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Search of human proteins with 83582802
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|83582802 beta-defensin 128 [Homo sapiens]
(93 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|83582802 beta-defensin 128 [Homo sapiens] 194 2e-50
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens] 62 1e-10
gi|16905373 beta-defensin 118 [Homo sapiens] 49 9e-07
gi|23503331 defensin, beta 123 precursor [Homo sapiens] 41 2e-04
gi|83582798 beta-defensin 115 [Homo sapiens] 40 5e-04
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens] 35 0.010
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens] 35 0.013
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens] 35 0.013
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens] 35 0.013
gi|46409558 beta-defensin 32 precursor [Homo sapiens] 35 0.017
gi|58865339 defensin, beta 121 [Homo sapiens] 35 0.017
gi|82734223 beta-defensin 124 [Homo sapiens] 33 0.065
gi|116517226 beta-defensin 135 [Homo sapiens] 32 0.084
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens] 32 0.11
gi|13624333 defensin, beta 126 preproprotein [Homo sapiens] 32 0.14
gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo ... 30 0.32
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens] 30 0.42
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap... 29 0.71
gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap... 29 0.71
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi... 29 0.71
gi|103485139 defensin, beta 104A precursor [Homo sapiens] 28 1.2
gi|103485137 defensin, beta 104B precursor [Homo sapiens] 28 1.2
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens] 28 2.1
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens] 28 2.1
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens] 28 2.1
gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens] 27 2.7
gi|22748611 defensin, beta 106A precursor [Homo sapiens] 27 2.7
gi|50344744 beta-defensin 108B [Homo sapiens] 27 2.7
gi|18250304 beta defensin 129 precursor [Homo sapiens] 27 2.7
gi|103485143 defensin, beta 106B precursor [Homo sapiens] 27 2.7
>gi|83582802 beta-defensin 128 [Homo sapiens]
Length = 93
Score = 194 bits (492), Expect = 2e-50
Identities = 93/93 (100%), Positives = 93/93 (100%)
Query: 1 MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK 60
MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK
Sbjct: 1 MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK 60
Query: 61 KHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV 93
KHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV
Sbjct: 61 KHVSFKKPHQHSGEKLSVLQDYIILPTITIFTV 93
>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
Length = 99
Score = 62.0 bits (149), Expect = 1e-10
Identities = 35/87 (40%), Positives = 52/87 (59%), Gaps = 2/87 (2%)
Query: 1 MKLFLVLIILLFEVLTDGARLKKCFNK-VTGYCRKKCKVGERYEIGCLSGKLCCANDEEE 59
M LF+++ ILLF+ T +LKKC+N V G+CRK C+V E E C +G+ CC N +E
Sbjct: 1 MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCLNIKEL 60
Query: 60 KKHVSFKKPHQHSGEKLSV-LQDYIIL 85
+ KP + L++ LQDY+ +
Sbjct: 61 EACKKITKPPRPKPATLALTLQDYVTI 87
>gi|16905373 beta-defensin 118 [Homo sapiens]
Length = 123
Score = 48.9 bits (115), Expect = 9e-07
Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%)
Query: 1 MKLFLV---LIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDE 57
MKL L+ +++LL +V+ + KKC+N+ +G+CRK+CK GE + C + + CC
Sbjct: 1 MKLLLLALPMLVLLPQVIPAYSGEKKCWNR-SGHCRKQCKDGEAVKDTCKNLRACCIPSN 59
Query: 58 EEKKHVSFKKPHQHSGEKLSVLQDYI 83
E+ + V P S ++ D +
Sbjct: 60 EDHRRVPATSPTPLSDSTPGIIDDIL 85
>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
Length = 67
Score = 40.8 bits (94), Expect = 2e-04
Identities = 22/63 (34%), Positives = 36/63 (57%), Gaps = 4/63 (6%)
Query: 1 MKLFLVL--IILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEE 58
MKL L+ ++LL LT G ++C+N + G CR +C ER + C++ K+CC +
Sbjct: 1 MKLLLLTLTVLLLLSQLTPGGT-QRCWN-LYGKCRYRCSKKERVYVYCINNKMCCVKPKY 58
Query: 59 EKK 61
+ K
Sbjct: 59 QPK 61
>gi|83582798 beta-defensin 115 [Homo sapiens]
Length = 88
Score = 39.7 bits (91), Expect = 5e-04
Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 3/66 (4%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK-K 61
L LV++++L + DG +++C+ TG CRK CK ER + C +CC E++K
Sbjct: 18 LALVVLVVLAQTAPDGW-IRRCYYG-TGRCRKSCKEIERKKEKCGEKHICCVPKEKDKLS 75
Query: 62 HVSFKK 67
H+ +K
Sbjct: 76 HIHDQK 81
>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
Length = 156
Score = 35.4 bits (80), Expect = 0.010
Identities = 28/101 (27%), Positives = 41/101 (40%), Gaps = 16/101 (15%)
Query: 3 LFLVLII--LLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCAN--DEE 58
L L II LL V +KC+ G+CR++C ERY + C + CC + E
Sbjct: 4 LMLTFIICGLLTRVTKGSFEPQKCWKNNVGHCRRRCLDTERYILLCRNKLSCCISIISHE 63
Query: 59 EKKHVSFKKPH------------QHSGEKLSVLQDYIILPT 87
+ +F H +G +S+L D I T
Sbjct: 64 YTRRPAFPVIHLEDITLDYSDVDSFTGSPVSMLNDLITFDT 104
>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 35.0 bits (79), Expect = 0.013
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 15 LTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L+ R +K + G+CRK CK GE+ + C +G CC
Sbjct: 8 LSSVCRSQKSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 35.0 bits (79), Expect = 0.013
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 15 LTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L+ R +K + G+CRK CK GE+ + C +G CC
Sbjct: 8 LSSVCRSQKSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
Length = 53
Score = 35.0 bits (79), Expect = 0.013
Identities = 15/39 (38%), Positives = 22/39 (56%)
Query: 15 LTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L+ R +K + G+CRK CK GE+ + C +G CC
Sbjct: 8 LSSVCRSQKSCWIIKGHCRKNCKPGEQVKKPCKNGDYCC 46
>gi|46409558 beta-defensin 32 precursor [Homo sapiens]
Length = 95
Score = 34.7 bits (78), Expect = 0.017
Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 4/54 (7%)
Query: 4 FLVLII----LLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
FL+L++ L +V+ A KC + GYCR C GE C + + CC
Sbjct: 3 FLLLVLAALGFLTQVIPASAGGSKCVSNTPGYCRTCCHWGETALFMCNASRKCC 56
>gi|58865339 defensin, beta 121 [Homo sapiens]
Length = 76
Score = 34.7 bits (78), Expect = 0.017
Identities = 20/55 (36%), Positives = 29/55 (52%), Gaps = 2/55 (3%)
Query: 1 MKLFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCAN 55
MKL L+L+ + +L + KC+ K +G CR CK E Y I C + CC +
Sbjct: 1 MKLLLLLLTVTL-LLAQVTPVMKCWGK-SGRCRTTCKESEVYYILCKTEAKCCVD 53
>gi|82734223 beta-defensin 124 [Homo sapiens]
Length = 71
Score = 32.7 bits (73), Expect = 0.065
Identities = 18/51 (35%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
LFLV +++L V + + K+C+ K G C+ C E Y C LCC
Sbjct: 6 LFLVALLVLGHVPSGRSEFKRCW-KGQGACQTYCTRQETYMHLCPDASLCC 55
>gi|116517226 beta-defensin 135 [Homo sapiens]
Length = 77
Score = 32.3 bits (72), Expect = 0.084
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 7/60 (11%)
Query: 3 LFLVLIILLFEVLTD----GARLKKCFN---KVTGYCRKKCKVGERYEIGCLSGKLCCAN 55
L LV++ LLF V ++K F ++ G CR KC E+Y I C + LCC N
Sbjct: 8 LALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCVN 67
>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
Length = 84
Score = 32.0 bits (71), Expect = 0.11
Identities = 16/52 (30%), Positives = 28/52 (53%), Gaps = 2/52 (3%)
Query: 3 LFLVLIILLFEVLTDGAR-LKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
LFL +++ + E + G R + +C +G CR CK E+ + C + + CC
Sbjct: 6 LFLAILLAIEEPVISGKRHILRCMGN-SGICRASCKKNEQPYLYCRNCQSCC 56
>gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]
Length = 111
Score = 31.6 bits (70), Expect = 0.14
Identities = 15/38 (39%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 5 LVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERY 42
L + +LL ++++ +KKC N V G C+KKCK E +
Sbjct: 8 LAVFMLLAQLVSGNWYVKKCLNDV-GICKKKCKPEEMH 44
>gi|239742274 PREDICTED: hypothetical protein XP_002342470 [Homo
sapiens]
Length = 87
Score = 30.4 bits (67), Expect = 0.32
Identities = 22/61 (36%), Positives = 29/61 (47%), Gaps = 9/61 (14%)
Query: 1 MKLFLVLIILLFEVLTD-------GARLKKCFNKVTGYCRKK-CKVGERYEIGCLSGKLC 52
M+L L+L+ILLF +L G C N ++G CR+ CKV E C C
Sbjct: 1 MRLHLLLLILLFSILLSPGNKGGLGPAEGHCLN-LSGVCRRDVCKVVEDQIGACRRKMKC 59
Query: 53 C 53
C
Sbjct: 60 C 60
>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
Length = 88
Score = 30.0 bits (66), Expect = 0.42
Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 4/51 (7%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L+L L ILL + + +C+ + G+CR CK GE I C + K CC
Sbjct: 4 LYLFLAILL--AIEEPVISVECW--MDGHCRLLCKDGEDSIIRCRNRKRCC 50
>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
sapiens]
Length = 867
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 40 ERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILP 86
E YE CL+ A DEEE+ + KK H H ++ V Q + P
Sbjct: 734 EEYE-SCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEP 779
>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 40 ERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILP 86
E YE CL+ A DEEE+ + KK H H ++ V Q + P
Sbjct: 734 EEYE-SCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEP 779
>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
Length = 897
Score = 29.3 bits (64), Expect = 0.71
Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 1/47 (2%)
Query: 40 ERYEIGCLSGKLCCANDEEEKKHVSFKKPHQHSGEKLSVLQDYIILP 86
E YE CL+ A DEEE+ + KK H H ++ V Q + P
Sbjct: 734 EEYE-SCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEP 779
>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
Length = 72
Score = 28.5 bits (62), Expect = 1.2
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGY----CRKKCKVGERYEIG-CLSGKLCCANDE 57
L L + +LL++ L + + +++ GY CRKKC+ + Y IG C + CC
Sbjct: 6 LLLAISLLLYQDLPVRSEFE--LDRICGYGTARCRKKCR-SQEYRIGRCPNTYACCLRKW 62
Query: 58 EE 59
+E
Sbjct: 63 DE 64
>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
Length = 72
Score = 28.5 bits (62), Expect = 1.2
Identities = 19/62 (30%), Positives = 32/62 (51%), Gaps = 8/62 (12%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGY----CRKKCKVGERYEIG-CLSGKLCCANDE 57
L L + +LL++ L + + +++ GY CRKKC+ + Y IG C + CC
Sbjct: 6 LLLAISLLLYQDLPVRSEFE--LDRICGYGTARCRKKCR-SQEYRIGRCPNTYACCLRKW 62
Query: 58 EE 59
+E
Sbjct: 63 DE 64
>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/51 (25%), Positives = 22/51 (43%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L + + +VL + K+ + G CR C E + CL+ + CC
Sbjct: 16 LLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66
>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
Length = 83
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/51 (25%), Positives = 22/51 (43%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L + + +VL + K+ + G CR C E + CL+ + CC
Sbjct: 16 LLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66
>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
Length = 73
Score = 27.7 bits (60), Expect = 2.1
Identities = 13/51 (25%), Positives = 22/51 (43%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L + + +VL + K+ + G CR C E + CL+ + CC
Sbjct: 6 LLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 56
>gi|11034819 nuclear receptor interacting protein 3 [Homo sapiens]
Length = 241
Score = 27.3 bits (59), Expect = 2.7
Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 5/38 (13%)
Query: 43 EIGCLSG--KLCCANDEEEKKHVSFKKPHQHSGEKLSV 78
+ GCL L C + K+HV K H+H GEKLS+
Sbjct: 124 DTGCLYNLISLACVDRLGLKEHV---KSHKHEGEKLSL 158
>gi|22748611 defensin, beta 106A precursor [Homo sapiens]
Length = 65
Score = 27.3 bits (59), Expect = 2.7
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 1 MKLFLVLIILLFEVLTDGARL---KKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
M+ FL L +LF LT +KC NK+ G C+ C E C CC
Sbjct: 1 MRTFLFLFAVLF-FLTPAKNAFFDEKC-NKLKGTCKNNCGKNEELIALCQKSLKCC 54
>gi|50344744 beta-defensin 108B [Homo sapiens]
Length = 73
Score = 27.3 bits (59), Expect = 2.7
Identities = 13/51 (25%), Positives = 22/51 (43%)
Query: 3 LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
L + + +VL + K+ + G CR C E + CL+ + CC
Sbjct: 6 LLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCC 56
>gi|18250304 beta defensin 129 precursor [Homo sapiens]
Length = 183
Score = 27.3 bits (59), Expect = 2.7
Identities = 17/53 (32%), Positives = 27/53 (50%), Gaps = 2/53 (3%)
Query: 8 IILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK 60
++L ++V T+ L++C + G CR C V E+ EI K CC + K
Sbjct: 11 LMLQYQVNTEFIGLRRCLMGL-GRCRDHCNVDEK-EIQKCKMKKCCVGPKVVK 61
>gi|103485143 defensin, beta 106B precursor [Homo sapiens]
Length = 65
Score = 27.3 bits (59), Expect = 2.7
Identities = 19/56 (33%), Positives = 24/56 (42%), Gaps = 5/56 (8%)
Query: 1 MKLFLVLIILLFEVLTDGARL---KKCFNKVTGYCRKKCKVGERYEIGCLSGKLCC 53
M+ FL L +LF LT +KC NK+ G C+ C E C CC
Sbjct: 1 MRTFLFLFAVLF-FLTPAKNAFFDEKC-NKLKGTCKNNCGKNEELIALCQKSLKCC 54
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.143 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,661,491
Number of Sequences: 37866
Number of extensions: 148657
Number of successful extensions: 447
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 25
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 416
Number of HSP's gapped (non-prelim): 41
length of query: 93
length of database: 18,247,518
effective HSP length: 64
effective length of query: 29
effective length of database: 15,824,094
effective search space: 458898726
effective search space used: 458898726
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Search text |
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.