Search of human proteins with 89357932

Search of human proteins with 89357932

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|89357932 keratin 5b [Homo sapiens]
         (520 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|89357932 keratin 5b [Homo sapiens]                                1018   0.0  
gi|109255249 keratin 4 [Homo sapiens]                                 501   e-142
gi|119395754 keratin 5 [Homo sapiens]                                 493   e-139
gi|5031839 keratin 6A [Homo sapiens]                                  492   e-139
gi|155969697 keratin 6C [Homo sapiens]                                489   e-138
gi|119703753 keratin 6B [Homo sapiens]                                488   e-138
gi|28173564 keratin 73 [Homo sapiens]                                 482   e-136
gi|153791158 keratin 75 [Homo sapiens]                                473   e-133
gi|153791670 keratin 76 [Homo sapiens]                                469   e-132
gi|32567786 keratin 6L [Homo sapiens]                                 464   e-131
gi|119395750 keratin 1 [Homo sapiens]                                 463   e-130
gi|109148552 keratin 3 [Homo sapiens]                                 460   e-129
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       459   e-129
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      459   e-129
gi|15618995 keratin 71 [Homo sapiens]                                 457   e-128
gi|148612803 keratin 6 irs4 [Homo sapiens]                            456   e-128
gi|194018511 keratin 77 [Homo sapiens]                                437   e-122
gi|47132620 keratin 2 [Homo sapiens]                                  433   e-121
gi|67782365 keratin 7 [Homo sapiens]                                  420   e-117
gi|4504919 keratin 8 [Homo sapiens]                                   413   e-115
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      397   e-110
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    371   e-103
gi|4504935 keratin 85 [Homo sapiens]                                  367   e-101
gi|27477127 keratin 82 [Homo sapiens]                                 354   9e-98
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   349   3e-96
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   346   3e-95
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   346   3e-95
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   346   3e-95
gi|14318422 keratin 86 [Homo sapiens]                                 346   3e-95
gi|169790841 keratin 83 [Homo sapiens]                                345   6e-95

>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score = 1018 bits (2632), Expect = 0.0
 Identities = 520/520 (100%), Positives = 520/520 (100%)

Query: 1   MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGG 60
           MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGG
Sbjct: 1   MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGG 60

Query: 61  RLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNN 120
           RLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNN
Sbjct: 61  RLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNN 120

Query: 121 QFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGER 180
           QFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGER
Sbjct: 121 QFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGER 180

Query: 181 GALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALR 240
           GALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALR
Sbjct: 181 GALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALR 240

Query: 241 EYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEA 300
           EYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEA
Sbjct: 241 EYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEA 300

Query: 301 EALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDA 360
           EALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDA
Sbjct: 301 EALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDA 360

Query: 361 EQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGE 420
           EQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGE
Sbjct: 361 EQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGE 420

Query: 421 ECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIIL 480
           ECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIIL
Sbjct: 421 ECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIIL 480

Query: 481 GSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKTSITY 520
           GSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKTSITY
Sbjct: 481 GSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKTSITY 520


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  501 bits (1290), Expect = e-142
 Identities = 280/512 (54%), Positives = 352/512 (68%), Gaps = 34/512 (6%)

Query: 10  RGFSARSACSARSRGRSRGGFSS-----------RGGFSSRSLNSF-------------- 44
           RGFS  SA      G  RG FSS            GGF SRSL +               
Sbjct: 87  RGFSCGSAIVG---GGKRGAFSSVSMSGGAGRCSSGGFGSRSLYNLRGNKSISMSVAGSR 143

Query: 45  -GGCLEGSRG-STWGSGGRLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDP 102
            G C  G+ G  T G GG  G  F    GGPG  +CP GGIQEVTINQ+LLTPL +EIDP
Sbjct: 144 QGACFGGAGGFGTGGFGGGFGGSFSG-KGGPGFPVCPAGGIQEVTINQSLLTPLHVEIDP 202

Query: 103 QFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVF 162
           + Q VRT+E ++I+ LNN+FASFIDKV+FLEQQNKVLETKW+LLQQQ  + S + LEP+F
Sbjct: 203 EIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNLLQQQTTTTSSKNLEPLF 262

Query: 163 EACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDV 222
           E  L  LRKQL+ L  ++G L +ELK  +D  E++K+KYEEE ++R   ENDFVVLKKDV
Sbjct: 263 ETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEINKRTAAENDFVVLKKDV 322

Query: 223 DGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSII 282
           D  +L+K+ELE K+++L + + FLK L + EL Q+QT  SDTSVVLSMDNNR LD  SII
Sbjct: 323 DAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTSVVLSMDNNRNLDLDSII 382

Query: 283 TEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQ 342
            EVRA+YEEIA+ SKAEAEALYQTK Q+LQ+S   HGD ++ TK +I++L++ IQRL+++
Sbjct: 383 AEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNTKSEIAELNRMIQRLRAE 442

Query: 343 TENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTST 402
            EN+KKQ  +LQ ++ DAEQRGE ALKDA +K  ELEAAL+ AK+ LAR+L EYQEL S 
Sbjct: 443 IENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSV 502

Query: 403 KLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKG 462
           KL+LD+EIATYR+LLEGEE RMSGEC S V+IS V GS   +GG+ GGLGS  G G   G
Sbjct: 503 KLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGS-TSTGGISGGLGSGSGFGLSSG 561

Query: 463 SPGSCCTSIVTGGSNIILGSGKDPVLDSCSVS 494
                 +    GGS  + GS    ++ + +++
Sbjct: 562 FGSGSGSGFGFGGS--VSGSSSSKIISTTTLN 591


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  493 bits (1268), Expect = e-139
 Identities = 278/543 (51%), Positives = 363/543 (66%), Gaps = 31/543 (5%)

Query: 1   MSLSPCRAQRGFSARSACSARSRGR-----SRGGFSSRGGFSSRSLNSFGGCLEGSRGST 55
           +SL+      G+ +RS  +     R     S G F +R G  +     FGG      G  
Sbjct: 49  VSLAGACGVGGYGSRSLYNLGGSKRISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFG 108

Query: 56  WGSGGRLGVR----FGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQE 111
            G+GG  G+     FG   GGPG  +CPPGGIQEVT+NQ+LLTPL ++IDP  Q VRT+E
Sbjct: 109 GGAGGGFGLGGGAGFGGGFGGPGFPVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEE 168

Query: 112 TQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRK 171
            ++I+TLNN+FASFIDKVRFLEQQNKVL+TKW LLQ+QG    +Q LEP+FE  ++ LR+
Sbjct: 169 REQIKTLNNKFASFIDKVRFLEQQNKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRR 228

Query: 172 QLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKME 231
           QL+ + GERG LD+EL+  +D  E++K+KYE+E ++R T EN+FV+LKKDVD  +++K+E
Sbjct: 229 QLDSIVGERGRLDSELRNMQDLVEDFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVE 288

Query: 232 LEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEE 291
           LE K++AL + + F+K   + EL Q+QT  SDTSVVLSMDNNR LD  SII EV+A+YEE
Sbjct: 289 LEAKVDALMDEINFMKMFFDAELSQMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEE 348

Query: 292 IARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNA 351
           IA  S+ EAE+ YQTKY+ELQ +A  HGD ++ TK +IS++++ IQRL+++ +N+KKQ A
Sbjct: 349 IANRSRTEAESWYQTKYEELQQTAGRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCA 408

Query: 352 SLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIA 411
           +LQ AI DAEQRGELALKDA+ K+ ELE AL+ AKQ++ARLL EYQEL +TKL+LDVEIA
Sbjct: 409 NLQNAIADAEQRGELALKDARNKLAELEEALQKAKQDMARLLREYQELMNTKLALDVEIA 468

Query: 412 TYRRLLEGEECRMSGECTSQVTISSV--------GGSAVMSGGVGGGLGSTCGLGSGKGS 463
           TYR+LLEGEECR+SGE    V IS V        G  +   GG+GGGLG   G G   GS
Sbjct: 469 TYRKLLEGEECRLSGEGVGPVNISVVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGS 528

Query: 464 PGSCCTS----------IVTGGSNIILGSGKDPVLDSCSVSGSSAGSSCHTILKKTVESS 513
            GS  +S          +  GGS     SG+   +      GS  GSS       T  SS
Sbjct: 529 SGSYYSSSSGGVGLGGGLSVGGSGFSASSGRGLGVG----FGSGGGSSSSVKFVSTTSSS 584

Query: 514 LKT 516
            K+
Sbjct: 585 RKS 587


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  492 bits (1266), Expect = e-139
 Identities = 286/561 (50%), Positives = 369/561 (65%), Gaps = 64/561 (11%)

Query: 8   AQRGFSARSACSARSRGRSRGGFSS------RG-----------GFSSRSLNSFGGCLE- 49
           ++RGFSA SA   R  G SR GFSS      RG           GF SRSL   GG    
Sbjct: 14  SRRGFSANSA---RLPGVSRSGFSSVSVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRI 70

Query: 50  -----------------------GSRGSTWGSGGRLGVRFGEWSG--------GPGLSLC 78
                                  G  GS +G GG  G+ FG   G        GPG  +C
Sbjct: 71  SIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVC 130

Query: 79  PPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKV 138
           PPGGIQEVT+NQ+LLTPL ++IDP  Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKV
Sbjct: 131 PPGGIQEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 190

Query: 139 LETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYK 198
           LETKW LLQ+QG    +Q LEP+FE  ++ LR+QL+ + GERG LD+EL+  +D  E++K
Sbjct: 191 LETKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFK 250

Query: 199 SKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQ 258
           +KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K + L + + FL+ L + EL Q+Q
Sbjct: 251 NKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQ 310

Query: 259 TQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLH 318
           T  SDTSVVLSMDNNR LD  SII EV+A+YEEIA+ S+AEAE+ YQTKY+ELQV+A  H
Sbjct: 311 THISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRH 370

Query: 319 GDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDEL 378
           GD ++ TK +I+++++ IQRL+S+ +++KKQ A+LQAAI DAEQRGE+ALKDA+ K++ L
Sbjct: 371 GDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGL 430

Query: 379 EAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVG 438
           E AL+ AKQ+LARLL EYQEL + KL+LDVEIATYR+LLEGEECR++GE   QV IS V 
Sbjct: 431 EDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVV- 489

Query: 439 GSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSG--S 496
             + +S G GG  G   GLG G GS  S  + +  GG      SG+       ++ G  S
Sbjct: 490 -QSTVSSGYGGASGVGSGLGLGGGSSYSYGSGLGVGG-GFSSSSGR-------AIGGGLS 540

Query: 497 SAGSSCHTILKKTVESSLKTS 517
           S G    TI   T  SS + S
Sbjct: 541 SVGGGSSTIKYTTTSSSSRKS 561


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  489 bits (1258), Expect = e-138
 Identities = 285/561 (50%), Positives = 368/561 (65%), Gaps = 64/561 (11%)

Query: 8   AQRGFSARSACSARSRGRSRGGFSS------RG-----------GFSSRSLNSFGGCLE- 49
           ++RGFSA SA   R  G SR GFSS      RG           GF SRSL   GG    
Sbjct: 14  SRRGFSANSA---RLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRI 70

Query: 50  -----------------------GSRGSTWGSGGRLGVRFGEWSG--------GPGLSLC 78
                                  G  GS +G GG  G+ FG   G        GPG  +C
Sbjct: 71  SIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVC 130

Query: 79  PPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKV 138
           PPGGIQEVT+NQ+LLTPL ++IDP  Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKV
Sbjct: 131 PPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 190

Query: 139 LETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYK 198
           L+TKW LLQ+QG    +Q LEP+FE  ++ LR+QL+ + GERG LD+EL+  +D  E+ K
Sbjct: 191 LDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLK 250

Query: 199 SKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQ 258
           +KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K + L + + FL+ L + EL Q+Q
Sbjct: 251 NKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQ 310

Query: 259 TQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLH 318
           T  SDTSVVLSMDNNR LD  SII EV+A+YEEIA+ S+AEAE+ YQTKY+ELQV+A  H
Sbjct: 311 THISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRH 370

Query: 319 GDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDEL 378
           GD ++ TK +I+++++ IQRL+S+ +++KKQ ASLQAAI DAEQRGE+ALKDA+ K++ L
Sbjct: 371 GDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGL 430

Query: 379 EAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVG 438
           E AL+ AKQ+LARLL EYQEL + KL+LDVEIATYR+LLEGEECR++GE   QV +S V 
Sbjct: 431 EDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVV- 489

Query: 439 GSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSG--S 496
             + +S G GG  G   GLG G GS  S  + +  GG      SG+       ++ G  S
Sbjct: 490 -QSTISSGYGGASGVGSGLGLGGGSSYSYGSGLGIGG-GFSSSSGR-------AIGGGLS 540

Query: 497 SAGSSCHTILKKTVESSLKTS 517
           S G    TI   T  SS + S
Sbjct: 541 SVGGGSSTIKYTTTSSSSRKS 561


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  488 bits (1257), Expect = e-138
 Identities = 284/560 (50%), Positives = 366/560 (65%), Gaps = 62/560 (11%)

Query: 8   AQRGFSARSACSARSRGRSRGGFSS------RG-----------GFSSRSLNSFGGCLE- 49
           ++RGFSA SA   R  G SR GFSS      RG           GF SRSL   GG    
Sbjct: 14  SRRGFSANSA---RLPGVSRSGFSSISVSRSRGSGGLGGACGGAGFGSRSLYGLGGSKRI 70

Query: 50  -----------------------GSRGSTWGSGGRLGVRFGEWSG--------GPGLSLC 78
                                  G  GS +G GG  G+ FG   G        GPG  +C
Sbjct: 71  SIGGGSCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVC 130

Query: 79  PPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKV 138
           PPGGIQEVT+NQ+LLTPL ++IDP  Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKV
Sbjct: 131 PPGGIQEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKV 190

Query: 139 LETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYK 198
           L+TKW LLQ+QG    +Q LEP+FE  ++ LR+QL+ + GERG LD+EL+  +D  E+ K
Sbjct: 191 LDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLK 250

Query: 199 SKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQ 258
           +KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K + L + + FL+ L + EL Q+Q
Sbjct: 251 NKYEDEINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQ 310

Query: 259 TQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLH 318
           T  SDTSVVLSMDNNR LD  SII EV+A+YEEIA+ S+AEAE+ YQTKY+ELQ++A  H
Sbjct: 311 THISDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRH 370

Query: 319 GDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDEL 378
           GD ++ TK +I+++++ IQRL+S+ +++KKQ A+LQAAI DAEQRGE+ALKDA+ K++ L
Sbjct: 371 GDDLRNTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGL 430

Query: 379 EAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSVG 438
           E AL+ AKQ+LARLL EYQEL + KL+LDVEIATYR+LLEGEECR++GE   QV IS V 
Sbjct: 431 EDALQKAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVV- 489

Query: 439 GSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSG-SS 497
             + +S G GG  G   GLG G GS  S        GS + +G G        +  G SS
Sbjct: 490 -QSTVSSGYGGASGVGSGLGLGGGSSYSY-------GSGLGVGGGFSSSSGRATGGGLSS 541

Query: 498 AGSSCHTILKKTVESSLKTS 517
            G    TI   T  SS + S
Sbjct: 542 VGGGSSTIKYTTTSSSSRKS 561


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  482 bits (1240), Expect = e-136
 Identities = 277/511 (54%), Positives = 346/511 (67%), Gaps = 25/511 (4%)

Query: 4   SPCRAQRGFSARSACSARSRGRS--RGGFSSRGGFSSRSLNSFGGCLEGS----RGSTWG 57
           S   A+ GFS  SA  +     S   GG    GGFSSRSL S GG    S     GS W 
Sbjct: 9   SGAAAKGGFSGCSAVLSGGSSSSYRAGGKGLSGGFSSRSLYSLGGARSISFNVASGSGWA 68

Query: 58  SG---------GRLGVRFGEWS-GGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVV 107
            G         G  G  FG  + G    SLCPPGGI +VTIN++LL PL +E+DP+ Q V
Sbjct: 69  GGYGFGRGRASGFAGSMFGSVALGSVCPSLCPPGGIHQVTINKSLLAPLNVELDPEIQKV 128

Query: 108 RTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLD 167
           R QE ++I+ LNN+FASFIDKVRFLEQQN+VLETKW LLQQ  L+  +  LEP+ E  + 
Sbjct: 129 RAQEREQIKVLNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYIS 188

Query: 168 QLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFL 227
            LRKQLE L G+R  LD+EL++ R+  E+YK +YEEE ++R T EN+FVVLKKDVD  + 
Sbjct: 189 NLRKQLETLSGDRVRLDSELRSVREVVEDYKKRYEEEINKRTTAENEFVVLKKDVDAAYT 248

Query: 228 SKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRA 287
           SK+EL+ K++AL   + F K L E E  Q+Q+  SDTS++LSMDNNR LD  SII EVRA
Sbjct: 249 SKVELQAKVDALDGEIKFFKCLYEGETAQIQSHISDTSIILSMDNNRNLDLDSIIAEVRA 308

Query: 288 RYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLK 347
           +YEEIAR SKAEAEALYQTK+QELQ++A  HGD ++ TK +IS+L + IQRL+S+ E++K
Sbjct: 309 QYEEIARKSKAEAEALYQTKFQELQLAAGRHGDDLKHTKNEISELTRLIQRLRSEIESVK 368

Query: 348 KQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLD 407
           KQ A+L+ AI DAEQRG+ ALKDA+AK+DELE AL+ AK+ LAR+L EYQEL S KLSLD
Sbjct: 369 KQCANLETAIADAEQRGDCALKDARAKLDELEGALQQAKEELARMLREYQELLSVKLSLD 428

Query: 408 VEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLG-STCGLGSGKGSPGS 466
           +EIATYR+LLEGEECRMSGE T+ V+IS +  S     G G G G S  G      S  S
Sbjct: 429 IEIATYRKLLEGEECRMSGEYTNSVSISVINSSMAGMAGTGAGFGFSNAGTYGYWPSSVS 488

Query: 467 CCTSIVTGGSNIILGSGKDPVLDSCSVSGSS 497
              S++ GG   + GSG      +CS  G +
Sbjct: 489 GGYSMLPGG--CVTGSG------NCSPRGEA 511


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  473 bits (1217), Expect = e-133
 Identities = 273/536 (50%), Positives = 360/536 (67%), Gaps = 30/536 (5%)

Query: 2   SLSPCRAQRGFSARSACSARSRGRSRGGFSSRGG-FSSRSLNSFGGCLEGSR---GSTW- 56
           +++P   +  FS+ S   + +     G  SS G  F SRSL + GG    S    GS+  
Sbjct: 22  AITPAAGRSRFSSVSVARSAAGSGGLGRISSAGASFGSRSLYNLGGAKRVSINGCGSSCR 81

Query: 57  -GSGGRLGVRFGEWSG------------GPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQ 103
            G GGR   RFG  SG            GP   +CPPGGIQEVT+NQ+LLTPL ++IDP 
Sbjct: 82  SGFGGRASNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPT 141

Query: 104 FQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFE 163
            Q VR +E ++I+TLNN+FASFIDKVRFLEQQNKVLETKW LLQ+QG    +Q LEP+F+
Sbjct: 142 IQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFD 201

Query: 164 ACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVD 223
           +   +LR+QLE +  ERG L+AEL+  +D  E++K +YE+E ++R   EN+FV LKKDVD
Sbjct: 202 SYTSELRRQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVD 261

Query: 224 GVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIIT 283
             +++K+ELE K+++L E + F+  + + EL QLQTQ  DTSVVLSMDNNR LD  SII 
Sbjct: 262 AAYMNKVELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIA 321

Query: 284 EVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQT 343
           EV+A+YE+IA  S+AEAE+ YQTKY+ELQV+A  HGD ++ TK +IS++++ IQRL+++ 
Sbjct: 322 EVKAQYEDIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEI 381

Query: 344 ENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTK 403
           +++KKQ +SLQ AI DAEQRGELALKDA+AK+ +LE AL+ AKQ++ARLL EYQEL + K
Sbjct: 382 DSVKKQCSSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIK 441

Query: 404 LSLDVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGL---GSTCGLGSG 460
           L+LDVEIATYR+LLEGEECR+SGE  S V IS V  ++ +S G G G    G   GLG G
Sbjct: 442 LALDVEIATYRKLLEGEECRLSGEGVSPVNISVV--TSTLSSGYGSGSSIGGGNLGLGGG 499

Query: 461 KGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSSAGSSCHTILKKTVESSLKT 516
            G       S  T G +  LG+G      S + +    GS        T  SS K+
Sbjct: 500 SG------YSFTTSGGH-SLGAGLGGSGFSATSNRGLGGSGSSVKFVSTTSSSQKS 548


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  469 bits (1207), Expect = e-132
 Identities = 269/498 (54%), Positives = 335/498 (67%), Gaps = 27/498 (5%)

Query: 24  GRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCP---- 79
           GRS  GF+  GG+      S+GG   G RG   G GG  G       GGPG+   P    
Sbjct: 84  GRSSCGFA--GGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGAGGFGGPGVFGGPGSFG 141

Query: 80  ----------PGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKV 129
                     PGGIQEV +NQ+LL PL +EIDPQ   V+ QE ++I+TLNN+FASFIDKV
Sbjct: 142 GPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKV 201

Query: 130 RFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKA 189
           RFLEQQNKVLETKW LLQQQ        LEP FE+ +  L KQL+ L GERG L+ ELK+
Sbjct: 202 RFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQLDSLLGERGNLEGELKS 261

Query: 190 CRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHL 249
            +D  E++K KYE+E ++R   EN+FV LKKDVD  F++K+EL+ K+++L + + FL+ L
Sbjct: 262 MQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQAKVDSLTDEVSFLRTL 321

Query: 250 NEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQ 309
            E EL Q+Q+ ASDTSVVLSMDNNR LD  SII EVRA+YEEIA+ SK+EAEALYQTK  
Sbjct: 322 YEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIAQRSKSEAEALYQTKLG 381

Query: 310 ELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALK 369
           ELQ +A  HGD ++ TK +I +L++ IQRL+++ EN+KKQNA+LQ AI +AEQRGE+ALK
Sbjct: 382 ELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANLQTAIAEAEQRGEMALK 441

Query: 370 DAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECT 429
           DA AK+ +L+ AL+ AK +LARLL +YQEL + KL+LDVEIATYR+LLEGEECRMSGEC 
Sbjct: 442 DANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGECQ 501

Query: 430 SQVTISSVGGSAVMSGGVG---GGLGSTCGLGSGKGSPGSCCTSI----VTGGSNIILGS 482
           S V IS V      SG  G   G  G   G GSG    GS  +S     V+GGS    GS
Sbjct: 502 SAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGS----GS 557

Query: 483 GKDPVLDSCSVSGSSAGS 500
           G   V    +    S+GS
Sbjct: 558 GYGGVSSGSTGGRGSSGS 575


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  464 bits (1194), Expect = e-131
 Identities = 268/504 (53%), Positives = 346/504 (68%), Gaps = 33/504 (6%)

Query: 24  GRSRGGFSSR-----GGFSSRSLNSFGGCLEGSRGSTWGSGGR--LGVRFGEWSGGPGLS 76
           G   GGF SR     GG  S S++  GG L G     +G G R  +G   G  + GP   
Sbjct: 51  GPGTGGFGSRSLYNLGGHKSISVSVAGGALLGRALGGFGFGSRAFMGQGAGRQTFGPA-- 108

Query: 77  LCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQN 136
            CPPGGIQEVT+NQ+LLTPL +EIDP+ Q VRTQE ++I+TLNN+FASFIDKVRFLEQQN
Sbjct: 109 -CPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKTLNNKFASFIDKVRFLEQQN 167

Query: 137 KVLETKWHLLQQQG--LSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQE 194
           KVLETKW LLQ+QG  L  ++  LEP+FEA L  +R  L++LQ ERG LD+EL+  +D  
Sbjct: 168 KVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDRLQSERGRLDSELRNVQDLV 227

Query: 195 EEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEEL 254
           E++K+KYE+E ++    EN+FVVLKKDVD  ++ +M+L GK+  L + + FL+ L E EL
Sbjct: 228 EDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGKVGTLTQEIDFLQQLYEMEL 287

Query: 255 GQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVS 314
            Q+QT  S+T+VVLSMDNNR LD  SII EV+A+YE IA+ S+AEAEA YQTKY+ELQV+
Sbjct: 288 SQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQRSRAEAEAWYQTKYEELQVT 347

Query: 315 AQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAK 374
           A  HGD +++TK +I++L + IQRLQ + +  KKQ   LQ AI +AEQRGELALKDAQ K
Sbjct: 348 AGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQTAIAEAEQRGELALKDAQKK 407

Query: 375 VDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTI 434
           + +L+ AL  AK++L RLL +YQEL + KL+LDVEIATYR+LLE EE RMSGEC S V+I
Sbjct: 408 LGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRKLLESEESRMSGECPSAVSI 467

Query: 435 SSVGGSAVMSGGVGGGLGSTCGL-GSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSV 493
           S  G S  + GG     G    L GSG  + G   T++   G + + G    PV      
Sbjct: 468 SVTGNSTTVCGGGAASFGGGISLGGSGGATKGGFSTNV---GYSTVKGG---PV------ 515

Query: 494 SGSSAGSSCHTILKKTVESSLKTS 517
              SAG+S   IL+KT  +++KTS
Sbjct: 516 ---SAGTS---ILRKT--TTVKTS 531


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  463 bits (1192), Expect = e-130
 Identities = 251/478 (52%), Positives = 344/478 (71%), Gaps = 11/478 (2%)

Query: 24  GRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCPPGGI 83
           G   GGF   GGF    +   G    GS G  +G GG  G   G + GG G  +CPPGGI
Sbjct: 98  GFGGGGFGG-GGFGGGGIGGGGFGGFGSGGGGFGGGGFGG---GGYGGGYG-PVCPPGGI 152

Query: 84  QEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKW 143
           QEVTINQ+LL PL +EIDP+ Q V+++E ++I++LNNQFASFIDKVRFLEQQN+VL+TKW
Sbjct: 153 QEVTINQSLLQPLNVEIDPEIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKW 212

Query: 144 HLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEE 203
            LLQQ   S     LEP FE+ ++ LR++++QL+ ++  LD+ELK  +D  E+Y++KYE+
Sbjct: 213 ELLQQVDTSTRTHNLEPYFESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYED 272

Query: 204 EAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASD 263
           E ++R   EN+FV +KKDVDG +++K++L+ KL+ L++ + FL  L + EL Q+QTQ S+
Sbjct: 273 EINKRTNAENEFVTIKKDVDGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISE 332

Query: 264 TSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQ 323
           T+V+LSMDNNR LD  SII EV+A+YE+IA+ SKAEAE+LYQ+KY+ELQ++A  HGD ++
Sbjct: 333 TNVILSMDNNRSLDLDSIIAEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVR 392

Query: 324 ETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALR 383
            +K++IS+L++ IQRL+S+ +N+KKQ ++LQ +I+DAEQRGE ALKDA+ K+++LE AL+
Sbjct: 393 NSKIEISELNRVIQRLRSEIDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQ 452

Query: 384 MAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTIS-SVGGSAV 442
            AK++LARLL +YQEL +TKL+LD+EIATYR LLEGEE RMSGEC   V++S S   + +
Sbjct: 453 QAKEDLARLLRDYQELMNTKLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTI 512

Query: 443 MSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVLDSCSVSGSSAGS 500
             GG  GG G   G GSG  S GS   S  +GG     G G+       S  GS  GS
Sbjct: 513 SGGGSRGGGGG--GYGSGGSSYGSGGGSYGSGGGG---GGGRGSYGSGGSSYGSGGGS 565



 Score = 31.6 bits (70), Expect = 1.8
 Identities = 27/77 (35%), Positives = 34/77 (44%), Gaps = 9/77 (11%)

Query: 6   CRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVR 65
           C      S  ++ +  S G SRGG    GG+ S      GG   GS G ++GSGG  G  
Sbjct: 497 CAPNVSVSVSTSHTTISGGGSRGG--GGGGYGS------GGSSYGSGGGSYGSGGGGGGG 548

Query: 66  FGEWSGGPGLSLCPPGG 82
            G +  G G S    GG
Sbjct: 549 RGSYGSG-GSSYGSGGG 564



 Score = 30.8 bits (68), Expect = 3.1
 Identities = 21/49 (42%), Positives = 23/49 (46%), Gaps = 1/49 (2%)

Query: 26 SRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPG 74
          SR G+ S GGFSS S          +  ST  SGG  G RF    GG G
Sbjct: 7  SRSGYRSGGGFSSGSAGIINYQRRTTSSSTRRSGGG-GGRFSSCGGGGG 54



 Score = 30.4 bits (67), Expect = 4.1
 Identities = 24/55 (43%), Positives = 26/55 (47%), Gaps = 7/55 (12%)

Query: 19  SARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGS---RGSTWG----SGGRLGVRF 66
           S  S G  RGG    GG SS    S GG   GS   RGS+ G    SGG   V+F
Sbjct: 580 SGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKF 634


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  460 bits (1183), Expect = e-129
 Identities = 260/470 (55%), Positives = 323/470 (68%), Gaps = 28/470 (5%)

Query: 28  GGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCP-------- 79
           GGF   GGF       FGG   G  G   G GG  G       GGPG    P        
Sbjct: 117 GGFGGAGGFGGAG--GFGGA--GGFGGPGGFGGSGGF------GGPGSLGSPGGFGPGGF 166

Query: 80  PGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVL 139
           PGGIQEVTINQ+LL PL +EIDPQ   V+ QE ++I+TLNN+FASFIDKVRFLEQQNKVL
Sbjct: 167 PGGIQEVTINQSLLQPLNVEIDPQIGQVKAQEREQIKTLNNKFASFIDKVRFLEQQNKVL 226

Query: 140 ETKWHLLQQQGLSG--SQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEY 197
           ETKW+LLQQQG S       LEP+FE  ++ LR  L+ + GERG LD+ELK   D  E++
Sbjct: 227 ETKWNLLQQQGTSSISGTNNLEPLFENHINYLRSYLDNILGERGRLDSELKNMEDLVEDF 286

Query: 198 KSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQL 257
           K KYE+E ++R   EN+FV LKKDVD  +++K+EL+ K++AL + + FL+ L + EL Q+
Sbjct: 287 KKKYEDEINKRTAAENEFVTLKKDVDSAYMNKVELQAKVDALIDEIDFLRTLYDAELSQM 346

Query: 258 QTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQL 317
           Q+  SDTSVVLSMDNNR LD  SII EVRA+YE+IA+ SKAEAEALYQTK  ELQ +A  
Sbjct: 347 QSHISDTSVVLSMDNNRSLDLDSIIAEVRAQYEDIAQRSKAEAEALYQTKLGELQTTAGR 406

Query: 318 HGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDE 377
           HGD ++ TK +I +L++ IQRL+++ E +KKQNA+LQ AI +AEQ GE+ALKDA AK+ E
Sbjct: 407 HGDDLRNTKSEIIELNRMIQRLRAEIEGVKKQNANLQTAIAEAEQHGEMALKDANAKLQE 466

Query: 378 LEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQVTISSV 437
           L+AAL+ AK +LARLL +YQEL + KL+LDVEIATYR+LLEGEE RMSGEC S V+IS V
Sbjct: 467 LQAALQQAKDDLARLLRDYQELMNVKLALDVEIATYRKLLEGEEYRMSGECPSAVSISVV 526

Query: 438 GGSAVMS------GGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILG 481
             S   +      GG GGG+G   GLG G  + G   +    GG   I G
Sbjct: 527 SSSTTSASAGGYGGGYGGGMGG--GLGGGFSAGGGSGSGFGRGGGGGIGG 574


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  459 bits (1181), Expect = e-129
 Identities = 263/509 (51%), Positives = 343/509 (67%), Gaps = 32/509 (6%)

Query: 11  GFSARSACSARSRGRSRGGFSSR----GGFSSRSLNSFGGCLEGSRGSTWGS-----GGR 61
           GFS  SA  +   G S   F +R      F S+SL+    CL GSR     +     GGR
Sbjct: 15  GFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLS----CLGGSRSLALSAAARRGGGR 70

Query: 62  LGVRFGEWSGGPGL-----SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIR 116
           LG   G   G  GL     S+CPPGGI +VT+N++LL PL +E+DP+ Q VR QE ++I+
Sbjct: 71  LGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130

Query: 117 TLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQL 176
            LNN+FASFIDKVRFLEQQN+VLETKW+LLQQ  L+  ++ LEP++E  +  L+KQLE L
Sbjct: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190

Query: 177 QGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKL 236
            G+   LD+EL+  +D  E+YK +YE E +RR   EN+FVVLKKDVD  +++K+EL+ K+
Sbjct: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250

Query: 237 EALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSS 296
           ++L + + F K L E E+ Q+Q+  SDTS+VLSMDNNR LD  SII EVRA+YEEIA  S
Sbjct: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310

Query: 297 KAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAA 356
           KAEAE LYQTK QELQV+A  HGD ++ TK +IS+L++ IQR++S+  N+KKQ A L+ A
Sbjct: 311 KAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETA 370

Query: 357 ITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRL 416
           I DAEQRG+ ALKDA+AK+DELE AL  AK+ LAR+L EYQEL S KL+LD+EIATYR+L
Sbjct: 371 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 430

Query: 417 LEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGS 476
           LE EECRMSGE  + V+IS +  +   +GG G  +G      S   S  +    + T GS
Sbjct: 431 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFG---ASSSYSYKTAAADVKTKGS 487

Query: 477 NIILGSG-KDPVLDSCSVSGSSAGSSCHT 504
               GS  KDP+         ++GSSC T
Sbjct: 488 ---CGSELKDPL-------AKTSGSSCAT 506


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  459 bits (1181), Expect = e-129
 Identities = 263/509 (51%), Positives = 343/509 (67%), Gaps = 32/509 (6%)

Query: 11  GFSARSACSARSRGRSRGGFSSR----GGFSSRSLNSFGGCLEGSRGSTWGS-----GGR 61
           GFS  SA  +   G S   F +R      F S+SL+    CL GSR     +     GGR
Sbjct: 15  GFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLS----CLGGSRSLALSAAARRGGGR 70

Query: 62  LGVRFGEWSGGPGL-----SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIR 116
           LG   G   G  GL     S+CPPGGI +VT+N++LL PL +E+DP+ Q VR QE ++I+
Sbjct: 71  LGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130

Query: 117 TLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQL 176
            LNN+FASFIDKVRFLEQQN+VLETKW+LLQQ  L+  ++ LEP++E  +  L+KQLE L
Sbjct: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190

Query: 177 QGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKL 236
            G+   LD+EL+  +D  E+YK +YE E +RR   EN+FVVLKKDVD  +++K+EL+ K+
Sbjct: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250

Query: 237 EALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSS 296
           ++L + + F K L E E+ Q+Q+  SDTS+VLSMDNNR LD  SII EVRA+YEEIA  S
Sbjct: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310

Query: 297 KAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAA 356
           KAEAE LYQTK QELQV+A  HGD ++ TK +IS+L++ IQR++S+  N+KKQ A L+ A
Sbjct: 311 KAEAETLYQTKIQELQVTAGQHGDDLKLTKAEISELNRLIQRIRSEIGNVKKQCADLETA 370

Query: 357 ITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRL 416
           I DAEQRG+ ALKDA+AK+DELE AL  AK+ LAR+L EYQEL S KL+LD+EIATYR+L
Sbjct: 371 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 430

Query: 417 LEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGS 476
           LE EECRMSGE  + V+IS +  +   +GG G  +G      S   S  +    + T GS
Sbjct: 431 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFG---ASSSYSYKTAAADVKTKGS 487

Query: 477 NIILGSG-KDPVLDSCSVSGSSAGSSCHT 504
               GS  KDP+         ++GSSC T
Sbjct: 488 ---CGSELKDPL-------AKTSGSSCAT 506


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  457 bits (1175), Expect = e-128
 Identities = 257/501 (51%), Positives = 333/501 (66%), Gaps = 25/501 (4%)

Query: 4   SPCRAQRGFSARSACSARSRGRSRGGFSS-----RGGFSSRSLNSFGGCLEGSRGSTWGS 58
           S   A+ GFS    CSA   G S   F +      GGF SRSL S GG    +  S  G 
Sbjct: 9   SGAAAKGGFSG---CSAVLSGGSSSSFRAGSKGLSGGFGSRSLYSLGGVRSLNVASGSGK 65

Query: 59  GGRLGVRFGEWSGGPGL------------SLCPPGGIQEVTINQNLLTPLKIEIDPQFQV 106
            G  G   G  SG  G             ++CPPGGI +VT+N++LL PL +E+DP+ Q 
Sbjct: 66  SGGYGFGRGRASGFAGSMFGSVALGPVCPTVCPPGGIHQVTVNESLLAPLNVELDPEIQK 125

Query: 107 VRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACL 166
           VR QE ++I+ LNN+FASFIDKVRFLEQQN+VLETKW LLQQ  L+  +  LEP+ E  +
Sbjct: 126 VRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKNNLEPILEGYI 185

Query: 167 DQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVF 226
             LRKQLE L G+R  LD+EL+  RD  E+YK +YEEE ++R   EN+FV+LKKDVD  +
Sbjct: 186 SNLRKQLETLSGDRVRLDSELRNVRDVVEDYKKRYEEEINKRTAAENEFVLLKKDVDAAY 245

Query: 227 LSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVR 286
            +K+EL+ K+E++ + + F + L E E+ Q+Q+  SD SV+LSMDNNR LD  SII EVR
Sbjct: 246 ANKVELQAKVESMDQEIKFFRCLFEAEITQIQSHISDMSVILSMDNNRNLDLDSIIDEVR 305

Query: 287 ARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENL 346
            +YEEIA  SKAEAEALYQTK+QELQ++A  HGD ++ TK +IS+L + IQR++S+ EN+
Sbjct: 306 TQYEEIALKSKAEAEALYQTKFQELQLAAGRHGDDLKNTKNEISELTRLIQRIRSEIENV 365

Query: 347 KKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSL 406
           KKQ ++L+ AI DAEQRG+ ALKDA+AK+DELE AL  AK+ LAR+L EYQEL S KL+L
Sbjct: 366 KKQASNLETAIADAEQRGDNALKDARAKLDELEGALHQAKEELARMLREYQELMSLKLAL 425

Query: 407 DVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGS 466
           D+EIATYR+LLE EECRMSGE  S V+IS +  +   SGG   G   +   G    +  +
Sbjct: 426 DMEIATYRKLLESEECRMSGEFPSPVSISIISST---SGGSVYGFRPSMVSGGYVANSSN 482

Query: 467 CCTSI--VTGGSNIILGSGKD 485
           C + +  V GG     GS  D
Sbjct: 483 CISGVCSVRGGEGRSRGSAND 503


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  456 bits (1173), Expect = e-128
 Identities = 259/494 (52%), Positives = 330/494 (66%), Gaps = 31/494 (6%)

Query: 12  FSARSACSARSRGRSRGGFSSRG-----GFSSRSLNSFGGCLEGS--------------- 51
           FS  SA   R    S   + + G     GF SRSL S GG    S               
Sbjct: 16  FSVHSAVVPRKAVGSLASYCAAGRGAGAGFGSRSLYSLGGNRRISFNVAGGGVRAGGYGF 75

Query: 52  -RGSTWGSG---GRLGVRFGEWSGGPG-LSLCPPGGIQEVTINQNLLTPLKIEIDPQFQV 106
             GS +G G   G  G  FG  + GP  LS+CPPGGI +VT+N++LL PL +E+DP+ Q 
Sbjct: 76  RPGSGYGGGRASGFAGSMFGSVALGPACLSVCPPGGIHQVTVNKSLLAPLNVELDPEIQK 135

Query: 107 VRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACL 166
           VR QE ++I+ LN++FASFIDKVRFLEQQN+VLETKW LLQQ  L+  ++ LEP+ E  +
Sbjct: 136 VRAQEREQIKVLNDKFASFIDKVRFLEQQNQVLETKWELLQQLDLNNCKKNLEPILEGYI 195

Query: 167 DQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVF 226
             LRKQLE L G+R  LD+EL++ RD  E+YK +YE E +RR T EN+FVVLKKD D  +
Sbjct: 196 SNLRKQLETLSGDRVRLDSELRSMRDLVEDYKKRYEVEINRRTTAENEFVVLKKDADAAY 255

Query: 227 LSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVR 286
             K+EL+ K+++L + + FLK L + E+ Q+QT AS+TSV+LSMDNNR LD  SII EVR
Sbjct: 256 AVKVELQAKVDSLDKEIKFLKCLYDAEIAQIQTHASETSVILSMDNNRDLDLDSIIAEVR 315

Query: 287 ARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENL 346
             YEEIA  SKAEAEALYQTK QELQ++A  HGD ++ T+ ++ +L++ IQR++ +  N+
Sbjct: 316 MHYEEIALKSKAEAEALYQTKIQELQLAASRHGDDLKHTRSEMVELNRLIQRIRCEIGNV 375

Query: 347 KKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSL 406
           KKQ ASL+ AI DAEQRG+ ALKDAQAK+DELE AL  AK+ LAR+L EYQEL S KL+L
Sbjct: 376 KKQRASLETAIADAEQRGDNALKDAQAKLDELEGALHQAKEELARMLREYQELMSLKLAL 435

Query: 407 DVEIATYRRLLEGEECRMSGECTSQVTISSVGGSAV-----MSGGVGGGLGSTCGLGSGK 461
           D+EIATYR+LLEGEECRMSGE  S V+IS +  S+       S GV  G  +  G  SG 
Sbjct: 436 DMEIATYRKLLEGEECRMSGENPSSVSISVISSSSYSYHHPSSAGVDLGASAVAG-SSGS 494

Query: 462 GSPGSCCTSIVTGG 475
              G   T+   GG
Sbjct: 495 TQSGQTKTTEARGG 508


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  437 bits (1123), Expect = e-122
 Identities = 253/507 (49%), Positives = 330/507 (65%), Gaps = 32/507 (6%)

Query: 10  RGFSARS--------ACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGST----WG 57
           RGF +RS        + S    GRS  GF   GG     +  FGG      GST    +G
Sbjct: 54  RGFGSRSLYNLGGSRSISINLMGRSTSGFCQGGG-----VGGFGGGRGFGVGSTGAGGFG 108

Query: 58  SGGRLGVRFGEWSGGPGL--SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEI 115
            GG  G  FG  + G G     CPPGGIQEVTINQ+LL PL +E+DP+ Q ++TQE ++I
Sbjct: 109 GGGFGGAGFGTSNFGLGGFGPYCPPGGIQEVTINQSLLEPLHLEVDPEIQRIKTQEREQI 168

Query: 116 RTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQ 175
             LNN+FASFIDKVRFLEQQN+VL+TKW LLQQ   S     LEP+ E  +  LR+Q++ 
Sbjct: 169 MVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNLEPLLENYIGDLRRQVDL 228

Query: 176 LQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGK 235
           L  E+   +AE+++ +D  E+YKSKYE+E ++R   ENDFVVLKKDVD  ++SK++LE +
Sbjct: 229 LSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVLKKDVDAAYVSKVDLESR 288

Query: 236 LEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARS 295
           ++ L   + FLK+L   EL Q+QT  SDT+V+LSMDNNR LD  SII  VR +YE IA+ 
Sbjct: 289 VDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDLDSIIDAVRTQYELIAQR 348

Query: 296 SKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQA 355
           SK EAEALYQTKYQELQ++A  HGD ++ +K++I++L++ +QRLQ++  N+KKQ   +Q+
Sbjct: 349 SKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQRLQAEISNVKKQIEQMQS 408

Query: 356 AITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRR 415
            I+DAE+RGE AL+DA  K+ +LE AL+ +K+ LARLL +YQ +   KLSLDVEIATYR+
Sbjct: 409 LISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQAMLGVKLSLDVEIATYRQ 468

Query: 416 LLEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGG 475
           LLEGEE RMSGE  S V+IS       ++GG GGG GS    G G GS G        GG
Sbjct: 469 LLEGEESRMSGELQSHVSISVQNSQVSVNGGAGGG-GSYGSGGYGGGSGGG------YGG 521

Query: 476 SNIILGSGKDPVLDSCSVSGSSAGSSC 502
                G G      +   SG   GS C
Sbjct: 522 GRSYRGGG------ARGRSGGGYGSGC 542


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  433 bits (1114), Expect = e-121
 Identities = 246/501 (49%), Positives = 329/501 (65%), Gaps = 30/501 (5%)

Query: 28  GGFSSRGGFSSRSL-----NSFGGCLEGSRGSTWGSGGRLGVRFGEWSG--------GPG 74
           GGF + GGF  R       +SFGG   G  G  +G GG  G RFG + G        GPG
Sbjct: 81  GGFGAAGGFGGRGGGFGGGSSFGGG-SGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPG 139

Query: 75  LSLCP---PGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRF 131
               P   PGGI EV++NQ+LL PL +++DP+ Q V+ QE ++I+TLNN+FASFIDKVRF
Sbjct: 140 -GFGPGGYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRF 198

Query: 132 LEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACR 191
           LEQQN+VL+TKW LLQQ  +      LEP+F+  +D L++ L+ L  ER + ++EL   +
Sbjct: 199 LEQQNQVLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQ 258

Query: 192 DQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNE 251
           D  E+YK KYE+E ++R   ENDFV LKKDVD  ++ K+EL+ K++ L + + FLK L +
Sbjct: 259 DLVEDYKKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYD 318

Query: 252 EELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQEL 311
            E+ Q+    +DT+V+LSMDN+R LD  SII EV+A+YEEIA+ SK EAEALY +KY+EL
Sbjct: 319 AEISQIHQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEEL 378

Query: 312 QVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDA 371
           QV+   HGD ++E K++IS+L++ IQRLQ +  ++KKQ  ++Q AI DAEQRGE ALKDA
Sbjct: 379 QVTVGRHGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDA 438

Query: 372 QAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQ 431
           + K+++LE AL+ AK++LARLL +YQEL + KL+LDVEIATYR+LLEGEECRMSG+ +S 
Sbjct: 439 RNKLNDLEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSN 498

Query: 432 VTI--------SSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGS----CCTSIVTGGSNII 479
           VT+        S+V   A   G  G G  S  G  SG  S GS      +   +GG   I
Sbjct: 499 VTVSVTSSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSI 558

Query: 480 LGSGKDPVLDSCSVSGSSAGS 500
            G G      S    GS  GS
Sbjct: 559 SGGGYGSGGGSGGRYGSGGGS 579


>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  420 bits (1080), Expect = e-117
 Identities = 237/448 (52%), Positives = 317/448 (70%), Gaps = 23/448 (5%)

Query: 12  FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71
           F++RSA  +    + R   +  GG  S SL   G            S  R+ VR     G
Sbjct: 10  FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGA-----------SRPRVAVRSAY--G 56

Query: 72  GPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRF 131
           GP        GI+EVTINQ+LL PL+++ DP  Q VR +E+++I+TLNN+FASFIDKVRF
Sbjct: 57  GP-----VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRF 111

Query: 132 LEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACR 191
           LEQQNK+LETKW LLQ+Q  + S + L  +FEA +  LR QLE LQ + G L+AEL++ +
Sbjct: 112 LEQQNKLLETKWTLLQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQ 170

Query: 192 DQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNE 251
           D  E++K+KYE+E + R   EN+FVVLKKDVD  ++SK+ELE K++AL + + FL+ LNE
Sbjct: 171 DVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNE 230

Query: 252 EELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQEL 311
            EL +LQ+Q SDTSVVLSMDN+R LD   II EV+A+YEE+A+ S+AEAEA YQTK++ L
Sbjct: 231 TELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETL 290

Query: 312 QVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDA 371
           Q  A  HGD ++ T+ +IS++++ IQRLQ++ +N+K Q A L+AAI +AE+RGELALKDA
Sbjct: 291 QAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDA 350

Query: 372 QAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQ 431
           +AK +ELEAAL+  KQ++AR L EYQEL S KL+LD+EIATYR+LLEGEE R++G+    
Sbjct: 351 RAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGA 410

Query: 432 VTIS---SVGGSAVMSGGVGGGLGSTCG 456
           V IS   S GGS+   GG+G  LG T G
Sbjct: 411 VNISVMNSTGGSS-SGGGIGLTLGGTMG 437


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  413 bits (1062), Expect = e-115
 Identities = 231/439 (52%), Positives = 310/439 (70%), Gaps = 18/439 (4%)

Query: 36  FSSRSLNSFGGC-LEGSRGSTWGSGGRLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLT 94
           FSSRS  S  G  +  S  S  GS    G   G + G  G+     GGI  VT+NQ+LL+
Sbjct: 20  FSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGM-----GGITAVTVNQSLLS 74

Query: 95  PLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGS 154
           PL +E+DP  Q VRTQE ++I+TLNN+FASFIDKVRFLEQQNK+LETKW LLQQQ  + S
Sbjct: 75  PLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARS 134

Query: 155 QQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLEND 214
              ++ +FE+ ++ LR+QLE L  E+  L+AEL   +   E++K+KYE+E ++R  +EN+
Sbjct: 135 N--MDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENE 192

Query: 215 FVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNR 274
           FV++KKDVD  +++K+ELE +LE L + + FL+ L EEE+ +LQ+Q SDTSVVLSMDN+R
Sbjct: 193 FVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSR 252

Query: 275 YLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQ 334
            LD  SII EV+A+YE+IA  S+AEAE++YQ KY+ELQ  A  HGD ++ TK +IS++++
Sbjct: 253 SLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNR 312

Query: 335 EIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLC 394
            I RLQ++ E LK Q ASL+AAI DAEQRGELA+KDA AK+ ELEAAL+ AKQ++AR L 
Sbjct: 313 NISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLR 372

Query: 395 EYQELTSTKLSLDVEIATYRRLLEGEECRM-SGECTSQVTISSVGGSA---------VMS 444
           EYQEL + KL+LD+EIATYR+LLEGEE R+ SG     +   +  G A         + S
Sbjct: 373 EYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTS 432

Query: 445 GGVGGGLGSTCGLGSGKGS 463
            G+   LGS+ G G+G  S
Sbjct: 433 PGLSYSLGSSFGSGAGSSS 451


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  397 bits (1021), Expect = e-110
 Identities = 241/509 (47%), Positives = 310/509 (60%), Gaps = 74/509 (14%)

Query: 11  GFSARSACSARSRGRSRGGFSSR----GGFSSRSLNSFGGCLEGSRGSTWGS-----GGR 61
           GFS  SA  +   G S   F +R      F S+SL+    CL GSR     +     GGR
Sbjct: 15  GFSGCSAVLSGGIGSSSASFRARVKGSASFGSKSLS----CLGGSRSLALSAAARRGGGR 70

Query: 62  LGVRFGEWSGGPGL-----SLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIR 116
           LG   G   G  GL     S+CPPGGI +VT+N++LL PL +E+DP+ Q VR QE ++I+
Sbjct: 71  LGGFVGTAFGSAGLGPKCPSVCPPGGIPQVTVNKSLLAPLNVEMDPEIQRVRAQEREQIK 130

Query: 117 TLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQL 176
            LNN+FASFIDKVRFLEQQN+VLETKW+LLQQ  L+  ++ LEP++E  +  L+KQLE L
Sbjct: 131 ALNNKFASFIDKVRFLEQQNQVLETKWNLLQQLDLNNCRKNLEPIYEGYISNLQKQLEML 190

Query: 177 QGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKL 236
            G+   LD+EL+  +D  E+YK +YE E +RR   EN+FVVLKKDVD  +++K+EL+ K+
Sbjct: 191 SGDGVRLDSELRNMQDLVEDYKKRYEVEINRRTAAENEFVVLKKDVDAAYMNKVELQAKV 250

Query: 237 EALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSS 296
           ++L + + F K L E E+ Q+Q+  SDTS+VLSMDNNR LD  SII EVRA+YEEIA  S
Sbjct: 251 DSLTDEIKFFKCLYEGEITQIQSHISDTSIVLSMDNNRDLDLDSIIAEVRAQYEEIALKS 310

Query: 297 KAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAA 356
           KAEAE LYQTK                                           A L+ A
Sbjct: 311 KAEAETLYQTKC------------------------------------------ADLETA 328

Query: 357 ITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRL 416
           I DAEQRG+ ALKDA+AK+DELE AL  AK+ LAR+L EYQEL S KL+LD+EIATYR+L
Sbjct: 329 IADAEQRGDCALKDARAKLDELEGALHQAKEELARMLREYQELVSLKLALDMEIATYRKL 388

Query: 417 LEGEECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGS 476
           LE EECRMSGE  + V+IS +  +   +GG G  +G      S   S  +    + T GS
Sbjct: 389 LESEECRMSGEYPNSVSISVISSTNAGAGGAGFSMGFG---ASSSYSYKTAAADVKTKGS 445

Query: 477 NIILGSG-KDPVLDSCSVSGSSAGSSCHT 504
               GS  KDP+         ++GSSC T
Sbjct: 446 ---CGSELKDPL-------AKTSGSSCAT 464


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  371 bits (953), Expect = e-103
 Identities = 238/542 (43%), Positives = 322/542 (59%), Gaps = 56/542 (10%)

Query: 12  FSARSACSARSRGRSRG---------GFSSRGGFSSRSLNSFGG-----CLEGSR----G 53
           FS+ SA + ++  R R          GF   G F SRS+ +FG         GSR    G
Sbjct: 17  FSSCSAMTPQNLNRFRANSVSCWSGPGFRGLGSFGSRSVITFGSYSPRIAAVGSRPIHCG 76

Query: 54  STWGSG-------GR-----------LGVRFGEWS------GGPGLSLCPPG-------G 82
             +G+G       GR           +G+ FG  S      GGPG      G        
Sbjct: 77  VRFGAGCGMGFGDGRGVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPS 136

Query: 83  IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRFLEQQNKVLETK 142
           I  VT+N++LLTPL +EIDP  Q V+  E ++I+TLNN+FASFIDKVRFLEQQNK+LETK
Sbjct: 137 ITAVTVNKSLLTPLNLEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETK 196

Query: 143 WHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACRDQEEEYKSKYE 202
           W  LQ+Q    S   LEP+FE+ +  LR+QLE L  ++  L AE    +D  E +K KYE
Sbjct: 197 WSFLQEQKCIRS--NLEPLFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYE 254

Query: 203 EEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNEEELGQLQTQAS 262
           EE   RA  EN+FV LKKDVD  F++K +LE  ++ L + + FLK L  EE+  LQ+  S
Sbjct: 255 EEVVCRANAENEFVALKKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHIS 314

Query: 263 DTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQELQVSAQLHGDRM 322
           +TSV++ MDN+R L+   II EV+A+YEE+AR S+A+AEA YQTKY+E+QV+A  H D +
Sbjct: 315 ETSVIVKMDNSRDLNLDGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNL 374

Query: 323 QETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDAQAKVDELEAAL 382
           +  + +I++L + IQRL+++ E+ K Q A L+AA+ +AEQ+GE  L DA+ K+ +LE AL
Sbjct: 375 RNIRNEINELTRLIQRLKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECAL 434

Query: 383 RMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGECTSQVTISSVGGSA 441
           + AKQ++AR LCEYQEL + KL LD+EIATYRRLLEGEE R+  G     +++SS  G  
Sbjct: 435 QQAKQDMARQLCEYQELMNAKLGLDIEIATYRRLLEGEESRLCEGVGPVNISVSSSRGGL 494

Query: 442 VMSGGVGGGLGSTCGLG--SGKGSPGSCCTSIVTGGSNIILGSGK-DPVLDSCSVSGSSA 498
           V  G      GST   G  +  GS   C TS V       LG  +  P       +G+ +
Sbjct: 495 V-CGPEPLVAGSTLSRGGVTFSGSSSVCATSGVLASCGPSLGGARVAPATGDLLSTGTRS 553

Query: 499 GS 500
           GS
Sbjct: 554 GS 555


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  367 bits (942), Expect = e-101
 Identities = 230/516 (44%), Positives = 319/516 (61%), Gaps = 42/516 (8%)

Query: 4   SPCRAQRGFSARSACSARSRGRS-------RGGFSSRG--GFSSRSLNSFGGCLEGSRGS 54
           S C   R FS+ SA + ++  R        RG    RG  GF SRSL + G C  G R +
Sbjct: 10  SGCGVTRNFSSCSAVAPKTGNRCCISAAPYRGVSCYRGLTGFGSRSLCNLGSC--GPRIA 67

Query: 55  TWG-SGGRLGVRFGEWSGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQE 111
             G   G  G  FG  SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E
Sbjct: 68  VGGFRAGSCGRSFGYRSGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEE 123

Query: 112 TQEIRTLNNQFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRK 171
            ++I++LN++FA+FIDKVRFLEQQNK+LETKW   Q Q     +  LEP+F   ++ LR+
Sbjct: 124 KEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRC--CESNLEPLFSGYIETLRR 181

Query: 172 QLEQLQGERGALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKME 231
           + E ++ + G L +EL   ++  E YK KYEEE   RAT EN+FVVLKKDVD  +L K +
Sbjct: 182 EAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVLKKDVDCAYLRKSD 241

Query: 232 LEGKLEALREYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEE 291
           LE  +EAL E   FL+ L EEE+  LQ   SDTSV++ MDN+R L+   II E++A+Y++
Sbjct: 242 LEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNMDCIIAEIKAQYDD 301

Query: 292 IARSSKAEAEALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNA 351
           +A  S+AEAE+ Y++K +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K Q A
Sbjct: 302 VASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEIENAKCQRA 361

Query: 352 SLQAAITDAEQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIA 411
            L+AA+ +AEQ+GE AL DA+ K+ ELE AL+ AKQ++A LL EYQE+ ++KL LD+EIA
Sbjct: 362 KLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQEVMNSKLGLDIEIA 421

Query: 412 TYRRLLEGEECRM-SGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTS 470
           TYRRLLEGEE R+  G  +  V +SS  G            G +CG  S   +PG     
Sbjct: 422 TYRRLLEGEEHRLCEGVGSVNVCVSSSRG------------GVSCGGLSYSTTPG----R 465

Query: 471 IVTGGSNIILGSGKDPVLDSCS-----VSGSSAGSS 501
            +T G + I GS      DSC+      S  S GSS
Sbjct: 466 QITSGPSAIGGSITVVAPDSCAPCQPRSSSFSCGSS 501


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  354 bits (909), Expect = 9e-98
 Identities = 219/484 (45%), Positives = 296/484 (61%), Gaps = 37/484 (7%)

Query: 1   MSLSPCRAQRGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGG 60
           +S  PCR   G   R+     SR     GF        R  +  GG L G        G 
Sbjct: 33  VSKGPCRPGGGRGLRALGCLGSRSLCNVGFGR-----PRVASRCGGTLPGF-------GY 80

Query: 61  RLGVRFGEWSGGPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNN 120
           RLG   G           P   I  VTIN++LL PL +EIDP  Q V+  E ++I+ LNN
Sbjct: 81  RLGATCG-----------PSACITPVTINESLLVPLALEIDPTVQRVKRDEKEQIKCLNN 129

Query: 121 QFASFIDKVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGER 180
           +FASFI+KVRFLEQ+NK+LETKW+ +QQQ     Q  +EP+FE  +  LR+QL+ + G+R
Sbjct: 130 RFASFINKVRFLEQKNKLLETKWNFMQQQRCC--QTNIEPIFEGYISALRRQLDCVSGDR 187

Query: 181 GALDAELKACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALR 240
             L++EL + +   E YK KYEEE   R  +EN+FV LKKDVD  FL K +LE   EAL 
Sbjct: 188 VRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADLETNAEALV 247

Query: 241 EYLYFLKHLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEA 300
           + + FLK L EEE+  LQ+Q S+TSV++ MDN+R LD   II E++A+Y++IA  SKAEA
Sbjct: 248 QEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDIASRSKAEA 307

Query: 301 EALYQTKYQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDA 360
           EA YQ +Y+EL+V+A  H D ++  K +I ++++ IQRLQ +TEN+K Q   L+ AI +A
Sbjct: 308 EAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCKLEGAIAEA 367

Query: 361 EQRGELALKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGE 420
           EQ+GE AL DA+ K+  LE AL+ AKQ++A LL EYQE+ ++KL LD+EIATYRRLLEGE
Sbjct: 368 EQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIATYRRLLEGE 427

Query: 421 ECRMSGECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIIL 480
           E R+  E    V IS       +S   G  L   CG+ +   S G     + + G   I+
Sbjct: 428 EHRLC-EGIGPVNIS-------VSSSKGAFLYEPCGVSTPVLSTG----VLRSNGGCSIV 475

Query: 481 GSGK 484
           G+G+
Sbjct: 476 GTGE 479


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  349 bits (896), Expect = 3e-96
 Identities = 221/506 (43%), Positives = 304/506 (60%), Gaps = 26/506 (5%)

Query: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66

Query: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 241 RLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 427 ECTSQVTISSVGGSAVMS----GGVGGGLGSTCGL---GSGKGSPGSCCTSIVTGGSNII 479
                V +SS  G  V       G     GS C     G+   S G C      G  N  
Sbjct: 421 IGAVNVCVSSSRGGVVCGDLCVSGSRPVTGSVCSAPCNGNVAVSTGLCAP---CGQLNTT 477

Query: 480 LGSGKDPVLDSCSVSG---SSAGSSC 502
            G G   V  SC +S     S GSSC
Sbjct: 478 CGGGSCGV-GSCGISSLGVGSCGSSC 502


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  346 bits (887), Expect = 3e-95
 Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)

Query: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66

Query: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486
             +  V +SS  G  V         G  C   S      S   S V   SN+++G+    
Sbjct: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466

Query: 487 VLDSCSVSG--SSAGSSC 502
             ++C+ S      G SC
Sbjct: 467 -TNACAPSARVGVCGGSC 483


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  346 bits (887), Expect = 3e-95
 Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)

Query: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66

Query: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486
             +  V +SS  G  V         G  C   S      S   S V   SN+++G+    
Sbjct: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466

Query: 487 VLDSCSVSG--SSAGSSC 502
             ++C+ S      G SC
Sbjct: 467 -TNACAPSARVGVCGGSC 483


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  346 bits (887), Expect = 3e-95
 Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)

Query: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66

Query: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486
             +  V +SS  G  V         G  C   S      S   S V   SN+++G+    
Sbjct: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466

Query: 487 VLDSCSVSG--SSAGSSC 502
             ++C+ S      G SC
Sbjct: 467 -TNACAPSARVGVCGGSC 483


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  346 bits (887), Expect = 3e-95
 Identities = 214/498 (42%), Positives = 303/498 (60%), Gaps = 29/498 (5%)

Query: 10  RGFSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEW 69
           R FS  SAC  R           RG    R L    G      G   GS GR    FG  
Sbjct: 10  RAFSCISACGPRPGRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYR 66

Query: 70  SGGPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFID 127
           SGG    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FID
Sbjct: 67  SGG----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFID 122

Query: 128 KVRFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAEL 187
           KVRFLEQQNK+LETK    Q +     Q  LEP+FE  ++ LR++ E ++ + G L +EL
Sbjct: 123 KVRFLEQQNKLLETKLQFYQNRECC--QSNLEPLFEGYIETLRREAECVEADSGRLASEL 180

Query: 188 KACRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLK 247
              ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+
Sbjct: 181 NHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLR 240

Query: 248 HLNEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTK 307
            L EEE+  LQ+  SDTSVV+ +DN+R L+   II E++A+Y++I   S+AEAE+ Y++K
Sbjct: 241 RLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQYDDIVTRSRAEAESWYRSK 300

Query: 308 YQELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELA 367
            +E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE A
Sbjct: 301 CEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAA 360

Query: 368 LKDAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SG 426
           L DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G
Sbjct: 361 LSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEG 420

Query: 427 ECTSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDP 486
             +  V +SS  G  V         G  C   S      S   S V   SN+++G+    
Sbjct: 421 VGSVNVCVSSSRGGVV--------CGDLC--ASTTAPVVSTRVSSVPSNSNVVVGT---- 466

Query: 487 VLDSCSVSG--SSAGSSC 502
             ++C+ S      G SC
Sbjct: 467 -TNACAPSARVGVCGGSC 483


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  345 bits (885), Expect = 6e-95
 Identities = 212/495 (42%), Positives = 300/495 (60%), Gaps = 21/495 (4%)

Query: 12  FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71
           FS  SAC  R           RG    R L    G      G   GS GR    FG  SG
Sbjct: 17  FSCVSACGPRPSRCCITAAPYRGISCYRGLTGGFGSHSVCGGFRAGSCGR---SFGYRSG 73

Query: 72  GPGLSLCPPGG--IQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKV 129
           G    +C P    I  V++N++LLTPL +EIDP  Q V+ +E ++I++LN++FA+FIDKV
Sbjct: 74  G----VCGPSPPCITTVSVNESLLTPLNLEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKV 129

Query: 130 RFLEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKA 189
           RFLEQQNK+LETK    Q +     Q  LEP+F   ++ LR++ E ++ + G L +EL  
Sbjct: 130 RFLEQQNKLLETKLQFYQNRECC--QSNLEPLFAGYIETLRREAECVEADSGRLASELNH 187

Query: 190 CRDQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHL 249
            ++  E YK KYEEE   RAT EN+FV LKKDVD  +L K +LE  +EAL + + FL+ L
Sbjct: 188 VQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLRKSDLEANVEALIQEIDFLRRL 247

Query: 250 NEEELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQ 309
            EEE+  LQ+  SDTSVV+ +DN+R L+   I+ E++A+Y++IA  S+AEAE+ Y++K +
Sbjct: 248 YEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQYDDIATRSRAEAESWYRSKCE 307

Query: 310 ELQVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALK 369
           E++ +   HG+ ++ TK +I++L++ IQRL ++ EN K QN+ L+AA+  +EQ+GE AL 
Sbjct: 308 EMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKCQNSKLEAAVAQSEQQGEAALS 367

Query: 370 DAQAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRM-SGEC 428
           DA+ K+ ELE AL+ AKQ++A L+ EYQE+ ++KL LD+EIATYRRLLEGEE R+  G  
Sbjct: 368 DARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDIEIATYRRLLEGEEQRLCEGVE 427

Query: 429 TSQVTISSVGGSAVMSGGVGGGLGSTCGLGSGKGSPGSCCTSIVTGGSNIILGSGKDPVL 488
              V +SS  G  V         G  C  GS +   GS C++   G   +  G  K    
Sbjct: 428 AVNVCVSSSRGGVV--------CGDLCVSGS-RPVTGSVCSAPCNGNLVVSTGLCKPCGQ 478

Query: 489 DSCSVSGSSAGSSCH 503
            + +  G S G   H
Sbjct: 479 LNTTCGGGSCGQGRH 493


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.313    0.129    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,699,212
Number of Sequences: 37866
Number of extensions: 926953
Number of successful extensions: 9224
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 257
Number of HSP's successfully gapped in prelim test: 716
Number of HSP's that attempted gapping in prelim test: 5397
Number of HSP's gapped (non-prelim): 2885
length of query: 520
length of database: 18,247,518
effective HSP length: 107
effective length of query: 413
effective length of database: 14,195,856
effective search space: 5862888528
effective search space used: 5862888528
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.