Guide to the Human Genome
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Search of human proteins with 8923842

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|8923842 forkhead box J2 [Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|8923842 forkhead box J2 [Homo sapiens]                            1220   0.0  
gi|50345831 forkhead box J3 [Homo sapiens]                            346   3e-95
gi|4885237 forkhead box C2 [Homo sapiens]                             135   1e-31
gi|50301236 forkhead box J1 [Homo sapiens]                            125   1e-28
gi|208431824 forkhead box I3 [Homo sapiens]                           124   2e-28
gi|195947376 forkhead box I2 [Homo sapiens]                           123   5e-28
gi|21618327 forkhead box I1 isoform a [Homo sapiens]                  122   7e-28
gi|119395716 forkhead box C1 [Homo sapiens]                           121   2e-27
gi|22779860 forkhead box L1 [Homo sapiens]                            115   1e-25
gi|24497506 forkhead box A3 [Homo sapiens]                            114   2e-25
gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]                  111   2e-24
gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]                 111   2e-24
gi|24497501 forkhead box A1 [Homo sapiens]                            110   4e-24
gi|4557595 forkhead box F2 [Homo sapiens]                             110   4e-24
gi|32307177 forkhead box G1 [Homo sapiens]                            109   6e-24
gi|110735445 forkhead box F1 [Homo sapiens]                           109   8e-24
gi|134142824 forkhead box D2 [Homo sapiens]                           109   8e-24
gi|6912372 forkhead box D3 [Homo sapiens]                             107   2e-23
gi|12751477 forkhead box L2 [Homo sapiens]                            106   5e-23
gi|31563338 forkhead box K2 [Homo sapiens]                            106   7e-23
gi|21618325 forkhead box E1 [Homo sapiens]                            105   1e-22
gi|82546824 forkhead box K1 [Homo sapiens]                            104   2e-22
gi|28973785 forkhead box S1 [Homo sapiens]                            104   3e-22
gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]         103   6e-22
gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]          103   6e-22
gi|4758392 forkhead box D1 [Homo sapiens]                             102   7e-22
gi|105554437 forkhead box B1 [Homo sapiens]                           102   7e-22
gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]     102   1e-21
gi|169172132 PREDICTED: similar to forkhead box L2 [Homo sapiens]     102   1e-21
gi|113419423 PREDICTED: similar to forkhead box L2 [Homo sapiens]     102   1e-21

>gi|8923842 forkhead box J2 [Homo sapiens]
          Length = 574

 Score = 1220 bits (3156), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA 60
           MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA
Sbjct: 1   MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA 60

Query: 61  VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 120
           VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL
Sbjct: 61  VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 120

Query: 121 NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS 180
           NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS
Sbjct: 121 NKCFRKVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGS 180

Query: 181 GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK 240
           GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK
Sbjct: 181 GEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFK 240

Query: 241 FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ 300
           FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ
Sbjct: 241 FSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQ 300

Query: 301 QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP 360
           QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP
Sbjct: 301 QQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPP 360

Query: 361 PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS 420
           PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS
Sbjct: 361 PVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSNIDS 420

Query: 421 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV 480
           LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV
Sbjct: 421 LKESFKMVNRLNWSSIEQSQFSELMESLRQAEQKNWTLDQHHIANLCDSLNHFLTQTGHV 480

Query: 481 PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA 540
           PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA
Sbjct: 481 PPQGGTHRPPAPARIADSCALTSGKQESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSA 540

Query: 541 GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT 574
           GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT
Sbjct: 541 GYNRPAHHMVPRPSVPPPGANEEIPDDFDWDLIT 574


>gi|50345831 forkhead box J3 [Homo sapiens]
          Length = 622

 Score =  346 bits (888), Expect = 3e-95
 Identities = 247/676 (36%), Positives = 323/676 (47%), Gaps = 173/676 (25%)

Query: 1   MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA 60
           M S+LESSLTS+DWLPQLT+RA I+K  +   A   G S+K    +  DPN TL ++E  
Sbjct: 16  MTSELESSLTSMDWLPQLTMRAAIQKSDATQNAHGTGISKK---NALLDPNTTLDQEEVQ 72

Query: 61  VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 120
            H+DGKP YSYA+LIT+AINSSP KKMTLSEIY+WICDNFPYY+ AG GWKNSIRHNLSL
Sbjct: 73  QHKDGKPPYSYASLITFAINSSPKKKMTLSEIYQWICDNFPYYREAGSGWKNSIRHNLSL 132

Query: 121 NKCFRKVPRPRDDPGKGSYWTIDTCP--DI----------SRKRRHPP----DDDLSQD- 163
           NKCF KVPR +DDPGKGSYW IDT P  D+          S +R   P     D L  + 
Sbjct: 133 NKCFLKVPRSKDDPGKGSYWAIDTNPKEDVLPTRPKKRARSVERASTPYSIDSDSLGMEC 192

Query: 164 ----------------------SPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSI 201
                                 + +Q+ S SPR  +      SL  +    ++L S  S+
Sbjct: 193 IISGSASPTLAINTVTNKVTLYNTDQDGSDSPRSSL----NNSLSDQSLASVNLNSVGSV 248

Query: 202 ASYSQGTGSVDGGAVAAGASGRESAEGPPPLYN-TNHDFKFSYSEINFQDLSWSFRNLYK 260
            SY+  T   +  +V+   + ++      P YN    D +  +SE NF+DLS SFR+LYK
Sbjct: 249 HSYTPVTSHPE--SVSQSLTPQQQ-----PQYNLPERDKQLLFSEYNFEDLSASFRSLYK 301

Query: 261 SMLEKS-------------------SSSSQHGFSSLLGDIPPSN---------------- 285
           S+ E+S                   S + QH  SS +   P SN                
Sbjct: 302 SVFEQSLSQQGLMNIPSESSQQSHTSCTYQHSPSSTVSTHPHSNQSSLSNSHGSGLNTTG 361

Query: 286 ----------NYYMYQQQQPPPPQQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPP 335
                     +  M+ Q  P PP +     Q PQ  P  +   QQ +  Q P        
Sbjct: 362 SNSVAQVSLSHPQMHTQPSPHPPHRPHGLPQHPQRSPHPAPHPQQHSQLQSPH------- 414

Query: 336 LHTPSTDGCTPPGGKQAGAEGYGPPPVMAMHPPPLQHGGYHP-HQHHPHSHPAQQPPPPQ 394
                                         HP P QH  +HP HQH   +H  Q PPPPQ
Sbjct: 415 ----------------------------PQHPSPHQHIQHHPNHQHQTLTH--QAPPPPQ 444

Query: 395 PQAQGQAPINNTGFAFPSDWCSNIDSLKESFKMVNRLNWSSIEQSQFSELMESLRQAEQK 454
            Q    + ++N       DW + +D LKES ++ + +NWS ++ SQF  LMES+RQA+ K
Sbjct: 445 -QVSCNSGVSN-------DWYATLDMLKESCRIASSVNWSDVDLSQFQGLMESMRQADLK 496

Query: 455 NWTLDQHHIANLCDSLNHFLTQTGHVPPQG--------GTHRPPAPAR-IADSCALTSGK 505
           NW+LDQ   A+LC SLN F TQTG +  Q         G   P  P++ I         +
Sbjct: 497 NWSLDQVQFADLCSSLNQFFTQTGLIHSQSNVQQNVCHGAMHPTKPSQHIGTGNLYIDSR 556

Query: 506 QESAMSQVNSYGHPQAPHLYPGPSPMYPIPTQDSAGYNRPAH--HMVP------RPSVPP 557
           Q    S +   G+P  P     P           AG++R  +  HM+P      R S+PP
Sbjct: 557 QNLPPSVMPPPGYPHIPQALSTPG-------TTMAGHHRAMNQQHMMPSQAFQMRRSLPP 609

Query: 558 PGANEEIPDDFDWDLI 573
               ++I DDFDWD I
Sbjct: 610 ----DDIQDDFDWDSI 621


>gi|4885237 forkhead box C2 [Homo sapiens]
          Length = 501

 Score =  135 bits (340), Expect = 1e-31
 Identities = 121/420 (28%), Positives = 173/420 (41%), Gaps = 50/420 (11%)

Query: 29  SASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDG--------KPRYSYATLITYAIN 80
           +A   G   S      G P   +A + +  A  H           KP YSY  LIT AI 
Sbjct: 27  AAGSYGGMASPMGVYSGHPEQYSAGMGRSYAPYHHHQPAAPKDLVKPPYSYIALITMAIQ 86

Query: 81  SSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYW 140
           ++P KK+TL+ IY++I D FP+Y+    GW+NSIRHNLSLN+CF KVPR    PGKGSYW
Sbjct: 87  NAPEKKITLNGIYQFIMDRFPFYRENKQGWQNSIRHNLSLNECFVKVPRDDKKPGKGSYW 146

Query: 141 TIDTCPD---------ISRKRRHPPDDDLSQDSPEQEASKSP-----RGGVAGSGEASLP 186
           T+D  PD           R+RR     D+S++  E+   K P     +G  A    A  P
Sbjct: 147 TLD--PDSYNMFENGSFLRRRRRFKKKDVSKEKEERAHLKEPPPAASKGAPATPHLADAP 204

Query: 187 PEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFKFSYSEI 246
            E   ++ ++S  +  +    T  V+  +  +   G   +    P  + +      ++  
Sbjct: 205 KEAEKKVVIKSEAASPALPVIT-KVETLSPESALQGSPRSAASTPAGSPDGSLPEHHAAA 263

Query: 247 NFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQQQQQQQ 306
                 +S  N+   M  ++S           G++ P       +     PP        
Sbjct: 264 PNGLPGFSVENI---MTLRTSPPG--------GELSPGAG----RAGLVVPPLALPYAAA 308

Query: 307 PPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPS---TDGCTPPGGKQAGAEGYGPP--P 361
           PP    Q      +   A G      A  L+T +      C PP   +A ++    P  P
Sbjct: 309 PPAAYGQPCAQGLEAGAAGGYQCSMRAMSLYTGAERPAHMCVPPALDEALSDHPSGPTSP 368

Query: 362 VMAMHPPPLQHGGY----HPHQHHPHSHPAQQPPPPQPQAQGQAPINNTGFAFPSDWCSN 417
           + A++    Q G      H HQHH H HP   PPPP PQ Q   P      A  + W  N
Sbjct: 369 LSALNLAAGQEGALAATGHHHQHHGHHHPQAPPPPPAPQPQ-PTPQPGAAAAQAASWYLN 427


>gi|50301236 forkhead box J1 [Homo sapiens]
          Length = 421

 Score =  125 bits (313), Expect = 1e-28
 Identities = 85/248 (34%), Positives = 122/248 (49%), Gaps = 48/248 (19%)

Query: 5   LESSLTSIDWLPQLT-LRATIEKL--------------GSASQAGPPGSSRKC-----SP 44
           L+ SLTS+ WL + + L A    L              GSA+   P  +   C     +P
Sbjct: 29  LDDSLTSLQWLQEFSILNAKAPALPPGGTDPHGYHQVPGSAAPGSPLAADPACLGQPHTP 88

Query: 45  GSPTDPNATLSKD-----------EAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIY 93
           G PT    + S             + A +   KP YSYATLI  A+ +S A K+TLS IY
Sbjct: 89  GKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIY 148

Query: 94  RWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTID------TCPD 147
           +WI DNF Y+++A   W+NSIRHNLSLNKCF KVPR +D+PGKG +W ID          
Sbjct: 149 KWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSG 208

Query: 148 ISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQG 207
             +KRR PP       +  ++A++ P         +++P  G   ++ ++   +  + + 
Sbjct: 209 AFKKRRLPPVH--IHPAFARQAAQEP---------SAVPRAGPLTVNTEAQQLLREFEEA 257

Query: 208 TGSVDGGA 215
           TG    GA
Sbjct: 258 TGEAGWGA 265


>gi|208431824 forkhead box I3 [Homo sapiens]
          Length = 420

 Score =  124 bits (312), Expect = 2e-28
 Identities = 73/188 (38%), Positives = 104/188 (55%), Gaps = 16/188 (8%)

Query: 36  PGSSRKCSPGSPTDPNATLSKDEAAVHQD----GKPRYSYATLITYAINSSPAKKMTLSE 91
           P  +   SP +P  P   L     A  +D     +P YSY+ LI  AI S+P +K+TLS 
Sbjct: 112 PAPAAPASPAAPAGPGE-LGWLSMASREDLMKMVRPPYSYSALIAMAIQSAPERKLTLSH 170

Query: 92  IYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTID-TCPDI-- 148
           IY+++ D+FP+Y+ +  GW+NSIRHNLSLN CF+KVPR  DDPGKG+YWT+D  C  +  
Sbjct: 171 IYQFVADSFPFYQRSKAGWQNSIRHNLSLNDCFKKVPRDEDDPGKGNYWTLDPNCEKMFD 230

Query: 149 ------SRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIA 202
                  RKRR    +  +  +   ++ +    G+ GSG    P E +P  +L  P+   
Sbjct: 231 NGNFRRKRKRRSEASNGSTVAAGTSKSEEGLSSGL-GSGVGGKPEEESPS-TLLRPSHSP 288

Query: 203 SYSQGTGS 210
              +GT S
Sbjct: 289 EPPEGTKS 296



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 24/82 (29%), Positives = 27/82 (32%), Gaps = 10/82 (12%)

Query: 328 SAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPPVMAMHPPPLQHGGYHPHQHHPHSHPA 387
           S  G  PP  T +  G  P      G   Y  PP  A +P    +G   P    P S  A
Sbjct: 13  SQPGLPPPAATAAAPGAPPAARAPYGLADYAAPPAAAANPYLWLNG---PGVGGPPSAAA 69

Query: 388 Q-------QPPPPQPQAQGQAP 402
                    PPPP P      P
Sbjct: 70  AAAAAYLGAPPPPPPPGAAAGP 91


>gi|195947376 forkhead box I2 [Homo sapiens]
          Length = 318

 Score =  123 bits (308), Expect = 5e-28
 Identities = 70/168 (41%), Positives = 93/168 (55%), Gaps = 25/168 (14%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           +P YSY+ LI  AI S+P +K+TLS+IY+++  NFP+YK +  GW+NSIRHNLSLN CF+
Sbjct: 102 RPPYSYSALIAMAIQSAPLRKLTLSQIYQYVAGNFPFYKRSKAGWQNSIRHNLSLNDCFK 161

Query: 126 KVPRPRDDPGKGSYWTID-TCP------DISRKRRHPPDDDLSQDSPEQEASKSPRGGVA 178
           KVPR  DDPGKG+YWT+D  C       +  RKR+              EAS + R G  
Sbjct: 162 KVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKR-----------RAEASAAVRSGAR 210

Query: 179 GSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESA 226
             G A  P       +L+ P++     Q + S      A   SG  SA
Sbjct: 211 SVGGAEAP-------ALEPPSAACLDLQASPSPSAPEAATCFSGFASA 251


>gi|21618327 forkhead box I1 isoform a [Homo sapiens]
          Length = 378

 Score =  122 bits (307), Expect = 7e-28
 Identities = 67/171 (39%), Positives = 92/171 (53%), Gaps = 21/171 (12%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           +P YSY+ LI  AI+ +P K++TLS+IY+++ DNFP+Y  +  GW+NSIRHNLSLN CF+
Sbjct: 123 RPPYSYSALIAMAIHGAPDKRLTLSQIYQYVADNFPFYNKSKAGWQNSIRHNLSLNDCFK 182

Query: 126 KVPRPRDDPGKGSYWTID-TCP------DISRKRRHPPD--------------DDLSQDS 164
           KVPR  DDPGKG+YWT+D  C       +  RKR+   D                L  DS
Sbjct: 183 KVPRDEDDPGKGNYWTLDPNCEKMFDNGNFRRKRKRKSDVSSSTASLALEKTESSLPVDS 242

Query: 165 PEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGA 215
           P+    +    G +  G  S P +        +P   +  S  T  V GG+
Sbjct: 243 PKTTEPQDILDGASPGGTTSSPEKRPSPPPSGAPCLNSFLSSMTAYVSGGS 293


>gi|119395716 forkhead box C1 [Homo sapiens]
          Length = 553

 Score =  121 bits (304), Expect = 2e-27
 Identities = 108/340 (31%), Positives = 134/340 (39%), Gaps = 66/340 (19%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY  LIT AI ++P KK+TL+ IY++I D FP+Y++   GW+NSIRHNLSLN+CF 
Sbjct: 78  KPPYSYIALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFV 137

Query: 126 KVPRPRDDPGKGSYWTIDTCPD---------ISRKRRHPPDDDLSQDSPEQEASKSPRGG 176
           KVPR    PGKGSYWT+D  PD           R+RR     D  +D  E++        
Sbjct: 138 KVPRDDKKPGKGSYWTLD--PDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPP 195

Query: 177 VAGSGEASLPPE---GNPQMSLQSPTSIASYSQGTG---SVDGGAVAAGASGRESAEGPP 230
             G      PPE   GN       P  I       G   S       A A G  SA   P
Sbjct: 196 PPGRQPPPAPPEQADGNAPGPQPPPVRIQDIKTENGTCPSPPQPLSPAAALGSGSAAAVP 255

Query: 231 PLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMY 290
            + + +                             SSSSS    SS  G +P +    + 
Sbjct: 256 KIESPD-----------------------------SSSSSLSSGSSPPGSLPSARPLSLD 286

Query: 291 QQQQPPPPQQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLH-TPSTDGCTPPGG 349
                PPP        P  PPP  S         QG S       L  +P +       G
Sbjct: 287 GADSAPPP------PAPSAPPPHHS---------QGFSVDNIMTSLRGSPQSAAAELSSG 331

Query: 350 KQAGAEGYGPPPVMAMHPPPLQHGGYHPHQHHPHSHPAQQ 389
             A A       +     PPL  G Y P Q   +S P  Q
Sbjct: 332 LLASAAASSRAGI----APPLALGAYSPGQSSLYSSPCSQ 367


>gi|22779860 forkhead box L1 [Homo sapiens]
          Length = 345

 Score =  115 bits (287), Expect = 1e-25
 Identities = 65/166 (39%), Positives = 89/166 (53%), Gaps = 12/166 (7%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY  LI  AI  +P +++TL+ IY++I D FP+Y +   GW+NSIRHNLSLN CF 
Sbjct: 49  KPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFV 108

Query: 126 KVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASL 185
           KVPR +  PGKGSYWT+D           P   D+ ++   +   + P+ G  G+ EA  
Sbjct: 109 KVPREKGRPGKGSYWTLD-----------PRCLDMFENGNYRRRKRKPKPG-PGAPEAKR 156

Query: 186 PPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPP 231
           P     Q S ++     S + G+G       AA A      +GP P
Sbjct: 157 PRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSP 202


>gi|24497506 forkhead box A3 [Homo sapiens]
          Length = 350

 Score =  114 bits (285), Expect = 2e-25
 Identities = 80/243 (32%), Positives = 109/243 (44%), Gaps = 21/243 (8%)

Query: 16  PQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLI 75
           P   L  T   LG +   G   SS   +PG        + K         KP YSY +LI
Sbjct: 70  PAAPLGPTFPGLGVS---GGSSSSGYGAPGPGLVHGKEMPKGYRRPLAHAKPPYSYISLI 126

Query: 76  TYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPG 135
           T AI  +P K +TLSEIY+WI D FPYY+     W+NSIRH+LS N CF KV R  D PG
Sbjct: 127 TMAIQQAPGKMLTLSEIYQWIMDLFPYYRENQQRWQNSIRHSLSFNDCFVKVARSPDKPG 186

Query: 136 KGSYWTIDTCPD--------ISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPP 187
           KGSYW +             + R++R   ++ + +      A+ + R G   +   + P 
Sbjct: 187 KGSYWALHPSSGNMFENGCYLRRQKRFKLEEKVKKGG--SGAATTTRNGTGSAASTTTPA 244

Query: 188 ---EGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPL-----YNTNHDF 239
                 PQ    +P   A   +  G++D G+ A+        E P  L     YN NH F
Sbjct: 245 ATVTSPPQPPPPAPEPEAQGGEDVGALDCGSPASSTPYFTGLELPGELKLDAPYNFNHPF 304

Query: 240 KFS 242
             +
Sbjct: 305 SIN 307



 Score = 31.2 bits (69), Expect = 2.7
 Identities = 19/46 (41%), Positives = 22/46 (47%), Gaps = 9/46 (19%)

Query: 307 PPQPPPQQSQPQQQQAPAQGPSAVG----GAPPLHTPSTDGCTPPG 348
           PPQPPP   +P+     AQG   VG    G+P   TP   G   PG
Sbjct: 250 PPQPPPPAPEPE-----AQGGEDVGALDCGSPASSTPYFTGLELPG 290


>gi|24497504 forkhead box A2 isoform 2 [Homo sapiens]
          Length = 457

 Score =  111 bits (278), Expect = 2e-24
 Identities = 75/185 (40%), Positives = 96/185 (51%), Gaps = 25/185 (13%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY +LIT AI  SP K +TLSEIY+WI D FP+Y+     W+NSIRH+LS N CF 
Sbjct: 159 KPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFL 218

Query: 126 KVPRPRDDPGKGSYWTIDTCPD----------ISRKRRHPPDDDLSQDSPE------QEA 169
           KVPR  D PGKGS+WT+   PD          + R++R   +  L+           ++A
Sbjct: 219 KVPRSPDKPGKGSFWTLH--PDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKA 276

Query: 170 SKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQ-----GTGSVDGGAVAAGASGRE 224
           +   +   A  GEA+ P    P    +SP S AS  Q     G G +  G  AA  S  E
Sbjct: 277 AAGAQASQAQLGEAAGPASETP-AGTESPHSSASPCQEHKRGGLGELK-GTPAAALSPPE 334

Query: 225 SAEGP 229
            A  P
Sbjct: 335 PAPSP 339



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 25/111 (22%)

Query: 307 PPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPPVMAMH 366
           PP+P P   Q QQ  A   GP    G PP      +    P    A    +    +M+  
Sbjct: 332 PPEPAPSPGQQQQAAAHLLGPPHHPGLPP------EAHLKPEHHYAFNHPFSINNLMSSE 385

Query: 367 PPPLQHGGYHPHQHH-PHS-----------HPAQQPPPPQPQAQGQAPINN 405
               QH  +H H HH PH            +P    P P   A G  P+ N
Sbjct: 386 Q---QH--HHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMG--PVTN 429


>gi|194394143 forkhead box A2 isoform 1 [Homo sapiens]
          Length = 463

 Score =  111 bits (278), Expect = 2e-24
 Identities = 75/185 (40%), Positives = 96/185 (51%), Gaps = 25/185 (13%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY +LIT AI  SP K +TLSEIY+WI D FP+Y+     W+NSIRH+LS N CF 
Sbjct: 165 KPPYSYISLITMAIQQSPNKMLTLSEIYQWIMDLFPFYRQNQQRWQNSIRHSLSFNDCFL 224

Query: 126 KVPRPRDDPGKGSYWTIDTCPD----------ISRKRRHPPDDDLSQDSPE------QEA 169
           KVPR  D PGKGS+WT+   PD          + R++R   +  L+           ++A
Sbjct: 225 KVPRSPDKPGKGSFWTLH--PDSGNMFENGCYLRRQKRFKCEKQLALKEAAGAAGSGKKA 282

Query: 170 SKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQ-----GTGSVDGGAVAAGASGRE 224
           +   +   A  GEA+ P    P    +SP S AS  Q     G G +  G  AA  S  E
Sbjct: 283 AAGAQASQAQLGEAAGPASETP-AGTESPHSSASPCQEHKRGGLGELK-GTPAAALSPPE 340

Query: 225 SAEGP 229
            A  P
Sbjct: 341 PAPSP 345



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 31/111 (27%), Positives = 39/111 (35%), Gaps = 25/111 (22%)

Query: 307 PPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYGPPPVMAMH 366
           PP+P P   Q QQ  A   GP    G PP      +    P    A    +    +M+  
Sbjct: 338 PPEPAPSPGQQQQAAAHLLGPPHHPGLPP------EAHLKPEHHYAFNHPFSINNLMSSE 391

Query: 367 PPPLQHGGYHPHQHH-PHS-----------HPAQQPPPPQPQAQGQAPINN 405
               QH  +H H HH PH            +P    P P   A G  P+ N
Sbjct: 392 Q---QH--HHSHHHHQPHKMDLKAYEQVMHYPGYGSPMPGSLAMG--PVTN 435


>gi|24497501 forkhead box A1 [Homo sapiens]
          Length = 472

 Score =  110 bits (275), Expect = 4e-24
 Identities = 65/178 (36%), Positives = 92/178 (51%), Gaps = 27/178 (15%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY +LIT AI  +P+K +TLSEIY+WI D FPYY+     W+NSIRH+LS N CF 
Sbjct: 170 KPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSIRHSLSFNDCFV 229

Query: 126 KVPRPRDDPGKGSYWTIDTCPDISRKRRHPPDDDLSQD------SPEQEASKSP-RGGVA 178
           KV R  D PGKGSYWT+           HP   ++ ++          +  K P  GG  
Sbjct: 230 KVARSPDKPGKGSYWTL-----------HPDSGNMFENGCYLRRQKRFKCEKQPGAGGGG 278

Query: 179 GSGEASLPPEGNPQ-----MSLQSPTSIASYSQG----TGSVDGGAVAAGASGRESAE 227
           GSG      +G P+         +P++ +   +G    TG ++G      A+  ++ +
Sbjct: 279 GSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQTLD 336


>gi|4557595 forkhead box F2 [Homo sapiens]
          Length = 444

 Score =  110 bits (275), Expect = 4e-24
 Identities = 52/115 (45%), Positives = 72/115 (62%)

Query: 29  SASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMT 88
           S S + P  + +    G     +    K  + + +  KP YSY  LI  AI SSP+K++T
Sbjct: 63  SNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYIALIVMAIQSSPSKRLT 122

Query: 89  LSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTID 143
           LSEIY+++   FP+++ A  GWKNS+RHNLSLN+CF K+P+    PGKG YWTID
Sbjct: 123 LSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTID 177


>gi|32307177 forkhead box G1 [Homo sapiens]
          Length = 489

 Score =  109 bits (273), Expect = 6e-24
 Identities = 50/82 (60%), Positives = 59/82 (71%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP +SY  LI  AI  SP K++TL+ IY +I  NFPYY+    GW+NSIRHNLSLNKCF 
Sbjct: 181 KPPFSYNALIMMAIRQSPEKRLTLNGIYEFIMKNFPYYRENKQGWQNSIRHNLSLNKCFV 240

Query: 126 KVPRPRDDPGKGSYWTIDTCPD 147
           KVPR  DDPGKG+YW +D   D
Sbjct: 241 KVPRHYDDPGKGNYWMLDPSSD 262



 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 39/134 (29%), Positives = 58/134 (43%), Gaps = 14/134 (10%)

Query: 252 SWSFRNLYKSMLEKSSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQQ-----QQQQQ 306
           S+S  +L    ++  +  + HG  +     P  ++++ +    PPPP  Q     QQQQ 
Sbjct: 17  SFSINSLVPEAVQNDNHHASHGHHN--SHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQP 74

Query: 307 PPQPPPQQSQPQQQQAPA----QGPSAVGGAPPLHTP---STDGCTPPGGKQAGAEGYGP 359
           PP PPP    PQ + APA    +GP  +   PP   P   + DG    G    G  G GP
Sbjct: 75  PPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPPPPAAALDGAKADGLGGKGEPGGGP 134

Query: 360 PPVMAMHPPPLQHG 373
             +  + P   + G
Sbjct: 135 GELAPVGPDEKEKG 148



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 17/38 (44%), Positives = 18/38 (47%), Gaps = 7/38 (18%)

Query: 372 HGGYHPHQHHPHSH-------PAQQPPPPQPQAQGQAP 402
           H  +HP  HH H H       PA QPPPP  Q Q   P
Sbjct: 40  HNSHHPQHHHHHHHHHHHPPPPAPQPPPPPQQQQPPPP 77


>gi|110735445 forkhead box F1 [Homo sapiens]
          Length = 379

 Score =  109 bits (272), Expect = 8e-24
 Identities = 51/103 (49%), Positives = 69/103 (66%), Gaps = 4/103 (3%)

Query: 45  GSPTDPNAT----LSKDEAAVHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNF 100
           G+  DP ++      K  A + +  KP YSY  LI  AI SSP K++TLSEIY+++   F
Sbjct: 23  GAAMDPASSGPSKAKKTNAGIRRPEKPPYSYIALIVMAIQSSPTKRLTLSEIYQFLQSRF 82

Query: 101 PYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTID 143
           P+++ +  GWKNS+RHNLSLN+CF K+P+    PGKG YWTID
Sbjct: 83  PFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGHYWTID 125


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score =  109 bits (272), Expect = 8e-24
 Identities = 62/143 (43%), Positives = 78/143 (54%), Gaps = 5/143 (3%)

Query: 1   MASDLESSLTSIDWLPQLTLRATIEKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAA 60
           +A D E S    D  P+      +   G+A+ AG PG     + G+        S   A 
Sbjct: 67  LAEDEEESGGCSDGEPR-----ALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAAT 121

Query: 61  VHQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSL 120
                KP YSY  LIT AI  SP K++TLSEI  +I   FPYY+     W+NSIRHNLSL
Sbjct: 122 RSPLVKPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSL 181

Query: 121 NKCFRKVPRPRDDPGKGSYWTID 143
           N CF K+PR   +PGKG+YWT+D
Sbjct: 182 NDCFVKIPREPGNPGKGNYWTLD 204



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 69/302 (22%), Positives = 98/302 (32%), Gaps = 62/302 (20%)

Query: 147 DISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQ 206
           D+      PP ++   D  E E       G    GE           +  SP   A+ ++
Sbjct: 50  DVLPHGHEPPAEEAEADLAEDEEES----GGCSDGEPRALASRGAAAAAGSPGPGAAAAR 105

Query: 207 GTGSVDGGAVAAGASGRESAEGPPPLYNT--------NHDFKFSYSEINFQDLSWSFRNL 258
           G      G  + GA+ R     PP  Y          +   + + SEI  + +S  F   
Sbjct: 106 GAAGPGPGPPSGGAATRSPLVKPPYSYIALITMAILQSPKKRLTLSEI-CEFISGRFP-Y 163

Query: 259 YKSMLEKSSSSSQHGFSSLLGDI----------PPSNNYYMYQQQQPPP------PQQQQ 302
           Y+       +S +H  S  L D           P   NY+    +           ++++
Sbjct: 164 YREKFPAWQNSIRHNLS--LNDCFVKIPREPGNPGKGNYWTLDPESADMFDNGSFLRRRK 221

Query: 303 QQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYG---- 358
           + ++ P PPP        +   +G +A  G P        G   PG    GA GYG    
Sbjct: 222 RFKRQPLPPPHPHPHPHPELLLRGGAAAAGDP--------GAFLPGFAAYGAYGYGYGLA 273

Query: 359 ------PPPVMAMHPPPLQH-------GGYHPHQHHPHSHPAQQPPPPQPQAQ-----GQ 400
                 PPP  A HP P  H           P Q       A  PPP  P A      G 
Sbjct: 274 LPAYGAPPPGPAPHPHPHPHAFAFAAAAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGS 333

Query: 401 AP 402
           AP
Sbjct: 334 AP 335


>gi|6912372 forkhead box D3 [Homo sapiens]
          Length = 478

 Score =  107 bits (268), Expect = 2e-23
 Identities = 71/196 (36%), Positives = 92/196 (46%), Gaps = 35/196 (17%)

Query: 28  GSASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYATLITYAINSSPAKKM 87
           G AS  GP   S      +P+ P  +L K          P YSY  LIT AI  SP KK+
Sbjct: 113 GGASGGGPGAGSGSAGGLAPSKPKNSLVK----------PPYSYIALITMAILQSPQKKL 162

Query: 88  TLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDDPGKGSYWTIDTCPD 147
           TLS I  +I + FPYY+     W+NSIRHNLSLN CF K+PR   +PGKG+YWT+D    
Sbjct: 163 TLSGICEFISNRFPYYREKFPAWQNSIRHNLSLNDCFVKIPREPGNPGKGNYWTLD---- 218

Query: 148 ISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASLPPEGNPQMSLQSPTSIASYSQG 207
                  P  +D+  +       K  +               + Q  L+  T++   S G
Sbjct: 219 -------PQSEDMFDNGSFLRRRKRFK--------------RHQQEHLREQTALMMQSFG 257

Query: 208 TGSVDGGAVAAGASGR 223
             S+   A AAG  GR
Sbjct: 258 AYSLAAAAGAAGPYGR 273



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 26/71 (36%), Positives = 32/71 (45%), Gaps = 6/71 (8%)

Query: 295 PPPPQQQQQQQQPPQPPPQ-QSQPQQQQAPAQGPSAVG-GAPP---LHTPSTDGCT-PPG 348
           PP  +  +  + PP  P   Q QP  QQ       A G GA P   +  P  DGC    G
Sbjct: 50  PPELRLDEADEVPPAAPHHGQPQPPHQQPLTLPKEAAGAGAGPGGDVGAPEADGCKGGVG 109

Query: 349 GKQAGAEGYGP 359
           G++ GA G GP
Sbjct: 110 GEEGGASGGGP 120


>gi|12751477 forkhead box L2 [Homo sapiens]
          Length = 376

 Score =  106 bits (265), Expect = 5e-23
 Identities = 83/307 (27%), Positives = 120/307 (39%), Gaps = 58/307 (18%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY  LI  AI  S  K++TLS IY++I   FP+Y+    GW+NSIRHNLSLN+CF 
Sbjct: 54  KPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFI 113

Query: 126 KVPRPRDDPGKGSYWTID-TCPDISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEAS 184
           KVPR      KG+YWT+D  C D+  K  +     + +      A   P  G+ G+G A+
Sbjct: 114 KVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAA 173

Query: 185 ----------------------------------LPPEGNPQMSLQ-----SPTSIASYS 205
                                              PP   P  S Q     +  + A+ +
Sbjct: 174 GGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAA 233

Query: 206 QGTGSVDGGAVAAGASGRESAEGPPPLYNTNHDFKFSYSEINFQDLSWSFRNLYKSMLEK 265
            G GS    AV  G +G  ++ GP             Y+ +    L     N Y  +   
Sbjct: 234 AGPGSPGAAAVVKGLAGPAASYGP-------------YTRVQSMALPPGVVNSYNGLGGP 280

Query: 266 SSSSSQHGFSSLLGDIPPSNNYYMYQQQQPPPPQQQQQQQQPPQPPPQQSQPQQQQAPAQ 325
            ++             P  + ++++    PPP         PP      + P     PA 
Sbjct: 281 PAAPPPPPHPH-----PHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAP 335

Query: 326 GPSAVGG 332
            P++  G
Sbjct: 336 APTSAPG 342



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 36/116 (31%), Positives = 41/116 (35%), Gaps = 23/116 (19%)

Query: 306 QPPQPPPQQS-------QPQQQQAPAQGPSAVGGAPPL------------HTPSTDGCTP 346
           QPP P P  S             A A GP + G A  +            +T       P
Sbjct: 208 QPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALP 267

Query: 347 PGGKQAGAEGYGPPPVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQAP 402
           PG   +   G G PP     PPP  H   HPH HH H+  A  P PP   A    P
Sbjct: 268 PGVVNS-YNGLGGPPAA---PPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPP 319



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 31/102 (30%), Positives = 44/102 (43%), Gaps = 26/102 (25%)

Query: 299 QQQQQQQQPPQPPPQQSQPQQQQAPAQGPSAVGGAPPLHTPSTDGCTPPGGKQAGAEGYG 358
           +++++ ++P +PPP   Q      P +G    GGA         GC   G   AGA+GYG
Sbjct: 144 RRRRRMKRPFRPPPAHFQ------PGKGLFGAGGA-------AGGCGVAG---AGADGYG 187

Query: 359 PPPVMAMHPPPLQHGGYHPHQHHPHSHPAQQPPPPQPQAQGQ 400
                 + PP     G+       +S P  QPP P P A  Q
Sbjct: 188 -----YLAPPKYLQSGF-----LNNSWPLPQPPSPMPYASCQ 219


>gi|31563338 forkhead box K2 [Homo sapiens]
          Length = 660

 Score =  106 bits (264), Expect = 7e-23
 Identities = 52/96 (54%), Positives = 65/96 (67%), Gaps = 6/96 (6%)

Query: 64  DGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKC 123
           D KP YSYA LI  AI  +P K++TL+ IY  I  N+PYY+ A  GW+NSIRHNLSLN+ 
Sbjct: 256 DSKPPYSYAQLIVQAITMAPDKQLTLNGIYTHITKNYPYYRTADKGWQNSIRHNLSLNRY 315

Query: 124 FRKVPRPRDDPGKGSYWTIDTCPDIS------RKRR 153
           F KVPR +++PGKGS+W ID   +        RKRR
Sbjct: 316 FIKVPRSQEEPGKGSFWRIDPASESKLIEQAFRKRR 351


>gi|21618325 forkhead box E1 [Homo sapiens]
          Length = 373

 Score =  105 bits (261), Expect = 1e-22
 Identities = 72/228 (31%), Positives = 108/228 (47%), Gaps = 35/228 (15%)

Query: 16  PQLTLRATI--EKLGSASQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQDGKPRYSYAT 73
           PQ  + AT+  E+  +A+ AG PG +     G          +      Q GKP YSY  
Sbjct: 10  PQPEVLATVKEERGETAAGAGVPGEATGRGAGG---------RRRKRPLQRGKPPYSYIA 60

Query: 74  LITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFRKVPRPRDD 133
           LI  AI  +P +++TL  IY++I + FP+Y++    W+NSIRHNL+LN CF K+PR    
Sbjct: 61  LIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGR 120

Query: 134 PGKGSYWTIDTCPD--------ISRKRRHPPDDDLSQDSPEQEASKSPRGGVAGSGEASL 185
           PGKG+YW +D   +        + R++R    D  +  +   +A+ +     A +  A++
Sbjct: 121 PGKGNYWALDPNAEDMFESGSFLRRRKRFKRSDLSTYPAYMHDAAAAAAAAAAAAAAAAI 180

Query: 186 PPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGPPPLY 233
            P   P      P               GAV AG +   S   PPP+Y
Sbjct: 181 FPGAVPAARPPYP---------------GAVYAGYA-PPSLAAPPPVY 212


>gi|82546824 forkhead box K1 [Homo sapiens]
          Length = 733

 Score =  104 bits (260), Expect = 2e-22
 Identities = 61/145 (42%), Positives = 81/145 (55%), Gaps = 18/145 (12%)

Query: 64  DGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKC 123
           + KP +SYA LI  AI+S+  +++TLS IY  I  ++PYY+ A  GW+NSIRHNLSLN+ 
Sbjct: 303 ESKPPFSYAQLIVQAISSAQDRQLTLSGIYAHITKHYPYYRTADKGWQNSIRHNLSLNRY 362

Query: 124 FRKVPRPRDDPGKGSYWTIDTCPDIS------RKRRH-----------PPDDDLSQDSPE 166
           F KVPR +++PGKGS+W ID   +        RKRR            P     +  SP 
Sbjct: 363 FIKVPRSQEEPGKGSFWRIDPASEAKLVEQAFRKRRQRGVSCFRTPFGPLSSRSAPASPT 422

Query: 167 QEASKSPRGGVAGSGEASLPPEGNP 191
                SPR G   + E  L  EG+P
Sbjct: 423 HPGLMSPRSGGLQTPEC-LSREGSP 446



 Score = 30.8 bits (68), Expect = 3.5
 Identities = 18/49 (36%), Positives = 19/49 (38%), Gaps = 8/49 (16%)

Query: 295 PPPPQQQQQQQQPPQPPPQQSQP--------QQQQAPAQGPSAVGGAPP 335
           PP P Q Q    PP PPP    P            +   G SAV GA P
Sbjct: 40  PPAPAQPQPPPGPPPPPPPPLPPGAIAGAGSSGGSSGVSGDSAVAGAAP 88


>gi|28973785 forkhead box S1 [Homo sapiens]
          Length = 330

 Score =  104 bits (259), Expect = 3e-22
 Identities = 62/140 (44%), Positives = 79/140 (56%), Gaps = 17/140 (12%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY  LI  AI SSP ++ TLS IYR+I   F +Y++   GW+NSIRHNLSLN+CF 
Sbjct: 18  KPPYSYIALIAMAIQSSPGQRATLSGIYRYIMGRFAFYRHNRPGWQNSIRHNLSLNECFV 77

Query: 126 KVPRPRDDPGKGSYWTID-TCPD-------ISRKRRHPPDDDL--------SQDSPEQEA 169
           KVPR    PGKGSYWT+D  C D       + R+RR               ++  P +  
Sbjct: 78  KVPRDDRKPGKGSYWTLDPDCHDMFEHGSFLRRRRRFTRQTGAEGTRGPAKARRGPLRAT 137

Query: 170 SKSPRGGVAGSG-EASLPPE 188
           S+ P    A +G + S PPE
Sbjct: 138 SQDPGVPNATTGRQCSFPPE 157


>gi|146232000 checkpoint suppressor 1 isoform 1 [Homo sapiens]
          Length = 490

 Score =  103 bits (256), Expect = 6e-22
 Identities = 55/141 (39%), Positives = 81/141 (57%), Gaps = 8/141 (5%)

Query: 6   ESSLTSIDWLPQLTLRATIEKLGSA--SQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQ 63
           +  LT+++WL +   +  ++  G +      P       +P SP   +      +A  + 
Sbjct: 57  DEELTNLNWLHES--KNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPY---DARQNP 111

Query: 64  DGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKC 123
           + KP YS++ LI  AI  SP K++ + +IY WI ++FPY+ NA  GWKNS+RHNLSLNKC
Sbjct: 112 NCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKC 171

Query: 124 FRKVPRPRDDP-GKGSYWTID 143
           F+KV + R    GKGS W ID
Sbjct: 172 FKKVDKERSQSIGKGSLWCID 192


>gi|51093865 checkpoint suppressor 1 isoform 2 [Homo sapiens]
          Length = 468

 Score =  103 bits (256), Expect = 6e-22
 Identities = 55/141 (39%), Positives = 81/141 (57%), Gaps = 8/141 (5%)

Query: 6   ESSLTSIDWLPQLTLRATIEKLGSA--SQAGPPGSSRKCSPGSPTDPNATLSKDEAAVHQ 63
           +  LT+++WL +   +  ++  G +      P       +P SP   +      +A  + 
Sbjct: 57  DEELTNLNWLHES--KNLLKSFGESVLRSVSPVQDLDDDTPPSPAHSDMPY---DARQNP 111

Query: 64  DGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKC 123
           + KP YS++ LI  AI  SP K++ + +IY WI ++FPY+ NA  GWKNS+RHNLSLNKC
Sbjct: 112 NCKPPYSFSCLIFMAIEDSPTKRLPVKDIYNWILEHFPYFANAPTGWKNSVRHNLSLNKC 171

Query: 124 FRKVPRPRDDP-GKGSYWTID 143
           F+KV + R    GKGS W ID
Sbjct: 172 FKKVDKERSQSIGKGSLWCID 192


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score =  102 bits (255), Expect = 7e-22
 Identities = 47/78 (60%), Positives = 56/78 (71%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           KP YSY  LIT AI  SP K++TLSEI  +I   FPYY+     W+NSIRHNLSLN CF 
Sbjct: 125 KPPYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFV 184

Query: 126 KVPRPRDDPGKGSYWTID 143
           K+PR   +PGKG+YWT+D
Sbjct: 185 KIPREPGNPGKGNYWTLD 202


>gi|105554437 forkhead box B1 [Homo sapiens]
          Length = 325

 Score =  102 bits (255), Expect = 7e-22
 Identities = 47/88 (53%), Positives = 60/88 (68%), Gaps = 1/88 (1%)

Query: 62  HQDGKPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLN 121
           + D KP YSY +L   AI SSP K + LSEIY++I D FPYY+     W+NS+RHNLS N
Sbjct: 9   YSDQKPPYSYISLTAMAIQSSPEKMLPLSEIYKFIMDRFPYYRENTQRWQNSLRHNLSFN 68

Query: 122 KCFRKVPRPRDDPGKGSYWTI-DTCPDI 148
            CF K+PR  D PGKGS+W +  +C D+
Sbjct: 69  DCFIKIPRRPDQPGKGSFWALHPSCGDM 96


>gi|169171269 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 632

 Score =  102 bits (254), Expect = 1e-21
 Identities = 70/192 (36%), Positives = 89/192 (46%), Gaps = 35/192 (18%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           +P YSY  LI  AI  SPA ++TLS IY +I   FPYY+     W+NSIRHNLSLN CF 
Sbjct: 32  RPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFV 91

Query: 126 KVPRPR-DDPGKGSYWTI-DTCPDI--------SRKRRHPPDDDLSQDSPEQEASKSPRG 175
           KVPR    + GKG+YWT   +C  +         R+RR        +  P++E  + PR 
Sbjct: 92  KVPRSEGHEKGKGNYWTFAGSCESLLDLFENGNYRRRRR-------RRGPKREGPRGPRA 144

Query: 176 GVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGP-PPLYN 234
           G A                 Q P+  +      G +   +   GA GRE    P PP   
Sbjct: 145 GGA-----------------QGPSGPSELPAAQGRLAPDSAGEGAPGREPPASPAPPGKE 187

Query: 235 TNHDFKFSYSEI 246
              D KFS   I
Sbjct: 188 HPRDLKFSIDYI 199


>gi|169172132 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 528

 Score =  102 bits (254), Expect = 1e-21
 Identities = 71/192 (36%), Positives = 90/192 (46%), Gaps = 35/192 (18%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           +P YSY  LI  AI  SPA ++TLS IY +I   FPYY+     W+NSIRHNLSLN CF 
Sbjct: 327 RPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFV 386

Query: 126 KVPRPR-DDPGKGSYWT--------IDTCPDISRKRRHPPDDDLSQDSPEQEASKSPR-G 175
           KVPR    + GKG+YWT        +D   + + +RR        +  P++E  + PR G
Sbjct: 387 KVPRSEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRR------RRRGPKREGPRGPRAG 440

Query: 176 GVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGP-PPLYN 234
           G  G    S PP    +++  S                     GA GRE    P PP   
Sbjct: 441 GAQGPSGPSEPPAAQGRLAPDS------------------AGEGAPGREPPASPAPPGKE 482

Query: 235 TNHDFKFSYSEI 246
              D KFS   I
Sbjct: 483 HPRDLKFSIDYI 494


>gi|113419423 PREDICTED: similar to forkhead box L2 [Homo sapiens]
          Length = 387

 Score =  102 bits (254), Expect = 1e-21
 Identities = 71/192 (36%), Positives = 90/192 (46%), Gaps = 35/192 (18%)

Query: 66  KPRYSYATLITYAINSSPAKKMTLSEIYRWICDNFPYYKNAGIGWKNSIRHNLSLNKCFR 125
           +P YSY  LI  AI  SPA ++TLS IY +I   FPYY+     W+NSIRHNLSLN CF 
Sbjct: 94  RPAYSYIALIAMAIQQSPAGRVTLSGIYDFIMRKFPYYRANQRAWQNSIRHNLSLNSCFV 153

Query: 126 KVPRPR-DDPGKGSYWT--------IDTCPDISRKRRHPPDDDLSQDSPEQEASKSPR-G 175
           KVPR    + GKG+YWT        +D   + + +RR        +  P++E  + PR G
Sbjct: 154 KVPRSEGHEKGKGNYWTFAGGCESLLDLFENGNYRRRR------RRRGPKREGPRGPRAG 207

Query: 176 GVAGSGEASLPPEGNPQMSLQSPTSIASYSQGTGSVDGGAVAAGASGRESAEGP-PPLYN 234
           G  G    S PP    +++  S                     GA GRE    P PP   
Sbjct: 208 GAQGPSGPSEPPAAQGRLAPDS------------------AGEGAPGREPPASPAPPGKE 249

Query: 235 TNHDFKFSYSEI 246
              D KFS   I
Sbjct: 250 HPRDLKFSIDYI 261


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.129    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,329,911
Number of Sequences: 37866
Number of extensions: 2260338
Number of successful extensions: 33257
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 577
Number of HSP's successfully gapped in prelim test: 1032
Number of HSP's that attempted gapping in prelim test: 13679
Number of HSP's gapped (non-prelim): 10845
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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