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Search of human proteins with 91199543
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
(1858 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 3852 0.0
gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo s... 3852 0.0
gi|122937492 SET domain containing 5 [Homo sapiens] 585 e-166
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 96 4e-19
gi|55750053 atrophin-1 [Homo sapiens] 94 9e-19
gi|55750041 atrophin-1 [Homo sapiens] 94 9e-19
gi|160707881 formin 2 [Homo sapiens] 94 2e-18
gi|112382224 atrophin-1 like protein isoform a [Homo sapiens] 93 2e-18
gi|112382216 atrophin-1 like protein isoform a [Homo sapiens] 93 2e-18
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 92 4e-18
gi|42544125 splicing factor 1 isoform 2 [Homo sapiens] 91 1e-17
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 91 1e-17
gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [... 90 2e-17
gi|47132519 Ras association and pleckstrin homology domains 1 is... 87 2e-16
gi|42544130 splicing factor 1 isoform 1 [Homo sapiens] 87 2e-16
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 86 4e-16
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 84 1e-15
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 83 2e-15
gi|110349788 absent, small, or homeotic 1-like [Homo sapiens] 82 5e-15
gi|150417989 cyclin K isoform 1 [Homo sapiens] 81 1e-14
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 80 2e-14
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming... 80 2e-14
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 79 3e-14
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 79 5e-14
gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens] 78 9e-14
gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens] 77 1e-13
gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens] 77 2e-13
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 76 3e-13
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 76 3e-13
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 75 5e-13
>gi|91199543 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 3852 bits (9989), Expect = 0.0
Identities = 1858/1858 (100%), Positives = 1858/1858 (100%)
Query: 1 MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60
MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP
Sbjct: 1 MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60
Query: 61 YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120
YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR
Sbjct: 61 YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120
Query: 121 CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180
CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK
Sbjct: 121 CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180
Query: 181 RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK 240
RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK
Sbjct: 181 RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK 240
Query: 241 CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA 300
CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA
Sbjct: 241 CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA 300
Query: 301 QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG 360
QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG
Sbjct: 301 QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG 360
Query: 361 KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE 420
KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE
Sbjct: 361 KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE 420
Query: 421 IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN 480
IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN
Sbjct: 421 IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN 480
Query: 481 INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN 540
INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN
Sbjct: 481 INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN 540
Query: 541 QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ 600
QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ
Sbjct: 541 QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ 600
Query: 601 ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH 660
ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH
Sbjct: 601 ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH 660
Query: 661 IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL 720
IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL
Sbjct: 661 IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL 720
Query: 721 NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS 780
NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS
Sbjct: 721 NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS 780
Query: 781 PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ 840
PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ
Sbjct: 781 PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ 840
Query: 841 ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH 900
ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH
Sbjct: 841 ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH 900
Query: 901 TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI 960
TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI
Sbjct: 901 TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI 960
Query: 961 KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV 1020
KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV
Sbjct: 961 KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV 1020
Query: 1021 SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV 1080
SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV
Sbjct: 1021 SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV 1080
Query: 1081 NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN 1140
NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN
Sbjct: 1081 NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN 1140
Query: 1141 LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA 1200
LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA
Sbjct: 1141 LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA 1200
Query: 1201 SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ 1260
SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ
Sbjct: 1201 SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ 1260
Query: 1261 VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE 1320
VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE
Sbjct: 1261 VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE 1320
Query: 1321 LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW 1380
LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW
Sbjct: 1321 LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW 1380
Query: 1381 DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH 1440
DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH
Sbjct: 1381 DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH 1440
Query: 1441 CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY 1500
CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY
Sbjct: 1441 CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY 1500
Query: 1501 PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ 1560
PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ
Sbjct: 1501 PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 1561 QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ 1620
QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ
Sbjct: 1561 QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ 1620
Query: 1621 TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680
TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP
Sbjct: 1621 TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680
Query: 1681 PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH 1740
PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH
Sbjct: 1681 PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH 1740
Query: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP 1800
HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP
Sbjct: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP 1800
Query: 1801 NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH 1858
NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH
Sbjct: 1801 NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH 1858
>gi|33636768 myeloid/lymphoid or mixed-lineage leukemia 5 [Homo
sapiens]
Length = 1858
Score = 3852 bits (9989), Expect = 0.0
Identities = 1858/1858 (100%), Positives = 1858/1858 (100%)
Query: 1 MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60
MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP
Sbjct: 1 MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60
Query: 61 YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120
YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR
Sbjct: 61 YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120
Query: 121 CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180
CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK
Sbjct: 121 CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180
Query: 181 RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK 240
RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK
Sbjct: 181 RENMSDGDTSATESGDEVPVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQHISK 240
Query: 241 CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA 300
CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA
Sbjct: 241 CKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQREA 300
Query: 301 QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG 360
QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG
Sbjct: 301 QRIALRLGNGNDKKEMNKSDLNTNNLLFKPPVESHIQKNKKILKSAKDLPPDALIIEYRG 360
Query: 361 KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE 420
KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE
Sbjct: 361 KFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFIRRSCTPNAEVRHE 420
Query: 421 IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN 480
IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN
Sbjct: 421 IQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPECPVLKRSSESMEN 480
Query: 481 INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN 540
INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN
Sbjct: 481 INSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKSPETKQRKLSPLRLSVSNN 540
Query: 541 QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ 600
QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ
Sbjct: 541 QEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRREQ 600
Query: 601 ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH 660
ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH
Sbjct: 601 ALERISTAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTH 660
Query: 661 IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL 720
IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL
Sbjct: 661 IGQQRRRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPAL 720
Query: 721 NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS 780
NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS
Sbjct: 721 NKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPGLTYS 780
Query: 781 PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ 840
PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ
Sbjct: 781 PHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFNSPCQ 840
Query: 841 ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH 900
ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH
Sbjct: 841 ERSRSPAVNGENKSPLLLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPYATPTH 900
Query: 901 TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI 960
TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI
Sbjct: 901 TDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPESSPEI 960
Query: 961 KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV 1020
KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV
Sbjct: 961 KRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPGEKEPV 1020
Query: 1021 SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV 1080
SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV
Sbjct: 1021 SDLQLGLDAVEPTALHKTLETPAHDRAEPNSQLDSTHSGRGTMYSSWVKSPDRTGVNFSV 1080
Query: 1081 NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN 1140
NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN
Sbjct: 1081 NSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVFCTSEDGLVSGFGRTVNDN 1140
Query: 1141 LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA 1200
LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA
Sbjct: 1141 LIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCA 1200
Query: 1201 SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ 1260
SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ
Sbjct: 1201 SSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQ 1260
Query: 1261 VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE 1320
VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE
Sbjct: 1261 VRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSE 1320
Query: 1321 LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW 1380
LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW
Sbjct: 1321 LMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQW 1380
Query: 1381 DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH 1440
DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH
Sbjct: 1381 DSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLH 1440
Query: 1441 CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY 1500
CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY
Sbjct: 1441 CPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY 1500
Query: 1501 PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ 1560
PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ
Sbjct: 1501 PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ 1560
Query: 1561 QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ 1620
QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ
Sbjct: 1561 QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQ 1620
Query: 1621 TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680
TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP
Sbjct: 1621 TAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP 1680
Query: 1681 PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH 1740
PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH
Sbjct: 1681 PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALH 1740
Query: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP 1800
HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP
Sbjct: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP 1800
Query: 1801 NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH 1858
NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH
Sbjct: 1801 NSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGWH 1858
>gi|122937492 SET domain containing 5 [Homo sapiens]
Length = 1442
Score = 585 bits (1508), Expect = e-166
Identities = 518/1665 (31%), Positives = 750/1665 (45%), Gaps = 347/1665 (20%)
Query: 1 MSIVIPLGVDTAETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLP 60
MSI IPLGV T++TSY +MAAGS+PESVEASP V EKS H T+ H GLP
Sbjct: 1 MSIAIPLGVTTSDTSYSDMAAGSDPESVEASPAVNEKSVYSTHNYGTTQRHGCR---GLP 57
Query: 61 YADHNYGARPPPTPPASPPPSVLISKNEVGIFTTPNFDETSSATTISTSEDGSYGTDVTR 120
YA +I ++++ +P + S + +G T T
Sbjct: 58 YA-------------------TIIPRSDLNGLPSPVEERCGD----SPNSEGE--TVPTW 92
Query: 121 CICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYLCERCQPRNLDKERAVLLQRRK 180
C CG + D G+++ CDKC R + + + + L RRK
Sbjct: 93 CPCGLSQD-GFLLNCDKC---------------------------RGMSRGKVIRLHRRK 124
Query: 181 RENMSDGDTSATESGDEV---PVELYTAFQHTPTSITLTASRVSKVNDKRRKKSGEKEQH 237
++N+S GD+SATES DE LYTA QHTPTSITLT V + K+RKKS EK +
Sbjct: 125 QDNISGGDSSATESWDEELSPSTVLYTATQHTPTSITLT---VRRTKPKKRKKSPEKGRA 181
Query: 238 ISKCKKAFREGSRKSSRVKGSAPEIDPSSDGSNFGWETKIKAWMDRYEEANNNQYSEGVQ 297
K KK +K S E + + GWE +I+ W D+YEEA NQYS VQ
Sbjct: 182 APKTKK-----------IKNSPSEAQNLDENTTEGWENRIRLWTDQYEEAFTNQYSADVQ 230
Query: 298 REAQRIALR----LGNGNDKKEMNKSDLNTNNLLFKPPVE------SHIQKNKKILKSAK 347
++ +G +NK++L NN + ++ + +QK++KIL++A+
Sbjct: 231 NALEQHLHSSKEFVGKPTILDTINKTELACNNTVIGSQMQLQLGRVTRVQKHRKILRAAR 290
Query: 348 DLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGNEARFI 407
DL D LIIEYRGK MLR+QFE NG+FFK+PYPFVLFYSKF+G+EMCVDARTFGN+ARFI
Sbjct: 291 DLALDTLIIEYRGKVMLRQQFEVNGHFFKKPYPFVLFYSKFNGVEMCVDARTFGNDARFI 350
Query: 408 RRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACLKENPE 467
RRSCTPNAEVRH I DG IHL IY++ +I K E+TIAFD++Y NC YKVDCAC K N
Sbjct: 351 RRSCTPNAEVRHMIADGMIHLCIYAVSAITKDAEVTIAFDYEYSNCNYKVDCACHKGNRN 410
Query: 468 CPVLKRSSESMENI---------NSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTN 518
CP+ KR+ + E G ETRR+K ++ KE + + QN + N
Sbjct: 411 CPIQKRNPNATELPLLPPPPSLPTIGAETRRRKARR-----KELEMEQQN---EASEENN 462
Query: 519 KMKSPETKQRKLSPLRLSVSNNQEPDFIDDIEEKTPISNEVEMESEEQIAERKRKMTREE 578
+S E P +++VS++ E +D+ EEK E ++ +E +A +R TRE+
Sbjct: 463 DQQSQEV------PEKVTVSSDHEE--VDNPEEKPEEEKEEVIDDQENLAHSRR--TRED 512
Query: 579 RKMEAILQAFARLEKREKRREQALER--------ISTAKT----EVKTECKDTQIVSDAE 626
RK+EAI+ AF LEKR+KRR+Q LE+ +T++T E KTE ++++ +
Sbjct: 513 RKVEAIMHAFENLEKRKKRRDQPLEQSNSDVEITTTTSETPVGEETKTEAPESEVSNSVS 572
Query: 627 VIQ-------------------EQAKEENASKPTPAKVNRTKQRKSFSRSRTHIGQQRRR 667
+ + A E+ KP PAK +R + + SR RT Q+ +R
Sbjct: 573 NVTIPSTPQSVGVNTRRSSQAGDIAAEKLVPKPPPAKPSRPRPKSRISRYRTSSAQRLKR 632
Query: 668 HRT-------VSMCSDIQPSSPDI----EVTSQQNDIENTVLTIEPETETALAEIITETE 716
+ +S + + S + E S + EN LT T + IT +
Sbjct: 633 QKQANAQQAELSQAALEEGGSNSLVTPTEAGSLDSSGENRPLTGSDPTVVS----ITGSH 688
Query: 717 VPALNKCPTKYPKTKKHLVNEWLSEKNEKTGKPSDGLSERPLRITTDPEVLATQLNSLPG 776
V N+ +KYPKTKK+LV EWL++K EK P E PLRITTDP VLAT LN LPG
Sbjct: 689 V---NRAASKYPKTKKYLVTEWLNDKAEKQECPV----ECPLRITTDPTVLATTLNMLPG 741
Query: 777 LTYSPHVYSTPKHYIRFTSPFLSEKRRRKEPTENISGSCKKRWLKQALEEENSAILHRFN 836
L +SP + +TPKHYIRF SPF+ E+RRR + SCKKRW+KQALEE + +
Sbjct: 742 LIHSPLICTTPKHYIRFGSPFIPERRRRPLLPDGTFSSCKKRWIKQALEE---GMTQTSS 798
Query: 837 SPCQERSRSPAVNGENKSPL-LLNDSCSLPDLTTPLKKRRFYQLLDSVYSETSTPTPSPY 895
P + R++ + EN S + D+ DL +PLKK + L++ ++
Sbjct: 799 VPQETRTQHLYQSNENSSSSSICKDNA---DLLSPLKKWKSRYLMEQNVTK--------- 846
Query: 896 ATPTHTDITPMDPSFATPPRIKSDDETCRNGYKPIYSPVTPVTPGTPGNTMHFENISSPE 955
+ P++PVTP P + +++P
Sbjct: 847 ----------------------------------LLRPLSPVTPPPPNSGSKSPQLATPG 872
Query: 956 SSPEIKRRTYSQEGYDRSSTMLTLGPFRNSNLTELGLQEIKTIGYTSPRSRTEVNRQCPG 1015
SS + E R+ L P ++LT T+ R T + +
Sbjct: 873 SS-------HPGEEECRNGYSLMFSPV--TSLT------------TASRCNTPLQFELCH 911
Query: 1016 EKEPVSDLQLG----LDA-VEPTALHKTLETPAHDRAEPNSQLDSTH-----SGRGTMYS 1065
K DL L LD+ A +L H P+ L T S G +
Sbjct: 912 RK----DLDLAKVGYLDSNTNSCADRPSLLNSGHSDLAPHPSLGPTSETGFPSRSGDGHQ 967
Query: 1066 SWVKSPD---RTGVNFSVNSNLRDLTPSHQLEVGGGFRISESKCLMQDDTRGMFMETTVF 1122
+ V++ D RT N + + P G + + K L D +
Sbjct: 968 TLVRNSDQAFRTEFNLMYAYSPLNAMPRADGLYRGSPLVGDRKPLHLDGG---------Y 1018
Query: 1123 CTSEDGLVSGFGRTVNDNLIDGNCTP-------------QNPPQKKKVSLLEYRKRQREA 1169
C+ +G S + + +L G+ +P QNPPQ+KKVSLLEYRKR++EA
Sbjct: 1019 CSPAEGFSSRYEHGLMKDLSRGSLSPGGERACEGVPSAPQNPPQRKKVSLLEYRKRKQEA 1078
Query: 1170 RKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSE 1229
+++ + A + G G SSN + H
Sbjct: 1079 KENSAG-------GGGDSAQSKSKSAGAGQGSSNSVSDTGAH------------------ 1113
Query: 1230 ETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVS 1289
V+ ++A + P +++ S S S+ A+ SD R S
Sbjct: 1114 ------GVQGSSARTPSSPHKKFSPSHS-----SMSHLEAVSPSDSRGTSSS-------H 1155
Query: 1290 CSPSHVQSSPSSHSNHIPQLQAKGPVPS-FSELMEDPDPENPEPTTTNECPSPDTSQNTC 1348
C P SS + +L+ G +P + P PT + D+
Sbjct: 1156 CRPQENISSRWMVPTSVERLREGGSIPKVLRSSVRVAQKGEPSPTWESNITEKDSDPADG 1215
Query: 1349 KSPPKMSKPGSPGSVI--PAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSN 1406
+ P +S S G+ + P++ ++ P+ +S S + + Q S
Sbjct: 1216 EGPETLSSALSKGATVYSPSRYSYQLLQCDSPRTESQ-SLLQQSSSPFRGHPTQSPGYSY 1274
Query: 1407 NNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLS 1466
AL +PP + S + S S + H + L P + TP GY S
Sbjct: 1275 RTTALRPGNPPS----HGSSESSLSSTSYSSPAHPVSTDSL--APFTGTP------GYFS 1322
Query: 1467 PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQ 1526
+P S P S +P + P+ + Q+++GTL
Sbjct: 1323 SQPHSGNSTGSNLPRRSCPSSAASPTLQG-----PSDSPTSDSVSQSSTGTL-------- 1369
Query: 1527 SSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSA--NFQNY 1569
SS ++ Q ++ SL S P S+ YQ + SA N Q+Y
Sbjct: 1370 SSTSFPQNSRSSLPSDLRTISLPSAGQSAVYQASRVSAVSNSQHY 1414
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 95.5 bits (236), Expect = 4e-19
Identities = 181/756 (23%), Positives = 255/756 (33%), Gaps = 157/756 (20%)
Query: 1133 FGRTVNDNLIDGNCTPQNPPQKKKVSLLEYRKRQREARKSGSKTE-NFPLISVS------ 1185
FG V L+ NC NPP + V++ + E R + E P+++VS
Sbjct: 418 FGADVR--LMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMPDEPEEPVVAVSSPAVPP 475
Query: 1186 -------PHASGSLSNNGDGCASSNDNGEQ--VDHTASLPLPTPATVYN-ATSEETSNNC 1235
P +S S S++ SS D+ E+ A L A A + N
Sbjct: 476 PTKVVAPPSSSDSSSDSSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNK 535
Query: 1236 PVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHV 1295
P K EK++ E + E+V E +A + K++ S P+ +
Sbjct: 536 PKK----KEKDKKEKKKEKHKRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPM 591
Query: 1296 QSSP-----------------------SSHSNHIPQ---------LQAKGPVPSFSELME 1323
+S P S N +P +Q++ P S E
Sbjct: 592 KSKPPPTYESEEEDKCKPMSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDE 651
Query: 1324 -DPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDS 1382
+ D E +P+T E TS K P+ K VI + K F+ + + S
Sbjct: 652 IEIDFETLKPSTLRELERYVTSCLRKKRKPQAEKV----DVIAGSSKMKGFSSSESESSS 707
Query: 1383 TVSASEAENGVHLKTELQQKQLSNNNQALSKNHP---PQTHVRNSSEQLSQKLPSVPTKL 1439
S+S++E+ +TE+ K + K HP + H + +Q+ Q VP +
Sbjct: 708 ESSSSDSEDS---ETEMAPK-------SKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQ- 756
Query: 1440 HCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNF 1499
PP P + PP P PP QQ P P PQ P +
Sbjct: 757 --PPPPPQQPPP---------------PPPPQQQQQPPPPPPPPSMPQQAAPAMKSSPPP 799
Query: 1500 YPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPP-PPPPSSSYYQ 1558
+ A Q +P Q G++F P G + Q L P PP PP + +
Sbjct: 800 FIATQ-VPVLEPQLP-GSVFD--PIGHFTQPILHLPQPELPPHLPQPPEHSTPPHLNQHA 855
Query: 1559 NQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIH 1618
P A L +L QQ S ALP ++ +T LP P +
Sbjct: 856 VVSPPA-------LHNALPQQPSRPSNRAAALPPKPARPPAVSPALTQTPLLPQ--PPMA 906
Query: 1619 HQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLP 1678
+ PP PP + Q+ V P + P + SQ
Sbjct: 907 QPPQVLLEDEEPPAPPLTSMQMQLYLQQLQK------VQPPTPLLPSVKVQSQ------- 953
Query: 1679 PPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQA 1738
PPPP P PPPHPS +Q Q Q PPP P PPP Q
Sbjct: 954 PPPPLP-------PPPHPS-----VQQQLQQQPPPPPPPQPQPPP-------------QQ 988
Query: 1739 LHHPP----HQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPH 1794
H PP H P F + PP Q H P P QP P P V H
Sbjct: 989 QHQPPPRPVHLQPMQFSTHIQQPPPPQGQQPPH-----PPPGQQPPPPQPAKPQQVIQHH 1043
Query: 1795 LQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQA 1830
P+ S P T H P + PQ +
Sbjct: 1044 HSPRHHKSDPYSTG-----HLREAPSPLMIHSPQMS 1074
Score = 90.5 bits (223), Expect = 1e-17
Identities = 145/598 (24%), Positives = 181/598 (30%), Gaps = 166/598 (27%)
Query: 1278 DKDSGGESPCVSCSPSHVQSSPSS--------------HSNHIPQLQAKGPVPSFSELME 1323
+ +S ES S + +P S H +H QA PVP
Sbjct: 702 ESESSSESSSSDSEDSETEMAPKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQ----QP 757
Query: 1324 DPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDST 1383
P P+ P P P P Q + PP P P +P QA + + P P +
Sbjct: 758 PPPPQQPPP------PPPPQQQ---QQPP----PPPPPPSMPQQAAPAMKSSPPPFIATQ 804
Query: 1384 VSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPP 1443
V E Q P H L Q P +P
Sbjct: 805 VPVLEP-------------------QLPGSVFDPIGHFTQPILHLPQ--PELP------- 836
Query: 1444 SPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAA 1503
PHL PP+ STP QH +S PP+ P +P + P P
Sbjct: 837 -PHLPQPPEHSTPPHLNQHAVVS--PPALHNALPQQPSRPSNRAAALP---------PKP 884
Query: 1504 QNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPS 1563
PA + T L Q P Q Q L PP PP Y
Sbjct: 885 ARPPAVSPALTQTPLLPQPPMAQPP-------QVLLEDEEPPAPPLTSMQMQLY------ 931
Query: 1564 ANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAA 1623
QQ P LP Q P P H PS + Q
Sbjct: 932 -------------LQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPH--PSVQQQLQQQ--- 973
Query: 1624 AVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPP 1683
PPPPPPP P QP QQH P V H+ H+ PPPP
Sbjct: 974 ----PPPPPPPQP------QPPPQQQHQ-----PPPRPV----HLQPMQFSTHIQQPPPP 1014
Query: 1684 PGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVL----ASGHHTTSAQAL 1739
G PPHP G Q PPPP P P V+ + HH + +
Sbjct: 1015 QG-----QQPPHPPPGQQ-------------PPPPQPAKPQQVIQHHHSPRHHKSDPYST 1056
Query: 1740 HHPPHQGPPL---------FPSSAHPTVP-----PYPSQATHHTTLGPGPQHQPSGTGPH 1785
H PL F S H + P P + + + P P H
Sbjct: 1057 GHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQPKKQELRAASVVQPQPLVVVKEEKIH 1116
Query: 1786 CPLPVTGPHL------QPQGPNSIPTPTASGFCPH--PGSVALPHGVQGPQQASPVPG 1835
P+ + P P+ P SI P P P V P ++ P+Q +P PG
Sbjct: 1117 SPIIRSEPFSPSLRPEPPKHPESIKAPVHLPQRPEMKPVDVGRP-VIRPPEQNAPPPG 1173
Score = 40.0 bits (92), Expect = 0.021
Identities = 40/135 (29%), Positives = 47/135 (34%), Gaps = 22/135 (16%)
Query: 1594 TSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPP------PPPPPPAPGPHLVQQPNSH 1647
T Q P TP H P+ P + QT V P PPP PP P P P
Sbjct: 210 TPQPNPPPVQATP-HPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQPV 268
Query: 1648 QQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHP---PPHPSTGLQGLQ 1704
Q H P+ A TP + ++ P P H P PP P T G
Sbjct: 269 QSHP------PIIAATP-QPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLG-- 319
Query: 1705 AQHQHVVNSAPPPPP 1719
Q +S P PP
Sbjct: 320 ---QRRESSRPVKPP 331
Score = 34.3 bits (77), Expect = 1.2
Identities = 36/138 (26%), Positives = 50/138 (36%), Gaps = 23/138 (16%)
Query: 1437 TKLHCPP---SPHLENPPKSSTPH-----TP---VQHGYLSPKPPSQQLGSPYRPHHSQS 1485
T+ PP +P PP +TPH TP VQ ++ PP P P Q
Sbjct: 200 TQASTPPQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP 259
Query: 1486 PQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPP 1545
P PQ AA P T++ T TP+ T ++ PP
Sbjct: 260 PPAPAPQPVQSHPPIIAATPQPVKTKKGVKRKADTTTPT-----TIDPIHE-------PP 307
Query: 1546 PPPPPPPSSSYYQNQQPS 1563
PP P ++ Q ++ S
Sbjct: 308 SLPPEPKTTKLGQRRESS 325
Score = 33.9 bits (76), Expect = 1.5
Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 4/69 (5%)
Query: 12 AETSYLEMAAGSEPESVEASPVVVEKSNSYPHQLYTSSSHHSHSYIGLPYADHNYGARPP 71
+E+S ++ SE E +P KS H HH H + + A +PP
Sbjct: 703 SESSSESSSSDSEDSETEMAP----KSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPP 758
Query: 72 PTPPASPPP 80
P P PPP
Sbjct: 759 PPPQQPPPP 767
Score = 32.7 bits (73), Expect = 3.4
Identities = 35/144 (24%), Positives = 62/144 (43%), Gaps = 20/144 (13%)
Query: 551 EKTPISNEVEMESEEQIAERKRKMTREERKMEAILQAFARLEKREKRR-----------E 599
+K P + +S E+ R+ RE+ + E L+A A ++EK R E
Sbjct: 1207 QKHPTTPSSTAKSSSDSFEQFRRAAREKEEREKALKAQAEHAEKEKERLRQERMRSREDE 1266
Query: 600 QALERISTAKTEV--KTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTK----QRKS 653
ALE+ A E + E + Q + Q+QA A+ A+ ++ + Q++
Sbjct: 1267 DALEQARRAHEEARRRQEQQQQQRQEQQQQQQQQAAAVAAAATPQAQSSQPQSMLDQQRE 1326
Query: 654 FSRSRTHIGQQRRRHRTVSMCSDI 677
+R R Q+RRR ++ D+
Sbjct: 1327 LARKRE---QERRRREAMAATIDM 1347
Score = 31.2 bits (69), Expect = 9.8
Identities = 47/191 (24%), Positives = 64/191 (33%), Gaps = 35/191 (18%)
Query: 1276 RKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPE-NPE--- 1331
R K++G P VS P+ Q+S PQ Q P P + P P P+
Sbjct: 181 RGRKETGTAKPGVSTVPNTTQASTP------PQTQTPQPNPPPVQATPHPFPAVTPDLIV 234
Query: 1332 --PTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTK-PDPQWDSTVSASE 1388
P T P P Q PP+ P +P P Q+H I P P
Sbjct: 235 QTPVMTVVPPQP--LQTPPPVPPQPQPPPAPAPQ-PVQSHPPIIAATPQP---------- 281
Query: 1389 AENGVHLKTELQQKQLSNNNQALSKNH-----PPQTHVRNSSEQLSQKLPSVPTKLHCPP 1443
V K +++K + + H PP+ ++ P P K P
Sbjct: 282 ----VKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLGQRRESSRPVKPPKKDVPD 337
Query: 1444 SPHLENPPKSS 1454
S P KSS
Sbjct: 338 SQQHPAPEKSS 348
Score = 31.2 bits (69), Expect = 9.8
Identities = 39/187 (20%), Positives = 54/187 (28%), Gaps = 33/187 (17%)
Query: 1679 PPPPPPGPAPHHHPPPHPSTGLQG-----LQAQHQHVVNSAPPPP-PPPPPSSVLASGHH 1732
P PPP PH P P +Q + Q PP P PPP P+
Sbjct: 213 PNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAP------- 265
Query: 1733 TTSAQALHHPPHQGPPLFPSSAHP--TVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPV 1790
P PP+ ++ P T +A T P H+P P
Sbjct: 266 --------QPVQSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTK 317
Query: 1791 TGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQN 1850
G + P P HP P+++S V Q+ + F
Sbjct: 318 LGQRRESSRPVKPPKKDVPDSQQHP----------APEKSSKVSEQLKCCSGILKEMFAK 367
Query: 1851 NYHGSGW 1857
+ W
Sbjct: 368 KHAAYAW 374
Score = 31.2 bits (69), Expect = 9.8
Identities = 42/226 (18%), Positives = 87/226 (38%), Gaps = 12/226 (5%)
Query: 606 STAKTEVKTECKDTQIVSDAEVIQEQAKEENASKPTPAKVNRTKQRKSFSRSRTHIGQQR 665
S++ ++ T+ + + +QEQ K + ++ + K +K + ++
Sbjct: 492 SSSDSDSSTDDSEEERAQRLAELQEQLKAVHEQLAALSQPQQNKPKKKEKDKKEKKKEKH 551
Query: 666 RRHRTVSMCSDIQPSSPDIEVTSQQNDIENTVLTIEPETETALAEIITETEVPALNKCPT 725
+R V + P + T + N + V EP + E+E +KC
Sbjct: 552 KRKEEVEENKKSKAKEPPPKKTKKNNSSNSNVSKKEPAPMKSKPPPTYESEEE--DKCKP 609
Query: 726 KYPKTKKHLVNEWLSEKNEKTGKPSDGLSER-PLRITTDPEVLATQLNSLPGLTYSPHVY 784
+ K+ L + EK G+ + R P ++P+ + +L
Sbjct: 610 MSYEEKRQLSLDINKLPGEKLGRVVHIIQSREPSLKNSNPDEIEIDFETLKP-------- 661
Query: 785 STPKHYIRFTSPFLSEKRR-RKEPTENISGSCKKRWLKQALEEENS 829
ST + R+ + L +KR+ + E + I+GS K + + E +S
Sbjct: 662 STLRELERYVTSCLRKKRKPQAEKVDVIAGSSKMKGFSSSESESSS 707
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 94.4 bits (233), Expect = 9e-19
Identities = 187/742 (25%), Positives = 247/742 (33%), Gaps = 147/742 (19%)
Query: 1190 GSLSNNGDGCASSNDNGEQVDHTASLP----LPTPATVYNATSEETSN------NCPVKD 1239
G S G +SS+ E+ TA TP SEE S N P K
Sbjct: 31 GRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKT 90
Query: 1240 ATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSP 1299
T E P+ + + ++ + RS D+D+ SP + SP V++
Sbjct: 91 KTEQELPRPQ----SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY-SPGSVENDS 145
Query: 1300 SSHSNHIPQLQAKG--PVPSFSELMEDPD--PENPEPTTTNECPSPDTSQNTCKSPPK-- 1353
S S + Q A+ P P F + PD P PE + T + PP
Sbjct: 146 DSSSG-LSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR 204
Query: 1354 --MSKPGSPG---SVIPAQAHGKIFTKP-DPQWDSTVSASEAENG--VHLKTELQQKQLS 1405
+ PG+P + P G + P P+ S+ NG H S
Sbjct: 205 MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264
Query: 1406 NNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPP-SPHLENPPKSSTPHTPVQHGY 1464
+ PP T V + LPS P + P +P+L PP P+ +
Sbjct: 265 SGASGAPPTKPPTTPVGGGN------LPSAPPPANFPHVTPNLPPPPALR----PLNNA- 313
Query: 1465 LSPKPPSQQLGSPYRPHHSQSPQVG-------TPQREPQRNFYPAAQNLPANTQQATSGT 1517
S PP LG+ P H SP P E P+ +LP + A +
Sbjct: 314 -SASPPG--LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370
Query: 1518 L-FTQTPSGQSSATYSQFNQQSLNSTAPPPPPP---------PPPSSSYYQNQQPSANFQ 1567
+ F + S SSA S + S +S +P P PPP+S NQ P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPK---- 426
Query: 1568 NYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVP 1627
Y Q SL Q V++ GP P + + + PG F PS Q+ A
Sbjct: 427 -YTQ--PSLPSQAVWSQGPP---PPPPYGRLLANSNAHPGPFPPSTGA----QSTAH--- 473
Query: 1628 PPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPA 1687
PP + H QQ QQ Q HH PPPPG
Sbjct: 474 ----PPVSTHHHHHQQQQQQQQQQQQQ--------------QQQQQQHHGNSGPPPPGAF 515
Query: 1688 PH-------HHPPPH---PSTGL--------QGLQAQHQHVVNSAPPPPPPPPPSSVLAS 1729
PH HH P+ PS G L H V S P PP SS +S
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 1730 GHHTTSAQALHHP-PHQGPPLFPSSAHPTVPPYPSQATHHTTL---------GPGPQHQP 1779
+ + HP P QG P A PP P+ T TL P
Sbjct: 576 SSTSQGSYPCSHPSPSQG----PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631
Query: 1780 SGTGP-----HCPLP-----VTGPHLQPQGPNSIPTPTASGF-----CPHPGSVALPHGV 1824
S GP P P T P +P P S T T G+ PG+
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 1825 QGPQQASPVPGQIPIHRAQVPP 1846
GP P+P P +PP
Sbjct: 692 VGP---GPLPPAGPSGLPSLPP 710
Score = 75.5 bits (184), Expect = 5e-13
Identities = 136/553 (24%), Positives = 179/553 (32%), Gaps = 106/553 (19%)
Query: 1281 SGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPS 1340
+GG+ +P V SS +S + P PV L P P N T N P
Sbjct: 248 NGGKQHPPPTTPISVSSSGASGAP--PTKPPTTPVGG-GNLPSAPPPANFPHVTPNLPPP 304
Query: 1341 PDTS--QNTCKSPPKMSKPGSPGSVIPAQAHGKIF--TKPDPQWDSTVSASE-----AEN 1391
P N SPP + PG + A G+ P P+ T++ S A +
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASS 364
Query: 1392 GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLEN-P 1450
S+++ A + + + S SQ LPS P P S + N P
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 1451 PKSSTPHTPVQ--------------------HGYLSPKPPSQQLGSPYRP-------HHS 1483
PK + P P Q + + P PPS S P HH
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484
Query: 1484 QSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTA 1543
Q Q Q++ Q+ Q N+ G G S + SL S
Sbjct: 485 QQQQQQQQQQQQQQQ----QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 1544 PPPPPP---PPPSS--SYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQT 1598
P PP P PPP S SY Q + + S SQ + S P+ +
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS--------- 591
Query: 1599 VPGHHVTPGHFLPSQNPTIHHQTAAAVV--------------PPPPPP----PPAPGPHL 1640
G P F P T T + V+ PP PPP P+PG +
Sbjct: 592 -QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYK 650
Query: 1641 VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGP----APHHHPPPHP 1696
P ++ S P S G+ PP PG +P P P P
Sbjct: 651 TATPPGYKPGS------------PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP 698
Query: 1697 STGLQGLQAQHQHVVNSAPPPPPPP---PPSSVLASGHHTTSAQALHHPPHQGPPLFPSS 1753
G GL S PPPP P PP S A+ A+ P PP S
Sbjct: 699 PAGPSGLP--------SLPPPPAAPASGPPLS--ATQIKQEPAEEYETPESPVPPARSPS 748
Query: 1754 AHPTVPPYPSQAT 1766
P V PS A+
Sbjct: 749 PPPKVVDVPSHAS 761
Score = 42.4 bits (98), Expect = 0.004
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 40 SYPHQLYTSSSHHSHSYIGLPYADHNYGARP-PPTPPASPPPSVLISKNEVGIFTTPNFD 98
++PH L SSHH+H Y P RP PP P PPP +S ++ G PN
Sbjct: 514 AFPHPLEGGSSHHAHPYAMSPSLG---SLRPYPPGPAHLPPPHSQVSYSQAG----PNGP 566
Query: 99 ETSSATTISTS-EDGSY 114
SS++ S+S GSY
Sbjct: 567 PVSSSSNSSSSTSQGSY 583
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 94.4 bits (233), Expect = 9e-19
Identities = 187/742 (25%), Positives = 247/742 (33%), Gaps = 147/742 (19%)
Query: 1190 GSLSNNGDGCASSNDNGEQVDHTASLP----LPTPATVYNATSEETSN------NCPVKD 1239
G S G +SS+ E+ TA TP SEE S N P K
Sbjct: 31 GRASPGGVSTSSSDGKAEKSRQTAKKARVEEASTPKVNKQGRSEEISESESEETNAPKKT 90
Query: 1240 ATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSP 1299
T E P+ + + ++ + RS D+D+ SP + SP V++
Sbjct: 91 KTEQELPRPQ----SPSDLDSLDGRSLNDDGSSDPRDIDQDNRSTSPSIY-SPGSVENDS 145
Query: 1300 SSHSNHIPQLQAKG--PVPSFSELMEDPD--PENPEPTTTNECPSPDTSQNTCKSPPK-- 1353
S S + Q A+ P P F + PD P PE + T + PP
Sbjct: 146 DSSSG-LSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSR 204
Query: 1354 --MSKPGSPG---SVIPAQAHGKIFTKP-DPQWDSTVSASEAENG--VHLKTELQQKQLS 1405
+ PG+P + P G + P P+ S+ NG H S
Sbjct: 205 MFQAPPGAPPPHPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPTTPISVSS 264
Query: 1406 NNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPP-SPHLENPPKSSTPHTPVQHGY 1464
+ PP T V + LPS P + P +P+L PP P+ +
Sbjct: 265 SGASGAPPTKPPTTPVGGGN------LPSAPPPANFPHVTPNLPPPPALR----PLNNA- 313
Query: 1465 LSPKPPSQQLGSPYRPHHSQSPQVG-------TPQREPQRNFYPAAQNLPANTQQATSGT 1517
S PP LG+ P H SP P E P+ +LP + A +
Sbjct: 314 -SASPPG--LGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPAPP 370
Query: 1518 L-FTQTPSGQSSATYSQFNQQSLNSTAPPPPPP---------PPPSSSYYQNQQPSANFQ 1567
+ F + S SSA S + S +S +P P PPP+S NQ P
Sbjct: 371 MRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPK---- 426
Query: 1568 NYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVP 1627
Y Q SL Q V++ GP P + + + PG F PS Q+ A
Sbjct: 427 -YTQ--PSLPSQAVWSQGPP---PPPPYGRLLANSNAHPGPFPPSTGA----QSTAH--- 473
Query: 1628 PPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPA 1687
PP + H QQ QQ Q HH PPPPG
Sbjct: 474 ----PPVSTHHHHHQQQQQQQQQQQQQ--------------QQQQQQHHGNSGPPPPGAF 515
Query: 1688 PH-------HHPPPH---PSTGL--------QGLQAQHQHVVNSAPPPPPPPPPSSVLAS 1729
PH HH P+ PS G L H V S P PP SS +S
Sbjct: 516 PHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSS 575
Query: 1730 GHHTTSAQALHHP-PHQGPPLFPSSAHPTVPPYPSQATHHTTL---------GPGPQHQP 1779
+ + HP P QG P A PP P+ T TL P
Sbjct: 576 SSTSQGSYPCSHPSPSQG----PQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTA 631
Query: 1780 SGTGP-----HCPLP-----VTGPHLQPQGPNSIPTPTASGF-----CPHPGSVALPHGV 1824
S GP P P T P +P P S T T G+ PG+
Sbjct: 632 SPPGPPPYGKRAPSPGAYKTATPPGYKPGSPPSFRTGTPPGYRGTSPPAGPGTFKPGSPT 691
Query: 1825 QGPQQASPVPGQIPIHRAQVPP 1846
GP P+P P +PP
Sbjct: 692 VGP---GPLPPAGPSGLPSLPP 710
Score = 75.5 bits (184), Expect = 5e-13
Identities = 136/553 (24%), Positives = 179/553 (32%), Gaps = 106/553 (19%)
Query: 1281 SGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPS 1340
+GG+ +P V SS +S + P PV L P P N T N P
Sbjct: 248 NGGKQHPPPTTPISVSSSGASGAP--PTKPPTTPVGG-GNLPSAPPPANFPHVTPNLPPP 304
Query: 1341 PDTS--QNTCKSPPKMSKPGSPGSVIPAQAHGKIF--TKPDPQWDSTVSASE-----AEN 1391
P N SPP + PG + A G+ P P+ T++ S A +
Sbjct: 305 PALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEKGPTLAPSPHSLPPASS 364
Query: 1392 GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLEN-P 1450
S+++ A + + + S SQ LPS P P S + N P
Sbjct: 365 SAPAPPMRFPYSSSSSSSAAASSSSSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQP 424
Query: 1451 PKSSTPHTPVQ--------------------HGYLSPKPPSQQLGSPYRP-------HHS 1483
PK + P P Q + + P PPS S P HH
Sbjct: 425 PKYTQPSLPSQAVWSQGPPPPPPYGRLLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQ 484
Query: 1484 QSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTA 1543
Q Q Q++ Q+ Q N+ G G S + SL S
Sbjct: 485 QQQQQQQQQQQQQQQ----QQQHHGNSGPPPPGAFPHPLEGGSSHHAHPYAMSPSLGSLR 540
Query: 1544 PPPPPP---PPPSS--SYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQT 1598
P PP P PPP S SY Q + + S SQ + S P+ +
Sbjct: 541 PYPPGPAHLPPPHSQVSYSQAGPNGPPVSSSSNSSSSTSQGSYPCSHPSPS--------- 591
Query: 1599 VPGHHVTPGHFLPSQNPTIHHQTAAAVV--------------PPPPPP----PPAPGPHL 1640
G P F P T T + V+ PP PPP P+PG +
Sbjct: 592 -QGPQGAPYPFPPVPTVTTSSATLSTVIATVASSPAGYKTASPPGPPPYGKRAPSPGAYK 650
Query: 1641 VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGP----APHHHPPPHP 1696
P ++ S P S G+ PP PG +P P P P
Sbjct: 651 TATPPGYKPGS------------PPSFRTGTPPGYRGTSPPAGPGTFKPGSPTVGPGPLP 698
Query: 1697 STGLQGLQAQHQHVVNSAPPPPPPP---PPSSVLASGHHTTSAQALHHPPHQGPPLFPSS 1753
G GL S PPPP P PP S A+ A+ P PP S
Sbjct: 699 PAGPSGLP--------SLPPPPAAPASGPPLS--ATQIKQEPAEEYETPESPVPPARSPS 748
Query: 1754 AHPTVPPYPSQAT 1766
P V PS A+
Sbjct: 749 PPPKVVDVPSHAS 761
Score = 42.4 bits (98), Expect = 0.004
Identities = 29/77 (37%), Positives = 38/77 (49%), Gaps = 9/77 (11%)
Query: 40 SYPHQLYTSSSHHSHSYIGLPYADHNYGARP-PPTPPASPPPSVLISKNEVGIFTTPNFD 98
++PH L SSHH+H Y P RP PP P PPP +S ++ G PN
Sbjct: 514 AFPHPLEGGSSHHAHPYAMSPSLG---SLRPYPPGPAHLPPPHSQVSYSQAG----PNGP 566
Query: 99 ETSSATTISTS-EDGSY 114
SS++ S+S GSY
Sbjct: 567 PVSSSSNSSSSTSQGSY 583
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 93.6 bits (231), Expect = 2e-18
Identities = 124/440 (28%), Positives = 147/440 (33%), Gaps = 93/440 (21%)
Query: 1417 PQTHVRNSSEQLSQKLPSVPTKLHCPPSPH-----LENPPKSST---PHTPVQHGYLSPK 1468
PQ +E L P +P PP P L PP P P+ + P
Sbjct: 897 PQPPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAAIPPP 956
Query: 1469 PPSQQLGSPYRPHHSQSPQVGTPQREPQRNF-YPAAQNLPANTQQATSGTLFTQTPSGQS 1527
PP G P P P G P P P LP G P
Sbjct: 957 PPLPGAGIPLPP---PLPGAGIPPPPPLPGAGIPPPPPLP--------GAGIPPPPP--- 1002
Query: 1528 SATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPN 1587
L PPPPP P + P A L G+ P
Sbjct: 1003 -----------LPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGA-------GIPPP 1044
Query: 1588 QALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPP-------PPPPAPGPHL 1640
LPG +P PG +P P A + PPPP PPPP PG +
Sbjct: 1045 PPLPGAG----IPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGAGIPPPPPLPGAGI 1096
Query: 1641 VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGL 1700
P + V P PG+ I PPPPP PG A PPP P G+
Sbjct: 1097 PPPP------PLPGVGIPPPPPLPGAGI---------PPPPPLPG-AGIPPPPPLPGAGI 1140
Query: 1701 QGLQAQHQHVVNSAPP------PPPPPPPSSVLASGHHTTSAQALHHPPHQG-----PPL 1749
+ + PP PPPPP P + + PP G PP
Sbjct: 1141 PPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPP 1200
Query: 1750 FPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCP--LPVTGPHLQPQ-GPNSIPTP 1806
P + P PP P P P P GTG P LPV+GP L PQ G +++PTP
Sbjct: 1201 LPGAGIPPPPPLPGMGIPPA---PAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTP 1257
Query: 1807 TASGFCPHPGSVALPHGVQG 1826
GF P P LP G+ G
Sbjct: 1258 QVCGFLPPP----LPSGLFG 1273
Score = 80.9 bits (198), Expect = 1e-14
Identities = 123/470 (26%), Positives = 151/470 (32%), Gaps = 91/470 (19%)
Query: 1416 PPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHL-----ENPPKSSTPH-------TPVQHG 1463
P + V+ S Q +Q + S P PP P L + P S PH T +H
Sbjct: 791 PRRISVQLDSHQPTQSI-SQP-----PPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHS 844
Query: 1464 YLS--------PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATS 1515
S P PP P S P +G P LP T
Sbjct: 845 VSSAFKNSCNIPSPPPL----PCTESSSSMPGLGMVP--------PPPPPLPGMTVPTLP 892
Query: 1516 GTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGS 1575
T Q P Q + L PPPPP P + P A L G+
Sbjct: 893 STAIPQPPPLQGTEMLPP-PPPPLPGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGA 951
Query: 1576 LSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPP----- 1630
G LP +P PG +P P A + PPPP
Sbjct: 952 AIPPPPPLPGAGIPLPPPLPGAGIPPPPPLPGAGIPPPPPL----PGAGIPPPPPLPGAG 1007
Query: 1631 --PPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTA--GHHLPPPPPPPGP 1686
PPPP PG + P + P PG+ I G +PPPPP PG
Sbjct: 1008 IPPPPPLPGAGIPPPP------PLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPG- 1060
Query: 1687 APHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPP------PPPPSSVLASGHHTTSAQALH 1740
A PPP P G+ PPPPP PPPP A +
Sbjct: 1061 AGIPPPPPLPGAGI--------------PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVG 1106
Query: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGP 1800
PP PP P + P PP P + P P +G P PLP G P P
Sbjct: 1107 IPP---PPPLPGAGIPPPPPLPGAG-----IPPPPPLPGAGIPPPPPLPRVGIPPPPPLP 1158
Query: 1801 NS-IPTP---TASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPP 1846
+ IP P +G P P + P +P P+ A +PP
Sbjct: 1159 GAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPLPGAGIPP 1208
Score = 51.2 bits (121), Expect = 9e-06
Identities = 78/307 (25%), Positives = 95/307 (30%), Gaps = 58/307 (18%)
Query: 1442 PPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYP 1501
PP P L P P P+ + P PP G P P P G P P P
Sbjct: 1009 PPPPPL--PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPP---PLPGAGIPPPPP----LP 1059
Query: 1502 AAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPP------PPPPPSSS 1555
A +P +G P A PPPP PPPPP
Sbjct: 1060 GA-GIPPPPPLPGAGI---PPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPPPPPL-- 1113
Query: 1556 YYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNP 1615
P A L G+ G P + +P PG +P P
Sbjct: 1114 ------PGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPP 1167
Query: 1616 TIHHQTAAAVVPPPP-------PPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHI 1668
A + PPPP PPPP PG + P P + P +
Sbjct: 1168 L----PGAGIPPPPPLPGVGIPPPPPLPGVGIPPPPPL-----------PGAGIPPPPPL 1212
Query: 1669 HSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPP-----PPPPP 1723
G +PP P PP P P PP P + G Q ++ P P PPP P
Sbjct: 1213 ----PGMGIPPAPAPPLPPPGTGIPPPPLLPVSGPPLLPQVGSSTLPTPQVCGFLPPPLP 1268
Query: 1724 SSVLASG 1730
S + G
Sbjct: 1269 SGLFGLG 1275
>gi|112382224 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 93.2 bits (230), Expect = 2e-18
Identities = 166/667 (24%), Positives = 233/667 (34%), Gaps = 129/667 (19%)
Query: 1212 TASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALL 1271
TAS P+ TP+ +SE + +D SE +E E+ + Y
Sbjct: 466 TASTPVNTPSRP--PSSEFLDLSSASEDDFDSEDSEQEL-------------KGYACRHC 510
Query: 1272 LSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPE 1331
+ KD GG + C+ + +P ++ P F + +
Sbjct: 511 FTTTSKDWHHGGRENILLCTDCRIHFKKYGE---LPPIEKPVDPPPFMFKPVKEEDDGLS 567
Query: 1332 PTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAEN 1391
+ S +T +S K G P + + P ST S
Sbjct: 568 GKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAE 627
Query: 1392 GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTK---LHCPPSPHLE 1448
V + +++ S+ L N + V + +E+ + + S TK + P SP E
Sbjct: 628 TVKKSAKKVKEEASS---PLKSNKRQREKVASDTEE-ADRTSSKKTKTQEISRPNSPS-E 682
Query: 1449 NPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPA 1508
+SS + G PK Q + S SP + +PQ + A Q +
Sbjct: 683 GEGESSDSRSVNDEGSSDPKDIDQD-------NRSTSPSIPSPQDNESDSDSSAQQQM-- 733
Query: 1509 NTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPP-----PPPPPPPSSSYYQNQ-QP 1562
QA L Q P+G + A S+APP P P P PS++ Q P
Sbjct: 734 --LQAQPPAL--QAPTGVTPAP----------SSAPPGTPQLPTPGPTPSATAVPPQGSP 779
Query: 1563 SANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTA 1622
+A+ PNQ T VP H+ Q P +H Q
Sbjct: 780 TAS------------------QAPNQPQAPTAP---VPHTHI-------QQAPALHPQR- 810
Query: 1623 AAVVPPPPPPPPAPGPHLVQQP---NSHQQHSVAHVVGPVHAVTPGSHIHSQTAG---HH 1676
PP P PPP P PH QP ++ Q + +H P+H P HS AG H
Sbjct: 811 ----PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP-HSLQAGPLLQH 865
Query: 1677 LPPPPP---PP----GPAPHHHPP----PHPSTGLQGLQA--QHQHVVNSAPPPPPP--- 1720
PP P PP G AP P PH S L Q+ Q Q P PP P
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 925
Query: 1721 ----PPPSSVLASGHHTTSAQALHHPPH-QGPPLFPSSAH----PTVPPYPSQATHHTT- 1770
PPP++ + + QA HPPH GP F +A+ P + P S +THH
Sbjct: 926 PHIKPPPTTPIPQ---LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1771 -----LGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQ 1825
L PQ QP + P P +T P P S P P P P
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042
Query: 1826 GPQQASP 1832
GP +P
Sbjct: 1043 GPPPITP 1049
Score = 85.5 bits (210), Expect = 4e-16
Identities = 97/390 (24%), Positives = 137/390 (35%), Gaps = 65/390 (16%)
Query: 1466 SPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQ----NLPANTQQATSGTLFTQ 1521
S K ++ SP + + Q +V + E R + + P + + + ++
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691
Query: 1522 TPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTV 1581
+ + + S+ +Q + ST+P P P S + SA Q +L T
Sbjct: 692 SVNDEGSSDPKDIDQDN-RSTSPSIPSPQDNES----DSDSSAQQQMLQAQPPALQAPTG 746
Query: 1582 FTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLV 1641
T P+ A PGT LP+ PT +A VPP P + P+
Sbjct: 747 VTPAPSSAPPGTPQ--------------LPTPGPT----PSATAVPPQGSPTASQAPNQP 788
Query: 1642 QQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQ 1701
Q P A P +HI A H PP P P P P HPP P TG
Sbjct: 789 QAPT---------------APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1702 GLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPP----LFPSSAHPT 1757
G + H PP P H + L HP GPP L P ++
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGP--------HSLQAGPLLQHP---GPPQPFGLPPQASQGQ 882
Query: 1758 VP--PYPSQATHHTTLG-PGPQ-----HQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTAS 1809
P P+ A HT+L P Q QP P P P+ PH++P IP A
Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 1810 GFCPHPGSVALPHGVQGPQQASPVPGQIPI 1839
HP ++ P P P P+
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPL 972
Score = 81.3 bits (199), Expect = 8e-15
Identities = 148/615 (24%), Positives = 210/615 (34%), Gaps = 149/615 (24%)
Query: 1185 SPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASE 1244
SP A+ S S+N + + ++V AS PL + E+ +++ D T+S+
Sbjct: 613 SPSAA-STSSNDSKAETVKKSAKKVKEEASSPLKSN----KRQREKVASDTEEADRTSSK 667
Query: 1245 KNEPEVQWTASTSVEQVRERSYQRALLL--SDHRKDKDSGGESPCVSCSPSHVQSSPSSH 1302
K + + ++ E E S R++ S KD D S S S S
Sbjct: 668 KTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 727
Query: 1303 SNHIPQLQAKGPVPSFSELMEDPDPENPEPTT----TNECPSPDTSQNTCKSPPKMSKPG 1358
S LQA+ P ++ P P P++ T + P+P + + PP+ G
Sbjct: 728 SAQQQMLQAQPPA------LQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----G 777
Query: 1359 SPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQ 1418
SP +AS+A N T P
Sbjct: 778 SP------------------------TASQAPNQPQAPTA----------------PVPH 797
Query: 1419 THVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPY 1478
TH++ + Q+ PPSPH PP +PH P+Q P + G P
Sbjct: 798 THIQQAPALHPQR----------PPSPH---PPPHPSPHPPLQ-------PLTGSAGQPS 837
Query: 1479 RPHHSQSPQVGTPQREP---------QRNFYPAAQNLP--ANTQQATSGTLFTQTPSGQS 1527
P H+Q P G P Q P LP A+ QA GT +P+
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAY 893
Query: 1528 SATYSQF--NQQSLNSTAPP-----PPPP-------PPPSSSYYQNQQPSANFQNYNQLK 1573
T Q +Q +L S PP PP P PPP++ Q P A+ ++ L
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH-KHPPHLS 952
Query: 1574 GSLSQQTVFTSGPNQALPGTTSQQT--VPGHHVTPGHFLPSQNPTIHHQ------TAAAV 1625
G P AL +S T P H P +P P T +
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 1626 VPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685
+PPPP P G H V QH V G +TP + + T PP G
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPF--VPGGPPPITPPTCPSTST---------PPAG 1061
Query: 1686 PAPHHHPP-----------------PHPSTGLQGLQAQHQHVVNSAPPPP--PPPPPSSV 1726
P PP P P+ ++ S PPPP P P P+ V
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 1727 LASGHHTTSAQALHH 1741
H + SA+ H
Sbjct: 1122 DTPSHASQSARFYKH 1136
Score = 69.3 bits (168), Expect = 3e-11
Identities = 117/532 (21%), Positives = 176/532 (33%), Gaps = 104/532 (19%)
Query: 1184 VSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVY-NATSE---ETSNNCPVKD 1239
V AS L +N + E+ D T+S T N+ SE E+S++ V D
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695
Query: 1240 ATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQS-- 1297
+S+ + ++Q + D+ D DS + + P +Q+
Sbjct: 696 EGSSDPKD----------IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 745
Query: 1298 ----SPSSHSNHIPQLQAKGPVPSF-----------SELMEDPD-PENPEPTT------- 1334
+PSS PQL GP PS S+ P P P P T
Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 805
Query: 1335 --TNECPSPDTSQNTCKSPPKMSKPGSPGSV-IPAQAH----------------GKIFTK 1375
PSP + PP GS G P+ A G +
Sbjct: 806 LHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865
Query: 1376 PDPQWDSTVSASEAENGVHLKTELQQK------QLSNNNQALSKNHPPQTHVRNSSEQLS 1429
P P + ++ L T QL + AL PP+
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR----------E 915
Query: 1430 QKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVG 1489
Q LP P + PH++ PP + P P + PP SP+ + + P
Sbjct: 916 QPLPPAPLAM-----PHIKPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPPPPA 968
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
+P + + P S L +P+ T SQ PPPP
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQ--------NLPPPPAS 1019
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGS---LSQQTVFTSGPNQALPGTTSQQTVPGHHVTP 1606
PP+ + QP F + + G ++ T ++ A PGT++Q G +
Sbjct: 1020 HPPTGLHQVAPQPP--FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077
Query: 1607 GHFLPSQN---PTIHHQTAAA------VVPPPPPPPPAPGPHLVQQPNSHQQ 1649
G + PT+ + A PPPPP P+P P +V P+ Q
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 1129
Score = 37.4 bits (85), Expect = 0.14
Identities = 42/131 (32%), Positives = 48/131 (36%), Gaps = 34/131 (25%)
Query: 1639 HLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG--PAPHHHPPPHP 1696
HL QQ HQ + GPVH + + TAG HL P PPG P P PPH
Sbjct: 1437 HLHQQDPLHQGSA-----GPVHPL-----VDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 1486
Query: 1697 STGLQGLQAQHQHVVNSAPPPP------PPPPPSSVLASGHHTTSA---------QALHH 1741
L +H V P P PPP ++ H SA Q LH
Sbjct: 1487 HEML-------RHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHG 1539
Query: 1742 PPHQGPPLFPS 1752
PH PS
Sbjct: 1540 HPHMHGGHLPS 1550
Score = 32.0 bits (71), Expect = 5.8
Identities = 33/129 (25%), Positives = 46/129 (35%), Gaps = 11/129 (8%)
Query: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGT 1782
P+S ++ +++++ P T P PS + + Q Q
Sbjct: 677 PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQA 736
Query: 1783 GP---HCPLPVT-GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIP 1838
P P VT P P G +PTP P P + A+P QG AS P Q
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-----PTPSATAVPP--QGSPTASQAPNQPQ 789
Query: 1839 IHRAQVPPT 1847
A VP T
Sbjct: 790 APTAPVPHT 798
>gi|112382216 atrophin-1 like protein isoform a [Homo sapiens]
Length = 1566
Score = 93.2 bits (230), Expect = 2e-18
Identities = 166/667 (24%), Positives = 233/667 (34%), Gaps = 129/667 (19%)
Query: 1212 TASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALL 1271
TAS P+ TP+ +SE + +D SE +E E+ + Y
Sbjct: 466 TASTPVNTPSRP--PSSEFLDLSSASEDDFDSEDSEQEL-------------KGYACRHC 510
Query: 1272 LSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPE 1331
+ KD GG + C+ + +P ++ P F + +
Sbjct: 511 FTTTSKDWHHGGRENILLCTDCRIHFKKYGE---LPPIEKPVDPPPFMFKPVKEEDDGLS 567
Query: 1332 PTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAEN 1391
+ S +T +S K G P + + P ST S
Sbjct: 568 GKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAE 627
Query: 1392 GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTK---LHCPPSPHLE 1448
V + +++ S+ L N + V + +E+ + + S TK + P SP E
Sbjct: 628 TVKKSAKKVKEEASS---PLKSNKRQREKVASDTEE-ADRTSSKKTKTQEISRPNSPS-E 682
Query: 1449 NPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPA 1508
+SS + G PK Q + S SP + +PQ + A Q +
Sbjct: 683 GEGESSDSRSVNDEGSSDPKDIDQD-------NRSTSPSIPSPQDNESDSDSSAQQQM-- 733
Query: 1509 NTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPP-----PPPPPPPSSSYYQNQ-QP 1562
QA L Q P+G + A S+APP P P P PS++ Q P
Sbjct: 734 --LQAQPPAL--QAPTGVTPAP----------SSAPPGTPQLPTPGPTPSATAVPPQGSP 779
Query: 1563 SANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTA 1622
+A+ PNQ T VP H+ Q P +H Q
Sbjct: 780 TAS------------------QAPNQPQAPTAP---VPHTHI-------QQAPALHPQR- 810
Query: 1623 AAVVPPPPPPPPAPGPHLVQQP---NSHQQHSVAHVVGPVHAVTPGSHIHSQTAG---HH 1676
PP P PPP P PH QP ++ Q + +H P+H P HS AG H
Sbjct: 811 ----PPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP-HSLQAGPLLQH 865
Query: 1677 LPPPPP---PP----GPAPHHHPP----PHPSTGLQGLQA--QHQHVVNSAPPPPPP--- 1720
PP P PP G AP P PH S L Q+ Q Q P PP P
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 925
Query: 1721 ----PPPSSVLASGHHTTSAQALHHPPH-QGPPLFPSSAH----PTVPPYPSQATHHTT- 1770
PPP++ + + QA HPPH GP F +A+ P + P S +THH
Sbjct: 926 PHIKPPPTTPIPQ---LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 982
Query: 1771 -----LGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQ 1825
L PQ QP + P P +T P P S P P P P
Sbjct: 983 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 1042
Query: 1826 GPQQASP 1832
GP +P
Sbjct: 1043 GPPPITP 1049
Score = 85.5 bits (210), Expect = 4e-16
Identities = 97/390 (24%), Positives = 137/390 (35%), Gaps = 65/390 (16%)
Query: 1466 SPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQ----NLPANTQQATSGTLFTQ 1521
S K ++ SP + + Q +V + E R + + P + + + ++
Sbjct: 632 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 691
Query: 1522 TPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTV 1581
+ + + S+ +Q + ST+P P P S + SA Q +L T
Sbjct: 692 SVNDEGSSDPKDIDQDN-RSTSPSIPSPQDNES----DSDSSAQQQMLQAQPPALQAPTG 746
Query: 1582 FTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLV 1641
T P+ A PGT LP+ PT +A VPP P + P+
Sbjct: 747 VTPAPSSAPPGTPQ--------------LPTPGPT----PSATAVPPQGSPTASQAPNQP 788
Query: 1642 QQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQ 1701
Q P A P +HI A H PP P P P P HPP P TG
Sbjct: 789 QAPT---------------APVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSA 833
Query: 1702 GLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPP----LFPSSAHPT 1757
G + H PP P H + L HP GPP L P ++
Sbjct: 834 GQPSAPSHAQPPLHGQGPPGP--------HSLQAGPLLQHP---GPPQPFGLPPQASQGQ 882
Query: 1758 VP--PYPSQATHHTTLG-PGPQ-----HQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTAS 1809
P P+ A HT+L P Q QP P P P+ PH++P IP A
Sbjct: 883 APLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAP 942
Query: 1810 GFCPHPGSVALPHGVQGPQQASPVPGQIPI 1839
HP ++ P P P P+
Sbjct: 943 QAHKHPPHLSGPSPFSMNANLPPPPALKPL 972
Score = 81.3 bits (199), Expect = 8e-15
Identities = 148/615 (24%), Positives = 210/615 (34%), Gaps = 149/615 (24%)
Query: 1185 SPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASE 1244
SP A+ S S+N + + ++V AS PL + E+ +++ D T+S+
Sbjct: 613 SPSAA-STSSNDSKAETVKKSAKKVKEEASSPLKSN----KRQREKVASDTEEADRTSSK 667
Query: 1245 KNEPEVQWTASTSVEQVRERSYQRALLL--SDHRKDKDSGGESPCVSCSPSHVQSSPSSH 1302
K + + ++ E E S R++ S KD D S S S S
Sbjct: 668 KTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 727
Query: 1303 SNHIPQLQAKGPVPSFSELMEDPDPENPEPTT----TNECPSPDTSQNTCKSPPKMSKPG 1358
S LQA+ P ++ P P P++ T + P+P + + PP+ G
Sbjct: 728 SAQQQMLQAQPPA------LQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----G 777
Query: 1359 SPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQ 1418
SP +AS+A N T P
Sbjct: 778 SP------------------------TASQAPNQPQAPTA----------------PVPH 797
Query: 1419 THVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPY 1478
TH++ + Q+ PPSPH PP +PH P+Q P + G P
Sbjct: 798 THIQQAPALHPQR----------PPSPH---PPPHPSPHPPLQ-------PLTGSAGQPS 837
Query: 1479 RPHHSQSPQVGTPQREP---------QRNFYPAAQNLP--ANTQQATSGTLFTQTPSGQS 1527
P H+Q P G P Q P LP A+ QA GT +P+
Sbjct: 838 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAY 893
Query: 1528 SATYSQF--NQQSLNSTAPP-----PPPP-------PPPSSSYYQNQQPSANFQNYNQLK 1573
T Q +Q +L S PP PP P PPP++ Q P A+ ++ L
Sbjct: 894 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH-KHPPHLS 952
Query: 1574 GSLSQQTVFTSGPNQALPGTTSQQT--VPGHHVTPGHFLPSQNPTIHHQ------TAAAV 1625
G P AL +S T P H P +P P T +
Sbjct: 953 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 1012
Query: 1626 VPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685
+PPPP P G H V QH V G +TP + + T PP G
Sbjct: 1013 LPPPPASHPPTGLHQVAPQPPFAQHPF--VPGGPPPITPPTCPSTST---------PPAG 1061
Query: 1686 PAPHHHPP-----------------PHPSTGLQGLQAQHQHVVNSAPPPP--PPPPPSSV 1726
P PP P P+ ++ S PPPP P P P+ V
Sbjct: 1062 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 1121
Query: 1727 LASGHHTTSAQALHH 1741
H + SA+ H
Sbjct: 1122 DTPSHASQSARFYKH 1136
Score = 69.3 bits (168), Expect = 3e-11
Identities = 117/532 (21%), Positives = 176/532 (33%), Gaps = 104/532 (19%)
Query: 1184 VSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVY-NATSE---ETSNNCPVKD 1239
V AS L +N + E+ D T+S T N+ SE E+S++ V D
Sbjct: 636 VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 695
Query: 1240 ATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQS-- 1297
+S+ + ++Q + D+ D DS + + P +Q+
Sbjct: 696 EGSSDPKD----------IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 745
Query: 1298 ----SPSSHSNHIPQLQAKGPVPSF-----------SELMEDPD-PENPEPTT------- 1334
+PSS PQL GP PS S+ P P P P T
Sbjct: 746 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 805
Query: 1335 --TNECPSPDTSQNTCKSPPKMSKPGSPGSV-IPAQAH----------------GKIFTK 1375
PSP + PP GS G P+ A G +
Sbjct: 806 LHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 865
Query: 1376 PDPQWDSTVSASEAENGVHLKTELQQK------QLSNNNQALSKNHPPQTHVRNSSEQLS 1429
P P + ++ L T QL + AL PP+
Sbjct: 866 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR----------E 915
Query: 1430 QKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVG 1489
Q LP P + PH++ PP + P P + PP SP+ + + P
Sbjct: 916 QPLPPAPLAM-----PHIKPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPPPPA 968
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
+P + + P S L +P+ T SQ PPPP
Sbjct: 969 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQ--------NLPPPPAS 1019
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGS---LSQQTVFTSGPNQALPGTTSQQTVPGHHVTP 1606
PP+ + QP F + + G ++ T ++ A PGT++Q G +
Sbjct: 1020 HPPTGLHQVAPQPP--FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 1077
Query: 1607 GHFLPSQN---PTIHHQTAAA------VVPPPPPPPPAPGPHLVQQPNSHQQ 1649
G + PT+ + A PPPPP P+P P +V P+ Q
Sbjct: 1078 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 1129
Score = 37.4 bits (85), Expect = 0.14
Identities = 42/131 (32%), Positives = 48/131 (36%), Gaps = 34/131 (25%)
Query: 1639 HLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG--PAPHHHPPPHP 1696
HL QQ HQ + GPVH + + TAG HL P PPG P P PPH
Sbjct: 1437 HLHQQDPLHQGSA-----GPVHPL-----VDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 1486
Query: 1697 STGLQGLQAQHQHVVNSAPPPP------PPPPPSSVLASGHHTTSA---------QALHH 1741
L +H V P P PPP ++ H SA Q LH
Sbjct: 1487 HEML-------RHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHG 1539
Query: 1742 PPHQGPPLFPS 1752
PH PS
Sbjct: 1540 HPHMHGGHLPS 1550
Score = 32.0 bits (71), Expect = 5.8
Identities = 33/129 (25%), Positives = 46/129 (35%), Gaps = 11/129 (8%)
Query: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGT 1782
P+S ++ +++++ P T P PS + + Q Q
Sbjct: 677 PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQA 736
Query: 1783 GP---HCPLPVT-GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIP 1838
P P VT P P G +PTP P P + A+P QG AS P Q
Sbjct: 737 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-----PTPSATAVPP--QGSPTASQAPNQPQ 789
Query: 1839 IHRAQVPPT 1847
A VP T
Sbjct: 790 APTAPVPHT 798
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 92.4 bits (228), Expect = 4e-18
Identities = 115/427 (26%), Positives = 158/427 (37%), Gaps = 69/427 (16%)
Query: 1466 SPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQ----NLPANTQQATSGTLFTQ 1521
S K ++ SP + + Q +V + E R + + P + + + ++
Sbjct: 78 SAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSR 137
Query: 1522 TPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTV 1581
+ + + S+ +Q + ST+P P P S + SA Q +L T
Sbjct: 138 SVNDEGSSDPKDIDQDN-RSTSPSIPSPQDNES----DSDSSAQQQMLQAQPPALQAPTG 192
Query: 1582 FTSGPNQALPGTTSQQT---VPGHHVTPGHFLPSQN-------------PTIHHQTAAAV 1625
T P+ A PGT T P P P+ + P H Q A A+
Sbjct: 193 VTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252
Query: 1626 VPPPPP---PPPAPGPHLVQQP---NSHQQHSVAHVVGPVHAVTPGSHIHSQTAG---HH 1676
P PP PPP P PH QP ++ Q + +H P+H P HS AG H
Sbjct: 253 HPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP-HSLQAGPLLQH 311
Query: 1677 LPPPPP---PP----GPAPHHHPP----PHPSTGLQGLQA--QHQHVVNSAPPPPPP--- 1720
PP P PP G AP P PH S L Q+ Q Q P PP P
Sbjct: 312 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAM 371
Query: 1721 ----PPPSSVLASGHHTTSAQALHHPPH-QGPPLFPSSAH----PTVPPYPSQATHHTT- 1770
PPP++ + + QA HPPH GP F +A+ P + P S +THH
Sbjct: 372 PHIKPPPTTPIPQ---LPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPS 428
Query: 1771 -----LGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQ 1825
L PQ QP + P P +T P P S P P P P
Sbjct: 429 AHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPG 488
Query: 1826 GPQQASP 1832
GP +P
Sbjct: 489 GPPPITP 495
Score = 89.4 bits (220), Expect = 3e-17
Identities = 110/413 (26%), Positives = 143/413 (34%), Gaps = 80/413 (19%)
Query: 1444 SPHLENPPKS-STPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPA 1502
SP + +P + S + Q L +PP+ Q + P S +P GTPQ A
Sbjct: 158 SPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPP-GTPQLPTPGPTPSA 216
Query: 1503 AQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQP 1562
P + A+ Q P+ T+ Q +L+ PP P PPP S +
Sbjct: 217 TAVPPQGSPTASQAPNQPQAPTAPVPHTHIQ-QAPALHPQRPPSPHPPPHPSPH------ 269
Query: 1563 SANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTA 1622
P Q L G+ Q + P H P H P H A
Sbjct: 270 ----------------------PPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP--HSLQA 305
Query: 1623 AAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPP-- 1680
++ P PP P P Q + S A P S Q+A PP
Sbjct: 306 GPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPAS----QSALQSQQPPRE 361
Query: 1681 -PPPPGPAPHHHPPPHPSTGLQGLQAQ--HQHVVNSAPPPP-------PPPPPSSVLASG 1730
P PP P H P P+T + L A H+H + + P P PPPP L+S
Sbjct: 362 QPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS- 420
Query: 1731 HHTTSAQALHHPPHQGPP---LFPSSAH-PTVPPYPSQATHHTTLGPGP-QHQPSGTG-- 1783
+ HHPP PP L P S P+ P P T L P P H P+G
Sbjct: 421 ------LSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQV 474
Query: 1784 ------------PHCPLPVTGP-----HLQPQGPNSIPTPTASGFCPHPGSVA 1819
P P P+T P P GP + P SG GS+A
Sbjct: 475 APQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIA 527
Score = 81.3 bits (199), Expect = 8e-15
Identities = 148/615 (24%), Positives = 210/615 (34%), Gaps = 149/615 (24%)
Query: 1185 SPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNATSEETSNNCPVKDATASE 1244
SP A+ S S+N + + ++V AS PL + E+ +++ D T+S+
Sbjct: 59 SPSAA-STSSNDSKAETVKKSAKKVKEEASSPLKSN----KRQREKVASDTEEADRTSSK 113
Query: 1245 KNEPEVQWTASTSVEQVRERSYQRALLL--SDHRKDKDSGGESPCVSCSPSHVQSSPSSH 1302
K + + ++ E E S R++ S KD D S S S S
Sbjct: 114 KTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDS 173
Query: 1303 SNHIPQLQAKGPVPSFSELMEDPDPENPEPTT----TNECPSPDTSQNTCKSPPKMSKPG 1358
S LQA+ P ++ P P P++ T + P+P + + PP+ G
Sbjct: 174 SAQQQMLQAQPPA------LQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQ----G 223
Query: 1359 SPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQ 1418
SP +AS+A N T P
Sbjct: 224 SP------------------------TASQAPNQPQAPTA----------------PVPH 243
Query: 1419 THVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPY 1478
TH++ + Q+ PPSPH PP +PH P+Q P + G P
Sbjct: 244 THIQQAPALHPQR----------PPSPH---PPPHPSPHPPLQ-------PLTGSAGQPS 283
Query: 1479 RPHHSQSPQVGTPQREP---------QRNFYPAAQNLP--ANTQQATSGTLFTQTPSGQS 1527
P H+Q P G P Q P LP A+ QA GT +P+
Sbjct: 284 APSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGT----SPAAAY 339
Query: 1528 SATYSQF--NQQSLNSTAPP-----PPPP-------PPPSSSYYQNQQPSANFQNYNQLK 1573
T Q +Q +L S PP PP P PPP++ Q P A+ ++ L
Sbjct: 340 PHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAH-KHPPHLS 398
Query: 1574 GSLSQQTVFTSGPNQALPGTTSQQT--VPGHHVTPGHFLPSQNPTIHHQ------TAAAV 1625
G P AL +S T P H P +P P T +
Sbjct: 399 GPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQN 458
Query: 1626 VPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685
+PPPP P G H V QH V G +TP + + T PP G
Sbjct: 459 LPPPPASHPPTGLHQVAPQPPFAQHPF--VPGGPPPITPPTCPSTST---------PPAG 507
Query: 1686 PAPHHHPP-----------------PHPSTGLQGLQAQHQHVVNSAPPPP--PPPPPSSV 1726
P PP P P+ ++ S PPPP P P P+ V
Sbjct: 508 PGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVV 567
Query: 1727 LASGHHTTSAQALHH 1741
H + SA+ H
Sbjct: 568 DTPSHASQSARFYKH 582
Score = 69.3 bits (168), Expect = 3e-11
Identities = 117/532 (21%), Positives = 176/532 (33%), Gaps = 104/532 (19%)
Query: 1184 VSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVY-NATSE---ETSNNCPVKD 1239
V AS L +N + E+ D T+S T N+ SE E+S++ V D
Sbjct: 82 VKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVND 141
Query: 1240 ATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQS-- 1297
+S+ + ++Q + D+ D DS + + P +Q+
Sbjct: 142 EGSSDPKD----------IDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPT 191
Query: 1298 ----SPSSHSNHIPQLQAKGPVPSF-----------SELMEDPD-PENPEPTT------- 1334
+PSS PQL GP PS S+ P P P P T
Sbjct: 192 GVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPA 251
Query: 1335 --TNECPSPDTSQNTCKSPPKMSKPGSPGSV-IPAQAH----------------GKIFTK 1375
PSP + PP GS G P+ A G +
Sbjct: 252 LHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQH 311
Query: 1376 PDPQWDSTVSASEAENGVHLKTELQQK------QLSNNNQALSKNHPPQTHVRNSSEQLS 1429
P P + ++ L T QL + AL PP+
Sbjct: 312 PGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPR----------E 361
Query: 1430 QKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVG 1489
Q LP P + PH++ PP + P P + PP SP+ + + P
Sbjct: 362 QPLPPAPLAM-----PHIKPPPTTPIPQLPAPQAH--KHPPHLSGPSPFSMNANLPPPPA 414
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
+P + + P S L +P+ T SQ PPPP
Sbjct: 415 LKPLSSLSTHHPPSAHPPPLQLMPQSQPL-PSSPAQPPGLTQSQ--------NLPPPPAS 465
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGS---LSQQTVFTSGPNQALPGTTSQQTVPGHHVTP 1606
PP+ + QP F + + G ++ T ++ A PGT++Q G +
Sbjct: 466 HPPTGLHQVAPQPP--FAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASG 523
Query: 1607 GHFLPSQN---PTIHHQTAAA------VVPPPPPPPPAPGPHLVQQPNSHQQ 1649
G + PT+ + A PPPPP P+P P +V P+ Q
Sbjct: 524 GSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQ 575
Score = 37.4 bits (85), Expect = 0.14
Identities = 42/131 (32%), Positives = 48/131 (36%), Gaps = 34/131 (25%)
Query: 1639 HLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG--PAPHHHPPPHP 1696
HL QQ HQ + GPVH + + TAG HL P PPG P P PPH
Sbjct: 883 HLHQQDPLHQGSA-----GPVHPL-----VDPLTAGPHLARFPYPPGTLPNPLLGQPPHE 932
Query: 1697 STGLQGLQAQHQHVVNSAPPPP------PPPPPSSVLASGHHTTSA---------QALHH 1741
L +H V P P PPP ++ H SA Q LH
Sbjct: 933 HEML-------RHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHG 985
Query: 1742 PPHQGPPLFPS 1752
PH PS
Sbjct: 986 HPHMHGGHLPS 996
Score = 32.0 bits (71), Expect = 5.8
Identities = 33/129 (25%), Positives = 46/129 (35%), Gaps = 11/129 (8%)
Query: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGT 1782
P+S ++ +++++ P T P PS + + Q Q
Sbjct: 123 PNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQA 182
Query: 1783 GP---HCPLPVT-GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIP 1838
P P VT P P G +PTP P P + A+P QG AS P Q
Sbjct: 183 QPPALQAPTGVTPAPSSAPPGTPQLPTPG-----PTPSATAVPP--QGSPTASQAPNQPQ 235
Query: 1839 IHRAQVPPT 1847
A VP T
Sbjct: 236 APTAPVPHT 244
>gi|42544125 splicing factor 1 isoform 2 [Homo sapiens]
Length = 638
Score = 90.9 bits (224), Expect = 1e-17
Identities = 99/328 (30%), Positives = 121/328 (36%), Gaps = 77/328 (23%)
Query: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602
AP PPPP S Q++ P N SGP+++ P PG
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMN------------------SGPSESRPYHGMHGGGPGG 389
Query: 1603 HVTPGHFLPSQNPTI------HHQTAAAVVPPPP-----PPPPAPGPHLVQQPNSHQQHS 1651
H P P++ H PPPP PPP GPH P H
Sbjct: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH---PPGHHGPPP 446
Query: 1652 VAHVVGPVHAVTP-GSHIHSQTAGHHLPPPPP-----PPGPAPHHHPPPHPSTGLQGLQA 1705
+ +G TP GS ++ G + PPPP PP P P PPP PS L Q
Sbjct: 447 MDQYLGS----TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502
Query: 1706 QHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP-TVPPYPSQ 1764
Q Q PPPPPPPSS +AS + P Q +SA ++PP+ Q
Sbjct: 503 QQQQ-------PPPPPPPSSSMAS--------STPLPWQQNTTTTTTSAGTGSIPPWQQQ 547
Query: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVAL---P 1821
PQ Q G PLP P +QP P P P P PGS + P
Sbjct: 548 QAAAAASPGAPQMQ--GNPTMVPLP---PGVQPPLPPGAPPPPPP---PPPGSAGMMIPP 599
Query: 1822 HGVQGPQQAS--------PVPGQIPIHR 1841
G GP S +PG+ P R
Sbjct: 600 RGGDGPSHESEDFPRPLVTLPGRQPQQR 627
Score = 61.2 bits (147), Expect = 9e-09
Identities = 70/240 (29%), Positives = 78/240 (32%), Gaps = 58/240 (24%)
Query: 1621 TAAAVVPPPPPP---PPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHL 1677
T A P P P PP P Q +S P H + G
Sbjct: 338 TPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG----------- 386
Query: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQH--QHVVNSAPPP--PPPPPPSSVLASGHHT 1733
P PG PH P P PS L G H QH N PPP PPPPP +
Sbjct: 387 ---PGGPGGGPHSFPHPLPS--LTGGHGGHPMQHNPNGPPPPWMQPPPPPMN-------- 433
Query: 1734 TSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ--HQPSGTGPHCPLPVT 1791
Q H P H GPP Q T +G G HQ G P P+ +
Sbjct: 434 ---QGPHPPGHHGPPPM------------DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
Query: 1792 GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNN 1851
P P P SG P P S LP Q QQ P P + P +Q N
Sbjct: 479 PP----------PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Score = 57.0 bits (136), Expect = 2e-07
Identities = 62/213 (29%), Positives = 74/213 (34%), Gaps = 58/213 (27%)
Query: 1442 PPSPHLENPPK--SSTPHTPVQHGYLSPKPPSQQLGSP------YRPHHSQS----PQVG 1489
PP P ++ PP + PH P HG P P Q LGS YR H + P +G
Sbjct: 420 PPPPWMQPPPPPMNQGPHPPGHHG---PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
P P+ Q P PSG Q Q PPPP
Sbjct: 477 MMPPPPPP---PSGQPPP--------------PPSGPLPPWQQQQQQ---------PPPP 510
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF 1609
PPPSSS + L + T TS ++P QQ +PG
Sbjct: 511 PPPSSS----------MASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA--ASPGAP 558
Query: 1610 LPSQNPTIHHQTAAAVVP-----PPPPPPPAPG 1637
NPT+ P PPPPPPP PG
Sbjct: 559 QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPG 591
Score = 46.6 bits (109), Expect = 2e-04
Identities = 37/121 (30%), Positives = 43/121 (35%), Gaps = 16/121 (13%)
Query: 1442 PPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTP----QREPQR 1497
PP P + PP S P P Q P PP P S S TP Q
Sbjct: 482 PPPPSGQPPPPPSGPLPPWQQQQQQPPPP---------PPPSSSMASSTPLPWQQNTTTT 532
Query: 1498 NFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFN---QQSLNSTAPPPPPPPPPSS 1554
++P QQ + P Q + T Q L APPPPPPPPP S
Sbjct: 533 TTSAGTGSIPPWQQQQAAAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGS 592
Query: 1555 S 1555
+
Sbjct: 593 A 593
Score = 32.0 bits (71), Expect = 5.8
Identities = 42/191 (21%), Positives = 57/191 (29%), Gaps = 32/191 (16%)
Query: 1310 QAKG--PVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQ 1367
Q KG P P + P P + +P P P Q + PP S S P
Sbjct: 465 QGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPL- 523
Query: 1368 AHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQ 1427
W + + G QQ+Q + A S P
Sbjct: 524 -----------PWQQNTTTTTTSAGTGSIPPWQQQQAA---AAASPGAP----------- 558
Query: 1428 LSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPK-PPSQQLGSPYRPHHSQSP 1486
++ PT + PP PP + P P G PP G + P
Sbjct: 559 ---QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPPPGSAGMMIPPRGGDGPSHESEDFPRP 615
Query: 1487 QVGTPQREPQR 1497
V P R+PQ+
Sbjct: 616 LVTLPGRQPQQ 626
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 90.9 bits (224), Expect = 1e-17
Identities = 99/323 (30%), Positives = 119/323 (36%), Gaps = 66/323 (20%)
Query: 1544 PPPPPPPPPSSSYYQNQQPSANFQNY-NQLKGSLSQQTVFTSGP---NQALPGTTSQQTV 1599
PPPPPPPPP Y++Q+P +N ++ L GS + F P QA ++S +
Sbjct: 1181 PPPPPPPPPEE--YKSQRPVSNSSSFLGSLFGSKRGKGPFQMPPPPTGQASASSSSASST 1238
Query: 1600 PGHHVTPGH--------FLP---SQNPTIHHQTAAAVVPPPPP--PPPAPG--PHLVQQP 1644
HH H LP S+ +H Q P PPP PP P P Q P
Sbjct: 1239 HHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPSLPPPPQQPP 1298
Query: 1645 NSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPP------PGPAPHHHPPPHPST 1698
Q S+ V P H H+ H P P P PG AP HP
Sbjct: 1299 PLPQLGSIPPPPASAPPVGPHRHFHA-----HGPVPGPQHYTLGRPGRAPRRGAGGHPQF 1353
Query: 1699 GLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPH-QGPPLFPSSAHPT 1757
G HQ ++P P P P H P H QGP F S HP
Sbjct: 1354 APHGRHPLHQ---PTSPLPLYSPAPQ---------------HPPAHKQGPKHFIFSHHPQ 1395
Query: 1758 VPPYPSQATHHTTLGPG-----PQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFC 1812
+ P A + PG P H S PH P+P PH P+ P P S
Sbjct: 1396 MMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIP---PH-----PSYPPLPPPSPHT 1447
Query: 1813 PHPGSVALPHGVQGPQQASPVPG 1835
PH S P GP AS PG
Sbjct: 1448 PH--SPLPPTSPHGPLHASGPPG 1468
Score = 67.8 bits (164), Expect = 9e-11
Identities = 68/233 (29%), Positives = 83/233 (35%), Gaps = 56/233 (24%)
Query: 1626 VPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPG 1685
+PPPPPPPP P + Q+P S+ + + G P PPPP G
Sbjct: 1180 MPPPPPPPP-PEEYKSQRPVSNSSSFLGSLFGSKRGKGP------------FQMPPPPTG 1226
Query: 1686 PAP-------------HHHPPPHPSTGL-------QGLQAQH-QHVVNSAPPPPPPPPPS 1724
A HHH H GL LQA H Q+ P PPP PP
Sbjct: 1227 QASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQ 1286
Query: 1725 SVLASGHHTTSAQALHHPPHQGPPL-------FPSSAHPTVPPYPSQATHHTTLGPGPQH 1777
+L PP Q PPL P ++ P V P+ H PGPQH
Sbjct: 1287 Q-----------PSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPV--PGPQH 1333
Query: 1778 QPSGTGPHCPLPVTGPHLQ--PQGPNSIPTPTASGFCPHPGSVALPHGVQGPQ 1828
G P G H Q P G + + PT+ P P QGP+
Sbjct: 1334 YTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPK 1386
Score = 63.2 bits (152), Expect = 2e-09
Identities = 67/240 (27%), Positives = 81/240 (33%), Gaps = 47/240 (19%)
Query: 1656 VGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPH--HHPPPHPSTGLQGLQAQHQHVVNS 1713
VG + + GS I S +PPPPPPP P + P + S+ L L +
Sbjct: 1159 VGSLDSTIEGSVISSPRPHQRMPPPPPPPPPEEYKSQRPVSNSSSFLGSLFGSKR---GK 1215
Query: 1714 APPPPPPPPPSSVLASGHHTTSAQALHHPPHQG--------------------------- 1746
P PPPP AS +S HH H G
Sbjct: 1216 GPFQMPPPPTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGP 1275
Query: 1747 ---PPLFPSSAHPTVPPYPSQATHHTTLG--PGPQHQPSGTGPHCPL----PVTGP-HLQ 1796
PP + P++PP P Q LG P P GPH PV GP H
Sbjct: 1276 GPAPPPYLPPQQPSLPPPPQQPPPLPQLGSIPPPPASAPPVGPHRHFHAHGPVPGPQHYT 1335
Query: 1797 PQGPNSIPTPTASG---FCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYH 1853
P P A G F PH G L SP P P H+ Q P F ++H
Sbjct: 1336 LGRPGRAPRRGAGGHPQFAPH-GRHPLHQPTSPLPLYSPAPQHPPAHK-QGPKHFIFSHH 1393
Score = 48.9 bits (115), Expect = 5e-05
Identities = 69/272 (25%), Positives = 97/272 (35%), Gaps = 37/272 (13%)
Query: 1405 SNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGY 1464
++++ A S +H H S LP +KL + + + P + P+ P Q
Sbjct: 1230 ASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQSKLQALHAQYCQGPGPAPPPYLPPQQPS 1289
Query: 1465 LSP----KPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFT 1520
L P PP QLGS P + +P VG P R+F+ A Q T G
Sbjct: 1290 LPPPPQQPPPLPQLGS-IPPPPASAPPVG-----PHRHFH--AHGPVPGPQHYTLGRPGR 1341
Query: 1521 QTPSGQSS-ATYSQFNQQSLNS-TAPPPPPPPPPSSSYYQNQQPS-ANFQNYNQLKGSLS 1577
G ++ + L+ T+P P P P Q P F ++ Q+ +
Sbjct: 1342 APRRGAGGHPQFAPHGRHPLHQPTSPLPLYSPAPQHPPAHKQGPKHFIFSHHPQMMPAAG 1401
Query: 1578 QQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPP--PPPPA 1635
GP PG G + P H Q+P H + +PP P PP P
Sbjct: 1402 A----AGGPGSRPPG--------GSYSHPHH---PQSPLSPH----SPIPPHPSYPPLPP 1442
Query: 1636 PGPHLVQQP-NSHQQHSVAHVVGPVHAVTPGS 1666
P PH P H H GP P S
Sbjct: 1443 PSPHTPHSPLPPTSPHGPLHASGPPGTANPPS 1474
>gi|24308073 protein tyrosine phosphatase, non-receptor type 23 [Homo
sapiens]
Length = 1636
Score = 90.1 bits (222), Expect = 2e-17
Identities = 133/500 (26%), Positives = 166/500 (33%), Gaps = 121/500 (24%)
Query: 1382 STVSASEAENGVHLKTELQQKQ------------LSNNNQALSKNHPPQTHVRNSSEQL- 1428
ST A EA L EL++K ++A+ PP+ +R+ +
Sbjct: 695 STCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPE-ELRSLPPDMV 753
Query: 1429 -SQKLPSV----PTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPS--QQLGSPYRPH 1481
+LP T LH PPSP P S+ P G L P S QL P P
Sbjct: 754 AGPRLPDTFLGSATPLHFPPSPF----PSSTGPGPHYLSGPLPPGTYSGPTQLIQPRAPG 809
Query: 1482 HSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNS 1541
P P P + P +P ++ Q G S+ Y
Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQ-----------HGVVSSPYV--------G 850
Query: 1542 TAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQAL---PGTTSQQT 1598
P PP PS+ P F SGP A+ P TT+ +
Sbjct: 851 VGPAPPVAGLPSA-------PPPQF-----------------SGPELAMAVRPATTTVDS 886
Query: 1599 VPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPP--PAPGPHLVQQPNSHQQHSVAHVV 1656
+ P H P NPT P PPPP P P P + P ++
Sbjct: 887 IQAP--IPSHTAPRPNPT-----------PAPPPPCFPVPPPQPLPTPYTY--------- 924
Query: 1657 GPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGL------QGLQAQHQHV 1710
P A P H ++G P P GP P HP PHPS Q L QH H+
Sbjct: 925 -PAGAKQPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQAFGPQPPQQPLPLQHPHL 983
Query: 1711 VNSAPPP--PPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHH 1768
P PP P G LH + GP P AH P+PS
Sbjct: 984 FPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALPFPSPGP-- 1041
Query: 1769 TTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQ 1828
P P H P GP P +P GP + P T G S PH V P
Sbjct: 1042 ----PQPPHPPLAYGP-------APSTRPMGPQAAPL-TIRGPSSAGQSTPSPHLVPSP- 1088
Query: 1829 QASPVPGQIPIH--RAQVPP 1846
SP PG +P A+ PP
Sbjct: 1089 APSPGPGPVPPRPPAAEPPP 1108
Score = 76.3 bits (186), Expect = 3e-13
Identities = 95/359 (26%), Positives = 121/359 (33%), Gaps = 49/359 (13%)
Query: 1520 TQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPP------SSSYYQNQQPSANFQNY--NQ 1571
TQ+ A Q + L PP P P P S + P ++ +
Sbjct: 693 TQSTCQAREAARQQLLDRELKKKPPPRPTAPKPLLPRREESEAVEAGDPPEELRSLPPDM 752
Query: 1572 LKGSLSQQTVFTSG-PNQALPGTTSQQTVPGHHVTPGHFLPS--QNPTIHHQTAAAVVPP 1628
+ G T S P P T PG H G P PT Q P
Sbjct: 753 VAGPRLPDTFLGSATPLHFPPSPFPSSTGPGPHYLSGPLPPGTYSGPT---QLIQPRAPG 809
Query: 1629 PPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAG--HHLPPPPPPPGP 1686
P P APGP L P + + P H V ++ A LP PPP
Sbjct: 810 PHAMPVAPGPALYPAPAYTPELGLVPRSSPQHGVVSSPYVGVGPAPPVAGLPSAPPPQFS 869
Query: 1687 APHHHPPPHP-STGLQGLQAQ-HQHVV---NSAPPPPPP----PPPSSVLASGHHTTSAQ 1737
P P +T + +QA H N P PPPP PPP + + A+
Sbjct: 870 GPELAMAVRPATTTVDSIQAPIPSHTAPRPNPTPAPPPPCFPVPPPQPLPTPYTYPAGAK 929
Query: 1738 ----ALHHPPHQGPPLFPS-----SAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPL 1788
A HH P FP+ P P+PSQA GP P P PL
Sbjct: 930 QPIPAQHHFSSGIPAGFPAPRIGPQPQPHPQPHPSQA-----FGPQP--------PQQPL 976
Query: 1789 PVTGPHL-QPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQ-QASPVPGQIPIHRAQVP 1845
P+ PHL PQ P +P + + P PG + P Q P +P H +P
Sbjct: 977 PLQHPHLFPPQAPGLLPPQSPYPYAPQPGVLGQPPPPLHTQLYPGPAQDPLPAHSGALP 1035
Score = 45.1 bits (105), Expect = 7e-04
Identities = 67/251 (26%), Positives = 87/251 (34%), Gaps = 50/251 (19%)
Query: 1312 KGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGK 1371
+ P+PS + +P P P P P P P + P IPAQ H
Sbjct: 888 QAPIPSHTAPRPNPTPAPPPPCFPVPPPQP--------LPTPYTYPAGAKQPIPAQHH-- 937
Query: 1372 IFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQK 1431
+ S + A ++ Q + HP Q + Q
Sbjct: 938 --------FSSGIPAG-----------FPAPRIGPQPQPHPQPHPSQAF---GPQPPQQP 975
Query: 1432 LPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPP---SQQLGSPYR---PHHSQS 1485
LP L P +P L PP+S P+ P Q G L PP +Q P + P HS +
Sbjct: 976 LPLQHPHLFPPQAPGL-LPPQSPYPYAP-QPGVLGQPPPPLHTQLYPGPAQDPLPAHSGA 1033
Query: 1486 ---PQVGTPQ-REPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNS 1541
P G PQ P + PA P Q A T G SSA S + + S
Sbjct: 1034 LPFPSPGPPQPPHPPLAYGPAPSTRPMGPQAA------PLTIRGPSSAGQSTPSPHLVPS 1087
Query: 1542 TAPPPPPPPPP 1552
AP P P P P
Sbjct: 1088 PAPSPGPGPVP 1098
Score = 33.9 bits (76), Expect = 1.5
Identities = 36/124 (29%), Positives = 46/124 (37%), Gaps = 26/124 (20%)
Query: 1628 PPPPPPPAPGPHLVQQPNSHQQHSVAHVVG---PVHAVT---------PGSHIHSQTAGH 1675
PPP P A + Q N Q S V+G P+ ++ P + S A
Sbjct: 1463 PPPCKPLASAS--ISQKNHLPQDSQDLVLGGDVPISSIQATIAKLSIRPPGGLESPVAS- 1519
Query: 1676 HLPPPPPPPG----------PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSS 1725
LP P PPG P P PPP S + Q + + V AP PP
Sbjct: 1520 -LPGPAEPPGLPPASLPESTPIPSSSPPPLSSPLPEAPQPKEEPPVPEAPSSGPPSSSLE 1578
Query: 1726 VLAS 1729
+LAS
Sbjct: 1579 LLAS 1582
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 87.0 bits (214), Expect = 2e-16
Identities = 92/318 (28%), Positives = 110/318 (34%), Gaps = 51/318 (16%)
Query: 1544 PPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHH 1603
PPPPPPPPP PSA +K S + S + AL + +
Sbjct: 637 PPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQS 696
Query: 1604 VTPGHFLPSQNPTIHHQTAAAVVPPPPP--PPPAPGPHLVQQPNSHQQHSVAHVVGPVHA 1661
V P +P VVPPPPP PPP PG + Q + S+ P
Sbjct: 697 VKPQILVPPNG----------VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAP--- 743
Query: 1662 VTPGSHIHS-QTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQ-----HVVNSAP 1715
P IH Q PP PPPP P P PP P L + A VV A
Sbjct: 744 -PPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAA 802
Query: 1716 PPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGP 1775
PP P PP PP + P FP+S P PP P TL P
Sbjct: 803 PPTPTPPV------------------PPAKKQPAFPASYIPPSPPTPPVPVPPPTL---P 841
Query: 1776 QHQ----PSGTGPHCPLPVTGPHLQPQGPNSIPTPTA---SGFCPHPGSVALPHGVQGPQ 1828
+ Q P P+P + Q P PTP A P P +VA
Sbjct: 842 KQQSFCAKPPPSPLSPVPSVVKQIASQFPPP-PTPPAMESQPLKPVPANVAPQSPPAVKA 900
Query: 1829 QASPVPGQIPIHRAQVPP 1846
+ P IP+ PP
Sbjct: 901 KPKWQPSSIPVPSPDFPP 918
Score = 80.5 bits (197), Expect = 1e-14
Identities = 120/522 (22%), Positives = 168/522 (32%), Gaps = 94/522 (18%)
Query: 1382 STVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHC 1441
S+V + + G L+ E + ++ + N+ + PP + + PS P
Sbjct: 574 SSVFSEAWKRGTQLE-ESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPP 632
Query: 1442 PPSPHLENPPKSSTPHTPVQH----GYLSP-----------KPPSQQLGSPYRPHHS--- 1483
PP P PP P P Q G +P + SQ G+ ++P
Sbjct: 633 PPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVM 692
Query: 1484 QSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQ------- 1536
QS V P P P T G+ Q + + QF+
Sbjct: 693 QSQSVKPQILVPPNGVVPPP---PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI 749
Query: 1537 ---QSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSG----PNQA 1589
Q + APP PPPPPP + Q P + + V T P
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809
Query: 1590 LPGTTSQQTVPGHHVTPGHF---LPSQNPTIHHQTAAAVVPPPPP--------------- 1631
+P Q P ++ P +P PT+ Q + PPP P
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQF 869
Query: 1632 PPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHS------------QTAGHHLPP 1679
PPP P + QP +VA P P S + PP
Sbjct: 870 PPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPP 929
Query: 1680 PPPPPGPAPHHHPPPHPS-----TGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTT 1734
PPP P PAP PPP S +G G + PPP P SS+
Sbjct: 930 PPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSI-------K 982
Query: 1735 SAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSG----TGPHCP--- 1787
S+ HP + P + S PP S + TL P G +G + P
Sbjct: 983 SSSGAEHPEPKRPSV-DSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVL 1041
Query: 1788 ----LPVTGPHLQPQGPNSI----PTPTASGFCPHPGSVALP 1821
+ P L +G +S+ P+ S F P P LP
Sbjct: 1042 QQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELP 1083
Score = 72.0 bits (175), Expect = 5e-12
Identities = 72/265 (27%), Positives = 90/265 (33%), Gaps = 73/265 (27%)
Query: 1627 PPPPPPPPAPGP---------------------HLVQQPNSHQQHSVAHVVGPVHAVTPG 1665
PPPPPPPP P P + + + QHS A P V
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694
Query: 1666 SHIHSQ---TAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQA----------------- 1705
+ Q +PPPPPPP PPP P + + L+
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPP-------PPPTPGSAMAQLKPAPCAPSLPQFSAPPPPL 747
Query: 1706 ---QHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYP 1762
Q QH+ APP PPPPPP QA PP + ++ TV P
Sbjct: 748 KIHQVQHITQVAPPTPPPPPPIPA------PLPPQA---PPKPLVTIPAPTSTKTVAPVV 798
Query: 1763 SQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPT-PTASGFCPHPGSVALP 1821
+QA T P P + P +P + P P P PT P FC P
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPSPP--TPPVPVPPPTLPKQQSFCAKP------ 850
Query: 1822 HGVQGPQQASPVPGQIPIHRAQVPP 1846
P SPVP + +Q PP
Sbjct: 851 ----PPSPLSPVPSVVKQIASQFPP 871
Score = 62.0 bits (149), Expect = 5e-09
Identities = 130/577 (22%), Positives = 184/577 (31%), Gaps = 128/577 (22%)
Query: 1325 PDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTV 1384
P P+ P T ++ PSP PP P P +P+Q+ +
Sbjct: 611 PQPKIVTPYTASQ-PSPPLPPPPPPPPPPPPPPPPPPPPLPSQS-------------APS 656
Query: 1385 SASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPS 1444
+ S A V T + + S ++ AL K PP V S Q L VP PP
Sbjct: 657 AGSAAPMFVKYSTITRLQNASQHSGALFK--PPTPPVMQSQSVKPQIL--VPPNGVVPPP 712
Query: 1445 PHLENPPKSST--------PHTPVQHGYLSPKPPSQ--------QLGSPYRPHHSQSPQV 1488
P PP + P P + +P PP + Q+ P P P
Sbjct: 713 PPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAP 772
Query: 1489 GTPQREPQRNFYPAAQNLPANTQQATSGTLFTQ------TPSGQSSATYSQFNQQSLNST 1542
PQ P+ +PA T T + TQ TP + F + +
Sbjct: 773 LPPQAPPK-----PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPS 827
Query: 1543 APPPPPPPPPSS-----SYYQNQQPSANFQNYNQLKGSLSQ------QTVFTSGPNQALP 1591
P PP P PP + S+ PS + +K SQ S P + +P
Sbjct: 828 PPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVP 887
Query: 1592 GTTSQQTVPGHHVTPGHFLPSQNPTIHHQ------TAAAVVPPPPP-----PPPAPGPHL 1640
+ Q+ P P + PS P ++ V PPPPP PPP P P
Sbjct: 888 ANVAPQSPPAVKAKP-KWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTA 946
Query: 1641 VQQPNSH-----QQHSVAHVVGPVHAVTP--GSHIHSQTAGHH----------------- 1676
P+ + + G TP S I S + H
Sbjct: 947 SPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTP 1006
Query: 1677 -----------LPPPPPPPGPAPHHHPPPH-PSTGLQG--------LQAQHQHVVNSAPP 1716
LPPP PP P + + P QG L + + V P
Sbjct: 1007 PAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPS 1066
Query: 1717 PP-----PPPPPSS----------VLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPY 1761
PP PPPPP + + SG+ + ++ P Q + A P P
Sbjct: 1067 PPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPK 1126
Query: 1762 PSQATHHTTLGPGPQHQPSGTGPHCPL-PVTGPHLQP 1797
+ +T T Q + P P P + +QP
Sbjct: 1127 RNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQP 1163
Score = 57.8 bits (138), Expect = 1e-07
Identities = 71/279 (25%), Positives = 82/279 (29%), Gaps = 101/279 (36%)
Query: 1624 AVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPP 1683
++VPP P P P+ QP+ LPPPPPP
Sbjct: 604 SLVPPLSPQPKIVTPYTASQPSPP-----------------------------LPPPPPP 634
Query: 1684 PGPAPHHHPPPHPSTGLQG-------------------LQAQHQH--------------- 1709
P P P PPP P Q LQ QH
Sbjct: 635 PPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQS 694
Query: 1710 -------------VVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP 1756
VV PPPPPPP P S +A A +L P PP
Sbjct: 695 QSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSL--PQFSAPP-------- 744
Query: 1757 TVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTAS------- 1809
PP H T P P P PLP P P+ +IP PT++
Sbjct: 745 --PPLKIHQVQHITQVAPPTPPPPPPIP-APLP---PQAPPKPLVTIPAPTSTKTVAPVV 798
Query: 1810 --GFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPP 1846
P P P Q AS +P P VPP
Sbjct: 799 TQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPP 837
Score = 53.9 bits (128), Expect = 1e-06
Identities = 122/536 (22%), Positives = 167/536 (31%), Gaps = 94/536 (17%)
Query: 1296 QSSPSSHSNHIPQLQAKGPVPSFSELME---------DPDPENPEPTTTNECPSP----- 1341
Q P+ + +PQ A P ++ P P P P P P
Sbjct: 727 QLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIP 786
Query: 1342 -DTSQNTCKS--------------PPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSA 1386
TS T PP +P P S IP T P P T+
Sbjct: 787 APTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPP----TPPVPVPPPTLPK 842
Query: 1387 SEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPH 1446
++ + L S Q S+ PP T SQ L VP + P
Sbjct: 843 QQSFCAKPPPSPLSPVP-SVVKQIASQFPPPPT----PPAMESQPLKPVPANVAPQSPPA 897
Query: 1447 LENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNL 1506
++ PK PV P PP L P P SP P P P A
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPP---PSPVPAPPPPPP-----PTASPT 949
Query: 1507 PANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPS-SSYYQNQQPSAN 1565
P + T T +P G+ Q N +S+ P P PS S P A
Sbjct: 950 PDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAE 1009
Query: 1566 FQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF----LPSQNPTIHHQT 1621
GS S++T+ P A P + + G ++ PG + ++ P + +
Sbjct: 1010 -------SGSPSKETL----PPPAAPPKPGKLNLSGVNL-PGVLQQGCVSAKAPVLSGRG 1057
Query: 1622 AAAVVPPPPP------PPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGH 1675
+VV P P PPP P L P + V V P S+ +
Sbjct: 1058 KDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVK 1117
Query: 1676 HLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSV------LAS 1729
PPP P + ST L + Q + + P P P SS+ LA
Sbjct: 1118 KAPPPT---------RPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLAD 1168
Query: 1730 GHHTTSAQALHHPPHQGPPLFPSSAHPTV--------PPYPSQATHHTTLGPGPQH 1777
+ T +++ H S A PT PP P + G G H
Sbjct: 1169 LNRTLQRKSITR--HGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSH 1222
Score = 49.7 bits (117), Expect = 3e-05
Identities = 102/412 (24%), Positives = 138/412 (33%), Gaps = 86/412 (20%)
Query: 1291 SPSHVQSSPSSHSNHIPQLQAKGPVPS------FSELMEDPDPENPEPTTTNECPSPDTS 1344
SP V++ P + IP P P F P P P P P+PD S
Sbjct: 894 SPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKS 953
Query: 1345 QNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQL 1404
+ K K SK SPG P P PQ +S++ +S E + +
Sbjct: 954 GSPGK---KTSKTSSPGGKKP---------PPTPQRNSSIKSSSG-------AEHPEPKR 994
Query: 1405 SNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGY 1464
+ + +SK PP S E L PP P N + P +Q G
Sbjct: 995 PSVDSLVSKFTPPAESGSPSKETLPPPA--------APPKPGKLNLSGVNLPGV-LQQGC 1045
Query: 1465 LSPKPP-------SQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGT 1517
+S K P + P P S P P E + P +PA TS
Sbjct: 1046 VSAKAPVLSGRGKDSVVEFPSPPSDSDFP---PPPPETELPLPPI--EIPAVFSGNTSPK 1100
Query: 1518 LFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQ---NQQPSANF---QNYNQ 1571
+ P Q Q+++ S+ PP P S+ Q ++QP+ Q
Sbjct: 1101 VAVVNPQPQ------QWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTS 1154
Query: 1572 LKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPP 1631
K SLS Q F + N+ L Q+ H + + PT A +PPPPP
Sbjct: 1155 PKSSLSVQPGFLADLNRTL-----QRKSITRHGSLSSRMSRAEPTATMDDMA--LPPPPP 1207
Query: 1632 PPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPP 1683
+ S QQ A GSHI PPP PP
Sbjct: 1208 -----------ELLSDQQ----------KAGYGGSHISGYATLRRGPPPAPP 1238
>gi|42544130 splicing factor 1 isoform 1 [Homo sapiens]
Length = 639
Score = 86.7 bits (213), Expect = 2e-16
Identities = 91/303 (30%), Positives = 112/303 (36%), Gaps = 66/303 (21%)
Query: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602
AP PPPP S Q++ P N SGP+++ P PG
Sbjct: 348 APANNPPPPSLMSTTQSRPPWMN------------------SGPSESRPYHGMHGGGPGG 389
Query: 1603 HVTPGHFLPSQNPTI------HHQTAAAVVPPPP-----PPPPAPGPHLVQQPNSHQQHS 1651
H P P++ H PPPP PPP GPH P H
Sbjct: 390 PGGGPHSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPH---PPGHHGPPP 446
Query: 1652 VAHVVGPVHAVTP-GSHIHSQTAGHHLPPPPP-----PPGPAPHHHPPPHPSTGLQGLQA 1705
+ +G TP GS ++ G + PPPP PP P P PPP PS L Q
Sbjct: 447 MDQYLGS----TPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQ 502
Query: 1706 QHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP-TVPPYPSQ 1764
Q Q PPPPPPPSS +AS + P Q +SA ++PP+ Q
Sbjct: 503 QQQQ-------PPPPPPPSSSMAS--------STPLPWQQNTTTTTTSAGTGSIPPWQQQ 547
Query: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGV 1824
PQ Q G PLP P +QP P P P P PGS + +
Sbjct: 548 QAAAAASPGAPQMQ--GNPTMVPLP---PGVQPPLPPGAPPPPPP---PPPGSAGMMYAP 599
Query: 1825 QGP 1827
P
Sbjct: 600 PPP 602
Score = 71.6 bits (174), Expect = 7e-12
Identities = 83/298 (27%), Positives = 99/298 (33%), Gaps = 92/298 (30%)
Query: 1442 PPSPHLENPPK--SSTPHTPVQHGYLSPKPPSQQLGSP------YRPHHSQS----PQVG 1489
PP P ++ PP + PH P HG P P Q LGS YR H + P +G
Sbjct: 420 PPPPWMQPPPPPMNQGPHPPGHHG---PPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMG 476
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
P P+ Q P PSG Q Q PPPP
Sbjct: 477 MMPPPPPP---PSGQPPPP--------------PSGPLPPWQQQQQQ---------PPPP 510
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF 1609
PPPSSS + L + T TS ++P QQ +PG
Sbjct: 511 PPPSSSMASS----------TPLPWQQNTTTTTTSAGTGSIPPWQQQQAAAA--ASPGAP 558
Query: 1610 LPSQNPTIHHQTAAAVVPPPP--PPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSH 1667
NPT+ P PP PPPP P P PGS
Sbjct: 559 QMQGNPTMVPLPPGVQPPLPPGAPPPPPPPP-------------------------PGS- 592
Query: 1668 IHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSS 1725
AG PPPPPP P + G+ G+ PP PPPPPP +
Sbjct: 593 -----AGMMYAPPPPPPPPMDPSNFVTMMGMGVAGMPPF------GMPPAPPPPPPQN 639
Score = 61.2 bits (147), Expect = 9e-09
Identities = 70/240 (29%), Positives = 78/240 (32%), Gaps = 58/240 (24%)
Query: 1621 TAAAVVPPPPPP---PPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHL 1677
T A P P P PP P Q +S P H + G
Sbjct: 338 TPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGG----------- 386
Query: 1678 PPPPPPPGPAPHHHPPPHPSTGLQGLQAQH--QHVVNSAPPP--PPPPPPSSVLASGHHT 1733
P PG PH P P PS L G H QH N PPP PPPPP +
Sbjct: 387 ---PGGPGGGPHSFPHPLPS--LTGGHGGHPMQHNPNGPPPPWMQPPPPPMN-------- 433
Query: 1734 TSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQ--HQPSGTGPHCPLPVT 1791
Q H P H GPP Q T +G G HQ G P P+ +
Sbjct: 434 ---QGPHPPGHHGPPPM------------DQYLGSTPVGSGVYRLHQGKGMMPPPPMGMM 478
Query: 1792 GPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNN 1851
P P P SG P P S LP Q QQ P P + P +Q N
Sbjct: 479 PP----------PPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQN 528
Score = 58.9 bits (141), Expect = 4e-08
Identities = 92/410 (22%), Positives = 131/410 (31%), Gaps = 73/410 (17%)
Query: 1382 STVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHC 1441
+T ++ H+ ++ + ++ + A K + ++ +E +P+
Sbjct: 275 NTTVCTKCGGAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGSTSG 334
Query: 1442 PPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYP 1501
P + L + P+ + P +P PPS + RP S G + P +
Sbjct: 335 PATTPLASAPRPAAPAN-------NPPPPSLMSTTQSRPPWMNS---GPSESRPYHGMHG 384
Query: 1502 AAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPP---PPPPPSSSYYQ 1558
P + L + T G + N PPPP PPPPP
Sbjct: 385 GGPGGPGGGPHSFPHPLPSLT-GGHGG------HPMQHNPNGPPPPWMQPPPPP-----M 432
Query: 1559 NQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIH 1618
NQ P + T SG + G P + P PS P
Sbjct: 433 NQGPHPPGHHGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPP-- 490
Query: 1619 HQTAAAVVPP-------PPPPPPAPGPHLVQQPNSHQQHSVAHVVGP------------- 1658
+ +PP PPPPPP P QQ++
Sbjct: 491 -PPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLPWQQNTTTTTTSAGTGSIPPWQQQQA 549
Query: 1659 VHAVTPGS-HIHSQTAGHHLPP---PPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
A +PG+ + LPP PP PPG P PPP P G G+
Sbjct: 550 AAAASPGAPQMQGNPTMVPLPPGVQPPLPPGAPP---PPPPPPPGSAGMMYA-------- 598
Query: 1715 PPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
PPPPPPPP S T + P G P P PP P Q
Sbjct: 599 -PPPPPPPPMD--PSNFVTMMGMGVAGMPPFGMP-------PAPPPPPPQ 638
Score = 34.3 bits (77), Expect = 1.2
Identities = 71/368 (19%), Positives = 105/368 (28%), Gaps = 83/368 (22%)
Query: 1218 PTPATVYNATSEETSN--NCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDH 1275
P PA+V + + T+ + P A A+ P + T + + + H
Sbjct: 324 PVPASVGSTSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMH 383
Query: 1276 RKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTT 1335
G P P + S H H Q GP P + + P + P P
Sbjct: 384 GGGPGGPGGGP--HSFPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGH 441
Query: 1336 NECPSPDTSQNTCK---------------------------SPPKMSKPGSPGSVIPAQA 1368
+ P D + PP P P +P
Sbjct: 442 HGPPPMDQYLGSTPVGSGVYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQ 501
Query: 1369 HGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPP--QTHVRNSSE 1426
+ P P S++++S QQ + A + + PP Q ++
Sbjct: 502 QQQQQPPPPPPPSSSMASSTP-------LPWQQNTTTTTTSAGTGSIPPWQQQQAAAAAS 554
Query: 1427 QLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSP 1486
+ ++ PT + PP PP + P P PP G Y P P
Sbjct: 555 PGAPQMQGNPTMVPLPPGVQPPLPPGAPPP---------PPPPPPGSAGMMYAP-----P 600
Query: 1487 QVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPP 1546
P +P NF T G A F PP
Sbjct: 601 PPPPPPMDPS-NFV---------------------TMMGMGVAGMPPFGM-------PPA 631
Query: 1547 PPPPPPSS 1554
PPPPPP +
Sbjct: 632 PPPPPPQN 639
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 85.5 bits (210), Expect = 4e-16
Identities = 103/352 (29%), Positives = 122/352 (34%), Gaps = 73/352 (20%)
Query: 1543 APPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGH 1602
APPPPPPPP QQP + L+ L Q P Q + +T P
Sbjct: 319 APPPPPPPP-------QQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLET-PRM 370
Query: 1603 HVTPGHFLPSQNPTIH---HQTAAAV-------VPPPPPPPPAPGPHLVQQPNSHQQHSV 1652
+TP P Q IH H V +P P P PA GP P QH
Sbjct: 371 MMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQH-- 428
Query: 1653 AHVVGPVHAVTPGSHIHSQTAGHHLP------PPPPPPGPAPHHHPPPHPSTGLQGLQAQ 1706
TPG +S + LP PPPP P G+ G
Sbjct: 429 ----------TPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFF-------LGVSGEPRF 471
Query: 1707 HQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGP--------PLFPSS--AHP 1756
H+ PPPPPPP ++L S H + L GP P+FP P
Sbjct: 472 PSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPF-TQPGPAFNQQGQQPVFPRERPVRP 530
Query: 1757 TV-PPYPSQATHHTTLGPG------PQHQPSGTGPHCPLPVTGPHLQP--QGPNSIPTPT 1807
+ PP P H + G P QP GP P T H QP QGP P P
Sbjct: 531 ALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPT--HTQPNLQGPLHPPLPP 588
Query: 1808 ASGFCPH------PGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYH 1853
P P PH Q P Q P P H Q PP Q+++H
Sbjct: 589 PHQPQPQQPQQQPPPQHQPPH--QPPHQPPPQHQPPPQHPPQHPPQHQHHHH 638
Score = 75.1 bits (183), Expect = 6e-13
Identities = 91/334 (27%), Positives = 116/334 (34%), Gaps = 35/334 (10%)
Query: 1416 PPQ-THVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLS-PKPPSQQ 1473
PPQ H+ E + P P + H+ NP T TPVQ L P P
Sbjct: 355 PPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHI-NPHFKGTVVTPVQVPLLPVPSQPRPA 413
Query: 1474 LGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQ 1533
+G P + PQ TP P N + LP Q + P + +
Sbjct: 414 VGPQRFPGPPEFPQ-HTPGPVP--NSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPR 470
Query: 1534 FNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGT 1593
F PPPPPPPP+ + P+ + + Q + +QQ G P
Sbjct: 471 FPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQ-----GQQPVFPRE 525
Query: 1594 TSQQTVPGHHVTPGHFLPSQNPTIHH-QTAAAVVPP--PPPPPPAPGPHLVQQPNSHQQH 1650
V P P +H Q +A P PP P PGP P H
Sbjct: 526 RP--------VRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPT----H 573
Query: 1651 SVAHVVGPVHAVTPGSHI------HSQTAGHHLPPPPPPPGPAPHHH-PPPHPSTGLQGL 1703
+ ++ GP+H P H Q H PP PP P P H PP HP
Sbjct: 574 TQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQ--HPP 631
Query: 1704 QAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQ 1737
Q QH H + PPPP P S H +AQ
Sbjct: 632 QHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQ 665
Score = 50.4 bits (119), Expect = 2e-05
Identities = 43/145 (29%), Positives = 50/145 (34%), Gaps = 24/145 (16%)
Query: 1710 VVNSAPPPPPPPPPSSVLAS---------------GHHTTSAQALHHPPHQGPPLFPSSA 1754
VV APPPPPPPP + S HH + Q +H PP P +
Sbjct: 315 VVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTP 374
Query: 1755 HPTVPPYPSQA---THHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGF 1811
P P P H P P P P P GP P GP P T
Sbjct: 375 PPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFP-GPPEFPQHTPG-- 431
Query: 1812 CPHPGSVALPH--GVQGPQQASPVP 1834
P P S + P +Q +A P P
Sbjct: 432 -PVPNSFSQPPRLPLQDQWRAPPPP 455
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 84.3 bits (207), Expect = 1e-15
Identities = 85/251 (33%), Positives = 90/251 (35%), Gaps = 42/251 (16%)
Query: 1591 PGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQH 1650
PG P P H Q P Q PPP PPP P PH QQP Q
Sbjct: 49 PGPGQSGPKPPIPPPPPHQQQQQPPP---QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQD 105
Query: 1651 SVAHVV--GPVHAVTPGSHIHSQTAGHHLPPP----PPPPGPAPHHHPPPHPSTGLQGLQ 1704
S VV GP A GS + ++ PP PP GP P PPP
Sbjct: 106 SSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPP---------- 155
Query: 1705 AQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
V SAPP PPP P S SG TT PP G P P +A P P P Q
Sbjct: 156 -----AVTSAPPGAPPPTPPS---SGVPTT-------PPQAGGPPPPPAAVPGPGPGPKQ 200
Query: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGV 1824
GPGP G P P P GP L G + P P G P G P
Sbjct: 201 -------GPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKP-PHRGGGEPRGGRQHHPPYH 252
Query: 1825 QGPQQASPVPG 1835
Q Q P G
Sbjct: 253 QQHHQGPPPGG 263
Score = 54.7 bits (130), Expect = 8e-07
Identities = 74/274 (27%), Positives = 81/274 (29%), Gaps = 64/274 (23%)
Query: 1451 PKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANT 1510
P S P P+ P PP QQ +P Q P P +P + P Q P
Sbjct: 51 PGQSGPKPPIP-----PPPPHQQ---QQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPP 102
Query: 1511 QQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYN 1570
Q +S + Q P + S PP PP S P A
Sbjct: 103 PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPA------ 156
Query: 1571 QLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPP 1630
TS P A P T VP TP A PPPP
Sbjct: 157 -----------VTSAPPGAPPPTPPSSGVP---TTP--------------PQAGGPPPPP 188
Query: 1631 PPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAP-- 1688
P PGP Q P GP PG T G H P PP G P
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKMPGGP----KPGGGPGLSTPGGH-PKPPHRGGGEPRG 243
Query: 1689 --HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPP 1720
HHPP H Q HQ PPP P
Sbjct: 244 GRQHHPPYH--------QQHHQ-----GPPPGGP 264
Score = 51.2 bits (121), Expect = 9e-06
Identities = 52/180 (28%), Positives = 57/180 (31%), Gaps = 47/180 (26%)
Query: 1674 GHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHT 1733
G P PP PP PPPH Q Q Q PPP PPP
Sbjct: 52 GQSGPKPPIPP-------PPPH--------QQQQQ-------PPPQQPPPQQP------- 82
Query: 1734 TSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGP 1793
PPHQ PP P PP P Q + + GP P G G P + P
Sbjct: 83 --------PPHQPPP-HPQPHQQQQPPPPPQDSSKPVVAQGPGPAP-GVGSAPPASSSAP 132
Query: 1794 HLQP--------QGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVP 1845
P GP PTP + PG+ G P G P A VP
Sbjct: 133 PATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVP 192
Score = 47.0 bits (110), Expect = 2e-04
Identities = 49/166 (29%), Positives = 52/166 (31%), Gaps = 30/166 (18%)
Query: 1675 HHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTT 1734
H PPP G + P P G G + PP PPPPP
Sbjct: 29 HDFRSPPPGMG-LNQNRGPMGPGPGQSGPK-----------PPIPPPPPHQ--------- 67
Query: 1735 SAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPH 1794
Q PP Q PP P P P P Q P PQ P P G
Sbjct: 68 --QQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPP---PPPQDSSKPVVAQGPGPAPGVG 122
Query: 1795 LQPQGPNSIP--TPTASGFCPHPGSVALPHGVQGPQQASPVPGQIP 1838
P +S P TP SG PGS P P S PG P
Sbjct: 123 SAPPASSSAPPATPPTSG--APPGSGPGPTPTPPPAVTSAPPGAPP 166
Score = 37.7 bits (86), Expect = 0.11
Identities = 48/186 (25%), Positives = 60/186 (32%), Gaps = 31/186 (16%)
Query: 1313 GPVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKI 1372
GP P S P P P P + P Q + PP P P Q H +
Sbjct: 48 GPGPGQS----GPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHP------QPHQQQ 97
Query: 1373 FTKPDPQWDSTVSASEAEN---GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLS 1429
P PQ S ++ GV + S + PP T + + S
Sbjct: 98 QPPPPPQDSSKPVVAQGPGPAPGV------------GSAPPASSSAPPATPPTSGAPPGS 145
Query: 1430 QKLPSV---PTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSP 1486
P+ P PP PP S P TP Q G P PP + P P Q P
Sbjct: 146 GPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAG--GPPPPPAAVPGP-GPGPKQGP 202
Query: 1487 QVGTPQ 1492
G P+
Sbjct: 203 GPGGPK 208
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 83.2 bits (204), Expect = 2e-15
Identities = 180/720 (25%), Positives = 242/720 (33%), Gaps = 126/720 (17%)
Query: 1148 PQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGE 1207
P+ P + E ++ + S TE P P A G L SS+
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS---- 245
Query: 1208 QVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQ 1267
+ PL +PA S ++ P A S+ +Q V R+ +
Sbjct: 246 ------ATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 1268 RALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDP 1327
LS SP + SPS ++ P P A P+P+ L P
Sbjct: 295 ALGPLSS----------SPLATPSPSGTKARPVP-----PPDNAATPLPA--TLPPSPPL 337
Query: 1328 ENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVI--PAQAHGKIFTKPDPQWDSTVS 1385
P P PS S T SPP +P S+ P QA + T P Q +++
Sbjct: 338 ATPLPLAPPS-PSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLT 396
Query: 1386 ASEAE--------NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPT 1437
+ + + + T L L + L+ + P QT Q S PS P
Sbjct: 397 SPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMS-PRQT-------QASLTSPSRPA 448
Query: 1438 KLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQR 1497
P SP L+ P S P +P LSP L SP H Q
Sbjct: 449 STP-PDSPPLQAP--LSLPASPPLQTSLSPAV--SPLSSPLTIHPLQ------------- 490
Query: 1498 NFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPP----PPPPPPPS 1553
A +L +++ QA +L QSS + T PP P PPP
Sbjct: 491 ----ALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPL 546
Query: 1554 SSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPG--TTSQQTVPGHHVTPGHFLP 1611
Q SA + L P QA P TT P TP P
Sbjct: 547 ------QTASAPLTTPH-----LETPPCPAPCPLQAPPSPLTTPPPETPSSIATP----P 591
Query: 1612 SQNPTIHHQTAAAVVPPPP------PPPPAPGPHLVQQP-NSHQQHSVAHVVGPVHAVTP 1664
Q P +P PP PPP AP P L P + + + P+ TP
Sbjct: 592 PQAPPALASPPLQGLPSPPLSPLATPPPQAP-PXLALPPLQAPPSPPASPPLSPL--ATP 648
Query: 1665 GSHIHSQTAGHHLP----PPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPP 1720
+ A H L PPP PP AP P P + +Q + + P PP
Sbjct: 649 SPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPP 708
Query: 1721 PPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHP-TVPPY-PSQATHHTTLGPGPQHQ 1778
PP+S S T PP Q PP P +A P VPP P+ + P P+
Sbjct: 709 SPPASPPMSPSAT--------PPPQAPP--PLAAPPLQVPPSPPASPPMSPSATPPPRVP 758
Query: 1779 PSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIP 1838
P P +P + P P P + P P A P ++A P P + PGQ P
Sbjct: 759 PLLAAPPLQVPPSPPASLPMSPLAKPPPQA------PPALATPPLQALPSPPASFPGQAP 812
Score = 80.9 bits (198), Expect = 1e-14
Identities = 141/584 (24%), Positives = 195/584 (33%), Gaps = 118/584 (20%)
Query: 1292 PSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNE--------CPSPDT 1343
P SS +SHS P P + P + P + T P P
Sbjct: 488 PLQALSSLASHSPQAPLSSLIMPPLETQSSLAPPSLQTPPASLTTPPLENLPSLAPPPLQ 547
Query: 1344 SQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQ 1403
+ + + P + P P P QA T P P+ S+++
Sbjct: 548 TASAPLTTPHLETPPCPAPC-PLQAPPSPLTTPPPETPSSIATP---------------- 590
Query: 1404 LSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVP-TKLHCPPS---PHLENPPKSSTPHTP 1459
PPQ +S L Q LPS P + L PP P L PP + P P
Sbjct: 591 ------------PPQAPPALASPPL-QGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPP 637
Query: 1460 VQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLF 1519
PS Q + H Q+P P Q F P PA+ + S T
Sbjct: 638 ASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSP-----PASPPVSPSATPP 692
Query: 1520 TQTPSGQSSATY----SQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGS 1575
+Q P ++ S ++ +A PPP PPP ++ PS
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSP----------- 741
Query: 1576 LSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPP--- 1632
+ P + P T VP P +P P + A PP PP
Sbjct: 742 -------PASPPMS-PSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALA 793
Query: 1633 -PPA---PGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGP-- 1686
PP P P + S + + P+ TP A L PP PP
Sbjct: 794 TPPLQALPSPPASFPGQAPFSPSASLPMSPL--ATPPPQAPPVLAAPLLQVPPSPPASPT 851
Query: 1687 --APHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPP---PSSVLA----SGHHTTSAQ 1737
AP P P P T + G + + P PPPPP PSS L+ +GH +++
Sbjct: 852 LQAPRRPPTPGPDTSVSG-----PRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATS 906
Query: 1738 ALHH-PPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQ 1796
+ P ++A P PP A H GP PL G
Sbjct: 907 TPEELRGYDSGPEGGAAASP--PPDAELAACHPAAW--------SRGPAPPLAFRG---A 953
Query: 1797 PQGPNSIPTPTASGFCPHPGS---VALPHGVQGPQQASPVPGQI 1837
P P +P P A+G PGS + + +GP+ A+P PG +
Sbjct: 954 PGAP--LPWPPATG----PGSADGLCTIYETEGPESATPAPGAL 991
Score = 62.0 bits (149), Expect = 5e-09
Identities = 124/479 (25%), Positives = 162/479 (33%), Gaps = 99/479 (20%)
Query: 1397 TELQQKQLSNNNQALSKNHPPQTHVRNSS-----EQLSQKLPSVPTKLHCPPSPHLENPP 1451
TE +K +S+ ++ + P R S+ S+ L S T L SP P
Sbjct: 202 TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS---SPARSGPS 258
Query: 1452 KSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQ 1511
TP P PKP Q P PQV P+++ P + + A
Sbjct: 259 ARGTPRAPAHPS--QPKPKGLQALRP--------PQVTPPRKDAAPALGPLSSSPLATP- 307
Query: 1512 QATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPP--------PPPPSSSYYQNQQPS 1563
+ SGT P ++AT L +T PP PP PP PS+ PS
Sbjct: 308 -SPSGTKARPVPPPDNAAT-------PLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 1564 ANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAA 1623
+Q S+ T+ P QA P S QT+P P Q P H T+
Sbjct: 360 PPATPPSQAPPSM------TTPPMQAPP---SLQTIP----------PIQVP--HSLTSP 398
Query: 1624 AVVPPPPP-------------PPPAPGPH--LVQQPNSHQQHSVAHVVGPVHAVTPGSHI 1668
++ PP P P H L P Q A + P +
Sbjct: 399 SLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQ----ASLTSPSRPASTPPDS 454
Query: 1669 HSQTAGHHLPPPPP-PPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVL 1727
A LP PP +P P P T + LQA ++S P P SS++
Sbjct: 455 PPLQAPLSLPASPPLQTSLSPAVSPLSSPLT-IHPLQA-----LSSLASHSPQAPLSSLI 508
Query: 1728 ASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCP 1787
T S+ A P Q PP S P + PS A P P P CP
Sbjct: 509 MPPLETQSSLA--PPSLQTPPA--SLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCP 564
Query: 1788 LPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPP 1846
P P P P + P P P S+A P P QA P P+ PP
Sbjct: 565 APC--PLQAPPSPLTTPPPET------PSSIATP-----PPQAPPALASPPLQGLPSPP 610
>gi|110349788 absent, small, or homeotic 1-like [Homo sapiens]
Length = 2964
Score = 82.0 bits (201), Expect = 5e-15
Identities = 38/72 (52%), Positives = 48/72 (66%), Gaps = 3/72 (4%)
Query: 101 SSATTISTSEDG-SYGTDVTRCICGFTHDDGYMICCDKCSVWQHIDCMGIDRQHIPDTYL 159
SS T++S E+G DV RCICG D+G MI CDKC VWQH DCMG++ + YL
Sbjct: 2562 SSETSVSEKENGHEKDDDVIRCICGLYKDEGLMIQCDKCMVWQHCDCMGVNSD--VEHYL 2619
Query: 160 CERCQPRNLDKE 171
CE+C PR +D+E
Sbjct: 2620 CEQCDPRPVDRE 2631
Score = 62.8 bits (151), Expect = 3e-09
Identities = 47/205 (22%), Positives = 91/205 (44%), Gaps = 4/205 (1%)
Query: 343 LKSAKDLPPDALIIEYRGKFMLREQFEANGYFFKRPYPFVLFYSKFHGLEMCVDARTFGN 402
+++ + L IIEY G+ + ++F ++ + Y M +D+ GN
Sbjct: 2154 IRTKEPLKAGQFIIEYLGEVVSEQEFRNR--MIEQYHNHSDHYCLNLDSGMVIDSYRMGN 2211
Query: 403 EARFIRRSCTPNAEVRHEIQDGTIHLYIYSIHSIPKGTEITIAFDFDYGNCKYKVDCACL 462
EARFI SC PN E++ +G + +Y++ +P GTE+T ++F N + + C C
Sbjct: 2212 EARFINHSCDPNCEMQKWSVNGVYRIGLYALKDMPAGTELTYDYNFHSFNVEKQQLCKCG 2271
Query: 463 KENPECPVLKRSSESMENINSGYETRRKKGKKDKDISKEKDTQNQNITLDCEGTTNKMKS 522
E ++ S+ + + S ++ K SKEK + + +
Sbjct: 2272 FEKCR-GIIGGKSQRVNGLTSSKNSQPMATHKKSGRSKEKRKSKHKLKKRRGHLSEEPSE 2330
Query: 523 PETKQRKLSP-LRLSVSNNQEPDFI 546
+L+P L++ +N+E +F+
Sbjct: 2331 NINTPTRLTPQLQMKPMSNRERNFV 2355
Score = 35.8 bits (81), Expect = 0.40
Identities = 42/145 (28%), Positives = 57/145 (39%), Gaps = 23/145 (15%)
Query: 1263 ERSYQRALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHI-------PQLQAKGPV 1315
ER+ Q L S DK S S +CSP+ +SS S S+ + P+L A G
Sbjct: 1654 ERAVQ-TLAGSQPTSDKPSQRPSESTNCSPTRKRSSSESTSSTVNGVPSRSPRLVASGDD 1712
Query: 1316 PSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFT- 1374
S L E+ EP S D T +PP S P ++H K T
Sbjct: 1713 SVDSLLQRMVQNEDQEPME----KSIDAVIATASAPPSSS---------PGRSHSKDRTL 1759
Query: 1375 -KPDPQWDSTVSASEAENGVHLKTE 1398
KPD V++ N + L +E
Sbjct: 1760 GKPDSLLVPAVTSDSCNNSISLLSE 1784
Score = 33.5 bits (75), Expect = 2.0
Identities = 30/105 (28%), Positives = 39/105 (37%), Gaps = 19/105 (18%)
Query: 1675 HHLPPPPPPPGPAPHHHPP--PHPSTGLQ-GLQAQHQHVVNSAPPPPPPP-----PPSSV 1726
H L P G P + P P P T GL ++ PPPP P PP S
Sbjct: 1367 HSLSFPLSSTGFYPSYGMPYSPSPLTAAPIGLGYYGRYPPTLYPPPPSPSFTTPLPPPSY 1426
Query: 1727 LASGHHTTSAQALHHPPHQ-----------GPPLFPSSAHPTVPP 1760
+ +GH + H H+ PL S +P+VPP
Sbjct: 1427 MHAGHLLLNPAKYHKKKHKLLRQEAFLTTSRTPLLSMSTYPSVPP 1471
>gi|150417989 cyclin K isoform 1 [Homo sapiens]
Length = 580
Score = 80.9 bits (198), Expect = 1e-14
Identities = 92/350 (26%), Positives = 122/350 (34%), Gaps = 71/350 (20%)
Query: 1400 QQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTP 1459
Q KQ ++ PP Q+ Q PS ++ P P ++P + + P
Sbjct: 260 QGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPSQSSE---PSQPQQKDPQQPAQQQQP 316
Query: 1460 VQHGYLSPKPPSQQLGSPYRPHHSQ--SPQVGTPQREPQRNFYPAAQNL---------PA 1508
Q PK PS Q SP + + SP+ EP P + P
Sbjct: 317 AQQ----PKKPSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPP 372
Query: 1509 NTQQATSGTLFTQTPSGQSSAT-YSQFNQQSLNSTAP---PPP----PPPPPSSSYYQNQ 1560
+ + + L P G AT + AP PPP PPPPP SSY
Sbjct: 373 DRKPPLAAALGEAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPLPHRPPPPPPSSYMTGM 432
Query: 1561 QPSANF---QNYNQLKGSLSQQTVFTSGPNQ-ALPGTTSQQTVPGHHVTPGHFLPSQNPT 1616
++++ + Y L+ + T GP+ ALP P+ P
Sbjct: 433 STTSSYMSGEGYQSLQSMMK-----TEGPSYGALP-------------------PAYGPP 468
Query: 1617 IHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHH 1676
H V PP PPPPP P P P + + TPG T +
Sbjct: 469 AHLPYHPHVYPPNPPPPPVPPPPASFPPPA------------IPPPTPGYPPPPPTYNPN 516
Query: 1677 LPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVV---NSAPPPPPPPPP 1723
PPPPP P H PPHP GL A + PP PPP PP
Sbjct: 517 FPPPPPRLPPT--HAVPPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPP 564
Score = 78.6 bits (192), Expect = 5e-14
Identities = 97/343 (28%), Positives = 113/343 (32%), Gaps = 102/343 (29%)
Query: 1531 YSQFNQQSLNSTA----PPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGP 1586
YSQ QQ + T PP P P Q QPS Q+ S P
Sbjct: 258 YSQGKQQMPHHTPHQLQQPPSLQPTPQVPQVQQSQPS---------------QSSEPSQP 302
Query: 1587 NQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPP--------PPPPPAPG- 1637
Q P +QQ P PS P+ Q AVV P PPPP P
Sbjct: 303 QQKDPQQPAQQQQPAQQPKK----PSPQPSSPRQVKRAVVVSPKEENKAAEPPPPKIPKI 358
Query: 1638 -----PHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPP-----PGPA 1687
P P ++ +A +G A PG + +PPP P P P
Sbjct: 359 ETTHPPLPPAHPPPDRKPPLAAALG--EAEPPGPVDATDLPKVQIPPPAHPAPVHQPPPL 416
Query: 1688 PHHHPPPHPST---------------GLQGLQAQ-----------------------HQH 1709
PH PPP PS+ G Q LQ+ H H
Sbjct: 417 PHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHLPYHPH 476
Query: 1710 VVNSAPPPPP-PPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ--AT 1766
V PPPPP PPPP+S PP G P P + +P PP P + T
Sbjct: 477 VYPPNPPPPPVPPPPASF---------PPPAIPPPTPGYPPPPPTYNPNFPPPPPRLPPT 527
Query: 1767 HHTTLGPGPQHQPSGTG---PHCPLPVTGPHLQPQGPNSIPTP 1806
H P H P G G P P P QP P IP P
Sbjct: 528 HAV-----PPHPPPGLGLPPASYPPPAVPPGGQPPVPPPIPPP 565
Score = 53.5 bits (127), Expect = 2e-06
Identities = 96/412 (23%), Positives = 123/412 (29%), Gaps = 137/412 (33%)
Query: 1286 PCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQ 1345
P V S S PS PQ A+ P+ P P +P SP
Sbjct: 286 PQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPRQVKRAVVVSPKEEN 345
Query: 1346 NTCK-SPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAE-NGVHLKTELQQKQ 1403
+ PPK+ K + +P AH PD + + EAE G T+L + Q
Sbjct: 346 KAAEPPPPKIPKIETTHPPLP-PAH----PPPDRKPPLAAALGEAEPPGPVDATDLPKVQ 400
Query: 1404 LSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHG 1463
+ PP H P +H PP PH P
Sbjct: 401 I-----------PPPAH---------------PAPVHQPP----------PLPHRP---- 420
Query: 1464 YLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTP 1523
P PPS S + T Y + Q++ T G + P
Sbjct: 421 --PPPPPS-----------SYMTGMSTTSSYMSGEGYQSLQSM-----MKTEGPSYGALP 462
Query: 1524 SGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFT 1583
+ ++ PPPP PPPP+S
Sbjct: 463 PAYGPPAHLPYHPHVYPPNPPPPPVPPPPASF---------------------------- 494
Query: 1584 SGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPP-------PPPAP 1636
P A+P T PG+ P P+ NP PPPPP PP P
Sbjct: 495 --PPPAIPPPT-----PGYPPPP----PTYNPNF---------PPPPPRLPPTHAVPPHP 534
Query: 1637 GPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAP 1688
P L P S+ P AV PG +PPP PPPG P
Sbjct: 535 PPGLGLPPASY----------PPPAVPPGGQ-------PPVPPPIPPPGMPP 569
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 855
Score = 79.7 bits (195), Expect = 2e-14
Identities = 113/459 (24%), Positives = 157/459 (34%), Gaps = 95/459 (20%)
Query: 1416 PPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLG 1475
P H + + QL+ LP P PPS L+ P S P TP S P+ Q
Sbjct: 322 PATPHSSSLTCQLATPLPLAPPSPSAPPS--LQTLP--SPPATPPSQATTSLGSPTLQAT 377
Query: 1476 SPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFN 1535
+ P SP P + P P Q P+ L T +P ++
Sbjct: 378 HSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 1536 QQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTS 1595
AP PPP PP + + P A+ P T
Sbjct: 438 -------APFSPPPSPPVQAPFS---PPAS---------------------PPVSPSATP 466
Query: 1596 QQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHV 1655
P P +P P + +A PP PPP A P + +P ++A
Sbjct: 467 PSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA-- 524
Query: 1656 VGPVHAVT------PGSHIHSQTAGHHLPP---PPP-------------PPGP------- 1686
P+ A+ PG S +A + P PPP PP P
Sbjct: 525 TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQ 584
Query: 1687 APHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLA----SGHHTTSAQALHH- 1741
AP P P P T + G + + PPPPP PSS L+ +GH +++
Sbjct: 585 APRRPPTPGPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEEL 642
Query: 1742 PPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPN 1801
+ P ++A P PP A H GP PL G P P
Sbjct: 643 RGYDSGPEGGAAASP--PPDAELAACHPAAW--------SRGPAPPLAFRG---APGAP- 688
Query: 1802 SIPTPTASGFCPHPGS---VALPHGVQGPQQASPVPGQI 1837
+P P A+G PGS + + +GP+ A+P PG +
Sbjct: 689 -LPWPPATG----PGSADGLCTIYETEGPESATPAPGAL 722
Score = 77.8 bits (190), Expect = 9e-14
Identities = 145/568 (25%), Positives = 202/568 (35%), Gaps = 102/568 (17%)
Query: 1333 TTTNECPSPDTSQNTCKSPPKMSKPGSPGSVI-PAQAHGKIFTKPDPQWDSTVSASEAEN 1391
++ N P S ++PP +K SPG V P +A G P Q +SA E
Sbjct: 86 SSRNPASRPPASGRGERAPP--AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETVA 143
Query: 1392 GVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCP-PSPHLENP 1450
++ LS + + P T S ++++ + T++ P P+P
Sbjct: 144 RGKATEAPKRSALSAGARRDTSGPTPGT----PSPAMARRSRAAGTEVGLPRPAPSARPR 199
Query: 1451 PKSSTPHTPV----QHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNL 1506
P + P V +H P P +++ RP G QR R+ +A L
Sbjct: 200 PPTEGPRKSVSSASEHSTTEPSPAARR-----RPSAG-----GGLQRPASRSLSSSATPL 249
Query: 1507 PANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPP---------PPSSSYY 1557
+ A SG TP ++ A SQ + L + PP PP P SSS
Sbjct: 250 ---SSPARSGPSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL 304
Query: 1558 QNQQPSANFQNY-------NQLKGSLSQQTVFT---SGPNQALPGTTSQQTVPGHHVTPG 1607
PSA Q+ SL+ Q + P+ + P S QT+P TP
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAP--PSLQTLPSPPATP- 361
Query: 1608 HFLPSQ------NPTIHHQTAAAVVPPPP------PPPPAPG----PHLVQQPNSHQQHS 1651
PSQ +PT+ Q + +P PP PPP AP P L P+
Sbjct: 362 ---PSQATTSLGSPTL--QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPP 416
Query: 1652 VAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGP-APHHHPPPHPSTGLQGLQAQHQHV 1710
++ + P +H A PP PP P +P PP PS Q
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-----TPPSQAP 471
Query: 1711 VNSAPPP--PPPPPPSSVLASGHHTTSAQA----------LHHPPHQGPPLFPSSAHPTV 1758
+ A PP PP PP+S S T QA L PP Q PP + +
Sbjct: 472 PSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQAL 531
Query: 1759 PPYPSQATHHTTLGPG---PQHQPSGTGPHCPLPVTGPHLQ-PQGPNSIPTPTASGFCPH 1814
P P+ P P + P P + P LQ P P + PT A P
Sbjct: 532 PSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPT 591
Query: 1815 PG----------SVALPHGVQGPQQASP 1832
PG ++AL G P SP
Sbjct: 592 PGPDTSVSGPRLTLALAPGPPPPPSRSP 619
Score = 42.7 bits (99), Expect = 0.003
Identities = 124/607 (20%), Positives = 172/607 (28%), Gaps = 130/607 (21%)
Query: 1148 PQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGE 1207
P+ P + E ++ + S TE P P A G L SS+
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS---- 245
Query: 1208 QVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQ 1267
+ PL +PA S ++ P A S+ +Q V R+ +
Sbjct: 246 ------ATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 294
Query: 1268 RALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSS-------HSNHIP-QLQAKGPV---- 1315
LS SP + SPS S + HS+ + QL P+
Sbjct: 295 ALGPLSS----------SPLATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS 344
Query: 1316 ----PSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGK 1371
PS L P + TT+ P+ + + SPP P PA A
Sbjct: 345 PSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPP 404
Query: 1372 IFTKPDPQWDSTVS-----ASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSE 1426
+ P P +S + +A N L L Q S PP +
Sbjct: 405 LQAPPSPPASPPLSPLATPSPQAPNA--LAVHLLQAPFS----------PPPS------- 445
Query: 1427 QLSQKLPSVPTKLHCPPSPHLE---NPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHS 1483
P V P SP + PP + P + P PP+ P P +
Sbjct: 446 ------PPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA---SPPMSPSAT 496
Query: 1484 QSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTA 1543
PQ P P P L + S A +S ++ A
Sbjct: 497 PPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLA 556
Query: 1544 PPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHH 1603
PPP PP ++ PS P + P
Sbjct: 557 TPPPQAPPVLAAPLLQVPPS---------------------------PPASPTLQAPRRP 589
Query: 1604 VTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVT 1663
TPG P + + P PPPPP+ P HS + P
Sbjct: 590 PTPGPDTSVSGPRL-----TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRG 644
Query: 1664 PGSHIHSQTAGHHLPPPPPPPGPAPHHHPP-----PHPSTGLQGLQAQHQHVVNSAPPPP 1718
S A PPP HP P P +G AP P
Sbjct: 645 YDSGPEGGAAA-----SPPPDAELAACHPAAWSRGPAPPLAFRG-----------APGAP 688
Query: 1719 PPPPPSS 1725
P PP++
Sbjct: 689 LPWPPAT 695
>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
sequence-like 1 [Homo sapiens]
Length = 491
Score = 79.7 bits (195), Expect = 2e-14
Identities = 69/230 (30%), Positives = 87/230 (37%), Gaps = 55/230 (23%)
Query: 1629 PPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAP 1688
PPPP PAP H H ++ VV H + P H PPPPPP P
Sbjct: 308 PPPPAPAPAHH-------HPEYQGQPVVSHPHHIMPPQQ--------HYAPPPPPPPPI- 351
Query: 1689 HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPP--------PPPPSSVLASGHHTTSAQALH 1740
HP PHP A H+V S PPPP PPP ++A ++
Sbjct: 352 -SHPMPHPPQA-----AGTPHLVYSQAPPPPMTSAPPPITPPPGHIIAQ-----MPPYMN 400
Query: 1741 HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQH-QPSGTGPHCPLPVTGPHLQPQG 1799
HPP GPP P P P HH PQ + GT ++ P QP G
Sbjct: 401 HPP-PGPPPPQHGGPPVTAPPP----HHYNPNSLPQFTEDQGT-------LSPPFTQPGG 448
Query: 1800 PNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQVPPTFQ 1849
+ G P P P +QGP +P+PG + + P +Q
Sbjct: 449 -------MSPGIWPAPRGPPPPPRLQGPPSQTPLPGPHHPDQTRYRPYYQ 491
Score = 77.8 bits (190), Expect = 9e-14
Identities = 95/403 (23%), Positives = 132/403 (32%), Gaps = 101/403 (25%)
Query: 1396 KTELQQKQLSNN-NQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSS 1454
+T L Q+ L + N + P T R S E + + PT++ P + P K
Sbjct: 174 RTYLSQRDLQAHINHRHMRAGKPVT--RASLENVHPPIAPPPTEI---PERFIMPPDKHH 228
Query: 1455 TPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQAT 1514
H P + + P PP Q + P+ ++ + P PA ++ ++
Sbjct: 229 MSHIPPKQHIMMPPPPLQHV--PHEHYNQPHEDIRAP---------PAELSMAPPPPRSV 277
Query: 1515 SGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKG 1574
S F + S+ S + PPPP P P+ + + Q
Sbjct: 278 SQETFRISTRKHSNLITVPIQDDSNSGAREPPPPAPAPAHHHPEYQ-------------- 323
Query: 1575 SLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPP 1634
Q V H P H +P Q H+ PPPPPPPP
Sbjct: 324 ---------------------GQPVVSH---PHHIMPPQQ---HY------APPPPPPPP 350
Query: 1635 APGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP 1694
P P+ Q H+V +SQ PPPP P P PP
Sbjct: 351 ISHP----MPHPPQAAGTPHLV------------YSQA-----PPPPMTSAPPPITPPPG 389
Query: 1695 HPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSA 1754
H + AQ +N PP PPPP G +A HH P F
Sbjct: 390 H-------IIAQMPPYMNHPPPGPPPP------QHGGPPVTAPPPHHYNPNSLPQFTEDQ 436
Query: 1755 HPTVPPYPSQATHHTTLGP---GPQHQPSGTGPHCPLPVTGPH 1794
PP+ + P GP P GP P+ GPH
Sbjct: 437 GTLSPPFTQPGGMSPGIWPAPRGPPPPPRLQGPPSQTPLPGPH 479
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 79.3 bits (194), Expect = 3e-14
Identities = 104/411 (25%), Positives = 135/411 (32%), Gaps = 47/411 (11%)
Query: 1469 PPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSS 1528
PP LG+P P S +P V T +R L A+ QQ T TQ +
Sbjct: 13 PPPPPLGAPPPPPPS-APPVSTDTSSLRRADPKGRSALLADIQQGTRLRKVTQINDRSAP 71
Query: 1529 ATYSQ--FNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGP 1586
S N++ S PP + P + G + Q + P
Sbjct: 72 QIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTGQGPGSRAP 131
Query: 1587 NQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPP------PPPPPPAPGPHL 1640
+ LP +T+ G + P P T AA PP PPPP P P P
Sbjct: 132 SPRLPN----KTISGPLIPPAS--PRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPPP 185
Query: 1641 VQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP-HPSTG 1699
+ P +V P +T G+ +P PPPP P P PPP P++
Sbjct: 186 LPPPLPSSSPIKTPLVSPPGPLTKGN---LPVVAPPVPCAPPPPPPPPPPTPPPLPPASV 242
Query: 1700 LQGLQAQHQHVVNSAPPPPPP----PPPSSVLASGHHTTSAQALHHPPHQGPPLFP-SSA 1754
L + Q PP PPP PP + AQ PP PPL P +S
Sbjct: 243 LSDKAVKPQLAPLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASC 302
Query: 1755 HP----TVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASG 1810
P PP P + T P P PS P Q G ++P P A
Sbjct: 303 SPRASLPAPPLPGVNSSSETPPPLPPKSPSFQAPP----------QKAGAQALPAPPAP- 351
Query: 1811 FCPHPGSVAL----PHGVQGPQQASPVPGQIPIHRAQVPPTFQNNYHGSGW 1857
PGS HG G P P R+ + + W
Sbjct: 352 ----PGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTELSSKSQQATAW 398
Score = 57.0 bits (136), Expect = 2e-07
Identities = 90/358 (25%), Positives = 120/358 (33%), Gaps = 70/358 (19%)
Query: 1443 PSPHLEN--------PPKSST-PHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQR 1493
PSP L N PP S +T HG PP + +P P P P
Sbjct: 131 PSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPPPPP---PLP 187
Query: 1494 EPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPS 1553
P + P L + T G L P APPPPPPPPP
Sbjct: 188 PPLPSSSPIKTPLVSPPGPLTKGNLPVVAPPVPC---------------APPPPPPPPPP 232
Query: 1554 SSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQ 1613
+ P A+ + +K L+ + P L PG P P+Q
Sbjct: 233 TP---PPLPPASVLSDKAVKPQLAPLHLPPIPPPLPLLPPCGY---PGLKAEPAS--PAQ 284
Query: 1614 NPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQ-------HSVAHVVGPVHAVTPGS 1666
+ PP PPPP P P+ P + +S + P+ +P
Sbjct: 285 DAQ----------EPPAPPPPLP-PYASCSPRASLPAPPLPGVNSSSETPPPLPPKSPSF 333
Query: 1667 HIHSQTAGHH-LPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSS 1725
Q AG LP PP PPG P H G G + PPP PP+
Sbjct: 334 QAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLN-----------PPPAPPAR 382
Query: 1726 VLASGHHTTSAQALHHPPHQGP--PLFPSSAHPTVPPYPSQATHHTT--LGPGPQHQP 1779
+ + S QA P Q P L S H + + S+ T H+ P +++P
Sbjct: 383 SPTTELSSKSQQATAWTPTQQPGGQLRNGSLH-IIDDFESKFTFHSVEDFPPPDEYKP 439
Score = 45.1 bits (105), Expect = 7e-04
Identities = 93/407 (22%), Positives = 122/407 (29%), Gaps = 121/407 (29%)
Query: 1403 QLSNNNQA--LSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENPPKSS------ 1454
+L N ++A ++ PP+ +V P+ P PP P L P SS
Sbjct: 151 RLGNTSEAHGAARTAPPRPNV-----------PAPPPPTPPPPPPPLPPPLPSSSPIKTP 199
Query: 1455 --TPHTPVQHGYL------------SPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFY 1500
+P P+ G L P PP P P S + PQ P +
Sbjct: 200 LVSPPGPLTKGNLPVVAPPVPCAPPPPPPPPPPTPPPLPPASVLSDKAVKPQLAP-LHLP 258
Query: 1501 PAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQ 1560
P LP P G + P PPPP PP Y +
Sbjct: 259 PIPPPLP------------LLPPCGYPGLKAEPASPAQDAQEPPAPPPPLPP----YASC 302
Query: 1561 QPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIH-- 1618
P A+ P LPG S P LP ++P+
Sbjct: 303 SPRASL-------------------PAPPLPGVNSSSETPPP-------LPPKSPSFQAP 336
Query: 1619 HQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLP 1678
Q A A P PP PP P L ++ + PG+ G L
Sbjct: 337 PQKAGAQALPAPPAPPGSQPFLQKKRHGR----------------PGA------GGGKLN 374
Query: 1679 PPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGH----HTT 1734
PPP PP + P+T L Q A P P L +G
Sbjct: 375 PPPAPPARS--------PTTELSSKSQQ-------ATAWTPTQQPGGQLRNGSLHIIDDF 419
Query: 1735 SAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQHQPSG 1781
++ H PP P P YPS+ T GP Q + G
Sbjct: 420 ESKFTFHSVEDFPP--PDEYKPCQKIYPSKIPRSRTPGPWLQAEAVG 464
Score = 39.3 bits (90), Expect = 0.036
Identities = 20/49 (40%), Positives = 23/49 (46%), Gaps = 17/49 (34%)
Query: 1677 LPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSS 1725
+P PPPPP P P PPP P + + PPPPP PP S
Sbjct: 1 MPVPPPPPPPLP---PPPPP--------------LGAPPPPPPSAPPVS 32
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapiens]
Length = 816
Score = 78.6 bits (192), Expect = 5e-14
Identities = 112/451 (24%), Positives = 154/451 (34%), Gaps = 95/451 (21%)
Query: 1424 SSEQLSQKLPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHS 1483
SS L+ PS P PPS L+ P S P TP S P+ Q + P
Sbjct: 291 SSSPLATPSPSAPPSPSAPPS--LQTLP--SPPATPPSQATTSLGSPTLQATHSFLPSPP 346
Query: 1484 QSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTA 1543
SP P + P P Q P+ L T +P ++ A
Sbjct: 347 LSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-------A 399
Query: 1544 PPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHH 1603
P PPP PP + + P A+ P T P
Sbjct: 400 PFSPPPSPPVQAPFS---PPAS---------------------PPVSPSATPPSQAPPSL 435
Query: 1604 VTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVT 1663
P +P P + +A PP PPP A P + +P ++A P+ A+
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALA--TPPLQALP 493
Query: 1664 ------PGSHIHSQTAGHHLPP---PPP-------------PPGP-------APHHHPPP 1694
PG S +A + P PPP PP P AP P P
Sbjct: 494 SPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTP 553
Query: 1695 HPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLA----SGHHTTSAQALHH-PPHQGPPL 1749
P T + G + + PPPPP PSS L+ +GH +++ + P
Sbjct: 554 GPDTSVSGPRLTL--ALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPE 611
Query: 1750 FPSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTAS 1809
++A P PP A H GP PL G P P +P P A+
Sbjct: 612 GGAAASP--PPDAELAACHPAAW--------SRGPAPPLAFRG---APGAP--LPWPPAT 656
Query: 1810 GFCPHPGS---VALPHGVQGPQQASPVPGQI 1837
G PGS + + +GP+ A+P PG +
Sbjct: 657 G----PGSADGLCTIYETEGPESATPAPGAL 683
Score = 76.6 bits (187), Expect = 2e-13
Identities = 140/553 (25%), Positives = 198/553 (35%), Gaps = 103/553 (18%)
Query: 1332 PTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVI-PAQAHGKIFTKPDPQWDSTVSASEAE 1390
PT T+ P+ + ++PP +K SPG V P +A G P Q +SA E
Sbjct: 79 PTRTSRPPASGRGE---RAPP--AKNTSPGPVSSPGRASGTTRPGPLGQKGLRISAEETV 133
Query: 1391 NGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCP-PSPHLEN 1449
++ LS + + P T S ++++ + T++ P P+P
Sbjct: 134 ARGKATEAPKRSALSAGARRDTSGPTPGT----PSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 1450 PPKSSTPHTPV----QHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQN 1505
P + P V +H P P +++ RP G QR R+ +A
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARR-----RPSAG-----GGLQRPASRSLSSSATP 239
Query: 1506 LPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSAN 1565
L + A SG TP ++ A SQ + L + PP PP ++
Sbjct: 240 L---SSPARSGPSARGTP--RAPAHPSQPKPKGLQALRPPQVTPPRKDAA---------- 284
Query: 1566 FQNYNQLKGSLSQQTVFTSGPNQALPGTT---SQQTVPGHHVTPGHFLPSQ------NPT 1616
G LS + T P+ A P + S QT+P TP PSQ +PT
Sbjct: 285 -----PALGPLSSSPLATPSPS-APPSPSAPPSLQTLPSPPATP----PSQATTSLGSPT 334
Query: 1617 IHHQTAAAVVPPPP------PPPPAPG----PHLVQQPNSHQQHSVAHVVGPVHAVTPGS 1666
+ Q + +P PP PPP AP P L P+ ++ + P
Sbjct: 335 L--QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNAL 392
Query: 1667 HIHSQTAGHHLPPPPPPPGP-APHHHPPPHPSTGLQGLQAQHQHVVNSAPPP--PPPPPP 1723
+H A PP PP P +P PP PS Q + A PP PP PP
Sbjct: 393 AVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA-----TPPSQAPPSLAAPPLQVPPSPP 447
Query: 1724 SSVLASGHHTTSAQA----------LHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGP 1773
+S S T QA L PP Q PP + +P P+ P
Sbjct: 448 ASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSP 507
Query: 1774 G---PQHQPSGTGPHCPLPVTGPHLQ-PQGPNSIPTPTASGFCPHPG----------SVA 1819
P + P P + P LQ P P + PT A P PG ++A
Sbjct: 508 SASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLA 567
Query: 1820 LPHGVQGPQQASP 1832
L G P SP
Sbjct: 568 LAPGPPPPPSRSP 580
Score = 67.8 bits (164), Expect = 9e-11
Identities = 112/453 (24%), Positives = 153/453 (33%), Gaps = 77/453 (16%)
Query: 1436 PTKLHCPPSPHLEN--PPKSSTPHTPVQH-----GYLSPKPPSQQLGSPYRPHHSQSPQV 1488
PT+ PP+ PP +T PV G P P Q+ R ++
Sbjct: 79 PTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQK---GLRISAEETVAR 135
Query: 1489 GTPQREPQRNFYPAAQNLPANTQQATSG-TLFTQTPS--GQSSATYSQFNQQSLNSTAPP 1545
G P+R+ L A ++ TSG T T +P+ +S A ++ +A P
Sbjct: 136 GKATEAPKRSA------LSAGARRDTSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARP 189
Query: 1546 PPPPPPP-----SSSYYQNQQPSANFQNYNQLKG--------SLSQQTVFTSGPNQALPG 1592
PP P S+S + +PS + G SLS S P ++ P
Sbjct: 190 RPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPS 249
Query: 1593 TTSQQTVPGHH----------VTPGHFLPSQN---PTIHHQTAAAVVPPPPPPPPAPGPH 1639
P H + P P + P + +++ + P P PP+P
Sbjct: 250 ARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSA- 308
Query: 1640 LVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTG 1699
P S Q P A T Q LP PP P P PP +
Sbjct: 309 ----PPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPP--ALA 362
Query: 1700 LQGLQAQHQHVVNSAPPPPPPPPPSSVLAS-GHHTTSAQALH-----HPPHQGPPLFPSS 1753
L LQA PP PP PP S LA+ +A A+H P PP+
Sbjct: 363 LPPLQA---------PPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPF 413
Query: 1754 AHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASGFCP 1813
+ P PP AT P Q PS P P+ P P P P+ T P
Sbjct: 414 SPPASPPVSPSAT------PPSQAPPSLAAP----PLQVPPSPPASPPMSPSATPPPQAP 463
Query: 1814 HPGSVALPHGVQGPQQASPVPGQIPIHRAQVPP 1846
P + + P QA P P+ PP
Sbjct: 464 PPLAAPPLQLAKPPPQAPPALATPPLQALPSPP 496
Score = 43.5 bits (101), Expect = 0.002
Identities = 121/591 (20%), Positives = 166/591 (28%), Gaps = 128/591 (21%)
Query: 1148 PQNPPQKKKVSLLEYRKRQREARKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGE 1207
P+ P + E ++ + S TE P P A G L SS+
Sbjct: 181 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSS---- 236
Query: 1208 QVDHTASLPLPTPATVYNATSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQ 1267
+ PL +PA S ++ P A S+ +Q V R+ +
Sbjct: 237 ------ATPLSSPAR-----SGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAP 285
Query: 1268 RALLLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDP 1327
LS SP + SPS SPS+ PS L P
Sbjct: 286 ALGPLSS----------SPLATPSPS-APPSPSAP-------------PSLQTLPSPPAT 321
Query: 1328 ENPEPTTTNECPSPDTSQNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVS-- 1385
+ TT+ P+ + + SPP P PA A + P P +S
Sbjct: 322 PPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPL 381
Query: 1386 ---ASEAENGVHLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCP 1442
+ +A N L L Q S PP + P V P
Sbjct: 382 ATPSPQAPNA--LAVHLLQAPFS----------PPPS-------------PPVQAPFSPP 416
Query: 1443 PSPHLE---NPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNF 1499
SP + PP + P + P PP+ P P + PQ P P
Sbjct: 417 ASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA---SPPMSPSATPPPQAPPPLAAPPLQL 473
Query: 1500 YPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQN 1559
P L + S A +S ++ A PPP PP ++
Sbjct: 474 AKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQ 533
Query: 1560 QQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHH 1619
PS P + P TPG P +
Sbjct: 534 VPPS---------------------------PPASPTLQAPRRPPTPGPDTSVSGPRL-- 564
Query: 1620 QTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPP 1679
+ P PPPPP+ P HS + P S A
Sbjct: 565 ---TLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAA----- 616
Query: 1680 PPPPPGPAPHHHPP-----PHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSS 1725
PPP HP P P +G AP P P PP++
Sbjct: 617 SPPPDAELAACHPAAWSRGPAPPLAFRG-----------APGAPLPWPPAT 656
>gi|122937251 lysine (K)-specific demethylase 6B [Homo sapiens]
Length = 1682
Score = 77.8 bits (190), Expect = 9e-14
Identities = 118/467 (25%), Positives = 155/467 (33%), Gaps = 84/467 (17%)
Query: 1435 VPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQL---------GSPYRPHHSQS 1485
+P L PP P L PP P P G L+ PP Q G + P S
Sbjct: 240 LPPGLPLPPPP-LPPPPPPPPPPPPPLPG-LATSPPFQLTKPGLWSTLHGDAWGPERKGS 297
Query: 1486 PQVGTPQREPQRNF--YPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTA 1543
P+R+ QR+ +P PA T L P G + L +T
Sbjct: 298 ---APPERQEQRHSLPHPYPYPAPAYTAHPPGHRLVPAAPPGPGPRPPGAESHGCLPATR 354
Query: 1544 PP------------------PPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSG 1585
PP P Y ++ P + S S +
Sbjct: 355 PPGSDLRESRVQRSRMDSSVSPAATTACVPYAPSRPPGLPGTTTSSSSSSSSNTGLRGVE 414
Query: 1586 PNQALPGTTSQQTV-----------PGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPP 1634
PN +PG QT P H + FL + T H ++ P P PPP
Sbjct: 415 PNPGIPGADHYQTPALEVSHHGRLGPSAHSSRKPFLGAPAATPH----LSLPPGPSSPPP 470
Query: 1635 APGPHLVQQPNSHQQHSVAHVVGPV--HAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHP 1692
P P L++ P A + GP A G + G PP P PP P PH
Sbjct: 471 PPCPRLLRPPPPP-----AWLKGPACRAAREDGEILEELFFGTEGPPRPAPP-PLPHREG 524
Query: 1693 PPHPSTGLQGLQAQHQHVVNSAPPPPPPPPP----SSVLASGHHTTS-AQALHHPPHQGP 1747
P + Q H PP PP SS SG H++S A + PP P
Sbjct: 525 FLGPPASRFSVGTQDSHT-------PPTPPTPTTSSSNSNSGSHSSSPAGPVSFPP---P 574
Query: 1748 PLFPSSAHPTV-PPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPN---SI 1803
P S P PP P+Q L P P C +G +P+ P S
Sbjct: 575 PYLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCHQNTSGSFRRPESPRPRVSF 634
Query: 1804 PTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQV---PPT 1847
P G P PG ++ + PQ P G++P ++ PPT
Sbjct: 635 PKTPEVGPGPPPGPLS-----KAPQPVPPGVGELPARGPRLFDFPPT 676
Score = 58.9 bits (141), Expect = 4e-08
Identities = 113/482 (23%), Positives = 149/482 (30%), Gaps = 153/482 (31%)
Query: 1444 SPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRP-------------HHSQSPQVGT 1490
+PHL PP S+P P L P PP L P ++ P
Sbjct: 456 TPHLSLPPGPSSPPPPPCPRLLRPPPPPAWLKGPACRAAREDGEILEELFFGTEGPPRPA 515
Query: 1491 PQREPQRNFY--PAAQNLPANTQQA-TSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPP 1547
P P R + P A TQ + T T T T S +S + S + + + PPPP
Sbjct: 516 PPPLPHREGFLGPPASRFSVGTQDSHTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPP 575
Query: 1548 -------------------------------PPPPPSSSYYQNQQPSANFQNYNQLKGSL 1576
PP PPSS + Q S +F+ + +
Sbjct: 576 YLARSIDPLPRPPSPAQNPQDPPLVPLTLALPPAPPSSCH---QNTSGSFRRPESPRPRV 632
Query: 1577 SQQTVFTSGPNQALPGTTSQQTVPGHHVTPG-HFLPSQNPTI------------------ 1617
S GP PG S+ P V PG LP++ P +
Sbjct: 633 SFPKTPEVGPGPP-PGPLSKAPQP---VPPGVGELPARGPRLFDFPPTPLEDQFEEPAEF 688
Query: 1618 -----------------------HHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAH 1654
Q A V P PP P +Q P +
Sbjct: 689 KILPDGLANIMKMLDESIRKEEEQQQHEAGVAPQPPLKEPFAS---LQSP--FPTDTAPT 743
Query: 1655 VVGPVHAVTPGSHIHSQTAG---HHLPPPP--PPPGPAPHHHPPPHPSTGLQGLQAQHQH 1709
P AVT + + T PPP PPP P PP P
Sbjct: 744 TTAPAVAVTTTTTTTTTTTATQEEEKKPPPALPPPPPLAKFPPPSQPQ------------ 791
Query: 1710 VVNSAPPPPPPPPPSSVLASGHHTTSAQALHH----------------------PPHQGP 1747
PPPPPPP P+S+L S Q + PP
Sbjct: 792 -----PPPPPPPSPASLLKSLASVLEGQKYCYRGTGAAVSTRPGPLPTTQYSPGPPSGAT 846
Query: 1748 PLFPSSAHPTV-----PPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNS 1802
L P+SA P+ P S + T+ GP + + +G P P P+T QP P S
Sbjct: 847 ALPPTSAAPSAQGSPQPSASSSSQFSTSGGPWARERRAGEEP-VPGPMT--PTQPPPPLS 903
Query: 1803 IP 1804
+P
Sbjct: 904 LP 905
Score = 58.2 bits (139), Expect = 8e-08
Identities = 115/527 (21%), Positives = 155/527 (29%), Gaps = 99/527 (18%)
Query: 1284 ESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDT 1343
++P + S H + PS+HS+ P L A P L P P +P P P
Sbjct: 426 QTPALEVS-HHGRLGPSAHSSRKPFLGAPAATP---HLSLPPGPSSPPPPPCPRLLRPPP 481
Query: 1344 SQNTCKSPP--------------KMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEA 1389
K P G P P H + F P P +V ++
Sbjct: 482 PPAWLKGPACRAAREDGEILEELFFGTEGPPRPAPPPLPHREGFLGP-PASRFSVGTQDS 540
Query: 1390 ENGVHLKTELQQKQLSNNNQALSK-----NHPPQTHVRNSSEQL---------SQKLPSV 1435
T SN+ S + PP ++ S + L Q P V
Sbjct: 541 HTPPTPPTPTTSSSNSNSGSHSSSPAGPVSFPPPPYLARSIDPLPRPPSPAQNPQDPPLV 600
Query: 1436 PTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREP 1495
P L PP+P S+ H + P+ P ++ P P P G + P
Sbjct: 601 PLTLALPPAP-------PSSCHQNTSGSFRRPESPRPRVSFPKTPEVGPGPPPGPLSKAP 653
Query: 1496 QRNFYPAAQNLPAN------------TQQATSGTLFTQTPSG--------QSSATYSQFN 1535
Q P LPA Q F P G S +
Sbjct: 654 Q-PVPPGVGELPARGPRLFDFPPTPLEDQFEEPAEFKILPDGLANIMKMLDESIRKEEEQ 712
Query: 1536 QQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTS 1595
QQ AP PP P +S Q P +++ T T+ TT+
Sbjct: 713 QQHEAGVAPQPPLKEPFASL----QSPFPTDTAPTTTAPAVAVTTTTTT--------TTT 760
Query: 1596 QQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHV 1655
P LP P + PPPPPPP S A +
Sbjct: 761 TTATQEEEKKPPPALPPPPPLAKFPPPSQPQPPPPPPP-----------------SPASL 803
Query: 1656 VGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAP 1715
+ + +V G + G + PGP P P P +G L SA
Sbjct: 804 LKSLASVLEGQKYCYRGTGAAV---STRPGPLPTTQYSPGPPSGATALPP------TSAA 854
Query: 1716 PPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYP 1762
P P S +S +TS G P PT PP P
Sbjct: 855 PSAQGSPQPSASSSSQFSTSGGPWARERRAGEEPVPGPMTPTQPPPP 901
>gi|32698936 B-cell CLL/lymphoma 9-like [Homo sapiens]
Length = 1499
Score = 77.4 bits (189), Expect = 1e-13
Identities = 118/439 (26%), Positives = 162/439 (36%), Gaps = 98/439 (22%)
Query: 1424 SSEQLSQKLPSV-PTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPS-----QQLGSP 1477
S +Q S + +V T+L P P NPP T H+ G L +P Q+GSP
Sbjct: 871 SPDQSSMPMSNVGTTRLSHMPLPPASNPP--GTVHSAPNRG-LGRRPSDLTISINQMGSP 927
Query: 1478 YRPH--------------HSQSPQVGTPQREPQRNFYPAAQNL-PANTQQATSGTLFTQT 1522
H S S + +PQ Q P+A P + Q +L ++
Sbjct: 928 GMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLPSANPPGPLKSPQVLGSSLSVRS 987
Query: 1523 PSGQSSATYSQFNQQSLNSTAPPP-----PPPPPPSSSYYQNQQPSANFQNYNQLKGSLS 1577
P+G S +S + P P P PS QN+QP N + L ++
Sbjct: 988 PTGSPSRL------KSPSMAVPSPGWVASPKTAMPSPGVSQNKQPPLNMNSSTTLS-NME 1040
Query: 1578 QQTVFTSGP----------------NQALPGTTSQQTVPGHHVTP-------GHFLPSQN 1614
Q T+ SGP N +LP T+S P + + +PS
Sbjct: 1041 QGTLPPSGPRSSSSAPPANPPSGLMNPSLPFTSSPDPTPSQNPLSLMMTQMSKYAMPSST 1100
Query: 1615 PTIHH--QTAAA----VVP-----PPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVT 1663
P H+ +T A ++P PPPPPP GP + S+ Q S H+
Sbjct: 1101 PLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGI-----SNSQPSQMHLNSAAAQSP 1155
Query: 1664 PGSHIHSQTAGHHLPPPPPPPGPAP-HHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPP 1722
G ++ Q H PPP P P P + P HP+ QG Q+ + A P P
Sbjct: 1156 MGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNA--QGTGGPPQNSMMMA----PGGP 1209
Query: 1723 PSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPG-PQHQPSG 1781
S G +S+Q + PP P H + P T GPG QH PSG
Sbjct: 1210 DSLNAPCGPVPSSSQMMPFPPRLQQP------HGAMAP-----TGGGGGGPGLQQHYPSG 1258
Query: 1782 TGPHCPLPVTGPHLQPQGP 1800
LP QP GP
Sbjct: 1259 MA----LPPEDLPNQPPGP 1273
Score = 44.3 bits (103), Expect = 0.001
Identities = 35/115 (30%), Positives = 44/115 (38%), Gaps = 10/115 (8%)
Query: 1711 VNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTT 1770
++ AP PP P P + T +Q PP PP P SA P +PP
Sbjct: 276 LDQAPKVPPTPEPLPLSTPSAGTPQSQPPPLPPP--PPPAPGSAPPALPPEGPPEDSSQD 333
Query: 1771 LGPGPQHQPS------GTGPHCPLPVTGPHLQPQG--PNSIPTPTASGFCPHPGS 1817
L P S GT P+ P T + P G P+S P P G PG+
Sbjct: 334 LAPNSVGAASTGGGTGGTHPNTPTATTANNPLPPGGDPSSAPGPALLGEAAAPGN 388
Score = 43.9 bits (102), Expect = 0.001
Identities = 141/648 (21%), Positives = 199/648 (30%), Gaps = 137/648 (21%)
Query: 1281 SGGESP--CVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNEC 1338
SGG+ P +S + Q S + +P S L P NP P T +
Sbjct: 850 SGGQGPYQAMSQDMGNTQDMFSPDQSSMPMSNVGTTRLSHMPL---PPASNP-PGTVHSA 905
Query: 1339 PSPDTSQNTCKSPPKMSKPGSPG-----SVIPAQAHGKIFTKPDPQWDSTVSASEAENGV 1393
P+ + +++ GSPG S +Q H + T P S + S+
Sbjct: 906 PNRGLGRRPSDLTISINQMGSPGMGHLKSPTLSQVHSPLVTSPSANLKSPQTPSQMVPLP 965
Query: 1394 HLKTELQQKQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPS-VPTKLHCPPSPHL---EN 1449
K +LS P + R S ++ P V + PSP + +
Sbjct: 966 SANPPGPLKSPQVLGSSLSVRSPTGSPSRLKSPSMAVPSPGWVASPKTAMPSPGVSQNKQ 1025
Query: 1450 PP---KSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQS-------PQVGTPQREPQRNF 1499
PP SST + ++ G L P P +P P + S P +P P +N
Sbjct: 1026 PPLNMNSSTTLSNMEQGTLPPSGPRSSSSAP--PANPPSGLMNPSLPFTSSPDPTPSQN- 1082
Query: 1500 YPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAP--PPPPPPPPSSSYY 1557
L Q + + + TP ++ + L P PPPPPP S
Sbjct: 1083 -----PLSLMMTQMSKYAMPSSTPLYHNAIKTIATSDDELLPDRPLLPPPPPPQGSGPGI 1137
Query: 1558 QNQQPSANFQNYNQLKGSLS-----QQTVFTSGPNQALPGTTSQ-QTVPGHHVTPGHFLP 1611
N QPS N + + QQ + P LP T +P H G P
Sbjct: 1138 SNSQPSQMHLNSAAAQSPMGMNLPGQQPLSHEPPPAMLPSPTPLGSNIPLHPNAQGTGGP 1197
Query: 1612 SQNPTI-------------------------------------------------HHQTA 1622
QN + H +
Sbjct: 1198 PQNSMMMAPGGPDSLNAPCGPVPSSSQMMPFPPRLQQPHGAMAPTGGGGGGPGLQQHYPS 1257
Query: 1623 AAVVPPPPPPPPAPGPHLVQQPNSH-QQHSVAHVVGPVH--AVTPG--SHIHSQTAGHHL 1677
+PP P PGP P H ++A +G + V PG S ++ +
Sbjct: 1258 GMALPPEDLPNQPPGP---MPPQQHLMGKAMAGRMGDAYPPGVLPGVASVLNDPELSEVI 1314
Query: 1678 PPPPP--PPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTS 1735
P P P P PS+ L Q+ S PP PP+ L + + +
Sbjct: 1315 RPTPTGIPEFDLSRIIPSEKPSSTL-------QYFPKSENQPPKAQPPNLHLMNLQNMMA 1367
Query: 1736 AQALHHPPH----QGPP--LFPSSAHP---------TVPPYPSQATHHTTLGPGPQHQPS 1780
Q PP+ QG L S HP VPP H L G P
Sbjct: 1368 EQTPSRPPNLPGQQGVQRGLNMSMCHPGQMSLLGRTGVPPQQGMVPH--GLHQGVMSPPQ 1425
Query: 1781 G------------TGPHCPLPVTGPH-LQPQGPNSIPTPTASGFCPHP 1815
G G + PH L PQG P P + HP
Sbjct: 1426 GLMTQQNFMLMKQRGVGGEVYSQPPHMLSPQGSLMGPPPQQNLMVSHP 1473
Score = 41.2 bits (95), Expect = 0.010
Identities = 74/281 (26%), Positives = 93/281 (33%), Gaps = 63/281 (22%)
Query: 1548 PPPPPSSSYYQNQQPSANFQNYNQLKG------SLSQQTVFTSGPNQALPGTTSQQTVPG 1601
P PPS Y AN L+G + QQ V + +QA + + +P
Sbjct: 232 PGKPPSQFVYVFTTHLANTAAEAVLQGRADSILAYHQQNVPRAKLDQAPKVPPTPEPLPL 291
Query: 1602 HHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPG---PHLVQQ-----------PNSH 1647
TP P P P PPPPPPAPG P L + PNS
Sbjct: 292 S--TPSAGTPQSQPP----------PLPPPPPPAPGSAPPALPPEGPPEDSSQDLAPNSV 339
Query: 1648 QQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPP---PPPPPGPA----------------- 1687
S G H TP + TA + LPP P PGPA
Sbjct: 340 GAASTGGGTGGTHPNTP----TATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVG 395
Query: 1688 ---PHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPH 1744
H LQ L+ + ++ S P P +G AQA PP
Sbjct: 396 SEGLSKEQLEHRERSLQTLRDIERLLLRSGETEPFLKGPPG--GAGEGGPPAQA-PPPPQ 452
Query: 1745 QGPPLFPSSAHPTVPPYPSQATHHTTLGPGP-QHQPSGTGP 1784
Q P PS P S + +LG P +H+ G P
Sbjct: 453 QPPTAPPSGLKKYEEPLQSMISQTQSLGGPPLEHEVPGHPP 493
Score = 38.5 bits (88), Expect = 0.062
Identities = 73/307 (23%), Positives = 100/307 (32%), Gaps = 57/307 (18%)
Query: 1442 PPSPHLENPPKSSTPHTPVQHGY---LSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRN 1498
P +PH PP P P G + KPPSQ + + H + + Q
Sbjct: 207 PGAPH--GPPPGLRPDAPGGGGGGGGVPGKPPSQFV-YVFTTHLANTAAEAVLQGRADSI 263
Query: 1499 FYPAAQNLP-ANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYY 1557
QN+P A QA TP +T S QS P PPPPPP S
Sbjct: 264 LAYHQQNVPRAKLDQAPK---VPPTPEPLPLSTPSAGTPQS--QPPPLPPPPPPAPGSAP 318
Query: 1558 QNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTI 1617
P ++ +Q PN +T T H TP
Sbjct: 319 PALPPEGPPEDSSQ-----------DLAPNSVGAASTGGGTGGTHPNTP----------- 356
Query: 1618 HHQTAAAVVPPPPPPPPAPGPHLVQQ---PNSHQQHSVA----------HVVGPVHAVTP 1664
TA +PP P APGP L+ + P + Q+ V H + +
Sbjct: 357 TATTANNPLPPGGDPSSAPGPALLGEAAAPGNGQRSLVGSEGLSKEQLEHRERSLQTLRD 416
Query: 1665 GSHI---HSQTAGHHLPPP-------PPPPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSA 1714
+ +T PP PP P P PP P +GL+ + Q +++
Sbjct: 417 IERLLLRSGETEPFLKGPPGGAGEGGPPAQAPPPPQQPPTAPPSGLKKYEEPLQSMISQT 476
Query: 1715 PPPPPPP 1721
PP
Sbjct: 477 QSLGGPP 483
>gi|21361376 splicing factor 3a, subunit 2 [Homo sapiens]
Length = 464
Score = 77.0 bits (188), Expect = 2e-13
Identities = 76/211 (36%), Positives = 87/211 (41%), Gaps = 55/211 (26%)
Query: 1627 PPPPP--PPPAPGPHLVQQPNSHQQHSVAHVVGP-VHAVTPGSH-----IHSQTAGHHLP 1678
PP PP PPPAPG H P H S H P VH PG H +H T+G H P
Sbjct: 274 PPGPPQLPPPAPGVH-PPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP 332
Query: 1679 PP---PPPPG---PAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPP---PPPPSSV--L 1727
P PP PG PAP HPP PP P PPP + V
Sbjct: 333 APGVHPPAPGVHPPAPGVHPP-----------------APGVHPPAPGVHPPPSAGVHPQ 375
Query: 1728 ASGHHTTSAQALH------HPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGPQH---Q 1778
A G H +A A+H HPP P + P + P V P P H + G PQ
Sbjct: 376 APGVH-PAAPAVHPQAPGVHPP--APGMHPQA--PGVHPQP-PGVHPSAPGVHPQPPGVH 429
Query: 1779 PSGTGPHCPL---PVTGPHLQPQGPNSIPTP 1806
PS G H P P+ P L +GP +IP P
Sbjct: 430 PSNPGVHPPTPMPPMLRPPLPSEGPGNIPPP 460
Score = 68.9 bits (167), Expect = 4e-11
Identities = 81/335 (24%), Positives = 106/335 (31%), Gaps = 46/335 (13%)
Query: 1376 PDPQWDSTVSASEAENGVHLKTELQQKQLSNNN-----QALSKNHPPQTHVRNSSEQLSQ 1430
PD +W + A+E + K ++ + +K Q H +
Sbjct: 162 PDRRWQYLLMAAEPYETIAFKVPSREIDKAEGKFWTHWNRETKQFFLQFHFKMEKPPAPP 221
Query: 1431 KLPSVPTKLHCPPSPHLEN-PPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVG 1489
LP+ P + PP P + PP+ P + L P PP G P P P
Sbjct: 222 SLPAGPPGVKRPPPPLMNGLPPRPPLPES------LPPPPPG---GLPLPPMPPTGPAPS 272
Query: 1490 TPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPP 1549
P PQ + PA + + P A PP P
Sbjct: 273 GPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAP----------GVHPPAPGV 322
Query: 1550 PPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHF 1609
PP+S + P+ V P P PG H P
Sbjct: 323 HPPTSGVHP---PAPGVHP--------PAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAG 371
Query: 1610 LPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGP-VHAVTPGSHI 1668
+ Q P +H A P PPAPG H Q P H Q H P VH PG +
Sbjct: 372 VHPQAPGVHPAAPAVHPQAPGVHPPAPGMH-PQAPGVHPQPPGVHPSAPGVHPQPPG--V 428
Query: 1669 HSQTAGHHLPPPPPP------PGPAPHHHPPPHPS 1697
H G H P P PP P P + PPP P+
Sbjct: 429 HPSNPGVHPPTPMPPMLRPPLPSEGPGNIPPPPPT 463
Score = 66.6 bits (161), Expect = 2e-10
Identities = 70/235 (29%), Positives = 82/235 (34%), Gaps = 22/235 (9%)
Query: 1539 LNSTAPPPP-----PPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQT--VFTSGPNQALP 1591
+N P PP PPPPP P+ + L V P P
Sbjct: 238 MNGLPPRPPLPESLPPPPPGGLPLPPMPPTGPAPSGPPGPPQLPPPAPGVHPPAPVVHPP 297
Query: 1592 GTTSQQTVPG-HHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQH 1650
+ PG H PG P+ P +H T+ P P PPAPG H P H
Sbjct: 298 ASGVHPPAPGVHPPAPGVHPPA--PGVHPPTSGVHPPAPGVHPPAPGVH-PPAPGVHPPA 354
Query: 1651 SVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPP---HPSTGLQGLQAQH 1707
H P P + +H Q G H P P AP HPP HP G+ Q
Sbjct: 355 PGVHPPAPGVHPPPSAGVHPQAPGVH-PAAPAVHPQAPGVHPPAPGMHPQA--PGVHPQP 411
Query: 1708 QHVVNSAPPPPPPPPPSSVLASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYP 1762
V SAP P PP G H + PP PPL PS +PP P
Sbjct: 412 PGVHPSAPGVHPQPPGVHPSNPGVHPPTPM----PPMLRPPL-PSEGPGNIPPPP 461
Score = 58.2 bits (139), Expect = 8e-08
Identities = 58/190 (30%), Positives = 64/190 (33%), Gaps = 33/190 (17%)
Query: 1678 PPPPP--PPGPAPHHHPPPHPSTGLQGLQAQHQHVVNSAPPPP------PPPPPSSVLAS 1729
PP PP P GP PPP GL + S PPPP PP PP+ S
Sbjct: 217 PPAPPSLPAGPPGVKRPPPPLMNGL----PPRPPLPESLPPPPPGGLPLPPMPPTGPAPS 272
Query: 1730 G-----HHTTSAQALH------HPPHQGPPLFPSSAHPTVPPY--PSQATHHTTLG---P 1773
G A +H HPP G HP P P+ H T G P
Sbjct: 273 GPPGPPQLPPPAPGVHPPAPVVHPPASGVHPPAPGVHPPAPGVHPPAPGVHPPTSGVHPP 332
Query: 1774 GPQHQPSGTGPHCPLP---VTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGV--QGPQ 1828
P P G H P P P + P P P P+A PG V Q P
Sbjct: 333 APGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGVHPAAPAVHPQAPG 392
Query: 1829 QASPVPGQIP 1838
P PG P
Sbjct: 393 VHPPAPGMHP 402
Score = 37.0 bits (84), Expect = 0.18
Identities = 64/274 (23%), Positives = 83/274 (30%), Gaps = 35/274 (12%)
Query: 1286 PCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPEN-PEPTTTNECPSPDTS 1344
P + P V+ P N +P P P E + P P P P P+P
Sbjct: 221 PSLPAGPPGVKRPPPPLMNGLP------PRPPLPESLPPPPPGGLPLPPMPPTGPAPSGP 274
Query: 1345 QNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQL 1404
+ PP P V+ A G P P GVH
Sbjct: 275 PGPPQLPPPAPGVHPPAPVVHPPASG--VHPPAP-------------GVHPPAPGVHPPA 319
Query: 1405 SNNNQALSKNHPPQTHVRNSSEQLSQKLPSV--PTKLHCPPSPHLENPPKSST-PHTPVQ 1461
+ S HPP V + + P V P PP+P + PP + P P
Sbjct: 320 PGVHPPTSGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPAPGVHPPPSAGVHPQAPGV 379
Query: 1462 HGYLSPKPPSQQLGSPYRPH-HSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFT 1520
H P P P H Q+P V PQ P P + G +
Sbjct: 380 HPAAPAVHPQAPGVHPPAPGMHPQAPGVH-PQPPGVHPSAPGVHPQPPGVHPSNPG-VHP 437
Query: 1521 QTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSS 1554
TP + L S P PPPPP++
Sbjct: 438 PTPM-------PPMLRPPLPSEGPGNIPPPPPTN 464
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 76.3 bits (186), Expect = 3e-13
Identities = 143/663 (21%), Positives = 214/663 (32%), Gaps = 127/663 (19%)
Query: 1221 ATVYNATSEETSNNCP--------VKDATASEKNEPEVQWTAST--SVEQVRERSYQRAL 1270
A V+N TS +S P +K T P + T S E E S
Sbjct: 64 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSE-- 121
Query: 1271 LLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENP 1330
++ S S S + ++SS +S +N +LQ K V + P P
Sbjct: 122 -----NQESSSSSSSSSSSSTIRKIKSSKNSAANR--ELQKKLKVKDNKKNRTKKKP-TP 173
Query: 1331 EPTTTNECPS-----------PDTS---QNTCKSPPKMS--KPGSPGSVIPAQAHGKIFT 1374
+P +E S PDTS N + PK++ KP +P +P +
Sbjct: 174 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD----- 228
Query: 1375 KPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQT---HVRNSSEQLSQK 1431
++ E V+ +T ++ K+ + N+ S + +T S E+ S K
Sbjct: 229 ----------TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 278
Query: 1432 LPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTP 1491
+ +K+ P+P E K TP + +PK P+ +P P + T
Sbjct: 279 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST--TPKEPTPTTIKSAPTT 336
Query: 1492 QREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPP 1551
+EP +A P T+ TP + + T ++ + +AP P P
Sbjct: 337 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPA 395
Query: 1552 PSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLP 1611
P++ P + P TT ++ P TP
Sbjct: 396 PTT-------------------------------PKKPAP-TTPKEPAP---TTP----K 416
Query: 1612 SQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQ 1671
PT + A P P P P P ++P A A T
Sbjct: 417 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------- 468
Query: 1672 TAGHHLPPPPPPPGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSV 1726
T P P P P AP P P+T SAP P P P++
Sbjct: 469 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT------------TKSAPTTPKEPSPTTT 516
Query: 1727 LASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGP--QHQPSGTGP 1784
TT + P + P P PT P P+ TT P P +P+ T P
Sbjct: 517 KEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTP 572
Query: 1785 HCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQV 1844
P T L P P + T P P + P +P +A
Sbjct: 573 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 632
Query: 1845 PPT 1847
P T
Sbjct: 633 PNT 635
Score = 73.9 bits (180), Expect = 1e-12
Identities = 112/527 (21%), Positives = 174/527 (33%), Gaps = 68/527 (12%)
Query: 1291 SPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKS 1350
+P+ +S+P++ P K P P+ + P+ P PTT E P+P T + +
Sbjct: 380 APTTTKSAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTT 437
Query: 1351 P--PKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNN 1408
P P + P P P + +P P S + T + + +
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---------TPKEPAPTTTKS 488
Query: 1409 QALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENP--PKSSTPHTPVQHGYLS 1466
+ P T +++ + P+ TK P +P P PK P TP + +
Sbjct: 489 APTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 547
Query: 1467 PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQ 1526
PK P+ P ++ P TP +EP A P T T L TP
Sbjct: 548 PKEPA--------PTTTKKPAPTTP-KEP-------APTTPKETAPTTPKKLTPTTPEKL 591
Query: 1527 SSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGP 1586
+ T + + AP P P P++ ++P+ + + + P
Sbjct: 592 APTTPEKPAPTTPEELAPTTPEEPTPTTP----EEPAPT-----------TPKAAAPNTP 636
Query: 1587 NQALPGTTSQQTVPGHHVTPGHFLPSQN-PTIHHQTAAAVVPPPPPPPPAPGPHLVQQPN 1645
+ P TT ++ P P P + PT TA + P P P P
Sbjct: 637 KEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695
Query: 1646 SHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQA 1705
+ ++ + P G+ P P PAP P P+T
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGT------------APTTPKEPAPTTPKEPAPTTPKGTAPT 743
Query: 1706 QHQHVVNSAPPPPPPPPPSSVLASGH-HTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
+ + P P P + G TTS + P + P P PT P P+
Sbjct: 744 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 803
Query: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVT---GPHLQPQGPNSIPTPTA 1808
T T P P T P T P ++ PTP A
Sbjct: 804 TTPET---PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 847
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 76.3 bits (186), Expect = 3e-13
Identities = 143/663 (21%), Positives = 214/663 (32%), Gaps = 127/663 (19%)
Query: 1221 ATVYNATSEETSNNCP--------VKDATASEKNEPEVQWTAST--SVEQVRERSYQRAL 1270
A V+N TS +S P +K T P + T S E E S
Sbjct: 105 AEVHNPTSPPSSKKAPPPSGASQTIKSTTKRSPKPPNKKKTKKVIESEEITEEHSVSE-- 162
Query: 1271 LLSDHRKDKDSGGESPCVSCSPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENP 1330
++ S S S + ++SS +S +N +LQ K V + P P
Sbjct: 163 -----NQESSSSSSSSSSSSTIRKIKSSKNSAANR--ELQKKLKVKDNKKNRTKKKP-TP 214
Query: 1331 EPTTTNECPS-----------PDTS---QNTCKSPPKMS--KPGSPGSVIPAQAHGKIFT 1374
+P +E S PDTS N + PK++ KP +P +P +
Sbjct: 215 KPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSD----- 269
Query: 1375 KPDPQWDSTVSASEAENGVHLKTELQQKQLSNNNQALSKNHPPQT---HVRNSSEQLSQK 1431
++ E V+ +T ++ K+ + N+ S + +T S E+ S K
Sbjct: 270 ----------TSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAK 319
Query: 1432 LPSVPTKLHCPPSPHLENPPKSSTPHTPVQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTP 1491
+ +K+ P+P E K TP + +PK P+ +P P + T
Sbjct: 320 DLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPAST--TPKEPTPTTIKSAPTT 377
Query: 1492 QREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQSSATYSQFNQQSLNSTAPPPPPPPP 1551
+EP +A P T+ TP + + T ++ + +AP P P
Sbjct: 378 PKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPK-EPAPTTTKEPAPTTTKSAPTTPKEPA 436
Query: 1552 PSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGPNQALPGTTSQQTVPGHHVTPGHFLP 1611
P++ P + P TT ++ P TP
Sbjct: 437 PTT-------------------------------PKKPAP-TTPKEPAP---TTP----K 457
Query: 1612 SQNPTIHHQTAAAVVPPPPPPPPAPGPHLVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQ 1671
PT + A P P P P P ++P A A T
Sbjct: 458 EPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPT-------- 509
Query: 1672 TAGHHLPPPPPPPGP-----APHHHPPPHPSTGLQGLQAQHQHVVNSAPPPPPPPPPSSV 1726
T P P P P AP P P+T SAP P P P++
Sbjct: 510 TTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTT------------TKSAPTTPKEPSPTTT 557
Query: 1727 LASGHHTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQATHHTTLGPGP--QHQPSGTGP 1784
TT + P + P P PT P P+ TT P P +P+ T P
Sbjct: 558 KEPAP-TTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPT---TTKKPAPTTPKEPAPTTP 613
Query: 1785 HCPLPVTGPHLQPQGPNSIPTPTASGFCPHPGSVALPHGVQGPQQASPVPGQIPIHRAQV 1844
P T L P P + T P P + P +P +A
Sbjct: 614 KETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAA 673
Query: 1845 PPT 1847
P T
Sbjct: 674 PNT 676
Score = 73.9 bits (180), Expect = 1e-12
Identities = 112/527 (21%), Positives = 174/527 (33%), Gaps = 68/527 (12%)
Query: 1291 SPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTTTNECPSPDTSQNTCKS 1350
+P+ +S+P++ P K P P+ + P+ P PTT E P+P T + +
Sbjct: 421 APTTTKSAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPTPTTPKE-PAPTTKEPAPTT 478
Query: 1351 P--PKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQLSNNN 1408
P P + P P P + +P P S + T + + +
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPT---------TPKEPAPTTTKS 529
Query: 1409 QALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENP--PKSSTPHTPVQHGYLS 1466
+ P T +++ + P+ TK P +P P PK P TP + +
Sbjct: 530 APTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTT 588
Query: 1467 PKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQTPSGQ 1526
PK P+ P ++ P TP +EP A P T T L TP
Sbjct: 589 PKEPA--------PTTTKKPAPTTP-KEP-------APTTPKETAPTTPKKLTPTTPEKL 632
Query: 1527 SSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVFTSGP 1586
+ T + + AP P P P++ ++P+ + + + P
Sbjct: 633 APTTPEKPAPTTPEELAPTTPEEPTPTTP----EEPAPT-----------TPKAAAPNTP 677
Query: 1587 NQALPGTTSQQTVPGHHVTPGHFLPSQN-PTIHHQTAAAVVPPPPPPPPAPGPHLVQQPN 1645
+ P TT ++ P P P + PT TA + P P P P
Sbjct: 678 KEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736
Query: 1646 SHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQGLQA 1705
+ ++ + P G+ P P PAP P P+T
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGT------------APTTPKEPAPTTPKEPAPTTPKGTAPT 784
Query: 1706 QHQHVVNSAPPPPPPPPPSSVLASGH-HTTSAQALHHPPHQGPPLFPSSAHPTVPPYPSQ 1764
+ + P P P + G TTS + P + P P PT P P+
Sbjct: 785 TLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAP 844
Query: 1765 ATHHTTLGPGPQHQPSGTGPHCPLPVT---GPHLQPQGPNSIPTPTA 1808
T T P P T P T P ++ PTP A
Sbjct: 845 TTPET---PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 888
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 75.5 bits (184), Expect = 5e-13
Identities = 136/699 (19%), Positives = 225/699 (32%), Gaps = 64/699 (9%)
Query: 1167 REARKSGSKTENFPLISVSPHASGSLSNNGDGCASSNDNGEQVDHTASLPLPTPATVYNA 1226
++ +K+ +K + P V A L N + + + Q + ++ P T A N
Sbjct: 67 KDNKKNRTKKKPTPKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINP 126
Query: 1227 TSEETSNNCPVKDATASEKNEPEVQWTASTSVEQVRERSYQRALLLSDHRKDKDSGGESP 1286
N+ K+ + + E V+ +T+ + + + + +
Sbjct: 127 RPSLPPNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKD 186
Query: 1287 CVSCSPSHVQSSPSSHSNHI-PQLQA-KGPVPSFSELMEDPDPENPEPTTTNECPS--PD 1342
S + +P + + P L K P P+ + P+ P PTT P+ +
Sbjct: 187 LAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKE 246
Query: 1343 TSQNTCKSPPKMSKPGSPGSV-IPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQ 1401
+ T KS P K +P + PA T +P +T + T +
Sbjct: 247 PAPTTTKSAPTTPKEPAPTTTKEPAPT-----TPKEPAPTTTKEPAPTTTKSAPTTPKEP 301
Query: 1402 KQLSNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENP--PKSSTPHTP 1459
+ A + P + K P+ TK P +P P PK P TP
Sbjct: 302 APTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTP 361
Query: 1460 VQHGYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLF 1519
+ +PK P+ P + P T + P PA P T+ A +
Sbjct: 362 KEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA----PTTTKSAPT---- 413
Query: 1520 TQTPSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQ 1579
TP S T + + AP P P P++ P + + +
Sbjct: 414 --TPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTT-------PKEPAPTTPKEPAPTTTK 464
Query: 1580 TVFTSGPNQALPGTTSQQTVPGHHVTPGHFLPSQNPTIHHQTAAAVVPPPPPPPPAPGPH 1639
+ P + P TT ++T P TP P T + P P PAP
Sbjct: 465 KPAPTTPKEPAP-TTPKETAP---TTPKKLTP---------TTPEKLAPTTPEKPAPTTP 511
Query: 1640 LVQQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTG 1699
P + ++ + P + ++ P P P PAP P P+T
Sbjct: 512 EELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKE----PAPTTPKEPAPTTPKEPAPTTP 567
Query: 1700 LQGLQAQHQHVV-----NSAPPPPPPPPPSSVLASGHHTTSAQALHHP----PHQGPPLF 1750
+ + AP P P P + + ++ P P P
Sbjct: 568 KETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 1751 PSSAHPTVPPYPSQATHHTTLGPGPQHQPSGTGPHCPLPVTGPHLQPQGPNSIPTPTASG 1810
P PT P P+ T T P +P+ T P P P +GP S + +
Sbjct: 628 PKEPAPTTPKEPAPTTPKGT-APTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAP 686
Query: 1811 FCPHPGSVALPH--GVQGPQQASPVPGQIPIHRAQVPPT 1847
P + P P++ +P + P PPT
Sbjct: 687 TTPKETAPTTPKEPAPTTPKKPAPTTPETP------PPT 719
Score = 73.9 bits (180), Expect = 1e-12
Identities = 113/531 (21%), Positives = 175/531 (32%), Gaps = 76/531 (14%)
Query: 1291 SPSHVQSSPSSHSNHIPQLQAKGPVPSFSELMEDPDPENPEPTT------TNECPSPDTS 1344
+P+ +S+P++ P K P P+ + P+ P PTT T + P+P T
Sbjct: 287 APTTTKSAPTTPKEPAPTTPKK-PAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Query: 1345 QNTCKSPPKMSKPGSPGSVIPAQAHGKIFTKPDPQWDSTVSASEAENGVHLKTELQQKQL 1404
+ + PK P +P P T +P +T S T +
Sbjct: 346 KEPAPTAPKKPAPTTPKEPAPT-------TPKEPAPTTTKEPSPT-------TPKEPAPT 391
Query: 1405 SNNNQALSKNHPPQTHVRNSSEQLSQKLPSVPTKLHCPPSPHLENP--PKSSTPHTPVQH 1462
+ + + P T +++ + P+ TK P +P P PK P TP +
Sbjct: 392 TTKSAPTTTKEPAPTTTKSAPTTPKEPSPTT-TKEPAPTTPKEPAPTTPKKPAPTTPKEP 450
Query: 1463 GYLSPKPPSQQLGSPYRPHHSQSPQVGTPQREPQRNFYPAAQNLPANTQQATSGTLFTQT 1522
+PK P+ P ++ P TP +EP A P T T L T
Sbjct: 451 APTTPKEPA--------PTTTKKPAPTTP-KEP-------APTTPKETAPTTPKKLTPTT 494
Query: 1523 PSGQSSATYSQFNQQSLNSTAPPPPPPPPPSSSYYQNQQPSANFQNYNQLKGSLSQQTVF 1582
P + T + + AP P P P++ ++P+ + +
Sbjct: 495 PEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTP----EEPAPT-----------TPKAAA 539
Query: 1583 TSGPNQALPGTTSQQTVPGHHVTPGHFLPSQN-PTIHHQTAAAVVPPPPPPPPAPGPHLV 1641
+ P + P TT ++ P P P + PT TA + P P P
Sbjct: 540 PNTPKEPAP-TTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKE 598
Query: 1642 QQPNSHQQHSVAHVVGPVHAVTPGSHIHSQTAGHHLPPPPPPPGPAPHHHPPPHPSTGLQ 1701
P + ++ + P G+ P P PAP P P+T
Sbjct: 599 LAPTTTKEPTSTTCDKPAPTTPKGT------------APTTPKEPAPTTPKEPAPTTPKG 646
Query: 1702 GLQAQHQHVVNSAPPPPPPPPPSSVLASG-HHTTSAQALHHPPHQGPPLFPSSAHPTVPP 1760
+ + P P P + G TTS + P + P P PT P
Sbjct: 647 TAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK 706
Query: 1761 YPSQATHHTTLGPGPQHQPSGTGPHCPLPVT---GPHLQPQGPNSIPTPTA 1808
P+ T T P P T P T P ++ PTP A
Sbjct: 707 KPAPTTPET---PPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKA 754
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.127 0.382
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 96,100,984
Number of Sequences: 37866
Number of extensions: 6258322
Number of successful extensions: 90548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 573
Number of HSP's successfully gapped in prelim test: 2209
Number of HSP's that attempted gapping in prelim test: 35283
Number of HSP's gapped (non-prelim): 29384
length of query: 1858
length of database: 18,247,518
effective HSP length: 117
effective length of query: 1741
effective length of database: 13,817,196
effective search space: 24055738236
effective search space used: 24055738236
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.