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Search of human proteins with 82534351
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
(758 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|82534351 microtubule-associated protein tau isoform 1 [Homo s... 1533 0.0
gi|178557734 microtubule-associated protein tau isoform 6 [Homo ... 1522 0.0
gi|6754638 microtubule-associated protein tau isoform 2 [Homo sa... 608 e-174
gi|8400711 microtubule-associated protein tau isoform 3 [Homo sa... 608 e-174
gi|178557736 microtubule-associated protein tau isoform 5 [Homo ... 608 e-174
gi|8400715 microtubule-associated protein tau isoform 4 [Homo sa... 520 e-147
gi|87578255 microtubule-associated protein 2 isoform 4 [Homo sap... 332 8e-91
gi|87578394 microtubule-associated protein 2 isoform 5 [Homo sap... 328 1e-89
gi|87578392 microtubule-associated protein 2 isoform 2 [Homo sap... 262 1e-69
gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sap... 259 8e-69
gi|197276600 microtubule-associated protein 4 isoform 4 [Homo sa... 244 2e-64
gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sap... 207 3e-53
gi|47519675 microtubule-associated protein 4 isoform 2 [Homo sap... 206 6e-53
gi|197276602 microtubule-associated protein 4 isoform 5 [Homo sa... 162 1e-39
gi|163965366 nascent polypeptide-associated complex alpha subuni... 96 9e-20
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 78 3e-14
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 78 3e-14
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 78 3e-14
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 78 3e-14
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 78 3e-14
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 75 2e-13
gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax ... 75 3e-13
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 73 1e-12
gi|112821681 G protein-regulated inducer of neurite outgrowth 1 ... 72 2e-12
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 72 2e-12
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 70 9e-12
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 70 9e-12
gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens] 70 9e-12
gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f... 69 1e-11
gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b ... 69 1e-11
>gi|82534351 microtubule-associated protein tau isoform 1 [Homo
sapiens]
Length = 758
Score = 1533 bits (3969), Expect = 0.0
Identities = 758/758 (100%), Positives = 758/758 (100%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
Query: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
Sbjct: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
Query: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
Sbjct: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
Query: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
Sbjct: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
Sbjct: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
Query: 481 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP
Sbjct: 481 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
Query: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD 600
KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD
Sbjct: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLD 600
Query: 601 LSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEK 660
LSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEK
Sbjct: 601 LSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEK 660
Query: 661 LDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDT 720
LDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDT
Sbjct: 661 LDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDT 720
Query: 721 SPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
SPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 721 SPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
>gi|178557734 microtubule-associated protein tau isoform 6 [Homo
sapiens]
Length = 776
Score = 1522 bits (3940), Expect = 0.0
Identities = 758/776 (97%), Positives = 758/776 (97%), Gaps = 18/776 (2%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG
Sbjct: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA
Sbjct: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPA 240
Query: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE
Sbjct: 241 QDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
Query: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA
Sbjct: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPA 360
Query: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS
Sbjct: 361 AAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK
Sbjct: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
Query: 481 GQANATRIPAKTPPAPKTPPSS------------------GEPPKSGDRSGYSSPGSPGT 522
GQANATRIPAKTPPAPKTPPSS GEPPKSGDRSGYSSPGSPGT
Sbjct: 481 GQANATRIPAKTPPAPKTPPSSATKQVQRRPPPAGPRSERGEPPKSGDRSGYSSPGSPGT 540
Query: 523 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 582
PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN
Sbjct: 541 PGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTEN 600
Query: 583 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642
LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL
Sbjct: 601 LKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 660
Query: 643 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 702
GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK
Sbjct: 661 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 720
Query: 703 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 721 TDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 776
>gi|6754638 microtubule-associated protein tau isoform 2 [Homo
sapiens]
Length = 441
Score = 608 bits (1569), Expect = e-174
Identities = 304/331 (91%), Positives = 311/331 (93%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 111 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 170
Query: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 171 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 230
Query: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK
Sbjct: 231 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 290
Query: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 291 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 350
Query: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 351 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 410
Query: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 411 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 441
Score = 268 bits (686), Expect = 1e-71
Identities = 159/315 (50%), Positives = 179/315 (56%), Gaps = 83/315 (26%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQ R ++ GTG +D +
Sbjct: 121 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 142
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
KGA GK + PG K + + R P
Sbjct: 143 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 174
Query: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 175 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 233
Query: 285 DGPSVGRAKGQDAPL 299
PS +++ Q AP+
Sbjct: 234 KSPSSAKSRLQTAPV 248
>gi|8400711 microtubule-associated protein tau isoform 3 [Homo
sapiens]
Length = 383
Score = 608 bits (1569), Expect = e-174
Identities = 304/331 (91%), Positives = 311/331 (93%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
Query: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 113 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172
Query: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK
Sbjct: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 232
Query: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 233 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 292
Query: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 293 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 352
Query: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 353 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 383
Score = 108 bits (269), Expect = 2e-23
Identities = 73/174 (41%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-ESPLQTPTEDGSEEP 59
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK E T +E
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 60 GSETSDAKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDE 117
+ A+ ++D T +GA GK A P P G + G + + +
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG----QKGQANATRIPAK 116
Query: 118 AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGA-PLLPEGPREATRQP 170
P SG+ + G PG G PG+ P P TR+P
Sbjct: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPG-----SPGTPGSRSRTPSLPTPPTREP 165
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/216 (26%), Positives = 78/216 (36%), Gaps = 83/216 (38%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLL 159
G AEEAGIGDTPSLEDEAAGHVTQ
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQA---------------------------------- 67
Query: 160 PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKER-------- 211
R ++ GTG +D + KGA GK +
Sbjct: 68 ----RMVSKSKDGTGSDDKKA-----------------------KGADGKTKIATPRGAA 100
Query: 212 -PGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA-------EG 263
PG K + + R P +PP+ +P G PP++ R S PG P
Sbjct: 101 PPGQKGQANATR-----IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
Query: 264 AIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPL 299
++P P K + + P PS +++ Q AP+
Sbjct: 156 SLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPV 190
Score = 30.4 bits (67), Expect = 6.4
Identities = 76/358 (21%), Positives = 114/358 (31%), Gaps = 59/358 (16%)
Query: 176 EDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPS 235
+D EG A + +GD G + R SK + D ++ D
Sbjct: 33 QDQEGDTDAGLKAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTK 92
Query: 236 KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQ 295
A+P P Q AT IP P P + P S + P G G
Sbjct: 93 IATPRGAAPPGQKGQANATRIPA----KTPPAP---------KTPPSSGEPPKSGDRSGY 139
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPS 355
+P G PG+ P P E K A + P
Sbjct: 140 SSP------------------------GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP- 174
Query: 356 EKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHP 415
K P++A + VP + V K GS + + + + LS
Sbjct: 175 PKSPSSAKSRLQTAPVPMPDLKNV---KSKIGSTENLKHQPGGGKVQIINKKLDLSNVQS 231
Query: 416 TPGSSDPLIQ-PSSPAVCPEPPSSPKHVSSVTSRTGS---------SGAKEMKLKGADGK 465
GS D + P +V + P +S VTS+ GS G E+K + D K
Sbjct: 232 KCGSKDNIKHVPGGGSV--QIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFK 289
Query: 466 TKIATPRGA------APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 517
++ + G+ P G + ++ + KT + KS SG +SP
Sbjct: 290 DRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSP 347
>gi|178557736 microtubule-associated protein tau isoform 5 [Homo
sapiens]
Length = 412
Score = 608 bits (1569), Expect = e-174
Identities = 304/331 (91%), Positives = 311/331 (93%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 82 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 141
Query: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 142 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 201
Query: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK
Sbjct: 202 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 261
Query: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 262 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 321
Query: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 322 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 381
Query: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 382 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 412
Score = 194 bits (494), Expect = 2e-49
Identities = 130/315 (41%), Positives = 150/315 (47%), Gaps = 112/315 (35%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPG 60
Query: 61 SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAG 120
SETSDAKSTPTAE AEEAGIGDTPSLEDEAAG
Sbjct: 61 SETSDAKSTPTAE-----------------------------AEEAGIGDTPSLEDEAAG 91
Query: 121 HVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEG 180
HVTQ R ++ GTG +D +
Sbjct: 92 HVTQ--------------------------------------ARMVSKSKDGTGSDDKKA 113
Query: 181 GRHAPELLKHQLLGDLHQEGPPLKGAGGKER---------PGSKEEVDEDRDVDESSPQD 231
KGA GK + PG K + + R P
Sbjct: 114 -----------------------KGADGKTKIATPRGAAPPGQKGQANATR-----IPAK 145
Query: 232 SPPSKASPAQDGRPPQTAAREATSIPGFPA-------EGAIPLPVDFLSKVSTEIPASEP 284
+PP+ +P G PP++ R S PG P ++P P K + + P
Sbjct: 146 TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPK-KVAVVRTPP 204
Query: 285 DGPSVGRAKGQDAPL 299
PS +++ Q AP+
Sbjct: 205 KSPSSAKSRLQTAPV 219
>gi|8400715 microtubule-associated protein tau isoform 4 [Homo
sapiens]
Length = 352
Score = 520 bits (1338), Expect = e-147
Identities = 267/331 (80%), Positives = 276/331 (83%), Gaps = 31/331 (9%)
Query: 428 SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATR 487
+P++ E V+ +G+ + K KGADGKTKIATPRGAAPPGQKGQANATR
Sbjct: 53 TPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPGQKGQANATR 112
Query: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 547
IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR
Sbjct: 113 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVR 172
Query: 548 TPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
TPPKSPSSAKSRLQTAPVPMPDLKNVK SK
Sbjct: 173 TPPKSPSSAKSRLQTAPVPMPDLKNVK-------------------------------SK 201
Query: 608 CGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 667
GS +N+KH PGGG VQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV
Sbjct: 202 IGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRV 261
Query: 668 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 727
QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN
Sbjct: 262 QSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTSPRHLSN 321
Query: 728 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
VSSTGSIDMVDSPQLATLADEVSASLAKQGL
Sbjct: 322 VSSTGSIDMVDSPQLATLADEVSASLAKQGL 352
Score = 108 bits (269), Expect = 2e-23
Identities = 73/174 (41%), Positives = 87/174 (50%), Gaps = 13/174 (7%)
Query: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK-ESPLQTPTEDGSEEP 59
MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLK E T +E
Sbjct: 1 MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKAEEAGIGDTPSLEDEA 60
Query: 60 GSETSDAKSTPTAEDVTA--PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDE 117
+ A+ ++D T +GA GK A P P G + G + + +
Sbjct: 61 AGHVTQARMVSKSKDGTGSDDKKAKGADGKTKIATPRGAAPPG----QKGQANATRIPAK 116
Query: 118 AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGA-PLLPEGPREATRQP 170
P SG+ + G PG G PG+ P P TR+P
Sbjct: 117 TPPAPKTPPSSGEPPKSGDRSGYSSPG-----SPGTPGSRSRTPSLPTPPTREP 165
Score = 62.0 bits (149), Expect = 2e-09
Identities = 58/216 (26%), Positives = 78/216 (36%), Gaps = 83/216 (38%)
Query: 100 GTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLL 159
G AEEAGIGDTPSLEDEAAGHVTQ
Sbjct: 42 GLKAEEAGIGDTPSLEDEAAGHVTQA---------------------------------- 67
Query: 160 PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKER-------- 211
R ++ GTG +D + KGA GK +
Sbjct: 68 ----RMVSKSKDGTGSDDKKA-----------------------KGADGKTKIATPRGAA 100
Query: 212 -PGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA-------EG 263
PG K + + R P +PP+ +P G PP++ R S PG P
Sbjct: 101 PPGQKGQANATR-----IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 155
Query: 264 AIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPL 299
++P P K + + P PS +++ Q AP+
Sbjct: 156 SLPTPPTREPK-KVAVVRTPPKSPSSAKSRLQTAPV 190
>gi|87578255 microtubule-associated protein 2 isoform 4 [Homo
sapiens]
Length = 502
Score = 332 bits (851), Expect = 8e-91
Identities = 191/406 (47%), Positives = 251/406 (61%), Gaps = 46/406 (11%)
Query: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGA-- 454
T + LK +H ++ PL + + P PP SP +VT + G
Sbjct: 99 TAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESA 158
Query: 455 ------KEMKLKGADGKTKIATPRGAAP------PGQKG----------------QANAT 486
K+ K K +DG TK R + P P ++G ++A
Sbjct: 159 LAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 218
Query: 487 RIPAKTP---------PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPT 537
R P P TP S+ P + +PG+PGTP S RTP P P
Sbjct: 219 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPRTPHTPGTPK 277
Query: 538 R-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKV 592
KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG+V
Sbjct: 278 SAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV 336
Query: 593 QIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 652
+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+PGGG
Sbjct: 337 RILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGG 396
Query: 653 QVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 712
+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +
Sbjct: 397 RVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQ 456
Query: 713 SPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 457 SPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 502
>gi|87578394 microtubule-associated protein 2 isoform 5 [Homo
sapiens]
Length = 559
Score = 328 bits (841), Expect = 1e-89
Identities = 204/466 (43%), Positives = 269/466 (57%), Gaps = 64/466 (13%)
Query: 343 GEDTKEADLPEPSEKQPAAAPR--GKPVSRVPQLKARMVSKSKDGTGSDDKKA-----KT 395
GE KEA + + P AA P S P + ++ G + A +
Sbjct: 108 GEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESALAPSVFKQA 167
Query: 396 STRSSAKTLKNRPCL--SPKHPTPGSSDP------------LIQPSSPAVCPEPPSSPKH 441
+ S TL P L S K P S+ P LIQP+S P S
Sbjct: 168 KDKVSNSTLSKIPALQGSTKSPRYSSACPSTTKRATFSDSLLIQPTSAGSTDRLPYS--- 224
Query: 442 VSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPP--GQKGQ------------ANATR 487
SG K+ K + ++ + P PP G G +++ R
Sbjct: 225 ---------KSGNKDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 275
Query: 488 IPAKTPP----------APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPT 537
++ P P TP S+ P + +PG+PGTP S RTP P P
Sbjct: 276 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPRTPHTPGTPK 334
Query: 538 R-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKV 592
KKVA++RTPPKSP++ K +L+ P+PDLKNVKSKIGST+N+K+QP GG+V
Sbjct: 335 SAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLKNVKSKIGSTDNIKYQPKGGQV 393
Query: 593 QIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 652
+I+NKK+D S VQS+CGSKDNIKH GGG+VQIV K +DLS VTSKCGSL NI H+PGGG
Sbjct: 394 RILNKKIDFSKVQSRCGSKDNIKHSAGGGNVQIVTKKIDLSHVTSKCGSLKNIRHRPGGG 453
Query: 653 QVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 712
+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +
Sbjct: 454 RVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQ 513
Query: 713 SPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 514 SPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 559
>gi|87578392 microtubule-associated protein 2 isoform 2 [Homo
sapiens]
Length = 471
Score = 262 bits (669), Expect = 1e-69
Identities = 167/406 (41%), Positives = 220/406 (54%), Gaps = 77/406 (18%)
Query: 397 TRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGA-- 454
T + LK +H ++ PL + + P PP SP +VT + G
Sbjct: 99 TAEAVAVLKGEQEKEAQHKDQTAALPLAAEETANLPPSPPPSPASEQTVTVEEAAGGESA 158
Query: 455 ------KEMKLKGADGKTKIATPRGAAP------PGQKG----------------QANAT 486
K+ K K +DG TK R + P P ++G ++A
Sbjct: 159 LAPSVFKQAKDKVSDGVTKSPEKRSSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSAR 218
Query: 487 RIPAKTP---------PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPT 537
R P P TP S+ P + +PG+PGTP S RTP P P
Sbjct: 219 RTTRSEPIRRAGKSGTSTPTTPGSTAITPGTPPSYSSRTPGTPGTP-SYPRTPHTPGTPK 277
Query: 538 R-----EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKV 592
KKVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 278 SAILVPSEKKVAIIRTPPKSPATPK-QLRLINQPLPDLK--------------------- 315
Query: 593 QIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGG 652
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H+PGGG
Sbjct: 316 ----------NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGG 365
Query: 653 QVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYK 712
+V+++S KLDFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +
Sbjct: 366 RVKIESVKLDFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQ 425
Query: 713 SPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
SP S SPR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 426 SPGRSSVASPRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 471
>gi|87578396 microtubule-associated protein 2 isoform 1 [Homo sapiens]
Length = 1827
Score = 259 bits (661), Expect = 8e-69
Identities = 206/577 (35%), Positives = 280/577 (48%), Gaps = 96/577 (16%)
Query: 209 KERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLP 268
+ RP +E E+ +V+E++ + P SP P + RE ++ + E
Sbjct: 1320 ERRPSPHDE--EEFEVEEAAEAQAEPKDGSP----EAPASPEREEVALSEYKTETYDDY- 1372
Query: 269 VDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFP 328
K T I S D S+ D T +E P +K +E+ R++
Sbjct: 1373 -----KDETTIDDSIMDADSLWVDTQDDDRSIMTEQLETIPKEEK----AEKEARRSSLE 1423
Query: 329 GAPGEGPEARGPS-LGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTG 387
E P G + ++ EPS R K V + KA + K++
Sbjct: 1424 KHRKEKPFKTGRGRISTPERKVAKKEPSTVSRDEVRRKKAVYK----KAELAKKTEVQAH 1479
Query: 388 SDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS---------SPAVCPEPP-- 436
S +K + C+ K G L PS S V P
Sbjct: 1480 SPSRKFILKPAIKYTRPTHLSCVKRKTTAAGGESALA-PSVFKQAKDKVSDGVTKSPEKR 1538
Query: 437 -SSPKHVSSVTSRTGSSGAKE-------MKLKGADGKTKIATPRGAAPPGQKGQANATRI 488
S P+ S + R G SG ++ + + +T + P A G+ G + T
Sbjct: 1539 SSLPRPSSILPPRRGVSGDRDENSFSLNSSISSSARRTTRSEPIRRA--GKSGTSTPTT- 1595
Query: 489 PAKTPPAPKTPPSSGEPPKSGDRSGYSS--PGSPGTPGSRSRTPSLPTPPTR-----EPK 541
P T P TPPS YSS PG+PGTP S RTP P P K
Sbjct: 1596 PGSTAITPGTPPS------------YSSRTPGTPGTP-SYPRTPHTPGTPKSAILVPSEK 1642
Query: 542 KVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDL 601
KVA++RTPPKSP++ K +L+ P+PDLK
Sbjct: 1643 KVAIIRTPPKSPATPK-QLRLINQPLPDLK------------------------------ 1671
Query: 602 SNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKL 661
NV+SK GS DNIK+ P GG VQIV K +DLS VTSKCGSL NI H+PGGG+V+++S KL
Sbjct: 1672 -NVKSKIGSTDNIKYQPKGGQVQIVTKKIDLSHVTSKCGSLKNIRHRPGGGRVKIESVKL 1730
Query: 662 DFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAKTDHGAEIVYKSPVVSGDTS 721
DFK++ Q+K+GSLDN HVPGGGN KI++ KL FRE+AKA+ DHGAEI+ +SP S S
Sbjct: 1731 DFKEKAQAKVGSLDNAHHVPGGGNVKIDSQKLNFREHAKARVDHGAEIITQSPGRSSVAS 1790
Query: 722 PRHLSNVSSTGSIDMVDSPQLATLADEVSASLAKQGL 758
PR LSNVSS+GSI++++SPQLATLA++V+A+LAKQGL
Sbjct: 1791 PRRLSNVSSSGSINLLESPQLATLAEDVTAALAKQGL 1827
>gi|197276600 microtubule-associated protein 4 isoform 4 [Homo
sapiens]
Length = 1135
Score = 244 bits (624), Expect = 2e-64
Identities = 190/556 (34%), Positives = 248/556 (44%), Gaps = 100/556 (17%)
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
A +P A P+P+ + T+ SE + GQ A F E
Sbjct: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
Query: 313 K------EQAHSEEHLG-RAAFPGAPGE---------GPEARGPSLGEDTKEADLPEPSE 356
K E+ E LG R P E PE P + + P E
Sbjct: 633 KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR-----PCLS 411
P+ + KP++ K T + A T+ K + P
Sbjct: 693 LPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP 752
Query: 412 PKHPTPGSSDPLIQPS--------SPAVCPEPPSSP-KHVSSVTSRTGSSGAKEMKLKGA 462
PK P S+ P I PS + A PE +SP K S+ SR+GS + +
Sbjct: 753 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV----- 807
Query: 463 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 519
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 808 ---AKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
Query: 520 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 560
T + T T P V TP K P+SAK SRL
Sbjct: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
Query: 561 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 590
T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
Query: 591 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS
Sbjct: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
Query: 643 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFRENAKAK 702
NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG KIET++LTFR NA+A+
Sbjct: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKIETYRLTFRANARAR 1102
Query: 703 TDHGAEIVYKSPVVSG 718
TDHGA+IV + P G
Sbjct: 1103 TDHGADIVSRPPHFPG 1118
>gi|47519639 microtubule-associated protein 4 isoform 1 [Homo sapiens]
Length = 1152
Score = 207 bits (527), Expect = 3e-53
Identities = 172/527 (32%), Positives = 224/527 (42%), Gaps = 100/527 (18%)
Query: 253 ATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
A +P A P+P+ + T+ SE + GQ A F E
Sbjct: 573 AKDVPPLSETEATPVPIKDMEIAQTQKGISEDSHLESLQDVGQSAAPTFMISPETVTGTG 632
Query: 313 K------EQAHSEEHLG-RAAFPGAPGE---------GPEARGPSLGEDTKEADLPEPSE 356
K E+ E LG R P E PE P + + P E
Sbjct: 633 KKCSLPAEEDSVLEKLGERKPCNSQPSELSSETSGIARPEEGRPVVSGTGNDITTPPNKE 692
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR-----PCLS 411
P+ + KP++ K T + A T+ K + P
Sbjct: 693 LPPSPEKKTKPLATTQPAKTSTSKAKTQPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAP 752
Query: 412 PKHPTPGSSDPLIQPS--------SPAVCPEPPSSP-KHVSSVTSRTGSSGAKEMKLKGA 462
PK P S+ P I PS + A PE +SP K S+ SR+GS + +
Sbjct: 753 PKRPAVASARPSILPSKDVKPKPIADAKAPEKRASPSKPASAPASRSGSKSTQTV----- 807
Query: 463 DGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS---GYSSPGS 519
K T A G ++ +T +P K P A KT E K +S S P S
Sbjct: 808 ---AKTTTAAAVASTGPSSRSPSTLLPKK-PTAIKTEGKPAEVKKMTAKSVPADLSRPKS 863
Query: 520 PGTPGSRSRTPSLPTPPTREPKKVAVVRTP-----------PKSPSSAK--------SRL 560
T + T T P V TP K P+SAK SRL
Sbjct: 864 TSTSSMKKTTTLSGTAPAAGVVPSRVKATPMPSRPSTTPFIDKKPTSAKPSSTTPRLSRL 923
Query: 561 QTAPVPMPDLKNVKSKIGSTENLKHQPGGG------------------------------ 590
T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 924 ATN-TSAPDLKNVRSKVGSTENIKHQPGGGRAKVEKKTEAAATTRKPESNAVTKTAGPIA 982
Query: 591 --------KVQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSL 642
KVQI++KK+ S++QSKCGSKDNIKHVPGGG+VQI K VD+SKV+SKCGS
Sbjct: 983 SAQKQPAGKVQIVSKKVSYSHIQSKCGSKDNIKHVPGGGNVQIQNKKVDISKVSSKCGSK 1042
Query: 643 GNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIE 689
NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+P GG K E
Sbjct: 1043 ANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPAGGAVKTE 1089
>gi|47519675 microtubule-associated protein 4 isoform 2 [Homo
sapiens]
Length = 887
Score = 206 bits (524), Expect = 6e-53
Identities = 155/437 (35%), Positives = 200/437 (45%), Gaps = 105/437 (24%)
Query: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406
K A + P E +P + G ++ P + + K + + AKTST S AKT
Sbjct: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKTQPT 457
Query: 407 R-------------------------PCLSPKHPTPGSSDPLIQPS--------SPAVCP 433
P PK P S+ P I PS + A P
Sbjct: 458 SLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADAKAP 517
Query: 434 EPPSSP-KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492
E +SP K S+ SR+GS + + K T A G ++ +T +P K
Sbjct: 518 EKRASPSKPASAPASRSGSKSTQTV--------AKTTTAAAVASTGPSSRSPSTLLPKK- 568
Query: 493 PPAPKTPPSSGEPPKSGDRS---GYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP 549
P A KT E K +S S P S T + T T P V TP
Sbjct: 569 PTAIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATP 628
Query: 550 -----------PKSPSSAK--------SRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 590
K P+SAK SRL T PDLKNV+SK+GSTEN+KHQPGGG
Sbjct: 629 MPSRPSTTPFIDKKPTSAKPSSTTPRLSRLATN-TSAPDLKNVRSKVGSTENIKHQPGGG 687
Query: 591 --------------------------------------KVQIINKKLDLSNVQSKCGSKD 612
KVQI++KK+ S++QSKCGSKD
Sbjct: 688 RAKVEKKTEAAATTRKPESNAVTKTAGPIASAQKQPAGKVQIVSKKVSYSHIQSKCGSKD 747
Query: 613 NIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIG 672
NIKHVPGGG+VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+G
Sbjct: 748 NIKHVPGGGNVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVG 807
Query: 673 SLDNITHVPGGGNKKIE 689
SLDN+ H+P GG K E
Sbjct: 808 SLDNVGHLPAGGAVKTE 824
>gi|197276602 microtubule-associated protein 4 isoform 5 [Homo
sapiens]
Length = 817
Score = 162 bits (410), Expect = 1e-39
Identities = 125/369 (33%), Positives = 172/369 (46%), Gaps = 38/369 (10%)
Query: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406
K A + P E +P + G ++ P + + K + + AKTST S AKT
Sbjct: 399 KSAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTST-SKAKT--- 454
Query: 407 RPCLSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGA 462
+P PK P P G + + +S V PP P S+ S S K + A
Sbjct: 455 QPTSLPKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSKDVKPKPIADA 514
Query: 463 DGKTKIATP-RGAAPPGQKGQANATRIPAKTPPAP---KTPPSSGEP----PKS------ 508
K A+P + A+ P + + +T+ AKT A T PSS P PK
Sbjct: 515 KAPEKRASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPTAIKT 574
Query: 509 -GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 567
G + + P SR S T KK + + SR++ P+P
Sbjct: 575 EGKPAEVKKMTAKSVPADLSRPKSTSTSSM---KKTTTLSGTAPAAGVVPSRVKATPMPS 631
Query: 568 P-------DLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSKCGSKDNIKHVPGG 620
D K +K ST P ++ DL NV+SK GS +NIKH PGG
Sbjct: 632 RPSTTPFIDKKPTSAKPSSTT-----PRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGG 686
Query: 621 GSVQIVYKPVDLSKVTSKCGSLGNIHHKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHV 680
G VQI K VD+SKV+SKCGS NI HKPGGG V+++S+KL+FK++ Q+K+GSLDN+ H+
Sbjct: 687 GRVQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHL 746
Query: 681 PGGGNKKIE 689
P GG K E
Sbjct: 747 PAGGAVKTE 755
Score = 54.7 bits (130), Expect = 3e-07
Identities = 85/400 (21%), Positives = 143/400 (35%), Gaps = 60/400 (15%)
Query: 206 AGGKERPGSKEEVDEDRDVDESSPQD-----SPPSKASPAQDGRPPQTAAREA----TSI 256
+ G RP V D ++P + SP K P +P +T+ +A TS+
Sbjct: 400 SAGIARPEEGRPVVSGTGNDITTPPNKELPPSPEKKTKPLATTQPAKTSTSKAKTQPTSL 459
Query: 257 PGFPAEGAIP-LPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQ 315
P PA I L +S S +PA+ P P+V A+ P + ++ P +
Sbjct: 460 PKQPAPTTIGGLNKKPMSLASGLVPAAPPKRPAVASARPSILPSK-----DVKPKPIADA 514
Query: 316 AHSEEHLGRAAFPGAPGEGPEARGPS-----LGEDTKEADLPE--PSEKQPAAAPRGKPV 368
E+ A P P P +R S + + T A + PS + P+ KP
Sbjct: 515 KAPEKR----ASPSKPASAPASRSGSKSTQTVAKTTTAAAVASTGPSSRSPSTLLPKKPT 570
Query: 369 SRVPQLKA----RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424
+ + K +M +KS S K TS+ TL + P+ + P+
Sbjct: 571 AIKTEGKPAEVKKMTAKSVPADLSRPKSTSTSSMKKTTTLSGTAPAAGVVPSRVKATPM- 629
Query: 425 QPSSPAVCP---------EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAA 475
PS P+ P +P S+ +S + + T + K ++ K + P G
Sbjct: 630 -PSRPSTTPFIDKKPTSAKPSSTTPRLSRLATNTSAPDLKNVRSKVGSTENIKHQPGGGR 688
Query: 476 PPGQKGQANATRIPAKTPPAP--KTPPSSGEPPKSGDRSGYSSP---------------- 517
Q + + +++ +K K P G+ + +
Sbjct: 689 VQIQNKKVDISKVSSKCGSKANIKHKPGGGDVKIESQKLNFKEKAQAKVGSLDNVGHLPA 748
Query: 518 -GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 556
G+ T G S P P PP E ++ +P+SA
Sbjct: 749 GGAVKTEGGGSEAPLCPGPPAGEEPAISEAAPEAGAPTSA 788
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 96.3 bits (238), Expect = 9e-20
Identities = 146/570 (25%), Positives = 184/570 (32%), Gaps = 63/570 (11%)
Query: 33 QDQEGDTDAGLKESPLQTPTEDGSE--EPGSETSDAKSTPTAEDVTAPLVDEG----APG 86
+D T + SP PT P T K TPT V P EG AP
Sbjct: 847 KDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPK 906
Query: 87 KQAAAQPHTEIPEGTTAEEA--GIGDTPSLEDEAAGHVTQEPE-SGKVVQEGFLREPGPP 143
+ A + P+ A A GI +PS + P G P PP
Sbjct: 907 QAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 144 GLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPL 203
+ G P P P+ A P+ T P +GG P +G P
Sbjct: 967 AATPPSPKGGPATP----SPKGAPTPPAAT-PPSPKGGPATPS-----------PKGAPT 1010
Query: 204 KGAGGKERPGSKEEVDEDRDVDESSPQDSPPS-KASPAQDGRPPQTAAREATSIPGFPAE 262
A P + P +PPS K SPA P A ++P P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPS-PKG 1069
Query: 263 GAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHL 322
G + P S GP+ KG P TP K + H
Sbjct: 1070 GPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMP------PAATPPSPKGGLATPPHK 1123
Query: 323 GRAAFPGAPGEGPE---ARGPSLGEDTKEADLPEPSEKQPAAAPRGK-----PVSRVPQL 374
G P A P+ A P G T A P PS K A P K P + P
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATP-PSPKGGLATPPPKGAPTTPAATPPSP 1182
Query: 375 KARMVSKSKDGTGSDDKKAKTSTRS-----SAKTLKNRPCLSPKHPTPGSSDPLIQ--PS 427
K + + S G + S + S K P +P P G + P + P+
Sbjct: 1183 KGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPT 1242
Query: 428 SPAVCPEPPSS------PKHVSSVTSRTGSS---GAKEMKLKGADGKTKIATPRGAAPPG 478
+PA P P PK + + T S G KGA + P P
Sbjct: 1243 TPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPA 1302
Query: 479 QKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSP-GTPGSRSRTPSLPTPPT 537
A PA TPP+PK P + PPK +P SP GTP + TPS PT
Sbjct: 1303 TSPPKGAPTPPAATPPSPKGSPGT-PPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 538 REPKKVAVVRTPP-KSPSSAKSRLQTAPVP 566
K TPP +PS T P P
Sbjct: 1362 TPSSKEG--PTPPAATPSHKGGPAMTPPSP 1389
Score = 84.3 bits (207), Expect = 4e-16
Identities = 149/614 (24%), Positives = 200/614 (32%), Gaps = 118/614 (19%)
Query: 46 SPLQTPTEDGSEEP----GSETSDAKSTPTAEDVTAPL---------VDEGAPGKQAAAQ 92
SP PT + P G T K PT VT P +GA AA
Sbjct: 981 SPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKGSPAATPFPKGASTPPAATP 1040
Query: 93 PHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG 152
P + T G TP+ T G P PP + G
Sbjct: 1041 PSPKGSPAATPLPKGAPTTPA--------ATLPSPKGGPATPSLKGAPTPPAATPPSPKG 1092
Query: 153 MPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERP 212
P P P+ A P+ T P +GG P H+ PP GG P
Sbjct: 1093 GPATP----SPKGAPMPPAAT-PPSPKGGLATPP---HKGAPTTPAATPP-SPKGGLATP 1143
Query: 213 GSKEEVDEDRDVDESSPQDSPPSK----ASPAQDGRPPQTAAREATSIPGFPAEG-AIPL 267
K ++P +PPS A+P G P AA P P G A P
Sbjct: 1144 PPKGA--------PTTPAATPPSPKGGLATPPPKGAPTTPAAT-----PPSPKGGLATPS 1190
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAF 327
P K + PA+ P P G A TP+ + AA
Sbjct: 1191 P-----KGAPTTPAATPPSPKGGLA---------------TPSPKGAPTTP------AAT 1224
Query: 328 PGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPV---SRVPQLKARMVSKSKD 384
P +P G P T A P P P+G P + P LK + +
Sbjct: 1225 PPSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK 1284
Query: 385 GTGSDDKKAKTSTR-----SSAKTLKNRPCLSPKHP--TPGSSDPLIQPSSPAVCPEPP- 436
G + S + S K P +P P +PG+ P P+ PAV P P
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPK 1344
Query: 437 -------SSPKHVSSVTSRTGSSG----AKEMKLKGADGKTKIATPRGAAPPGQKGQANA 485
++P T+ + G A KG T + RG A P KG +
Sbjct: 1345 GTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTS 1404
Query: 486 TRI----PAKTPPAPKT-----PPSSGE--PPKSGDRSGYSSP------GSPGTPGSRSR 528
+ P K P P T PS G+ PP S +P G P TP S+
Sbjct: 1405 PAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKG- 1463
Query: 529 TPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNV----KSKIGSTENLK 584
P+LP PK+ + S S K+ AP+ P L V ++ +T + +
Sbjct: 1464 DPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPSSR 1523
Query: 585 HQPGGGKVQIINKK 598
P +++KK
Sbjct: 1524 RDPIAPTATLLSKK 1537
Score = 84.0 bits (206), Expect = 5e-16
Identities = 151/577 (26%), Positives = 198/577 (34%), Gaps = 111/577 (19%)
Query: 44 KESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTA 103
K SP TP G+ P + T + P PL +GAP AA P P+G A
Sbjct: 1020 KGSPAATPFPKGASTPPAATPPS---PKGSPAATPL-PKGAPTTPAATLPS---PKGGPA 1072
Query: 104 EEAGIGDTPSLEDEAAGHVTQEPE-SGKVVQEGFLREPGPPGLSHQLMSG------MPGA 156
TPSL+ P G P PP + G GA
Sbjct: 1073 -------TPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA 1125
Query: 157 PLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGA---------- 206
P P + + T P +G P G L PP KGA
Sbjct: 1126 PTTPAATPPSPKGGLATPPP--KGAPTTPAATPPSPKGGLAT--PPPKGAPTTPAATPPS 1181
Query: 207 --GGKERPGSKEEVDEDRDVDESSPQDSPPSK----ASPAQDGRPPQTAAREATSIPGFP 260
GG P K ++P +PPS A+P+ G P AA P P
Sbjct: 1182 PKGGLATPSPKGA--------PTTPAATPPSPKGGLATPSPKGAPTTPAAT-----PPSP 1228
Query: 261 AEG-AIPLPVDFLSKVSTEIPASEPDGPSVGRA----KGQDAPLEFTFHVEITPNVQKEQ 315
G A P P K + PA+ P P G A KG P TP K
Sbjct: 1229 KGGLATPSP-----KGAPTTPAATPPSPKGGPATPPPKGAPTP------PAATPPSLKGG 1277
Query: 316 AHSEEHLGR----AAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPV--- 368
+ H G P +P GP P A P P P+G P
Sbjct: 1278 LATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPA 1337
Query: 369 ------SRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS-- 420
P L A S SK G + K + ++ + K P ++P P G +
Sbjct: 1338 VTPPSPKGTPTLPATTPS-SKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIP 1396
Query: 421 DPLIQPSSPAVCP----EPPSSPKHVSSVTSRTGSSG------AKEMKLKGADGKTKIAT 470
P P+SPAV P + P++P V+ + T S G + LK A + A
Sbjct: 1397 SPKGDPTSPAVIPLSPKKAPATP--VTREGAATPSKGDLTPPAVTPVSLKKAPATS--AP 1452
Query: 471 PRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP-GSPGTPGSRSRT 529
G A P KG +PA TPP+PK EPP + SSP +P TP
Sbjct: 1453 KGGPATPSSKGDPT---LPAVTPPSPK------EPPAPKQVATSSSPKKAPATPAPMG-A 1502
Query: 530 PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVP 566
P+LP PK+V + + P + + L + P
Sbjct: 1503 PTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTP 1539
Score = 76.3 bits (186), Expect = 1e-13
Identities = 133/587 (22%), Positives = 190/587 (32%), Gaps = 109/587 (18%)
Query: 38 DTDAGLKESPLQTPTE-----DGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQ 92
D+ L +S L TPT + ++ G + AK T T +P ++ G + A
Sbjct: 630 DSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLE----GTVSLAP 685
Query: 93 PHTEIPEGT---------TAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPP 143
+ + EGT +E + +P + PE K V L G P
Sbjct: 686 KNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP 745
Query: 144 GLSHQLMSGMPGAPLLP--EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLG----DLH 197
+ ++ + L P P+E + SG + G LG
Sbjct: 746 PGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPSPLGVSVSPQT 805
Query: 198 QEGPPLKGAGGKERP------------------------GSKEEVDEDRDVDESSPQDSP 233
+ P KG+ G + P GSK+ SP+ +P
Sbjct: 806 KRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAP 865
Query: 234 -PSKASPAQDGR----PPQTAAREATSIPGFPAEG-AIPLPVDFLSKVSTEIPASEPDGP 287
PS +P P +T ++P FP EG A P P + PA
Sbjct: 866 TPSAVTPLSPKGVTLPPKETPTPSVVNLP-FPKEGPATPAP--------KQAPALSMTSS 916
Query: 288 SVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTK 347
S +A+ AP + + AA P +P GP P
Sbjct: 917 SPKKARATPAP----------KGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPP 966
Query: 348 EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNR 407
A P P +P+G P P K T S K A T + + K
Sbjct: 967 AATPPSPKGGPATPSPKGAPT---PPAATPPSPKGGPATPSP-KGAPTPPAVTPPSPKGS 1022
Query: 408 PCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTK 467
P +P P S+ P P SP P PK + + T
Sbjct: 1023 PAATP-FPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAAT------------------ 1063
Query: 468 IATPRGA-APPGQKGQANATRIPAKTPPAPK----TPPSSGEP-----PKSGDRSGYSSP 517
+ +P+G A P KG A PA TPP+PK TP G P + G ++P
Sbjct: 1064 LPSPKGGPATPSLKG---APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATP 1120
Query: 518 GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 564
G P + + TP P P TP +P S K L T P
Sbjct: 1121 PHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPP 1167
Score = 73.2 bits (178), Expect = 9e-13
Identities = 150/595 (25%), Positives = 205/595 (34%), Gaps = 98/595 (16%)
Query: 42 GLKESPLQTPT--EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTE 96
G +P TP + G P G+ T+ A + P+ + A +GAP AA P
Sbjct: 1124 GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPS-- 1181
Query: 97 IPEG--TTAEEAGIGDTPSLEDEA--AGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG 152
P+G T G TP+ + G T P+ PP L +
Sbjct: 1182 -PKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT-----PPSPKGGLATP 1235
Query: 153 MP-GAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKE- 210
P GAP P + + T P +G P L G L PP KGA
Sbjct: 1236 SPKGAPTTPAATPPSPKGGPATPPP--KGAPTPPAATPPSLKGGLAT--PPHKGAPNPAV 1291
Query: 211 -RPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIP-GFPAEGAIPLP 268
P S + P SPP A PP T P G P A+ P
Sbjct: 1292 VTPPSPK----------GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPP 1341
Query: 269 VDFLSKVSTEIPASEPD---GPSVGRAK-GQDAPLEFTFHV---EITPNVQKE----QAH 317
K + +PA+ P GP+ +K G P H +TP K +
Sbjct: 1342 SP---KGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSP 1398
Query: 318 SEEHLGRAAFPGAPGEGPE-------ARGPSLGEDTKEADLPEPSEKQPA-AAPRGKPVS 369
+ A P +P + P A PS G+ T A P +K PA +AP+G P +
Sbjct: 1399 KGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPAT 1458
Query: 370 RV----PQLKARMVSKSKD-------GTGSDDKKAK-TSTRSSAKTLKNRPCLSPKHP-- 415
P L A K+ T S KKA T A TL P + P P
Sbjct: 1459 PSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL---PAVIPSSPKE 1515
Query: 416 ---TPGSSDPLIQPSSPAVCPEPPSS--PKHVSSVTSRTGSSGAKEMKLK------GADG 464
TP S I P++ + + P++ PK + T S K +
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575
Query: 465 KTKIATPRGAAPPGQKGQANATRI---PAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 521
+ ++P P KG + + PA T P+PK P+ G ++P G
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Query: 522 TPGSRSRTPS----LPTPPTREPKKV------AVVRTPPKSPSSAKSRLQTAPVP 566
TP S TPS PT P K+ A P K +A + AP P
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAP 1690
Score = 72.8 bits (177), Expect = 1e-12
Identities = 153/613 (24%), Positives = 215/613 (35%), Gaps = 110/613 (17%)
Query: 42 GLKESPLQTPT--EDGSEEP---GSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPH-- 94
G +P TP + G P G+ T+ A + P+ + A +GAP AA P
Sbjct: 1193 GAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPK 1252
Query: 95 ----TEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLM 150
T P+G A PSL+ G + P G + P P G
Sbjct: 1253 GGPATPPPKGAPTPPAAT--PPSLK----GGLATPPHKG-APNPAVVTPPSPKG--GPAT 1303
Query: 151 SGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKE 210
S GAP P + + GT P +G P + G GG
Sbjct: 1304 SPPKGAPTPPAATPPSPKGSPGTPPP--KGAPTPPAVTPPSPKGTPTLPATTPSSKGGPT 1361
Query: 211 RPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIP-GFPAEGAIPLPV 269
P SKE + P +P K PA PP A P G P A+ +P+
Sbjct: 1362 TPSSKE--------GPTPPAATPSHKGGPAMT--PPSPKRGPAIPSPKGDPTSPAV-IPL 1410
Query: 270 DFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPG 329
+T + PS G ++TP A + L +A
Sbjct: 1411 SPKKAPATPVTREGAATPSKG---------------DLTP-----PAVTPVSLKKAPATS 1450
Query: 330 APGEGPEARGPSLGEDTKEADLPEPSEKQPAA--------APRGKPVSRVPQ----LKAR 377
AP GP A S G+ T A P PS K+P A +P+ P + P L A
Sbjct: 1451 APKGGP-ATPSSKGDPTLPAVTP-PSPKEPPAPKQVATSSSPKKAPATPAPMGAPTLPAV 1508
Query: 378 MVSKSKDGTGSDDKK----AKTSTRSSAKT---LKNRPCLSPKHPTPGSSDPLIQPSSPA 430
+ S K+ + + A T+T S KT L + L P T S +P
Sbjct: 1509 IPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPK 1568
Query: 431 VCPEPPSSPKHVS--SVTSRT--GSSGAKEMKLKGA---DGKTKIATPRGAAPPGQKGQA 483
P PSS + S +VT T G+ KE+ + A + TP PP + +
Sbjct: 1569 EAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPE-KG 1627
Query: 484 NATRIPAKTPPAPKTPPSSGEPP---------KSGDRSGYSSPGSPGTPGSRS------- 527
AT P TP +P PSS + K G +S G P G +
Sbjct: 1628 PATPAPKGTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVA 1687
Query: 528 ----RTPSLPTPPTREP--KKVAVVRTP----PKSPSSAKSRLQT-APVPMPDLKNVKSK 576
TP + P + P KK + P P + + +K L T AP P+ ++ SK
Sbjct: 1688 PAPESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSK 1747
Query: 577 IGSTENLKHQPGG 589
++ H P G
Sbjct: 1748 TAKGKDASHSPKG 1760
Score = 67.0 bits (162), Expect = 6e-11
Identities = 137/574 (23%), Positives = 200/574 (34%), Gaps = 90/574 (15%)
Query: 26 QGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEE---PGSETSDAKSTPTAEDVTAPLVDE 82
+GG T +EG T P TP+ G P + A +P D T+P V
Sbjct: 1357 KGGPTTPSSKEGPTP------PAATPSHKGGPAMTPPSPKRGPAIPSPKG-DPTSPAVIP 1409
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLREP 140
+P K+A A P T EG G P++ + T P+ G
Sbjct: 1410 LSP-KKAPATPVTR--EGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSS----K 1462
Query: 141 GPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEG 200
G P L + P +P P P++ S T AP L
Sbjct: 1463 GDPTLP----AVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAPTL------------- 1505
Query: 201 PPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFP 260
P + + KE P + D +P + SK +PA P + A ++P
Sbjct: 1506 PAVIPSSPKEVPATPSSRR-----DPIAPTATLLSKKTPATLA-PKEALIPPAMTVPSPK 1559
Query: 261 AEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEE 320
AIP P + + S++ AS P + KG +P E +T KE
Sbjct: 1560 KTPAIPTPKEAPATPSSK-EASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPP- 1617
Query: 321 HLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAA--------------APRGK 366
A P +P +GP P G T P + P + A +G
Sbjct: 1618 ----AVTPPSPEKGPATPAPK-GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGL 1672
Query: 367 PVSRVPQ-LKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQ 425
P + P LK +V+ + + T TR +T K+ P P P + +
Sbjct: 1673 PAKKGPTALKEVLVAPAPESTPI----ITAPTRKGPQTKKSSATSPPICPDPSAKNGSKG 1728
Query: 426 PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP-------PG 478
P S V P P + SS T++ G + K A ++K +TP AA P
Sbjct: 1729 PLS-TVAPAPLLPVQKDSSKTAK-GKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPE 1786
Query: 479 QKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR 538
+ A P P AP P+ PPK P +PG +PS P P
Sbjct: 1787 SASVSAAPSPPVSLPLAPSPVPTL--PPKQ--------QFLPSSPGLVLESPSKPLAPAD 1836
Query: 539 EPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKN 572
E + + ++ P P S Q+ V MP K+
Sbjct: 1837 EDELLPLI---PPEPISGGVPFQSVLVNMPTPKS 1867
Score = 58.9 bits (141), Expect = 2e-08
Identities = 103/439 (23%), Positives = 155/439 (35%), Gaps = 67/439 (15%)
Query: 159 LPEGPREATRQPSGTGPEDTEGGRH----APELLKHQLLGDLHQEGPPLKGAGGKERPGS 214
LP P + P P++T APE+ K L G P PG+
Sbjct: 698 LPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTP---------PGT 748
Query: 215 KEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
K+ VD +P S P K P +D TA+ + T + A+ PL V +
Sbjct: 749 KK-VDGISHTSALAPVASSP-KECPTEDSGASATASSKGTLT--YLADSPSPLGVSVSPQ 804
Query: 275 VS---TEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAP 331
T+ ++ PD P +G +P+E +F E +F G+
Sbjct: 805 TKRPPTKKGSAGPDTP-IGNLSSPVSPVEASFLPE----------------NSLSFQGSK 847
Query: 332 GEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGK--PVSRVPQLKARMVSKSKDGTGSD 389
P+ P PS P + P+G P P + K+G +
Sbjct: 848 DSPATTHSPT---PPSPKGAPTPSAVTPLS-PKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 390 -DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
K+A + +S+ K R +PK P S P P+ PA P P S
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKG-IPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 449 TGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 508
A KG G A P KG A PA TPP+PK P++ P +
Sbjct: 963 PTPPAATPPSPKG-----------GPATPSPKG---APTPPAATPPSPKGGPATPSPKGA 1008
Query: 509 GDRSGYSSPGSPGTPGSR-----SRTPSLPTPPTRE--PKKVAVVRTPPKSPSSAKSRLQ 561
+ P G+P + + TP TPP+ + P + + P +P++ +
Sbjct: 1009 PTPPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPK 1068
Query: 562 TAPVPMPDLKNVKSKIGST 580
P P LK + +T
Sbjct: 1069 GGPA-TPSLKGAPTPPAAT 1086
Score = 36.6 bits (83), Expect = 0.089
Identities = 81/359 (22%), Positives = 125/359 (34%), Gaps = 48/359 (13%)
Query: 228 SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIP------- 280
+PQ P S A+ A P T A +P + LP+ + T +P
Sbjct: 52 APQQCPLSAANQASPFPSPSTIASTPLEVPFPQSSSGTALPLGTAPEAPTFLPNLIGPPI 111
Query: 281 -------ASEPDGPSVGRAKGQDAPLEFTFHVEITP-NVQKEQAHSEEHLGRAAFPGAPG 332
AS P++ APL V + P +VQK A L
Sbjct: 112 SPAALALASPMIAPTLKGTPSSSAPLAL---VALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Query: 333 EGP--EARGPSLGEDTKEADLPEPSEKQPAAAPRGKP-----VSRVPQLKARMVSKSKDG 385
G P + K PSE P P+G P VS VP ++ + G
Sbjct: 169 SGSVITLSAPIAPSEPKTNLNKVPSEVVP--NPKGTPSPPCIVSTVPYHCVTPMASIQSG 226
Query: 386 TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSP-AVCPEPPSSPKHVSS 444
S + T+T + A SP+ S LI P +P ++ + P SP S
Sbjct: 227 VASLPQTTPTTTLAIA---------SPQVKDTTISSVLISPQNPGSLSLKGPVSPPAALS 277
Query: 445 VTSRTGSSGAKEMKLKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSG 503
+++++ K G + G+ P + + ++ +T P+ +
Sbjct: 278 LSTQSLPVVTSSQKTAGPNTPPDFPISLGSHLAPLHQSSFGSVQLLGQTGPS-----ALS 332
Query: 504 EPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVA----VVRTPPKSPSSAKS 558
+P +SS G+ P RS P LP+ P VA V + K PS+ S
Sbjct: 333 DPTVKTISVDHSSTGA-SYPSQRSVIPPLPSRNEVVPATVAAFPVVAPSVDKGPSTISS 390
Score = 32.7 bits (73), Expect = 1.3
Identities = 54/209 (25%), Positives = 69/209 (33%), Gaps = 36/209 (17%)
Query: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTP 112
++GS+ P S + A P +D + + A GK A+ P +G A TP
Sbjct: 1723 KNGSKGPLSTVAPAPLLPVQKDSS-----KTAKGKDASHSP-----KGPLAPPESKASTP 1772
Query: 113 SLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP----LLPEGPREATR 168
L A V +PES V P PP S +P P LP P
Sbjct: 1773 -LTAAAFEKVLPKPESASVSAA-----PSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLE 1826
Query: 169 QPSGT-------------GPEDTEGGRHAPELLKHQLL---GDLHQEGPPLKGAGGKERP 212
PS PE GG +L + + P K K
Sbjct: 1827 SPSKPLAPADEDELLPLIPPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNK 1886
Query: 213 GSKEEVDEDRDVDESSPQDSPPSKASPAQ 241
GS E D D V E QDS + AQ
Sbjct: 1887 GSGTESDSDESVPELEEQDSTQATTQQAQ 1915
Score = 32.0 bits (71), Expect = 2.2
Identities = 50/194 (25%), Positives = 74/194 (38%), Gaps = 30/194 (15%)
Query: 395 TSTRSSAKTLKNRPCLSPKHPTPGSSDPL--IQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T + T + C+SP P SS P+ I+P+SPA P +PK S+ + T
Sbjct: 448 TIAAAPTTTFEVATCVSP----PMSSGPISNIEPTSPAALVMAPVAPKEPSTQVATTLRI 503
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSG--------- 503
D K ++ P Q + +PA AP +P +G
Sbjct: 504 PVSPPLPDPEDLKNLPSSVLVKFPT----QKDLQTVPASLEGAPFSPAQAGLTTKKDPTV 559
Query: 504 -----EPPKSGD--RSGYSSPGSPGTPGSRSRTPSLPTP-PTREPKKVAVVRTPPKSPSS 555
PK+ +S SSP P +P + SL P P +P A T P +S
Sbjct: 560 LPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLGEPLPIGKP---ASSMTSPLGVNS 616
Query: 556 AKSRLQTAPVPMPD 569
+ S ++T PD
Sbjct: 617 SASVIKTDSYAGPD 630
Score = 30.4 bits (67), Expect = 6.4
Identities = 22/88 (25%), Positives = 38/88 (43%), Gaps = 9/88 (10%)
Query: 481 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
G+A T +PA P+ + P S S ++ G PG P+LP P + P
Sbjct: 3 GEATET-VPATEQELPQPQAETAVLPMSSALSVTAALGQPG--------PTLPPPCSPAP 53
Query: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
++ + SP + S + + P+ +P
Sbjct: 54 QQCPLSAANQASPFPSPSTIASTPLEVP 81
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/557 (22%), Positives = 196/557 (35%), Gaps = 58/557 (10%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 214 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 273
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 274 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 329
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 330 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 378
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 379 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 432
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 433 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 488
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 489 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 546
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 547 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 604
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPAKTPPAPKTPPSSGEP- 505
+ +S + K TP+G AP K A T + PA T P P + EP
Sbjct: 605 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 656
Query: 506 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP- 564
P + + T G S T P P T PK+ A +P++ K T P
Sbjct: 657 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--PKETAPTTPKEPAPTTPKKPAPTTPE 714
Query: 565 VPMPDLKNVKSKIGSTE 581
P P V + + E
Sbjct: 715 TPPPTTSEVSTPTTTKE 731
Score = 69.3 bits (168), Expect = 1e-11
Identities = 136/596 (22%), Positives = 197/596 (33%), Gaps = 100/596 (16%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 319
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 320 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 368
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 369 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 423
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 424 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 483
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 484 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 540
Query: 329 GAPGEG--------------------PEARGPSLGEDTKEADLPEPSE------------ 356
P E P+ P+ + T L EP+
Sbjct: 541 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 600
Query: 357 ----KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
K+P + KP P+ A K T + T ++ TLK +P
Sbjct: 601 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 660
Query: 413 KHPTPGSSDPLIQ--PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
K P P P P+S P++PK + T + + + K T
Sbjct: 661 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--------KPAPTT 712
Query: 471 PRGAAP-PGQKGQANATRIPAKTPPAP--KTPPSSGEP-PKSGDRSGYSSPGSPGTPGSR 526
P P + T+ P +P TP S EP PK+ + +SP PG P ++
Sbjct: 713 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTK 768
Query: 527 SRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 580
+ + P T K +RT P++ ++A T K +SKI +T
Sbjct: 769 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITAT 822
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/347 (23%), Positives = 129/347 (37%), Gaps = 46/347 (13%)
Query: 214 SKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
+KE E ++ ++ Q S DG+ T+A+E SI A+ P S
Sbjct: 145 NKETTVETKETTTTNKQTST--------DGKEKTTSAKETQSIEKTSAKDLAPT-----S 191
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
KV + P + + + G A T E TP KE A + + P
Sbjct: 192 KVLAK-PTPKAETTTKGPA--------LTTPKEPTPTTPKEPASTTP---KEPTPTTIKS 239
Query: 334 GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKA 393
P TK A + K+PA +P P+ A +K T + K A
Sbjct: 240 APTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSA 294
Query: 394 KTSTRSSAKTLKNRPC-LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T+ + A T +P +PK P P + + +P EP + K + T + +
Sbjct: 295 PTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPTPTTPKEPAPTTKEPAPTTPKEPAP 350
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----PPSSGEPPKS 508
A + + TP+ AP K + T PAP T P ++ EP +
Sbjct: 351 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPT 406
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPT-REPKKVAVVRTPPKSPS 554
+S ++P P ++ P+ P P PKK A T PK P+
Sbjct: 407 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPA 451
Score = 57.8 bits (138), Expect = 4e-08
Identities = 126/586 (21%), Positives = 194/586 (33%), Gaps = 114/586 (19%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 470 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 522
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 523 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 558
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 559 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 608
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 609 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 665
Query: 283 EPDGPSVGR---AKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
+ P+ + + D P T E P KE A + P P P
Sbjct: 666 KELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTTPETPP--PTTSE 722
Query: 340 PSLGEDTKEADL----PEPSEKQPAAAPRGKPVSR------VPQLKARMVSKSKDGTGSD 389
S TKE P+ S + +A P K + VP K +K + T +
Sbjct: 723 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 782
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
DK + R++ +T P ++ + A E + K ++ T T
Sbjct: 783 DKTTERDLRTTPETTTAAPKMTKE---------------TATTTEKTTESKITATTTQVT 827
Query: 450 GSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG 509
++ K KT P+ T+ T P + +P
Sbjct: 828 STTTQDTTPFKITTLKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK--- 874
Query: 510 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQ 561
DR+ S++ TP P PT+ PKK + P PK+ + +
Sbjct: 875 DRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 923
Query: 562 TAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
T P P + ++ + +T P V++ K D + +
Sbjct: 924 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 969
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 16/176 (9%)
Query: 394 KTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPA-VCPEPPSS--PKHVSSVTSRTG 450
KTS + A T K +PK T L P P P+ P+S PK + T ++
Sbjct: 181 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 240
Query: 451 SSGAKEMKLKGADGKTKIA--TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 508
+ KE A TK A TP+ AP T+ PA T P P ++ EP +
Sbjct: 241 PTTPKEP----APTTTKSAPTTPKEPAP-------TTTKEPAPTTPKEPAPTTTKEPAPT 289
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 564
+S ++P P + P+ P P K TP + + K T P
Sbjct: 290 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 345
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/216 (26%), Positives = 86/216 (39%), Gaps = 33/216 (15%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSP-------AVCPEP 435
G+G D+ K +T ++ T N+ SPK T P + P + P+S V E
Sbjct: 89 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 148
Query: 436 PSSPKHVSSVTSRTGSSG------AKE-MKLKGADGKTKIATPRGAAPPGQKGQANATRI 488
K ++ +T + G AKE ++ K T + A P K + T+
Sbjct: 149 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE-TTTKG 207
Query: 489 PAKTPPAPKTP-----PSSGEPPKSGDRSGYSSPGSPGTPG-----SRSRTPSLPTPPTR 538
PA T P TP P+S P + + S+P +P P S TP P P T
Sbjct: 208 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 267
Query: 539 E------PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
+ PK+ A T +P++ KS T P P
Sbjct: 268 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 303
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 645 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 703
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 704 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 755
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 756 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 804
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 805 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 861
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 862 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 894
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/557 (22%), Positives = 196/557 (35%), Gaps = 58/557 (10%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 255 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 314
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 315 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 370
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 371 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 419
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 420 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 473
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 474 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 529
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 530 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 587
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 588 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 645
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPAKTPPAPKTPPSSGEP- 505
+ +S + K TP+G AP K A T + PA T P P + EP
Sbjct: 646 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 697
Query: 506 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP- 564
P + + T G S T P P T PK+ A +P++ K T P
Sbjct: 698 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--PKETAPTTPKEPAPTTPKKPAPTTPE 755
Query: 565 VPMPDLKNVKSKIGSTE 581
P P V + + E
Sbjct: 756 TPPPTTSEVSTPTTTKE 772
Score = 69.3 bits (168), Expect = 1e-11
Identities = 136/596 (22%), Positives = 197/596 (33%), Gaps = 100/596 (16%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 360
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 361 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 409
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 410 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 464
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 465 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 524
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 525 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 581
Query: 329 GAPGEG--------------------PEARGPSLGEDTKEADLPEPSE------------ 356
P E P+ P+ + T L EP+
Sbjct: 582 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 641
Query: 357 ----KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
K+P + KP P+ A K T + T ++ TLK +P
Sbjct: 642 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 701
Query: 413 KHPTPGSSDPLIQ--PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
K P P P P+S P++PK + T + + + K T
Sbjct: 702 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--------KPAPTT 753
Query: 471 PRGAAP-PGQKGQANATRIPAKTPPAP--KTPPSSGEP-PKSGDRSGYSSPGSPGTPGSR 526
P P + T+ P +P TP S EP PK+ + +SP PG P ++
Sbjct: 754 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTK 809
Query: 527 SRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 580
+ + P T K +RT P++ ++A T K +SKI +T
Sbjct: 810 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITAT 863
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/347 (23%), Positives = 129/347 (37%), Gaps = 46/347 (13%)
Query: 214 SKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
+KE E ++ ++ Q S DG+ T+A+E SI A+ P S
Sbjct: 186 NKETTVETKETTTTNKQTST--------DGKEKTTSAKETQSIEKTSAKDLAPT-----S 232
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
KV + P + + + G A T E TP KE A + + P
Sbjct: 233 KVLAK-PTPKAETTTKGPA--------LTTPKEPTPTTPKEPASTTP---KEPTPTTIKS 280
Query: 334 GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKA 393
P TK A + K+PA +P P+ A +K T + K A
Sbjct: 281 APTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSA 335
Query: 394 KTSTRSSAKTLKNRPC-LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T+ + A T +P +PK P P + + +P EP + K + T + +
Sbjct: 336 PTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPTPTTPKEPAPTTKEPAPTTPKEPAP 391
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----PPSSGEPPKS 508
A + + TP+ AP K + T PAP T P ++ EP +
Sbjct: 392 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPT 447
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPT-REPKKVAVVRTPPKSPS 554
+S ++P P ++ P+ P P PKK A T PK P+
Sbjct: 448 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPA 492
Score = 57.8 bits (138), Expect = 4e-08
Identities = 126/586 (21%), Positives = 194/586 (33%), Gaps = 114/586 (19%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 511 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 563
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 564 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 599
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 600 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 649
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 650 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 706
Query: 283 EPDGPSVGR---AKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
+ P+ + + D P T E P KE A + P P P
Sbjct: 707 KELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTTPETPP--PTTSE 763
Query: 340 PSLGEDTKEADL----PEPSEKQPAAAPRGKPVSR------VPQLKARMVSKSKDGTGSD 389
S TKE P+ S + +A P K + VP K +K + T +
Sbjct: 764 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 823
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
DK + R++ +T P ++ + A E + K ++ T T
Sbjct: 824 DKTTERDLRTTPETTTAAPKMTKE---------------TATTTEKTTESKITATTTQVT 868
Query: 450 GSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG 509
++ K KT P+ T+ T P + +P
Sbjct: 869 STTTQDTTPFKITTLKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK--- 915
Query: 510 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQ 561
DR+ S++ TP P PT+ PKK + P PK+ + +
Sbjct: 916 DRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 964
Query: 562 TAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
T P P + ++ + +T P V++ K D + +
Sbjct: 965 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1010
Score = 52.8 bits (125), Expect = 1e-06
Identities = 48/176 (27%), Positives = 68/176 (38%), Gaps = 16/176 (9%)
Query: 394 KTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPA-VCPEPPSS--PKHVSSVTSRTG 450
KTS + A T K +PK T L P P P+ P+S PK + T ++
Sbjct: 222 KTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSA 281
Query: 451 SSGAKEMKLKGADGKTKIA--TPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKS 508
+ KE A TK A TP+ AP T+ PA T P P ++ EP +
Sbjct: 282 PTTPKEP----APTTTKSAPTTPKEPAP-------TTTKEPAPTTPKEPAPTTTKEPAPT 330
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP 564
+S ++P P + P+ P P K TP + + K T P
Sbjct: 331 TTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTP 386
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/216 (26%), Positives = 86/216 (39%), Gaps = 33/216 (15%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSP-------AVCPEP 435
G+G D+ K +T ++ T N+ SPK T P + P + P+S V E
Sbjct: 130 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 189
Query: 436 PSSPKHVSSVTSRTGSSG------AKE-MKLKGADGKTKIATPRGAAPPGQKGQANATRI 488
K ++ +T + G AKE ++ K T + A P K + T+
Sbjct: 190 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE-TTTKG 248
Query: 489 PAKTPPAPKTP-----PSSGEPPKSGDRSGYSSPGSPGTPG-----SRSRTPSLPTPPTR 538
PA T P TP P+S P + + S+P +P P S TP P P T
Sbjct: 249 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 308
Query: 539 E------PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
+ PK+ A T +P++ KS T P P
Sbjct: 309 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 344
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 686 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 744
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 745 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 796
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 797 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 845
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 846 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 902
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 903 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 935
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/557 (22%), Positives = 196/557 (35%), Gaps = 58/557 (10%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 307 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 366
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 367 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 422
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 423 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 471
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 472 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 525
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 526 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 581
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 582 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 639
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 640 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 697
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPAKTPPAPKTPPSSGEP- 505
+ +S + K TP+G AP K A T + PA T P P + EP
Sbjct: 698 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 749
Query: 506 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP- 564
P + + T G S T P P T PK+ A +P++ K T P
Sbjct: 750 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--PKETAPTTPKEPAPTTPKKPAPTTPE 807
Query: 565 VPMPDLKNVKSKIGSTE 581
P P V + + E
Sbjct: 808 TPPPTTSEVSTPTTTKE 824
Score = 69.3 bits (168), Expect = 1e-11
Identities = 136/596 (22%), Positives = 197/596 (33%), Gaps = 100/596 (16%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 412
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 413 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 461
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 462 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 516
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 517 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 576
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 577 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 633
Query: 329 GAPGEG--------------------PEARGPSLGEDTKEADLPEPSE------------ 356
P E P+ P+ + T L EP+
Sbjct: 634 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 693
Query: 357 ----KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
K+P + KP P+ A K T + T ++ TLK +P
Sbjct: 694 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 753
Query: 413 KHPTPGSSDPLIQ--PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
K P P P P+S P++PK + T + + + K T
Sbjct: 754 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--------KPAPTT 805
Query: 471 PRGAAP-PGQKGQANATRIPAKTPPAP--KTPPSSGEP-PKSGDRSGYSSPGSPGTPGSR 526
P P + T+ P +P TP S EP PK+ + +SP PG P ++
Sbjct: 806 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTK 861
Query: 527 SRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 580
+ + P T K +RT P++ ++A T K +SKI +T
Sbjct: 862 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITAT 915
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/347 (23%), Positives = 129/347 (37%), Gaps = 46/347 (13%)
Query: 214 SKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
+KE E ++ ++ Q S DG+ T+A+E SI A+ P S
Sbjct: 238 NKETTVETKETTTTNKQTST--------DGKEKTTSAKETQSIEKTSAKDLAPT-----S 284
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
KV + P + + + G A T E TP KE A + + P
Sbjct: 285 KVLAK-PTPKAETTTKGPA--------LTTPKEPTPTTPKEPASTTP---KEPTPTTIKS 332
Query: 334 GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKA 393
P TK A + K+PA +P P+ A +K T + K A
Sbjct: 333 APTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSA 387
Query: 394 KTSTRSSAKTLKNRPC-LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T+ + A T +P +PK P P + + +P EP + K + T + +
Sbjct: 388 PTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPTPTTPKEPAPTTKEPAPTTPKEPAP 443
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----PPSSGEPPKS 508
A + + TP+ AP K + T PAP T P ++ EP +
Sbjct: 444 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPT 499
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPT-REPKKVAVVRTPPKSPS 554
+S ++P P ++ P+ P P PKK A T PK P+
Sbjct: 500 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPA 544
Score = 57.8 bits (138), Expect = 4e-08
Identities = 126/586 (21%), Positives = 194/586 (33%), Gaps = 114/586 (19%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 563 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 615
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 616 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 651
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 652 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 701
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 702 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 758
Query: 283 EPDGPSVGR---AKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
+ P+ + + D P T E P KE A + P P P
Sbjct: 759 KELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTTPETPP--PTTSE 815
Query: 340 PSLGEDTKEADL----PEPSEKQPAAAPRGKPVSR------VPQLKARMVSKSKDGTGSD 389
S TKE P+ S + +A P K + VP K +K + T +
Sbjct: 816 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 875
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
DK + R++ +T P ++ + A E + K ++ T T
Sbjct: 876 DKTTERDLRTTPETTTAAPKMTKE---------------TATTTEKTTESKITATTTQVT 920
Query: 450 GSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG 509
++ K KT P+ T+ T P + +P
Sbjct: 921 STTTQDTTPFKITTLKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK--- 967
Query: 510 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQ 561
DR+ S++ TP P PT+ PKK + P PK+ + +
Sbjct: 968 DRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1016
Query: 562 TAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
T P P + ++ + +T P V++ K D + +
Sbjct: 1017 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1062
Score = 53.5 bits (127), Expect = 7e-07
Identities = 82/363 (22%), Positives = 131/363 (36%), Gaps = 49/363 (13%)
Query: 216 EEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKV 275
EE+ E+ V E+ S S +S + R +++ A + E L V K
Sbjct: 111 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAAN-----RELQKKLKVKDNKKN 165
Query: 276 STEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA----FPGAP 331
T+ + P P V A +F T Q + + + A P P
Sbjct: 166 RTKKKPT-PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 224
Query: 332 GEGPEARGPSLG---EDTKEADLPEPSEKQPAAAPRGKPVSR-----VPQLKARMVSKSK 383
++ SL E T E + KQ + + K S + + A+ ++ +
Sbjct: 225 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 284
Query: 384 DGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVS 443
KA+T+T+ A T +PK PTP + P PA ++PK +
Sbjct: 285 KVLAKPTPKAETTTKGPALT-------TPKEPTPTT------PKEPA-----STTPKEPT 326
Query: 444 SVTSRTGSSGAKEMKLKGADGKTKIA--TPRGAAPPGQKGQANATRIPAKTPPAPKTPPS 501
T ++ + KE A TK A TP+ AP T+ PA T P P +
Sbjct: 327 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAP-------TTTKEPAPTTPKEPAPTT 375
Query: 502 SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQ 561
+ EP + +S ++P P + P+ P P K TP + + K
Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 562 TAP 564
T P
Sbjct: 436 TTP 438
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/216 (26%), Positives = 86/216 (39%), Gaps = 33/216 (15%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSP-------AVCPEP 435
G+G D+ K +T ++ T N+ SPK T P + P + P+S V E
Sbjct: 182 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 241
Query: 436 PSSPKHVSSVTSRTGSSG------AKE-MKLKGADGKTKIATPRGAAPPGQKGQANATRI 488
K ++ +T + G AKE ++ K T + A P K + T+
Sbjct: 242 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE-TTTKG 300
Query: 489 PAKTPPAPKTP-----PSSGEPPKSGDRSGYSSPGSPGTPG-----SRSRTPSLPTPPTR 538
PA T P TP P+S P + + S+P +P P S TP P P T
Sbjct: 301 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 360
Query: 539 E------PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
+ PK+ A T +P++ KS T P P
Sbjct: 361 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 396
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 738 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 796
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 797 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 848
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 849 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 897
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 898 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 954
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 955 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 987
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 78.2 bits (191), Expect = 3e-14
Identities = 126/557 (22%), Positives = 196/557 (35%), Gaps = 58/557 (10%)
Query: 44 KESPLQTPTEDGSEEPGSET-SDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHT-EIPEGT 101
KE TP E S P T + KS PT AP + AP P T + P T
Sbjct: 348 KEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPT 407
Query: 102 TAEEAGIGDTPSLEDEAAGHVTQE-PESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
T +E P+ E A T+ P + K ++P P + P
Sbjct: 408 TPKEPA----PTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTT 463
Query: 160 PEGPREATRQPSGTGPED---TEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKE 216
P+ P T++P+ T P++ T + AP K P + P + +
Sbjct: 464 PKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKE-----------PAPTTPKEPAPTTTK 512
Query: 217 EVDEDRDVDESSPQDSPPS--KASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSK 274
E ++P++ P+ K++P P T + A + P P+ P K
Sbjct: 513 EPSP------TTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPK 566
Query: 275 VSTEIPASEPDGPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFPGAPG 332
+P P+ + P E T + P KE A + + P P
Sbjct: 567 EPAPTTPKKP-APTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTP---KETAPTTPK 622
Query: 333 EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKK 392
+ L T E P E+ P +P P+ A K+ + +
Sbjct: 623 KLTPTTPEKLAPTTPEKPAPTTPEELAPTTPE-EPTPTTPEEPAPTTPKAA-APNTPKEP 680
Query: 393 AKTSTRSSAKTLKNRPC-LSPKHPTP----GSSDPLIQPSSPAVCPEPPSSPKHVSSVTS 447
A T+ + A T P +PK P G++ ++ +P +P +PK ++ T+
Sbjct: 681 APTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKP--APKELAPTTT 738
Query: 448 RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANAT-RIPAKTPPAPKTPPSSGEP- 505
+ +S + K TP+G AP K A T + PA T P P + EP
Sbjct: 739 KEPTSTTCD--------KPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPA 790
Query: 506 PKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAP- 564
P + + T G S T P P T PK+ A +P++ K T P
Sbjct: 791 PTTPKKPAPKELAPTTTKGPTSTTSDKPAPTT--PKETAPTTPKEPAPTTPKKPAPTTPE 848
Query: 565 VPMPDLKNVKSKIGSTE 581
P P V + + E
Sbjct: 849 TPPPTTSEVSTPTTTKE 865
Score = 69.3 bits (168), Expect = 1e-11
Identities = 136/596 (22%), Positives = 197/596 (33%), Gaps = 100/596 (16%)
Query: 44 KESPLQTPTEDG---SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
KE TP E ++EP T+ KS PT AP P K A P P
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTT--KSAPTTPKEPAPTT----PKKPAPTTPKEPAP-- 453
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQL-MSGMPGAPLL 159
TT +E TP+ E A T+EP +EP P + AP
Sbjct: 454 TTPKEP----TPTTPKEPAP-TTKEPAPTTP------KEPAPTAPKKPAPTTPKEPAPTT 502
Query: 160 PEGPREAT-RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
P+ P T ++PS T P++ AP K K A + S
Sbjct: 503 PKEPAPTTTKEPSPTTPKEP-----APTTTKSAPTTTKEPAPTTTKSAPTTPKEPSPTTT 557
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI------PGFPAEGAIPLPVDFL 272
E P + P K +P P T +E P P E A P +
Sbjct: 558 KEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETA 617
Query: 273 SKVSTEIPASEPD--GPSVGRAKGQDAPLEF--TFHVEITPNVQKEQAHSEEHLGRAAFP 328
++ + P+ P+ P E T E TP +E A + +AA P
Sbjct: 618 PTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTP---KAAAP 674
Query: 329 GAPGEG--------------------PEARGPSLGEDTKEADLPEPSE------------ 356
P E P+ P+ + T L EP+
Sbjct: 675 NTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELA 734
Query: 357 ----KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSP 412
K+P + KP P+ A K T + T ++ TLK +P
Sbjct: 735 PTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTP 794
Query: 413 KHPTPGSSDPLIQ--PSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
K P P P P+S P++PK + T + + + K T
Sbjct: 795 KKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTTPK--------KPAPTT 846
Query: 471 PRGAAP-PGQKGQANATRIPAKTPPAP--KTPPSSGEP-PKSGDRSGYSSPGSPGTPGSR 526
P P + T+ P +P TP S EP PK+ + +SP PG P ++
Sbjct: 847 PETPPPTTSEVSTPTTTKEPTTIHKSPDESTPELSAEPTPKALE----NSPKEPGVPTTK 902
Query: 527 SRTPSLPTPPTREPKKVAV--VRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGST 580
+ + P T K +RT P++ ++A T K +SKI +T
Sbjct: 903 TPAATKPEMTTTAKDKTTERDLRTTPETTTAAPK--MTKETATTTEKTTESKITAT 956
Score = 58.5 bits (140), Expect = 2e-08
Identities = 83/347 (23%), Positives = 129/347 (37%), Gaps = 46/347 (13%)
Query: 214 SKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
+KE E ++ ++ Q S DG+ T+A+E SI A+ P S
Sbjct: 279 NKETTVETKETTTTNKQTST--------DGKEKTTSAKETQSIEKTSAKDLAPT-----S 325
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE 333
KV + P + + + G A T E TP KE A + + P
Sbjct: 326 KVLAK-PTPKAETTTKGPA--------LTTPKEPTPTTPKEPASTTP---KEPTPTTIKS 373
Query: 334 GPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKA 393
P TK A + K+PA +P P+ A +K T + K A
Sbjct: 374 APTTPKEPAPTTTKSAPT---TPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTT--KSA 428
Query: 394 KTSTRSSAKTLKNRPC-LSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
T+ + A T +P +PK P P + + +P EP + K + T + +
Sbjct: 429 PTTPKEPAPTTPKKPAPTTPKEPAPTTP----KEPTPTTPKEPAPTTKEPAPTTPKEPAP 484
Query: 453 GAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKT----PPSSGEPPKS 508
A + + TP+ AP K + T PAP T P ++ EP +
Sbjct: 485 TAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTT----PKEPAPTTTKSAPTTTKEPAPT 540
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPPT-REPKKVAVVRTPPKSPS 554
+S ++P P ++ P+ P P PKK A T PK P+
Sbjct: 541 TTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPA--PTTPKEPA 585
Score = 57.8 bits (138), Expect = 4e-08
Identities = 126/586 (21%), Positives = 194/586 (33%), Gaps = 114/586 (19%)
Query: 50 TPTEDGSEEPG--SETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAG 107
TP E P + T+ K TPT + AP P K A P P TT EE
Sbjct: 604 TPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTT----PEKPAPTTPEELAP--TTPEEP- 656
Query: 108 IGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT 167
TP+ +E A P + K +EP AP P+ P T
Sbjct: 657 ---TPTTPEEPA------PTTPKAAAPNTPKEP---------------APTTPKEPAPTT 692
Query: 168 -RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDE 226
++P+ T P++T AP K L + P ++P KE
Sbjct: 693 PKEPAPTTPKET-----APTTPKGTAPTTLKEPAPTTP-----KKPAPKELAPTTTKEPT 742
Query: 227 SSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA----EGAIPLPVDFLSKVSTEIPAS 282
S+ D P A G P T A + P PA +G P + + + + PA
Sbjct: 743 STTCDKP---APTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAP 799
Query: 283 EPDGPSVGR---AKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARG 339
+ P+ + + D P T E P KE A + P P P
Sbjct: 800 KELAPTTTKGPTSTTSDKPAPTT-PKETAPTTPKEPAPTTPKKPAPTTPETPP--PTTSE 856
Query: 340 PSLGEDTKEADL----PEPSEKQPAAAPRGKPVSR------VPQLKARMVSKSKDGTGSD 389
S TKE P+ S + +A P K + VP K +K + T +
Sbjct: 857 VSTPTTTKEPTTIHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAK 916
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
DK + R++ +T P ++ + A E + K ++ T T
Sbjct: 917 DKTTERDLRTTPETTTAAPKMTKE---------------TATTTEKTTESKITATTTQVT 961
Query: 450 GSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSG 509
++ K KT P+ T+ T P + +P
Sbjct: 962 STTTQDTTPFKITTLKTTTLAPK----------VTTTKKTITTTEIMNKPEETAKPK--- 1008
Query: 510 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTP--------PKSPSSAKSRLQ 561
DR+ S++ TP P PT+ PKK + P PK+ + +
Sbjct: 1009 DRA----------TNSKATTPK-PQKPTKAPKKPTSTKKPKTMPRVRKPKTTPTPRKMTS 1057
Query: 562 TAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQIINKKLDLSNVQSK 607
T P P + ++ + +T P V++ K D + +
Sbjct: 1058 TMPELNPTSRIAEAMLQTTTRPNQTPNSKLVEVNPKSEDAGGAEGE 1103
Score = 53.5 bits (127), Expect = 7e-07
Identities = 82/363 (22%), Positives = 131/363 (36%), Gaps = 49/363 (13%)
Query: 216 EEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKV 275
EE+ E+ V E+ S S +S + R +++ A + E L V K
Sbjct: 152 EEITEEHSVSENQESSSSSSSSSSSSTIRKIKSSKNSAAN-----RELQKKLKVKDNKKN 206
Query: 276 STEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA----FPGAP 331
T+ + P P V A +F T Q + + + A P P
Sbjct: 207 RTKKKPT-PKPPVVDEAGSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLP 265
Query: 332 GEGPEARGPSLG---EDTKEADLPEPSEKQPAAAPRGKPVSR-----VPQLKARMVSKSK 383
++ SL E T E + KQ + + K S + + A+ ++ +
Sbjct: 266 PNSDTSKETSLTVNKETTVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTS 325
Query: 384 DGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVS 443
KA+T+T+ A T +PK PTP + P PA ++PK +
Sbjct: 326 KVLAKPTPKAETTTKGPALT-------TPKEPTPTT------PKEPA-----STTPKEPT 367
Query: 444 SVTSRTGSSGAKEMKLKGADGKTKIA--TPRGAAPPGQKGQANATRIPAKTPPAPKTPPS 501
T ++ + KE A TK A TP+ AP T+ PA T P P +
Sbjct: 368 PTTIKSAPTTPKEP----APTTTKSAPTTPKEPAP-------TTTKEPAPTTPKEPAPTT 416
Query: 502 SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQ 561
+ EP + +S ++P P + P+ P P K TP + + K
Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 562 TAP 564
T P
Sbjct: 477 TTP 479
Score = 52.4 bits (124), Expect = 2e-06
Identities = 58/216 (26%), Positives = 86/216 (39%), Gaps = 33/216 (15%)
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT--PGSSDPLIQPSSP-------AVCPEP 435
G+G D+ K +T ++ T N+ SPK T P + P + P+S V E
Sbjct: 223 GSGLDNGDFKVTTPDTSTTQHNKVSTSPKITTAKPINPRPSLPPNSDTSKETSLTVNKET 282
Query: 436 PSSPKHVSSVTSRTGSSG------AKE-MKLKGADGKTKIATPRGAAPPGQKGQANATRI 488
K ++ +T + G AKE ++ K T + A P K + T+
Sbjct: 283 TVETKETTTTNKQTSTDGKEKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAE-TTTKG 341
Query: 489 PAKTPPAPKTP-----PSSGEPPKSGDRSGYSSPGSPGTPG-----SRSRTPSLPTPPTR 538
PA T P TP P+S P + + S+P +P P S TP P P T
Sbjct: 342 PALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTT 401
Query: 539 E------PKKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
+ PK+ A T +P++ KS T P P
Sbjct: 402 KEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAP 437
Score = 35.4 bits (80), Expect = 0.20
Identities = 69/273 (25%), Positives = 94/273 (34%), Gaps = 44/273 (16%)
Query: 36 EGDTDAGLKESPLQTPTEDGSEE--------PGSETSDAKSTPTAEDVTAPLV-DEGAPG 86
+G LKE TP + +E P S TSD K PT TAP E AP
Sbjct: 779 KGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSD-KPAPTTPKETAPTTPKEPAPT 837
Query: 87 KQAAAQPHT-EIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL 145
P T E P TT+E + TP+ E ES + EP P L
Sbjct: 838 TPKKPAPTTPETPPPTTSEVS----TPTTTKEPTTIHKSPDESTPELS----AEPTPKAL 889
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKG 205
+ PG P T+ P+ T PE T + + + P +
Sbjct: 890 ENSPKE--PGVP--------TTKTPAATKPEMTTTAKDKTTERDLRTTPETTTAAPKMT- 938
Query: 206 AGGKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDG--RPPQTAARE---AT 254
KE + E+ E + V ++ QD+ P K + + P T ++ T
Sbjct: 939 ---KETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLAPKVTTTKKTITTT 995
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP 287
I P E A P SK +T P P
Sbjct: 996 EIMNKPEETAKPKDRATNSKATTPKPQKPTKAP 1028
>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
Length = 1466
Score = 77.8 bits (190), Expect = 3e-14
Identities = 131/525 (24%), Positives = 166/525 (31%), Gaps = 132/525 (25%)
Query: 56 SEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE--------EAG 107
S PGS S P E A G PG A P P G E E G
Sbjct: 188 SGHPGSPGSPGYQGPPGEPGQAG--PSGPPGPPGAIGPSG--PAGKDGESGRPGRPGERG 243
Query: 108 IGDTPSLEDEAA--GHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG-----APLLP 160
+ P ++ A G + G + G E G PGL + +G+PG P+ P
Sbjct: 244 LPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKGE--NGLPGENGAPGPMGP 301
Query: 161 EG-PREATRQ--PSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEE 217
G P E R P G +G R + G GPP AG PG+K E
Sbjct: 302 RGAPGERGRPGLPGAAGARGNDGARGSD--------GQPGPPGPP-GTAGFPGSPGAKGE 352
Query: 218 VDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVST 277
V P SP S +P Q G P A PG P P +
Sbjct: 353 V---------GPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPGGKGEMG---- 399
Query: 278 EIPASEPDGPSVGRAKGQDAPLEFTFHV-------EITPNVQKEQAHSEEHLGRAAFPGA 330
PA P P + A+G P E N K + G A PG
Sbjct: 400 --PAGIPGAPGLMGARGPPGPAGANGAPGLRGGAGEPGKNGAKGEPGPRGERGEAGIPGV 457
Query: 331 PGEGPEARGPSLGEDTKEADLPEPSEK--QPAAAPRGKPVSRVPQLKARMVSKSKDGTGS 388
PG + GED K+ EP AA RG P R P
Sbjct: 458 PG--------AKGEDGKDGSPGEPGANGLPGAAGERGAPGFRGP---------------- 493
Query: 389 DDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
+ + PG P + +P P+ P+ + R
Sbjct: 494 ----------------------AGPNGIPGEKGPAGERGAPG-----PAGPRGAAGEPGR 526
Query: 449 TGSSGAKEMKLK-------GADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA------ 495
G G M+ G+DGK PPG +G++ P + P
Sbjct: 527 DGVPGGPGMRGMPGSPGGPGSDGKP--------GPPGSQGESGRPGPPGPSGPRGQPGVM 578
Query: 496 --PKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT-PSLPTPPT 537
P + G P K+G+R G PG G PG T P P PT
Sbjct: 579 GFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPT 623
Score = 68.9 bits (167), Expect = 2e-11
Identities = 148/583 (25%), Positives = 183/583 (31%), Gaps = 117/583 (20%)
Query: 13 DHAGTYGLGDRKDQG--GYTMHQDQEGDTDAGLKESPLQTPTEDGSEE-PGSETSDAKST 69
+ G G G + G G T Q G T G + P G + PG+ ++
Sbjct: 595 ERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPPGPQGLQGLPGTGGPPGENG 654
Query: 70 PTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEA--GIGDTPSLEDEAAGHVTQEPE 127
E P D GAPG P + G E G+ P L A PE
Sbjct: 655 KPGEP--GPKGDAGAPGA-----PGGKGDAGAPGERGPPGLAGAPGLRGGAG---PPGPE 704
Query: 128 SGKVVQEGFLREPGPPGLSHQL-MSGMPG--APLLPEGPREATRQPSGTGPEDTEG--GR 182
GK G PGPPG + + GMPG L GP+ +P G G + G G
Sbjct: 705 GGK----GAAGPPGPPGAAGTPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGP 760
Query: 183 HAPELLKHQLLGDLHQEGPPL----KGAGGKER-PGSKEEVDEDRDVDESSPQDSPPSKA 237
P G + GP KG GG PG + E+ P
Sbjct: 761 RGPT-------GPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPG 813
Query: 238 SPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
+P Q+G P R A PG EG P V+ S P GP
Sbjct: 814 APGQNGEPGGKGERGA---PGEKGEGGPP-------GVAGPPGGSGPAGPP--------- 854
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPG-EGPEARGPSLGEDTKEADLPEPSE 356
P K + S G A FPGA G GP + G P PS
Sbjct: 855 ----------GPQGVKGERGSPGGPGAAGFPGARGLPGPPGSNGNPGP-------PGPSG 897
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPT 416
P G P + VS K G +K +
Sbjct: 898 SPGKDGPPG-PAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGP---------------- 940
Query: 417 PGSSDPLIQP--------SSPAVCPEPPSSPKHVSSVTSRTGSSGAK-EMKLKGADGKTK 467
PG+ PL + P P P SP G G K E GA+G +
Sbjct: 941 PGAPGPLGIAGITGARGLAGPPGMPGPRGSP----------GPQGVKGESGKPGANGLSG 990
Query: 468 IATPRGAAPPGQKGQANATRIPAK--TPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGS 525
P G P G G A P + P + P G P GDR SPG+PG PG
Sbjct: 991 ERGPPG--PQGLPGLAGTAGEPGRDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGH 1048
Query: 526 RSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMP 568
P P P K + P P+ A + P P
Sbjct: 1049 ----PGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP 1087
Score = 59.7 bits (143), Expect = 1e-08
Identities = 125/537 (23%), Positives = 165/537 (30%), Gaps = 93/537 (17%)
Query: 83 GAPGKQAAAQPHTEIPEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGFLREPG 141
G PG AA T +G E G+G P + G + GK G G
Sbjct: 711 GPPGPPGAAG--TPGLQGMPGERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIG 768
Query: 142 PPGLSHQLMS-GMPGAPLLP--EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
PPG + Q G GAP LP GPR + + TGP G AP Q
Sbjct: 769 PPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETGPPGPAGFPGAPG-----------Q 817
Query: 199 EGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPG 258
G P GGK G+ E E + P P G + + G
Sbjct: 818 NGEP----GGKGERGAPGEKGEGGPPGVAGPPGGSGPAGPPGPQGVKGERGSPGGPGAAG 873
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASE--PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA 316
FP +P P P S P P + G+D P
Sbjct: 874 FPGARGLPGP-----------PGSNGNPGPPGPSGSPGKDGPP----------------- 905
Query: 317 HSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKA 376
G A GAPG P GP G+ + + P + P AP ++ + +
Sbjct: 906 ------GPAGNTGAPGS-PGVSGPK-GDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG 957
Query: 377 RMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPP 436
G S LS + PG P P EP
Sbjct: 958 LAGPPGMPGPRGSPGPQGVKGESGKPGANG---LSGERGPPG---PQGLPGLAGTAGEPG 1011
Query: 437 SSPKHVSS-VTSRTGSSGAK----EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAK 491
S + R GS G K E GA G P G P K PA
Sbjct: 1012 RDGNPGSDGLPGRDGSPGGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAG 1071
Query: 492 TPPAPKTPPSSGEPPKSGDRS-----------------GY-SSPGSPGTPGSRSRTPSLP 533
AP S G P G R G+ +PG+PG+PG + ++
Sbjct: 1072 PAGAPGPAGSRGAPGPQGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIG 1131
Query: 534 TPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKH--QPG 588
+P P+ PP ++ P+ P + + + GS + H QPG
Sbjct: 1132 SPGPAGPRGPVGPSGPPGKDGTSG---HPGPIGPPGPRGNRGERGSEGSPGHPGQPG 1185
Score = 54.3 bits (129), Expect = 4e-07
Identities = 115/451 (25%), Positives = 143/451 (31%), Gaps = 107/451 (23%)
Query: 140 PGPPGLS-HQLMSGMPG-----------APLLPEGPREATRQPSGTGPEDTEGGRHAPEL 187
PGPPG S H G PG P P GP A PSG +D E GR
Sbjct: 182 PGPPGTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIG-PSGPAGKDGESGRPGRP- 239
Query: 188 LKHQLLGDLHQEGPP-LKG-AGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRP 245
G+ GPP +KG AG PG K D E +P K ++G P
Sbjct: 240 ------GERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNGEKGETGAPGLKG---ENGLP 290
Query: 246 PQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHV 305
+ A G P E P P A+G D
Sbjct: 291 GENGAPGPMGPRGAPGE------------------RGRPGLPGAAGARGNDGA------- 325
Query: 306 EITPNVQKEQAHSEEHLGRAAFPGAPGE----GPEARGPSLGEDTKEADLPEPSEKQPAA 361
Q G A FPG+PG GP S G + + P P A
Sbjct: 326 ----RGSDGQPGPPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGE-PGPQGHAGAQ 380
Query: 362 APRGKP-VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSS 420
P G P ++ P K M G + P + + PG
Sbjct: 381 GPPGPPGINGSPGGKGEMGPAGIPGA------------PGLMGARGPPGPAGANGAPGLR 428
Query: 421 DPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLK-------GADGKTKIATPRG 473
+P EP P+ G GAK K GA+G A RG
Sbjct: 429 GGAGEPGKNGAKGEP--GPRGERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERG 486
Query: 474 AAPPGQKGQANATRIPAKTPPA-------PKTPP-SSGEPPKSG------------DRSG 513
A PG +G A IP + PA P P ++GEP + G G
Sbjct: 487 A--PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGG 544
Query: 514 YSSPGSPGTPGSRSRT----PSLPTPPTREP 540
S G PG PGS+ + P P+ P +P
Sbjct: 545 PGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575
Score = 39.3 bits (90), Expect = 0.014
Identities = 48/190 (25%), Positives = 61/190 (32%), Gaps = 45/190 (23%)
Query: 345 DTKEADLPEPSEK---------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKT 395
D +E D P P QP AP P + PQ G D
Sbjct: 68 DDQELDCPNPEIPFGECCAVCPQPPTAPTRPPNGQGPQ-----------GPKGDPGPPGI 116
Query: 396 STRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVS-SVTSRTGSSGA 454
R+ + +P +PGS P P +C P+ P++ S S SG
Sbjct: 117 PGRNGDPGIPGQP------GSPGS------PGPPGICESCPTGPQNYSPQYDSYDVKSGV 164
Query: 455 KEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGY 514
L G G P G PPG G P +P +P G P + G
Sbjct: 165 AVGGLAGYPGPAGPPGPPG--PPGTSGH----------PGSPGSPGYQGPPGEPGQAGPS 212
Query: 515 SSPGSPGTPG 524
PG PG G
Sbjct: 213 GPPGPPGAIG 222
Score = 35.4 bits (80), Expect = 0.20
Identities = 39/140 (27%), Positives = 52/140 (37%), Gaps = 19/140 (13%)
Query: 430 AVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIP 489
AVCP+PP++P + G G + G G+ P PG G I
Sbjct: 86 AVCPQPPTAPTRPPNGQGPQGPKG--DPGPPGIPGRN--GDPGIPGQPGSPGSPGPPGIC 141
Query: 490 AKTPPAPK--TPPSSGEPPKSG----DRSGYSSP----GSPGTPGSRSRTPSLPTP---- 535
P P+ +P KSG +GY P G PG PG+ S +P
Sbjct: 142 ESCPTGPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGPPGPPGTSGHPGSPGSPGYQG 201
Query: 536 PTREPKKVAVVRTPPKSPSS 555
P EP + A PP P +
Sbjct: 202 PPGEPGQ-AGPSGPPGPPGA 220
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 75.5 bits (184), Expect = 2e-13
Identities = 132/506 (26%), Positives = 165/506 (32%), Gaps = 75/506 (14%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
AG+K S L+ E E GS P E P D G G P E P G
Sbjct: 1949 AGIKASALREIVETWDESSGS------FLPVPERRRGPKGDSGEQGP-----PGKEGPIG 1997
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLP 160
E GD + + E G G EPG PG+ PG P
Sbjct: 1998 FPGERGLKGDRGDPGPQGPPGLALG-ERGPPGPSGLAGEPGKPGI--------PGLPGRA 2048
Query: 161 EGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPP-LKGAGGKERP-GSKEEV 218
G EA R P G +G R G+ ++GPP L G G P G K V
Sbjct: 2049 GGVGEAGR-PGERGERGEKGER-----------GEQGRDGPPGLPGTPGPPGPPGPKVSV 2096
Query: 219 DEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLP--VDFLSKVS 276
DE S Q P K + + G + +PG + P P D +
Sbjct: 2097 DEPGP-GLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKGDRGEPGPRGQDGNPGLP 2155
Query: 277 TEIPASEPDG-PSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-G 334
E + P+G P + +G P+ H + P A G + G PGE G
Sbjct: 2156 GERGMAGPEGKPGLQGPRGPPGPVGG--HGDPGPPGAPGLAGPAGPQGPSGLKGEPGETG 2213
Query: 335 PEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKA 393
P RG L T LP P P+G P L ++ K G G D
Sbjct: 2214 PPGRG--LTGPTGAVGLPGPPGPSGLVGPQGSP-----GLPGQVGETGKPGAPGRDGASG 2266
Query: 394 KTSTRSSAKTLKNRPCLSPKHP-TPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSS 452
K R S P P +PG P+ P P + + G+
Sbjct: 2267 KDGDRGS-----------PGVPGSPGLPGPVGPKGEPGPTGAPGQAVVGLPGAKGEKGAP 2315
Query: 453 GAKEMKL---KGADGKTKIATPRG-------AAPPGQKGQANATRIPA----KTPPAPKT 498
G L GA G + PRG A PG G+ P K P
Sbjct: 2316 GGLAGDLVGEPGAKGDRGLPGPRGEKGEAGRAGEPGDPGEDGQKGAPGPKGFKGDPGVGV 2375
Query: 499 PPSSGEPPKSGDRSGYSSPGSPGTPG 524
P S G P G + PG PG PG
Sbjct: 2376 PGSPGPPGPPGVKGDLGLPGLPGAPG 2401
Score = 67.4 bits (163), Expect = 5e-11
Identities = 135/542 (24%), Positives = 179/542 (33%), Gaps = 72/542 (13%)
Query: 73 EDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVV 132
+ + P G PGK P + G + GD ED G SG+
Sbjct: 1817 QGLPGPSGPPGLPGK-----PGEDGKPGLNGKNGEPGDPG--EDGRKGEKGDSGASGREG 1869
Query: 133 QEGFLREPGPPG-LSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQ 191
++G E G PG L Q G+PG P+ P G + P GTGP+ G + +
Sbjct: 1870 RDGPKGERGAPGILGPQGPPGLPG-PVGPPG-QGFPGVPGGTGPKGDRGETGSKG--EQG 1925
Query: 192 LLGDLHQEGPP---------LKGAGGK------------ERPGSKEEVDEDRDVDES-SP 229
L G+ G P L+ AG K E GS V E R + S
Sbjct: 1926 LPGERGLRGEPGSVPNVDRLLETAGIKASALREIVETWDESSGSFLPVPERRRGPKGDSG 1985
Query: 230 QDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSV 289
+ PP K P G P + + PG +G L + A EP P +
Sbjct: 1986 EQGPPGKEGPI--GFPGERGLKGDRGDPG--PQGPPGLALGERGPPGPSGLAGEPGKPGI 2041
Query: 290 ----GRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
GRA G E E +K + + G PG PG P GP + D
Sbjct: 2042 PGLPGRAGGVG---EAGRPGERGERGEKGERGEQGRDGPPGLPGTPGP-PGPPGPKVSVD 2097
Query: 346 TKEADLPEPSEKQPAAAPRGKPVSR----------VPQLKARMVSKSKDGTGSDDKKAKT 395
L +G+P S VP +K + + G D
Sbjct: 2098 EPGPGLSGEQGPPGLKGAKGEPGSNGDQGPKGDRGVPGIKG---DRGEPGPRGQDGNPGL 2154
Query: 396 STRSSAKTLKNRPCLS----PKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGS 451
+ +P L P P G DP P +P + P+ P+ S + G
Sbjct: 2155 PGERGMAGPEGKPGLQGPRGPPGPVGGHGDPG-PPGAPGLAG--PAGPQGPSGLKGEPGE 2211
Query: 452 SGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA--PKTPPSSGEPPKSG 509
+G L G G + P G P G G + +P + P P G K G
Sbjct: 2212 TGPPGRGLTGPTGAVGLPGPPG--PSGLVGPQGSPGLPGQVGETGKPGAPGRDGASGKDG 2269
Query: 510 DRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPD 569
DR PGSPG PG P PT P + V K A L V P
Sbjct: 2270 DRGSPGVPGSPGLPGPVG--PKGEPGPTGAPGQAVVGLPGAKGEKGAPGGLAGDLVGEPG 2327
Query: 570 LK 571
K
Sbjct: 2328 AK 2329
Score = 65.1 bits (157), Expect = 2e-10
Identities = 116/474 (24%), Positives = 147/474 (31%), Gaps = 86/474 (18%)
Query: 78 PLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFL 137
P D G PG+ A P T E G G+ G
Sbjct: 1270 PPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGA----------------DGRPGSPGRA 1313
Query: 138 REPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLH 197
PG PG G+ G+P LP GPR P GP +G AP Q++G
Sbjct: 1314 GNPGTPGAP-----GLKGSPGLP-GPRG---DPGERGPRGPKGEPGAPG----QVIGG-- 1358
Query: 198 QEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIP 257
EGP L G G PG + + P+ PP A G R P
Sbjct: 1359 -EGPGLPGRKGD--PGPSGPPGPRGPLGDPGPR-GPPGLPGTAMKGDKGDRGERG----P 1410
Query: 258 GFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAH 317
P EG I EP P + + G P+ P + E+
Sbjct: 1411 PGPGEGGIA--------------PGEPGLPGLPGSPGPQGPVG-------PPGKKGEKGD 1449
Query: 318 SEEHL-GRAAFPGAPGEG-----PEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRV 371
SE+ G PG+PGE P A GP G+ L E EK P +
Sbjct: 1450 SEDGAPGLPGQPGSPGEQGPRGPPGAIGPK-GDRGFPGPLGEAGEKGERGPPGPAGSRGL 1508
Query: 372 PQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV 431
P + R +K +G + R K RP P P +
Sbjct: 1509 PGVAGRPGAKGPEGPPGP------TGRQGEKGEPGRP------GDPAVVGPAVAGPKGEK 1556
Query: 432 CPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRG----AAPPGQKGQANATR 487
P+ P+ + V G G G G P G A PPG G
Sbjct: 1557 GDVGPAGPRGATGVQGERGPPGLVLPGDPGPKGDPGDRGPIGLTGRAGPPGDSGPPGEKG 1616
Query: 488 IPAKT-PPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
P + PP P P G + G++ PG PG PG P R P
Sbjct: 1617 DPGRPGPPGPVGP--RGRDGEVGEKGDEGPPGDPGLPGKAGERGLRGAPGVRGP 1668
Score = 52.4 bits (124), Expect = 2e-06
Identities = 139/568 (24%), Positives = 176/568 (30%), Gaps = 119/568 (20%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSE-EPGSETSDAKSTPTAED 74
G GL R G + ++GD P+ DG E G E
Sbjct: 1595 GPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPVGPRGRDGEVGEKGDE------------ 1642
Query: 75 VTAPLVDEGAPGKQAA----AQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGK 130
P D G PGK P P G ++ G ED G G
Sbjct: 1643 --GPPGDPGLPGKAGERGLRGAPGVRGPVGEKGDQGDPG-----EDGRNG------SPGS 1689
Query: 131 VVQEGFLREPGPPGLSHQLMSGMPGAPLL----------PEGPREATRQPSGTGPEDTEG 180
+G EPGPPG +L+ PGA P GP+ P G EG
Sbjct: 1690 SGPKGDRGEPGPPGPPGRLVDTGPGAREKGEPGDRGQEGPRGPKGDPGLPGAPGERGIEG 1749
Query: 181 GRHAP----ELLKHQLLGDLHQEGPP-LKGAGGKE-RPGSKEEVDEDRDVDESSPQDSPP 234
R P + G+ GPP L G G + +PG+ S P +
Sbjct: 1750 FRGPPGPQGDPGVRGPAGEKGDRGPPGLDGRSGLDGKPGA---------AGPSGPNGAAG 1800
Query: 235 SKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKG 294
P +DG P R +PG +P K EP P KG
Sbjct: 1801 KAGDPGRDGLP---GLRGEQGLPGPSGPPGLPGKPGEDGKPGLNGKNGEPGDPGEDGRKG 1857
Query: 295 QDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARG-PSL-GEDTKEADL 351
+ + + K + + LG PG PG GP +G P + G + D
Sbjct: 1858 EKG--DSGASGREGRDGPKGERGAPGILGPQGPPGLPGPVGPPGQGFPGVPGGTGPKGDR 1915
Query: 352 PEPSEKQPAAAP-----RGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKN 406
E K P RG+P S VP + D+ +T + K
Sbjct: 1916 GETGSKGEQGLPGERGLRGEPGS-VPNV---------------DRLLET---AGIKASAL 1956
Query: 407 RPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSG----AKEMKLKGA 462
R + + GS P+ PE PK S G G E LKG
Sbjct: 1957 REIVETWDESSGSFLPV---------PERRRGPKGDSGEQGPPGKEGPIGFPGERGLKGD 2007
Query: 463 DGKTKIATPRGAA-----PPGQKGQANATRIPAKTPPAP---------KTPPSSGEPPKS 508
G P G A PPG G A P P P P GE +
Sbjct: 2008 RGDPGPQGPPGLALGERGPPGPSGLAGEPGKPG-IPGLPGRAGGVGEAGRPGERGERGEK 2066
Query: 509 GDRSGYSSPGSPGTPGSRSRTPSLPTPP 536
G+R G PG PG TP P PP
Sbjct: 2067 GERGEQGRDGPPGLPG----TPGPPGPP 2090
Score = 49.3 bits (116), Expect = 1e-05
Identities = 126/523 (24%), Positives = 166/523 (31%), Gaps = 113/523 (21%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGK--VVQEGFLR 138
+ GA G + P E E A E G P ED G + G V G
Sbjct: 2325 EPGAKGDRGLPGPRGEKGEAGRAGEPG---DPG-EDGQKGAPGPKGFKGDPGVGVPGSPG 2380
Query: 139 EPGPPGLSHQL-MSGMPGAPLL-----PEGPREATRQPSGTGPEDTEG--GRHAPELLKH 190
PGPPG+ L + G+PGAP + GPR QP +G G GR
Sbjct: 2381 PPGPPGVKGDLGLPGLPGAPGVVGFPGQTGPRGEMGQPGPSGERGLAGPPGREG------ 2434
Query: 191 QLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAA 250
+ G L GPP G+ G + D V P+ +DGRP Q
Sbjct: 2435 -IPGPLGPPGPP--GSVGPPGASGLKGDKGDPGVGLPGPRGERGEPGIRGEDGRPGQEGP 2491
Query: 251 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPN 310
R T PG E + VG A
Sbjct: 2492 RGLTGPPGSRGERG--------------------EKGDVGSA-----------------G 2514
Query: 311 VQKEQAHSEEHLGRAAFPGAPGEGPEARGPSL--GEDTKEADLPEPSEKQPAAAPRGKPV 368
++ ++ S LG GA G+ E RGP G+ D +P +K P K
Sbjct: 2515 LKGDKGDSAVILGPPGPRGAKGDMGE-RGPRGLDGDKGPRGDNGDPGDKGSKGEPGDKGS 2573
Query: 369 SRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSS 428
+ +P L+ + + + G A + P K PG I+
Sbjct: 2574 AGLPGLRGLLGPQGQPG---------------AAGIPGDPGSPGKDGVPG-----IRGEK 2613
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLK-GADGKTKIATPRGA-APPGQKGQANAT 486
V P K V G G K K + G G+ +A +G PG GQ+ A
Sbjct: 2614 GDVGFMGPRGLKGERGVKGACGLDGEKGDKGEAGPPGRPGLAGHKGEMGEPGVPGQSGA- 2672
Query: 487 RIPAKT-------------PPAPK----------TPPSSGEPPKSGDRSGYSSPGSPGTP 523
P K P PK TP G P SG+ PG PG+
Sbjct: 2673 --PGKEGLIGPKGDRGFDGQPGPKGDQGEKGERGTPGIGGFPGPSGNDGSAGPPGPPGSV 2730
Query: 524 GSRSRTPSLPTPPTREPKKVAVVRTP--PKSPSSAKSRLQTAP 564
G R R P VV P P +P + + P
Sbjct: 2731 GPRGPEGLQGQKGERGPPGERVVGAPGVPGAPGERGEQGRPGP 2773
Score = 36.2 bits (82), Expect = 0.12
Identities = 37/130 (28%), Positives = 47/130 (36%), Gaps = 30/130 (23%)
Query: 419 SSDPLIQPSSPAVCP-----EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRG 473
S D + + A+C +P P V + G G EM L+G G
Sbjct: 1221 SLDQAVSGLATALCQASFTTQPRPEPCPVYCPKGQKGEPG--EMGLRGQVG--------- 1269
Query: 474 AAPPGQKGQANATRIPA-KTPPAPKT-------PPSSGEPPKSGDRSGYSSPGSPGTPGS 525
PPG G T P + PP T P + G P G +PG+PG GS
Sbjct: 1270 --PPGDPGLPGRTGAPGPQGPPGSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGLKGS 1327
Query: 526 RSRTPSLPTP 535
P LP P
Sbjct: 1328 ----PGLPGP 1333
Score = 35.4 bits (80), Expect = 0.20
Identities = 35/133 (26%), Positives = 46/133 (34%), Gaps = 16/133 (12%)
Query: 435 PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT-- 492
PP P + RTG+ G + A K + P PG G+A P
Sbjct: 1270 PPGDP----GLPGRTGAPGPQGPP-GSATAKGERGFPGADGRPGSPGRAGNPGTPGAPGL 1324
Query: 493 PPAPKTPPSSGEPPKSGDRSGYSSPGS---------PGTPGSRSRTPSLPTPPTREPKKV 543
+P P G+P + G R PG+ PG PG + P R P
Sbjct: 1325 KGSPGLPGPRGDPGERGPRGPKGEPGAPGQVIGGEGPGLPGRKGDPGPSGPPGPRGPLGD 1384
Query: 544 AVVRTPPKSPSSA 556
R PP P +A
Sbjct: 1385 PGPRGPPGLPGTA 1397
Score = 31.2 bits (69), Expect = 3.7
Identities = 21/56 (37%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 482 QANATRIPAKTPPAPKTPPSS-GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP 536
QA+ T P P P GEP + G R PG PG PG R+ P PP
Sbjct: 1235 QASFTTQPRPEPCPVYCPKGQKGEPGEMGLRGQVGPPGDPGLPG-RTGAPGPQGPP 1289
>gi|5174573 myeloid/lymphoid or mixed-lineage leukemia trithorax
homolog 2 [Homo sapiens]
Length = 1210
Score = 74.7 bits (182), Expect = 3e-13
Identities = 135/616 (21%), Positives = 211/616 (34%), Gaps = 112/616 (18%)
Query: 32 HQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAA 91
H + + T + L++ + +ED E E + S P P + P A+A
Sbjct: 412 HSNSQQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAP-------PSAPQSLPEPVASA 464
Query: 92 QPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS 151
++AE D+ S D + + + E + + E EP PP + +
Sbjct: 465 -------HSSSAESESTSDSDSSSDSESESSSSDSEENEPL-ETPAPEPEPPTTNKWQLD 516
Query: 152 ------GMPGAPLLPEGPREA---TRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPP 202
P AP PEGPR R P G D+ + E + PP
Sbjct: 517 NWLTKVSQPAAP--PEGPRSTEPPRRHPESKGSSDSATSQEHSE-----------SKDPP 563
Query: 203 LKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK--ASPAQDGRPPQTAAR--EATSIPG 258
K + R + R +S Q PP + Q +P + +AR TS+ G
Sbjct: 564 PKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQG 623
Query: 259 FPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHS 318
G LP + S + P + G A + P + P+ +K++ S
Sbjct: 624 EREPGL--LPYGSRDQTSKDKPKVKTKGRPRAAASNEPKP-------AVPPSSEKKKHKS 674
Query: 319 EEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARM 378
P GP +D E PE P +G P S
Sbjct: 675 ----------SLPAPSKALSGPEPAKDNVEDRTPEHFALVPLTESQGPPHS--------- 715
Query: 379 VSKSKDGTGSDD---KKAKTSTRSSAK-----TLKNRPCLSPKHPTPGSSDPLIQPSSPA 430
G+GS ++A S K L++ LSP TP +++ +
Sbjct: 716 ------GSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITLDL 769
Query: 431 V--CPEPPSSPKHVSSVTSRTGSSGAKEMKLK-GADGKTKIATPRGAAPPGQKGQANATR 487
+ P+PP + +G K K +D +K+A R KG+A
Sbjct: 770 LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKR-------KGEAERDC 822
Query: 488 IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPP----TREPKKV 543
K + S S S + P P + S+ LP PP +++P K
Sbjct: 823 DNKKIRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKE--MLPPPPVSSSSQKPAKP 880
Query: 544 AVVRT----------PPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGGKVQ 593
A+ R+ PPKS SS KS + + +P + V+ K GS + +H+ G
Sbjct: 881 ALKRSRREADTCGQDPPKSASSTKSNHKDSSIPKQ--RRVEGK-GSRSSSEHKGSSGDTA 937
Query: 594 IINKKLDLSNVQSKCG 609
L N SK G
Sbjct: 938 NPFPVPSLPNGNSKPG 953
Score = 67.0 bits (162), Expect = 6e-11
Identities = 83/382 (21%), Positives = 136/382 (35%), Gaps = 36/382 (9%)
Query: 223 DVDESSPQDSPPSKASPAQ---------DGRPPQTAAREATSIPGFPAEGAIPLPVDFLS 273
D + +P +SP K P D + P A +P E V +
Sbjct: 298 DGQDQAPSESPELKPLPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVE 357
Query: 274 KVSTEIPASEPDGPSVGRAKGQDAPLEFTF------HVE-ITPNVQKEQAHSEEHLGRAA 326
++ E+ S P + P +F F HV +T N ++ S+ H
Sbjct: 358 EILKEMTHSWPPPLTAIHTPSTAEPSKFPFPTKDSQHVSSVTQNQKQYDTSSKTHSNSQQ 417
Query: 327 FPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRG--KPVSRVPQLKARMVSKSKD 384
+ E S D+++ PS P +AP+ +PV+ A S S
Sbjct: 418 GTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSAPPSAPQSLPEPVASAHSSSAESESTSDS 477
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGS---SDPLIQPSSPAVCPEPPSSP-- 439
+ SD + +S+ S P P+ PT + L + S PA PE P S
Sbjct: 478 DSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEGPRSTEP 537
Query: 440 --KHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPK 497
+H S S ++ + + K K+ PR G+ + + PA+ P +
Sbjct: 538 PRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSPAQQEPPQR 597
Query: 498 TPPSSGEPPK-------SGDRSGYSSPGSPG--TPGSRSRT-PSLPTPPTR-EPKKVAVV 546
+ +P K +G R+ PG GSR +T P T+ P+ A
Sbjct: 598 QTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKGRPRAAASN 657
Query: 547 RTPPKSPSSAKSRLQTAPVPMP 568
P P S++ + + +P P
Sbjct: 658 EPKPAVPPSSEKKKHKSSLPAP 679
Score = 60.1 bits (144), Expect = 8e-09
Identities = 88/365 (24%), Positives = 131/365 (35%), Gaps = 55/365 (15%)
Query: 225 DESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP 284
D+ +PQDS + A P PP + ++ ++ P A P+D + +E P +P
Sbjct: 255 DKETPQDSLVAPAQPPSQTFPPPSLPSKSVAMQQKPT--AYVRPMDGQDQAPSESPELKP 312
Query: 285 DGPSVGRAKGQDAPLEFTFHVEIT----PNVQKEQAHSEE-HLGRAAFPGAPGEGPEARG 339
+ + L+ ++T P+ EQ +S E H P
Sbjct: 313 LPEDYRQQTFEKTDLKVPAKAKLTKLKMPSQSVEQTYSNEVHCVEEILKEMTHSWP---- 368
Query: 340 PSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRS 399
P L + PS +P+ P P ++ VS D +KT + S
Sbjct: 369 PPL------TAIHTPSTAEPSKFP-------FPTKDSQHVSSVTQNQKQYDTSSKTHSNS 415
Query: 400 SAKT---LKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPK---------HVSSV-- 445
T L++ LS + P PSS A PPS+P+ H SS
Sbjct: 416 QQGTSSMLEDDLQLSDSEDSDSEQTPEKPPSSSA----PPSAPQSLPEPVASAHSSSAES 471
Query: 446 --TSRTGSSGAKEMKLKGADGK----TKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP 499
TS + SS E + +D + + P P K Q + P AP
Sbjct: 472 ESTSDSDSSSDSESESSSSDSEENEPLETPAPEPEPPTTNKWQLDNWLTKVSQPAAPPEG 531
Query: 500 PSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSR 559
P S EPP+ S SS + S S+ P PP K R PP++P K
Sbjct: 532 PRSTEPPRRHPESKGSSDSATSQEHSESKDP----PPKSSSK---APRAPPEAPHPGKRS 584
Query: 560 LQTAP 564
Q +P
Sbjct: 585 CQKSP 589
Score = 45.1 bits (105), Expect = 2e-04
Identities = 118/566 (20%), Positives = 183/566 (32%), Gaps = 135/566 (23%)
Query: 53 EDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPE------GTTAEEA 106
ED + SE SD++ TP E P A +PE ++AE
Sbjct: 424 EDDLQLSDSEDSDSEQTP-----------EKPPSSSAPPSAPQSLPEPVASAHSSSAESE 472
Query: 107 GIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSG------MPGAPLLP 160
D+ S D + + + E + ++ EP PP + + P AP P
Sbjct: 473 STSDSDSSSDSESESSSSDSEENEPLETP-APEPEPPTTNKWQLDNWLTKVSQPAAP--P 529
Query: 161 EGPREAT---RQPSGTGPEDTEGGRH---------------------APELLKHQLLGDL 196
EGPR R P G D+ + AP K
Sbjct: 530 EGPRSTEPPRRHPESKGSSDSATSQEHSESKDPPPKSSSKAPRAPPEAPHPGKRSCQKSP 589
Query: 197 HQEGPPLKGAGGKERP----------GSKEEVDEDRD---VDESSPQDSPPSKASPAQDG 243
Q+ PP + G ++P GS+ + +R+ + S + K G
Sbjct: 590 AQQEPPQRQTVGTKQPKKPVKASARAGSRTSLQGEREPGLLPYGSRDQTSKDKPKVKTKG 649
Query: 244 RPPQTAAREATSIPGFPA-------EGAIPLPVDFLS-----KVSTE---------IPAS 282
RP A+ E P P + ++P P LS K + E +P +
Sbjct: 650 RPRAAASNEPK--PAVPPSSEKKKHKSSLPAPSKALSGPEPAKDNVEDRTPEHFALVPLT 707
Query: 283 EPDGP----SVGRAKG--------QDA-------PLEFT---FHVEITPNVQKEQAHSEE 320
E GP S R G +D+ PL T + TP Q
Sbjct: 708 ESQGPPHSGSGSRTSGCRQAVVVQEDSRKDRLPLPLRDTKLLSPLRDTPPPQSLMVKITL 767
Query: 321 HLGRAAFPGAPGEGP-----EARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLK 375
L + P PG+G E + P G+ S + A +G+ K
Sbjct: 768 DL-LSRIPQPPGKGSRQRKAEDKQPPAGKKHSSEKRSSDSSSKLAKKRKGEAERDCDNKK 826
Query: 376 ARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV---- 431
R+ + K + S K S+++ ++ P P S +P+ PA+
Sbjct: 827 IRLEKEIKSQSSSSSSSHKESSKTKPSRPSSQSSKKEMLPPPPVSSSSQKPAKPALKRSR 886
Query: 432 -----CPEPPSSPKHVSSVTS-RTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANA 485
C + P PK SS S SS K+ +++G ++ KG +
Sbjct: 887 READTCGQDP--PKSASSTKSNHKDSSIPKQRRVEGKGSRSS---------SEHKGSSGD 935
Query: 486 TRIPAKTPPAPKTPPSSGEPPKSGDR 511
T P P P G+P D+
Sbjct: 936 TANPFPVPSLPNGNSKPGKPQVKFDK 961
Score = 33.5 bits (75), Expect = 0.75
Identities = 65/271 (23%), Positives = 89/271 (32%), Gaps = 59/271 (21%)
Query: 318 SEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEP----------SEKQPAAAPRGKP 367
SE LG+ +P P +G S + P S A PR +P
Sbjct: 83 SENRLGKPKYPLIPDKGSSIPSSSFHTSVHHQSIHTPASGPLSVGNISHNPKMAQPRTEP 142
Query: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRP-----CLSPKHPTPGSS-D 421
+ P L A+ + D+ + SS +R C S P
Sbjct: 143 M---PSLHAKSCGPPDSQHLTQDRLGQEGFGSSHHKKGDRRADGDHCASVTDSAPERELS 199
Query: 422 PLIQPSSPAVCPEPPSSPKHVSSVT-SRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQK 480
PLI SP PP SP H + T RT S K+ G+ +K P +P
Sbjct: 200 PLISLPSPV----PPLSPIHSNQQTLPRTQGSS----KVHGSSNNSKGYCP-AKSPKDLA 250
Query: 481 GQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREP 540
+ + P + AP PPS PP PSLP+
Sbjct: 251 VKVHDKETPQDSLVAPAQPPSQTFPP-----------------------PSLPS------ 281
Query: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLK 571
K VA+ + P + Q AP P+LK
Sbjct: 282 KSVAMQQKPTAYVRPMDGQDQ-APSESPELK 311
>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
Length = 1838
Score = 72.8 bits (177), Expect = 1e-12
Identities = 128/528 (24%), Positives = 169/528 (32%), Gaps = 100/528 (18%)
Query: 70 PTAEDVTAPLVDEGAPGKQA----AAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQE 125
P + P ++GAPG++ A + + P G +G P ED G + +
Sbjct: 1107 PGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGPVG--PPGEDGDKGEIGEP 1164
Query: 126 PESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAP 185
+ G +G E GPPG P GP+ QP +G + G R
Sbjct: 1165 GQKGSKGDKG---EQGPPG---------------PTGPQGPIGQPGPSGADGEPGPRG-- 1204
Query: 186 ELLKHQLLGDLHQEGP-----PLKGAGGKERPGSKEEVDEDRDVDESSPQDSP----PSK 236
+ L G EGP P G + PG E E DV + P P PS
Sbjct: 1205 ---QQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRGPSG 1261
Query: 237 ASPAQDGRPPQTAAREATSI-----------PGFPAEGAIPLPVDFLSKVSTEIPASEPD 285
A A + P ++ PG P EG P P + P+
Sbjct: 1262 APGADGPQGPPGGIGNPGAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESGPSGAAG 1321
Query: 286 GPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGED 345
P G D P + G FPG PG P GP+ G+D
Sbjct: 1322 PPGPKGPPGDDGP--------------------KGSPGPVGFPGDPGP-PGEPGPA-GQD 1359
Query: 346 TKEADLPEPSE--KQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSA-- 401
D + E + + P G+P P K + +K AK
Sbjct: 1360 GPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPP 1419
Query: 402 -KTLKNRPCLSPKHPTP----GSSDPLIQ---PSSPAVCPEPPSSPKHVSSVTSRTGSSG 453
KT P +P P P G P+ + P SP P+ P P + G SG
Sbjct: 1420 GKTGPIGPQGAPGKPGPDGLRGIPGPVGEQGLPGSPG--PDGPPGPMGPPGLPGLKGDSG 1477
Query: 454 AKEMK-------LKGADGKTKIATPRGAAPP----GQKGQANATRIPAKTPPAPKTPPSS 502
K K L G G+ RG P G KG+ T P P PP
Sbjct: 1478 PKGEKGHPGLIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITG--PSGPIGPPGPPGL 1535
Query: 503 GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR--EPKKVAVVRT 548
PP G S P P P P PP +P + RT
Sbjct: 1536 PGPPGPKGAKGSSGPTGPKGEAGHPGPPGPPGPPGEVIQPLPIQASRT 1583
Score = 57.8 bits (138), Expect = 4e-08
Identities = 134/558 (24%), Positives = 164/558 (29%), Gaps = 105/558 (18%)
Query: 28 GYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGK 87
G H Q G+T K P P G + P ET P+ + G PG
Sbjct: 973 GLPGHPGQRGETGFQGKTGPPGPPGVVGPQGPTGETG-------------PMGERGHPGP 1019
Query: 88 QAA----AQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLREPG 141
P EGT + G P + G G V G G
Sbjct: 1020 PGPPGEQGLPGLAGKEGTKGDPGPAG-LPGKDGPPGLRGFPGDRGLPGPVGALGLKGNEG 1078
Query: 142 PPGLSHQLMSGMPG--APLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQE 199
PPG +G PG P GP +P GP G + AP G+ +
Sbjct: 1079 PPGPPGP--AGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAP--------GEKGPQ 1128
Query: 200 GPP----LKGAGGKERP-GSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREAT 254
GP L+G G P G ED D E SK + G P T +
Sbjct: 1129 GPAGRDGLQGPVGLPGPAGPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPI 1188
Query: 255 SIPGFPAEGAIPLP---VDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNV 311
PG P P + E P P P +G P P
Sbjct: 1189 GQPGPSGADGEPGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGP----------PGE 1238
Query: 312 QKEQAHSEEHLGRAAFPGAPG----------EGPEARGPSLGEDTKEADLPEPSEK-QPA 360
+ E +G+ PG PG +GP+ +G + EP E +P
Sbjct: 1239 KGETG----DVGQMGPPGPPGPRGPSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEPG 1294
Query: 361 AAPRGKPVSRVPQLKARMVSKSKDGT--GSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP- 417
G P P K K + G + K P P P P
Sbjct: 1295 LPGEGGP----PGPKGERGEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPP 1350
Query: 418 ---------------GSSDPLIQPSSPAVCPEPPSS-------PKHVSSVTSRTGSSGAK 455
G Q SP EP S P + R G GAK
Sbjct: 1351 GEPGPAGQDGPPGDKGDDGEPGQTGSPGPTGEPGPSGPPGKRGPPGPAGPEGRQGEKGAK 1410
Query: 456 -EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT-------PPAPKTPPSSGEPPK 507
E L+G GKT P+GA PG+ G IP P P PP PP
Sbjct: 1411 GEAGLEGPPGKTGPIGPQGA--PGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPG 1468
Query: 508 SGDRSGYSSP-GSPGTPG 524
G S P G G PG
Sbjct: 1469 LPGLKGDSGPKGEKGHPG 1486
Score = 54.3 bits (129), Expect = 4e-07
Identities = 126/492 (25%), Positives = 165/492 (33%), Gaps = 99/492 (20%)
Query: 124 QEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRH 183
Q G V +G EPGPPG G PGA LP GP+ A P GP
Sbjct: 704 QPGPKGNVGPQG---EPGPPG-----QQGNPGAQGLP-GPQGAIGPPGEKGP-------- 746
Query: 184 APELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDG 243
L K L G +GPP G GKE P E P P + DG
Sbjct: 747 ---LGKPGLPGMPGADGPP--GHPGKEGPPG--EKGGQGPPGPQGPIGYPGPRGVKGADG 799
Query: 244 RPPQTAAREATSIPGFPA-EGAIPLPVDFLSKVSTEIPASE--PDGPSV-GRAKGQDAPL 299
+ GFP +G + + D ++ P E P+GP G G PL
Sbjct: 800 IRGLKGTKGEKGEDGFPGFKGDMGIKGD-RGEIGPPGPRGEDGPEGPKGRGGPNGDPGPL 858
Query: 300 -----EFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE----------GPEA-RGPS-- 341
+ V P Q + +G FPGA GE GP RGP+
Sbjct: 859 GPPGEKGKLGVPGLPGYPGRQG-PKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGP 917
Query: 342 LGEDTKEADLPEPSEKQPAAA--PRGKPVSRVPQ----------LKARMVSKSKDGT-GS 388
GE +P K + P G P R P K KDG G
Sbjct: 918 RGERGPRGITGKPGPKGNSGGDGPAGPPGERGPNGPQGPTGFPGPKGPPGPPGKDGLPGH 977
Query: 389 DDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSR 448
++ +T + + P+ PT G + P+ + P P P + + + +
Sbjct: 978 PGQRGETGFQGKTGPPGPPGVVGPQGPT-GETGPMGERGHPG--PPGPPGEQGLPGLAGK 1034
Query: 449 TGSSGAK-EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT----------PPAPK 497
G+ G L G DG PPG +G +P PP P
Sbjct: 1035 EGTKGDPGPAGLPGKDG-----------PPGLRGFPGDRGLPGPVGALGLKGNEGPPGPP 1083
Query: 498 TPPSS-GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSA 556
P S GE +G PG PG G PP +K A P+ P +
Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRPGPQG----------PPGPAGEKGAPGEKGPQGP-AG 1132
Query: 557 KSRLQTAPVPMP 568
+ LQ PV +P
Sbjct: 1133 RDGLQ-GPVGLP 1143
Score = 48.1 bits (113), Expect = 3e-05
Identities = 123/549 (22%), Positives = 168/549 (30%), Gaps = 104/549 (18%)
Query: 29 YTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQ 88
Y D EG+T + P + E+ G E + +K A T + +E P
Sbjct: 262 YYTEGDGEGETYY------YEYPYYEDPEDLGKEPTPSKKPVEAAKETTEVPEELTPTPT 315
Query: 89 AAAQPHTEIPEGTTAEE-AGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLR--EPGPPGL 145
AA P E EG EE GIGD + E + T P EG +P PG
Sbjct: 316 EAA-PMPETSEGAGKEEDVGIGDYDYVPSE--DYYTPSPYDDLTYGEGEENPDQPTDPGA 372
Query: 146 SHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLK----------HQLLGD 195
++ + P G G +D EG E ++ +
Sbjct: 373 GAEIPTSTADT-----SNSSNPAPPPGEGADDLEG-EFTEETIRNLDENYYDPYYDPTSS 426
Query: 196 LHQEGPPL--------KGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQ 247
+ GP + +G GG G K + E ++ + PP PA PP
Sbjct: 427 PSEIGPGMPANQDTIYEGIGGPR--GEKGQKGEPAIIEPGMLIEGPPGPEGPAGLPGPPG 484
Query: 248 TAA----------REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDA 297
T R PG P +P P + + G G
Sbjct: 485 TMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLPFRFGG--------GGDAGSKG 536
Query: 298 PLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEPSE 356
P+ + +Q+ + G G PG GP G GE + P
Sbjct: 537 PMVSAQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPG-DVGPQGPRG 595
Query: 357 KQPAAAPRGKPVSRVPQLKARMVSKSKDG----TGSDDKKAKTSTRSSAKTLKNRPCLSP 412
Q P GKP R R S G TG + +R P
Sbjct: 596 VQGPPGPAGKPGRR-----GRAGSDGARGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGP 650
Query: 413 KHPT-----------PGSSDPLIQPSSPA----VCPEPPSSPKHVSSVTSRTGSSGAKEM 457
P G P P P + P+ P P VT G G K
Sbjct: 651 SGPPGPPGDDGERGDDGEVGPRGLPGEPGPRGLLGPKGPPGPPGPPGVTGMDGQPGPK-- 708
Query: 458 KLKGADGKTKIATPRGA-APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS 516
G G P+G PPGQ+G A +P P + PP G++
Sbjct: 709 ---GNVG------PQGEPGPPGQQGNPGAQGLPG--------PQGAIGPP--GEKGPLGK 749
Query: 517 PGSPGTPGS 525
PG PG PG+
Sbjct: 750 PGLPGMPGA 758
Score = 36.2 bits (82), Expect = 0.12
Identities = 70/308 (22%), Positives = 100/308 (32%), Gaps = 74/308 (24%)
Query: 231 DSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVG 290
+ P + P AA+E T +P E P P + T A + + +G
Sbjct: 281 EDPEDLGKEPTPSKKPVEAAKETTEVP----EELTPTPTEAAPMPETSEGAGKEEDVGIG 336
Query: 291 RAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEAD 350
+ +T +P EE+ + PGA E P T AD
Sbjct: 337 DYDYVPSEDYYT----PSPYDDLTYGEGEENPDQPTDPGAGAEIP----------TSTAD 382
Query: 351 LPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCL 410
S PA P G G+DD + + + +T++N L
Sbjct: 383 TSNSSN--PAPPP---------------------GEGADDLEGEFTE----ETIRN---L 412
Query: 411 SPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
+ P DP PS P P + ++ G + KG G+ I
Sbjct: 413 DENYYDP-YYDPTSSPSEIG-----PGMPANQDTIYEGIGGPRGE----KGQKGEPAIIE 462
Query: 471 PRGA--APPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSR 528
P PPG +G PA P P T +G+ G+R PG PG G
Sbjct: 463 PGMLIEGPPGPEG-------PAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADG---- 511
Query: 529 TPSLPTPP 536
LP PP
Sbjct: 512 ---LPGPP 516
Score = 36.2 bits (82), Expect = 0.12
Identities = 93/448 (20%), Positives = 137/448 (30%), Gaps = 70/448 (15%)
Query: 124 QEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRH 183
QE ++ ++Q+ L GP G ++G PG P+ P G +P GP+ G +
Sbjct: 542 QESQAQAILQQARLALRGPAGPMG--LTGRPG-PVGPPGSGGLKGEPGDVGPQGPRGVQG 598
Query: 184 APELL-KHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASP--- 239
P K G +G +G G+ P D + P + P
Sbjct: 599 PPGPAGKPGRRGRAGSDGA--RGMPGQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPGP 656
Query: 240 -AQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAP 298
DG +PG P + P P P P V GQ P
Sbjct: 657 PGDDGERGDDGEVGPRGLPGEPGPRGLLGPKG---------PPGPPGPPGVTGMDGQPGP 707
Query: 299 LEFTFHVEITPNVQKEQAH-----------------SEEHLGRAAFPGAPG-EGPEARGP 340
+ + P +Q + + LG+ PG PG +GP
Sbjct: 708 -KGNVGPQGEPGPPGQQGNPGAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPG 766
Query: 341 SLGEDTKEADLPEPSEKQPAA--APRG-KPVSRVPQLKARMVSKSKDGTGSDDKKAKTST 397
G ++ P + P PRG K + LK K +DG
Sbjct: 767 KEGPPGEKGGQGPPGPQGPIGYPGPRGVKGADGIRGLKGTKGEKGEDGF--------PGF 818
Query: 398 RSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAK-E 456
+ +R + P P P D PE P + G G K +
Sbjct: 819 KGDMGIKGDRGEIGP--PGPRGEDG----------PEGPKGRGGPNGDPGPLGPPGEKGK 866
Query: 457 MKLKGADGKTKIATPRGAAP----PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRS 512
+ + G G P+G+ PG G+ P K P + P+ G+R
Sbjct: 867 LGVPGLPGYPGRQGPKGSIGFPGFPGANGEKGGRGTPGKPGPRGQRGPTGPR----GERG 922
Query: 513 GYSSPGSPGTPGSRSRTPSLPTPPTREP 540
G PG G+ P R P
Sbjct: 923 PRGITGKPGPKGNSGGDGPAGPPGERGP 950
>gi|112821681 G protein-regulated inducer of neurite outgrowth 1
[Homo sapiens]
Length = 1008
Score = 72.0 bits (175), Expect = 2e-12
Identities = 132/560 (23%), Positives = 208/560 (37%), Gaps = 95/560 (16%)
Query: 51 PTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQ---AAAQPHTEIPEGTTAEEAG 107
P ++ S +D S + +++ VD + GK + +P E+ AE
Sbjct: 387 PVSGHTDTTASAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKP--ELLSPGQAERVS 444
Query: 108 IGD----TPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP--LLPE 161
+G +P ED + +G P G ++ + SG PG P L
Sbjct: 445 VGKAGTVSPGKEDPVSSRREDPISAGSRKTSSEKVNPESSGKTNPVSSG-PGDPRSLGTA 503
Query: 162 GPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDED 221
GP PS E GG+ P L + G L G A GK P +
Sbjct: 504 GP------PSAVKAEPATGGKGDP--LSSEKAG-LVASGKAAPTASGKAEPLA------- 547
Query: 222 RDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPA 281
V + P + A P+ G+ + + S PG +P+P + VS
Sbjct: 548 --VGKEDPVSKGKADAGPS--GQGDSVSIGKVVSTPG----KTVPVPSGKVDPVSLGKAE 599
Query: 282 SEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPS 341
+ P+G K PLE V T + ++ G A PG+ A
Sbjct: 600 AIPEG------KVGSLPLEKGSPVTTTKADPRASGKAQPQSGGKAETKLPGQEGAAAPGE 653
Query: 342 LGEDTKEADLPEPSEK---------QPAAAPRGKPVS--RVPQLKARMVSKSKDGTGSDD 390
G + + P+ SEK +P A+ +G+PVS + +R G
Sbjct: 654 AGAVCLKKETPQASEKVDPGSCRKAEPLASGKGEPVSLGKADSAPSRKTESPSLGKVVPL 713
Query: 391 KKAKTSTRSSAKTLKNRPCLSPKHPTPG-SSDPLIQPSSPAVCPEPPSSPKHVSSVTSRT 449
KT SS++ L + S + P S+ ++P + EP SS +
Sbjct: 714 SLEKTKPSSSSRQLDRKALGSARSPEGARGSEGRVEPKA-----EPVSS--------TEA 760
Query: 450 GSSGAKEMKLKGADGKTKIATPRGAAPP-GQKGQANATRIPAKTPPAPKTPPSSGEPPKS 508
S G K+++ GA+ + P AAPP G + + N T+ P+ AP PP ++
Sbjct: 761 SSLGQKDLEAAGAE---RSPCPEAAAPPPGPRTRDNFTKAPSWEASAPP-PPREDAGTQA 816
Query: 509 GDRSGYS---SPGSP-----GTPGSRSRTPSLPTPPTREPKKVAV---------VRTPPK 551
G ++ S SP SP G+ S P P+PP+R + V V T P
Sbjct: 817 GAQACVSVAVSPMSPQDGAGGSAFSFQAAPRAPSPPSRRDAGLQVSLGAAETRSVATGPM 876
Query: 552 SPSSAKSRLQTAPVPMPDLK 571
+P +A AP P+++
Sbjct: 877 TPQAA------APPAFPEVR 890
Score = 44.7 bits (104), Expect = 3e-04
Identities = 128/568 (22%), Positives = 188/568 (33%), Gaps = 89/568 (15%)
Query: 17 TYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPT-AEDV 75
TY + RK+ G D + P G E P S K PT AE V
Sbjct: 225 TYTVSPRKEDPGSLRKVDPVSSDKVDPVFPRKEEPRYSGKEHP---VSSEKVAPTSAEKV 281
Query: 76 TAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEG 135
L + PG A P S++ + G T+ GK++
Sbjct: 282 DLVLSGKRDPGPSGKADPMP---------------LESMDSASTGK-TEPGLLGKLI--- 322
Query: 136 FLREPGPPGLSHQLMSGM--PGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLL 193
PG G + + SG PG+ + P+ G +T ++
Sbjct: 323 ----PGSSGKNGPVSSGTGAPGSLGRLDPTCLGMADPASVGNVETVPATKEDSRFLGKMD 378
Query: 194 GDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPP---SKASPAQDGRPPQTAA 250
EG P+ G +K ++ ++VD S P K P G+P +
Sbjct: 379 PASSGEGRPVSGHTDTTA-SAKTDLTSLKNVDPMSSGKVDPVSLGKMDPMCSGKPELLSP 437
Query: 251 REATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITP- 309
+A + + K T P E D S R A T ++ P
Sbjct: 438 GQAERVS--------------VGKAGTVSPGKE-DPVSSRREDPISAGSRKTSSEKVNPE 482
Query: 310 -----NVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPR 364
N LG A P A P G +++A L + P A+ +
Sbjct: 483 SSGKTNPVSSGPGDPRSLGTAGPPSAVKAEPATGGKGDPLSSEKAGLVASGKAAPTASGK 542
Query: 365 GKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424
+P++ K VSK K G + S T P + P+ G DP+
Sbjct: 543 AEPLAVG---KEDPVSKGKADAGPSGQGDSVSIGKVVST----PGKTVPVPS-GKVDPVS 594
Query: 425 QPSSPAVCPE------PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPG 478
+ A+ PE P V++ + +SG K G +TK+ GAA PG
Sbjct: 595 LGKAEAI-PEGKVGSLPLEKGSPVTTTKADPRASG-KAQPQSGGKAETKLPGQEGAAAPG 652
Query: 479 QKGQANATRIPAKTPPA-PKTPPSS---GEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 534
+ G A + +TP A K P S EP SG G P S + S P+
Sbjct: 653 EAG---AVCLKKETPQASEKVDPGSCRKAEPLASG----------KGEPVSLGKADSAPS 699
Query: 535 PPTREPK--KVAVVRTPPKSPSSAKSRL 560
T P KV + PSS+ +L
Sbjct: 700 RKTESPSLGKVVPLSLEKTKPSSSSRQL 727
Score = 35.0 bits (79), Expect = 0.26
Identities = 85/404 (21%), Positives = 141/404 (34%), Gaps = 55/404 (13%)
Query: 202 PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPA 261
P G+ G ++ + + P+ +P R P A A+ G
Sbjct: 30 PQDGSLGAGSSAMRDYCPSQQKASPAPPRHTPDQSPGMESRHRSPSGAGEGASCSDGPRG 89
Query: 262 EGAIPLPVDFLSKVSTEIPASEPDGPSV-----GRAKGQDAPLEFTFHVEITPNVQKEQA 316
A P P F + S E G S+ G+ P+ +V+ E
Sbjct: 90 SLACPSPTCFSPQESPSKETLEAHGASISGTPEATTSGKPEPVS---------SVKTEPK 140
Query: 317 HSEEH----LGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVS--R 370
S++ L + F + + G +++AD + +P +G PV+ R
Sbjct: 141 SSDDRNPMFLEKMDFKSSKQADSTSIGKEDPGSSRKADPMFTGKAEPEILGKGDPVAPGR 200
Query: 371 VPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPA 430
+ + R K+ GS K S+KT +SP+ PGS + SS
Sbjct: 201 MDPMTVR-----KEDLGS---LGKVDPLCSSKTY----TVSPRKEDPGSLRKVDPVSSDK 248
Query: 431 VCP------EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQAN 484
V P EP S K + + + A+++ L G PG G+A+
Sbjct: 249 VDPVFPRKEEPRYSGKEHPVSSEKVAPTSAEKVDL----------VLSGKRDPGPSGKAD 298
Query: 485 ATRIPA-KTPPAPKTPPS--SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT-PPTREP 540
+ + + KT P P S ++G S G+ G PGS R PT +P
Sbjct: 299 PMPLESMDSASTGKTEPGLLGKLIPGSSGKNGPVSSGT-GAPGSLGRLD--PTCLGMADP 355
Query: 541 KKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSKIGSTENLK 584
V V T P + ++ + P + + V +T + K
Sbjct: 356 ASVGNVETVPATKEDSRFLGKMDPASSGEGRPVSGHTDTTASAK 399
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 71.6 bits (174), Expect = 2e-12
Identities = 123/552 (22%), Positives = 214/552 (38%), Gaps = 53/552 (9%)
Query: 23 RKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDE 82
++D G ++Q E D +KE ++ + S E + + + + +++P++D
Sbjct: 1352 KEDLNGPFLNQ-LETDPSLDMKEQSTRS-SGHSSSELSPDAVEKAGMSSNQSISSPVLDA 1409
Query: 83 --GAPGKQAAAQPHT-EIPEG---TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGF 136
P ++ ++ + E+ +G T + + G +P L D +G ++ SG G
Sbjct: 1410 VPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRD-GSGTPSRHSLSGS--SPGM 1466
Query: 137 LREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDL 196
P P P LP+ PR +R PS + P+ + +
Sbjct: 1467 KDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSP---ELNNKCLTPQRERSGSESSV 1523
Query: 197 HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI 256
Q+ G + R GS +E+D +SPQ+ S +SP + A+ T +
Sbjct: 1524 DQKTVARTPLGQRSRSGSSQELDVK---PSASPQERSESDSSP-------DSKAKTRTPL 1573
Query: 257 PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA 316
G+ P VD S++S P G S + +D P + + + +A
Sbjct: 1574 RQRSRSGSSP-EVDSKSRLS---PRRSRSGSS---PEVKDKPRAAPRAQSGSDSSPEPKA 1626
Query: 317 HSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKA 376
+ L R + G+ +G RGPS + PE K A RG S P+ K+
Sbjct: 1627 PAPRALPRRSRSGSSSKG---RGPSPEGSSSTESSPEHPPKSRTAR-RGSRSSPEPKTKS 1682
Query: 377 RMVSKSKDGTGSDD--KKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAV-CP 433
R + + S + +KA+ S RS + + P S P SP+V P
Sbjct: 1683 RTPPRRRSSRSSPELTRKARLSRRSRS---------ASSSPETRSRTPPRHRRSPSVSSP 1733
Query: 434 EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTP 493
EP S + R S+ + K G++ PRG + + TR +
Sbjct: 1734 EPAEK----SRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRD 1789
Query: 494 PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPS-LPTPPTREPKKVAVVRTPPKS 552
+ + +S +S RS + G+ G SR+P+ + T ++ RTPP S
Sbjct: 1790 RSGSSQSTSRRRQRSRSRSRVTRRRRGGS-GYHSRSPARQESSRTSSRRRRGRSRTPPTS 1848
Query: 553 PSSAKSRLQTAP 564
++SR AP
Sbjct: 1849 RKRSRSRTSPAP 1860
Score = 65.5 bits (158), Expect = 2e-10
Identities = 145/592 (24%), Positives = 219/592 (36%), Gaps = 117/592 (19%)
Query: 38 DTDAGLKESPLQTP-TEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTE 96
D+++ L +S L+T +++ P E + A S P +D +P + P +
Sbjct: 1149 DSNSLLGQSRLETAESKEKMALPPQEDATA-SPPRQKDKFSPFPVQDRPESSLVFKDTLR 1207
Query: 97 IPEGTTAEEAGIGDTPSLEDEAAGHVT--QEPESGKVVQEGFLREPGPPGLSH------- 147
P E +G G +P +++ + T Q+ E +VV++ EP LSH
Sbjct: 1208 TPP---RERSGAGSSPETKEQNSALPTSSQDEELMEVVEKS--EEPAGQILSHLSSELKE 1262
Query: 148 QLMSGMPGAPLLPEGPR--------------EATRQPSGTGPEDTEGGRHAPELLKHQLL 193
S +P + E P EA PS + GG H K
Sbjct: 1263 MSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMAS---SWGGPHFSPEHKELSN 1319
Query: 194 GDLHQE--GPPLK-----GAGGKERPGSKEEVDEDRDVDESSPQDSPPS----KASPAQD 242
L + G PL+ G + G EV ED + + ++ PS + S
Sbjct: 1320 SPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSS 1379
Query: 243 GRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFT 302
G + +A G + +I PV L V P PS R+ +P E
Sbjct: 1380 GHSSSELSPDAVEKAGMSSNQSISSPV--LDAV--------PRTPSRERSSSASSP-EMK 1428
Query: 303 FHVEITPNVQKEQAHSEEHLGRAAFPG-------APGEGPEARGPSLGEDTKEADLPEPS 355
+ TP+ + S + P +PG R PS G ++ PEP
Sbjct: 1429 DGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSS-PEPK 1487
Query: 356 EKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSD---DKKA-------KTSTRSSAKTLK 405
PR + S P+L + ++ ++ +GS+ D+K + S S++ L
Sbjct: 1488 ALPQTPRPRSRSPSS-PELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELD 1546
Query: 406 NRPCLSPKHPTPGSSDP---------LIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKE 456
+P SP+ + S P L Q S PE S + +S SR+GSS E
Sbjct: 1547 VKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSR-LSPRRSRSGSS--PE 1603
Query: 457 MKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSS 516
+K K PR AAP Q G ++ P PK P P +S RSG SS
Sbjct: 1604 VKDK----------PR-AAPRAQSGSDSS--------PEPKAPAPRALPRRS--RSGSSS 1642
Query: 517 PGSPGTPGSRSRTPSLPTPPTRE----------PKKVAVVRTPPKSPSSAKS 558
G +P S T S P P + P+ RTPP+ SS S
Sbjct: 1643 KGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSS 1694
Score = 58.9 bits (141), Expect = 2e-08
Identities = 77/293 (26%), Positives = 109/293 (37%), Gaps = 51/293 (17%)
Query: 347 KEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKD-GTGSDDKKAKTSTRSSAKTLK 405
+EA P P +P + R SR P K + K KD G S+ + + S+K K
Sbjct: 158 REAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKK 217
Query: 406 NRPCLSPK-----HPTPGS---SDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEM 457
+R K PTP S S + S + P P S H S+ SS
Sbjct: 218 HRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS 277
Query: 458 KLKGADGKTKIATPRGAAP---PGQKGQANA---------TRIPAKTPPAPKTPPSSGE- 504
+ + A KT G +P G++G+ +A T+ P+ A K P S E
Sbjct: 278 RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337
Query: 505 ------------PPKSGDRSGYS-SPGSP---------GTPGSRSRTPSLPTPPTREPKK 542
P S +RS P +P G+P + TP L P P +
Sbjct: 338 KDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTP-LSQEPVNPPSE 396
Query: 543 VAVV--RTPPKSPS---SAKSRLQTAPVPMPDLKNVKSKIGSTENLKHQPGGG 590
+ R+PPKSP + S + P P P K + S E+ K P G
Sbjct: 397 ASPTRDRSPPKSPEKLPQSSSSESSPPSPQP-TKVSRHASSSPESPKPAPAPG 448
Score = 55.1 bits (131), Expect = 2e-07
Identities = 121/616 (19%), Positives = 199/616 (32%), Gaps = 104/616 (16%)
Query: 45 ESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAE 104
E P TP +E G +TP +++ P + ++ + ++P+ +++E
Sbjct: 362 EPPAPTPLL--AERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSE 419
Query: 105 EAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPR 164
+ P+ + + H + PES K P P SH+ +S P + G
Sbjct: 420 SSPPSPQPT---KVSRHASSSPESPK---------PAPAPGSHREISSSPTSKNRSHGRA 467
Query: 165 EATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDV 224
+ + S T P G +P K G P +G P + R
Sbjct: 468 KRDKSHSHT-PSRRMGRSRSPATAKR---GRSRSRTPTKRGHSRSRSPQWRRSRSAQRWG 523
Query: 225 DESSPQDSPPSKA-----------------------------SPAQDGRP-PQTAAREAT 254
SPQ S++ SPA GR +T AR
Sbjct: 524 RSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGR 583
Query: 255 SIPGFPAEGAIPLPVDFLSKVSTEIPA--------------SEPDGPSVGRAKGQDAPLE 300
S PA + + PA S P R++ +
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARR 643
Query: 301 FTFHVEITP---NVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEK 357
TP + + + R+ P +R P+ ++ +
Sbjct: 644 SGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSR 703
Query: 358 QPAAAPRGKPVSRVPQLKARMVS----KSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPK 413
+ RG+ SR PQ + R S K+K T ++ +S + +R S
Sbjct: 704 SRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLS 763
Query: 414 HPTPGSSDPL-----IQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKI 468
P + L + SSP PK S R SG+ + K K +
Sbjct: 764 SPRSKAKSRLSLRRSLSGSSPC--------PKQKSQTPPRRSRSGSSQPKAKSRTPPRR- 814
Query: 469 ATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR-- 526
+ + PP QK + + + + + P PK SG PP+ G + + TP R
Sbjct: 815 SRSSSSPPPKQKSKTPSRQSHSSSSPHPKV--KSGTPPRQGSITSPQANEQSVTPQRRSC 872
Query: 527 ----------SRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVKSK 576
SRTPS + P +V P +SPS + S P P +K + S
Sbjct: 873 FESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSS-------PQPKVKAIISP 925
Query: 577 IGSTENLKHQPGGGKV 592
+ + P +V
Sbjct: 926 RQRSHSGSSSPSPSRV 941
Score = 52.8 bits (125), Expect = 1e-06
Identities = 95/426 (22%), Positives = 157/426 (36%), Gaps = 69/426 (16%)
Query: 160 PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP------PLKGA--GGKER 211
P P AT+QPS ED + + + + GP PL GG +
Sbjct: 321 PSSPETATKQPSSPY-EDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQ 379
Query: 212 PGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDF 271
P + + ++ +PPS+ASP +D PP++ + S +E + P P
Sbjct: 380 PLATTPLSQE--------PVNPPSEASPTRDRSPPKSPEKLPQS---SSSESSPPSPQP- 427
Query: 272 LSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPN-VQKEQAHSEEHLGRAAFPGA 330
+KVS +S P+ P A G H EI+ + K ++H GRA +
Sbjct: 428 -TKVSRH-ASSSPESPKPAPAPGS--------HREISSSPTSKNRSH-----GRAKRDKS 472
Query: 331 PGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDD 390
P R +G + PA A RG+ SR P + S+S S
Sbjct: 473 HSHTPSRR---MGR-----------SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRS 518
Query: 391 K----KAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVT 446
++++ R RP S T + P + + S
Sbjct: 519 AQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTP 578
Query: 447 SRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTP----PSS 502
+R G S ++ + + +T + P ++G++ +R PA+ ++P S
Sbjct: 579 ARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSR-SRTPARRRSRTRSPVRRRSRS 637
Query: 503 GEPPKSGDRSGYSSPGSPG-----TPG----SRSRTPSLPTPPTREPKKVAVVRTPPKSP 553
P + RS +P G TP SRSRTP+ + +R R+ ++P
Sbjct: 638 RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTP 697
Query: 554 SSAKSR 559
+SR
Sbjct: 698 RRGRSR 703
Score = 47.0 bits (110), Expect = 7e-05
Identities = 93/446 (20%), Positives = 155/446 (34%), Gaps = 70/446 (15%)
Query: 154 PGAPLLPEGPREAT----RQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAG-- 207
P + P+ P A R T P + G R A L L + P L GA
Sbjct: 2324 PSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSA--RMAPALSGANLT 2381
Query: 208 GKERPGSKEEVDEDR------DVDESSPQDSPPSKASPAQDGRP-PQTAAREATS---IP 257
P S E R D S S PS++ + P P + +A S +P
Sbjct: 2382 SPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLP 2441
Query: 258 GFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAH 317
+ P+P F + I + P S + G V +
Sbjct: 2442 PAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGA---------------VATTTSS 2486
Query: 318 SEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKAR 377
+ +H G + P APG P + +GE +PS + + S +
Sbjct: 2487 AGDHNGMLSVP-APGV-PHS---DVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSS 2541
Query: 378 MVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKH---PTPGSSDPLIQPSSPAVCPE 434
S S + S +S+ S +L +P ++ K PTP + + + P P
Sbjct: 2542 SSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPE--PT 2599
Query: 435 PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPP 494
P + SS +S + SS + + + ++ ++ ++++ PAK P
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP 2656
Query: 495 APKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPS 554
P+S + P G+R RSR+P P R+ + ++
Sbjct: 2657 QALPKPASPKKPPPGER--------------RSRSPRKPIDSLRDSRSLSY--------- 2693
Query: 555 SAKSRLQTAPVPMP-DLKNVKSKIGS 579
S R + +P P P D ++ S+ GS
Sbjct: 2694 SPVERRRPSPQPSPRDQQSSSSERGS 2719
Score = 39.7 bits (91), Expect = 0.010
Identities = 77/349 (22%), Positives = 117/349 (33%), Gaps = 56/349 (16%)
Query: 201 PPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGFP 260
PP + G +P +K R SSP SK Q + + P P
Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTP--P 850
Query: 261 AEGAIPLPVDFLSKVSTEIPA---SEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAH 317
+G+I P V+ + + S PD R P + P V K
Sbjct: 851 RQGSITSPQANEQSVTPQRRSCFESSPDPELKSR-----TPSRHSCSGSSPPRV-KSSTP 904
Query: 318 SEEHLGRAAFPGAPGE---GPEARGPSLGEDTKEADLPEPSEKQPAAAP-RGKPVSRVPQ 373
+ R++ P + P R S + P PS P R + VS
Sbjct: 905 PRQSPSRSSSPQPKVKAIISPRQRSHS------GSSSPSPSRVTSRTTPRRSRSVSPCSN 958
Query: 374 LKARMVSK-SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVC 432
+++R++ + S G+ S D K K T P+ GS P P A
Sbjct: 959 VESRLLPRYSHSGSSSPDTKVKPET-------------PPRQSHSGSISP--YPKVKAQT 1003
Query: 433 PEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKI-ATPRGAAPPGQ----------KG 481
P PS +S S +K+ ++ G + A + + PPG+ KG
Sbjct: 1004 PPGPS----LSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKG 1059
Query: 482 QANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTP 530
Q+ + +P+ S E P +S S G SRS +P
Sbjct: 1060 QSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGG----RSRSSSP 1104
Score = 39.7 bits (91), Expect = 0.010
Identities = 84/366 (22%), Positives = 129/366 (35%), Gaps = 38/366 (10%)
Query: 232 SPPSKASP-AQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVG 290
SP + +P A + P+T A ++ G P + LS + P + + PS
Sbjct: 2272 SPRTAVAPSAVNLADPRTPTAPAVNLAG----ARTPAALAALSLTGSGTPPTAANYPSSS 2327
Query: 291 RAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEAR-GPSLGEDTKEA 349
R A + P A R A AP AR P+L A
Sbjct: 2328 RTPQAPASANL-----VGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSG----A 2378
Query: 350 DLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC 409
+L P + P +A P L R S++ S + S + + P
Sbjct: 2379 NLTSP--RVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPS 2436
Query: 410 LS--------PKHPTPGS----SDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEM 457
S P+ P P + S LI ++P + SS ++ +S +G +
Sbjct: 2437 QSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSV 2496
Query: 458 KLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP 517
G P A+ Q+ A A PAK + + SS S S SS
Sbjct: 2497 PAPGVPHSDVGEPP--ASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS-SSS 2553
Query: 518 GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKS-RLQTAPVPMPDLKNVKSK 576
S G+ S S SLP P +VA+ R P +P+ ++ R P P P + +S
Sbjct: 2554 SSSGSSSSDSEGSSLPVQP-----EVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSS 2608
Query: 577 IGSTEN 582
S+ +
Sbjct: 2609 SSSSSS 2614
Score = 38.1 bits (87), Expect = 0.031
Identities = 91/453 (20%), Positives = 147/453 (32%), Gaps = 86/453 (18%)
Query: 142 PPGLSHQLMSGMPGAPLLPE--GPREA----------TRQPSGTGPEDTEGGRHAPELLK 189
P ++ S P AP GPR A +R + P R AP L
Sbjct: 2318 PTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSG 2377
Query: 190 HQLLGDL----------HQEGPPLKGAGGKERPGS---KEEVDEDRDVDESSPQDSPPSK 236
L + PPL P S + + +R SS PS+
Sbjct: 2378 ANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ 2437
Query: 237 A--SPAQDG-RPPQTAA---------REATSIPGFPA--EGAIPLPVD-------FLSKV 275
+ PAQD R P +A + T + G + GA+ LS
Sbjct: 2438 SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVP 2497
Query: 276 STEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGP 335
+ +P S+ P Q + L + P ++ + S ++ +
Sbjct: 2498 APGVPHSDVGEPPASTGAQQPSAL-----AALQPAKERRSSSSSSSSSSSSSSSSSSSSS 2552
Query: 336 EARGPSLGEDTKEADLPEPSE------KQPAAAPR-----GKPVSRVPQLKARMVSKSKD 384
+ S D++ + LP E P AP+ G+P P + R S S
Sbjct: 2553 SSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSS 2612
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSS 444
+ S + +S+ SS+ + + S + SS +P P P+ P+SPK
Sbjct: 2613 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKP-GPQALPK-PASPK---- 2666
Query: 445 VTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGE 504
K G+ + +PR + ++ + + P+P+ P +
Sbjct: 2667 ---------------KPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQ 2711
Query: 505 PPKS--GDRSGYSSPGSPGTPGSRSRTPSLPTP 535
S G R G + R TPS P P
Sbjct: 2712 SSSSERGSRRGQRGDSRSPSHKRRRETPS-PRP 2743
Score = 37.7 bits (86), Expect = 0.040
Identities = 114/589 (19%), Positives = 196/589 (33%), Gaps = 80/589 (13%)
Query: 13 DHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTA 72
+ +G+ D+K + Q + L P +P E SE S S AK+
Sbjct: 1515 ERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER-SESDSSPDSKAKTR--- 1570
Query: 73 EDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVV 132
PL G + P + + + G +P ++D+ P +
Sbjct: 1571 ----TPLRQRSRSG----SSPEVDSKSRLSPRRSRSGSSPEVKDK--------PRAAPRA 1614
Query: 133 QEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREAT----RQPSGTGPEDTEGGRHAPELL 188
Q G P P P LP R + R PS G TE P
Sbjct: 1615 QSGSDSSPEPKA---------PAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKS 1665
Query: 189 KHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQT 248
+ G P K R S+ + R S + S + +SP R P
Sbjct: 1666 RTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLS--RRSRSASSSPETRSRTPPR 1723
Query: 249 AAREATSIPGFPAEGA--------IPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLE 300
R + PAE + P + P+ +P G R++ +
Sbjct: 1724 HRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTR 1783
Query: 301 FTFHVEITPNVQKEQAHSEEHLGRAAFPGAP--GEGPEARGPSLGEDTKEADL------- 351
T + + + Q + R+ G G +R P+ E ++ +
Sbjct: 1784 TTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSR 1843
Query: 352 --------------PEP---SEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAK 394
P P S + + A + SR P + R +S+ T S + +
Sbjct: 1844 TPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRR---RSRSRT-SPVSRRR 1899
Query: 395 TSTRSSAKTLKNRPCLSP--KHPTPGSSDPLIQPSSPAVCPEPPS-SPKHVSSVTSRTGS 451
+ +R+S ++R SP + + + P+ + S + P S VT R
Sbjct: 1900 SRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSR 1959
Query: 452 SGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDR 511
S + + + +T T R + + R ++T P + S P + R
Sbjct: 1960 SRTPPVTRRRSRSRTSPITRRRSR--SRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRR 2017
Query: 512 SGYSSPGSPGTPGSRSRTPSLPTPPTREPKKVAV-VRTPPKSPSSAKSR 559
S +P + SRSRTP LP +R +A+ R+ ++P +A+ +
Sbjct: 2018 SRSRTPPAIRRR-SRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGK 2065
Score = 33.1 bits (74), Expect = 0.98
Identities = 56/238 (23%), Positives = 89/238 (37%), Gaps = 42/238 (17%)
Query: 449 TGSSGAKEMKLK-------GADGKTKIATPRGAAPPG--QKGQANATRIPAKTPPAPKTP 499
T SSG +L G I++P A P + ++++ P P+TP
Sbjct: 1376 TRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTP 1435
Query: 500 PS---SGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPTPPTR-------EPKKVAVVRTP 549
SG P G R G +P GS +P P+R P+ A+ +TP
Sbjct: 1436 SRRSRSGSSP--GLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTP 1493
Query: 550 ---PKSPSSAK--------SRLQTAPVPMPDLKNV-------KSKIGSTENLKHQPGGGK 591
+SPSS + R ++ D K V +S+ GS++ L +P
Sbjct: 1494 RPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASP 1553
Query: 592 VQIINKKLDLSNVQSKCGSKDNIKHVPGGGSVQIVYKPVDLSKVTSKCGSLGNIHHKP 649
+ + S+ SK ++ ++ GS V LS S+ GS + KP
Sbjct: 1554 QE---RSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKP 1608
>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
sapiens]
Length = 1487
Score = 69.7 bits (169), Expect = 9e-12
Identities = 124/500 (24%), Positives = 161/500 (32%), Gaps = 111/500 (22%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLR 138
+ G PGK P P+G G TP L G+ + G+ G
Sbjct: 256 EAGKPGKAGERGPPG--PQGAR----GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 309
Query: 139 EPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
E G PG +G PG P GPR + TGP G R G+ Q
Sbjct: 310 ESGSPG-----ENGSPG----PMGPRGLPGERGRTGPAGAAGAR-----------GNDGQ 349
Query: 199 EGP--------PLKGAGGKERPGSKEEVD----------EDRDVDESSPQDSPPSKAS-- 238
GP P G G PG+K E + + +P P+ AS
Sbjct: 350 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 409
Query: 239 PAQDGRPPQTAAREATSI---PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQ 295
P DG P + A I PGFP P P + P + P + KG+
Sbjct: 410 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG---PKGQTGEPGIAGFKGE 466
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEP 354
P + G A GAPG G E + + GE + P
Sbjct: 467 QGP--------------------KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 506
Query: 355 SEK-----------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKT 403
E+ A P+G P R P A G D + A+
Sbjct: 507 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----GPKGANGDPGRPGEPGLPGARG 561
Query: 404 LKNRPC-------LSP-----KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGS 451
L RP + P + PG P P V P PK + + G
Sbjct: 562 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP--GPKGANGEPGKAGE 619
Query: 452 SGAKEMK----LKGADGKTKIATPRG-AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 506
G L G DG+T A P G A P G++G+ A P+ P P GE
Sbjct: 620 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPPGEGG 678
Query: 507 KSGDRSGYSSPGSPGTPGSR 526
K GD+ G+PG G R
Sbjct: 679 KPGDQGVPGEAGAPGLVGPR 698
Score = 63.9 bits (154), Expect = 5e-10
Identities = 128/561 (22%), Positives = 173/561 (30%), Gaps = 71/561 (12%)
Query: 71 TAEDVTAPLVDEGAPG--KQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA----GHVTQ 124
TA P +G PG K P+G E+ GD ++ A G +
Sbjct: 95 TASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGE 154
Query: 125 EPESGKVVQEGFLREPGPPGLSHQLMSGMPGA---------------PLLPEGPREATRQ 169
G G PGPPGL + M G P+ P GPR
Sbjct: 155 PGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGP 214
Query: 170 PSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSP 229
GP+ +G P + + G + GPP G +PG E + E P
Sbjct: 215 AGAPGPQGFQGNPGEPG--EPGVSGPMGPRGPP----GPPGKPGDDGEAGKPGKAGERGP 268
Query: 230 QDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP-S 288
++ P G P R + G E P V S E + P GP
Sbjct: 269 PGPQGARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAP-GVKGESGSPGENGSPGPMGPRG 327
Query: 289 VGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRA---AFPGAPGEGPE-----ARGP 340
+ +G+ P + Q A +G A FPGAPG E ARGP
Sbjct: 328 LPGERGRTGPAGAA--GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGP 385
Query: 341 SLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKAKTSTRS 399
G + P PA A +P K + G G + +
Sbjct: 386 E-GAQGPRGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444
Query: 400 SAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKL 459
+ P P + +P I P+ P G G
Sbjct: 445 AT---------GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK----- 490
Query: 460 KGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPA-PKTPPS----SGEPPKSGDRSGY 514
+GA G+ P G PPG++G P + A PK P SG G
Sbjct: 491 RGARGEPGGVGPIG--PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDP 548
Query: 515 SSPGSPGTPGSRSRT-------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 567
PG PG PG+R T P P+ P + R P P A+ + P
Sbjct: 549 GRPGEPGLPGARGLTGRPGDAGPQGKVGPSGAPGEDG--RPGPPGPQGARGQPGVMGFPG 606
Query: 568 PDLKNVKSKIGSTENLKHQPG 588
P N + + L PG
Sbjct: 607 PKGANGEPGKAGEKGLPGAPG 627
Score = 62.0 bits (149), Expect = 2e-09
Identities = 125/488 (25%), Positives = 155/488 (31%), Gaps = 88/488 (18%)
Query: 82 EGAPGKQAAAQPHTEI----PEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGF 136
EGAPGK I P G E+ +G P+ A G + E+G GF
Sbjct: 776 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 835
Query: 137 LREPGP---PGLSHQL----MSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLK 189
PG PG + G GAP P+GP A TG +G R A
Sbjct: 836 AGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGA----- 889
Query: 190 HQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTA 249
+GPP G PG+ V S+ PP P+ G+
Sbjct: 890 ---------QGPP----GATGFPGAAGRVGPPG----SNGNPGPPGPPGPS--GKDGPKG 930
Query: 250 AREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP--DGPSVGRAKGQDAPLEFTFHVEI 307
AR + PG E + P + EP DGPS A+G P
Sbjct: 931 ARGDSGPPGRAGEPGLQGPAGPPGE------KGEPGDDGPS--GAEGPPGPQGLAG---- 978
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKP 367
Q+ G FPG PG E + + P P P G+P
Sbjct: 979 ----QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 1034
Query: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS 427
R S DG D A P +PG + P +
Sbjct: 1035 --------GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1086
Query: 428 ----SPAVCPEPPSSPKHVSSVTSRTGSSGAK-------EMKLKGADGKTKIATPRGAAP 476
+ A P PS P + G G K E LKG G T + G P
Sbjct: 1087 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG--P 1144
Query: 477 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT------- 529
PG G A+ PA P P+ PP P SG PG G PG R R+
Sbjct: 1145 PGPSGDQGASG-PAG-PSGPRGPPGPVGP--SGKDGANGIPGPIGPPGPRGRSGETGPAG 1200
Query: 530 -PSLPTPP 536
P P PP
Sbjct: 1201 PPGNPGPP 1208
Score = 61.6 bits (148), Expect = 3e-09
Identities = 133/576 (23%), Positives = 185/576 (32%), Gaps = 89/576 (15%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
GT GL K GY +G+ A + +P E+GS P + P
Sbjct: 279 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGR 334
Query: 76 TAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIG--DTPSLEDEAAGHVTQEPE--SGKV 131
T P GA G QP P G G G P + EA + PE G
Sbjct: 335 TGPAGAAGARGND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392
Query: 132 VQEGFLREPGPPGLSHQL-------------MSGMPGAPLLPEGPREATRQPSGTGPEDT 178
+ G PGP G S G+ GAP P GPR TGP
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP-GPRGPPGPQGATGPLGP 451
Query: 179 EGGRHAPELLKHQLLGDLHQEGPP-------LKGAGGKE-RPGSKEEVDEDRDVDESSPQ 230
+G P + + G+ +G P G G+E + G++ E + +
Sbjct: 452 KGQTGEPGIAGFK--GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 509
Query: 231 DSPPSKASPAQDG----------RPPQTAA--REATSIPGFPAEGAIPLPVDFLSKVSTE 278
+P ++ P QDG R P A + A PG P E +P +
Sbjct: 510 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 569
Query: 279 IPASE------------PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA 326
P + P P A+GQ + F + A+ E G+A
Sbjct: 570 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP---------GPKGANGEP--GKAG 618
Query: 327 FPGAPGEGPEARG-PSLGEDTKEADLPEPS----EKQPAAAPRGKPVSRVPQLKARMVSK 381
G PG P RG P +T A P P+ E+ AP +P
Sbjct: 619 EKGLPG-APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 677
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
K G +A + + P G P P +P PK
Sbjct: 678 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-----DGPKG 732
Query: 442 VSSVTSRTGSSGAKEMK-LKGADGKTKIATPRG-------AAPPGQKGQANATRIPAKTP 493
S G+ G ++ + G G IA P+G P G G+ +
Sbjct: 733 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 792
Query: 494 PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT 529
P P ++GE + G S G+ G PG R T
Sbjct: 793 P-PGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 827
Score = 61.2 bits (147), Expect = 3e-09
Identities = 135/566 (23%), Positives = 180/566 (31%), Gaps = 118/566 (20%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAA-AQPHT 95
GD K P P EDG P A+ P P G PGK P
Sbjct: 567 GDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 625
Query: 96 EIPEGTTAE--EAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-------S 146
G + E G P AG + E G GF PGPPG
Sbjct: 626 PGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 681
Query: 147 HQLMSGMPGAPLL--PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP--- 201
Q + G GAP L P G R + G + +G R P G +GP
Sbjct: 682 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--------GTPGTDGPKGA 733
Query: 202 --PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGF 259
P G + PG + E + P+ +G P + R T G
Sbjct: 734 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 793
Query: 260 PAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSE 319
P + E P GP+ G A + AP E + +
Sbjct: 794 PGPAG----------ANGEKGEVGPPGPA-GSAGARGAPGE------------RGETGPP 830
Query: 320 EHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMV 379
G A PGA G+ P A+G GE ++ D P + P+ AP + + V K
Sbjct: 831 GPAGFAGPPGADGQ-PGAKGEQ-GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 888
Query: 380 SKSKDG-TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----------GSSDPLIQPSS 428
++ G TG + S N P P P G S P +
Sbjct: 889 AQGPPGATGFPGAAGRVGPPGS-----NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP-PGQKGQANATR 487
P + + P+ P G SGA+ G G +A RG PGQ+G+
Sbjct: 944 PGL--QGPAGPPGEKGEPGDDGPSGAE-----GPPGPQGLAGQRGIVGLPGQRGERGFPG 996
Query: 488 IPAKT----------------PPAPKTPPS----SGEPPKSG------------------ 509
+P + PP P PP +GEP + G
Sbjct: 997 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 1056
Query: 510 DRSGYSSPGSPGTPG-SRSRTPSLPT 534
DR + G+PG PG S P+ PT
Sbjct: 1057 DRGETGAVGAPGAPGPPGSPGPAGPT 1082
Score = 40.4 bits (93), Expect = 0.006
Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 466 TKIATPRGA-APPGQKGQANATR--IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGT 522
T +AT G P GQKG+ + + K PP P+ P +GE GDR G+PG
Sbjct: 91 TDLATASGQPGPKGQKGEPGDIKDIVGPKGPPGPQGP--AGEQGPRGDRGDKGEKGAPGP 148
Query: 523 PG--SRSRTPSLPTPP 536
G TP P PP
Sbjct: 149 RGRDGEPGTPGNPGPP 164
Score = 35.4 bits (80), Expect = 0.20
Identities = 45/175 (25%), Positives = 57/175 (32%), Gaps = 25/175 (14%)
Query: 38 DTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
D AG+K +T PG S + PT + D G G Q P
Sbjct: 1049 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-----DRGEAGAQGPMGPSG-- 1101
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P G + G P + AG + G G PGPPG S + P P
Sbjct: 1102 PAGARGIQGPQG--PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1159
Query: 158 LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERP 212
P GP P GP +G P G + GP +G G+ P
Sbjct: 1160 SGPRGP------PGPVGPSGKDGANGIP--------GPIGPPGP--RGRSGETGP 1198
Score = 34.3 bits (77), Expect = 0.44
Identities = 36/123 (29%), Positives = 47/123 (38%), Gaps = 26/123 (21%)
Query: 407 RPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKT 466
+ CLSP+ P G P +CP + + + +G G K K + D K
Sbjct: 73 KDCLSPEIPF-GECCP--------ICP---------TDLATASGQPGPKGQKGEPGDIKD 114
Query: 467 KIATPRGAAPPGQKGQAN-----ATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 521
I P+G PPG +G A R AP GEP G+ PG PG
Sbjct: 115 -IVGPKG--PPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPG 171
Query: 522 TPG 524
PG
Sbjct: 172 PPG 174
>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
sapiens]
Length = 1418
Score = 69.7 bits (169), Expect = 9e-12
Identities = 124/500 (24%), Positives = 161/500 (32%), Gaps = 111/500 (22%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA--GHVTQEPESGKVVQEGFLR 138
+ G PGK P P+G G TP L G+ + G+ G
Sbjct: 187 EAGKPGKAGERGPPG--PQGAR----GFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKG 240
Query: 139 EPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
E G PG +G PG P GPR + TGP G R G+ Q
Sbjct: 241 ESGSPG-----ENGSPG----PMGPRGLPGERGRTGPAGAAGAR-----------GNDGQ 280
Query: 199 EGP--------PLKGAGGKERPGSKEEVD----------EDRDVDESSPQDSPPSKAS-- 238
GP P G G PG+K E + + +P P+ AS
Sbjct: 281 PGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGN 340
Query: 239 PAQDGRPPQTAAREATSI---PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQ 295
P DG P + A I PGFP P P + P + P + KG+
Sbjct: 341 PGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGATGPLG---PKGQTGEPGIAGFKGE 397
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDTKEADLPEP 354
P + G A GAPG G E + + GE + P
Sbjct: 398 QGP--------------------KGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPP 437
Query: 355 SEK-----------QPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKT 403
E+ A P+G P R P A G D + A+
Sbjct: 438 GERGAPGNRGFPGQDGLAGPKGAPGERGPSGLA-----GPKGANGDPGRPGEPGLPGARG 492
Query: 404 LKNRPC-------LSP-----KHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGS 451
L RP + P + PG P P V P PK + + G
Sbjct: 493 LTGRPGDAGPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP--GPKGANGEPGKAGE 550
Query: 452 SGAKEMK----LKGADGKTKIATPRG-AAPPGQKGQANATRIPAKTPPAPKTPPSSGEPP 506
G L G DG+T A P G A P G++G+ A P+ P P GE
Sbjct: 551 KGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPG-PSGFQGLPGPPGPPGEGG 609
Query: 507 KSGDRSGYSSPGSPGTPGSR 526
K GD+ G+PG G R
Sbjct: 610 KPGDQGVPGEAGAPGLVGPR 629
Score = 62.0 bits (149), Expect = 2e-09
Identities = 126/554 (22%), Positives = 171/554 (30%), Gaps = 71/554 (12%)
Query: 78 PLVDEGAPG--KQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAA----GHVTQEPESGKV 131
P +G PG K P+G E+ GD ++ A G + G
Sbjct: 33 PKGQKGEPGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNP 92
Query: 132 VQEGFLREPGPPGLSHQLMSGMPGA---------------PLLPEGPREATRQPSGTGPE 176
G PGPPGL + M G P+ P GPR GP+
Sbjct: 93 GPPGPPGPPGPPGLGGNFAAQMAGGFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQ 152
Query: 177 DTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSK 236
+G P + + G + GPP G +PG E + E P ++
Sbjct: 153 GFQGNPGEPG--EPGVSGPMGPRGPP----GPPGKPGDDGEAGKPGKAGERGPPGPQGAR 206
Query: 237 ASPAQDGRPPQTAAREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEPDGP-SVGRAKGQ 295
P G P R + G E P V S E + P GP + +G+
Sbjct: 207 GFPGTPGLPGVKGHRGYPGLDGAKGEAGAP-GVKGESGSPGENGSPGPMGPRGLPGERGR 265
Query: 296 DAPLEFTFHVEITPNVQKEQAHSEEHLGRA---AFPGAPGEGPE-----ARGPSLGEDTK 347
P + Q A +G A FPGAPG E ARGP G
Sbjct: 266 TGPAGAA--GARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPE-GAQGP 322
Query: 348 EADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGT-GSDDKKAKTSTRSSAKTLKN 406
+ P PA A +P K + G G + + +
Sbjct: 323 RGEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQGAT----- 377
Query: 407 RPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKT 466
P P + +P I P+ P G G +GA G+
Sbjct: 378 ----GPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGK-----RGARGEP 428
Query: 467 KIATPRGAAPPGQKGQANATRIPAKTPPA-PKTPPS----SGEPPKSGDRSGYSSPGSPG 521
P G PPG++G P + A PK P SG G PG PG
Sbjct: 429 GGVGPIG--PPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPG 486
Query: 522 TPGSRSRT-------PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPMPDLKNVK 574
PG+R T P P+ P + R P P A+ + P P N +
Sbjct: 487 LPGARGLTGRPGDAGPQGKVGPSGAPGEDG--RPGPPGPQGARGQPGVMGFPGPKGANGE 544
Query: 575 SKIGSTENLKHQPG 588
+ L PG
Sbjct: 545 PGKAGEKGLPGAPG 558
Score = 62.0 bits (149), Expect = 2e-09
Identities = 125/488 (25%), Positives = 155/488 (31%), Gaps = 88/488 (18%)
Query: 82 EGAPGKQAAAQPHTEI----PEGTTAEEAGIGDT-PSLEDEAAGHVTQEPESGKVVQEGF 136
EGAPGK I P G E+ +G P+ A G + E+G GF
Sbjct: 707 EGAPGKDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGF 766
Query: 137 LREPGP---PGLSHQL----MSGMPGAPLLPEGPREATRQPSGTGPEDTEGGRHAPELLK 189
PG PG + G GAP P+GP A TG +G R A
Sbjct: 767 AGPPGADGQPGAKGEQGEAGQKGDAGAPG-PQGPSGAPGPQGPTGVTGPKGARGA----- 820
Query: 190 HQLLGDLHQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTA 249
+GPP G PG+ V S+ PP P+ G+
Sbjct: 821 ---------QGPP----GATGFPGAAGRVGPPG----SNGNPGPPGPPGPS--GKDGPKG 861
Query: 250 AREATSIPGFPAEGAIPLPVDFLSKVSTEIPASEP--DGPSVGRAKGQDAPLEFTFHVEI 307
AR + PG E + P + EP DGPS A+G P
Sbjct: 862 ARGDSGPPGRAGEPGLQGPAGPPGE------KGEPGDDGPS--GAEGPPGPQGLAG---- 909
Query: 308 TPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKP 367
Q+ G FPG PG E + + P P P G+P
Sbjct: 910 ----QRGIVGLPGQRGERGFPGLPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEP 965
Query: 368 VSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPS 427
R S DG D A P +PG + P +
Sbjct: 966 --------GREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG 1017
Query: 428 ----SPAVCPEPPSSPKHVSSVTSRTGSSGAK-------EMKLKGADGKTKIATPRGAAP 476
+ A P PS P + G G K E LKG G T + G P
Sbjct: 1018 DRGEAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPG--P 1075
Query: 477 PGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT------- 529
PG G A+ PA P P+ PP P SG PG G PG R R+
Sbjct: 1076 PGPSGDQGASG-PAG-PSGPRGPPGPVGP--SGKDGANGIPGPIGPPGPRGRSGETGPAG 1131
Query: 530 -PSLPTPP 536
P P PP
Sbjct: 1132 PPGNPGPP 1139
Score = 61.6 bits (148), Expect = 3e-09
Identities = 133/576 (23%), Positives = 185/576 (32%), Gaps = 89/576 (15%)
Query: 16 GTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDV 75
GT GL K GY +G+ A + +P E+GS P + P
Sbjct: 210 GTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGP----MGPRGLPGERGR 265
Query: 76 TAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGIG--DTPSLEDEAAGHVTQEPE--SGKV 131
T P GA G QP P G G G P + EA + PE G
Sbjct: 266 TGPAGAAGARGND--GQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323
Query: 132 VQEGFLREPGPPGLSHQL-------------MSGMPGAPLLPEGPREATRQPSGTGPEDT 178
+ G PGP G S G+ GAP P GPR TGP
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFP-GPRGPPGPQGATGPLGP 382
Query: 179 EGGRHAPELLKHQLLGDLHQEGPP-------LKGAGGKE-RPGSKEEVDEDRDVDESSPQ 230
+G P + + G+ +G P G G+E + G++ E + +
Sbjct: 383 KGQTGEPGIAGFK--GEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPIGPPGER 440
Query: 231 DSPPSKASPAQDG----------RPPQTAA--REATSIPGFPAEGAIPLPVDFLSKVSTE 278
+P ++ P QDG R P A + A PG P E +P +
Sbjct: 441 GAPGNRGFPGQDGLAGPKGAPGERGPSGLAGPKGANGDPGRPGEPGLPGARGLTGRPGDA 500
Query: 279 IPASE------------PDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAA 326
P + P P A+GQ + F + A+ E G+A
Sbjct: 501 GPQGKVGPSGAPGEDGRPGPPGPQGARGQPGVMGFP---------GPKGANGEP--GKAG 549
Query: 327 FPGAPGEGPEARG-PSLGEDTKEADLPEPS----EKQPAAAPRGKPVSRVPQLKARMVSK 381
G PG P RG P +T A P P+ E+ AP +P
Sbjct: 550 EKGLPG-APGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGLPGPPGPPGEG 608
Query: 382 SKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEPPSSPKH 441
K G +A + + P G P P +P PK
Sbjct: 609 GKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLPGTPGT-----DGPKG 663
Query: 442 VSSVTSRTGSSGAKEMK-LKGADGKTKIATPRG-------AAPPGQKGQANATRIPAKTP 493
S G+ G ++ + G G IA P+G P G G+ +
Sbjct: 664 ASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIG 723
Query: 494 PAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT 529
P P ++GE + G S G+ G PG R T
Sbjct: 724 P-PGPAGANGEKGEVGPPGPAGSAGARGAPGERGET 758
Score = 61.2 bits (147), Expect = 3e-09
Identities = 135/566 (23%), Positives = 180/566 (31%), Gaps = 118/566 (20%)
Query: 37 GDTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAA-AQPHT 95
GD K P P EDG P A+ P P G PGK P
Sbjct: 498 GDAGPQGKVGPSGAPGEDGRPGPPGPQG-ARGQPGVMGFPGPKGANGEPGKAGEKGLPGA 556
Query: 96 EIPEGTTAE--EAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGL-------S 146
G + E G P AG + E G GF PGPPG
Sbjct: 557 PGLRGLPGKDGETGAAGPPG----PAGPAGERGEQGAPGPSGFQGLPGPPGPPGEGGKPG 612
Query: 147 HQLMSGMPGAPLL--PEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP--- 201
Q + G GAP L P G R + G + +G R P G +GP
Sbjct: 613 DQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGLQGPRGLP--------GTPGTDGPKGA 664
Query: 202 --PLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSIPGF 259
P G + PG + E + P+ +G P + R T G
Sbjct: 665 SGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPGKDGGRGLTGPIGP 724
Query: 260 PAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSE 319
P + E P GP+ G A + AP E + +
Sbjct: 725 PGPAG----------ANGEKGEVGPPGPA-GSAGARGAPGE------------RGETGPP 761
Query: 320 EHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMV 379
G A PGA G+ P A+G GE ++ D P + P+ AP + + V K
Sbjct: 762 GPAGFAGPPGADGQ-PGAKGEQ-GEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARG 819
Query: 380 SKSKDG-TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTP----------GSSDPLIQPSS 428
++ G TG + S N P P P G S P +
Sbjct: 820 AQGPPGATGFPGAAGRVGPPGS-----NGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874
Query: 429 PAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP-PGQKGQANATR 487
P + + P+ P G SGA+ G G +A RG PGQ+G+
Sbjct: 875 PGL--QGPAGPPGEKGEPGDDGPSGAE-----GPPGPQGLAGQRGIVGLPGQRGERGFPG 927
Query: 488 IPAKT----------------PPAPKTPPS----SGEPPKSG------------------ 509
+P + PP P PP +GEP + G
Sbjct: 928 LPGPSGEPGKQGAPGASGDRGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKG 987
Query: 510 DRSGYSSPGSPGTPG-SRSRTPSLPT 534
DR + G+PG PG S P+ PT
Sbjct: 988 DRGETGAVGAPGAPGPPGSPGPAGPT 1013
Score = 38.9 bits (89), Expect = 0.018
Identities = 25/69 (36%), Positives = 31/69 (44%), Gaps = 6/69 (8%)
Query: 472 RGAAPPGQKGQANATR--IPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG--SRS 527
R P GQKG+ + + K PP P+ P +GE GDR G+PG G
Sbjct: 29 RQPGPKGQKGEPGDIKDIVGPKGPPGPQGP--AGEQGPRGDRGDKGEKGAPGPRGRDGEP 86
Query: 528 RTPSLPTPP 536
TP P PP
Sbjct: 87 GTPGNPGPP 95
Score = 35.4 bits (80), Expect = 0.20
Identities = 45/175 (25%), Positives = 57/175 (32%), Gaps = 25/175 (14%)
Query: 38 DTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
D AG+K +T PG S + PT + D G G Q P
Sbjct: 980 DGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQG-----DRGEAGAQGPMGPSG-- 1032
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P G + G P + AG + G G PGPPG S + P P
Sbjct: 1033 PAGARGIQGPQG--PRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSGDQGASGPAGP 1090
Query: 158 LLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERP 212
P GP P GP +G P G + GP +G G+ P
Sbjct: 1091 SGPRGP------PGPVGPSGKDGANGIP--------GPIGPPGP--RGRSGETGP 1129
>gi|239754955 PREDICTED: similar to COL22A1 protein [Homo sapiens]
Length = 1073
Score = 69.7 bits (169), Expect = 9e-12
Identities = 129/514 (25%), Positives = 158/514 (30%), Gaps = 58/514 (11%)
Query: 50 TPTEDGSE-EPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEGTTAEEAGI 108
TP +DG E G+ + P P D GAPG + G
Sbjct: 426 TPGKDGERGEKGAAGEEGSPGPVG-----PRGDPGAPGLPGPPGKGKDGEPGLRGSPGLP 480
Query: 109 GDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMS----GMPGAPLLPEGPR 164
G + D A + P S G PGP G S G+PG P P+GP
Sbjct: 481 GPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPGFPG-PQGPA 539
Query: 165 EATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGA----GGKERPGSKEEVDE 220
S P D LL + D P L G G K PG
Sbjct: 540 GRDGLSSLLSPGDIN-------LLAKDVCNDCPPGPPGLPGLPGFKGDKGVPGKPGREGT 592
Query: 221 DRDVDESSPQD--SPPSKASP-------AQDGRPPQTAAREATSIPGFPAEGAIPLPVDF 271
+ E+ P PP A P DG Q + +PGF P P
Sbjct: 593 EGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGA 652
Query: 272 LSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAP 331
P P G P P + E+ GR PG P
Sbjct: 653 DGIAGAAGPPGIQGSPGKEGPPGPQGPSGL-------PGIPGEEGKE----GRDGKPGPP 701
Query: 332 GEGPEARGPSL-GEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDG-TGSD 389
GE +A P L G + + AP + S L + KDG TG
Sbjct: 702 GEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPT 761
Query: 390 DKKAKTSTRSSAKTLKNRPCLSPKHP----TPGSSDPLIQPSSPAVC----PEPPSSPKH 441
+ R KN SP P TPG + SP + P P
Sbjct: 762 GPQGPQGPRGPPG--KNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPRGPPGEPG 819
Query: 442 VSSVTSRTGSSGAK-EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP 500
V + G G E KG G I +G PPG KGQ IP P
Sbjct: 820 EKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKG--PPGGKGQPGDPGIPGHKGHTGLMGP 877
Query: 501 SSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLPT 534
G P ++G PG PG PG R +PS+ T
Sbjct: 878 Q-GLPGENGPVGPPGPPGQPGFPGLRGESPSMET 910
Score = 67.0 bits (162), Expect = 6e-11
Identities = 138/529 (26%), Positives = 176/529 (33%), Gaps = 115/529 (21%)
Query: 40 DAGLKESP-LQ-TPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
D GL P LQ P E G + P AK A + GAPG A P
Sbjct: 357 DPGLPGEPGLQGRPGELGPQGPTGPPG-AKGQEGAHGAPGAAGNPGAPGHVGAPGPSG-- 413
Query: 98 PEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAP 157
P G+ G+ TP + E E G +EG PGP G G PGAP
Sbjct: 414 PPGSVGAP-GLRGTPGKDGERG-------EKGAAGEEG---SPGPVG-----PRGDPGAP 457
Query: 158 LLPEGPREATR-------QPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKE 210
LP P + P GP T+G R AP + G G P G G
Sbjct: 458 GLPGPPGKGKDGEPGLRGSPGLPGPLGTKGDRGAPGIP-----GSPGSRGDPGIGVAGP- 511
Query: 211 RPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRP----PQ-TAAREATSIPGFPAEGAI 265
PG P P K SP G P PQ A R+ S P +
Sbjct: 512 -PG---------------PSGPPGDKGSPGSRGLPGFPGPQGPAGRDGLSSLLSPGD--- 552
Query: 266 PLPVDFLSK-VSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGR 324
++ L+K V + P P P + KG P + +E G
Sbjct: 553 ---INLLAKDVCNDCPPGPPGLPGLPGFKGDKG----------VPGKPGREG-TEGKKGE 598
Query: 325 AAFPGAPGEGPEARGP--SLGEDTKEADLPEPSEKQPAAAP--RGKPVSRVPQLKARMVS 380
A PG PG P GP S GE + ++ + ++ P G P + P +
Sbjct: 599 AGPPGLPGP-PGIAGPQGSQGERGADGEVGQKGDQGHPGVPGFMGPPGNPGPPGADGIAG 657
Query: 381 KSKDG--TGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQPSSPAVCPEP--- 435
+ GS K+ + + L P K G P P P EP
Sbjct: 658 AAGPPGIQGSPGKEGPPGPQGPSG-LPGIPGEEGKEGRDGKPGP---PGEPGKAGEPGLP 713
Query: 436 -PSSPKHVSSVTSRTGSSGAKEMK-------------LKGADGKTKIATPRGA----APP 477
P + TG SGA + L G DG T P+G PP
Sbjct: 714 GPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLPGKDGDTGPTGPQGPQGPRGPP 773
Query: 478 GQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSR 526
G+ G +P +P P SG P + G + SPG PG G R
Sbjct: 774 GKNG----------SPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 812
Score = 62.4 bits (150), Expect = 2e-09
Identities = 132/552 (23%), Positives = 177/552 (32%), Gaps = 104/552 (18%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREP 140
D+G G+ + E A AG P H E G ++G P
Sbjct: 302 DQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLP 361
Query: 141 GPPGLSHQLMSGMPG--APLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQ 198
G PGL G PG P P GP A Q G G AP +G
Sbjct: 362 GEPGL-----QGRPGELGPQGPTGPPGAKGQEGAHGAPGAAGNPGAP-----GHVGAPGP 411
Query: 199 EGPP-------LKGAGGKE-RPGSKEEVDEDRDVDESSPQDSP-----PSKASPAQDGRP 245
GPP L+G GK+ G K E+ P+ P P +DG P
Sbjct: 412 SGPPGSVGAPGLRGTPGKDGERGEKGAAGEEGSPGPVGPRGDPGAPGLPGPPGKGKDGEP 471
Query: 246 PQTAA------------REATSIPGFPAEGAIP------------LPVDFLSKVSTEIPA 281
+ R A IPG P P P D S S +P
Sbjct: 472 GLRGSPGLPGPLGTKGDRGAPGIPGSPGSRGDPGIGVAGPPGPSGPPGDKGSPGSRGLPG 531
Query: 282 -SEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGEGPEARGP 340
P GP+ G+D +I N+ + ++ G PG PG + P
Sbjct: 532 FPGPQGPA-----GRDGLSSLLSPGDI--NLLAKDVCNDCPPGPPGLPGLPGFKGDKGVP 584
Query: 341 SLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSS 400
G+ +E + E P P G P PQ S+ G+D + + +
Sbjct: 585 --GKPGREGTEGKKGEAGPPGLP-GPPGIAGPQ-------GSQGERGADGEVGQKGDQGH 634
Query: 401 AKTLKNRPCLSPKHPTPGSSDPLIQPSSP-----AVCPEPPSSPKHVSSVTSRTGSSGAK 455
P +P P +D + + P + E P P+ S + G G
Sbjct: 635 PGVPGFMG--PPGNPGPPGADGIAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGK- 691
Query: 456 EMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKTPPAPKTPP-------SSGEPPKS 508
+G DGK PPG+ G+A +P P + PP SG P
Sbjct: 692 ----EGRDGK--------PGPPGEPGKAGEPGLPG--PEGARGPPGFKGHTGDSGAPGPR 737
Query: 509 GDRSGYSSPGSPGTPGSRSRT-PSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTAPVPM 567
G+ PG G PG T P+ P P R PP S S + P
Sbjct: 738 GESGAMGLPGQEGLPGKDGDTGPTGPQGPQGP-------RGPPGKNGSPGSPGEPGPSGT 790
Query: 568 PDLKNVKSKIGS 579
P K K + GS
Sbjct: 791 PGQKGSKGENGS 802
Score = 58.9 bits (141), Expect = 2e-08
Identities = 133/538 (24%), Positives = 173/538 (32%), Gaps = 153/538 (28%)
Query: 81 DEGAPGKQAAAQPHTEIPEGTTAEEA--GIGDTPSL--------EDEAAGHVTQEPESGK 130
D+G PGK P E EG E G+ P + E A G V Q+ + G
Sbjct: 580 DKGVPGK-----PGREGTEGKKGEAGPPGLPGPPGIAGPQGSQGERGADGEVGQKGDQGH 634
Query: 131 VVQEGFLR---EPGPPGLSHQLMSGMPGAPLL--------PEGPREATRQPSGTGPEDTE 179
GF+ PGPPG ++G G P + P GP+ + P G E E
Sbjct: 635 PGVPGFMGPPGNPGPPGADG--IAGAAGPPGIQGSPGKEGPPGPQGPSGLPGIPGEEGKE 692
Query: 180 G--GRHAP-----ELLKHQLLGDLHQEGPP-LKG-------------AGGKERPGSKEEV 218
G G+ P + + L G GPP KG +G PG +
Sbjct: 693 GRDGKPGPPGEPGKAGEPGLPGPEGARGPPGFKGHTGDSGAPGPRGESGAMGLPGQEGLP 752
Query: 219 DEDRDVDESSPQD------------SPPSKASPAQDGRPPQTAAREATSIPGFPA----- 261
+D D + PQ SP S P G P Q ++ PG P
Sbjct: 753 GKDGDTGPTGPQGPQGPRGPPGKNGSPGSPGEPGPSGTPGQKGSKGENGSPGLPGFLGPR 812
Query: 262 --------------EGAIPLPVDFLSKVSTEIPASEPD-GPSVGRAKGQDAPLEFTFHVE 306
EG P + K P + D GP G KGQ H
Sbjct: 813 GPPGEPGEKGVPGKEGVPGKPGEPGFKGERGDPGIKGDKGPPGG--KGQPGDPGIPGHKG 870
Query: 307 ITPNVQKEQAHSEEHLGRAAFPGAPGEG--PEARGPSLGEDTKEADLPEPSEKQPAAAPR 364
T + + E G PG PG+ P RG S +T + E KQ
Sbjct: 871 HTGLMGPQGLPGEN--GPVGPPGPPGQPGFPGLRGESPSMETLRRLIQEELGKQLE---- 924
Query: 365 GKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLI 424
+R+ L A+M + S++ P K PG + P+
Sbjct: 925 ----TRLAYLLAQM---------------PPAYMKSSQGRPGPPGPPGKDGLPGRAGPMG 965
Query: 425 QPSSPAVCP-EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQA 483
+P P E PS P G GA + L+G G PPG GQ
Sbjct: 966 EPGRPGQGGLEGPSGPIGPKGERGAKGDPGAPGVGLRGEMG-----------PPGIPGQP 1014
Query: 484 NATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRT-----PSLPTPP 536
GEP GY+ G PG PG + T P LP PP
Sbjct: 1015 -------------------GEP-------GYAKDGLPGIPGPQGETGPAGHPGLPGPP 1046
Score = 50.1 bits (118), Expect = 8e-06
Identities = 70/256 (27%), Positives = 94/256 (36%), Gaps = 38/256 (14%)
Query: 323 GRAAFPGAPG-------EGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLK 375
G A PGAPG +G + LG + D E E PA P + +
Sbjct: 283 GEAGLPGAPGFPGVRGEKGDQGEKGELGLPGLKGDRGEKGEAGPAGPPGLPGTTSLFTPH 342
Query: 376 ARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPC-LSPKHPT--PGSSDPLIQPSSPAVC 432
RM + G +K L+ RP L P+ PT PG+ +P
Sbjct: 343 PRMPGEQ----GPKGEKGDPGLPGEPG-LQGRPGELGPQGPTGPPGAKGQEGAHGAPGAA 397
Query: 433 PEPPSSPKHVSSV--TSRTGSSGAKEMKLKGADGKTKIATPRGAA-------PPGQKGQA 483
P +P HV + + GS GA L+G GK +GAA P G +G
Sbjct: 398 GNP-GAPGHVGAPGPSGPPGSVGAPG--LRGTPGKDGERGEKGAAGEEGSPGPVGPRGDP 454
Query: 484 NATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPGSRSRTPSLP-TPPTREPKK 542
A +P PP G+ + G R PG GT G R P +P +P +R
Sbjct: 455 GAPGLPG--------PPGKGKDGEPGLRGSPGLPGPLGTKGDRG-APGIPGSPGSRGDPG 505
Query: 543 VAVVRTP-PKSPSSAK 557
+ V P P P K
Sbjct: 506 IGVAGPPGPSGPPGDK 521
Score = 42.7 bits (99), Expect = 0.001
Identities = 119/500 (23%), Positives = 163/500 (32%), Gaps = 129/500 (25%)
Query: 55 GSEEPGSETSDAKSTPTAEDVTAPLVDE--GAPGKQAAAQPHTEIPEGTTAEEAGIGDTP 112
G++ P + +DA+++ TAP + + G PG++ E G+ P
Sbjct: 220 GTQGPADQRADARASCILAAKTAPGLKQLNGEPGERG---------------EDGLPGKP 264
Query: 113 SLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPGAPLLPEGPREATRQPSG 172
L G++ ++G PG G +G+PGAP P E
Sbjct: 265 GLR-------------GEIGEQGLAGRPGEKG-----EAGLPGAPGFPGVRGEK------ 300
Query: 173 TGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEE-VDEDRDVDESSPQD 231
G + +G P L + G+ + GP AG PG+ R E P+
Sbjct: 301 -GDQGEKGELGLPGLKGDR--GEKGEAGP----AGPPGLPGTTSLFTPHPRMPGEQGPKG 353
Query: 232 S---PPSKASPAQDGRPPQTAAREATSIPGFPA-EGAIPLPVDFLSKVSTEIPASEPDGP 287
P P GRP + + T PG EGA P A P P
Sbjct: 354 EKGDPGLPGEPGLQGRPGELGPQGPTGPPGAKGQEGAHGAPG----------AAGNPGAP 403
Query: 288 SVGRAKGQDAPLEFTFHVEITPNVQKEQAHSEEHLGRAAFPGAPGE-GPEARGPSLGEDT 346
A G P + K+ E+ G A G+PG GP D
Sbjct: 404 GHVGAPGPSGPPGSVGAPGLRGTPGKDGERGEK--GAAGEEGSPGPVGPRG-------DP 454
Query: 347 KEADLPEPSEKQPAAAPRGKPVSR-VPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLK 405
LP P P G+P R P L + +K G
Sbjct: 455 GAPGLPGP----PGKGKDGEPGLRGSPGLPGPLGTKGDRG-------------------- 490
Query: 406 NRPCLSPKHP-TPGS-SDPLIQPSSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGAD 463
+P P +PGS DP I + P P P P S SR G D
Sbjct: 491 -----APGIPGSPGSRGDPGIGVAGP---PGPSGPPGDKGSPGSRGLPGFPGPQGPAGRD 542
Query: 464 GKTKIATPRGAAPPGQKGQAN--ATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPG 521
G + + +P G N A + PP P P G P GD+ PG PG
Sbjct: 543 GLSSLLSP---------GDINLLAKDVCNDCPPGP--PGLPGLPGFKGDKG---VPGKPG 588
Query: 522 TPGSRSR-----TPSLPTPP 536
G+ + P LP PP
Sbjct: 589 REGTEGKKGEAGPPGLPGPP 608
Score = 35.8 bits (81), Expect = 0.15
Identities = 49/192 (25%), Positives = 64/192 (33%), Gaps = 30/192 (15%)
Query: 367 PVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPGSSDPLIQP 426
P +P+ S + G D++A S K P L + PG P
Sbjct: 203 PQCSMPKGTGHEFSAALGTQGPADQRADARA-SCILAAKTAPGLKQLNGEPGERGEDGLP 261
Query: 427 SSPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADG-------------KTKIATPRG 473
P + E + R G G E L GA G K ++ P
Sbjct: 262 GKPGLRGEIGEQ-----GLAGRPGEKG--EAGLPGAPGFPGVRGEKGDQGEKGELGLPGL 314
Query: 474 AAPPGQKGQANATRIPAKTPPAPKTP----PSSGEPPKSGDRSGYSSPGSPGTPGSRSRT 529
G+KG+A PA P P T P P + G + PG PG PG + R
Sbjct: 315 KGDRGEKGEAG----PAGPPGLPGTTSLFTPHPRMPGEQGPKGEKGDPGLPGEPGLQGRP 370
Query: 530 PSL-PTPPTREP 540
L P PT P
Sbjct: 371 GELGPQGPTGPP 382
>gi|207113164 Treacher Collins-Franceschetti syndrome 1 isoform f
[Homo sapiens]
Length = 1412
Score = 69.3 bits (168), Expect = 1e-11
Identities = 128/596 (21%), Positives = 207/596 (34%), Gaps = 87/596 (14%)
Query: 38 DTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
DT + E+ ++ + + + ++ AK TP AP PGK A T+
Sbjct: 202 DTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP------PGKAGAVASQTKA 255
Query: 98 PEGTTAEEAGIGDTPSLEDE--AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG 155
+ E+ ++ E+E AA + Q SGK Q G P PG
Sbjct: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
Query: 156 --APLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQ------LLGDLHQEGPPLKGAG 207
P + + + S + E+++ AP K + P KGA
Sbjct: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 375
Query: 208 G----KERPGSKE-----EVDEDRDVDESSPQDSPPSKASPAQD----GRPPQTAAREAT 254
K P + + + ++ R E S D A A G+ PQ
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 255 SIPGFPAEGAIPLPVDFLSKV--STEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
+ G +GA P+P + S ++ E D S + E+ V
Sbjct: 436 GM-GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD------GEVPTAVA 488
Query: 313 KEQAHSEEHLGRAAFPGAPGEGPEAR-GPSL-----------GEDTKEADLPEPSEKQPA 360
Q S ++ +A +P +GP + GP E ++E+ SE+ PA
Sbjct: 489 PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 548
Query: 361 A--APRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPG 418
A A + KP ++PQ KA K T + K A + A K SP +P
Sbjct: 549 AMTAAQAKPALKIPQTKA---CPKKTNTTASAKVAPVRVGTQAPR-KAGTATSPAGSSPA 604
Query: 419 SSDPLIQPSSPAVCPEPPSSPKHVS--SVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
+ +P+ + E S + + +VT S K +++K A K + +G AP
Sbjct: 605 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 664
Query: 477 --PGQKGQA----------------------NATRIPAKTPPAPKTPPSSGEPPKSGDRS 512
PG+ G A PA+ + K + P + S
Sbjct: 665 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 724
Query: 513 GYSSPGSPG-----TPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 563
+ +PG ++ R+PS PP R P+ V+ P S S + TA
Sbjct: 725 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
Score = 44.7 bits (104), Expect = 3e-04
Identities = 124/556 (22%), Positives = 180/556 (32%), Gaps = 126/556 (22%)
Query: 49 QTPTEDGSEEPGSETSDAKSTPTAEDVT---APLVDEGAPGKQAAAQPHTEIPEGTTA-- 103
Q P ED S SE SD++ T VT A V +G K A+ + +GT
Sbjct: 610 QRPAEDSSS---SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL 666
Query: 104 ----------------EEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSH 147
E++ + S +EAA Q S K Q + P
Sbjct: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA----KANPAAARA 722
Query: 148 QLMSGMPGAP--LLPEGPREATRQPSGTGPED---------TEGGRHAPELLKHQLLGDL 196
G AP ++ + R PS P G P + K
Sbjct: 723 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 782
Query: 197 HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI 256
Q GP +E GS EE + + E+ Q P K + P A+E+
Sbjct: 783 AQTGP-------EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKES--- 829
Query: 257 PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA 316
P +GA P P GPS +A QD +
Sbjct: 830 ---PRKGAAPTPPG-------------KTGPSAAQAGKQD----------------DSGS 857
Query: 317 HSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKA 376
SEE P A + P + D P S PAA P + P+
Sbjct: 858 SSEESDSDGEAPAAVTSAQVIKPPLIFVD------PNRSPAGPAATPAQAQAASTPRKAR 911
Query: 377 RMVSKSKDGTG-SDDKKAKTST-------RSSAKTLKN-RPCLSPKHPTPGSSD------ 421
S ++ + S+D+ +T R++ T+ P ++PK G+S
Sbjct: 912 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSR 971
Query: 422 ---------PLIQPS--SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
P Q S +PA P ++ K ++ S A+ G D + + T
Sbjct: 972 ISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD--SAVGT 1029
Query: 471 PRGAAPPGQKGQANAT------RIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG 524
+P QA T ++P + A K P SS + S D S S G G
Sbjct: 1030 LPATSPQSTSVQAKGTNKLRKPKLP-EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
Query: 525 SRS-RTPSLPTPPTRE 539
++S T PTP E
Sbjct: 1089 AKSAHTLVGPTPSRTE 1104
Score = 42.0 bits (97), Expect = 0.002
Identities = 100/478 (20%), Positives = 171/478 (35%), Gaps = 53/478 (11%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
AG S + DG ++ G T +K P + +T + A K + AQP +
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ-KASEAQPPVARTQP 1019
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGF--LREPGPPGLSHQLMSGMPGAPL 158
++ ++ +G P+ P+S V +G LR+P P + AP
Sbjct: 1020 SSGVDSAVGTLPATS----------PQSTSVQAKGTNKLRKPKLPEVQQATK-----APE 1064
Query: 159 LPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGPPLKGAGGKERPGSKEEV 218
+ +++ SG+ ED EG + A H L+G L E ++
Sbjct: 1065 SSDDSEDSSDSSSGS-EEDGEGPQGAKSA--HTLVGPTPSRTETLV-----EETAAESSE 1116
Query: 219 DEDRDVDES----------SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPLP 268
D+ +S +P +S SKA+P D P ++ A P E
Sbjct: 1117 DDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQA 1176
Query: 269 VDFLSKVSTEIPASEPDGPSVGRA--KGQDAPLEFTFHVE--ITPNVQKEQAHSEEHLGR 324
LS + A+ P R KG P T ++ IT + + E +
Sbjct: 1177 AGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQ 1236
Query: 325 AAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSKD 384
A+ E E + + TKE+ + E + +P +R P+ K + + +
Sbjct: 1237 ASVVKVLTELLEQERKKVVDTTKESSR-KGWESRKRKLSGDQPAARTPRSKKKKKLGAGE 1295
Query: 385 GTGSDDKKAKTSTRSSAKTLKNRPCLSPKHP-------TPGSSD---PLIQPSSPAVCPE 434
G + KTST S K +++ K + G+ D +Q V
Sbjct: 1296 GGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGG 1355
Query: 435 PPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492
S+PK S + K+ + K K K A+ + + P QK + + +T
Sbjct: 1356 DQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1411
>gi|57164975 Treacher Collins-Franceschetti syndrome 1 isoform b
[Homo sapiens]
Length = 1411
Score = 69.3 bits (168), Expect = 1e-11
Identities = 128/596 (21%), Positives = 207/596 (34%), Gaps = 87/596 (14%)
Query: 38 DTDAGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEI 97
DT + E+ ++ + + + ++ AK TP AP PGK A T+
Sbjct: 202 DTSSSSDETDVEVKASEKILQVRAASAPAKGTPGKGATPAP------PGKAGAVASQTKA 255
Query: 98 PEGTTAEEAGIGDTPSLEDE--AAGHVTQEPESGKVVQEGFLREPGPPGLSHQLMSGMPG 155
+ E+ ++ E+E AA + Q SGK Q G P PG
Sbjct: 256 GKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPG 315
Query: 156 --APLLPEGPREATRQPSGTGPEDTEGGRHAPELLKHQ------LLGDLHQEGPPLKGAG 207
P + + + S + E+++ AP K + P KGA
Sbjct: 316 KTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAA 375
Query: 208 G----KERPGSKE-----EVDEDRDVDESSPQDSPPSKASPAQD----GRPPQTAAREAT 254
K P + + + ++ R E S D A A G+ PQ
Sbjct: 376 PAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTM 435
Query: 255 SIPGFPAEGAIPLPVDFLSKV--STEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQ 312
+ G +GA P+P + S ++ E D S + E+ V
Sbjct: 436 GM-GPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSD------GEVPTAVA 488
Query: 313 KEQAHSEEHLGRAAFPGAPGEGPEAR-GPSL-----------GEDTKEADLPEPSEKQPA 360
Q S ++ +A +P +GP + GP E ++E+ SE+ PA
Sbjct: 489 PAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPA 548
Query: 361 A--APRGKPVSRVPQLKARMVSKSKDGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHPTPG 418
A A + KP ++PQ KA K T + K A + A K SP +P
Sbjct: 549 AMTAAQAKPALKIPQTKA---CPKKTNTTASAKVAPVRVGTQAPR-KAGTATSPAGSSPA 604
Query: 419 SSDPLIQPSSPAVCPEPPSSPKHVS--SVTSRTGSSGAKEMKLKGADGKTKIATPRGAAP 476
+ +P+ + E S + + +VT S K +++K A K + +G AP
Sbjct: 605 VAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAP 664
Query: 477 --PGQKGQA----------------------NATRIPAKTPPAPKTPPSSGEPPKSGDRS 512
PG+ G A PA+ + K + P + S
Sbjct: 665 VLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPS 724
Query: 513 GYSSPGSPG-----TPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAKSRLQTA 563
+ +PG ++ R+PS PP R P+ V+ P S S + TA
Sbjct: 725 AKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATA 780
Score = 47.0 bits (110), Expect = 7e-05
Identities = 123/555 (22%), Positives = 179/555 (32%), Gaps = 125/555 (22%)
Query: 49 QTPTEDGSEEPGSETSDAKSTPTAEDVT---APLVDEGAPGKQAAAQPHTEIPEGTTA-- 103
Q P ED S SE SD++ T VT A V +G K A+ + +GT
Sbjct: 610 QRPAEDSSS---SEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVL 666
Query: 104 ----------------EEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGFLREPGPPGLSH 147
E++ + S +EAA Q S K Q + P
Sbjct: 667 PGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQA----KANPAAARA 722
Query: 148 QLMSGMPGAP--LLPEGPREATRQPSGTGPED---------TEGGRHAPELLKHQLLGDL 196
G AP ++ + R PS P G P + K
Sbjct: 723 PSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQ 782
Query: 197 HQEGPPLKGAGGKERPGSKEEVDEDRDVDESSPQDSPPSKASPAQDGRPPQTAAREATSI 256
Q GP +E GS EE + + E+ Q P K + P A+E+
Sbjct: 783 AQTGP-------EEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAP---AKES--- 829
Query: 257 PGFPAEGAIPLPVDFLSKVSTEIPASEPDGPSVGRAKGQDAPLEFTFHVEITPNVQKEQA 316
P +GA P P GPS +A QD +
Sbjct: 830 ---PRKGAAPTPPG-------------KTGPSAAQAGKQD----------------DSGS 857
Query: 317 HSEEHLGRAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKA 376
SEE P A + P + D P S PAA P + P+
Sbjct: 858 SSEESDSDGEAPAAVTSAQVIKPPLIFVD------PNRSPAGPAATPAQAQAASTPRKAR 911
Query: 377 RMVSKSKDGTG-SDDKKAKTST-------RSSAKTLKN-RPCLSPKHPTPGSSD------ 421
S ++ + S+D+ +T R++ T+ P ++PK G+S
Sbjct: 912 ASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSR 971
Query: 422 ---------PLIQPS--SPAVCPEPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIAT 470
P Q S +PA P ++ K ++ S A+ G D + + T
Sbjct: 972 ISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVD--SAVGT 1029
Query: 471 PRGAAPPGQKGQANAT------RIPAKTPPAPKTPPSSGEPPKSGDRSGYSSPGSPGTPG 524
+P QA T ++P + A K P SS + S D S S G G
Sbjct: 1030 LPATSPQSTSVQAKGTNKLRKPKLP-EVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQG 1088
Query: 525 SRSRTPSLPTPPTRE 539
++S PTP E
Sbjct: 1089 AKSAHTLGPTPSRTE 1103
Score = 41.2 bits (95), Expect = 0.004
Identities = 100/479 (20%), Positives = 171/479 (35%), Gaps = 56/479 (11%)
Query: 41 AGLKESPLQTPTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG 100
AG S + DG ++ G T +K P + +T + A K + AQP +
Sbjct: 961 AGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQ-KASEAQPPVARTQP 1019
Query: 101 TTAEEAGIGDTPSLEDEAAGHVTQEPESGKVVQEGF--LREPGPPGLSHQLMSGMPGAPL 158
++ ++ +G P+ P+S V +G LR+P P + AP
Sbjct: 1020 SSGVDSAVGTLPATS----------PQSTSVQAKGTNKLRKPKLPEVQQATK-----APE 1064
Query: 159 LPEGPREATRQPSGTGPEDTEGGRHAPELLKHQLLGDLHQEGP-PLKGAGGKERPGSKEE 217
+ +++ SG+ ED EG + A H GP P + E ++
Sbjct: 1065 SSDDSEDSSDSSSGS-EEDGEGPQGAKSA---------HTLGPTPSRTETLVEETAAESS 1114
Query: 218 VDEDRDVDES----------SPQDSPPSKASPAQDGRPPQTAAREATSIPGFPAEGAIPL 267
D+ +S +P +S SKA+P D P ++ A P E
Sbjct: 1115 EDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQ 1174
Query: 268 PVDFLSKVSTEIPASEPDGPSVGRA--KGQDAPLEFTFHVE--ITPNVQKEQAHSEEHLG 323
LS + A+ P R KG P T ++ IT + + E
Sbjct: 1175 AAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQV 1234
Query: 324 RAAFPGAPGEGPEARGPSLGEDTKEADLPEPSEKQPAAAPRGKPVSRVPQLKARMVSKSK 383
+A+ E E + + TKE+ + E + +P +R P+ K + +
Sbjct: 1235 QASVVKVLTELLEQERKKVVDTTKESSR-KGWESRKRKLSGDQPAARTPRSKKKKKLGAG 1293
Query: 384 DGTGSDDKKAKTSTRSSAKTLKNRPCLSPKHP-------TPGSSD---PLIQPSSPAVCP 433
+G + KTST S K +++ K + G+ D +Q V
Sbjct: 1294 EGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEG 1353
Query: 434 EPPSSPKHVSSVTSRTGSSGAKEMKLKGADGKTKIATPRGAAPPGQKGQANATRIPAKT 492
S+PK S + K+ + K K K A+ + + P QK + + +T
Sbjct: 1354 GDQSNPK--SKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQT 1410
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.304 0.127 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 40,692,194
Number of Sequences: 37866
Number of extensions: 2741042
Number of successful extensions: 25746
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 269
Number of HSP's successfully gapped in prelim test: 1840
Number of HSP's that attempted gapping in prelim test: 12071
Number of HSP's gapped (non-prelim): 8583
length of query: 758
length of database: 18,247,518
effective HSP length: 110
effective length of query: 648
effective length of database: 14,082,258
effective search space: 9125303184
effective search space used: 9125303184
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.