Guide to the Human Genome
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Name: SIRT1 Sequence: fasta or formatted (452aa) NCBI GI: 215982798
Description:

sirtuin 1 isoform b

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Other entries for this name:
alt prot [747aa] sirtuin 1 isoform a
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         22           2
 C cysteine            3.3         15           2
 D aspartate           7.1         32           2
 E glutamate          10.2         46           2
 F phenylalanine       3.8         17           2
 G glycine             5.3         24           2
 H histidine           2.0          9           1
 I isoleucine          6.0         27           2
 K lysine              5.5         25           1
 L leucine             7.7         35           2
 M methionine          1.5          7           1
 N asparagine          4.4         20           1
 P proline             7.7         35           2
 Q glutamine           4.2         19           1
 R arginine            4.6         21           2
 S serine              9.1         41           4
 T threonine           3.3         15           1
 V valine              6.4         29           2
 W tryptophan          0.2          1           1
 Y tyrosine            2.7         12           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sirtuin 1 isoform b 
SIRT1                 1.000   sirtuin 1 isoform a 
SIRT2                 0.158   sirtuin 2 isoform 1 
SIRT2                 0.158   sirtuin 2 isoform 2 
SIRT3                 0.145   sirtuin 3 isoform b 
SIRT3                 0.145   sirtuin 3 isoform a 
SIRT5                 0.050   sirtuin 5 isoform 1 
SIRT5                 0.047   sirtuin 5 isoform 2 
SIRT4                 0.036   sirtuin 4 
SIRT6                 0.031   sirtuin 6 
YTHDC1                0.013   splicing factor YT521-B isoform 2 
YTHDC1                0.013   splicing factor YT521-B isoform 1 
AP3B2                 0.013   adaptor-related protein complex 3, beta 2 subunit [H...
C14orf174             0.013   hypothetical protein LOC161394 
EIF4G3                0.012   eukaryotic translation initiation factor 4 gamma, 3 ...
PHLDB2                0.012   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.012   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.012   pleckstrin homology-like domain, family B, member 2...
PHLDB2                0.012   pleckstrin homology-like domain, family B, member 2 ...
MSL3                  0.011   male-specific lethal 3-like 1 isoform a 
MSL3                  0.011   male-specific lethal 3-like 1 isoform b 
MSL3                  0.011   male-specific lethal 3-like 1 isoform d 
ANKRD12               0.009   ankyrin repeat domain 12 isoform 2 
ANKRD12               0.009   ankyrin repeat domain 12 isoform 1 
CDC2L1                0.009   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.009   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.009   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.009   cell division cycle 2-like 1 (PITSLRE proteins) isof...
CDC2L1                0.009   cell division cycle 2-like 1 (PITSLRE proteins) isof...
ZZZ3                  0.008   zinc finger, ZZ-type containing 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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