Guide to the Human Genome
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Search of human proteins with 14149764

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|14149764 potassium channel, subfamily K, member 16 isoform 2
[Homo sapiens]
         (309 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|14149764 potassium channel, subfamily K, member 16 isoform 2 ...   633   0.0  
gi|205360983 potassium channel, subfamily K, member 16 isoform 3...   556   e-158
gi|205360973 potassium channel, subfamily K, member 16 isoform 4...   513   e-146
gi|205360971 potassium channel, subfamily K, member 16 isoform 1...   454   e-128
gi|17025230 potassium channel, subfamily K, member 17 isoform 1 ...   228   5e-60
gi|20143946 potassium channel, subfamily K, member 10 isoform 3 ...   199   3e-51
gi|20143944 potassium channel, subfamily K, member 10 isoform 2 ...   199   3e-51
gi|10863961 potassium channel, subfamily K, member 10 isoform 1 ...   199   3e-51
gi|14589851 potassium channel, subfamily K, member 2 isoform b [...   194   8e-50
gi|126365795 potassium channel, subfamily K, member 2 isoform c ...   194   8e-50
gi|62912487 potassium channel, subfamily K, member 2 isoform a [...   194   8e-50
gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]    194   8e-50
gi|205361107 potassium channel, subfamily K, member 17 isoform 2...   192   4e-49
gi|15718767 TRAAK [Homo sapiens]                                      185   5e-47
gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]    155   3e-38
gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]    154   1e-37
gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]    135   4e-32
gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]    131   9e-31
gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]   129   3e-30
gi|16118231 potassium channel, subfamily K, member 7 isoform A [...   112   5e-25
gi|11545761 potassium channel, subfamily K, member 12 [Homo sapi...   111   7e-25
gi|16306555 potassium channel, subfamily K, member 13 [Homo sapi...   110   2e-24
gi|16118235 potassium channel, subfamily K, member 7 isoform B [...   108   6e-24
gi|16118233 potassium channel, subfamily K, member 7 isoform B [...   108   6e-24
gi|5031821 potassium channel, subfamily K, member 7 isoform C [H...   107   1e-23
gi|32469495 potassium channel, subfamily K, member 18 [Homo sapi...    63   3e-10
gi|4504831 potassium voltage-gated channel, subfamily H, member ...    42   0.001
gi|27437001 potassium voltage-gated channel, subfamily H, member...    42   0.001
gi|22024390 potassium voltage-gated channel, subfamily H, member...    40   0.002
gi|27886648 potassium voltage-gated channel, subfamily H, member...    40   0.002

>gi|14149764 potassium channel, subfamily K, member 16 isoform 2
           [Homo sapiens]
          Length = 309

 Score =  633 bits (1633), Expect = 0.0
 Identities = 309/309 (100%), Positives = 309/309 (100%)

Query: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
           MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60

Query: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
           LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120

Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
           GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180

Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
           LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240

Query: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF 300
           LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF
Sbjct: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF 300

Query: 301 PISKKGLGS 309
           PISKKGLGS
Sbjct: 301 PISKKGLGS 309


>gi|205360983 potassium channel, subfamily K, member 16 isoform 3
           [Homo sapiens]
          Length = 294

 Score =  556 bits (1432), Expect = e-158
 Identities = 279/305 (91%), Positives = 280/305 (91%), Gaps = 14/305 (4%)

Query: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
           MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60

Query: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
           LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120

Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
           GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180

Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
           LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240

Query: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGC--GAKAAPGRRPRRGSTAARGVQVTPQ 298
           LLGLAWLALILPLGPLLLHRCCQLWLLS   G   GA + P   PR            PQ
Sbjct: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSRGLGVKDGAASDPSGLPR------------PQ 288

Query: 299 DFPIS 303
             PIS
Sbjct: 289 KIPIS 293


>gi|205360973 potassium channel, subfamily K, member 16 isoform 4
           [Homo sapiens]
          Length = 262

 Score =  513 bits (1322), Expect = e-146
 Identities = 262/309 (84%), Positives = 262/309 (84%), Gaps = 47/309 (15%)

Query: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
           MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60

Query: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
           LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120

Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
           GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180

Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWI 240
           LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG                   
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG------------------- 221

Query: 241 LLGLAWLALILPLGPLLLHRCCQLWLLSLRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF 300
                                       LRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF
Sbjct: 222 ----------------------------LRQGCGAKAAPGRRPRRGSTAARGVQVTPQDF 253

Query: 301 PISKKGLGS 309
           PISKKGLGS
Sbjct: 254 PISKKGLGS 262


>gi|205360971 potassium channel, subfamily K, member 16 isoform 1
           [Homo sapiens]
          Length = 322

 Score =  454 bits (1167), Expect = e-128
 Identities = 221/221 (100%), Positives = 221/221 (100%)

Query: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60
           MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC
Sbjct: 1   MPSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTC 60

Query: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120
           LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA
Sbjct: 61  LDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEA 120

Query: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180
           GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT
Sbjct: 121 GQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGT 180

Query: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221
           LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG
Sbjct: 181 LVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVG 221



 Score = 30.4 bits (67), Expect = 2.1
 Identities = 12/39 (30%), Positives = 20/39 (51%)

Query: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSL 235
           W F   F+FA   ++TIG+G+    T+  + +   Y  L
Sbjct: 93  WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131


>gi|17025230 potassium channel, subfamily K, member 17 isoform 1
           [Homo sapiens]
          Length = 332

 Score =  228 bits (581), Expect = 5e-60
 Identities = 112/259 (43%), Positives = 169/259 (65%), Gaps = 13/259 (5%)

Query: 2   PSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL 61
           P   +  C     + LLLAY+ YL LG  +F  LE +A   S   FQ +K   L+N+TCL
Sbjct: 10  PEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCL 69

Query: 62  DQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAG 121
           D+ A++  ++ +++A+  G +   N+T+   W+   SFFF+ + +TTIGYGNL+P+T A 
Sbjct: 70  DRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAA 129

Query: 122 QVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDR-------PRRSQVLQVLGLAL 174
           ++FC+F+AL+GIPLN++ LN LG  ++     +  W  R       P +++ L   G   
Sbjct: 130 RLFCIFFALVGIPLNLVVLNRLGHLMQ---QGVNHWASRLGGTWQDPDKARWLAGSGA-- 184

Query: 175 FLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRS 234
            L  G L+ L+ PP++FSH+EGWS++EGFYFAFITLST+GFGDYV+G +PS+ Y   Y++
Sbjct: 185 -LLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIGMNPSQRYPLWYKN 243

Query: 235 LAAIWILLGLAWLALILPL 253
           + ++WIL G+AWLALI+ L
Sbjct: 244 MVSLWILFGMAWLALIIKL 262


>gi|20143946 potassium channel, subfamily K, member 10 isoform 3
           [Homo sapiens]
          Length = 543

 Score =  199 bits (506), Expect = 3e-51
 Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V+ + +  V YL+ G  +F+ LE+  E+  ++   LEK  FL ++ C+    +E  +Q  
Sbjct: 77  VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 136

Query: 74  MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           ++A   GV+P GNS+N  S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 137 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 196

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E+   + + SQ  ++V+   LF+  G +V +  P
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F ++EGW+  E  YF  +TL+T+GFGD+V G +   +Y   Y+ L   WIL+GLA+ 
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 316

Query: 248 ALILPL 253
           A +L +
Sbjct: 317 AAVLSM 322


>gi|20143944 potassium channel, subfamily K, member 10 isoform 2
           [Homo sapiens]
          Length = 543

 Score =  199 bits (506), Expect = 3e-51
 Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V+ + +  V YL+ G  +F+ LE+  E+  ++   LEK  FL ++ C+    +E  +Q  
Sbjct: 77  VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 136

Query: 74  MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           ++A   GV+P GNS+N  S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 137 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 196

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E+   + + SQ  ++V+   LF+  G +V +  P
Sbjct: 197 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 256

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F ++EGW+  E  YF  +TL+T+GFGD+V G +   +Y   Y+ L   WIL+GLA+ 
Sbjct: 257 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 316

Query: 248 ALILPL 253
           A +L +
Sbjct: 317 AAVLSM 322


>gi|10863961 potassium channel, subfamily K, member 10 isoform 1
           [Homo sapiens]
          Length = 538

 Score =  199 bits (506), Expect = 3e-51
 Identities = 99/246 (40%), Positives = 154/246 (62%), Gaps = 6/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V+ + +  V YL+ G  +F+ LE+  E+  ++   LEK  FL ++ C+    +E  +Q  
Sbjct: 72  VVAIFVVVVVYLVTGGLVFRALEQPFESSQKNTIALEKAEFLRDHVCVSPQELETLIQHA 131

Query: 74  MEAWVKGVNPKGNSTN-PSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           ++A   GV+P GNS+N  S+WD GS+FFFAGTV+TTIGYGN+APSTE G++FC+ YA+ G
Sbjct: 132 LDADNAGVSPIGNSSNNSSHWDLGSAFFFAGTVITTIGYGNIAPSTEGGKIFCILYAIFG 191

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E+   + + SQ  ++V+   LF+  G +V +  P
Sbjct: 192 IPLFGFLLAGIGDQLGTIFGKSIARVEKVFRKKQVSQTKIRVISTILFILAGCIVFVTIP 251

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F ++EGW+  E  YF  +TL+T+GFGD+V G +   +Y   Y+ L   WIL+GLA+ 
Sbjct: 252 AVIFKYIEGWTALESIYFVVVTLTTVGFGDFVAGGNAGINYREWYKPLVWFWILVGLAYF 311

Query: 248 ALILPL 253
           A +L +
Sbjct: 312 AAVLSM 317


>gi|14589851 potassium channel, subfamily K, member 2 isoform b
           [Homo sapiens]
          Length = 411

 Score =  194 bits (493), Expect = 8e-50
 Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V  + L  V YL++GAT+F+ LE+  E   R    ++K  F+  ++C++   +++ +Q I
Sbjct: 47  VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 106

Query: 74  MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           + A   G+ P GN++N  S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 107 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 166

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E    +   SQ  ++++   +F+  G ++ +  P
Sbjct: 167 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 226

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F H+EGWS  +  YF  ITL+TIGFGDYV G    + Y+  Y+ +   WIL+GLA+ 
Sbjct: 227 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 285

Query: 248 ALILPL 253
           A +L +
Sbjct: 286 AAVLSM 291


>gi|126365795 potassium channel, subfamily K, member 2 isoform c
           [Homo sapiens]
          Length = 426

 Score =  194 bits (493), Expect = 8e-50
 Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V  + L  V YL++GAT+F+ LE+  E   R    ++K  F+  ++C++   +++ +Q I
Sbjct: 62  VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 121

Query: 74  MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           + A   G+ P GN++N  S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 122 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 181

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E    +   SQ  ++++   +F+  G ++ +  P
Sbjct: 182 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 241

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F H+EGWS  +  YF  ITL+TIGFGDYV G    + Y+  Y+ +   WIL+GLA+ 
Sbjct: 242 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 300

Query: 248 ALILPL 253
           A +L +
Sbjct: 301 AAVLSM 306


>gi|62912487 potassium channel, subfamily K, member 2 isoform a
           [Homo sapiens]
          Length = 422

 Score =  194 bits (493), Expect = 8e-50
 Identities = 98/246 (39%), Positives = 153/246 (62%), Gaps = 7/246 (2%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           V  + L  V YL++GAT+F+ LE+  E   R    ++K  F+  ++C++   +++ +Q I
Sbjct: 58  VSTIFLVVVLYLIIGATVFKALEQPHEISQRTTIVIQKQTFISQHSCVNSTELDELIQQI 117

Query: 74  MEAWVKGVNPKGNSTNP-SNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           + A   G+ P GN++N  S+WD GSSFFFAGTV+TTIG+GN++P TE G++FC+ YALLG
Sbjct: 118 VAAINAGIIPLGNTSNQISHWDLGSSFFFAGTVITTIGFGNISPRTEGGKIFCIIYALLG 177

Query: 133 IPLNVIFL----NHLGTGLRAHLAAIERWEDRPRRSQV-LQVLGLALFLTLGTLVILIFP 187
           IPL    L    + LGT     +A +E    +   SQ  ++++   +F+  G ++ +  P
Sbjct: 178 IPLFGFLLAGVGDQLGTIFGKGIAKVEDTFIKWNVSQTKIRIISTIIFILFGCVLFVALP 237

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
            ++F H+EGWS  +  YF  ITL+TIGFGDYV G    + Y+  Y+ +   WIL+GLA+ 
Sbjct: 238 AIIFKHIEGWSALDAIYFVVITLTTIGFGDYVAGGSDIE-YLDFYKPVVWFWILVGLAYF 296

Query: 248 ALILPL 253
           A +L +
Sbjct: 297 AAVLSM 302


>gi|4504851 potassium channel, subfamily K, member 5 [Homo sapiens]
          Length = 499

 Score =  194 bits (493), Expect = 8e-50
 Identities = 97/238 (40%), Positives = 152/238 (63%), Gaps = 3/238 (1%)

Query: 16  PLLL-AYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIM 74
           PLL  A + YL +GA IF++LE     +++  +  +KL  L+ + CL Q  +++ ++V+ 
Sbjct: 6   PLLTSAIIFYLAIGAAIFEVLEEPHWKEAKKNYYTQKLHLLKEFPCLGQEGLDKILEVVS 65

Query: 75  EAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
           +A  +GV   GN T  +NW++ ++  FA TV+TTIGYGN+AP T AG++FCVFY L G+P
Sbjct: 66  DAAGQGVAITGNQTF-NNWNWPNAMIFAATVITTIGYGNVAPKTPAGRLFCVFYGLFGVP 124

Query: 135 LNVIFLNHLGTGLRAHLAAIERWEDRPRRS-QVLQVLGLALFLTLGTLVILIFPPMVFSH 193
           L + +++ LG         + ++  +   S +  Q+    +F+  G LV L+ PP VF  
Sbjct: 125 LCLTWISALGKFFGGRAKRLGQFLTKRGVSLRKAQITCTVIFIVWGVLVHLVIPPFVFMV 184

Query: 194 VEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
            EGW++ EG Y++FIT+STIGFGD+V G +PS +Y ++YR    +WI LGLAWL+L +
Sbjct: 185 TEGWNYIEGLYYSFITISTIGFGDFVAGVNPSANYHALYRYFVELWIYLGLAWLSLFV 242


>gi|205361107 potassium channel, subfamily K, member 17 isoform 2
           [Homo sapiens]
          Length = 271

 Score =  192 bits (487), Expect = 4e-49
 Identities = 96/228 (42%), Positives = 145/228 (63%), Gaps = 13/228 (5%)

Query: 2   PSAGLCSCWGGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL 61
           P   +  C     + LLLAY+ YL LG  +F  LE +A   S   FQ +K   L+N+TCL
Sbjct: 10  PEGRVRGCAVPSTVLLLLAYLAYLALGTGVFWTLEGRAAQDSSRSFQRDKWELLQNFTCL 69

Query: 62  DQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAG 121
           D+ A++  ++ +++A+  G +   N+T+   W+   SFFF+ + +TTIGYGNL+P+T A 
Sbjct: 70  DRPALDSLIRDVVQAYKNGASLLSNTTSMGRWELVGSFFFSVSTITTIGYGNLSPNTMAA 129

Query: 122 QVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERWEDR-------PRRSQVLQVLGLAL 174
           ++FC+F+AL+GIPLN++ LN LG  ++     +  W  R       P +++ L   G   
Sbjct: 130 RLFCIFFALVGIPLNLVVLNRLGHLMQ---QGVNHWASRLGGTWQDPDKARWLAGSGA-- 184

Query: 175 FLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGT 222
            L  G L+ L+ PP++FSH+EGWS++EGFYFAFITLST+GFGDYV+ +
Sbjct: 185 -LLSGLLLFLLLPPLLFSHMEGWSYTEGFYFAFITLSTVGFGDYVIAS 231


>gi|15718767 TRAAK [Homo sapiens]
          Length = 393

 Score =  185 bits (469), Expect = 5e-47
 Identities = 101/249 (40%), Positives = 154/249 (61%), Gaps = 15/249 (6%)

Query: 14  VLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVI 73
           +L LL   + YL+ GA +F+ LE+  E Q++ +    + +FL  + C+    +   ++ +
Sbjct: 6   LLALLALVLLYLVSGALVFRALEQPHEQQAQRELGEVREKFLRAHPCVSDQELGLLIKEV 65

Query: 74  MEAWVKGVNPKGNSTNPSN---WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYAL 130
            +A   G +P+ NST+ S+   WD GS+FFF+GT++TTIGYGN+A  T+AG++FC+FYAL
Sbjct: 66  ADALGGGADPETNSTSNSSHSAWDLGSAFFFSGTIITTIGYGNVALRTDAGRLFCIFYAL 125

Query: 131 LGIPLNVIFL----NHLGTGLRAHLAAIE----RWEDRPRRSQVLQVLGLALFLTLGTLV 182
           +GIPL  I L    + LG+ LR  +  IE    +W   P   ++++VL   LFL +G L+
Sbjct: 126 VGIPLFGILLAGVGDRLGSSLRHGIGHIEAIFLKWHVPP---ELVRVLSAMLFLLIGCLL 182

Query: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILL 242
            ++ P  VF ++E WS  E  YF  +TL+T+GFGDYV G DP +     Y+ L   WILL
Sbjct: 183 FVLTPTFVFCYMEDWSKLEAIYFVIVTLTTVGFGDYVAGADP-RQDSPAYQPLVWFWILL 241

Query: 243 GLAWLALIL 251
           GLA+ A +L
Sbjct: 242 GLAYFASVL 250


>gi|4504847 potassium channel, subfamily K, member 1 [Homo sapiens]
          Length = 336

 Score =  155 bits (393), Expect = 3e-38
 Identities = 86/239 (35%), Positives = 136/239 (56%), Gaps = 4/239 (1%)

Query: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQVIMEA 76
           L+L Y+ YL+ GA +F  +E   E   R + +  K RFLE + CL +  +EQF+  ++EA
Sbjct: 26  LVLGYLLYLVFGAVVFSSVELPYEDLLRQELRKLKRRFLEEHECLSEQQLEQFLGRVLEA 85

Query: 77  WVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLN 136
              GV+   N++   NWDF S+ FFA TV++T GYG+  P ++ G+ FC+ Y+++GIP  
Sbjct: 86  SNYGVSVLSNASGNWNWDFTSALFFASTVLSTTGYGHTVPLSDGGKAFCIIYSVIGIPFT 145

Query: 137 VIFLNHLGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF---PPMVFSH 193
           ++FL  +   +  H+          R     QV+ +   + LG + +  F   P  VFS 
Sbjct: 146 LLFLTAVVQRITVHVTRRPVLYFHIRWGFSKQVVAIVHAVLLGFVTVSCFFFIPAAVFSV 205

Query: 194 VE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALIL 251
           +E  W+F E FYF FI+LSTIG GDYV G   ++ +  +Y+     ++LLGL  + ++L
Sbjct: 206 LEDDWNFLESFYFCFISLSTIGLGDYVPGEGYNQKFRELYKIGITCYLLLGLIAMLVVL 264


>gi|4758624 potassium channel, subfamily K, member 6 [Homo sapiens]
          Length = 313

 Score =  154 bits (389), Expect = 1e-37
 Identities = 90/255 (35%), Positives = 140/255 (54%), Gaps = 19/255 (7%)

Query: 11  GGRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFV 70
           G  +   L AY  YL+LGA +   LE   EA+ R + +  + + L+   C+   A++ FV
Sbjct: 4   GALLAGALAAYAAYLVLGALLVARLEGPHEARLRAELETLRAQLLQRSPCVAAPALDAFV 63

Query: 71  QVIMEAWVKGVNPKGNSTNPSN-----WDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
           + ++ A   G     N++  +N     WDF S+ FFA T++TT+GYG   P T+AG+ F 
Sbjct: 64  ERVLAAGRLGRVVLANASGSANASDPAWDFASALFFASTLITTVGYGYTTPLTDAGKAFS 123

Query: 126 VFYALLGIPLNVIFLNHLGTGLRAHLAAIE------RWEDRPRRSQVLQVLGLALFLTLG 179
           + +ALLG+P  ++ L      L   L  +       RW   PRR+    ++ L     LG
Sbjct: 124 IAFALLGVPTTMLLLTASAQRLSLLLTHVPLSWLSMRWGWDPRRAACWHLVAL-----LG 178

Query: 180 TLVILIF--PPMVFSHVE-GWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLA 236
            +V + F  P ++F+H+E  WSF + FYF FI+LSTIG GDYV G  P + Y ++Y+ L 
Sbjct: 179 VVVTVCFLVPAVIFAHLEEAWSFLDAFYFCFISLSTIGLGDYVPGEAPGQPYRALYKVLV 238

Query: 237 AIWILLGLAWLALIL 251
            +++ LGL  + L+L
Sbjct: 239 TVYLFLGLVAMVLVL 253



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 4/82 (4%)

Query: 197 WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPL 256
           W F+   +FA   ++T+G+G     TD  K +   +  L     +L L   A  L L  L
Sbjct: 91  WDFASALFFASTLITTVGYGYTTPLTDAGKAFSIAFALLGVPTTMLLLTASAQRLSL--L 148

Query: 257 LLHRCCQLWLLSLRQGCGAKAA 278
           L H    L  LS+R G   + A
Sbjct: 149 LTH--VPLSWLSMRWGWDPRRA 168


>gi|4504849 potassium channel, subfamily K, member 3 [Homo sapiens]
          Length = 394

 Score =  135 bits (341), Expect = 4e-32
 Identities = 90/248 (36%), Positives = 126/248 (50%), Gaps = 20/248 (8%)

Query: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
           R L L++    YLL+GA +F  LE + E   R + +L +      Y  L Q   E+  +V
Sbjct: 7   RTLALIVCTFTYLLVGAAVFDALESEPELIERQRLELRQQELRARYN-LSQGGYEELERV 65

Query: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
           ++      + P         W F  SF+FA TV+TTIGYG+ APST+ G+VFC+FYALLG
Sbjct: 66  VLR-----LKPHKAGVQ---WRFAGSFYFAITVITTIGYGHAAPSTDGGKVFCMFYALLG 117

Query: 133 IPLNVIFLNHLGTGLRA------HLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
           IPL ++    LG  +        H A       R   S    VL +  F  + TL I   
Sbjct: 118 IPLTLVMFQSLGERINTLVRYLLHRAKKGLGMRRADVSMANMVL-IGFFSCISTLCI--- 173

Query: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
               FSH E W+F + +Y+ FITL+TIGFGDYV +  D +      Y + + ++IL GL 
Sbjct: 174 GAAAFSHYEHWTFFQAYYYCFITLTTIGFGDYVALQKDQALQTQPQYVAFSFVYILTGLT 233

Query: 246 WLALILPL 253
            +   L L
Sbjct: 234 VIGAFLNL 241


>gi|7706135 potassium channel, subfamily K, member 9 [Homo sapiens]
          Length = 374

 Score =  131 bits (329), Expect = 9e-31
 Identities = 87/248 (35%), Positives = 130/248 (52%), Gaps = 20/248 (8%)

Query: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQ-WAMEQFVQ 71
           R L L++    YLL+GA +F  LE   E +  ++ + E++R    Y    + +   + V 
Sbjct: 7   RTLSLIVCTFTYLLVGAAVFDALESDHEMREEEKLKAEEIRIKGKYNISSEDYRQLELVI 66

Query: 72  VIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALL 131
           +  E    GV           W F  SF+FA TV+TTIGYG+ AP T+AG+ FC+FYA+L
Sbjct: 67  LQSEPHRAGVQ----------WKFAGSFYFAITVITTIGYGHAAPGTDAGKAFCMFYAVL 116

Query: 132 GIPLNVIFLNHLG----TGLRAHLAAIER-WEDRPRRSQVLQVLGLALFLTLGTLVILIF 186
           GIPL ++    LG    T +R  L  I++    R     +  ++ +  F  +GTL I   
Sbjct: 117 GIPLTLVMFQSLGERMNTFVRYLLKRIKKCCGMRNTDVSMENMVTVGFFSCMGTLCI--- 173

Query: 187 PPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWILLGLA 245
               FS  E WSF   +Y+ FITL+TIGFGDYV + T  +     +Y + + ++IL+GL 
Sbjct: 174 GAAAFSQCEEWSFFHAYYYCFITLTTIGFGDYVALQTKGALQKKPLYVAFSFMYILVGLT 233

Query: 246 WLALILPL 253
            +   L L
Sbjct: 234 VIGAFLNL 241


>gi|11641275 potassium family, subfamily K, member 15 [Homo sapiens]
          Length = 330

 Score =  129 bits (325), Expect = 3e-30
 Identities = 87/252 (34%), Positives = 130/252 (51%), Gaps = 28/252 (11%)

Query: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
           R   L+L  +CYLL+GA +F  LE +AE+  R +  ++K   L            +  ++
Sbjct: 7   RAAGLVLCTLCYLLVGAAVFDALESEAES-GRQRLLVQKRGALRRKFGFSAEDYRELERL 65

Query: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
            ++A       +        W F  SF+FA TV+TTIGYG+ AP T++G+VFC+FYALLG
Sbjct: 66  ALQAEPHRAGRQ--------WKFPGSFYFAITVITTIGYGHAAPGTDSGKVFCMFYALLG 117

Query: 133 IPLNVIFLNHLGTGLRAHLAAI---------ERWEDRPRRSQVLQ-VLGLALFLTLGTLV 182
           IPL ++    LG  L A +  +          RW      + V+  +L  A  L LG   
Sbjct: 118 IPLTLVTFQSLGERLNAVVRRLLLAAKCCLGLRWTCVSTENLVVAGLLACAATLALGA-- 175

Query: 183 ILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYV-VGTDPSKHYISVYRSLAAIWIL 241
                 + FSH EGW+F   +Y+ FITL+TIGFGD+V + +  +      Y + + ++IL
Sbjct: 176 ------VAFSHFEGWTFFHAYYYCFITLTTIGFGDFVALQSGEALQRKLPYVAFSFLYIL 229

Query: 242 LGLAWLALILPL 253
           LGL  +   L L
Sbjct: 230 LGLTVIGAFLNL 241


>gi|16118231 potassium channel, subfamily K, member 7 isoform A
           [Homo sapiens]
          Length = 307

 Score =  112 bits (279), Expect = 5e-25
 Identities = 81/244 (33%), Positives = 126/244 (51%), Gaps = 14/244 (5%)

Query: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72

Query: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132

Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189

Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI--WILLGLAWL 247
              ++G  S     YF F +LSTIG  D + G   S H +  +    A+  ++LLGL  L
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGYLLLGL--L 247

Query: 248 ALIL 251
           A++L
Sbjct: 248 AMLL 251


>gi|11545761 potassium channel, subfamily K, member 12 [Homo
           sapiens]
          Length = 430

 Score =  111 bits (278), Expect = 7e-25
 Identities = 95/326 (29%), Positives = 145/326 (44%), Gaps = 38/326 (11%)

Query: 2   PSAGLCSCWG-------GRVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF 54
           PS   C C         GR + L      YL+ GAT+F  LE   EA++R ++      F
Sbjct: 20  PSCCCCCCRRSHLNEDTGRFVLLAALIGLYLVAGATVFSALESPGEAEARARWGATLRNF 79

Query: 55  LENYTCLDQWAMEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNL 114
              +   +   +  F++    A   GV  + ++  P  WDF  +F+F GTVV+TIG+G  
Sbjct: 80  SAAHGVAEP-ELRAFLRHYEAALAAGV--RADALRP-RWDFPGAFYFVGTVVSTIGFGMT 135

Query: 115 APSTEAGQVFCVFYALLGIPLNVIFLNHLGTGLRAHLAAIERW--EDRPRRSQVLQVL-- 170
            P+T  G+ F + Y L G    ++F N     + + LA I R   E + RRS +L     
Sbjct: 136 TPATVGGKAFLIAYGLFGCAGTILFFNLFLERIISLLAFIMRACRERQLRRSGLLPATFR 195

Query: 171 -GLAL----------------FLTLGTLVILIF--PPMVFSHVEGWSFSEGFYFAFITLS 211
            G AL                 L LG   +L+      +++ VEGW + +  YF F+T S
Sbjct: 196 RGSALSEADSLAGWKPSVYHVLLILGLFAVLLSCCASAMYTSVEGWDYVDSLYFCFVTFS 255

Query: 212 TIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQ 271
           TIGFGD V     +     +YR    ++ILLG+  +  +  +  +L+ +     L  L  
Sbjct: 256 TIGFGDLVSSQHAAYRNQGLYRLGNFLFILLGVCCIYSLFNVISILIKQVLNWMLRKLSC 315

Query: 272 GCGAKAAPGRRPRRGSTAARGVQVTP 297
            C A+  P      G+  AR   +TP
Sbjct: 316 RCCARCCPA----PGAPLARRNAITP 337


>gi|16306555 potassium channel, subfamily K, member 13 [Homo
           sapiens]
          Length = 408

 Score =  110 bits (275), Expect = 2e-24
 Identities = 81/286 (28%), Positives = 136/286 (47%), Gaps = 31/286 (10%)

Query: 13  RVLPLLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCLDQWAMEQFVQV 72
           R L L    V YLL GA +F  LE   E Q++ +++     F   +  L +  +  F++ 
Sbjct: 19  RFLLLAALIVLYLLGGAAVFSALELAHERQAKQRWEERLANFSRGHN-LSRDELRGFLRH 77

Query: 73  IMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLG 132
             EA   G+  + ++  P  WDF  +F+F GTVV+TIG+G   P+T  G++F +FY L+G
Sbjct: 78  YEEATRAGI--RVDNVRP-RWDFTGAFYFVGTVVSTIGFGMTTPATVGGKIFLIFYGLVG 134

Query: 133 IPLNVIFLNHLGTGL---------RAHLAAIERWEDRPRRS-------QVLQVLG----- 171
               ++F N     L           H   + R    P+ S       +V  + G     
Sbjct: 135 CSSTILFFNLFLERLITIIAYIMKSCHQRQLRRRGALPQESLKDAGQCEVDSLAGWKPSV 194

Query: 172 --LALFLTLGTLVILIFPPMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYI 229
             + L L   +++I      +++ +EGWS+ +  YF F+  STIGFGD V  +  + HY 
Sbjct: 195 YYVMLILCTASILISCCASAMYTPIEGWSYFDSLYFCFVAFSTIGFGDLV--SSQNAHYE 252

Query: 230 S--VYRSLAAIWILLGLAWLALILPLGPLLLHRCCQLWLLSLRQGC 273
           S  +YR    ++IL+G+  +  +  +  +L+ +     L  +  GC
Sbjct: 253 SQGLYRFANFVFILMGVCCIYSLFNVISILIKQSLNWILRKMDSGC 298


>gi|16118235 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score =  108 bits (270), Expect = 6e-24
 Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 14/241 (5%)

Query: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72

Query: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132

Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189

Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI----WILLGLA 245
              ++G  S     YF F +LSTIG  D + G   S H +  +    A+      L G A
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGGGTSLQGTA 249

Query: 246 W 246
           W
Sbjct: 250 W 250


>gi|16118233 potassium channel, subfamily K, member 7 isoform B
           [Homo sapiens]
          Length = 252

 Score =  108 bits (270), Expect = 6e-24
 Identities = 78/241 (32%), Positives = 119/241 (49%), Gaps = 14/241 (5%)

Query: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72

Query: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132

Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189

Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAI----WILLGLA 245
              ++G  S     YF F +LSTIG  D + G   S H +  +    A+      L G A
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLHPVIYHLGQLALLGGGTSLQGTA 249

Query: 246 W 246
           W
Sbjct: 250 W 250


>gi|5031821 potassium channel, subfamily K, member 7 isoform C [Homo
           sapiens]
          Length = 257

 Score =  107 bits (267), Expect = 1e-23
 Identities = 73/218 (33%), Positives = 111/218 (50%), Gaps = 10/218 (4%)

Query: 17  LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRF-LENYTCLDQWAMEQFVQVIME 75
           L++A++  L LGA +FQ LE     + + + + E   F  E+  CL   A+E+ +   + 
Sbjct: 13  LVVAHLLALGLGAVVFQALEGPPACRLQAELRAELAAFQAEHRACLPPGALEELLGTALA 72

Query: 76  AWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPL 135
               GV+  GNS+    WD  S+  FA +++TT GYG++AP +  G+ FC+ YA LG+P 
Sbjct: 73  TQAHGVSTLGNSSEGRTWDLPSALLFAASILTTTGYGHMAPLSPGGKAFCMVYAALGLPA 132

Query: 136 N---VIFLNH--LGTGLRAHLAAIERWEDRPRRSQVLQVLGLALFLTLGTLVILIFPPMV 190
           +   V  L H  L    R        W+  P R+ +LQ + L L L   + V+L  P +V
Sbjct: 133 SLALVATLRHCLLPVLSRPRAWVAVHWQLSPARAALLQAVALGL-LVASSFVLL--PALV 189

Query: 191 FSHVEG-WSFSEGFYFAFITLSTIGFGDYVVGTDPSKH 227
              ++G  S     YF F +LSTIG  D + G   S H
Sbjct: 190 LWGLQGDCSLLGAVYFCFSSLSTIGLEDLLPGRGRSLH 227


>gi|32469495 potassium channel, subfamily K, member 18 [Homo
           sapiens]
          Length = 384

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 45/139 (32%), Positives = 69/139 (49%), Gaps = 10/139 (7%)

Query: 12  GRVLP---LLLAYVCYLLLGATIFQLLERQAEAQSRDQFQLEKLRFLENYTCL---DQWA 65
           G++ P    L   V Y L+GA +F  +E      + D  + EK  FLE    +    +  
Sbjct: 18  GKLFPGLCFLCFLVTYALVGAVVFSAIEDGQVLVAADDGEFEK--FLEELCRILNCSETV 75

Query: 66  MEQFVQVIMEAWVKGVNPKGNSTNPSNWDFGSSFFFAGTVVTTIGYGNLAPSTEAGQVFC 125
           +E   Q + +  ++ V P+  +   ++W F SS FF  TV +T+GYG + P T  G+  C
Sbjct: 76  VEDRKQDL-QGHLQKVKPQWFNRT-THWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKYLC 133

Query: 126 VFYALLGIPLNVIFLNHLG 144
           + YAL GIPL  + L   G
Sbjct: 134 MLYALFGIPLMFLVLTDTG 152



 Score = 36.6 bits (83), Expect = 0.029
 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 4/69 (5%)

Query: 168 QVLGLALFLTLGTLVILIFPPMVFSHVEGWS----FSEGFYFAFITLSTIGFGDYVVGTD 223
           QV  L + L +  L++  +     + +  W     F   FYF F+TL+TIGFGD V+   
Sbjct: 275 QVERLDIPLPIIALIVFAYISCAAAILPFWETQLDFENAFYFCFVTLTTIGFGDTVLEHP 334

Query: 224 PSKHYISVY 232
               + S+Y
Sbjct: 335 NFFLFFSIY 343



 Score = 29.6 bits (65), Expect = 3.5
 Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 7/64 (10%)

Query: 188 PMVFSHVEGWSFSEGFYFAFITLSTIGFGDYVVGTDPSKHYISVYRSLAAIWILLGLAWL 247
           P  F+    WSF    +F     ST+G+G     T   K+       L  ++ L G+  +
Sbjct: 92  PQWFNRTTHWSFLSSLFFCCTVFSTVGYGYIYPVTRLGKY-------LCMLYALFGIPLM 144

Query: 248 ALIL 251
            L+L
Sbjct: 145 FLVL 148


>gi|4504831 potassium voltage-gated channel, subfamily H, member 1
           isoform 2 [Homo sapiens]
          Length = 962

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 86  NSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNV 137
           N +    W+ G        SS +F  T +T++G+GN+APST+  ++F V   ++G  L  
Sbjct: 406 NGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYA 465

Query: 138 IFLNHLGTGLRAHLAAIERWED 159
               ++ T  +   A   R+ +
Sbjct: 466 TIFGNVTTIFQQMYANTNRYHE 487


>gi|27437001 potassium voltage-gated channel, subfamily H, member 1
           isoform 1 [Homo sapiens]
          Length = 989

 Score = 41.6 bits (96), Expect = 0.001
 Identities = 22/82 (26%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 86  NSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIPLNV 137
           N +    W+ G        SS +F  T +T++G+GN+APST+  ++F V   ++G  L  
Sbjct: 433 NGSGSGKWEGGPSKNSVYISSLYFTMTSLTSVGFGNIAPSTDIEKIFAVAIMMIGSLLYA 492

Query: 138 IFLNHLGTGLRAHLAAIERWED 159
               ++ T  +   A   R+ +
Sbjct: 493 TIFGNVTTIFQQMYANTNRYHE 514


>gi|22024390 potassium voltage-gated channel, subfamily H, member 5
           isoform 1 [Homo sapiens]
          Length = 988

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 8/85 (9%)

Query: 83  PKGNSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
           P   +T+   W+ G        SS +F  T +TTIG+GN+AP+T+  ++F V   ++G  
Sbjct: 399 PYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSL 458

Query: 135 LNVIFLNHLGTGLRAHLAAIERWED 159
           L      ++ T  +   A   R+ +
Sbjct: 459 LYATIFGNVTTIFQQMYANTNRYHE 483


>gi|27886648 potassium voltage-gated channel, subfamily H, member 5
           isoform 2 [Homo sapiens]
          Length = 624

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 24/85 (28%), Positives = 42/85 (49%), Gaps = 8/85 (9%)

Query: 83  PKGNSTNPSNWDFG--------SSFFFAGTVVTTIGYGNLAPSTEAGQVFCVFYALLGIP 134
           P   +T+   W+ G        SS +F  T +TTIG+GN+AP+T+  ++F V   ++G  
Sbjct: 341 PYRYNTSAGIWEGGPSKDSLYVSSLYFTMTSLTTIGFGNIAPTTDVEKMFSVAMMMVGSL 400

Query: 135 LNVIFLNHLGTGLRAHLAAIERWED 159
           L      ++ T  +   A   R+ +
Sbjct: 401 LYATIFGNVTTIFQQMYANTNRYHE 425


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.327    0.142    0.460 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,161,830
Number of Sequences: 37866
Number of extensions: 529671
Number of successful extensions: 2159
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 98
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1888
Number of HSP's gapped (non-prelim): 191
length of query: 309
length of database: 18,247,518
effective HSP length: 102
effective length of query: 207
effective length of database: 14,385,186
effective search space: 2977733502
effective search space used: 2977733502
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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