Guide to the Human Genome
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Name: SIRT1 Sequence: fasta or formatted (747aa) NCBI GI: 7657575
Description:

sirtuin 1 isoform a

Referenced in:

Histones, Related Proteins, and Modifying Enzymes

Other entries for this name:
alt prot [452aa] sirtuin 1 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.8         66           5
 C cysteine            2.5         19           2
 D aspartate           7.8         58           4
 E glutamate          10.2         76           5
 F phenylalanine       2.9         22           2
 G glycine             7.0         52           2
 H histidine           1.6         12           1
 I isoleucine          5.8         43           2
 K lysine              4.6         34           2
 L leucine             7.6         57           2
 M methionine          1.3         10           1
 N asparagine          3.5         26           1
 P proline             8.6         64           3
 Q glutamine           3.7         28           2
 R arginine            5.5         41           2
 S serine              7.6         57           4
 T threonine           3.3         25           1
 V valine              5.0         37           2
 W tryptophan          0.5          4           1
 Y tyrosine            2.1         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   sirtuin 1 isoform a 
SIRT1                 0.601   sirtuin 1 isoform b 
SIRT2                 0.122   sirtuin 2 isoform 1 
SIRT2                 0.122   sirtuin 2 isoform 2 
SIRT3                 0.113   sirtuin 3 isoform a 
SIRT3                 0.106   sirtuin 3 isoform b 
SIRT5                 0.046   sirtuin 5 isoform 1 
SIRT5                 0.044   sirtuin 5 isoform 2 
SIRT4                 0.037   sirtuin 4 
SIRT6                 0.030   sirtuin 6 
SOX12                 0.015   SRY (sex determining region Y)-box 12 
MARCKS                0.013   myristoylated alanine-rich protein kinase C substra...
RBM42                 0.013   RNA binding motif protein 42 
HDGFL1                0.013   hepatoma derived growth factor-like 1 
COL7A1                0.013   alpha 1 type VII collagen precursor 
CLIC6                 0.011   chloride intracellular channel 6 
LOC100127891          0.011   PREDICTED: hypothetical protein 
ARID1A                0.011   AT rich interactive domain 1A isoform a 
ARID1A                0.011   AT rich interactive domain 1A isoform b 
LMTK3                 0.011   lemur tyrosine kinase 3 
COL28A1               0.011   collagen, type XXVIII precursor 
COL11A1               0.011   alpha 1 type XI collagen isoform B preproprotein [Ho...
COL11A1               0.011   alpha 1 type XI collagen isoform C preproprotein [Ho...
COL11A1               0.011   alpha 1 type XI collagen isoform A preproprotein [Ho...
DAXX                  0.011   death-domain associated protein isoform a 
DAXX                  0.011   death-domain associated protein isoform a 
DAXX                  0.011   death-domain associated protein isoform b 
BASP1                 0.011   brain abundant, membrane attached signal protein 1 [...
MEX3D                 0.011   ring finger and KH domain containing 1 
SOX3                  0.010   SRY (sex determining region Y)-box 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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