Search of human proteins with 83582798

Search of human proteins with 83582798

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|83582798 beta-defensin 115 [Homo sapiens]
         (88 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|83582798 beta-defensin 115 [Homo sapiens]                          188   9e-49
gi|16905373 beta-defensin 118 [Homo sapiens]                           51   2e-07
gi|23503331 defensin, beta 123 precursor [Homo sapiens]                44   3e-05
gi|58865339 defensin, beta 121 [Homo sapiens]                          42   8e-05
gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]            42   1e-04
gi|103485139 defensin, beta 104A precursor [Homo sapiens]              40   4e-04
gi|103485137 defensin, beta 104B precursor [Homo sapiens]              40   4e-04
gi|83582802 beta-defensin 128 [Homo sapiens]                           40   5e-04
gi|18250304 beta defensin 129 precursor [Homo sapiens]                 39   0.001
gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]              38   0.002
gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]              38   0.002
gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]              38   0.002
gi|83582800 beta-defensin 116 [Homo sapiens]                           35   0.017
gi|116517226 beta-defensin 135 [Homo sapiens]                          34   0.028
gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]      33   0.037
gi|82734223 beta-defensin 124 [Homo sapiens]                           33   0.048
gi|22748617 defensin, beta 105A precursor [Homo sapiens]               33   0.063
gi|103485141 defensin, beta 105B precursor [Homo sapiens]              33   0.063
gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]            32   0.082
gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]            32   0.082
gi|82734219 beta-defensin 114 [Homo sapiens]                           30   0.31 
gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]            29   0.70 
gi|50344744 beta-defensin 108B [Homo sapiens]                          29   0.70 
gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]                   29   0.91 
gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]                   29   0.91 
gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]      29   0.91 
gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]            28   1.5  
gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]            27   4.5  
gi|4505393 nerve growth factor receptor precursor [Homo sapiens]       26   7.7  
gi|38454326 CD38 antigen [Homo sapiens]                                26   7.7  

>gi|83582798 beta-defensin 115 [Homo sapiens]
          Length = 88

 Score =  188 bits (477), Expect = 9e-49
 Identities = 88/88 (100%), Positives = 88/88 (100%)

Query: 1  MLPDHFSPLSGDIKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCG 60
          MLPDHFSPLSGDIKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCG
Sbjct: 1  MLPDHFSPLSGDIKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCG 60

Query: 61 EKHICCVPKEKDKLSHIHDQKETSELYI 88
          EKHICCVPKEKDKLSHIHDQKETSELYI
Sbjct: 61 EKHICCVPKEKDKLSHIHDQKETSELYI 88


>gi|16905373 beta-defensin 118 [Homo sapiens]
          Length = 123

 Score = 50.8 bits (120), Expect = 2e-07
 Identities = 24/61 (39%), Positives = 36/61 (59%), Gaps = 1/61 (1%)

Query: 13 IKLSVLALVVLVVLAQTAPD-GWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEK 71
          +KL +LAL +LV+L Q  P     ++C+  +G CRK CK+ E  K+ C     CC+P  +
Sbjct: 1  MKLLLLALPMLVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKDTCKNLRACCIPSNE 60

Query: 72 D 72
          D
Sbjct: 61 D 61


>gi|23503331 defensin, beta 123 precursor [Homo sapiens]
          Length = 67

 Score = 43.9 bits (102), Expect = 3e-05
 Identities = 25/64 (39%), Positives = 36/64 (56%), Gaps = 6/64 (9%)

Query: 13 IKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV----- 67
          +KL +L L VL++L+Q  P G  +RC+   G+CR  C + ER    C    +CCV     
Sbjct: 1  MKLLLLTLTVLLLLSQLTPGG-TQRCWNLYGKCRYRCSKKERVYVYCINNKMCCVKPKYQ 59

Query: 68 PKEK 71
          PKE+
Sbjct: 60 PKER 63


>gi|58865339 defensin, beta 121 [Homo sapiens]
          Length = 76

 Score = 42.4 bits (98), Expect = 8e-05
 Identities = 28/76 (36%), Positives = 42/76 (55%), Gaps = 7/76 (9%)

Query: 13 IKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV-PK-- 69
          +KL +L L V ++LAQ  P   + +C+  +GRCR +CKE E     C  +  CCV PK  
Sbjct: 1  MKLLLLLLTVTLLLAQVTP---VMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYV 57

Query: 70 -EKDKLSHIHDQKETS 84
            K KL+  +   E++
Sbjct: 58 PVKPKLTDTNTSLEST 73


>gi|13624333 defensin, beta 126 preproprotein [Homo sapiens]
          Length = 111

 Score = 41.6 bits (96), Expect = 1e-04
 Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 5/64 (7%)

Query: 13 IKLSVLALVVLVVLAQTAPDGW-IRRCYYGTGRCRKSCKEIERKKEK----CGEKHICCV 67
          +K  +  L V ++LAQ     W +++C    G C+K CK  E   +     CG++  CCV
Sbjct: 1  MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPEEMHVKNGWAMCGKQRDCCV 60

Query: 68 PKEK 71
          P ++
Sbjct: 61 PADR 64


>gi|103485139 defensin, beta 104A precursor [Homo sapiens]
          Length = 72

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 17 VLALVVLVVLAQTAPDG----WIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72
          VL L + ++L Q  P        R C YGT RCRK C+  E +  +C   + CC+ K  +
Sbjct: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDE 64

Query: 73 KL 74
           L
Sbjct: 65 SL 66


>gi|103485137 defensin, beta 104B precursor [Homo sapiens]
          Length = 72

 Score = 40.0 bits (92), Expect = 4e-04
 Identities = 22/62 (35%), Positives = 31/62 (50%), Gaps = 4/62 (6%)

Query: 17 VLALVVLVVLAQTAPDG----WIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72
          VL L + ++L Q  P        R C YGT RCRK C+  E +  +C   + CC+ K  +
Sbjct: 5  VLLLAISLLLYQDLPVRSEFELDRICGYGTARCRKKCRSQEYRIGRCPNTYACCLRKWDE 64

Query: 73 KL 74
           L
Sbjct: 65 SL 66


>gi|83582802 beta-defensin 128 [Homo sapiens]
          Length = 93

 Score = 39.7 bits (91), Expect = 5e-04
 Identities = 23/66 (34%), Positives = 38/66 (57%), Gaps = 3/66 (4%)

Query: 18 LALVVLVVLAQTAPDGW-IRRCYYG-TGRCRKSCKEIERKKEKCGEKHICCVPKEKDKLS 75
          L LV++++L +   DG  +++C+   TG CRK CK  ER +  C    +CC   E++K  
Sbjct: 3  LFLVLIILLFEVLTDGARLKKCFNKVTGYCRKKCKVGERYEIGCLSGKLCCANDEEEK-K 61

Query: 76 HIHDQK 81
          H+  +K
Sbjct: 62 HVSFKK 67


>gi|18250304 beta defensin 129 precursor [Homo sapiens]
          Length = 183

 Score = 38.5 bits (88), Expect = 0.001
 Identities = 16/35 (45%), Positives = 20/35 (57%)

Query: 35 IRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPK 69
          +RRC  G GRCR  C   E++ +KC  K  C  PK
Sbjct: 24 LRRCLMGLGRCRDHCNVDEKEIQKCKMKKCCVGPK 58


>gi|239757478 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 36 RRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72
          + C+   G CRK+CK  E+ K+ C     CC+P   D
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCCIPSNTD 52


>gi|239751980 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 36 RRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72
          + C+   G CRK+CK  E+ K+ C     CC+P   D
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCCIPSNTD 52


>gi|239746467 PREDICTED: defensin, beta 117 [Homo sapiens]
          Length = 53

 Score = 37.7 bits (86), Expect = 0.002
 Identities = 14/37 (37%), Positives = 20/37 (54%)

Query: 36 RRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKD 72
          + C+   G CRK+CK  E+ K+ C     CC+P   D
Sbjct: 16 KSCWIIKGHCRKNCKPGEQVKKPCKNGDYCCIPSNTD 52


>gi|83582800 beta-defensin 116 [Homo sapiens]
          Length = 102

 Score = 34.7 bits (78), Expect = 0.017
 Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 11/66 (16%)

Query: 13 IKLSVLALVVLVVLAQTAPDGWIRR-----------CYYGTGRCRKSCKEIERKKEKCGE 61
          +K  ++ + +L++LAQ  P G  R            C    G CR +C+E E +   C  
Sbjct: 4  MKPCLMTIAILMILAQKTPGGLFRSHNGKSREPWNPCELYQGMCRNACREYEIQYLTCPN 63

Query: 62 KHICCV 67
             CC+
Sbjct: 64 DQKCCL 69


>gi|116517226 beta-defensin 135 [Homo sapiens]
          Length = 77

 Score = 33.9 bits (76), Expect = 0.028
 Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 9/60 (15%)

Query: 17 VLALVVLVVL-----AQTAPDGWIRR----CYYGTGRCRKSCKEIERKKEKCGEKHICCV 67
          +LALVVL +L      ++ P+ +I++    C+   G CR  C + E+ +  C   H+CCV
Sbjct: 7  LLALVVLNLLFYVPPGRSGPNVYIQKIFASCWRLQGTCRPKCLKNEQYRILCDTIHLCCV 66


>gi|37704382 defensin, beta 119 isoform a precursor [Homo sapiens]
          Length = 84

 Score = 33.5 bits (75), Expect = 0.037
 Identities = 19/57 (33%), Positives = 28/57 (49%), Gaps = 2/57 (3%)

Query: 13 IKLSVLALVVLVVLAQTAPDG--WIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV 67
          +KL  L L +L+ + +    G   I RC   +G CR SCK+ E+    C     CC+
Sbjct: 1  MKLLYLFLAILLAIEEPVISGKRHILRCMGNSGICRASCKKNEQPYLYCRNCQSCCL 57


>gi|82734223 beta-defensin 124 [Homo sapiens]
          Length = 71

 Score = 33.1 bits (74), Expect = 0.048
 Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 3/53 (5%)

Query: 17 VLALVVLVVLAQTAPDGW--IRRCYYGTGRCRKSCKEIERKKEKCGEKHICCV 67
          +L LV L+VL    P G    +RC+ G G C+  C   E     C +  +CC+
Sbjct: 5  LLFLVALLVLGHV-PSGRSEFKRCWKGQGACQTYCTRQETYMHLCPDASLCCL 56


>gi|22748617 defensin, beta 105A precursor [Homo sapiens]
          Length = 78

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 12/29 (41%), Positives = 15/29 (51%)

Query: 38 CYYGTGRCRKSCKEIERKKEKCGEKHICC 66
          C  G G+CRK C E E+    C    +CC
Sbjct: 46 CKLGRGKCRKECLENEKPDGNCRLNFLCC 74


>gi|103485141 defensin, beta 105B precursor [Homo sapiens]
          Length = 78

 Score = 32.7 bits (73), Expect = 0.063
 Identities = 12/29 (41%), Positives = 15/29 (51%)

Query: 38 CYYGTGRCRKSCKEIERKKEKCGEKHICC 66
          C  G G+CRK C E E+    C    +CC
Sbjct: 46 CKLGRGKCRKECLENEKPDGNCRLNFLCC 74


>gi|239753808 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 32.3 bits (72), Expect = 0.082
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 9  LSGDIKLSVLALVVLVVLAQTAPD-GWIRR-CYYGTGRCRKSCKEIERKKEKCGEKHICC 66
          LS  ++++VL   +   ++Q  P  G  +  C    G CR  C E E    +C     CC
Sbjct: 7  LSSAVRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66

Query: 67 VP 68
          +P
Sbjct: 67 LP 68


>gi|239748372 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 83

 Score = 32.3 bits (72), Expect = 0.082
 Identities = 18/62 (29%), Positives = 28/62 (45%), Gaps = 2/62 (3%)

Query: 9  LSGDIKLSVLALVVLVVLAQTAPD-GWIRR-CYYGTGRCRKSCKEIERKKEKCGEKHICC 66
          LS  ++++VL   +   ++Q  P  G  +  C    G CR  C E E    +C     CC
Sbjct: 7  LSSAVRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCC 66

Query: 67 VP 68
          +P
Sbjct: 67 LP 68


>gi|82734219 beta-defensin 114 [Homo sapiens]
          Length = 69

 Score = 30.4 bits (67), Expect = 0.31
 Identities = 13/34 (38%), Positives = 19/34 (55%), Gaps = 1/34 (2%)

Query: 37 RCYYGTGRCRKSCKEIERKKEKCG-EKHICCVPK 69
          RC    GRC++ C E E++ + C   + ICC  K
Sbjct: 28 RCTKRYGRCKRDCLESEKQIDICSLPRKICCTEK 61


>gi|169166494 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 73

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 13 IKLSVLALVVLVVLAQTAPD-GWIRR-CYYGTGRCRKSCKEIERKKEKCGEKHICCVP 68
          ++++VL   +   ++Q  P  G  +  C    G CR  C E E    +C     CC+P
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSRPCCLP 58


>gi|50344744 beta-defensin 108B [Homo sapiens]
          Length = 73

 Score = 29.3 bits (64), Expect = 0.70
 Identities = 16/58 (27%), Positives = 26/58 (44%), Gaps = 2/58 (3%)

Query: 13 IKLSVLALVVLVVLAQTAPD-GWIRR-CYYGTGRCRKSCKEIERKKEKCGEKHICCVP 68
          ++++VL   +   ++Q  P  G  +  C    G CR  C E E    +C     CC+P
Sbjct: 1  MRIAVLLFAIFFFMSQVLPARGKFKEICERPNGSCRDFCLETEIHVGRCLNSQPCCLP 58


>gi|190341022 tetraspanin 14 isoform 2 [Homo sapiens]
          Length = 147

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 13/44 (29%), Positives = 18/44 (40%), Gaps = 7/44 (15%)

Query: 31 PDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKDKL 74
          P+ W    Y+       +C      +EKCG    CCVP    K+
Sbjct: 36 PEDWDLNVYF-------NCSGASYSREKCGVPFSCCVPDPAQKV 72


>gi|190194420 tetraspanin 14 isoform 1 [Homo sapiens]
          Length = 270

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 13/44 (29%), Positives = 18/44 (40%), Gaps = 7/44 (15%)

Query: 31  PDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVPKEKDKL 74
           P+ W    Y+       +C      +EKCG    CCVP    K+
Sbjct: 159 PEDWDLNVYF-------NCSGASYSREKCGVPFSCCVPDPAQKV 195


>gi|23503329 defensin, beta 119 isoform c precursor [Homo sapiens]
          Length = 88

 Score = 28.9 bits (63), Expect = 0.91
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 8/58 (13%)

Query: 13 IKLSVLALVVLVVLAQT--APDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVP 68
          +KL  L L +L+ + +   + + W+       G CR  CK+ E    +C  +  CCVP
Sbjct: 1  MKLLYLFLAILLAIEEPVISVECWM------DGHCRLLCKDGEDSIIRCRNRKRCCVP 52


>gi|21040279 defensin, beta 127 preproprotein [Homo sapiens]
          Length = 99

 Score = 28.1 bits (61), Expect = 1.5
 Identities = 11/55 (20%), Positives = 26/55 (47%), Gaps = 2/55 (3%)

Query: 15 LSVLALVVLVVLAQTAPDGWIRRCY--YGTGRCRKSCKEIERKKEKCGEKHICCV 67
          + +  ++ +++  +      +++C+  Y  G CRK C+  E  +  C     CC+
Sbjct: 1  MGLFMIIAILLFQKPTVTEQLKKCWNNYVQGHCRKICRVNEVPEALCENGRYCCL 55


>gi|76563936 defensin, beta 125 preproprotein [Homo sapiens]
          Length = 156

 Score = 26.6 bits (57), Expect = 4.5
 Identities = 10/25 (40%), Positives = 13/25 (52%)

Query: 43 GRCRKSCKEIERKKEKCGEKHICCV 67
          G CR+ C + ER    C  K  CC+
Sbjct: 33 GHCRRRCLDTERYILLCRNKLSCCI 57


>gi|4505393 nerve growth factor receptor precursor [Homo sapiens]
          Length = 427

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 15/52 (28%), Positives = 22/52 (42%)

Query: 17 VLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEIERKKEKCGEKHICCVP 68
          +L L++L V    A +      Y  +G C K+C   E   + CG     C P
Sbjct: 15 LLLLLLLGVSLGGAKEACPTGLYTHSGECCKACNLGEGVAQPCGANQTVCEP 66


>gi|38454326 CD38 antigen [Homo sapiens]
          Length = 300

 Score = 25.8 bits (55), Expect = 7.7
 Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 15/71 (21%)

Query: 6  FSPLSGD-------------IKLSVLALVVLVVLAQTAPDGWIRRCYYGTGRCRKSCKEI 52
          FSP+SGD             + +S+L L+++VVLA   P  W R+ + G G  ++  + +
Sbjct: 6  FSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVP-RW-RQQWSGPGTTKRFPETV 63

Query: 53 ERKKEKCGEKH 63
            +  K  E H
Sbjct: 64 LARCVKYTEIH 74


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.138    0.439 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 3,884,714
Number of Sequences: 37866
Number of extensions: 167425
Number of successful extensions: 496
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 7
Number of HSP's that attempted gapping in prelim test: 468
Number of HSP's gapped (non-prelim): 33
length of query: 88
length of database: 18,247,518
effective HSP length: 60
effective length of query: 28
effective length of database: 15,975,558
effective search space: 447315624
effective search space used: 447315624
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.