Guide to the Human Genome
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Name: SIRT6 Sequence: fasta or formatted (355aa) NCBI GI: 7706710
Description:

sirtuin 6

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         29           2
 C cysteine            1.7          6           1
 D aspartate           5.1         18           1
 E glutamate           7.0         25           2
 F phenylalanine       2.3          8           1
 G glycine             7.9         28           2
 H histidine           3.1         11           1
 I isoleucine          3.1         11           1
 K lysine              5.1         18           1
 L leucine            10.4         37           2
 M methionine          2.0          7           1
 N asparagine          2.3          8           1
 P proline             9.6         34           2
 Q glutamine           2.5          9           1
 R arginine            9.0         32           2
 S serine              5.9         21           3
 T threonine           5.9         21           2
 V valine              6.5         23           2
 W tryptophan          1.4          5           1
 Y tyrosine            1.1          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sirtuin 6 
SIRT7                 0.216   sirtuin 7 
SIRT4                 0.088   sirtuin 4 
SIRT3                 0.084   sirtuin 3 isoform a 
SIRT3                 0.078   sirtuin 3 isoform b 
SIRT2                 0.067   sirtuin 2 isoform 1 
SIRT2                 0.067   sirtuin 2 isoform 2 
SIRT1                 0.064   sirtuin 1 isoform a 
SIRT5                 0.048   sirtuin 5 isoform 2 
SIRT5                 0.048   sirtuin 5 isoform 1 
SIRT1                 0.040   sirtuin 1 isoform b 
SEC24C                0.024   SEC24-related protein C 
SEC24C                0.024   SEC24-related protein C 
PRG4                  0.023   proteoglycan 4 isoform D 
PRG4                  0.023   proteoglycan 4 isoform C 
PRG4                  0.023   proteoglycan 4 isoform B 
PRG4                  0.023   proteoglycan 4 isoform A 
KDM6B                 0.021   lysine (K)-specific demethylase 6B 
SAMD1                 0.020   sterile alpha motif domain containing 1 
BAT2                  0.020   HLA-B associated transcript-2 
OGFR                  0.017   opioid growth factor receptor 
LOC100134209          0.017   PREDICTED: similar to IQ motif and SEC7 domain-cont...
LOC731035             0.017   PREDICTED: hypothetical protein 
LOC100288881          0.017   PREDICTED: hypothetical protein XP_002343185 
SETD1A                0.017   SET domain containing 1A 
ATF7                  0.017   activating transcription factor 7 isoform 2 
ATF7                  0.017   activating transcription factor 7 isoform 1 
PRR12                 0.017   proline rich 12 
LOC728056             0.017   PREDICTED: similar to IQ motif and SEC7 domain-cont...
FLJ22184              0.017   PREDICTED: hypothetical protein FLJ22184 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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