPAFPPGAS 3099
            P  P GP      QP+  PP P       GP   G    Q P  PG    P P      S
Sbjct: 54   PGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDKSRS 110

Query: 3100 YPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVPT 3159
              + PG P  Q   P G    Q P P       P P     P   P          +   
Sbjct: 111  PRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDN 168

Query: 3160 NYEVIASPVVPMSSAPSE--TSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPTYPSD 3217
                  SP       P +      GP    G  QG  P+       G+  Q P P     
Sbjct: 169  KSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ------GGNKPQGPPP----- 217

Query: 3218 SHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSG--RPGKEPGEPGVL 3275
                   Q  P              D+ S +  S   +P GP   G  +P   P  PG  
Sbjct: 218  ---PGKPQGPPPQ-----------GDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263

Query: 3276 DGP 3278
             GP
Sbjct: 264  QGP 266



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 19/58 (32%), Positives = 25/58 (43%), Gaps = 1/58 (1%)

Query: 1921 PSVPEKSMADAAPPGQSSSPF-YGPRDPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            P    K     +PPG+   P   G   P+ P PP  + QG    G ++ Q P P G P
Sbjct: 41   PQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP 98



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 43/183 (23%), Positives = 60/183 (32%), Gaps = 23/183 (12%)

Query: 575 LSTKASPLPSKASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPK 634
           +S + SP     +PQ  P +     + P S   K    P +    P+ PP     P  P 
Sbjct: 23  VSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPP 82

Query: 635 VKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQS--------LSDTGYS 686
            + G +   P  P     P+ P           P   D SRSP+S            G  
Sbjct: 83  PQGGNKPQGPPPP---GKPQGP-----------PPQGDKSRSPRSPPGKPQGPPPQGGNQ 128

Query: 687 SDGISSSQSEITGVVQQEVEQLDSAGVTG-PHPPSPSEIHKVGSSMRPLLQAQGLAPSER 745
             G      +  G   Q   +       G P  P P   +K  SS  P  + QG  P   
Sbjct: 129 PQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGG 188

Query: 746 SKP 748
           ++P
Sbjct: 189 NQP 191



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 50/197 (25%), Positives = 63/197 (31%), Gaps = 18/197 (9%)

Query: 3028 PAGQFVDFPATAAAPATPSGP-----TAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQA-P 3081
            P  Q  + P     P  P GP        Q  R  P  PQ     GG    G P     P
Sbjct: 204  PPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKP 263

Query: 3082 TYPGPSTYPAPAFPPGASYPAEP----GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPAD 3137
              P P     P  PP    P  P    G  ++ +  P G   G  P    Q    P P  
Sbjct: 264  QGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPG 323

Query: 3138 SRAPLQKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSG--YEQGKVP 3195
               P   P Q    +  Q  P   +    P  P   + S ++ S P    G   ++G  P
Sbjct: 324  K--PQGPPPQG--GNKPQGPPPPGKPQGPP--PQGGSKSRSARSPPGKPQGPPQQEGNNP 377

Query: 3196 EVPRAGDRGSVSQSPAP 3212
            + P     G+  Q  AP
Sbjct: 378  QGPPPPAGGNPQQPQAP 394



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 45/176 (25%), Positives = 52/176 (29%), Gaps = 16/176 (9%)

Query: 3042 PATPSG--PTAFQQPRFQPPAPQYSAGSGGPTQNGFPAHQAPTYPG-PSTYPAPAFPPGA 3098
            P  P G  P    QP+  PP P       GP   G    Q P  PG P   P        
Sbjct: 115  PGKPQGPPPQGGNQPQGPPPPP---GKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSR 171

Query: 3099 SYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKPRQTSLADLEQKVP 3158
            S  + PG P  Q   P G    Q P P       P P     P   P          +  
Sbjct: 172  SSRSPPGKP--QGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 229

Query: 3159 TNYEVIASPVVPMSSAPSE--TSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAP 3212
               +   SP       P +      GP    G  QG  P+       G+  Q P P
Sbjct: 230  NKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQ------GGNKPQGPPP 279


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 75.9 bits (185), Expect = 8e-13
 Identities = 143/701 (20%), Positives = 233/701 (33%), Gaps = 56/701 (7%)

Query: 524  SLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPL--PAKASPLSTKASP 581
            SL       P  S  P   A  R S  SP   K  +       P   P+  S + +KA  
Sbjct: 31   SLKSTKSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAPSNRPSSRSRVRSKART 90

Query: 582  LPSKASPQAKPLRASEPSKTPSSVQE---KKTRVP-TKAEPMPKPPPETTPTPATPKVKS 637
             PS+ S   +  +AS+ S      +     + R P  +     K  P    TP   +   
Sbjct: 91   -PSRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHG 149

Query: 638  GVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRS---PQSLSDTGYSSDGISS-S 693
                A P        P + + G      G+P + +  RS   P++LS   Y   G S   
Sbjct: 150  ----ARPGMASRVRTPTSQQKGSRGKSYGRPRTSNRERSDSQPRNLSKKSYRPPGGSGIG 205

Query: 694  QSEITGVVQQEVEQLDSAGVTGPHP---PSPSEIHKVGSSMRPLLQAQ--GLAPSERSKP 748
            +S    V     +     G+        PSPS   KV S  + ++ ++    +P+E S  
Sbjct: 206  RSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSR 265

Query: 749  LSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGS 808
            + S      + RP S S +     S    +        S  W+R   +  +         
Sbjct: 266  VKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQ 325

Query: 809  QLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRG 868
              RH      S+G  S    + P R       ++ R           N  ++ + +  R 
Sbjct: 326  MGRHSQSRSHSKGK-SQNQSRTPRRGRS---HNWSR-----------NPSKERSHSHSRS 370

Query: 869  LAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGL 928
             +K    +G   PR E  +  +  P ++  H+ +    +       A     S +     
Sbjct: 371  SSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNK-------ARDRSRSRSPYKAR 423

Query: 929  RRFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTP 988
             R ++   N            +  D S  R P    +       +++R    S  P+   
Sbjct: 424  DRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKER 483

Query: 989  SYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELRE 1048
             ++   SP+           S  R+ R   +  + +   RS  P        S       
Sbjct: 484  DHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKER 543

Query: 1049 EEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEE 1108
            +    R   + RE  Q R  S  R  RR +   + +R R +S++           SP ++
Sbjct: 544  DRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSK-ERERRQSRSSSEERDHSRSRSPNKQ 602

Query: 1109 ----LRQAAEMEELH---RSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSL 1161
                  +A+  E+ H   R+   E + S S  S  E+ D   S + +S      PT  S 
Sbjct: 603  SGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKES-DPSQSTVPRSPDWKRSPTRTSS 661

Query: 1162 YSPTETPS-----GSSTTPSSGRPLKSAEEAYEEMMRKAEL 1197
             S   TPS       ST PS G+ L   +   +    KA L
Sbjct: 662  LSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQADATTSKATL 702



 Score = 56.2 bits (134), Expect = 6e-07
 Identities = 142/720 (19%), Positives = 233/720 (32%), Gaps = 101/720 (14%)

Query: 3171 MSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSP----APTYPSDSHYTSLEQN 3226
            MSS    +  S     SG         P A  + + S +P     PT P+ S        
Sbjct: 1    MSSPKRSSKPSMSLAPSGSSMPTADPKPPASLKSTKSATPNRSLVPTKPATS-------- 52

Query: 3227 VPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYAR 3286
              RN VM    S+ TK +++    S R     P S  R   +   P  +   T     ++
Sbjct: 53   --RNSVMSPSSSKSTKSTSTKRAPSNR-----PSSRSRVRSKARTPSRVSTDTRT---SK 102

Query: 3287 GEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSK 3346
              + S+   +  RG                TH  G +  R G+R  K        + PS+
Sbjct: 103  ASKASDVRCHQRRG----------------THSRGRTPGRRGSRSSK--------RSPSR 138

Query: 3347 SLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQD 3406
            +  P  I   R+   + GM  ++   +P  + K       SY  P  S+      R+  D
Sbjct: 139  ASTPGRI---RTHGARPGMASRVR--TPTSQQKGSRGK--SYGRPRTSN------RERSD 185

Query: 3407 EITYGLKKNVYEQQ--KYYGMSSRDAVEDDRI-------YGGSSRSRAPSAYSGEKLSSH 3457
                 L K  Y        G SS  AV                 +S  PS  S  K+ S+
Sbjct: 186  SQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSY 245

Query: 3458 D---FSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPL--- 3511
                     K Y     +            S   +HS+ R P RS++  ++   S +   
Sbjct: 246  GQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSH 305

Query: 3512 --------GRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDD 3563
                     R R   G L   G        S      Q       R+H + R        
Sbjct: 306  SWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSH 365

Query: 3564 SHCVVSDSEAYHLGQEET-DWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDE 3622
            SH   S  E  H G         + +    ++ R H      + ++ R  +R  Y   D 
Sbjct: 366  SHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDR 425

Query: 3623 PPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPH 3682
                   P+      R  S  + R     R   +          A+ H+R    ++AR  
Sbjct: 426  SRSRS--PNKARDCSRSRSPYKARDRSRSRSPNK----------ARDHSRSRSPNKARDR 473

Query: 3683 SQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQ 3742
            S+  S        Q G PS     + SR+ S       S+  S++     +   SK   +
Sbjct: 474  SRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQR 533

Query: 3743 AQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQ 3802
             Q +   ++      QS+SPS  +      SR P  ++ ++       ++   Q+R   +
Sbjct: 534  RQSRSPNKER--DRSQSRSPSEER--EHRQSRSPSKERDRRRWRSPSKERERRQSRSSSE 589

Query: 3803 SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA--PQQGRAPQA 3860
             +  +R  +P       +P+         +   P +    + S+ ++K   P Q   P++
Sbjct: 590  ERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRTPSKEGNHSQSRTSSKESDPSQSTVPRS 649



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 105/517 (20%), Positives = 177/517 (34%), Gaps = 59/517 (11%)

Query: 985  ASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQR-KARHRSHGPLLPTIEDSSEE 1043
            A TPS     +PT + S E+  + SPS  ++++   Q    +R +S+ P     E SS  
Sbjct: 211  AVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVKSYGQMIIPSREKSYSPT----EMSSRV 266

Query: 1044 EELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRR---RERSKTPPSNLSPI 1100
            +   +     R Q   +    +R RS ++K    +    + +R   R RS+T    LS +
Sbjct: 267  KSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVRSHSWKRNHSRARSRTRKGILSQM 326

Query: 1101 EDASPTEELRQAAEMEELH-----------RSSCSEYSPSPSLDSEAEALDGGPSRLYKS 1149
               S +    +     +             R+   E S S S  S  E    G S   K 
Sbjct: 327  GRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSKERDHRGSSSPRKE 386

Query: 1150 G--SEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQ-AA 1206
               S+   P     +S + +P+ +     S  P K+ + +      KA    R +    A
Sbjct: 387  SGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKA 446

Query: 1207 GARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQS 1266
              R     P++        S        R+  ++  P+ E   + LG+   E   + S+S
Sbjct: 447  RDRSRSRSPNKARDH----SRSRSPNKARDRSRSRSPSKERDHSQLGSPSKERDHRRSRS 502

Query: 1267 IVRMRQ-------ASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAA 1319
              + RQ       +  RD   +    KE+Q   + S   +  +      +      Q  +
Sbjct: 503  PSKERQCRQSRSSSKERDHRRSRSPSKERQRRQSRSPNKERDRSQSRSPSEEREHRQSRS 562

Query: 1320 PVSF-----------------STPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPAS 1362
            P                    S  +S +    R     + + +         K HS   +
Sbjct: 563  PSKERDRRRWRSPSKERERRQSRSSSEERDHSRSRSPNKQSGYSRPRASSKEKAHSRSRT 622

Query: 1363 PSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHS 1422
            PS          S     P+ + V   P    +   T  S     R+PS +S+     HS
Sbjct: 623  PSKEGNHSQSRTSSKESDPSQSTVPRSPDW--KRSPTRTSSLSQNRTPSKTSS-----HS 675

Query: 1423 PTTANYGSQT--EDLPQAPSGLAAAGRAAREKPLSAS 1457
            P+T   G QT  +D  QA +  + A         S+S
Sbjct: 676  PSTFPSGGQTLSQDDSQADATTSKATLPGERSSSSSS 712



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 74/298 (24%), Positives = 108/298 (36%), Gaps = 42/298 (14%)

Query: 1238 GQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAY 1297
            G +   A    PASL +    +    ++S+V  + A+SR+   +    K  +  + + A 
Sbjct: 18   GSSMPTADPKPPASLKST---KSATPNRSLVPTKPATSRNSVMSPSSSKSTKSTSTKRAP 74

Query: 1298 MDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLH 1357
             +         +   +P++    VS  T TS  S    V    R   H    T       
Sbjct: 75   SNRPSSRSRVRSKARTPSR----VSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSR 130

Query: 1358 SSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAH 1417
            SS  SPS AS          PG   T    P   G+     TP S     R  S      
Sbjct: 131  SSKRSPSRAST---------PGRIRTHGARP---GMASRVRTPTSQQKGSRGKS------ 172

Query: 1418 SYGHSPTTANY---GSQTEDLPQA---PSGLAAAGRAAREKPLSASDGEGGTPQ--PSRA 1469
             YG  P T+N     SQ  +L +    P G +  GR++ E  ++ S  +  TP   PS+ 
Sbjct: 173  -YGR-PRTSNRERSDSQPRNLSKKSYRPPGGSGIGRSS-ELAVTPSTAKCQTPTGIPSKE 229

Query: 1470 YSYFASSSPPLSPSS------PSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSP 1521
             S   S S      S      PS   ++SP +M  R  +     T S   +    RSP
Sbjct: 230  KSDNPSPSSSRKVKSYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSP 287



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 45/210 (21%), Positives = 72/210 (34%), Gaps = 21/210 (10%)

Query: 143 SVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNF--NTCTQCHNKVCNQ 200
           S +P+R   PT P +       PSS+     K++  TST   P+   ++ ++  +K    
Sbjct: 37  SATPNRSLVPTKPATSRNSVMSPSSS-----KSTKSTSTKRAPSNRPSSRSRVRSKARTP 91

Query: 201 CGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGK 260
              + +   ++  +   + C  +R       T  R  S+    SP+ +      +    +
Sbjct: 92  SRVSTDTRTSKASKASDVRCHQRRGTHSRGRTPGRRGSRSSKRSPSRASTPGRIRTHGAR 151

Query: 261 PDQ-ERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRP 319
           P    R R P   Q GSR     R             P          QP   S    RP
Sbjct: 152 PGMASRVRTPTSQQKGSRGKSYGR-------------PRTSNRERSDSQPRNLSKKSYRP 198

Query: 320 PAGEAPAKSATAVPAGLGATEQTQEGLTGK 349
           P G    +S+        A  QT  G+  K
Sbjct: 199 PGGSGIGRSSELAVTPSTAKCQTPTGIPSK 228


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 75.5 bits (184), Expect = 1e-12
 Identities = 168/705 (23%), Positives = 211/705 (29%), Gaps = 92/705 (13%)

Query: 9   GGAGDGPLPPGGAGPGPGPGPGPGAGKPPSAPAGG----GQLPAAGAARSTAVPPVPGPG 64
           G  G  PL     G G       GA  P SAP  G     + PA+G  R    PP     
Sbjct: 51  GAVGRKPLAERAGGIG-------GATIPESAPRAGPTRTSRPPASG--RGERAPPAKNTS 101

Query: 65  PGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASAT-------------------TPG 105
           PGP   PG  S + R  P    G + +A  T  +  AT                   TPG
Sbjct: 102 PGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPG 161

Query: 106 HESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLP 165
             SP   R    AG E   PR       R    G   SVS     + T P    +  P  
Sbjct: 162 TPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA 221

Query: 166 SSTL-CPICKTSDLTSTP-SQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQ 223
              L  P  ++   ++TP S P  +  +             P P   Q            
Sbjct: 222 GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQ------------ 269

Query: 224 RALGMDMTTAPRSKSQQQL----HSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQA 279
            AL     T PR  +   L     SP  +P+ S    P   P  +    P    P     
Sbjct: 270 -ALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATT 328

Query: 280 ETARATSVPGPAQAAAPPEVGRVSPQPPQP----TKPSTAEPRPPAGEAPAKSATAVPAG 335
                T     +   +PP     +P P  P      P  A P PPA    +  AT  P  
Sbjct: 329 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQ- 387

Query: 336 LGATEQTQEGLTGKLFGLGASLLTQA----STLMSVQPEADTQGQPAPSKGTPKIVFNDA 391
             A       L    F    S   QA         V P A    Q  PS   P +    +
Sbjct: 388 --APNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445

Query: 392 SKEAGP-KPLGSGPGPGPAPGAKTEPGARMGPGSGPGAL--PKTGGTTSPK---HGRAEH 445
              + P  P  + P   P P A         P   P AL  P      SP     G+A  
Sbjct: 446 PPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 505

Query: 446 QAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLV 505
             ++     P   P  +A   L    L V    PA+       R          PTP   
Sbjct: 506 SPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRR---------PPTPGPD 556

Query: 506 EKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQ-----KGPQG 560
                  L   T  L  G    P+  P  T   P + A H +S TS  ++      GP+G
Sbjct: 557 TSVSGPRL---TLALAPGPPPPPSRSPSSTLSGPDL-AGHSSSATSTPEELRGYDSGPEG 612

Query: 561 LGQPSGPLP----AKASPLSTKASPLPSKASPQAKPLRASEPSKT-PSSVQEKKTRVPTK 615
            G  + P P    A   P +    P P  A   A       P  T P S     T   T+
Sbjct: 613 -GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETE 671

Query: 616 AEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE 660
                 P P       +P    G   A          P+  + GE
Sbjct: 672 GPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 716



 Score = 70.9 bits (172), Expect = 2e-11
 Identities = 141/597 (23%), Positives = 204/597 (34%), Gaps = 121/597 (20%)

Query: 260 KPDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRP 319
           KP  ER+ G GG       A    +    GP + + PP  GR    PP   K ++  P  
Sbjct: 56  KPLAERAGGIGG-------ATIPESAPRAGPTRTSRPPASGRGERAPP--AKNTSPGPVS 106

Query: 320 PAGEAPAKSATAVPAGLGATEQTQEGL---TGKLFGLGASLLTQASTLMSVQPEADTQGQ 376
             G A   S T  P  LG     Q+GL     +    G +      + +S     DT G 
Sbjct: 107 SPGRA---SGTTRPGPLG-----QKGLRISAEETVARGKATEAPKRSALSAGARRDTSG- 157

Query: 377 PAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGG-- 434
             P+ GTP       S+ AG + +G    P PAP A+  P     P  GP     +    
Sbjct: 158 --PTPGTPSPAMARRSRAAGTE-VGL---PRPAPSARPRP-----PTEGPRKSVSSASEH 206

Query: 435 -TTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGS-----KSPANYNTCTTC 488
            TT P        +A     +P +     +  PL     +  S     ++PA+ +     
Sbjct: 207 STTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPK 266

Query: 489 RLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQ---QPPVGAPH 545
            LQ   L     TP   +    L     +          P+P  PP+ Q    PP   P 
Sbjct: 267 GLQA--LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPS 324

Query: 546 RASGT------------------SPLKQKGPQG---LGQP---SGPLPAKASPLSTKASP 581
           +A+ +                  SPL    PQ    L  P   + P P  + PLS  A+P
Sbjct: 325 QATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATP 384

Query: 582 LPS----------------------------KASPQAKPLRASEPSKTPSSVQEKKTRVP 613
            P                              ASP   P  A+ PS+ P S+     +VP
Sbjct: 385 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSP-SATPPSQAPPSLAAPPLQVP 443

Query: 614 TKAEPMPKPPPETTPTPATPKVKSG--VRRAEP--------ATPVVKAVPEAPKGGEAED 663
                 P   P  TP P  P   +   ++ A+P        ATP ++A+P  P     + 
Sbjct: 444 PSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQ- 502

Query: 664 LVGKPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGP-HPPSPS 722
               P+S  AS     L+     +  + ++      ++Q       S  +  P  PP+P 
Sbjct: 503 ---APFSPSASLPMSPLATPPPQAPPVLAAP-----LLQVPPSPPASPTLQAPRRPPTPG 554

Query: 723 EIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPE---AFDSDEE 776
               V      L  A G  P     P S+ +G +      S + TPE    +DS  E
Sbjct: 555 PDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611



 Score = 69.7 bits (169), Expect = 5e-11
 Identities = 152/690 (22%), Positives = 221/690 (32%), Gaps = 144/690 (20%)

Query: 15  PLPPGGAGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPG 74
           P PPG   P P P   P A +   A    G+ P A  A       +P   P  GP     
Sbjct: 27  PRPPGS--PRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSR 84

Query: 75  STSRRLDPKEPLGNQRAASP--TPKQASATT-PG-------HESPRETRAQGPAGQEADG 124
             +     + P     +  P  +P +AS TT PG         S  ET A+G A    + 
Sbjct: 85  PPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKA---TEA 141

Query: 125 PRRT-LQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPS 183
           P+R+ L   +R   SG +P       +  +         P P+ +  P   T     + S
Sbjct: 142 PKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVS 201

Query: 184 QPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLH 243
             + ++ T+            P+P               +R         P S+S     
Sbjct: 202 SASEHSTTE------------PSP------------AARRRPSAGGGLQRPASRSLSSSA 237

Query: 244 SPALSPAHSPAKQPLGKPDQERSRGPGGP-QPGSRQAETARATSVPGPAQAAAP------ 296
           +P  SPA S      G   +   R P  P QP  +  +  R   V  P + AAP      
Sbjct: 238 TPLSSPARS------GPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291

Query: 297 -PEVGRVSPQ-PPQPTKPSTAE--PRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFG 352
              +   SP  PP P+ P + +  P PPA   P+++ T++  G    + T   L      
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTLPSPPA-TPPSQATTSL--GSPTLQATHSFLPSPPLS 348

Query: 353 LGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGP-GPGPAPG 411
             A+   QA   +++ P       PA    +P    +  +  A    L   P  P P+P 
Sbjct: 349 PLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPP 408

Query: 412 AKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAE 471
            +        P S P + P +   T P       QA    AA P  +P      P     
Sbjct: 409 VQ-------APFSPPASPPVSPSATPPS------QAPPSLAAPPLQVPPSPPASPPMSPS 455

Query: 472 LNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPL 531
                ++P                      P L                    L +P P 
Sbjct: 456 ATPPPQAPPPL-----------------AAPPL-------------------QLAKPPPQ 479

Query: 532 PPPTSQQPPVGA----PHRASGTSPLKQKGPQGLGQPSGPLPAKASPLSTKASPLPSKAS 587
            PP    PP+ A    P    G +P                P+ + P+S  A+P P    
Sbjct: 480 APPALATPPLQALPSPPASFPGQAPFS--------------PSASLPMSPLATPPPQAPP 525

Query: 588 PQAKPLRASEPSKTPSSVQEKKTRVPTKA--------------EPMPKPPPETTP--TPA 631
             A PL    PS   S   +   R PT                 P P PPP  +P  T +
Sbjct: 526 VLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLS 585

Query: 632 TPKVKSGVRRAEPATPVVKAVPEAPKGGEA 661
            P +      A      ++     P+GG A
Sbjct: 586 GPDLAGHSSSATSTPEELRGYDSGPEGGAA 615



 Score = 69.7 bits (169), Expect = 5e-11
 Identities = 156/665 (23%), Positives = 217/665 (32%), Gaps = 116/665 (17%)

Query: 1068 RSTARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEE--------LRQAAEMEELH 1119
            R+   +T R     R +R      T P  +S    AS T          LR +AE E + 
Sbjct: 76   RAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAE-ETVA 134

Query: 1120 RSSCSEYSPSPSLDSEAEALDGGPS----------RLYKSGSEYNLPTFMSLYSPTETPS 1169
            R   +E     +L + A     GP+          R   +G+E  LP           PS
Sbjct: 135  RGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPR--------PAPS 186

Query: 1170 GSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEY 1229
                 P+ G P KS   A E           +   AA  R   GG  Q    R L S   
Sbjct: 187  ARPRPPTEG-PRKSVSSASEHSTT-------EPSPAARRRPSAGGGLQRPASRSLSS--- 235

Query: 1230 QDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQ 1289
               T       + P+A GTP +            SQ   +  QA  R       +K    
Sbjct: 236  -SATPLSSPARSGPSARGTPRAPA--------HPSQPKPKGLQAL-RPPQVTPPRKDAAP 285

Query: 1290 FLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRVIPDVRVTQHFAKE 1349
             L   S+          P +P   P+    P   +TP S  ++     P ++ T  F   
Sbjct: 286  ALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTS-LGSPTLQATHSFLPS 344

Query: 1350 TQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPAGSER- 1408
               PL   ++P  P  A   + +P  Q P +P        PA  P   +   SP      
Sbjct: 345  P--PLSPLATP--PPQAPPALALPPLQAPPSP--------PASPPLSPLATPSPQAPNAL 392

Query: 1409 ---------SPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDG 1459
                     SP PS    +    P +           QAP  LAA        P ++   
Sbjct: 393  AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPM 452

Query: 1460 EGGTPQPSRAYSYFASSSPPLSPSSPSESPTFS--PGKMGPRATAEFSTQTPSPAPASDM 1517
                  P +A    A+    L+   P   P  +  P +  P   A F  Q P  +P++ +
Sbjct: 453  SPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF-SPSASL 511

Query: 1518 PRSP------------GAPT----PSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITL 1561
            P SP             AP     PSP  +   Q P RP TP     ++S   P + + L
Sbjct: 512  PMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP---GPDTSVSGPRLTLAL 568

Query: 1562 ASDASSQTRMVHASASTSP-----LCSPTETQPTTHGY-SQTTPPSVSQLPPEPPGPPGF 1615
            A           +S  + P       S T T     GY S     + +  PP+       
Sbjct: 569  APGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628

Query: 1616 PRVPSAGADGPLALYG-------W--GALPAENISLCRI-------SSVPGTSRVEPGPR 1659
            P   S G   PLA  G       W     P     LC I       S+ P    ++PGP 
Sbjct: 629  PAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGP- 687

Query: 1660 TPGTA 1664
            +PGT+
Sbjct: 688  SPGTS 692



 Score = 67.0 bits (162), Expect = 3e-10
 Identities = 118/522 (22%), Positives = 178/522 (34%), Gaps = 96/522 (18%)

Query: 1164 PTETPSGSSTTPSSGRPL--KSAEEAYEEMMRKAELLQ--RQQGQAAGARGPHGGPSQPT 1219
            P  +P  +S T   G PL  K    + EE + + +  +  ++   +AGAR    GP+  T
Sbjct: 104  PVSSPGRASGTTRPG-PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGT 162

Query: 1220 GPRGLGSFEYQDTTDREYGQAA-----QPAAEGTPASLGAAVYEEILQTSQSIVRMRQAS 1274
                +        T+    + A     +P  EG   S+ +A      + S +  R R ++
Sbjct: 163  PSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA-ARRRPSA 221

Query: 1275 SRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGG 1334
               L     +   +   ++ +    P +   GP   GT       P + + P+     G 
Sbjct: 222  GGGL----QRPASRSLSSSATPLSSPARS--GPSARGT-------PRAPAHPSQPKPKGL 268

Query: 1335 RVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLP 1394
            + +   +VT         P +  ++PA    +S  +  P    P  P + +  P    LP
Sbjct: 269  QALRPPQVT---------PPRKDAAPALGPLSSSPLATP---SPSAPPSPSAPPSLQTLP 316

Query: 1395 RGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPL 1454
                TP S A +          HS+  SP  +   +     PQAP  LA         PL
Sbjct: 317  SPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPP---PQAPPALALP-------PL 366

Query: 1455 SASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPA 1514
             A                     PP  P+SP  SP  +P    P A A    Q P   P 
Sbjct: 367  QA---------------------PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405

Query: 1515 SDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVHA 1574
            S   ++P +P  SP V+     P             SQ  P +        ++    V  
Sbjct: 406  SPPVQAPFSPPASPPVSPSATPP-------------SQAPPSL--------AAPPLQVPP 444

Query: 1575 SASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGA 1634
            S   SP  SP+ T P         PP     PP P  PP     P      P A +  G 
Sbjct: 445  SPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP-PQAPPALATPPLQALPSPPASFP-GQ 502

Query: 1635 LPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTP 1676
             P         +S+P +    P P+ P      L   V P+P
Sbjct: 503  AP-----FSPSASLPMSPLATPPPQAPPVLAAPL-LQVPPSP 538



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 76/303 (25%), Positives = 107/303 (35%), Gaps = 58/303 (19%)

Query: 3599 GGHAVSSSSQKRGPARHSYHDYD-----EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRH 3653
            GG  +  S+ + GP R S           PP +   P     PGR +     R G  G+ 
Sbjct: 66   GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTT--RPGPLGQK 123

Query: 3654 SGRHTGEEP---GRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSR 3710
              R + EE    G+    P    L     R  S P+          PG PS A       
Sbjct: 124  GLRISAEETVARGKATEAPKRSALSAGARRDTSGPT----------PGTPSPA------- 166

Query: 3711 ASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQI--- 3767
                             A    AA      P+  P  + R    GP++S S +S      
Sbjct: 167  ----------------MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE 210

Query: 3768 PSGAASRQPQTQQQQQGLGLQPP-----QQALTQARLQQQSQPTTRGSAPAASQPAGKPQ 3822
            PS AA R+P       G GLQ P       + T      +S P+ RG+  A + P+ +P+
Sbjct: 211  PSPAARRRPSA-----GGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPS-QPK 264

Query: 3823 PGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPG 3882
            P    A  P    PPR +        + +P    +P A P+P   P  ++    P  TP 
Sbjct: 265  PKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPS-APPSLQTLPSPPATPP 323

Query: 3883 APA 3885
            + A
Sbjct: 324  SQA 326



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 92/396 (23%), Positives = 140/396 (35%), Gaps = 99/396 (25%)

Query: 280 ETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGAT 339
           + A+A +      A AP   G ++P+PP         PRPP    PA  A  V    GA 
Sbjct: 6   DKAKAGAAARTPAARAP---GLLTPRPP-------GSPRPPPPVTPA--ALRVLGAAGAV 53

Query: 340 EQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKP 399
            +  + L  +  G+G + + ++                AP  G  +            +P
Sbjct: 54  GR--KPLAERAGGIGGATIPES----------------APRAGPTRT----------SRP 85

Query: 400 LGSGPGPGPAPGAKTEPGARMGPGSGPGAL-PKTGGTTSPKHGRAEHQAASKAAAKPKTM 458
             SG G    P   T PG    PG   G   P   G    +    E  A  KA   PK  
Sbjct: 86  PASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPK-- 143

Query: 459 PKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQTK 518
                     ++ L+ G++   +  T  T            P+P +  ++          
Sbjct: 144 ----------RSALSAGARRDTSGPTPGT------------PSPAMARRS---------- 171

Query: 519 RLLEGSLGEPTPLPPPTSQQPPVG--------APHRASGTSPLKQKGPQ---GLGQP-SG 566
           R     +G P P P    + P  G        + H  +  SP  ++ P    GL +P S 
Sbjct: 172 RAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASR 231

Query: 567 PLPAKASPLSTKASPLPS----------KASPQAKPLRASEPSK-TPSSVQEKKTRVPTK 615
            L + A+PLS+ A   PS           + P+ K L+A  P + TP          P  
Sbjct: 232 SLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLS 291

Query: 616 AEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKA 651
           + P+  P P   P+P+ P     +  + PATP  +A
Sbjct: 292 SSPLATPSPSAPPSPSAPPSLQTL-PSPPATPPSQA 326



 Score = 53.9 bits (128), Expect = 3e-06
 Identities = 103/412 (25%), Positives = 133/412 (32%), Gaps = 65/412 (15%)

Query: 23  PGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRLDP 82
           P P P        P S P      P + A  S A PP+  P P P P   P S S    P
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVP-PSP-PASPPMSPSATPPP 460

Query: 83  KEP----LGNQRAASPTPKQASA-TTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQR 137
           + P        + A P P+   A  TP  ++     A  P GQ    P  +L +      
Sbjct: 461 QAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFP-GQAPFSPSASLPM------ 513

Query: 138 SGRSPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKV 197
              SP  +P   + P     + Q+ P P     P   T      P  P  +T        
Sbjct: 514 ---SPLATPPPQAPPVLAAPLLQVPPSP-----PASPTLQAPRRPPTPGPDTSVS----- 560

Query: 198 CNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQP 257
                    P LT              AL       P       L  P L+  HS +   
Sbjct: 561 --------GPRLT-------------LALAPGPPPPPSRSPSSTLSGPDLA-GHSSSATS 598

Query: 258 LGKPDQERSRGPGGPQPGSRQAETARATSVPGP-AQAAAPPEVGRVSPQPPQPTKPSTAE 316
             +  +    GP G    S   +   A   P   ++  APP   R +P  P P  P+T  
Sbjct: 599 TPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATG- 657

Query: 317 PRPPAG-------EAPAKSATAVPAGL--GATEQTQEGLTGKLFGLGASLLTQASTLMSV 367
           P    G       E P +SAT  P  L  G +  T  G      G GAS  +     +  
Sbjct: 658 PGSADGLCTIYETEGP-ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGE 716

Query: 368 QPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGAR 419
            P    Q        +  ++   A   AG    GSG GPG A G     GAR
Sbjct: 717 LPLGALQASVVQHLLSRTLLLAAAEGAAG----GSGGGPGGAEGGGVTGGAR 764



 Score = 47.4 bits (111), Expect = 3e-04
 Identities = 64/239 (26%), Positives = 85/239 (35%), Gaps = 27/239 (11%)

Query: 2121 GPDLVQYQPQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPGNLAQYGPAAGQGTAVRQL 2180
            GP      P  G G  AP +     PG + +P    G   PG L Q G        V + 
Sbjct: 78   GPTRTSRPPASGRGERAPPAK-NTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVARG 136

Query: 2181 LPSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRG---GMYRPYASG------ 2231
              + A  R+A   + +      +   P T  PA   R    G   G+ RP  S       
Sbjct: 137  KATEAPKRSA---LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPT 193

Query: 2232 -----GITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPA 2286
                  +++    S T     A R P    GL R   P+   ++SS  P   P   G  A
Sbjct: 194  EGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR---PASRSLSSSATPLSSPARSGPSA 250

Query: 2287 AAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAP---APLAGQKPPADAAP 2342
                     PS+P+ P G     P   T P   K+AA A  P   +PLA   P A  +P
Sbjct: 251  RGTPRAPAHPSQPK-PKGLQALRPPQVTPPR--KDAAPALGPLSSSPLATPSPSAPPSP 306



 Score = 47.0 bits (110), Expect = 4e-04
 Identities = 61/210 (29%), Positives = 80/210 (38%), Gaps = 30/210 (14%)

Query: 2157 GHPSPGNLAQYGPAAGQGTAVRQLLPSTATVRAADGMIYSTINTPIAATLPITTQPASVL 2216
            G PSP  +A+   AAG    + +  PS       +G   S  +    +T      PA+  
Sbjct: 161  GTPSPA-MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTE--PSPAARR 217

Query: 2217 RPMVRGGMYRPYA-SGGITAVPLTSLTRVPMIA---PRVPLGPT-----GLYRYPAPSRF 2267
            RP   GG+ RP + S   +A PL+S  R    A   PR P  P+     GL     P   
Sbjct: 218  RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVT 277

Query: 2268 PIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPA 2327
            P      PA GP+    P A  +P A  P  P  P         P T P+    + G+P 
Sbjct: 278  PPRKDAAPALGPL-SSSPLATPSPSA--PPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334

Query: 2328 ------------PAPLA---GQKPPADAAP 2342
                         +PLA    Q PPA A P
Sbjct: 335  LQATHSFLPSPPLSPLATPPPQAPPALALP 364



 Score = 44.3 bits (103), Expect = 0.002
 Identities = 77/299 (25%), Positives = 99/299 (33%), Gaps = 32/299 (10%)

Query: 3036 PATAAAPATPSGPTAFQQPRFQ-PPAPQYS------AGSGGPTQNGFPAH--QAPTYPGP 3086
            P +  A   P  P A   P  Q PP+P  S      A       N    H  QAP  P P
Sbjct: 346  PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405

Query: 3087 STYPAPAFPPGASYPAEP-GLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQKP 3145
            S      F P AS P  P   P  QA  P    A    +P +     P+   +  P Q P
Sbjct: 406  SPPVQAPFSPPASPPVSPSATPPSQA--PPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463

Query: 3146 RQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGS 3205
               +   L+   P      A    P+ + PS      P  S     G+ P  P A    S
Sbjct: 464  PPLAAPPLQLAKPPPQAPPALATPPLQALPS------PPASF---PGQAPFSPSASLPMS 514

Query: 3206 VSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEP-----LGPG 3260
               +P P  P       L+  VP +      +    +  T   PD+    P     L PG
Sbjct: 515  PLATPPPQAPPVLAAPLLQ--VPPSPPASPTLQAPRRPPT-PGPDTSVSGPRLTLALAPG 571

Query: 3261 SSGRPGKEPGEPGVLDGPTLPCCYARGEEESEE-DSYDPRGKGGHLRSMESNGRPASTH 3318
                P + P     L GP L    +      EE   YD   +GG   S   +   A+ H
Sbjct: 572  PPPPPSRSPS--STLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACH 628



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 113/457 (24%), Positives = 161/457 (35%), Gaps = 47/457 (10%)

Query: 1920 APSVPEKSMADAAPP-GQSSSPFYGPR-DPEPPEPPTYRAQGVVGPGPHEEQRPYPQGLP 1977
            A +V  K +A+ A   G ++ P   PR  P     P    +G   P P +   P P   P
Sbjct: 50   AGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPPASGRGERAP-PAKNTSPGPVSSP 108

Query: 1978 GRLYSSMSDTNLAEAGLNYHAQRI---GQLFQGPGRDSAMDLSSLKHSY--SLGFADGRY 2032
            GR   +     L + GL   A+     G+  + P R SA+   + + +   + G      
Sbjct: 109  GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKR-SALSAGARRDTSGPTPGTPSPAM 167

Query: 2033 LGQGLQYGSVTDLRHPTDLLAHPLPMRR--YSSVSNIYSDHRYGPRGDAVGFQEASLAQY 2090
              +    G+   L  P    A P P       SVS+  S+H       A   + ++    
Sbjct: 168  ARRSRAAGTEVGLPRPAPS-ARPRPPTEGPRKSVSSA-SEHSTTEPSPAARRRPSAGGGL 225

Query: 2091 SATTAREISRMCAALNSMDQYGGRHGSGGGGPDLVQYQPQHGP-GLSA---PQ------- 2139
                +R +S     L+S  + G    S  G P    +  Q  P GL A   PQ       
Sbjct: 226  QRPASRSLSSSATPLSSPARSGP---SARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKD 282

Query: 2140 ---SLVPLRPGLLGNPTFPEGHPSPG-----NLAQYGPAAGQGTAVRQLLPSTATVRAAD 2191
               +L PL    L  P+ P   PSP            PA     A   L   + T++A  
Sbjct: 283  AAPALGPLSSSPLATPS-PSAPPSPSAPPSLQTLPSPPATPPSQATTSL--GSPTLQATH 339

Query: 2192 GMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASGGITAVPLTSLTRVPMIAPRV 2251
              + S   +P+A T P    PA  L P+       P AS  ++ +   S      +A  +
Sbjct: 340  SFLPSPPLSPLA-TPPPQAPPALALPPLQAPPS--PPASPPLSPLATPSPQAPNALAVHL 396

Query: 2252 ---PLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGAGGPSRPEMPVGAARE 2308
               P  P       AP   P +  V P+  P     P+ A  P    PS P  P  +   
Sbjct: 397  LQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSA 456

Query: 2309 EPLPTTTP---AAIKEAAGAPAPAPLAGQKPPADAAP 2342
             P P   P   A   + A  P  AP A   PP  A P
Sbjct: 457  TPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALP 493



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 109/466 (23%), Positives = 139/466 (29%), Gaps = 102/466 (21%)

Query: 3446 PSAYSGEKLSSHDFSGWGKGYEREREAV----ERLQKAGPKPSSLSMAHSRVRPPMRSQA 3501
            P    G ++S+ +    GK  E  + +      R   +GP P + S A +R     RS+A
Sbjct: 119  PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMAR-----RSRA 173

Query: 3502 SEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYIL 3561
            +  E     L RP P+  P PP                      +GPR       E    
Sbjct: 174  AGTEVG---LPRPAPSARPRPP---------------------TEGPRKSVSSASE---- 205

Query: 3562 DDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYD 3621
               H     S A            +P                SS++    PAR       
Sbjct: 206  ---HSTTEPSPAARRRPSAGGGLQRPASRSLS----------SSATPLSSPARSG----- 247

Query: 3622 EPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARP 3681
                    P   G P   A A   +    G  + R     P R+ A P    LG   + P
Sbjct: 248  --------PSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPA---LGPLSSSP 294

Query: 3682 HSQPS-SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHS----GPAALQ 3736
             + PS SAP  P       PS      P     +    S      +  HS     P +  
Sbjct: 295  LATPSPSAPPSPSAP----PSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350

Query: 3737 SKAEPQAQPQLQ--GRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQAL 3794
            +   PQA P L     QA P P  S   S    PS  A         Q      PP    
Sbjct: 351  ATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS--PPPSPP 408

Query: 3795 TQARLQQQSQPTTRGSAPAASQ---------------PAGKPQPGPSTATGPQPAGPPRA 3839
             QA     + P    SA   SQ               P   P   PS    PQ   P  A
Sbjct: 409  VQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA 468

Query: 3840 EQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPA 3885
                 +K   +AP     P  Q  P P PA       PG  P +P+
Sbjct: 469  PPLQLAKPPPQAPPALATPPLQALPSP-PASF-----PGQAPFSPS 508



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 42/120 (35%), Positives = 50/120 (41%), Gaps = 14/120 (11%)

Query: 2235 AVPLTSLTRVP-MIAPRVPLGPTGLYRYPAPSRFPIASSVPPAEGPVYLGKPAAAKAPGA 2293
            A   T   R P ++ PR P  P      P P   P A  V  A G V   KP A +A G 
Sbjct: 12   AAARTPAARAPGLLTPRPPGSPR-----PPPPVTPAALRVLGAAGAVGR-KPLAERAGGI 65

Query: 2294 GGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSRPG 2353
            GG + PE    A R  P  T+ P A      AP   P     P   ++PG  SG  +RPG
Sbjct: 66   GGATIPE---SAPRAGPTRTSRPPASGRGERAP---PAKNTSPGPVSSPGRASGT-TRPG 118



 Score = 42.4 bits (98), Expect = 0.009
 Identities = 65/272 (23%), Positives = 90/272 (33%), Gaps = 25/272 (9%)

Query: 3630 PHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPS-SA 3688
            P  EG     +SA EH   +    + R      G +  +P +R L    A P S P+ S 
Sbjct: 191  PPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ--RPASRSLSS-SATPLSSPARSG 247

Query: 3689 PAMPKKGQPGYPSSAEYSQPS-----RASSAYHHASDSKKGSRQAHSGPAALQSKA---E 3740
            P+   +G P  P+     +P      R         D+        S P A  S +    
Sbjct: 248  PSA--RGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPS 305

Query: 3741 PQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQ 3800
            P A P LQ   + P    SQ+ +S   P+  A+           L   PPQ     A   
Sbjct: 306  PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 365

Query: 3801 QQSQPTTRGSAPAASQPAGKPQPGPSTATG----PQPAGPPRAEQTNGSKGTAKAPQQGR 3856
             Q+ P+   S P +  P   P P    A        P  PP +           +P    
Sbjct: 366  LQAPPSPPASPPLS--PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP---- 419

Query: 3857 APQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888
             P +  A  P  A     A P   P +P   P
Sbjct: 420  -PVSPSATPPSQAPPSLAAPPLQVPPSPPASP 450



 Score = 41.6 bits (96), Expect = 0.016
 Identities = 49/195 (25%), Positives = 69/195 (35%), Gaps = 28/195 (14%)

Query: 3030 GQFVDFPATAAAPATPSGPTAFQQPRFQP-PAPQYSAGSGGPTQNGFPAHQA-----PTY 3083
            G     P    +P+ P  P+A   P  Q  P+P  +  S   T  G P  QA     P+ 
Sbjct: 288  GPLSSSPLATPSPSAPPSPSA--PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSP 345

Query: 3084 P-GPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPL 3142
            P  P   P P  PP  + P     P+  A  P    A  +P       +  + A    P 
Sbjct: 346  PLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPP 405

Query: 3143 QKPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSET--SYSGPAVSSGYEQGKVPEVPRA 3200
              P Q   +             + PV P ++ PS+   S + P +       +VP  P A
Sbjct: 406  SPPVQAPFS----------PPASPPVSPSATPPSQAPPSLAAPPL-------QVPPSPPA 448

Query: 3201 GDRGSVSQSPAPTYP 3215
                S S +P P  P
Sbjct: 449  SPPMSPSATPPPQAP 463



 Score = 38.1 bits (87), Expect = 0.17
 Identities = 42/129 (32%), Positives = 53/129 (41%), Gaps = 22/129 (17%)

Query: 3769 SGAASRQPQTQQQQQGL------GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQ 3822
            +GAA+R P  +    GL      G   P   +T A L+        G  P A +  G   
Sbjct: 10   AGAAARTPAARAP--GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI-- 65

Query: 3823 PGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGT-- 3880
                 AT P+ A  PRA  T     T++ P  GR  +A PA    P  V +  R  GT  
Sbjct: 66   ---GGATIPESA--PRAGPTR----TSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTR 116

Query: 3881 PGAPAGQPG 3889
            PG P GQ G
Sbjct: 117  PG-PLGQKG 124



 Score = 37.0 bits (84), Expect = 0.39
 Identities = 69/245 (28%), Positives = 83/245 (33%), Gaps = 49/245 (20%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA--LQSK 3738
            P   P +    P +  P  P+S     P   S++    S       QA    AA  LQ  
Sbjct: 477  PPQAPPALATPPLQALPSPPASFPGQAPFSPSASLP-MSPLATPPPQAPPVLAAPLLQVP 535

Query: 3739 AEPQAQPQLQG--RQAAPGPQQSQS--------------PSSRQIPS--------GAASR 3774
              P A P LQ   R   PGP  S S              P SR   S        G +S 
Sbjct: 536  PSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 595

Query: 3775 QPQTQQQ--------QQGLGLQPPQQALTQARLQQQSQPTTRGSAP--AASQPAGKPQPG 3824
               T ++        + G    PP  A   A         +RG AP  A     G P P 
Sbjct: 596  ATSTPEELRGYDSGPEGGAAASPPPDAELAAC---HPAAWSRGPAPPLAFRGAPGAPLPW 652

Query: 3825 PSTATGPQPA-GPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGA 3883
            P  ATGP  A G     +T G +    AP         P P PG +G KA A  G   GA
Sbjct: 653  PP-ATGPGSADGLCTIYETEGPESATPAPGA-----LDPGPSPGTSGGKAAA--GAGAGA 704

Query: 3884 PAGQP 3888
             +  P
Sbjct: 705  SSRSP 709



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 42/152 (27%), Positives = 55/152 (36%), Gaps = 39/152 (25%)

Query: 2244 VPMIAPRVPLGPTGLYRYPAPSRFPIASSVPPAE----GPVYL-GKPAAAKAPGAGG--- 2295
            +P  APR   GPT   R PA  R       PPA+    GPV   G+ +    PG  G   
Sbjct: 70   IPESAPRA--GPTRTSRPPASGR---GERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG 124

Query: 2296 -----------------PSRPEMPVGAAREEPLPTT---TPAAIKEA------AGAPAPA 2329
                             P R  +  GA R+   PT    +PA  + +       G P PA
Sbjct: 125  LRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPA 184

Query: 2330 PLAGQKPPADAAPGGGSGALSRPGFEKEEASQ 2361
            P A  +PP +      S A      E   A++
Sbjct: 185  PSARPRPPTEGPRKSVSSASEHSTTEPSPAAR 216



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 68/255 (26%), Positives = 88/255 (34%), Gaps = 40/255 (15%)

Query: 2129 PQHGPGLSAPQSLVPLRPGLLGNPTFPEGHPSPG-NLAQYGP----AAGQGTAVRQLLPS 2183
            PQ  P L+AP   VP  P        P   P+PG + +  GP    A   G         
Sbjct: 521  PQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSP 580

Query: 2184 TATVRAAD--GMIYSTINTP-------------IAATLPITTQPASVLRPMVRGGMYRPY 2228
            ++T+   D  G   S  +TP              AA+ P   + A+        G   P 
Sbjct: 581  SSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPL 640

Query: 2229 ASGGITAVPLTSLTRVPMIAPRVPLGPTGLYRYPAP-SRFPIASSVPPAEGPVYLGKPAA 2287
            A  G    P   L   P   P    G   +Y    P S  P   ++ P   P   G  AA
Sbjct: 641  AFRGAPGAP---LPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAA 697

Query: 2288 AKAPGAGGPSRP-------EMPVGAAREEPLP-----TTTPAAIKEAAGAPAPAPLAGQK 2335
            A A GAG  SR        E+P+GA +   +      T   AA + AAG     P   + 
Sbjct: 698  AGA-GAGASSRSPKQARLGELPLGALQASVVQHLLSRTLLLAAAEGAAGGSGGGPGGAE- 755

Query: 2336 PPADAAPGGGSGALS 2350
                   GG   ALS
Sbjct: 756  --GGGVTGGARAALS 768



 Score = 33.9 bits (76), Expect = 3.3
 Identities = 61/234 (26%), Positives = 82/234 (35%), Gaps = 23/234 (9%)

Query: 2129 PQHGPGLSAPQSL--VPLRPGL--------LGNPTFPEGH---PSP--GNLAQYGPAAGQ 2173
            P   P  SAP SL  +P  P          LG+PT    H   PSP    LA   P A  
Sbjct: 300  PSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP 359

Query: 2174 GTAVRQLL--PSTATVRAADGMIYSTINTPIAATLPITTQPASVLRPMVRGGMYRPYASG 2231
              A+  L   PS         +   +   P A  + +   P S          + P AS 
Sbjct: 360  ALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASP 419

Query: 2232 GITAVPLTSLTRVPMIA-PRVPLGPTGLYRYP-APSRFPIASSVPP-AEGPVYLGKPAAA 2288
             ++          P +A P + + P+     P +PS  P   + PP A  P+ L KP   
Sbjct: 420  PVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQ 479

Query: 2289 KAPGAGGPSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAP 2342
              P    P    +P   A        +P+A    +    P P   Q PP  AAP
Sbjct: 480  APPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPP---QAPPVLAAP 530



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 40/145 (27%), Positives = 47/145 (32%), Gaps = 39/145 (26%)

Query: 17  PPGGAGPGP----------------GPGP------GPGAGKPPSAPAGGGQLPAAGAARS 54
           P GGA   P                GP P       PGA  P     G G          
Sbjct: 610 PEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYE 669

Query: 55  TAVPPVPGPGPGP-GPGPGPGSTSRRLDPKEPLGNQRAASPTPKQA----------SATT 103
           T  P    P PG   PGP PG++  +       G   A+S +PKQA           A+ 
Sbjct: 670 TEGPESATPAPGALDPGPSPGTSGGKAAAGAGAG---ASSRSPKQARLGELPLGALQASV 726

Query: 104 PGHESPRE---TRAQGPAGQEADGP 125
             H   R      A+G AG    GP
Sbjct: 727 VQHLLSRTLLLAAAEGAAGGSGGGP 751


>gi|221139761 zinc finger protein 853 [Homo sapiens]
          Length = 659

 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 46/123 (37%), Positives = 85/123 (69%), Gaps = 9/123 (7%)

Query: 2355 EKEEASQEER--QRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHR--EEEQL 2410
            E++   Q+E+  Q+ Q++QLLQ ++E+++ ++L  L+ QE+L++++ + Q+ +  +++QL
Sbjct: 184  EQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQL--LQQQEQLQQQQFQQQQEQLQQQQQL 241

Query: 2411 LVQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQRLQLEQIQQLQQQLQQQLEEQK 2470
            L+   LQ+   ++  +LQQQQ + Q Q   Q++   QQ+L L+Q +QLQQQ QQQL +Q+
Sbjct: 242  LL---LQQQGQLQQQLLQQQQAQLQQQLLEQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQ 298

Query: 2471 QRQ 2473
            Q Q
Sbjct: 299  QEQ 301



 Score = 71.2 bits (173), Expect = 2e-11
 Identities = 65/222 (29%), Positives = 108/222 (48%), Gaps = 46/222 (20%)

Query: 2284 KPAAAKAPGAGG------PSRPEMPVGAAREEPLPTTTPAAIKEAAGAPAPAPLAGQKPP 2337
            +PA +   GA        P + E+ +    ++P P   P    E    P P     Q+P 
Sbjct: 66   RPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQ--HEQLQQPQPHLELQQQPQ 123

Query: 2338 ADAAPGGGSGALSRPGFEKEEA----------------SQEERQRKQQEQLLQLERERVE 2381
             D     G   LS+   EK ++                 Q + Q+ Q++Q LQ ++E+++
Sbjct: 124  QD-----GQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQ 178

Query: 2382 LEKLRQLRLQEELERERVELQRHREEEQLLVQRELQELQTIKHHVLQQQQEERQAQFALQ 2441
             ++ ++ ++ ++ E    +LQ+  +E+QLL Q   Q+ Q  +  +LQQQ++ +Q QF  Q
Sbjct: 179  TQQAQEQQVLQQQE----QLQQQVQEQQLLQQ---QQEQLQQQQLLQQQEQLQQQQFQQQ 231

Query: 2442 REQLAQQ----------RLQLEQIQQLQQQLQQQLEEQKQRQ 2473
            +EQL QQ          +LQ + +QQ Q QLQQQL EQ+Q Q
Sbjct: 232  QEQLQQQQQLLLLQQQGQLQQQLLQQQQAQLQQQLLEQQQAQ 273



 Score = 70.5 bits (171), Expect = 3e-11
 Identities = 57/185 (30%), Positives = 99/185 (53%), Gaps = 21/185 (11%)

Query: 2296 PSRPEM--PVGAAR--EEPLPTTTPAAIKEAAGAPAPAPLAGQKPPADAAPGGGSGALSR 2351
            P RP +  PVGA+   EE  P      +++    P P     Q+P  +         L +
Sbjct: 64   PQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQ----QQPQHEQ--------LQQ 111

Query: 2352 PGFEKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLL 2411
            P    E   Q++ Q+  Q+QL QL++E+ +    ++L+ + +L  ++ +LQ  + +EQ  
Sbjct: 112  PQPHLE--LQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQLMHQQQQLQPQQVQEQQR 169

Query: 2412 VQRELQELQTIKHHVLQQQQEERQAQFALQREQLAQQ---RLQLEQIQQLQQQLQQQLEE 2468
            +Q++ ++LQT +    Q  Q++ Q Q  +Q +QL QQ   +LQ +Q+ Q Q+QLQQQ  +
Sbjct: 170  LQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQ 229

Query: 2469 QKQRQ 2473
            Q+Q Q
Sbjct: 230  QQQEQ 234



 Score = 66.6 bits (161), Expect = 5e-10
 Identities = 58/186 (31%), Positives = 94/186 (50%), Gaps = 31/186 (16%)

Query: 2361 QEERQRKQQEQLLQLERERVELEKLR-------------------QLRLQEELERERVEL 2401
            QE+ Q++QQ+QLLQ ++E+++ ++L+                    L  ++ELE++R EL
Sbjct: 283  QEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQEL 342

Query: 2402 QRHREEEQLLVQRELQ-----ELQTIKHHVLQQQQ--EERQAQFALQREQLA--QQRLQL 2452
            +R +E E+   QR+LQ     ELQ ++  + QQQQ  E+++ Q  L   +L   QQ +QL
Sbjct: 343  ERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQL 402

Query: 2453 EQIQQLQQQLQQQLEEQKQRQKAPFPAACEAPGRGPPLAAAELAQNGQYWPPLTHAAFIA 2512
            E +  +Q +LQ +L        A  P A  A    PP     + Q     P +   A +A
Sbjct: 403  E-LTPVQPELQLELVPAAGGGGAAVPGAPAAVVVAPP--GYVVVQELMVLPAVAAPAVVA 459

Query: 2513 MAGPEG 2518
            + GP G
Sbjct: 460  IPGPAG 465



 Score = 64.7 bits (156), Expect = 2e-09
 Identities = 39/117 (33%), Positives = 79/117 (67%), Gaps = 6/117 (5%)

Query: 2362 EERQRKQQEQLLQLERERVELEKLRQL--RLQEELERERVELQRHREEEQLLVQRELQEL 2419
            E++Q + Q+QLL  ++E+++ ++ +QL  + QE+L++++++      EE+  V+ EL  +
Sbjct: 268  EQQQAQLQQQLLLQQQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPV 327

Query: 2420 QTIKHHVLQQQQEERQAQFALQREQLAQQRLQL---EQIQQLQQQLQQQLEEQKQRQ 2473
                   L+QQ++E + Q  L+R+Q  Q++LQL   E++QQL+QQL+QQ ++ +Q++
Sbjct: 328  DLGSEQELEQQRQELERQQELERQQ-EQRQLQLKLQEELQQLEQQLEQQQQQLEQQE 383



 Score = 59.7 bits (143), Expect = 6e-08
 Identities = 45/146 (30%), Positives = 84/146 (57%), Gaps = 30/146 (20%)

Query: 2355 EKEEASQEERQRKQQEQLLQLERERVELEKLRQLRLQEELERERVELQRHREEEQLLVQR 2414
            ++++  Q++ Q +QQ+QLL L+++    ++L Q + Q +L+++ +E Q+ + ++QLL+Q+
Sbjct: 224  QQQQFQQQQEQLQQQQQLLLLQQQGQLQQQLLQQQ-QAQLQQQLLEQQQAQLQQQLLLQQ 282

Query: 2415 ELQELQTIKHHVLQQQQEERQAQFALQ-----------------------REQLAQQRLQ 2451
            + Q  Q  +  +LQQQQE+ Q Q  LQ                        ++L QQR +
Sbjct: 283  QEQLQQQQQQQLLQQQQEQLQQQ-QLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQE 341

Query: 2452 LEQIQQL-----QQQLQQQLEEQKQR 2472
            LE+ Q+L     Q+QLQ +L+E+ Q+
Sbjct: 342  LERQQELERQQEQRQLQLKLQEELQQ 367



 Score = 37.4 bits (85), Expect = 0.30
 Identities = 38/135 (28%), Positives = 53/135 (39%), Gaps = 11/135 (8%)

Query: 3675 GRHEARPHSQP---SSAPAMPKKGQP-GYPSSAEYSQPSRASSAYHHASDSKKGSRQA-H 3729
            G  E++   +P   +S+P  P    P G    AE ++P +            +  +Q  H
Sbjct: 47   GGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQH 106

Query: 3730 SGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQP 3789
                  Q   E Q QPQ  G+Q     QQ +  S           +P+ Q   Q   LQ 
Sbjct: 107  EQLQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHH-----QELKPELQLMHQQQQLQ- 160

Query: 3790 PQQALTQARLQQQSQ 3804
            PQQ   Q RLQQQ +
Sbjct: 161  PQQVQEQQRLQQQQE 175



 Score = 36.2 bits (82), Expect = 0.66
 Identities = 27/81 (33%), Positives = 35/81 (43%), Gaps = 9/81 (11%)

Query: 3730 SGPAALQSKAEPQAQPQLQGRQAAPGP------QQSQSPSSRQIPSGAASRQPQTQQQQQ 3783
            SG +  Q + EPQ +     R A   P       +   P  R++      +QP+ QQQ Q
Sbjct: 46   SGGSESQEEEEPQERNSSPQRPAVSAPVGASEIAEETRPGQRELQLQQLEQQPEPQQQPQ 105

Query: 3784 GLGLQPPQQALTQARLQQQSQ 3804
               LQ PQ  L    LQQQ Q
Sbjct: 106  HEQLQQPQPHL---ELQQQPQ 123



 Score = 35.4 bits (80), Expect = 1.1
 Identities = 24/120 (20%), Positives = 62/120 (51%), Gaps = 12/120 (10%)

Query: 1003 EEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDS-----------SEEEELREEEE 1051
            +++      ++Q L++ ++Q + +     PL P  E+            SE+E  ++ +E
Sbjct: 282  QQEQLQQQQQQQLLQQQQEQLQQQQLQPPPLEPEEEEEVELELMPVDLGSEQELEQQRQE 341

Query: 1052 LLREQEKMREVEQQRIR-STARKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELR 1110
            L R+QE  R+ EQ++++     + ++ +++L  Q+++   +     L+P+E  +  +E++
Sbjct: 342  LERQQELERQQEQRQLQLKLQEELQQLEQQLEQQQQQLEQQEVQLELTPVELGAQQQEVQ 401



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 28/148 (18%), Positives = 72/148 (48%), Gaps = 19/148 (12%)

Query: 961  ELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTS-----LSSLEEDSDSSPS---- 1011
            EL+++ L   PE + + +H   L    P       P       LS L+++   S      
Sbjct: 88   ELQLQQLEQQPEPQQQPQHEQ-LQQPQPHLELQQQPQQDGQQQLSQLQQEKHQSVHHQEL 146

Query: 1012 --------RRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVE 1063
                    ++Q+L+  + Q + R +     L T + + E++ L+++E+L ++ ++ + ++
Sbjct: 147  KPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQT-QQAQEQQVLQQQEQLQQQVQEQQLLQ 205

Query: 1064 QQRIRSTARKTRRDKEELRAQRRRERSK 1091
            QQ+ +   ++  + +E+L+ Q+ +++ +
Sbjct: 206  QQQEQLQQQQLLQQQEQLQQQQFQQQQE 233



 Score = 33.5 bits (75), Expect = 4.3
 Identities = 35/140 (25%), Positives = 50/140 (35%), Gaps = 4/140 (2%)

Query: 3668 KPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQ 3727
            +P  R+L   +     +P   P   +  QP  P      QP +           +K    
Sbjct: 83   RPGQRELQLQQLEQQPEPQQQPQHEQLQQP-QPHLELQQQPQQDGQQQLSQLQQEKHQSV 141

Query: 3728 AHSG--PAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQ-QQG 3784
             H    P       + Q QPQ    Q     QQ Q  + +        +Q Q QQQ Q+ 
Sbjct: 142  HHQELKPELQLMHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQ 201

Query: 3785 LGLQPPQQALTQARLQQQSQ 3804
              LQ  Q+ L Q +L QQ +
Sbjct: 202  QLLQQQQEQLQQQQLLQQQE 221



 Score = 33.1 bits (74), Expect = 5.6
 Identities = 45/248 (18%), Positives = 106/248 (42%), Gaps = 41/248 (16%)

Query: 847  ILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYE 906
            +LE+   ED     DT + G G      ++  P+ R    Q PA         +A  G  
Sbjct: 26   VLELQCLEDGGPGPDTLSGGSG-GSESQEEEEPQERNSSPQRPAV--------SAPVGAS 76

Query: 907  ELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLD--REPELE- 963
            E+     + E   G   LQ      + +E         + +  Q P P L+  ++P+ + 
Sbjct: 77   EI-----AEETRPGQRELQ-----LQQLEQQPEPQQQPQHEQLQQPQPHLELQQQPQQDG 126

Query: 964  MESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSR---RQRLEEAK 1020
             + L+   +++ +  H   L               L  + +     P +   +QRL++ +
Sbjct: 127  QQQLSQLQQEKHQSVHHQELKPE------------LQLMHQQQQLQPQQVQEQQRLQQQQ 174

Query: 1021 QQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVE--QQRIRSTARKTRRDK 1078
            +Q + +      +L   +    +++++E++ L ++QE++++ +  QQ+ +   ++ ++ +
Sbjct: 175  EQLQTQQAQEQQVLQ--QQEQLQQQVQEQQLLQQQQEQLQQQQLLQQQEQLQQQQFQQQQ 232

Query: 1079 EELRAQRR 1086
            E+L+ Q++
Sbjct: 233  EQLQQQQQ 240



 Score = 32.7 bits (73), Expect = 7.3
 Identities = 38/143 (26%), Positives = 56/143 (39%), Gaps = 12/143 (8%)

Query: 3668 KPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQ 3727
            +P  +   +HE     QP     +  + QP      + SQ  +      H  + K   + 
Sbjct: 97   QPEPQQQPQHEQLQQPQPH----LELQQQPQQDGQQQLSQLQQEKHQSVHHQELKPELQL 152

Query: 3728 AHSG----PAALQSKAE-PQAQPQLQGRQAAPGPQ-QSQSPSSRQIPSGAASRQPQTQQQ 3781
             H      P  +Q +    Q Q QLQ +QA      Q Q    +Q+      +Q Q Q Q
Sbjct: 153  MHQQQQLQPQQVQEQQRLQQQQEQLQTQQAQEQQVLQQQEQLQQQVQEQQLLQQQQEQLQ 212

Query: 3782 QQGLGLQPPQQALTQARLQQQSQ 3804
            QQ L  Q  Q+ L Q + QQQ +
Sbjct: 213  QQQLLQQ--QEQLQQQQFQQQQE 233



 Score = 32.3 bits (72), Expect = 9.5
 Identities = 25/63 (39%), Positives = 30/63 (47%), Gaps = 7/63 (11%)

Query: 3742 QAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQ 3801
            Q Q QLQ +Q     +Q Q    +Q       +Q Q QQQQQ L LQ   Q   Q   QQ
Sbjct: 206  QQQEQLQQQQLLQQQEQLQQQQFQQ-------QQEQLQQQQQLLLLQQQGQLQQQLLQQQ 258

Query: 3802 QSQ 3804
            Q+Q
Sbjct: 259  QAQ 261


>gi|60097902 filaggrin [Homo sapiens]
          Length = 4061

 Score = 75.1 bits (183), Expect = 1e-12
 Identities = 176/769 (22%), Positives = 256/769 (33%), Gaps = 91/769 (11%)

Query: 3172 SSAPSETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPT---YPSDSHY----TSLE 3224
            S   SE+++   A S+G  QG   E  R   R S SQ    T   +P  S      +  E
Sbjct: 1447 SHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHE 1506

Query: 3225 QNVPRNYVMIDDISELTKDSTSTAPDSQ----------RLEPLGPGSSGRPGKEPGEPGV 3274
            Q+V R+       S  T    S A   Q          R E      S   G    EP  
Sbjct: 1507 QSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPST 1566

Query: 3275 LDGPTLPCCYARGEEESEEDSY-------DPRGKGGHLRSMESNGRPASTHYYGDS--DY 3325
              G +      +GE    + S          R   GH    E     AS ++YG +    
Sbjct: 1567 RAGSSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQS 1626

Query: 3326 RHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDL 3385
            RHG+R       P   +    S   +A SS++S  R           S  E+A+    + 
Sbjct: 1627 RHGSR------NPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGER 1680

Query: 3386 --ASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRS 3443
              + +   A SS+    GR+ QD    G   N          SS     D   +   S +
Sbjct: 1681 HGSRHQQSADSSTDSGTGRR-QDSSVVGDSGN--------RGSSGSQASDSEGHSEESDT 1731

Query: 3444 RAPSAY--SGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPM--RS 3499
            ++ SA+  +G    SH  S  G+  ER   +   L +      S S AH R  P    R 
Sbjct: 1732 QSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSES-AHGRTGPSTGGRQ 1790

Query: 3500 QASEEESPVSPLGRPRPAGGPLPPG--GDTCPQFCSSHSMPDVQEHVKDGPR-AHAYKRE 3556
            ++  E++  S        G     G  G +      SH    V      G   +H   +E
Sbjct: 1791 RSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQE 1850

Query: 3557 EGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSS--------Q 3608
                 D S             + E    D  R + S   RHH   + + SS        Q
Sbjct: 1851 RS---DVSRGQSGSRSVSRQTRNEKQSGDGSRHSGS---RHHEASSRADSSRHSQVGQGQ 1904

Query: 3609 KRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHG---DHGRHSGRHTGEEPGRR 3665
              GP            +     H E       SA  +  G   +  R   RH G     R
Sbjct: 1905 SSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDR 1964

Query: 3666 AAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAE----YSQPSRASSAYHH---- 3717
            A   H+ D  R     H++ SS        +    S+ E    + Q   A S+ H     
Sbjct: 1965 AGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGH 2024

Query: 3718 ---ASDSKKGSRQAHSGPAALQSKAEPQ-AQPQLQGRQAAPGPQQSQSPSSRQIPSGAAS 3773
               +S  +    + +SG  A  S+   + +  Q    Q   GP Q     S +  SG +S
Sbjct: 2025 GQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESS 2084

Query: 3774 -------RQPQTQQQQQGL-GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGP 3825
                    Q  T +Q +   G   P     Q     Q+Q ++R SA    Q   +  PGP
Sbjct: 2085 GRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGP 2144

Query: 3826 STATGPQPAGPPRAEQTNGSKGT--AKAPQQGRAPQAQPAPGPGPAGVK 3872
            S   G Q +   ++   +G  G+  +    QGR+  ++   G   A  K
Sbjct: 2145 SRG-GRQGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRK 2192



 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 144/694 (20%), Positives = 238/694 (34%), Gaps = 92/694 (13%)

Query: 3237 ISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSY 3296
            I +   D+T +  +  ++      S G+   +       +   +P   +R  +       
Sbjct: 239  IQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVS 298

Query: 3297 DPRGKGGHLRSMESNGRPASTHYYGDS--DYRHGARVEKYGPGPMGPKHPSKSLAPAAIS 3354
              R   GH    E +   AS +++G +    R G+R       P        S   +A S
Sbjct: 299  QDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSR------HPRSHDEDRASHGHSADS 352

Query: 3355 SKRSKHRKQGMEQKISKFSPIEEAKDVESDL--ASYPPPAVSSSLVSRGRKFQDEITYGL 3412
            S++S  R      +    S  E+A+    +   + +   A SS   + GR        G 
Sbjct: 353  SRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGR--------GQ 404

Query: 3413 KKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAY--SGEKLSSHDFSGWGKGYERER 3470
              +    + + G S   A  D   +  +S +++ S +  +G +  SH  S  G+  ER  
Sbjct: 405  ASSAVSDRGHRGSSGSQA-SDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGRSGERSG 463

Query: 3471 EAVERLQKAGP--KPSSL------------SMAHSRVRPPMRSQASEEESPVSPLGRPRP 3516
             +   L +     +P S                H + R   R  AS+E       G+   
Sbjct: 464  RSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQE-------GQDTI 516

Query: 3517 AGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHL 3576
             G P    G +      SH    V      G   H++   +G   D SH       A   
Sbjct: 517  RGHP----GSSRGGRQGSHHEQSVNRSGHSGSH-HSHTTSQGRS-DASHGQSGSRSASRQ 570

Query: 3577 GQEETDWFDKPRDARSDRFRHHGGHAVSSSS--------QKRGPARHSYHDYDEPPEEGL 3628
             + E    D  R + S   RHH   + + SS        Q  GP            +   
Sbjct: 571  TRNEEQSGDGTRHSGS---RHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDS 627

Query: 3629 WPHDEGGPGRHASAKEHRHG---DHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQP 3685
              H E       SA  + HG   +  R   RH       RA   H+ D  R     H+Q 
Sbjct: 628  QGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQN 687

Query: 3686 SSAPAMPKKGQPGYPSSAE---------YSQPSRASSAYHHASDS--KKGSRQAHSGPAA 3734
            SS+       +    S+ E          +  SR S   H  + S  +    +  SG  A
Sbjct: 688  SSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQA 747

Query: 3735 LQSK--AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQT--------QQQQQG 3784
              S+  +E      + G   A   QQS   S+R   SG  SR+  +        +Q +  
Sbjct: 748  TDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARD-RSGERSRRSGSFLYQVSTHKQSESS 806

Query: 3785 LGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNG 3844
             G   P   + Q    +Q++  +R SA    Q   +  PG S+  G Q +   ++   +G
Sbjct: 807  HGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPG-SSRRGRQGSHHEQSVDRSG 865

Query: 3845 SKGT--AKAPQQGRAPQAQPAPGPGPAGVKAGAR 3876
              G+  +    QGR+  ++     G +G ++ +R
Sbjct: 866  HSGSHHSHTTSQGRSDASR-----GQSGSRSASR 894



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 162/768 (21%), Positives = 254/768 (33%), Gaps = 104/768 (13%)

Query: 3176 SETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPT---YPSDSHY----TSLEQNVP 3228
            SE+S+     S+G  QG   E  R   R S SQ    T   +P  S      +  EQ+V 
Sbjct: 803  SESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVD 862

Query: 3229 RNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPT-LPCCYARG 3287
            R+       S  T    S A   Q       GS         E    DG       +   
Sbjct: 863  RSGHSGSHHSHTTSQGRSDASRGQ------SGSRSASRTTRNEEQSRDGSRHSGSRHHEA 916

Query: 3288 EEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKS 3347
               ++   +   G+G    S  S  + +S     DS+  H    E++  G     H   +
Sbjct: 917  SSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE-GHSEDSERWS-GSASRNHRGSA 974

Query: 3348 LAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDE 3407
                  S   S+H +   E +       + ++   +  A       ++S   + R    E
Sbjct: 975  QEQ---SRHGSRHPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGE 1031

Query: 3408 ITYGLKKNVYEQQKYYGMSSR---DAVEDDRIYGGSSRSRAPSAYSGEKLSSHDFSGWGK 3464
                  +   +  ++ G+  R    AV D   +G S    + S    E+  +   SG G+
Sbjct: 1032 RHGSRHQQSADSSRHSGIPRRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQ 1091

Query: 3465 G--YEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPAGGPLP 3522
               +++  +   R    G    S S  +         Q S  E   S  GR R + G   
Sbjct: 1092 DGPHQQSHQESARDWSGGRSGRSGSFIY---------QVSTHEQSESAHGRTRTSTGRRQ 1142

Query: 3523 PGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLGQEETD 3582
                   +  S HS     +  +D  RAH   R  G     SH   S   + H G   + 
Sbjct: 1143 GSHHEQARDSSRHS---ASQEGQDTIRAHPGSRRGG--RQGSHHEQSVDRSGHSGSHHSH 1197

Query: 3583 WFDKPRDARS--------------------DRFRHHGG-------------HAVSSSSQK 3609
               + R   S                    D  RH G              H+     Q 
Sbjct: 1198 TTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQS 1257

Query: 3610 RGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHG---DHGRHSGRHTGEEPGRRA 3666
             G     +       +     H +       SA  + HG   +  R   RH G     RA
Sbjct: 1258 SGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFHQEDRA 1317

Query: 3667 AKPHARDLGRHEARPHSQPSS-----APAMPKKGQPG------YPSSAEYSQPS-----R 3710
            +  H+ D  R     H++ SS     +     +  PG      +  SA+ S+ S     +
Sbjct: 1318 SHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGIGHRQ 1377

Query: 3711 ASSA-----YHHASDSKKGSRQAHSGPAALQS-KAEPQAQPQLQG-RQAAPGPQQSQSPS 3763
            ASSA     +  +S S+  + + HS  +  QS  A  QA P  Q  +++A G     S  
Sbjct: 1378 ASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGR 1437

Query: 3764 SRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQP 3823
            SR      +S     +Q +   G   P     Q    +Q++ ++R SA    Q   +  P
Sbjct: 1438 SRSFLYQVSSH----EQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHP 1493

Query: 3824 GPSTATGPQPAGPPRAEQTNGSKG--TAKAPQQGRAPQAQPAPGPGPA 3869
            G S+  G Q +   ++   +G  G   +    QGR+  +    GP  A
Sbjct: 1494 G-SSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSA 1540



 Score = 58.2 bits (139), Expect = 2e-07
 Identities = 130/594 (21%), Positives = 197/594 (33%), Gaps = 96/594 (16%)

Query: 3176 SETSYSGPAVSSGYEQGKVPEVPRAGDRGSVSQSPAPT---YPSD-------SHYTSLEQ 3225
            SE+++     S+G  QG   E  R   R S SQ    T   +P         SHY   EQ
Sbjct: 3396 SESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHY---EQ 3452

Query: 3226 NVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLDGPTLPCCY- 3284
            +V R+       S  T    S A   Q     G  S+ R  +   + G  DG      + 
Sbjct: 3453 SVDRSGHSGSHHSHTTSQGRSDASRGQS----GSRSASRQTRNDEQSG--DGSRHSWSHH 3506

Query: 3285 --ARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPK 3342
              A  + +S   S   +G+    R+  + G   S     DSD +  +   +   G     
Sbjct: 3507 HEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQ----DSDSQGHSEDSERWSGSASRN 3562

Query: 3343 HPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGR 3402
            H   +      S   S+H     E +       E ++   +  A       ++S   + R
Sbjct: 3563 HRGSAQEQ---SRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQAR 3619

Query: 3403 KFQDEITYGLKKNVYEQQKYYGM---SSRDAVEDDRIYGGSSRSRAPSAYSGEKLSSHDF 3459
                E      +   +  ++ G+    +  AV D    G S    + S    E   +   
Sbjct: 3620 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV 3679

Query: 3460 SGWGKG--YEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQASEEESPVSPLGRPRPA 3517
            S  G+   +++  +   R + AG    S S  +         Q S  E   S  GR  P+
Sbjct: 3680 SAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLY---------QVSTHEQSESAHGRAGPS 3730

Query: 3518 GGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEAYHLG 3577
             G          +  S HS     +  +D  R H   R  G              +YH  
Sbjct: 3731 TGGRQGSRHEQARDSSRHS---ASQEGQDTIRGHPGSRRGG-----------RQGSYH-- 3774

Query: 3578 QEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPG 3637
                       +   DR  H G H   ++SQ R  A H          E       G   
Sbjct: 3775 -----------EQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGS 3823

Query: 3638 RHASAKEHR---HGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKK 3694
            RH+ ++ H      D  RHS    GE  G R +        R +    SQ S + A    
Sbjct: 3824 RHSGSRHHEASTQADSSRHSQSGQGESAGSRRS--------RRQGSSVSQDSDSEA---- 3871

Query: 3695 GQPGYPSSAEYSQPSRASSAYHHAS---DSKKGSRQAHSGPAALQSKAEPQAQP 3745
                YP  +E  + S ++S  HH S    S+ GSR  H G +   + +  Q+ P
Sbjct: 3872 ----YPEDSE--RRSESASRNHHGSSREQSRDGSR--HPGSSHRDTASHVQSSP 3917



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 140/650 (21%), Positives = 221/650 (34%), Gaps = 73/650 (11%)

Query: 3304 HLRSMESNGRPASTHYYGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRS--KHR 3361
            H  S++S+G   S H +  S  R  A   +   G       +++   +  SS+ S  +H 
Sbjct: 3126 HEHSVDSSGHSGSHHSHTTSQGRSDA--SRGQSGSRSASRTTRNEEQSGDSSRHSVSRHH 3183

Query: 3362 KQGMEQKISKFSPIEEAKDVESDLASYPPPAVSSSLVSRGRKFQDEITYGL-----KKNV 3416
            +      IS+ S   + +   S  +     +VS    S G     E   G      + +V
Sbjct: 3184 EASTHADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSV 3243

Query: 3417 YEQQKYYGMSSRDAVEDDRIYGGSS-RSR------APSAYSGEKLSSHDFSGWGKGYE-- 3467
             EQ ++     R   ED   +G S+ RSR      A ++  G+  SSH+ +    G    
Sbjct: 3244 QEQSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHG 3303

Query: 3468 -REREAVERLQKAG-PK-PSSLSMAHSRVRPPMRSQASE-----EESPVSPLGRPRPAGG 3519
             R +++ +  + +G P+  +S ++  SR      SQAS+     EES    +     AG 
Sbjct: 3304 SRHQQSADSSRHSGIPRGQASSAVRDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGP 3363

Query: 3520 PLPPGGDTCPQFCSSHS------MPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSDSEA 3573
                  ++        S      +  V  H +        +   G      H    DS  
Sbjct: 3364 HQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSR 3423

Query: 3574 YHLGQEETDWF-DKPRDARS-----------DRFRHHGGHAVSSSSQKRGPARHSYHDYD 3621
            +   QE  D     P  +R            DR  H G H   ++SQ R  A        
Sbjct: 3424 HSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSR 3483

Query: 3622 EPPEEGLWPHDEGGPGRHASAKEHR---HGDHGRHSGRHTGEEPGRRAAKPHARDLGRH- 3677
                +       G   RH+ +  H      D  RHS    G+  G R ++     + +  
Sbjct: 3484 SASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSAGPRTSRNQGSSVSQDS 3543

Query: 3678 EARPHSQPS-------------SAPAMPKKGQPGYPSSAE------YSQPSRASSAYHHA 3718
            +++ HS+ S             SA    + G     S  E      +S  S   S  HHA
Sbjct: 3544 DSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHA 3603

Query: 3719 SDSKKGSRQAHSGPAALQSKAEPQAQPQLQG----RQAAPGPQQSQSPSSRQIPSGAASR 3774
             +S  G + A S   A  S  E       Q     R +  G  Q+ S        G++  
Sbjct: 3604 ENSS-GGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGS 3662

Query: 3775 QPQTQQQQQGLGLQPPQQALTQARLQQQS-QPTTRGSAPAASQPAGKPQPGPSTATGPQP 3833
            Q    +            A  QA   QQS Q +TRG +   S  +G      ST    + 
Sbjct: 3663 QASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSES 3722

Query: 3834 AGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGA 3883
            A       T G +G+     +  +  +    G        G+R GG  G+
Sbjct: 3723 AHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGS 3772



 Score = 53.1 bits (126), Expect = 5e-06
 Identities = 160/772 (20%), Positives = 250/772 (32%), Gaps = 129/772 (16%)

Query: 3172 SSAPSETSYSGPAVSSGYEQGKVPE--VPRAGDRGSVSQSPAPTYPSD-SHYTSLEQNVP 3228
            S    +T    P  S G  QG   E  V R+G  GS          SD SH  S  ++  
Sbjct: 509  SQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSAS 568

Query: 3229 RNYVMIDDISELTKDS------TSTAPDSQRLEPLGPGSSGRPGKEPGEPGVLD------ 3276
            R     +   + T+ S       S+  DS R   +G G S  P     +   +       
Sbjct: 569  RQTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQ 628

Query: 3277 ----------GPTLPCCYARGEEESEEDSYDPRG----KGGHLRSMESNGRPASTHYYGD 3322
                      G      +   +E+S + S  PR     + GH  S +S+ R + T +  +
Sbjct: 629  GHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSS-RKSGTRHTQN 687

Query: 3323 SDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVE 3382
            S     A   +      G +H S+    +A SS+ S          +        +    
Sbjct: 688  SSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQA 747

Query: 3383 SDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSR 3442
            +D   +   + + S+   G+                 Q+ +  S+RD   +     GS  
Sbjct: 748  TDSEGHSEDSDTQSVSGHGQ-------------AGHHQQSHQESARDRSGERSRRSGSFL 794

Query: 3443 SRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMRSQAS 3502
             +  +    E  SSH ++G   G  +                     H + R   R  AS
Sbjct: 795  YQVSTHKQSE--SSHGWTGPSTGVRQGSH------------------HEQARDNSRHSAS 834

Query: 3503 EEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILD 3562
            ++       G+    G P    G +      SH    V      G   H++   +G   D
Sbjct: 835  QD-------GQDTIRGHP----GSSRRGRQGSHHEQSVDRSGHSGSH-HSHTTSQGRS-D 881

Query: 3563 DSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGG--------HAVSSSSQKRGPAR 3614
             S        A    + E    D  R + S   RHH          H+ +   Q  G   
Sbjct: 882  ASRGQSGSRSASRTTRNEEQSRDGSRHSGS---RHHEASSHADISRHSQAGQGQSEGSRT 938

Query: 3615 HSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHG---DHGRHSGRHTGEEPGRRAAKPHA 3671
                      +     H E       SA  +  G   +  RH  RH       RA   H+
Sbjct: 939  SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAGHGHS 998

Query: 3672 RDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQP-SRASSAYHHASDSKKGS----R 3726
             D  R    PH++ SS       GQ         S P  R  S +  ++DS + S    R
Sbjct: 999  ADSSRQSGTPHAETSSG------GQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRR 1052

Query: 3727 QA-----------HSGPAALQSKA-EPQAQPQLQGRQAAPGP-QQSQSPSSRQIPSGAAS 3773
            QA            SG  A  S+    ++  Q        GP QQS   S+R    G + 
Sbjct: 1053 QASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSG 1112

Query: 3774 R------QPQTQQQQQGL-GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPS 3826
            R      Q  T +Q +   G         Q    +Q++ ++R SA    Q   +  PG S
Sbjct: 1113 RSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPG-S 1171

Query: 3827 TATGPQPAGPPRAEQTNGSKGT--AKAPQQGRAPQAQPAPGPGPAGVKAGAR 3876
               G Q +   ++   +G  G+  +    QGR+  +      G +G ++ +R
Sbjct: 1172 RRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASH-----GQSGSRSASR 1218



 Score = 48.9 bits (115), Expect = 1e-04
 Identities = 137/643 (21%), Positives = 226/643 (35%), Gaps = 75/643 (11%)

Query: 3284 YARGEEESEEDSYDPRGKGGHL-RSMESNGRPASTHYYGDSDYR--HGARVEKYGPGPMG 3340
            +++  +   E S   R +G  + +  +S G    +  +  S  R  HG+  E+   G   
Sbjct: 2870 HSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2929

Query: 3341 PKHPSKSLAP---AAISSKRSKHRKQGMEQKISKFSPIEEAKDVESDL-ASYPPPAVSSS 3396
            P+   +  A    +A SS++S  R           S  E+A+    +   S+   +  SS
Sbjct: 2930 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSS 2989

Query: 3397 LVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYGGSSRSRAPSAY--SGEKL 3454
              S        I +G   +      + G S   A  D+  +   S +++ SA+  +G   
Sbjct: 2990 RHSG-------IGHGQASSAVRDSGHRGYSGSQA-SDNEGHSEDSDTQSVSAHGQAGSHQ 3041

Query: 3455 SSHDFSGWGKGYEREREAVERLQKAGPKPSSLSM-----AHSRVRPPMRSQASEEES--P 3507
             SH  S  G+  E    +   L +      S S        +R R   R + +++ S   
Sbjct: 3042 QSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSRHS 3101

Query: 3508 VSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCV 3567
             S  G+    G P    G     +   HS+ D   H       H++   +G   D S   
Sbjct: 3102 ASQYGQDTIRGHPGSSRGGR-QGYHHEHSV-DSSGH---SGSHHSHTTSQGRS-DASRGQ 3155

Query: 3568 VSDSEAYHLGQEETDWFDKPRDARSDRFRHHGG--------HAVSSSSQKRGPARHSYHD 3619
                 A    + E    D  R + S   RHH          H+ +   Q  G  R     
Sbjct: 3156 SGSRSASRTTRNEEQSGDSSRHSVS---RHHEASTHADISRHSQAVQGQSEGSRRSRRQG 3212

Query: 3620 YDEPPEEGLWPHDEGGPGRHASAKEHRHG---DHGRHSGRHTGEEPGRRAAKPHARDLGR 3676
                 +     H E       SA  +  G   +  RH  RH       RA   H+ D  R
Sbjct: 3213 SSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSR 3272

Query: 3677 HEARPHSQPSSAPAMPK-----KGQPGYPSSAEYSQPSRASSAYH------HASDSKKGS 3725
                 H++ SS           +  PG    + + Q   A S+ H       AS + + S
Sbjct: 3273 QSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQ--SADSSRHSGIPRGQASSAVRDS 3330

Query: 3726 RQ-AHSGPAALQSK--AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASR------QP 3776
            R    SG  A  S+  +E      + G   A   QQS   S+R    G + R      Q 
Sbjct: 3331 RHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQV 3390

Query: 3777 QTQQQQQGL-GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG 3835
             T +Q +   G         Q    +Q++ ++R SA    Q   +  PG S+  G Q + 
Sbjct: 3391 STHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPG-SSRRGRQGSH 3449

Query: 3836 PPRAEQTNGSKGT--AKAPQQGRAPQAQPAPGPGPAGVKAGAR 3876
              ++   +G  G+  +    QGR+  ++     G +G ++ +R
Sbjct: 3450 YEQSVDRSGHSGSHHSHTTSQGRSDASR-----GQSGSRSASR 3487



 Score = 47.8 bits (112), Expect = 2e-04
 Identities = 67/281 (23%), Positives = 103/281 (36%), Gaps = 37/281 (13%)

Query: 3601 HAVSSSSQKRGPARHSYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGE 3660
            H  S+  Q R  +RH    +++    G         G H +  E+  G     S      
Sbjct: 3563 HRGSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHA--ENSSGGQAASSHEQARS 3620

Query: 3661 EPGRRAAKPHAR--DLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHA 3718
              G R    H +  D  RH    H Q SSA  +   G  G       S  S+AS +  H+
Sbjct: 3621 SAGERHGSHHQQSADSSRHSGIGHGQASSA--VRDSGHRG-------SSGSQASDSEGHS 3671

Query: 3719 SDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQT 3778
             DS   S  AH            QA P  Q  Q +   +     + R   SG+   Q  T
Sbjct: 3672 EDSDTQSVSAHG-----------QAGPHQQSHQESTRGRS----AGRSGRSGSFLYQVST 3716

Query: 3779 QQQQQGL-GLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
             +Q +   G   P     Q    +Q++ ++R SA    Q   +  PG S   G Q +   
Sbjct: 3717 HEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG-SRRGGRQGSYHE 3775

Query: 3838 RAEQTNGSKGT--AKAPQQGRAPQAQPAPGPGPAGVKAGAR 3876
            ++   +G  G+  +    QGR+  +      G +G ++ +R
Sbjct: 3776 QSVDRSGHSGSHHSHTTSQGRSDASH-----GQSGSRSASR 3811



 Score = 45.1 bits (105), Expect = 0.001
 Identities = 142/681 (20%), Positives = 223/681 (32%), Gaps = 109/681 (16%)

Query: 3285 ARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDS---DYRHGARVEKYGPGPMGP 3341
            +RG+  S   S   R +    +S + +    S H+   S     RH    +    GP   
Sbjct: 1855 SRGQSGSRSVSRQTRNEK---QSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTS 1911

Query: 3342 KHPSKSLAPAAISSKRSK--HRKQGMEQKISKFSPIEEAKDVE-------SDLASYPPPA 3392
            ++   S++  + S   S+   R  G   +    S  E+++D          D A +   A
Sbjct: 1912 RNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSA 1971

Query: 3393 VSSSLVSRGRKFQDEITYGLKKNVYEQQKY-----YGMSSRDAVEDDRIYGGSSRSRAPS 3447
             SS     G +  +  + G   + +EQ +      +G   +    D   + G    +A S
Sbjct: 1972 DSSR--QSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSSRHSGIGHGQASS 2029

Query: 3448 A--------YSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSS-------LSMAHSR 3492
            A        YSG + S  +    G   + + ++V    KAGP   S        S   S 
Sbjct: 2030 AVRDSGHRGYSGSQASDSE----GHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSG 2085

Query: 3493 VRPPMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHA 3552
                   Q S  E   S  G+  P+ G          Q  S HS     +  +D  R H 
Sbjct: 2086 RSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHS---ASQEGQDTIRGHP 2142

Query: 3553 YKREEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARS-------------------- 3592
                 G     SH   S   + H G   +    + R   S                    
Sbjct: 2143 GPSRGGR--QGSHQEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSG 2200

Query: 3593 DRFRHHGGHAVSSSS-------------QKRGPARHSYHDYDEPPEEGLWPHDEGGPGRH 3639
            D  RH G H   +SS             Q  GP            +     H E    R 
Sbjct: 2201 DGSRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRS 2260

Query: 3640 ASAKEHRHG-------DHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSA---- 3688
             SA  + HG       D  RH   H  +  G   +   +R  G H A   S   +A    
Sbjct: 2261 GSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHE 2320

Query: 3689 PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDS--KKGSRQAHSGPAALQSKAEPQ-AQP 3745
             A    G+       + +  SR S   H  + S  +    +  SG  A  S+   + +  
Sbjct: 2321 QARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDT 2380

Query: 3746 QLQGRQAAPGP-QQSQSPSSRQIPSGAASR------QPQTQQQQQGL-GLQPPQQALTQA 3797
            Q        GP QQS   S+R   +G + R      Q  T +Q +   G         Q 
Sbjct: 2381 QSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQG 2440

Query: 3798 RLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGT--AKAPQQG 3855
               +Q++ ++R S     Q      PG S++ G Q +   +    +G  G+  +    QG
Sbjct: 2441 SHHKQARDSSRHSTSQEGQDTIHGHPG-SSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQG 2499

Query: 3856 RAPQAQPAPGPGPAGVKAGAR 3876
            R+  +      G +G ++ +R
Sbjct: 2500 RSDASH-----GHSGSRSASR 2515



 Score = 44.7 bits (104), Expect = 0.002
 Identities = 135/653 (20%), Positives = 216/653 (33%), Gaps = 95/653 (14%)

Query: 3287 GEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDSDYRHG--ARVEKYGPGPMGPKHP 3344
            G   +   +YD    G   R   S+   AS+  + DS  RH    + +  GP    P+  
Sbjct: 2185 GSRSASRKTYDKEQSGDGSRHSGSHHHEASS--WADSS-RHSLVGQGQSSGPRTSRPRGS 2241

Query: 3345 SKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVE-------SDLASYPPPAVSSSL 3397
            S S    +        R+ G   +    S  E+++D          D A +   A SS  
Sbjct: 2242 SVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSAESSR- 2300

Query: 3398 VSRGRKFQDEITYGLKKNVYEQQKY-----YGMSSRDAVEDDRIYGGSSRSRAPSAY--S 3450
               G    +  + G   + +EQ +      +G   + + +  R + G    +A SA   S
Sbjct: 2301 -QSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSR-HSGIGHGQASSAVRDS 2358

Query: 3451 GEKLSSHDFSGWGKGY--EREREAVERLQKAGPKPSSLSMAHSRVRPPMRS--------Q 3500
            G + SS   +   +G+  + + ++V    +AGP   S     +R R   RS        Q
Sbjct: 2359 GHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQS-HQESTRGRSAGRSGRSGSFLYQ 2417

Query: 3501 ASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKREEGYI 3560
             S  E   S  GR          G  T  +  S H      +  +D  R H+  +E    
Sbjct: 2418 VSTHEQSESAHGRT---------GTSTGGRQGSHH------KQARDSSR-HSTSQEG--- 2458

Query: 3561 LDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDY 3620
                     D+   H G           +   DR  H G H   ++SQ R  A H +   
Sbjct: 2459 --------QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGS 2510

Query: 3621 DEPPEEGLWPHDEGGPGRHASAKEHR---HGDHGRHSGRHTGEEPGRRAAKPHARDLGR- 3676
                 +       G   RH+ ++ H      D   HS    G+  G R ++       + 
Sbjct: 2511 RSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPRTSRNWGSSFSQD 2570

Query: 3677 HEARPHSQPS-------------SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKK 3723
             +++ HS+ S             SA    + G   +P S    Q  RA   +   S  + 
Sbjct: 2571 SDSQGHSEDSERWSGSASRNHHGSAQEQLRDGS-RHPRS---HQEDRAGHGHSADSSRQS 2626

Query: 3724 GSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQ 3783
            G+R   +      + +  QA+     R  +   Q + S     I  G AS   +    + 
Sbjct: 2627 GTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRG 2686

Query: 3784 GLGLQPPQ-------------QALTQARLQQQS-QPTTRGSAPAASQPAGKPQPGPSTAT 3829
              G Q                 A  QA   QQS Q + RG +   S  +G      ST  
Sbjct: 2687 YSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHE 2746

Query: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPG 3882
              + +       T G +G+     Q  +  +    G        G+  GG  G
Sbjct: 2747 QSESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQG 2799



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 86/376 (22%), Positives = 122/376 (32%), Gaps = 55/376 (14%)

Query: 905  YEELLPEGGSAEATDGSGTLQG----------GLRRFKTIELNSTGSYGHELDLGQG-PD 953
            +E+       + + DG  T++G          G    ++++ +    Y H     QG  D
Sbjct: 1470 HEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSD 1529

Query: 954  PSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRR 1013
             S  +         T + E    G   S      PS  +G+S  S     E + S  SRR
Sbjct: 1530 ASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQGESAGSKTSRR 1589

Query: 1014 QRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARK 1073
            Q      Q R +            E  SE+ E R E          RE  +   R+    
Sbjct: 1590 QG-SSVSQDRDS------------EGHSEDSERRSESASRNHYGSAREQSRHGSRNP--- 1633

Query: 1074 TRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLD 1133
              R  +E RA        +  S     E +S      QAA  +E  RSS  E   S    
Sbjct: 1634 --RSHQEDRASHGHSAESSRQSGTRHAETSSG----GQAASSQEQARSSPGERHGSRHQQ 1687

Query: 1134 SEAEALDGGPSRLYKS---GSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEE 1190
            S   + D G  R   S   G   N  +  S  S +E  S  S T S    + +  +A   
Sbjct: 1688 SADSSTDSGTGRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQS----VSAHGQAGPH 1743

Query: 1191 MMRKAELLQRQQGQAAGARG--------------PHGGPSQPTGPRGLGSFEY-QDTTDR 1235
                 E  + Q G+ +G  G               HG     TG R     E  +D++  
Sbjct: 1744 QQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRH 1803

Query: 1236 EYGQAAQPAAEGTPAS 1251
               Q  Q    G P S
Sbjct: 1804 SASQEGQDTIRGHPGS 1819



 Score = 40.4 bits (93), Expect = 0.035
 Identities = 67/288 (23%), Positives = 101/288 (35%), Gaps = 52/288 (18%)

Query: 3541 QEHVKDG---PRAHAYKRE-EGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRF- 3595
            QE ++DG   PR+H   R   G+  D S    +       G +     ++ R +  +R  
Sbjct: 2596 QEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHG 2655

Query: 3596 ----------RHHG-GHAVSSSSQK----RGPARHSYHDYDEPPEEG----LWPHDEGGP 3636
                      RH G GH  +SS+ +    RG +     D +   E+     +  H + G 
Sbjct: 2656 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS 2715

Query: 3637 GR--HASAKEHRHGDHGRHSGRH----------------TGEEPGRRAAKPH--ARDLGR 3676
             +  H  +   R G+   HSG                  TG     R    H  A+D  R
Sbjct: 2716 HQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDSSR 2775

Query: 3677 HEARPHSQPS--SAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAA 3734
            H A    Q +    P   + G+ GY    E+S  S   S  HH+  + +G   A  G   
Sbjct: 2776 HSASQDGQDTIRGHPGSSRGGRQGYHH--EHSVDSSGHSGSHHSHTTSQGRSDASRG--- 2830

Query: 3735 LQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQ 3782
             QS +   ++      Q+  G + S S           SR  Q  Q Q
Sbjct: 2831 -QSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQ 2877


>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
            [Homo sapiens]
          Length = 1412

 Score = 72.8 bits (177), Expect = 6e-12
 Identities = 166/820 (20%), Positives = 282/820 (34%), Gaps = 109/820 (13%)

Query: 10   GAGDGPLPPGGAGPGPGPGPGPGAGK---------PPSAPAGGGQLPAAGA-----ARST 55
            G G GP+PPG  GP     P    GK           S+ +  G++P A A     +   
Sbjct: 441  GKGAGPVPPGKVGPAT---PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN 497

Query: 56   AVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQA-SATTPGHESPRETRA 114
             +   P   P  GP    G  + ++  ++P+ N  ++  +   A S   P   +  + + 
Sbjct: 498  ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP 557

Query: 115  QGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPY-SVPQIAPLPSSTLCPIC 173
                 Q    P++T    S      R  + +P +  T TSP  S P +A     T  P  
Sbjct: 558  ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA---GGTQRPAE 614

Query: 174  KTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA 233
             +S    + S+    T            G        QVK     +  ++ +LG      
Sbjct: 615  DSSSSEESDSEEE-KTGLAVTVGQAKSVGKG-----LQVK---AASVPVKGSLGQGTAPV 665

Query: 234  PRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQA 293
               K+      P ++   +  ++     ++E         P   +    +  +   PA A
Sbjct: 666  LPGKT-----GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720

Query: 294  AAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAP-----------AKSATAVPAGLGATEQT 342
             AP   G +S      T  + A+ R P+   P           A+   +VP+   A    
Sbjct: 721  RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780

Query: 343  QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGS 402
             +  TG     G+S     S     + EA+T  Q  PS  T +I    A  +  P+    
Sbjct: 781  AQAQTGPEEDSGSSEEESDS-----EEEAETLAQVKPSGKTHQIRAALAPAKESPR---- 831

Query: 403  GPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAA---------A 453
              G  P P  KT P A        G    +G ++       E  AA  +A          
Sbjct: 832  -KGAAPTPPGKTGPSAAQA-----GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 885

Query: 454  KPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCL 513
             P   P   A  P      +   K+ A+ +T  +   +       +    ++  T+    
Sbjct: 886  DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE-------SEDEDVIPATQ---- 934

Query: 514  NCQTKRLLEGSLGEPTPLP---PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPA 570
             C T  +    +  PT  P   P  S      +   +  +   KQ+GP    Q S   PA
Sbjct: 935  -CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGP--ATQVSKKNPA 991

Query: 571  KASPLSTKASPLPSKASPQAKPLRASEPSK-------TPSSVQEKKTRVPTKAEPMPKPP 623
                       L  KAS    P+  ++PS        T  +   + T V  K     + P
Sbjct: 992  SLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1051

Query: 624  --PETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE-AEDLVGKPYSQDASRSPQSL 680
              PE       P+       +  ++   +   E P+G + A  LVG   S+  +   ++ 
Sbjct: 1052 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETA 1111

Query: 681  SDTGYSSDGISSSQSEITGVVQQEVEQLDS--AGVTGPHPPSPSEIHKVGS--------S 730
            +++    D ++ SQS ++G +   +   +S  +  T     SPS    + +         
Sbjct: 1112 AESS-EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQE 1170

Query: 731  MRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEA 770
             +P   A  L+P    K  +SGT  ++ ++P   +  P+A
Sbjct: 1171 AKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQA 1210



 Score = 63.9 bits (154), Expect = 3e-09
 Identities = 208/1056 (19%), Positives = 338/1056 (32%), Gaps = 167/1056 (15%)

Query: 882  RPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGT--------------LQGG 927
            R   ++E AAL  ++   +      E   E   AEA     T              L   
Sbjct: 61   RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120

Query: 928  LRRFKTIELNSTGSYGHEL----------DLGQGPDPSLDREPELEMESLTGSPEDRSRG 977
            ++     E    G  G+ +          +L  G  P    EP      ++ + E+ S  
Sbjct: 121  MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180

Query: 978  EHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHG------ 1031
               +   A     ++G + +S       SD +    +  E+  Q R A   + G      
Sbjct: 181  AFGAA--AKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGA 238

Query: 1032 -PLLP----TIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRAQRR 1086
             P  P     +   ++  +  E+ E   E+    E E    ++  +     K        
Sbjct: 239  TPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS 298

Query: 1087 RERSKTPPSNLSPIEDAS--PTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPS 1144
                ++P    +P       P     QA + EE  +SS  E        ++A+     P 
Sbjct: 299  APAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQ 358

Query: 1145 RLYKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQ 1204
                S      P   +  +P      ++     G+  + +  + EE     E L      
Sbjct: 359  VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAA 418

Query: 1205 AAGARG--PHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQ 1262
                 G  P   P+   G   LG            G    P  +  PA+  A V +    
Sbjct: 419  QVKPLGKSPQVKPASTMGMGPLGK-----------GAGPVPPGKVGPATPSAQVGKWEED 467

Query: 1263 TSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVS 1322
            +  S      +S  ++  A    +EK   N   A        G P   G    Q+ A   
Sbjct: 468  SESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKP 527

Query: 1323 FSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPA 1382
                 SS+ S      +       A + +  LK+  + A P   +            T A
Sbjct: 528  MDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTN------------TTA 575

Query: 1383 TTAVAPCPAGL--PRGYMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPS 1440
            +  VAP   G   PR   T  SPAGS    SP+    +    P   +  S+  D  +  +
Sbjct: 576  SAKVAPVRVGTQAPRKAGTATSPAGS----SPAVAGGT--QRPAEDSSSSEESDSEEEKT 629

Query: 1441 GLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRA 1500
            GLA     A+      S G+G             ++S P+  S    +    PGK GP  
Sbjct: 630  GLAVTVGQAK------SVGKG---------LQVKAASVPVKGSLGQGTAPVLPGKTGPTV 674

Query: 1501 T---AEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFM 1557
            T   AE    + S    SD   +  +P       + TQ    P+  R    + +  AP  
Sbjct: 675  TQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGK 734

Query: 1558 VITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPR 1617
            V+T A+ A  +              SP++ +P       +T  +         GP   P 
Sbjct: 735  VVTAAAQAKQR--------------SPSKVKPPVRNPQNSTVLA--------RGPASVPS 772

Query: 1618 VPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPI 1677
            V  A A    A  G    P E+          G+S  E         +  ++ + K    
Sbjct: 773  VGKAVATAAQAQTG----PEED---------SGSSEEESDSEEEAETLAQVKPSGK---- 815

Query: 1678 ILTDQGMDLTSLAVEARKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMA 1737
              T Q     + A E+ + G A  P PG+      P       Q+ +  ++  + S   A
Sbjct: 816  --THQIRAALAPAKESPRKGAAPTP-PGKTG----PSAAQAGKQDDSGSSSEESDSDGEA 868

Query: 1738 SSVFMAQQ--KQPVVYGDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPR 1795
             +   + Q  K P+++ DP +          SP   A      QA  T          PR
Sbjct: 869  PAAVTSAQVIKPPLIFVDPNR----------SPAGPAATPAQAQAAST----------PR 908

Query: 1796 EAKFARYNLPNQVAPLARRDVL-ITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHAL 1854
            +A+ +     +  +     DV+  TQ  T    G++   V  P A P  A  A +     
Sbjct: 909  KARASESTARSSSSESEDEDVIPATQCLTP---GIRTNVVTMPTAHPRIAPKASMAG--- 962

Query: 1855 PGARKPHTVVVQMGEGTAGTVTTLLPEEPAGALDLT 1890
              +    +  +  G+   G  T +  + PA +L LT
Sbjct: 963  -ASSSKESSRISDGKKQEGPATQVSKKNPA-SLPLT 996



 Score = 62.4 bits (150), Expect = 9e-09
 Identities = 66/259 (25%), Positives = 95/259 (36%), Gaps = 41/259 (15%)

Query: 3665 RAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYP------SSAEYSQPSRASSAYHHA 3718
            RAA   A+      A P + P  A A+  + + G P      SS E S     + A    
Sbjct: 224  RAASAPAKGTPGKGATP-APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKAL 282

Query: 3719 SDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQT 3778
              +K   + +  G A+  +K  P+       + AAP P     P+  +  +G      Q+
Sbjct: 283  LQAKASGKTSQVGAASAPAKESPR-------KGAAPAPPGKTGPAVAKAQAGKREEDSQS 335

Query: 3779 QQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPR 3838
              ++     + P QA    +  Q        SAPA   P     P P   TGP  A    
Sbjct: 336  SSEESDSEEEAPAQAKPSGKAPQ----VRAASAPAKESPRKGAAPAPPRKTGPAAAQVQV 391

Query: 3839 AEQTNGSKGT----------------AKAPQQGRAPQAQPAP--GPGPAGVKAGARPGG- 3879
             +Q   S+ +                A+    G++PQ +PA   G GP G  AG  P G 
Sbjct: 392  GKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGK 451

Query: 3880 ----TPGAPAGQPGADGES 3894
                TP A  G+   D ES
Sbjct: 452  VGPATPSAQVGKWEEDSES 470



 Score = 61.6 bits (148), Expect = 1e-08
 Identities = 196/941 (20%), Positives = 308/941 (32%), Gaps = 169/941 (17%)

Query: 3036 PATAAAPATP--SGPTAFQQPRFQPPAPQYSAGS-GGPTQNGFPAHQA---------PTY 3083
            P   A PA P  +G  A Q    +P     S+      ++   PA +A          + 
Sbjct: 234  PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 293

Query: 3084 PGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQ 3143
             G ++ PA   P   + PA PG         TG                  PA ++A   
Sbjct: 294  VGAASAPAKESPRKGAAPAPPG--------KTG------------------PAVAKAQAG 327

Query: 3144 KPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDR 3203
            K  + S +  E+    + E   +   P   AP   + S PA  S   +G  P  PR    
Sbjct: 328  KREEDSQSSSEES--DSEEEAPAQAKPSGKAPQVRAASAPAKESP-RKGAAPAPPRKTGP 384

Query: 3204 GSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSG 3263
             + +Q        DS  +S E +  R  +   + +++     S  P  +    +G G  G
Sbjct: 385  AA-AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKS--PQVKPASTMGMGPLG 441

Query: 3264 RPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDS 3323
            + G  P  PG +   T      + EE+SE  S +         S  S+G   +      +
Sbjct: 442  K-GAGPVPPGKVGPATPSAQVGKWEEDSESSSEES--------SDSSDGEVPTA--VAPA 490

Query: 3324 DYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVES 3383
              +    + +  P     K P +   P A+  K  K        +       E +   +S
Sbjct: 491  QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE-------ESSDSADS 543

Query: 3384 DLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYY------------GMSSRDAV 3431
            + A   P A++++      K         K N     K              G ++  A 
Sbjct: 544  EEA---PAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 600

Query: 3432 EDDRIYGGSSRSRAPSAYSGEKLSSHDFSGW----------GKGYEREREAVERLQKAG- 3480
                + GG+ R    S+ S E  S  + +G           GKG + +  +V      G 
Sbjct: 601  SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 660

Query: 3481 ------PKPSSLSMAHSRVRPPMRSQASEEESP-----VSPL------------GRPRPA 3517
                  P  +  ++   +      S++SEEES       SP               P  A
Sbjct: 661  GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 720

Query: 3518 GGPLPPGGDTCP-------QFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSD 3570
              P   G  + P             S   V+  V++   +    R    +      V + 
Sbjct: 721  RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780

Query: 3571 SEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWP 3630
            ++A    +E++   ++  D+  +        A    S K    R +     E P +G  P
Sbjct: 781  AQAQTGPEEDSGSSEEESDSEEEAETL----AQVKPSGKTHQIRAALAPAKESPRKGAAP 836

Query: 3631 HDEG--GPGRHASAKEHRHGDHGRHSGRHTGEEPGR----RAAKPHAR--DLGRHEARPH 3682
               G  GP    + K+   G     S    GE P      +  KP     D  R  A P 
Sbjct: 837  TPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 895

Query: 3683 SQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQ 3742
            + P+ A A         P  A  S+ +  SS+     +    + Q  +          P 
Sbjct: 896  ATPAQAQAAST------PRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT 949

Query: 3743 AQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQ 3802
            A P++  + +  G   S S  S +I  G     P TQ  ++     P    LTQA L+  
Sbjct: 950  AHPRIAPKASMAGA--SSSKESSRISDGKKQEGPATQVSKKN----PASLPLTQAALKVL 1003

Query: 3803 SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA--PQQGRAPQA 3860
            +Q  +    P A     +P  G  +A G  PA  P++     +KGT K   P+     QA
Sbjct: 1004 AQKASEAQPPVART---QPSSGVDSAVGTLPATSPQSTSVQ-AKGTNKLRKPKLPEVQQA 1059

Query: 3861 QPAP-------------------GPGPAGVK-AGARPGGTP 3881
              AP                   G GP G K A    G TP
Sbjct: 1060 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTP 1100



 Score = 60.1 bits (144), Expect = 4e-08
 Identities = 63/269 (23%), Positives = 98/269 (36%), Gaps = 38/269 (14%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            +G+ P R++A+P A      E     +  S PA     +PG  S+ +    S  +S    
Sbjct: 153  SGKSP-RKSAEPSANTTLVSETE---EEGSVPAFGAAAKPGMVSAGQADSSSEDTS---- 204

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQ 3777
             S S +   +  +    LQ +A         G+ A P P       + Q  +G      +
Sbjct: 205  -SSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSE 263

Query: 3778 TQQQQQGLGLQ--PPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAG 3835
            +  ++     +  P  +AL QA+   ++      SAPA   P     P P   TGP  A 
Sbjct: 264  SSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAK 323

Query: 3836 PPRAEQTNGSKGT-----------AKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAP 3884
                ++   S+ +           A+A   G+APQ + A  P     + GA P     AP
Sbjct: 324  AQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-----AP 378

Query: 3885 AGQPGADGESVFSKILPGGAAEQAGKLTE 3913
              + G           P  A  Q GK  E
Sbjct: 379  PRKTG-----------PAAAQVQVGKQEE 396



 Score = 57.4 bits (137), Expect = 3e-07
 Identities = 253/1307 (19%), Positives = 409/1307 (31%), Gaps = 211/1307 (16%)

Query: 21   AGPGPGPGPGPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRL 80
            A   P  G  PG G  P+ P   G    A A+++ A  P                +    
Sbjct: 225  AASAPAKGT-PGKGATPAPPGKAG----AVASQTKAGKPEED---SESSSEESSDSEEET 276

Query: 81   DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGR 140
               + L   +A+  T +  +A+ P  ESPR+  A  P G+   GP        + +   +
Sbjct: 277  PAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGK--TGPAVAKAQAGKREEDSQ 334

Query: 141  SPSVSPDRGSTPTSPYSVPQIAPLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQ 200
            S S   D      +       AP   +   P  ++    + P+ P               
Sbjct: 335  SSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPR-------------- 380

Query: 201  CGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGK 260
                  P   QV+            +G     +  S  +      AL+  ++   +PLGK
Sbjct: 381  ---KTGPAAAQVQ------------VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGK 425

Query: 261  PDQERSRGPGGPQPGSRQAETARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPP 320
              Q +     G  P  + A         GP     PP  G+V P  P        E    
Sbjct: 426  SPQVKPASTMGMGPLGKGA---------GP----VPP--GKVGPATPSAQVGKWEEDSES 470

Query: 321  AGEAPAKSATA-VPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAP 379
            + E  + S+   VP  +   ++   G          ++L    T    +      G  A 
Sbjct: 471  SSEESSDSSDGEVPTAVAPAQEKSLG----------NILQAKPTSSPAKGPPQKAGPVAV 520

Query: 380  SKGTPKIVFNDASKEAGPKPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPK 439
                 K + N  S E       S   P     A+ +P  ++       A PK   TT+  
Sbjct: 521  QVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTK---ACPKKTNTTASA 577

Query: 440  H---GRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLC 496
                 R   QA  KA           A+    Q      S S  + +      L V    
Sbjct: 578  KVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAV---- 633

Query: 497  GFNPTPHLVEKTEWLCLNCQTKRL---LEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPL 553
                    V + + +    Q K     ++GSLG+ T    P    P V      +     
Sbjct: 634  -------TVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTV------TQVKAE 680

Query: 554  KQKGPQGLGQPSGPLPAKASPLSTKASPLPSKASPQAKPLRA-------SEPSKTPSSVQ 606
            KQ+  +   + S    A ASP   K S   ++A       RA       S P K  ++  
Sbjct: 681  KQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAA 740

Query: 607  EKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVG 666
            + K R P+K +P  + P  +T     P     V +A       +  PE   G   E+   
Sbjct: 741  QAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE--- 797

Query: 667  KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSA----GVTGPHPPSPS 722
                 D+    ++L+    S     + Q        +E  +  +A    G TGP      
Sbjct: 798  ----SDSEEEAETLAQVKPSG---KTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAG 850

Query: 723  EIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILE 782
            +    GSS      + G AP        +     Q  +P  + + P    +         
Sbjct: 851  KQDDSGSSSEE-SDSDGEAP--------AAVTSAQVIKPPLIFVDPNRSPAGPAATP--A 899

Query: 783  EDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDF 842
            + + ++  R+ R  + TA SS            E   E  +       P     +     
Sbjct: 900  QAQAASTPRKARASESTARSSSS----------ESEDEDVIPATQCLTPGIRTNVVTMPT 949

Query: 843  MRRQILEMS--AEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHN 900
               +I   +  A   + +E    + G+      TQ     P   P  + A     +    
Sbjct: 950  AHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASE 1009

Query: 901  ATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREP 960
            A        P  G   A    GTL     +  +++   T                  R+P
Sbjct: 1010 AQPPVARTQPSSGVDSAV---GTLPATSPQSTSVQAKGTNKL---------------RKP 1051

Query: 961  EL-EMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEA 1019
            +L E++  T +PE     E SS   +S+ S   G  P    S       +PSR + L E 
Sbjct: 1052 KLPEVQQATKAPESSDDSEDSS--DSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVE- 1108

Query: 1020 KQQRKARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKE 1079
                            T  +SSE++ +   + LL                T   T  + +
Sbjct: 1109 ---------------ETAAESSEDDVVAPSQSLLSGY------------MTPGLTPANSQ 1141

Query: 1080 ELRAQRRRERSKTPPSNLSPIEDASPTEELR--QAAEMEELHRSSCSEYSPSPSLDSEAE 1137
              +A  + + S +  S L+  +D    +E +  QAA M           SP       A 
Sbjct: 1142 ASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGM----------LSPKTGGKEAAS 1191

Query: 1138 ALDGGPSRLYKSGSEYNLPTFMSLYSP-TETPSGSSTTPSSGRPLKSAEEAYEEMMRKAE 1196
                  SR  K G+     + ++L S  T+   G         PL  A+     +    E
Sbjct: 1192 GTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPW------PLNEAQVQASVVKVLTE 1245

Query: 1197 LLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAV 1256
            LL++++ +              +  R L   +    T R   +    A EG  AS    V
Sbjct: 1246 LLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEAS----V 1301

Query: 1257 YEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQ 1303
              E   T+      R  +S D+     +KK K  L ++ A  +P ++
Sbjct: 1302 SPEKTSTTSKGKAKRDKASGDV----KEKKGKGSLGSQGAKDEPEEE 1344



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 236/1228 (19%), Positives = 404/1228 (32%), Gaps = 230/1228 (18%)

Query: 586  ASPQAKPLRASEPSKTPSSVQEKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAE-P 644
            A+ QAK  R S+P  T  S +E++      A+           TP      S V  A+ P
Sbjct: 69   AALQAKKTRVSDPISTSESSEEEEEAEAETAK----------ATPRLASTNSSVLGADLP 118

Query: 645  ATPVVKAVPEAPKGGEAEDLVGKPYSQD------ASRSPQSLSDTGYSSDGISSSQSEIT 698
            ++   KA  E  K G+  + +  P +        + +SP+  ++   ++  +S ++ E  
Sbjct: 119  SSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEE-- 176

Query: 699  GVVQQEVEQLDSAGVTGPHPPSPSEIHKVGS--------SMRPLLQAQGLAPSERSKPLS 750
            G V           V+     S SE     S        +   +LQ +  +   +  P  
Sbjct: 177  GSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTP-G 235

Query: 751  SGTGEEQKQRPHSLSITPEAFDSDEELEDILEEDEDSAEWRRRREQQDTAESSDDFGS-Q 809
             G       +  +++   +A   +E+ E   EE  DS E     +    A++S       
Sbjct: 236  KGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 295

Query: 810  LRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGL 869
                  ++S   G +P PP     A                S E D+ EE        G 
Sbjct: 296  AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 355

Query: 870  AKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGLR 929
            A        P  +  P +  A  P R+      TG      + G  E    S + +    
Sbjct: 356  APQVRAASAP-AKESPRKGAAPAPPRK------TGPAAAQVQVGKQEEDSRSSSEESDSD 408

Query: 930  RFKTIELNSTGSYGHELDLGQGPDPSLDREPELEMESLTG-SPEDRSRGEHSSTLPASTP 988
            R     +N+                 L + P+++  S  G  P  +  G      P    
Sbjct: 409  REALAAMNA------------AQVKPLGKSPQVKPASTMGMGPLGKGAG------PVPPG 450

Query: 989  SYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELRE 1048
                 T    +   EEDS+SS                            E+SS+  +   
Sbjct: 451  KVGPATPSAQVGKWEEDSESSS---------------------------EESSDSSDGEV 483

Query: 1049 EEELLREQEK-MREVEQQRIRSTARKTRRDKE-ELRAQRRRERSKTPPSNLSPIEDASPT 1106
               +   QEK +  + Q +  S+  K    K   +  Q + E+         P++++  +
Sbjct: 484  PTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEK---------PMDNSESS 534

Query: 1107 EELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTE 1166
            EE   +A+ EE   +  +  +       + +A    P +   + S    P  +   +P +
Sbjct: 535  EESSDSADSEEAPAAMTAAQAKPALKIPQTKAC---PKKTNTTASAKVAPVRVGTQAPRK 591

Query: 1167 -----TPSGSSTTPSSG--RPLK---SAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPS 1216
                 +P+GSS   + G  RP +   S+EE+  E  +    +   Q ++ G         
Sbjct: 592  AGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVG--------- 642

Query: 1217 QPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSR 1276
                 +GL             GQ   P   G              +T  ++ +++     
Sbjct: 643  -----KGLQVKAASVPVKGSLGQGTAPVLPG--------------KTGPTVTQVKAEKQE 683

Query: 1277 DLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAPVSFSTPTSSDSSGGRV 1336
            D   +E++              D  +    P    TS  +  A  + +   +  + G   
Sbjct: 684  DSESSEEES-------------DSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 730

Query: 1337 IPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRG 1396
             P   VT     + + P K+     +P +                 +T +A  PA +P  
Sbjct: 731  APGKVVTAAAQAKQRSPSKVKPPVRNPQN-----------------STVLARGPASVPSV 773

Query: 1397 YMTPASPAGSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQA-PSGLAAAGRAAREKPLS 1455
                A+ A ++  P   S     G S   ++   + E L Q  PSG     RAA   P  
Sbjct: 774  GKAVATAAQAQTGPEEDS-----GSSEEESDSEEEAETLAQVKPSGKTHQIRAAL-APAK 827

Query: 1456 ASDGEGGTPQPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPAS 1515
             S  +G  P P       A+ +     S  S   + S G+  P A        P P    
Sbjct: 828  ESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGE-APAAVTSAQVIKP-PLIFV 885

Query: 1516 DMPRSPGAPTPSPMVAQGTQTPHR----PSTPRLVWQESSQE------------------ 1553
            D  RSP  P  +P  AQ   TP +     ST R    ES  E                  
Sbjct: 886  DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVV 945

Query: 1554 ---------APFMVITLASDASSQTRMVHASASTSPLCSPTETQPTTHGYSQTTPPSVSQ 1604
                     AP   +  AS +   +R+        P    ++  P +   +Q     ++Q
Sbjct: 946  TMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ 1005

Query: 1605 LPPEPPGPPGFPRVPSAGADGPLALYGWGALPAENISLCRISSVPGTSRVEPGPRTPGTA 1664
               E   PP     PS+G D  +     G LPA +     + +  GT+++   P+ P   
Sbjct: 1006 KASEAQ-PPVARTQPSSGVDSAV-----GTLPATSPQSTSVQA-KGTNKLRK-PKLP--- 1054

Query: 1665 VVDLRTAVK-PTPIILTDQGMDLTSLAVE-------ARKYGLALDPIPGRQSTAVQPLVI 1716
              +++ A K P     ++   D +S + E       A+     + P P R  T V+    
Sbjct: 1055 --EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLVGPTPSRTETLVEETAA 1112

Query: 1717 -----NLNAQEHTFLATATTVSITMASS 1739
                 ++ A   + L+   T  +T A+S
Sbjct: 1113 ESSEDDVVAPSQSLLSGYMTPGLTPANS 1140



 Score = 48.5 bits (114), Expect = 1e-04
 Identities = 212/1113 (19%), Positives = 365/1113 (32%), Gaps = 205/1113 (18%)

Query: 278  QAETARATSVPGPAQAAAPP-EVGRVSPQ-----PPQPTKPSTAEPRPPAGEAPAKSATA 331
            +A +A A   PG     APP + G V+ Q     P + ++ S+ E      E PA  A  
Sbjct: 224  RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 283

Query: 332  VPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDA 391
                 G T Q             AS   + S      P    +  PA +K        D+
Sbjct: 284  QAKASGKTSQVG----------AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 333

Query: 392  --------SKEAGP---KPLGSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKH 440
                    S+E  P   KP G  P    A  A  +   R G    P   P+  G  + + 
Sbjct: 334  QSSSEESDSEEEAPAQAKPSGKAPQVRAA-SAPAKESPRKGAAPAP---PRKTGPAAAQV 389

Query: 441  GRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNP 500
               + +  S+++++     +E A+  +  A++    KSP         +++  +  G  P
Sbjct: 390  QVGKQEEDSRSSSEESDSDRE-ALAAMNAAQVKPLGKSP---------QVKPASTMGMGP 439

Query: 501  TPHLVEKTEWLCLNCQTKRLLEGSLGEPT-PLPP----PTSQQPPVGAPHRASGTSPLKQ 555
                                    LG+   P+PP    P +    VG     S +S  + 
Sbjct: 440  ------------------------LGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEES 475

Query: 556  KGPQGLGQPSGPLPAK---------ASPLSTKASPLPSKASPQAKPLRASEPSKTPSSVQ 606
                    P+   PA+         A P S+ A   P KA P A  ++A +P     S +
Sbjct: 476  SDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE 535

Query: 607  EKKTRVPTKAEP------MPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGE 660
            E      ++  P        KP  +   T A PK K+    +    PV        K G 
Sbjct: 536  ESSDSADSEEAPAAMTAAQAKPALKIPQTKACPK-KTNTTASAKVAPVRVGTQAPRKAGT 594

Query: 661  AEDLVG-KPYSQDASRSPQSLSDTGYSSDGISSSQSEITGVVQQEVEQLDSAGVTGPHPP 719
            A    G  P     ++ P   S +   SD    S+ E TG+    V Q  S G       
Sbjct: 595  ATSPAGSSPAVAGGTQRPAEDSSSSEESD----SEEEKTGLA-VTVGQAKSVG------- 642

Query: 720  SPSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITP-EAFDSDEELE 778
                              +GL     S P+    G+       +  + P +   +  +++
Sbjct: 643  ------------------KGLQVKAASVPVKGSLGQ------GTAPVLPGKTGPTVTQVK 678

Query: 779  DILEEDEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELT 838
               +ED +S+E     E+ D+ E++    S  +       ++   +P   + P+    ++
Sbjct: 679  AEKQEDSESSE-----EESDSEEAA---ASPAQVKTSVKKTQAKANPAAARAPSAKGTIS 730

Query: 839  DEDFMRRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLP 898
                   +++  +A+             R          GP   P   +  A   +    
Sbjct: 731  APG----KVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ---- 782

Query: 899  HNATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDR 958
              A TG EE    G S E +D            +T+         H++     P     R
Sbjct: 783  --AQTGPEE--DSGSSEEESDSE-------EEAETLAQVKPSGKTHQIRAALAPAKESPR 831

Query: 959  EPELEMESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLE--------EDSDSSP 1010
            +           P     G+   +  +S  S + G +P +++S +         D + SP
Sbjct: 832  KGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSP 891

Query: 1011 ----SRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREEEEL---LREQEKMREVE 1063
                +   + + A   RKAR  S      +  +S +E+ +   + L   +R         
Sbjct: 892  AGPAATPAQAQAASTPRKAR-ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTA 950

Query: 1064 QQRIRSTA----RKTRRDKEELRAQRRRERSKTPPSNLSPIEDASPTEELRQAAEMEELH 1119
              RI   A      + ++   +   +++E   T  S  +P         L+  A+     
Sbjct: 951  HPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEA 1010

Query: 1120 RSSCSEYSPSPSLDSEAEALDG----GPSRLYKSGSEYNLPTFMSLYSPTETPSGSSTTP 1175
            +   +   PS  +DS    L        S   K  ++   P    +   T+ P  S  + 
Sbjct: 1011 QPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSE 1070

Query: 1176 SSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHG--GPSQPTGPRGLGSFEYQDTT 1233
             S      +EE  E                 GA+  H   GP+ P+    L      +++
Sbjct: 1071 DSSDSSSGSEEDGE--------------GPQGAKSAHTLVGPT-PSRTETLVEETAAESS 1115

Query: 1234 DREYGQAAQPAAEG------TPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKE 1287
            + +    +Q    G      TPA+  A+     L +S S+       S  LA  +D   +
Sbjct: 1116 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSV-------SSTLAAKDDPDGK 1168

Query: 1288 KQFLNAESAYMDPMKQNGGPLTPGTSPTQLAAP 1320
            ++    ++A M   K  G     GT+P +   P
Sbjct: 1169 QEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKP 1201



 Score = 42.7 bits (99), Expect = 0.007
 Identities = 45/189 (23%), Positives = 68/189 (35%), Gaps = 22/189 (11%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK-- 3738
            P S    A    K  +P  P   + ++   +S     +SDS  GS +   GP   +S   
Sbjct: 1035 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1094

Query: 3739 ---AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALT 3795
                 P     L    AA   +      S+ + SG  +            GL P     +
Sbjct: 1095 LVGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP-----------GLTPANSQAS 1143

Query: 3796 QARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATG---PQPAGPPRAEQTNGSKGTAKAP 3852
            +A  +  S P+   +  A   P GK +  P  A G   P+  G   A  T   K  ++ P
Sbjct: 1144 KATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK--SRKP 1201

Query: 3853 QQGRA-PQA 3860
            ++G   PQA
Sbjct: 1202 KKGAGNPQA 1210



 Score = 35.0 bits (79), Expect = 1.5
 Identities = 40/171 (23%), Positives = 64/171 (37%), Gaps = 10/171 (5%)

Query: 3757 QQSQSPSSRQIPSGAASRQPQTQQQQQGL--GLQPPQQALTQARLQQQSQPTTRGSAPAA 3814
            +++++ + +   +G +   P T +    L  G  P + A   A     S+    GS PA 
Sbjct: 123  EKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAF 182

Query: 3815 SQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAG 3874
               A   +PG  +A     +    +  ++ +    KA ++    +A  AP  G  G  A 
Sbjct: 183  GAAA---KPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGAT 239

Query: 3875 ARPGGTPGA-----PAGQPGADGESVFSKILPGGAAEQAGKLTEAVSAFGK 3920
              P G  GA      AG+P  D ES   +         A K      A GK
Sbjct: 240  PAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGK 290



 Score = 34.3 bits (77), Expect = 2.5
 Identities = 126/620 (20%), Positives = 202/620 (32%), Gaps = 99/620 (15%)

Query: 1347 AKETQ--DPLKLHSSPASPSSASKEIGMPFSQGPGTPATTAVAPCPAGLPRGYMTPASPA 1404
            AK+T+  DP+    S      A  E      +   T ++   A  P+ +          A
Sbjct: 73   AKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKA 132

Query: 1405 GSERSPSPSSTAHSYGHSPTTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTP 1464
            G         T +S  H  T    G    +L    S   +A  +A    +S ++ EG  P
Sbjct: 133  GK--------TGNSMPHPAT----GKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180

Query: 1465 QPSRAYSYFASSSPPLSPSSPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMP---RSP 1521
                A      S+     SS   S +     +  +A+ +      + APA   P    +P
Sbjct: 181  AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATP 240

Query: 1522 GAPTPSPMVAQGTQTPHRPSTPRLVWQESS---QEAPFMVITLASDASSQTRMVHASAST 1578
              P  +  VA  T+            +ESS   +E P     L + AS +T  V A++  
Sbjct: 241  APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAAS-- 298

Query: 1579 SPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWGALPAE 1638
                +P +  P                 P PPG  G P V  A A         G    +
Sbjct: 299  ----APAKESPR------------KGAAPAPPGKTG-PAVAKAQA---------GKREED 332

Query: 1639 NISLCRISSVPGTSRVE-PGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEARKYG 1697
            + S    SS    S  E P    P      +R A  P               A E+ + G
Sbjct: 333  SQS----SSEESDSEEEAPAQAKPSGKAPQVRAASAP---------------AKESPRKG 373

Query: 1698 LALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQKQPVVYGDPYQS 1757
             A  P P R++      V     +E +  ++  + S   A +   A Q +P+      + 
Sbjct: 374  AA--PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKP 431

Query: 1758 RLDFGQG----GGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAK-FARYNLPNQVAPLA 1812
                G G    G  PV   +V     + Q   +         E+   +   +P  VAP  
Sbjct: 432  ASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 491

Query: 1813 RRDVLITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEGTA 1872
             + +          +  KP   P  G  P +A P  ++      A KP    +   E + 
Sbjct: 492  EKSL-------GNILQAKPTSSPAKG-PPQKAGPVAVQVK----AEKP----MDNSESSE 535

Query: 1873 GTVTTLLPEEPAGALDLTGMRPESQLACCDMVYKLPFGSSCTGTFHPAP-----SVPEKS 1927
             +  +   EE   A+     +P  ++         P  ++ T +   AP       P K+
Sbjct: 536  ESSDSADSEEAPAAMTAAQAKPALKI---PQTKACPKKTNTTASAKVAPVRVGTQAPRKA 592

Query: 1928 MADAAPPGQSSSPFYGPRDP 1947
                +P G S +   G + P
Sbjct: 593  GTATSPAGSSPAVAGGTQRP 612


>gi|207113160 Treacher Collins-Franceschetti syndrome 1 isoform d
            [Homo sapiens]
          Length = 1488

 Score = 72.8 bits (177), Expect = 6e-12
 Identities = 163/819 (19%), Positives = 281/819 (34%), Gaps = 108/819 (13%)

Query: 10   GAGDGPLPPGGAGPGPGPGPGPGAGK---------PPSAPAGGGQLPAAGA-----ARST 55
            G G GP+PPG  GP     P    GK           S+ +  G++P A A     +   
Sbjct: 518  GKGAGPVPPGKVGPAT---PSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGN 574

Query: 56   AVPPVPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQA-SATTPGHESPRETRA 114
             +   P   P  GP    G  + ++  ++P+ N  ++  +   A S   P   +  + + 
Sbjct: 575  ILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKP 634

Query: 115  QGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPY-SVPQIAPLPSSTLCPIC 173
                 Q    P++T    S      R  + +P +  T TSP  S P +A     T  P  
Sbjct: 635  ALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVA---GGTQRPAE 691

Query: 174  KTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQMQRALGMDMTTA 233
             +S    + S+    T            G        QVK     +  ++ +LG      
Sbjct: 692  DSSSSEESDSEEE-KTGLAVTVGQAKSVGKG-----LQVK---AASVPVKGSLGQGTAPV 742

Query: 234  PRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQA 293
               K+      P ++   +  ++     ++E         P   +    +  +   PA A
Sbjct: 743  LPGKT-----GPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797

Query: 294  AAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAP-----------AKSATAVPAGLGATEQT 342
             AP   G +S      T  + A+ R P+   P           A+   +VP+   A    
Sbjct: 798  RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857

Query: 343  QEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPLGS 402
             +  TG     G+S     S     + EA+T  Q  PS  T +I    A  +  P+    
Sbjct: 858  AQAQTGPEEDSGSSEEESDS-----EEEAETLAQVKPSGKTHQIRAALAPAKESPR---- 908

Query: 403  GPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKHGRAEHQAASKAA---------A 453
              G  P P  KT P A        G    +G ++       E  AA  +A          
Sbjct: 909  -KGAAPTPPGKTGPSAAQA-----GKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFV 962

Query: 454  KPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCL 513
             P   P   A  P      +   K+ A+ +T  +   +       +    ++  T+    
Sbjct: 963  DPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSE-------SEDEDVIPATQ---- 1011

Query: 514  NCQTKRLLEGSLGEPTPLP---PPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPA 570
             C T  +    +  PT  P   P  S      +   +  +   KQ+GP    Q S   PA
Sbjct: 1012 -CLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGP--ATQVSKKNPA 1068

Query: 571  KASPLSTKASPLPSKASPQAKPLRASEPSK-------TPSSVQEKKTRVPTKAEPMPKPP 623
                       L  KAS    P+  ++PS        T  +   + T V  K     + P
Sbjct: 1069 SLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKP 1128

Query: 624  --PETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVGKPYSQDASRSPQSLS 681
              PE       P+       +  ++   +   E P+G ++   +G   S+  +   ++ +
Sbjct: 1129 KLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAA 1188

Query: 682  DTGYSSDGISSSQSEITGVVQQEVEQLDS--AGVTGPHPPSPSEIHKVGS--------SM 731
            ++    D ++ SQS ++G +   +   +S  +  T     SPS    + +          
Sbjct: 1189 ESS-EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1247

Query: 732  RPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEA 770
            +P   A  L+P    K  +SGT  ++ ++P   +  P+A
Sbjct: 1248 KPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQA 1286



 Score = 70.1 bits (170), Expect = 4e-11
 Identities = 247/1199 (20%), Positives = 401/1199 (33%), Gaps = 196/1199 (16%)

Query: 670  SQDASRSPQSLSDTGYSSDGISSSQSEITGV---------VQQEVEQLDSAGVTGPHPPS 720
            S+ +    ++ ++T  ++  ++S+ S + G           + E E+    G + PHP +
Sbjct: 85   SESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPAT 144

Query: 721  PSEIHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITP---EAFDSDEEL 777
               +  + S   P   A+  A    +  L S T EE        +  P    A  +D   
Sbjct: 145  GKTVANLLSGKSPRKSAEPSA----NTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSS 200

Query: 778  EDILEE-DEDSAEWRRR-REQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQ---PPA 832
            ED     DE   E +   +  Q  A S     S  R         G ++P       PPA
Sbjct: 201  EDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPA 260

Query: 833  RAAELTDEDFMRRQILEMSAEEDNLEEDDTATSGRGLAK---------------HGTQKG 877
            + A+  +E+         S+EE +  E++     R   K                GT   
Sbjct: 261  KRAKKPEEE-------SESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGK 313

Query: 878  GPRPRPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGTLQGGLRRFKTIELN 937
            G  P P P +  A   + +                 S E T  +  L       KT ++ 
Sbjct: 314  GATPAP-PGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVG 372

Query: 938  STGSYGHELDL-GQGPDPSLDREPELEMESLTGSPEDRSRGEHSSTLPASTPSYT--SGT 994
            +  +   E    G  P P     P +         ED       S      P+    SG 
Sbjct: 373  AASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 995  SPTSLSSLEEDSDSSPSRRQRLEEAKQQRKARHRSHGPLLPTIEDSSEEEELREE-EELL 1053
            +P   ++      S+P++       K    A  R  GP    ++   +EE+ R   EE  
Sbjct: 433  APQVRAA------SAPAKES---PRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESD 483

Query: 1054 REQEKMREVEQQRIRSTARKTRRDKEELRAQRR--RERSKTPPSNLSPIEDASPTEELRQ 1111
             ++E +  +   +++   +  +             +     PP  + P   A+P+    Q
Sbjct: 484  SDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGP---ATPSA---Q 537

Query: 1112 AAEMEELHRSSCSEYSPSPSLDSEAEALDGGPSRLYKSGSEYNLPTFMSLYSPTETPSGS 1171
              + EE   SS  E S S          DG          E +L   +    PT      
Sbjct: 538  VGKWEEDSESSSEESSDSS---------DGEVPTAVAPAQEKSLGNILQA-KPT------ 581

Query: 1172 STTPSSGRPLKSAEEAYEEMMRKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQD 1231
             ++P+ G P K+   A +    K         +++ +      P+  T  +   + +   
Sbjct: 582  -SSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQ 640

Query: 1232 T------TDREYGQAAQPAAEGTPASLGAAVYEEILQTSQSIVRMRQASSRDLAFAE--D 1283
            T      T+        P   GT A   A        +S ++    Q  + D + +E  D
Sbjct: 641  TKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESD 700

Query: 1284 KKKEKQFL-----NAES--------AYMDPMK----QNGGPLTPG-TSPTQLAAPV---- 1321
             ++EK  L      A+S        A   P+K    Q   P+ PG T PT          
Sbjct: 701  SEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQE 760

Query: 1322 -SFSTPTSSDS-----SGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFS 1375
             S S+   SDS     S  +V   V+ TQ  AK      +  S+  + S+  K +     
Sbjct: 761  DSESSEEESDSEEAAASPAQVKTSVKKTQ--AKANPAAARAPSAKGTISAPGKVVTAAAQ 818

Query: 1376 QGPGTPA-----------TTAVAPCPAGLPRGYMTPASPAGSERSPSPSSTAHSYGHSPT 1424
                +P+           +T +A  PA +P      A+ A ++  P   S     G S  
Sbjct: 819  AKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDS-----GSSEE 873

Query: 1425 TANYGSQTEDLPQA-PSGLAAAGRAAREKPLSASDGEGGTPQPSRAYSYFASSSPPLSPS 1483
             ++   + E L Q  PSG     RAA   P   S  +G  P P       A+ +     S
Sbjct: 874  ESDSEEEAETLAQVKPSGKTHQIRAALA-PAKESPRKGAAPTPPGKTGPSAAQAGKQDDS 932

Query: 1484 SPSESPTFSPGKMGPRATAEFSTQTPSPAPASDMPRSPGAPTPSPMVAQGTQTPHR---- 1539
              S   + S G+  P A        P P    D  RSP  P  +P  AQ   TP +    
Sbjct: 933  GSSSEESDSDGE-APAAVTSAQVIKP-PLIFVDPNRSPAGPAATPAQAQAASTPRKARAS 990

Query: 1540 PSTPRLVWQESSQE---------------------------APFMVITLASDASSQTRMV 1572
             ST R    ES  E                           AP   +  AS +   +R+ 
Sbjct: 991  ESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRIS 1050

Query: 1573 HASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGW 1632
                   P    ++  P +   +Q     ++Q   E   PP     PS+G D  +     
Sbjct: 1051 DGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQ-PPVARTQPSSGVDSAV----- 1104

Query: 1633 GALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVK-PTPIILTDQGMDLTSLAV 1691
            G LPA +     + +  GT+++   P+ P     +++ A K P     ++   D +S + 
Sbjct: 1105 GTLPATSPQSTSVQA-KGTNKLRK-PKLP-----EVQQATKAPESSDDSEDSSDSSSGSE 1157

Query: 1692 E------ARKYGLALDPIPGRQSTAVQPLVI-----NLNAQEHTFLATATTVSITMASS 1739
            E        K    L P P R  T V+         ++ A   + L+   T  +T A+S
Sbjct: 1158 EDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANS 1216



 Score = 69.7 bits (169), Expect = 5e-11
 Identities = 112/506 (22%), Positives = 168/506 (33%), Gaps = 67/506 (13%)

Query: 3438 GGSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSL--SMAHSRVRP 3495
            G   ++   +A   +K    D     +  E E EA     KA P+ +S   S+  + +  
Sbjct: 60   GRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPS 119

Query: 3496 PMRSQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGPRAHAYKR 3555
             M+ +A  E       G   P     P  G T     S  S P             +   
Sbjct: 120  SMKEKAKAETEKAGKTGNSMPH----PATGKTVANLLSGKS-PRKSAEPSANTTLVSETE 174

Query: 3556 EEGYI----------LDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSS 3605
            EEG +          +  +    S SE      +ETD   KP   +  + +        S
Sbjct: 175  EEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKP-SVKPAQVKASSVSTKES 233

Query: 3606 SSQKRGPARHSYHDYDE--------PPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRH 3657
             ++K  PA     D           P +    P +E       S  E       R   + 
Sbjct: 234  PARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKA 293

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYP------SSAEYSQPSRA 3711
            + +    RAA   A+      A P + P  A A+  + + G P      SS E S     
Sbjct: 294  SEKILQVRAASAPAKGTPGKGATP-APPGKAGAVASQTKAGKPEEDSESSSEESSDSEEE 352

Query: 3712 SSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGA 3771
            + A      +K   + +  G A+  +K  P+       + AAP P     P+  +  +G 
Sbjct: 353  TPAAKALLQAKASGKTSQVGAASAPAKESPR-------KGAAPAPPGKTGPAVAKAQAGK 405

Query: 3772 ASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGP 3831
                 Q+  ++     + P QA    +  Q        SAPA   P     P P   TGP
Sbjct: 406  REEDSQSSSEESDSEEEAPAQAKPSGKAPQ----VRAASAPAKESPRKGAAPAPPRKTGP 461

Query: 3832 QPAGPPRAEQTNGSKGT----------------AKAPQQGRAPQAQPAP--GPGPAGVKA 3873
              A     +Q   S+ +                A+    G++PQ +PA   G GP G  A
Sbjct: 462  AAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA 521

Query: 3874 GARPGG-----TPGAPAGQPGADGES 3894
            G  P G     TP A  G+   D ES
Sbjct: 522  GPVPPGKVGPATPSAQVGKWEEDSES 547



 Score = 66.6 bits (161), Expect = 5e-10
 Identities = 226/1100 (20%), Positives = 372/1100 (33%), Gaps = 178/1100 (16%)

Query: 882  RPEPSQEPAALPKRRLPHNATTGYEELLPEGGSAEATDGSGT--------------LQGG 927
            R   ++E AAL  ++   +      E   E   AEA     T              L   
Sbjct: 61   RKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSS 120

Query: 928  LRRFKTIELNSTGSYGHEL----------DLGQGPDPSLDREPELEMESLTGSPEDRSR- 976
            ++     E    G  G+ +          +L  G  P    EP      ++ + E+ S  
Sbjct: 121  MKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVP 180

Query: 977  --GEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAK----QQRKARHRSH 1030
              G  +     S     S +  TS SS E D +  PS +    +A     ++  AR  + 
Sbjct: 181  AFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAP 240

Query: 1031 GP-----LLPTIEDSS--EEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRA 1083
             P     + P ++  +    +  ++ EE     E+  E E++    T  + +  ++ L+ 
Sbjct: 241  APGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQV 300

Query: 1084 QRRRERSKTPP---SNLSPIEDASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEAL- 1139
            +     +K  P   +  +P   A       +A + EE   SS  E S S      A+AL 
Sbjct: 301  RAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALL 360

Query: 1140 ----DGGPSRL-YKSGSEYNLPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEM--M 1192
                 G  S++   S      P   +  +P      +     +G+  + ++ + EE    
Sbjct: 361  QAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSE 420

Query: 1193 RKAELLQRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASL 1252
             +A    +  G+A   R     P++ +  +G           R+ G AA     G     
Sbjct: 421  EEAPAQAKPSGKAPQVRAA-SAPAKESPRKGAAP-----APPRKTGPAAAQVQVGKQEED 474

Query: 1253 GAAVYEEILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPG- 1311
              +  EE     +++  M  A  + L       K  Q   A +  M P+ +  GP+ PG 
Sbjct: 475  SRSSSEESDSDREALAAMNAAQVKPLG------KSPQVKPASTMGMGPLGKGAGPVPPGK 528

Query: 1312 TSPTQLAAPVS-------FSTPTSSDSSGGRVIPDVRVTQHF-------AKETQDPLKLH 1357
              P   +A V         S+  SSDSS G V   V   Q         AK T  P K  
Sbjct: 529  VGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGP 588

Query: 1358 SSPASPSSASKEIGMPFSQGPGTPATTAVAP---CPAGLPRGYMTPASPAGSERS-PSPS 1413
               A P +   +   P      +  ++  A     PA +      PA      ++ P  +
Sbjct: 589  PQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKT 648

Query: 1414 STAHSYGHSP----TTANYGSQTEDLPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSRA 1469
            +T  S   +P    T A   + T   P A S  A AG   R    S+S  E  + +    
Sbjct: 649  NTTASAKVAPVRVGTQAPRKAGTATSP-AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTG 707

Query: 1470 YSYFA-------------SSSPPLSPSSPSESPTFSPGKMGPRAT---AEFSTQTPSPAP 1513
             +                ++S P+  S    +    PGK GP  T   AE    + S   
Sbjct: 708  LAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEE 767

Query: 1514 ASDMPRSPGAPTPSPMVAQGTQTPHRPSTPRLVWQESSQEAPFMVITLASDASSQTRMVH 1573
             SD   +  +P       + TQ    P+  R    + +  AP  V+T A+ A  +     
Sbjct: 768  ESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQR----- 822

Query: 1574 ASASTSPLCSPTETQPTTHGYSQTTPPSVSQLPPEPPGPPGFPRVPSAGADGPLALYGWG 1633
                     SP++ +P       +T  +         GP   P V  A A    A  G  
Sbjct: 823  ---------SPSKVKPPVRNPQNSTVLA--------RGPASVPSVGKAVATAAQAQTG-- 863

Query: 1634 ALPAENISLCRISSVPGTSRVEPGPRTPGTAVVDLRTAVKPTPIILTDQGMDLTSLAVEA 1693
              P E+          G+S  E         +  ++ + K      T Q     + A E+
Sbjct: 864  --PEED---------SGSSEEESDSEEEAETLAQVKPSGK------THQIRAALAPAKES 906

Query: 1694 RKYGLALDPIPGRQSTAVQPLVINLNAQEHTFLATATTVSITMASSVFMAQQ--KQPVVY 1751
             + G A  P PG+      P       Q+ +  ++  + S   A +   + Q  K P+++
Sbjct: 907  PRKGAAPTP-PGKTG----PSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIF 961

Query: 1752 GDPYQSRLDFGQGGGSPVCLAQVKQVEQAVQTAPYRSGPRGRPREAKFARYNLPNQVAPL 1811
             DP +          SP   A      QA  T          PR+A+ +     +  +  
Sbjct: 962  VDPNR----------SPAGPAATPAQAQAAST----------PRKARASESTARSSSSES 1001

Query: 1812 ARRDVL-ITQMGTAQSIGLKPGPVPEPGAEPHRATPAELRSHALPGARKPHTVVVQMGEG 1870
               DV+  TQ  T    G++   V  P A P  A  A +       +    +  +  G+ 
Sbjct: 1002 EDEDVIPATQCLTP---GIRTNVVTMPTAHPRIAPKASMAG----ASSSKESSRISDGKK 1054

Query: 1871 TAGTVTTLLPEEPAGALDLT 1890
              G  T +  + PA +L LT
Sbjct: 1055 QEGPATQVSKKNPA-SLPLT 1073



 Score = 65.1 bits (157), Expect = 1e-09
 Identities = 195/940 (20%), Positives = 308/940 (32%), Gaps = 168/940 (17%)

Query: 3036 PATAAAPATP--SGPTAFQQPRFQPPAPQYSAGS-GGPTQNGFPAHQA---------PTY 3083
            P   A PA P  +G  A Q    +P     S+      ++   PA +A          + 
Sbjct: 311  PGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQ 370

Query: 3084 PGPSTYPAPAFPPGASYPAEPGLPNQQAFRPTGHYAGQTPMPTTQSTLFPVPADSRAPLQ 3143
             G ++ PA   P   + PA PG         TG                  PA ++A   
Sbjct: 371  VGAASAPAKESPRKGAAPAPPG--------KTG------------------PAVAKAQAG 404

Query: 3144 KPRQTSLADLEQKVPTNYEVIASPVVPMSSAPSETSYSGPAVSSGYEQGKVPEVPRAGDR 3203
            K  + S +  E+    + E   +   P   AP   + S PA  S   +G  P  PR    
Sbjct: 405  KREEDSQSSSEES--DSEEEAPAQAKPSGKAPQVRAASAPAKESP-RKGAAPAPPRKTGP 461

Query: 3204 GSVSQSPAPTYPSDSHYTSLEQNVPRNYVMIDDISELTKDSTSTAPDSQRLEPLGPGSSG 3263
             + +Q        DS  +S E +  R  +   + +++     S  P  +    +G G  G
Sbjct: 462  AA-AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKS--PQVKPASTMGMGPLG 518

Query: 3264 RPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHYYGDS 3323
            + G  P  PG +   T      + EE+SE  S +         S  S+G   +      +
Sbjct: 519  K-GAGPVPPGKVGPATPSAQVGKWEEDSESSSEES--------SDSSDGEVPTA--VAPA 567

Query: 3324 DYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQKISKFSPIEEAKDVES 3383
              +    + +  P     K P +   P A+  K  K        +       E +   +S
Sbjct: 568  QEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSE-------ESSDSADS 620

Query: 3384 DLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYY------------GMSSRDAV 3431
            + A   P A++++      K         K N     K              G ++  A 
Sbjct: 621  EEA---PAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAG 677

Query: 3432 EDDRIYGGSSRSRAPSAYSGEKLSSHDFSGW----------GKGYEREREAVERLQKAG- 3480
                + GG+ R    S+ S E  S  + +G           GKG + +  +V      G 
Sbjct: 678  SSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQ 737

Query: 3481 ------PKPSSLSMAHSRVRPPMRSQASEEESP-----VSPL------------GRPRPA 3517
                  P  +  ++   +      S++SEEES       SP               P  A
Sbjct: 738  GTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAA 797

Query: 3518 GGPLPPGGDTCP-------QFCSSHSMPDVQEHVKDGPRAHAYKREEGYILDDSHCVVSD 3570
              P   G  + P             S   V+  V++   +    R    +      V + 
Sbjct: 798  RAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 857

Query: 3571 SEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARHSYHDYDEPPEEGLWP 3630
            ++A    +E++   ++  D+  +        A    S K    R +     E P +G  P
Sbjct: 858  AQAQTGPEEDSGSSEEESDSEEEAETL----AQVKPSGKTHQIRAALAPAKESPRKGAAP 913

Query: 3631 HDEG--GPGRHASAKEHRHGDHGRHSGRHTGEEPGR----RAAKPHAR--DLGRHEARPH 3682
               G  GP    + K+   G     S    GE P      +  KP     D  R  A P 
Sbjct: 914  TPPGKTGPSAAQAGKQDDSGSSSEESDSD-GEAPAAVTSAQVIKPPLIFVDPNRSPAGPA 972

Query: 3683 SQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQ 3742
            + P+ A A         P  A  S+ +  SS+     +    + Q  +          P 
Sbjct: 973  ATPAQAQAAST------PRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPT 1026

Query: 3743 AQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQARLQQQ 3802
            A P++  + +  G   S S  S +I  G     P TQ  ++     P    LTQA L+  
Sbjct: 1027 AHPRIAPKASMAGA--SSSKESSRISDGKKQEGPATQVSKKN----PASLPLTQAALKVL 1080

Query: 3803 SQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA--PQQGRAPQA 3860
            +Q  +    P A     +P  G  +A G  PA  P++     +KGT K   P+     QA
Sbjct: 1081 AQKASEAQPPVART---QPSSGVDSAVGTLPATSPQSTSVQ-AKGTNKLRKPKLPEVQQA 1136

Query: 3861 QPAP-------------------GPGPAGVKAGARPGGTP 3881
              AP                   G GP G K+    G TP
Sbjct: 1137 TKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTP 1176



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 262/1294 (20%), Positives = 426/1294 (32%), Gaps = 250/1294 (19%)

Query: 236  SKSQQQLHSPALSPAHSPAKQPLGKPDQERS-----------RGPGGPQPGSRQAETARA 284
            S+++++   PA   A  P     G+ D                G    +P   +A +   
Sbjct: 171  SETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVST 230

Query: 285  TSVPGPAQAAAPPEVGRVSPQ-------------PPQPTKPSTAEPRPPAGEAPAKSATA 331
               P    A AP +VG V+PQ              P+    S+ E      EAPA + + 
Sbjct: 231  KESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 332  VPAG-----LGATEQTQEGLTGKLFGLGASLL------TQASTLMSVQPEADTQGQPAPS 380
            V A      + A     +G  GK    GA+          AS   + +PE D++     S
Sbjct: 291  VKASEKILQVRAASAPAKGTPGK----GATPAPPGKAGAVASQTKAGKPEEDSESSSEES 346

Query: 381  ----KGTPKIVFNDASKEAG-PKPLGSGPGP---GPAPGAKTEPGARMGPGSGPGALPK- 431
                + TP       +K +G    +G+   P    P  GA   P  + GP        K 
Sbjct: 347  SDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKR 406

Query: 432  -TGGTTSPKHGRAEHQAASKAAAKPKTMPKERAICPLCQAELNVGSKSPANYNTCTTCRL 490
                 +S +   +E +A ++A    K      A  P  ++     + +P         ++
Sbjct: 407  EEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQV 466

Query: 491  QVCNLCGFNPTPHLVEKTEWLCLNCQTKRLLEGSLGEPTPLPPPTSQQ-PPVGAPHRASG 549
            Q             V K E       ++   E S  +   L    + Q  P+G   ++  
Sbjct: 467  Q-------------VGKQEE-----DSRSSSEESDSDREALAAMNAAQVKPLG---KSPQ 505

Query: 550  TSPLKQKGPQGLGQPSGPL-PAKASPLSTKASPLPSKASPQAKPLRASEPSKTPS--SVQ 606
              P    G   LG+ +GP+ P K  P           A+P A+  +  E S++ S  S  
Sbjct: 506  VKPASTMGMGPLGKGAGPVPPGKVGP-----------ATPSAQVGKWEEDSESSSEESSD 554

Query: 607  EKKTRVPTKAEPMPKPPPETTPTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAEDLVG 666
                 VPT               PA  K    + +A+P +   K  P+  K G     V 
Sbjct: 555  SSDGEVPTAV------------APAQEKSLGNILQAKPTSSPAKGPPQ--KAGPVAVQVK 600

Query: 667  KPYSQDASRSPQSLSDTGYSSD---GISSSQSEITGVVQQEVEQLDSAGVTGPHPPSPSE 723
                 D S S +  SD+  S +    ++++Q++    + Q          T     +P  
Sbjct: 601  AEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVR 660

Query: 724  IHKVGSSMRPLLQAQGLAPSERSKPLSSGTGEEQKQRPHSLSITPEAFDSDEELEDILEE 783
            +     +  P       +P+  S  ++ GT     QRP   S + E  DS+EE   +   
Sbjct: 661  V----GTQAPRKAGTATSPAGSSPAVAGGT-----QRPAEDSSSSEESDSEEEKTGLAVT 711

Query: 784  DEDSAEWRRRREQQDTAESSDDFGSQLRHDYVEDSSEGGLSPLPPQPPARAAELTDEDFM 843
               +               S   G Q++   V      G    P  P      +T     
Sbjct: 712  VGQA--------------KSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAE 757

Query: 844  RRQILEMSAEEDNLEEDDTATSGRGLAKHGTQKGGPRPRPEPSQEPAALPKRRLPHNATT 903
            +++  E S EE + EE   A +     K   +K   +  P  ++ P+A      P    T
Sbjct: 758  KQEDSESSEEESDSEE---AAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVT 814

Query: 904  GYEELLPEGGSAEATDGSGTLQGGLRRFKTIELNSTGSYGHELDLGQGPDPSLDREPELE 963
                      +A+A   S +      + K    N   S    L  G    PS+ +     
Sbjct: 815  ---------AAAQAKQRSPS------KVKPPVRNPQNS--TVLARGPASVPSVGKAVATA 857

Query: 964  MESLTGSPEDRSRGEHSSTLPASTPSYTSGTSPTSLSSLEEDSDSSPSRRQRLEEAKQQR 1023
             ++ TG  ED                  SG+S       EE+SDS     + L + K   
Sbjct: 858  AQAQTGPEED------------------SGSS-------EEESDSE-EEAETLAQVKPSG 891

Query: 1024 KARHRSHGPLLPTIEDSSEEEELREEEELLREQEKMREVEQQRIRSTARKTRRDKEELRA 1083
            K  H+    L P  E  S  +               +  +Q    S++ ++  D E   A
Sbjct: 892  KT-HQIRAALAPAKE--SPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAA 948

Query: 1084 QRRRERSKTPPSNLSPIED-ASPTEELRQAAEMEELHRSSCSEYSPSPSLDSEAEALDGG 1142
                +  K P   + P    A P     QA       ++  SE S + S  SE+E  D  
Sbjct: 949  VTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASE-STARSSSSESEDEDVI 1007

Query: 1143 P-SRLYKSGSEYN---LPTFMSLYSPTETPSGSSTTPSSGRPLKSAEEAYEEMMRKAELL 1198
            P ++    G   N   +PT     +P  + +G+S++  S R     ++            
Sbjct: 1008 PATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQE----------- 1056

Query: 1199 QRQQGQAAGARGPHGGPSQPTGPRGLGSFEYQDTTDREYGQAAQPAAEGTPASLGAAVYE 1258
                           GP+     +   S      T       AQ A+E  P         
Sbjct: 1057 ---------------GPATQVSKKNPASL---PLTQAALKVLAQKASEAQP--------- 1089

Query: 1259 EILQTSQSIVRMRQASSRDLAFAEDKKKEKQFLNAESAYMDPMKQNGGPLTPGTSPTQLA 1318
                    + R + +S  D A         Q  + ++   + +++   P  P       A
Sbjct: 1090 -------PVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRK---PKLPEVQQATKA 1139

Query: 1319 APVSFSTPTSSDSSGGRVIPDVRVTQHFAKETQDPLKLHSSPASPSSASKEIGMPFSQGP 1378
               S  +  SSDSS G        ++   +  Q     H+   +PS     +    ++  
Sbjct: 1140 PESSDDSEDSSDSSSG--------SEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAE-- 1189

Query: 1379 GTPATTAVAPCPAGLPRGYMTPA-SPAGSERSPSPSSTAHSYGHSPTTA---NYGSQTED 1434
             +     VAP  + L  GYMTP  +PA S+ S +      S   S T A   +   + E 
Sbjct: 1190 -SSEDDVVAPSQS-LLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEA 1247

Query: 1435 LPQAPSGLAAAGRAAREKPLSASDGEGGTPQPSR 1468
             PQ  +G+ +     +E         G TPQ SR
Sbjct: 1248 KPQQAAGMLSPKTGGKEA------ASGTTPQKSR 1275



 Score = 57.0 bits (136), Expect = 4e-07
 Identities = 72/319 (22%), Positives = 110/319 (34%), Gaps = 44/319 (13%)

Query: 3622 EPPEEGLWPHDEGG--PGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEA 3679
            E  EEG  P       PG  ++ +     +    S   T  E G+ + KP          
Sbjct: 172  ETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVE-GKPSVKPAQVKASSVST 230

Query: 3680 RPHSQPSSAPAMPKKGQP-------GYPSSAEYSQPSRASSAYHHASDSKK----GSR-Q 3727
            +      +APA  K G           P +    +P   S +    S+S++    G+R Q
Sbjct: 231  KESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQ 290

Query: 3728 AHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGL 3787
              +    LQ +A         G+ A P P       + Q  +G      ++  ++     
Sbjct: 291  VKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSE 350

Query: 3788 Q--PPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPPRAEQTNGS 3845
            +  P  +AL QA+   ++      SAPA   P     P P   TGP  A     ++   S
Sbjct: 351  EETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDS 410

Query: 3846 KGT-----------AKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGES 3894
            + +           A+A   G+APQ + A  P     + GA P     AP  + G     
Sbjct: 411  QSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAP-----APPRKTG----- 460

Query: 3895 VFSKILPGGAAEQAGKLTE 3913
                  P  A  Q GK  E
Sbjct: 461  ------PAAAQVQVGKQEE 473



 Score = 55.8 bits (133), Expect = 8e-07
 Identities = 139/696 (19%), Positives = 211/696 (30%), Gaps = 122/696 (17%)

Query: 14  GPLPPGGAGPGP---GPGPGPGAGKPPSAPAGGGQLPAAGA------ARSTAVPPVPGPG 64
           G LPP      P         G+     APAG      A        A S      PG G
Sbjct: 255 GALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKG 314

Query: 65  PGPGPGPGPGSTSRRLDPKEP-----------------------LGNQRAASPTPKQASA 101
             P P    G+ + +    +P                       L   +A+  T +  +A
Sbjct: 315 ATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAA 374

Query: 102 TTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRSGRSPSVSPDRGSTPTSPYSVPQI 161
           + P  ESPR+  A  P G+   GP        + +   +S S   D      +       
Sbjct: 375 SAPAKESPRKGAAPAPPGK--TGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGK 432

Query: 162 APLPSSTLCPICKTSDLTSTPSQPNFNTCTQCHNKVCNQCGFNPNPHLTQVKEWLCLNCQ 221
           AP   +   P  ++    + P+ P                     P   QV+        
Sbjct: 433 APQVRAASAPAKESPRKGAAPAPPR-----------------KTGPAAAQVQ-------- 467

Query: 222 MQRALGMDMTTAPRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAET 281
               +G     +  S  +      AL+  ++   +PLGK  Q +     G  P  + A  
Sbjct: 468 ----VGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGA-- 521

Query: 282 ARATSVPGPAQAAAPPEVGRVSPQPPQPTKPSTAEPRPPAGEAPAKSATA-VPAGLGATE 340
                  GP     PP  G+V P  P        E    + E  + S+   VP  +   +
Sbjct: 522 -------GP----VPP--GKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQ 568

Query: 341 QTQEGLTGKLFGLGASLLTQASTLMSVQPEADTQGQPAPSKGTPKIVFNDASKEAGPKPL 400
           +   G          ++L    T    +      G  A      K + N  S E      
Sbjct: 569 EKSLG----------NILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSA 618

Query: 401 GSGPGPGPAPGAKTEPGARMGPGSGPGALPKTGGTTSPKH---GRAEHQAASKAAAKPKT 457
            S   P     A+ +P  ++       A PK   TT+       R   QA  KA      
Sbjct: 619 DSEEAPAAMTAAQAKPALKIPQTK---ACPKKTNTTASAKVAPVRVGTQAPRKAGTATSP 675

Query: 458 MPKERAICPLCQAELNVGSKSPANYNTCTTCRLQVCNLCGFNPTPHLVEKTEWLCLNCQT 517
                A+    Q      S S  + +      L V            V + + +    Q 
Sbjct: 676 AGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAV-----------TVGQAKSVGKGLQV 724

Query: 518 KRL---LEGSLGEPTPLPPPTSQQPPVGAPHRASGTSPLKQKGPQGLGQPSGPLPAKASP 574
           K     ++GSLG+ T    P    P V      +     KQ+  +   + S    A ASP
Sbjct: 725 KAASVPVKGSLGQGTAPVLPGKTGPTV------TQVKAEKQEDSESSEEESDSEEAAASP 778

Query: 575 LSTKASPLPSKASPQAKPLRA-------SEPSKTPSSVQEKKTRVPTKAEPMPKPPPETT 627
              K S   ++A       RA       S P K  ++  + K R P+K +P  + P  +T
Sbjct: 779 AQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNST 838

Query: 628 PTPATPKVKSGVRRAEPATPVVKAVPEAPKGGEAED 663
                P     V +A       +  PE   G   E+
Sbjct: 839 VLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEE 874



 Score = 43.1 bits (100), Expect = 0.005
 Identities = 45/188 (23%), Positives = 68/188 (36%), Gaps = 21/188 (11%)

Query: 3681 PHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSK-- 3738
            P S    A    K  +P  P   + ++   +S     +SDS  GS +   GP   +S   
Sbjct: 1112 PQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHT 1171

Query: 3739 --AEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQ 3796
                P     L    AA   +      S+ + SG  +            GL P     ++
Sbjct: 1172 LGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTP-----------GLTPANSQASK 1220

Query: 3797 ARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATG---PQPAGPPRAEQTNGSKGTAKAPQ 3853
            A  +  S P+   +  A   P GK +  P  A G   P+  G   A  T   K  ++ P+
Sbjct: 1221 ATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQK--SRKPK 1278

Query: 3854 QGRA-PQA 3860
            +G   PQA
Sbjct: 1279 KGAGNPQA 1286



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 65/264 (24%), Positives = 96/264 (36%), Gaps = 50/264 (18%)

Query: 3658 TGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHH 3717
            +G+ P R++A+P A      E     +  S PA     +PG  S+ +    S  +S+   
Sbjct: 153  SGKSP-RKSAEPSANTTLVSETE---EEGSVPAFGAAAKPGMVSAGQADSSSEDTSS--- 205

Query: 3718 ASDSKKGSRQAHSGPAALQSKAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQ 3777
            +SD      +    PA  Q KA   +  +   R+AAP P                 +   
Sbjct: 206  SSDETDVEGKPSVKPA--QVKASSVSTKESPARKAAPAP----------------GKVGD 247

Query: 3778 TQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGPP 3837
               Q +G  L P ++A    + +++S+ +  GS      PAG         T  Q     
Sbjct: 248  VTPQVKGGALPPAKRA---KKPEEESESSEEGSESEEEAPAG---------TRSQVKASE 295

Query: 3838 RAEQTNGSKGTAKA-PQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQPGADGESVF 3896
            +  Q   +   AK  P +G    A PAP PG AG  A           AG+P  D ES  
Sbjct: 296  KILQVRAASAPAKGTPGKG----ATPAP-PGKAGAVASQ-------TKAGKPEEDSESSS 343

Query: 3897 SKILPGGAAEQAGKLTEAVSAFGK 3920
             +         A K      A GK
Sbjct: 344  EESSDSEEETPAAKALLQAKASGK 367



 Score = 39.7 bits (91), Expect = 0.060
 Identities = 128/617 (20%), Positives = 196/617 (31%), Gaps = 119/617 (19%)

Query: 3260 GSSGRPGKEPGEPGVLDGPTLPCCYARGEEESEEDSYDPRGKGGHLRSMESNGRPASTHY 3319
            G S R   EP     L   T        EEE    ++    K G + + +++     T  
Sbjct: 154  GKSPRKSAEPSANTTLVSET--------EEEGSVPAFGAAAKPGMVSAGQADSSSEDTSS 205

Query: 3320 YGDSDYRHGARVEKYGPGPMGPKHPSKSLAPAAISSKRSKHRKQGMEQ-KISKFSPIEEA 3378
              D     G            P      +  +++S+K S  RK      K+   +P  + 
Sbjct: 206  SSDETDVEGK-----------PSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKG 254

Query: 3379 KDVESDLASYPPPAVSSSLVSRGRKFQDEITYGLKKNVYEQQKYYGMSSRDAVEDDRIYG 3438
              +     +  P   S S    G + ++E   G +  V   +K   +  R A    +   
Sbjct: 255  GALPPAKRAKKPEEESESS-EEGSESEEEAPAGTRSQVKASEKI--LQVRAASAPAKGTP 311

Query: 3439 GSSRSRAPSAYSGEKLSSHDFSGWGKGYEREREAVERLQKAGPKPSSLSMAHSRVRPPMR 3498
            G   + AP   +G   S        +  E   E     ++  P   +L  A +  +    
Sbjct: 312  GKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKT--- 368

Query: 3499 SQASEEESPVSPLGRPRPAGGPLPPGGDTCPQFCSSHSMPDVQEHVKDGP---RAHAYKR 3555
            SQ     +P      PR    P PPG                    K GP   +A A KR
Sbjct: 369  SQVGAASAPAKE--SPRKGAAPAPPG--------------------KTGPAVAKAQAGKR 406

Query: 3556 EEGYILDDSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARH 3615
            EE      S    SDSE      EE     KP   ++ + R     A  S  +   PA  
Sbjct: 407  EED---SQSSSEESDSE------EEAPAQAKP-SGKAPQVRAASAPAKESPRKGAAPA-- 454

Query: 3616 SYHDYDEPPEEGLWPHDEGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHA--RD 3673
                          P  + GP   A  +  +  +  R S   +  +    AA   A  + 
Sbjct: 455  --------------PPRKTGPAA-AQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKP 499

Query: 3674 LGRHEARPHSQPSSA-----------PAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSK 3722
            LG+    P  +P+S            P  P K  P  PS+        + S+   +SDS 
Sbjct: 500  LGKS---PQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSS 556

Query: 3723 KGSRQAHSGPAALQS-----KAEPQAQPQLQGRQAAPGPQQSQSPSSRQIPS-GAASRQP 3776
             G       PA  +S     +A+P + P       A GP Q   P + Q+ +        
Sbjct: 557  DGEVPTAVAPAQEKSLGNILQAKPTSSP-------AKGPPQKAGPVAVQVKAEKPMDNSE 609

Query: 3777 QTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTATGPQPAGP 3836
             +++       +    A+T A+           + PA   P  K  P  +  T      P
Sbjct: 610  SSEESSDSADSEEAPAAMTAAQ-----------AKPALKIPQTKACPKKTNTTASAKVAP 658

Query: 3837 PR-AEQTNGSKGTAKAP 3852
             R   Q     GTA +P
Sbjct: 659  VRVGTQAPRKAGTATSP 675


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.308    0.127    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 208,951,501
Number of Sequences: 37866
Number of extensions: 14675343
Number of successful extensions: 216595
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1058
Number of HSP's successfully gapped in prelim test: 3870
Number of HSP's that attempted gapping in prelim test: 64931
Number of HSP's gapped (non-prelim): 101149
length of query: 3926
length of database: 18,247,518
effective HSP length: 122
effective length of query: 3804
effective length of database: 13,627,866
effective search space: 51840402264
effective search space used: 51840402264
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 72 (32.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.

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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.