Guide to the Human Genome
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Name: SIRT2 Sequence: fasta or formatted (389aa) NCBI GI: 13775600
Description:

sirtuin 2 isoform 1

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Other entries for this name:
alt prot [352aa] sirtuin 2 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.5         29           2
 C cysteine            2.8         11           1
 D aspartate           6.2         24           1
 E glutamate           8.2         32           1
 F phenylalanine       4.9         19           2
 G glycine             7.2         28           3
 H histidine           2.1          8           1
 I isoleucine          3.6         14           1
 K lysine              6.4         25           2
 L leucine            11.3         44           3
 M methionine          2.6         10           1
 N asparagine          1.3          5           1
 P proline             6.7         26           3
 Q glutamine           4.4         17           1
 R arginine            4.6         18           2
 S serine              8.7         34           1
 T threonine           4.1         16           2
 V valine              3.9         15           1
 W tryptophan          0.8          3           1
 Y tyrosine            2.8         11           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sirtuin 2 isoform 1 
SIRT2                 0.904   sirtuin 2 isoform 2 
SIRT3                 0.343   sirtuin 3 isoform a 
SIRT3                 0.319   sirtuin 3 isoform b 
SIRT1                 0.237   sirtuin 1 isoform a 
SIRT1                 0.185   sirtuin 1 isoform b 
SIRT4                 0.063   sirtuin 4 
SIRT6                 0.061   sirtuin 6 
SIRT5                 0.056   sirtuin 5 isoform 2 
SIRT5                 0.055   sirtuin 5 isoform 1 
SIRT7                 0.048   sirtuin 7 
DCAF5                 0.012   WD repeat domain 22 
TLE2                  0.009   transducin-like enhancer protein 2 isoform 2 
TLE2                  0.009   transducin-like enhancer protein 2 isoform 1 
LOC100290265          0.007   PREDICTED: hypothetical protein XP_002346787 
SYMPK                 0.007   symplekin 
HCN2                  0.007   hyperpolarization activated cyclic nucleotide-gated...
RSL1D1                0.007   ribosomal L1 domain containing 1 
PALM                  0.007   paralemmin isoform 2 
PALM                  0.007   paralemmin isoform 1 
TIGD4                 0.007   tigger transposable element derived 4 
KIAA1543              0.005   NEZHA isoform 2 
KIAA1543              0.005   NEZHA isoform 1 
SPEG                  0.005   SPEG complex locus 
GTPBP1                0.005   GTP binding protein 1 
GFRAL                 0.005   GDNF family receptor alpha like 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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