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Search of human proteins with 7706635
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7706635 cornulin [Homo sapiens]
(495 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7706635 cornulin [Homo sapiens] 991 0.0
gi|171916097 repetin [Homo sapiens] 128 1e-29
gi|57864582 hornerin [Homo sapiens] 118 1e-26
gi|62122917 filaggrin family member 2 [Homo sapiens] 116 4e-26
gi|148746195 trichohyalin [Homo sapiens] 103 3e-22
gi|60097902 filaggrin [Homo sapiens] 103 5e-22
gi|56606114 trichohyalin-like 1 [Homo sapiens] 82 9e-16
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 65 2e-10
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 64 3e-10
gi|5174663 S100 calcium binding protein P [Homo sapiens] 63 7e-10
gi|5032059 S100 calcium-binding protein A12 [Homo sapiens] 60 5e-09
gi|239754269 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|169168665 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|113417486 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239740898 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo ... 57 3e-08
gi|239740777 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239740724 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239740674 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239740645 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|239513940 PREDICTED: hypothetical protein [Homo sapiens] 57 3e-08
gi|119220598 apolipoprotein B48 receptor [Homo sapiens] 57 3e-08
gi|5454034 S100 calcium-binding protein, beta [Homo sapiens] 54 3e-07
gi|5454032 S100 calcium binding protein A1 [Homo sapiens] 52 9e-07
gi|21614544 S100 calcium-binding protein A8 [Homo sapiens] 52 1e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 52 2e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 52 2e-06
gi|91208420 bassoon protein [Homo sapiens] 52 2e-06
gi|161016767 mucin 21 [Homo sapiens] 52 2e-06
gi|4757898 calbindin 3 [Homo sapiens] 52 2e-06
>gi|7706635 cornulin [Homo sapiens]
Length = 495
Score = 991 bits (2561), Expect = 0.0
Identities = 495/495 (100%), Positives = 495/495 (100%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL
Sbjct: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG
Sbjct: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
Query: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERIS 180
TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERIS
Sbjct: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERIS 180
Query: 181 PQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQ 240
PQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQ
Sbjct: 181 PQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQ 240
Query: 241 TVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ 300
TVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ
Sbjct: 241 TVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ 300
Query: 301 TVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ 360
TVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ
Sbjct: 301 TVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ 360
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST
Sbjct: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
Query: 421 HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG
Sbjct: 421 HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
Query: 481 ITARELYSYLRSTKP 495
ITARELYSYLRSTKP
Sbjct: 481 ITARELYSYLRSTKP 495
>gi|171916097 repetin [Homo sapiens]
Length = 784
Score = 128 bits (322), Expect = 1e-29
Identities = 133/531 (25%), Positives = 212/531 (39%), Gaps = 67/531 (12%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M QLL +I +I+ F +YA+ G+C L + ELK+LL EF D++ +P+DP TV+ +L L
Sbjct: 1 MAQLLNSILSVIDVFHKYAKGNGDCALLCKEELKQLLLAEFGDILQRPNDPETVETILNL 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQE---------------SGSL 105
LD+D G ++F E+L+LVF++ QAC+ L + G SQ+ +G
Sbjct: 61 LDQDRDGHIDFHEYLLLVFQLVQACYHKLDNKSHGGRTSQQERGQEGAQDCKFPGNTGRQ 120
Query: 106 HSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVS 165
H +E E Q S G + G RQ + GQ+ + Q + + +
Sbjct: 121 HRQRHEE--ERQNSHHSQPERQDGDSHHGQPERQDRDSHHGQS----EKQDRDSHHSQPE 174
Query: 166 SYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKR--NQTTEMRPERQPQTREQDRAH-- 221
DR + ER Q+Q + GK+ +++T + + Q +R
Sbjct: 175 RQDRDSHHNQSERQDKDFSFDQSERQSQDSSSGKKVSHKSTSGQAKWQGHIFALNRCEKP 234
Query: 222 -------QTGETVTGSGTQTQAG-ATQTVEQDSSHQTGRTSKQTQEATNDQ--NRGTETH 271
Q+ S T QA QT +Q S G++ + QE Q +G +H
Sbjct: 235 IQDSHYGQSERHTQQSETLGQASHFNQTNQQKSGSYCGQSERLGQELGCGQTDRQGQSSH 294
Query: 272 GQGRSQTSQAVTGGHA--QIQAGTHTQTP--------TQTVEQDSSHQTGSTSTQTQ--- 318
+ Q+ G Q Q+ ++QT +Q Q S G + Q
Sbjct: 295 YGQTDRQDQSYHYGQTDRQGQSSHYSQTDRQGQSSHYSQPDRQGQSSHYGQMDRKGQCYH 354
Query: 319 -ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQT 377
+ TN Q +G+ R S TQ Q+ + +T QD+S +G QGQ+
Sbjct: 355 YDQTNRQGQGSHYSQPNRQGQSSHYGQPDTQDQSSHYGQTDRQDQSS--HYGQTERQGQS 412
Query: 378 -----QTQPGSGQRWMQVSNPEAGETV--PGGQAQTGASTESGRQEWSSTHPRRCVTEGQ 430
+ G G + Q P Q Q ++ RQ SS + GQ
Sbjct: 413 SHYSQMDRQGQGSHYGQTDRQGQSSHYGQPDRQGQNSHYGQTDRQGQSSHY-------GQ 465
Query: 431 GDRQPTVVGEEWVDDHSRETVILRLDQ--GNLHTSVSSAQGQDAAQSEEKR 479
DRQ D + + ++D+ + H QGQ + + R
Sbjct: 466 TDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQPDGQGQSSHYGQTDR 516
Score = 55.1 bits (131), Expect = 1e-07
Identities = 93/398 (23%), Positives = 148/398 (37%), Gaps = 85/398 (21%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHY-----EGSSHRQSQQ 142
T +S+ ++ S H G ++ G+ +++ R G+G HY +G S Q
Sbjct: 384 TQDQSSHYGQTDRQDQSSHYGQTERQGQSSHY-SQMDRQGQGSHYGQTDRQGQSSHYGQP 442
Query: 143 GSRGQNRPGVQT--QGQATG---------SAWVSSYDRQAESQSQERISPQIQL------ 185
+GQN QT QGQ++ S+ S D+Q +S +I Q Q
Sbjct: 443 DRQGQNSHYGQTDRQGQSSHYGQTDRQGQSSHYSQPDKQGQSSHYGKIDRQDQSYHYGQP 502
Query: 186 SGQTEQTQKAGEGKRNQTTEM-RPERQPQTREQDRAHQTGETVTGSGTQTQAGAT---QT 241
GQ + + ++ Q+ +P+RQ Q+ + + G++ T Q ++ QT
Sbjct: 503 DGQGQSSHYGQTDRQGQSFHYGQPDRQGQSSHYSQMDRQGQSSHYGQTDRQGQSSHYGQT 562
Query: 242 VEQDSSHQTGRTSKQTQEATNDQNRGTETHGQ-------------------GRS-QTSQA 281
Q S+ G+T +Q Q + Q++ E GQ GRS + SQ
Sbjct: 563 DRQGQSYHYGQTDRQGQSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQ 622
Query: 282 VTG--GHAQIQAGTHTQTPTQT------VEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQ 333
G G+ G ++ Q E+DS H Q Q+ + +
Sbjct: 623 TPGQEGYQNQGQGFQSRDSQQNGHQVWEPEEDSQHHQHKLLAQIQQE-------RPLCHK 675
Query: 334 GRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNP 393
GR S + GH Q Q Q + +SH EQG Q W + S+
Sbjct: 676 GRDWQSCSSEQGHRQAQ-------TRQSHGEGLSHWAEEEQGH--------QTWDRHSH- 719
Query: 394 EAGETVPGGQAQTGASTESGRQ-------EWSSTHPRR 424
E+ E G Q + E Q E +H RR
Sbjct: 720 ESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQRR 757
Score = 38.5 bits (88), Expect = 0.014
Identities = 61/206 (29%), Positives = 80/206 (38%), Gaps = 42/206 (20%)
Query: 100 QESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQA 158
Q S + S + G+ + GTE R G S R SQQ + GQ G Q QGQ
Sbjct: 579 QSSHYIQSQTGEIQGQNKYFQGTEGTRKASYVEQSGRSGRLSQQ-TPGQE--GYQNQGQG 635
Query: 159 TGS---------AWVSSYDRQAESQSQERISPQIQLS------GQTEQTQKAGEGKRN-Q 202
S W D Q Q ++ QIQ G+ Q+ + +G R Q
Sbjct: 636 FQSRDSQQNGHQVWEPEEDSQ---HHQHKLLAQIQQERPLCHKGRDWQSCSSEQGHRQAQ 692
Query: 203 TTEMRPERQPQTREQDRAHQT-----GETVTG-SGTQT----------QAGATQTVEQDS 246
T + E E+++ HQT E+ G GTQ Q QT E +
Sbjct: 693 TRQSHGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQ 752
Query: 247 SHQTGRTSKQTQE-ATNDQNRGTETH 271
SHQ R +QT E N Q R +TH
Sbjct: 753 SHQ--RRDRQTHEDKQNRQRRDRQTH 776
Score = 29.3 bits (64), Expect = 8.6
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 131 HYEGSSH-RQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQT 189
H EG SH + +QG + +R ++Q G+ ++ + Q ++R + + + S Q
Sbjct: 697 HGEGLSHWAEEEQGHQTWDRHSHESQEGPCGTQDRRTHKDEQNHQRRDRQTHEHEQSHQR 756
Query: 190 EQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQ 222
Q E K+N R R QT E ++ HQ
Sbjct: 757 RDRQ-THEDKQN-----RQRRDRQTHEDEQNHQ 783
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 118 bits (296), Expect = 1e-26
Identities = 129/533 (24%), Positives = 203/533 (38%), Gaps = 57/533 (10%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
MP+LLQ + +I+ F +YA G L + ELK LLE EF ++ P+DP TVD +L+
Sbjct: 1 MPKLLQGVITVIDVFYQYATQHGEYDTLNKAELKELLENEFHQILKNPNDPDTVDIILQS 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
LD DH V+F E+L+++FK+ QA K + + GS+ H ++ +
Sbjct: 61 LDRDHNKKVDFTEYLLMIFKLVQARNKIIGKDYCQVSGSKLRDDTHQHQEEQEETEKEEN 120
Query: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT-----------QGQATG-SAWVSSYD 168
+ + + + RG +PG ++ GQ S SSY
Sbjct: 121 KRQESSFSHSSWSAGENDSYSRNVRGSLKPGTESISRRLSFQRDFSGQHNSYSGQSSSYG 180
Query: 169 RQAESQSQERISPQI-QLSGQTEQTQKAGEGK-RNQTTEMRPERQPQT-----REQDRAH 221
Q Q Q SGQ+ + G G ++ + + Q+ +
Sbjct: 181 EQNSDSHQSSGRGQCGSGSGQSPNYGQHGSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQ 240
Query: 222 QTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATND---------QNRGTETHG 272
+G + GSG+ +G Q + G + + +++ Q+ G G
Sbjct: 241 SSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQG 300
Query: 273 QGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-----QESTNGQNRG 327
G Q+ V G + +H Q + + S S S QT ES +GQ+ G
Sbjct: 301 SGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSG 360
Query: 328 TEIHGQGRSQTSQAVTGGHTQIQA---GSHTETVEQDRS-------QTVSHGGAREQGQT 377
HG G +S G T QA G H + Q S S G + +
Sbjct: 361 YSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQSSSYGQHESASRHSSGRGQHSSGS 420
Query: 378 QTQPGSGQRWM-QVSNPEAGETVPG-GQAQ--------TGASTESGRQEWSSTHPRRCVT 427
PG GQR +P +G+ G G++ +G S+ G E SS H
Sbjct: 421 GQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHHESSSEHSSGYTQ 480
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
G G + G+ SR R ++ SS+ GQ + S + G
Sbjct: 481 HGSGSGHSSGHGQH----GSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLG 529
Score = 77.4 bits (189), Expect = 3e-14
Identities = 89/369 (24%), Positives = 135/369 (36%), Gaps = 39/369 (10%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRP 150
+ G+ S G SG+ Q G GQ +G +H GS H S QG G
Sbjct: 324 QHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGH-SSSQGQHGS--- 379
Query: 151 GVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQT----QKAGEGKRNQTTEM 206
T GQA+ S S RQ+ S Q S SG+ + + Q G G+R +
Sbjct: 380 ---TSGQASSSGQHGSSSRQSSSYGQHE-SASRHSSGRGQHSSGSGQSPGHGQRGSGSGQ 435
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
P R+ +G V+GSG + G E S H +G T + + +
Sbjct: 436 SPSSGQHGTGFGRSSSSGPYVSGSGYSSGFGHH---ESSSEHSSGYTQ---HGSGSGHSS 489
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
G HG Q+S+ G + + ++ Q + + + + GS S Q+ + G++
Sbjct: 490 GHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHE 549
Query: 327 ---------GTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQT 377
G +G GRS + G H E+ S HG + T
Sbjct: 550 SGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSST 609
Query: 378 QTQPGSGQRWMQVSNPEAGETVPGGQ--AQTGASTESGRQEWSSTHPRRCVTEGQGDRQP 435
Q GS +G++ GQ A +G S+ G+ S+ R +G G Q
Sbjct: 610 HGQHGS----------TSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQS 659
Query: 436 TVVGEEWVD 444
G D
Sbjct: 660 PSRGRHGSD 668
Score = 68.6 bits (166), Expect = 1e-11
Identities = 103/414 (24%), Positives = 160/414 (38%), Gaps = 55/414 (13%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSR-GQ 147
+ G+ S SG SG+ Q G G + +G QH GS H S Q GSR GQ
Sbjct: 1847 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 1906
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
+ G Q G ++GS+ SSY + Q G + +G+
Sbjct: 1907 SSRGEQ-HGSSSGSS--SSYGQHGSGSRQS--------LGHGQHGSGSGQSP-------S 1948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRG 267
P R ++ G +GSG + G E S H +G + E+ + Q+ G
Sbjct: 1949 PSRGRHGSGSGQSSSYGPYGSGSGWSSSRG---PYESGSGHSSGLGHR---ESRSGQSSG 2002
Query: 268 TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-----QESTN 322
HG +S G A Q+ + Q + + S Q GS S+Q+ Q S +
Sbjct: 2003 YGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGS 2062
Query: 323 GQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQ-----DRSQTVSHGGAREQGQT 377
GQ+ G HGQ S + Q+ + G +G + + + + S H + Q +
Sbjct: 2063 GQSPG---HGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSS 2119
Query: 378 QTQPGSGQRWMQVSNPEAGETVPGGQ--AQTGASTESGRQEWSSTHPRRCVTEGQGDRQP 435
+Q GSG +G + GQ +++G S+ R SS R G G RQ
Sbjct: 2120 YSQHGSG----------SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
Query: 436 TVVGEEWV-DDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYS 488
+ G + HS R G+ H+S G + +S + +R +S
Sbjct: 2170 SGHGRQGSGSGHSPSRG--RHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHS 2221
Score = 65.5 bits (158), Expect = 1e-10
Identities = 97/368 (26%), Positives = 132/368 (35%), Gaps = 34/368 (9%)
Query: 92 SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGS-----RG 146
S+ G GS S S G E G GQ SG GQH GS SQ GS
Sbjct: 789 SSHGQHGSGTSCSSSCG-HYESGSGQASGF-------GQHESGSGQGYSQHGSASGHFSS 840
Query: 147 QNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQ----TEQTQKAGEGKRNQ 202
Q R G T GQ++ S S Q+ S Q S SG+ + Q G G+R
Sbjct: 841 QGRHG-STSGQSSSSGQHDSSSGQSSSYGQHE-SASHHASGRGRHGSGSGQSPGHGQRGS 898
Query: 203 TTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQ-----TGRTSKQT 257
+ P R+ +G +GSG + G + Q S + +G +S
Sbjct: 899 GSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYE 958
Query: 258 QEAT-NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQ 316
Q + + Q+ +E HG +S G Q+ H Q + + + S + S
Sbjct: 959 QHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGS 1018
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
Q S+ G R G G S + G H E+ S HG +
Sbjct: 1019 GQSSSYGPYRS----GSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSS 1074
Query: 377 TQTQPG--SGQ-RWMQVSNPEAGETVPGGQAQTGASTES--GRQEWSSTHPRRCVTEGQG 431
T Q G SGQ +G++ GQ +G+S S GRQ S G G
Sbjct: 1075 THGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSG 1134
Query: 432 DRQPTVVG 439
RQ G
Sbjct: 1135 SRQSPSYG 1142
Score = 65.1 bits (157), Expect = 1e-10
Identities = 83/351 (23%), Positives = 134/351 (38%), Gaps = 39/351 (11%)
Query: 94 EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHY---EGSSHRQSQQGSRGQNR 149
E + G S S H SG+ G GQ G+ G++ +G+ + GSS R Q GS +
Sbjct: 2111 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQS 2169
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
G QG +G + S R SG + + G G ++ E
Sbjct: 2170 SGHGRQGSGSGHS--PSRGRHGSG------------SGHSSSHGQHGSGSGRSSSRGPYE 2215
Query: 210 RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQT-GRTSKQTQEATND-QNRG 267
+ H++G + + +Q +G+ Q T G++S QE ++ Q+
Sbjct: 2216 SRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSS 2275
Query: 268 TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRG 327
HG G SQ+S G Q+ + + + + S Q GS S + S +
Sbjct: 2276 HGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS 2335
Query: 328 TEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT------VSHGGAREQGQTQTQ 380
+ G G ++S + G+TQ +GS H+ + EQ S++ HG + + Q
Sbjct: 2336 GQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQ 2395
Query: 381 PGSGQRWM-----------QVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
GSG R Q +P G G + S WSS+
Sbjct: 2396 HGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSS 2446
Score = 64.3 bits (155), Expect = 2e-10
Identities = 100/422 (23%), Positives = 157/422 (37%), Gaps = 40/422 (9%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQN 148
+ G+ S SG SG+ Q G G + +G QH GS H S Q GSR
Sbjct: 1377 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQ 1436
Query: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQL-SGQTEQTQKAGEGKRN-QTTEM 206
+ G ++GS+ SSY + Q Q SGQ+ + G + Q++
Sbjct: 1437 SSRGERHGSSSGSS--SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSY 1494
Query: 207 RP---------ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH--QTGRTSK 255
P R P + G + SG + G + SS Q G TS
Sbjct: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSG 1554
Query: 256 QTQE-----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQT 310
Q+ A++ Q+ HG G SQ+S G Q+ H Q + + + S +
Sbjct: 1555 QSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRH 1614
Query: 311 GSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT---- 365
GS S ++ S + E G G ++S + ++Q +GS H+ Q S++
Sbjct: 1615 GSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSS 1674
Query: 366 --VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPR 423
HG + Q GSG R +G G + +G S GR H
Sbjct: 1675 RGERHGSSSRSSSRYGQHGSGSR------QSSGHGRQG--SGSGQSPSRGRHGSGLGHSS 1726
Query: 424 RCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGI 481
G G + + G + +V + + G+ H+S S G + S+ + G
Sbjct: 1727 SHGQHGSGSGRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGS 1785
Query: 482 TA 483
T+
Sbjct: 1786 TS 1787
Score = 63.2 bits (152), Expect = 5e-10
Identities = 98/414 (23%), Positives = 150/414 (36%), Gaps = 65/414 (15%)
Query: 94 EGACGSQESGSLH--SGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151
EG+ Q S H SG+SQ G G+ +G+H GS H S G G
Sbjct: 1326 EGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGH-SSSYGQHG----- 1379
Query: 152 VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
+GS W SS R Q S Q SG T+ +G + + E
Sbjct: 1380 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSG---HSSSYEQ 1429
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
R Q+ +R H + + S Q +G+ Q++ Q G S Q+ + +
Sbjct: 1430 HGSRSGQSSRGER-HGSSSGSSSSYGQHGSGSRQSL---GHGQHGSGSGQSPSPSRGR-- 1483
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
HG G Q+S ++ +G+ + E SSH +G +ES +GQ+
Sbjct: 1484 ----HGSGSGQSS-----SYSPYGSGSGWSSSRGPYESGSSHSSG---LGHRESRSGQSS 1531
Query: 327 G----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
G + HGQ S + Q+ + G +G + + + S G R+
Sbjct: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
Query: 377 TQTQPGSGQRWM-QVSNPE-------AGETVPGGQAQTGASTES--GRQEWSSTHPRRCV 426
+ PG GQR +P +G + GQ +G S G E SS
Sbjct: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
Query: 427 TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
G G + G+ SR R ++ + SS GQ + S + G
Sbjct: 1652 QHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSG 1701
Score = 63.2 bits (152), Expect = 5e-10
Identities = 111/445 (24%), Positives = 163/445 (36%), Gaps = 61/445 (13%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
S G+ S G SG+S G G R +G GQH S H S G G
Sbjct: 1495 SPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTS 1553
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
+ GQ S+ SS Q S S + Q SG Q G G+R + P
Sbjct: 1554 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPS 1610
Query: 210 RQPQTREQDRAHQTGETVTGSGT-------QTQAGATQTVEQDSS--------HQTGRTS 254
R+ +G+ +G G ++ +G + + Q S Q G S
Sbjct: 1611 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRS 1670
Query: 255 KQTQ--EATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ-----TVEQDSS 307
Q+ E +R + +GQ S + Q + GH + +G+ Q+P++ + SS
Sbjct: 1671 GQSSRGERHGSSSRSSSRYGQHGSGSRQ--SSGHGRQGSGS-GQSPSRGRHGSGLGHSSS 1727
Query: 308 H-QTGSTSTQTQ-----ESTNGQNR--GTEIHGQGRSQT-SQAVTG-GH--TQIQAGS-- 353
H Q GS S ++ ES +G + G G G S SQ +G GH +Q Q GS
Sbjct: 1728 HGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1787
Query: 354 -HTETVEQDRSQT------VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQT 406
+ T +Q+ S T HG Q + Q GSG +P G G +
Sbjct: 1788 GQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSG----QSPSRGRHGSGSGHSS 1843
Query: 407 GASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSS 466
WSS+ R GQ W + + + G+ H+S
Sbjct: 1844 SYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSW-----QSSGYTQHGSGSGHSSSYE 1898
Query: 467 AQGQDAAQSE--EKRGITARELYSY 489
G + QS E+ G ++ SY
Sbjct: 1899 QHGSRSGQSSRGEQHGSSSGSSSSY 1923
Score = 63.2 bits (152), Expect = 5e-10
Identities = 76/308 (24%), Positives = 122/308 (39%), Gaps = 32/308 (10%)
Query: 94 EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGV 152
E + G S S H SG+ G GQ G+ G++ +G+ + SS S+ G G
Sbjct: 1641 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSRSSSRYGQHG------ 1693
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
+GS S + RQ Q SP G + + G+ + R P
Sbjct: 1694 ------SGSRQSSGHGRQGSGSGQ---SPSRGRHG-SGLGHSSSHGQHGSGSGRSSSRGP 1743
Query: 213 QTREQDRAHQTGETVTGSG-----TQTQAGATQTVEQDSSHQT-GRTSKQTQEATND-QN 265
+ G+ +GSG +Q +G+ Q T G++S QE ++ Q+
Sbjct: 1744 YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQS 1803
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
HG G SQ+S G Q+ + + + + S Q GS S + S +
Sbjct: 1804 SSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGS 1863
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQT------VSHGGAREQGQTQ 378
+ G G ++S + G+TQ +GS H+ + EQ S++ HG + +
Sbjct: 1864 GSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSY 1923
Query: 379 TQPGSGQR 386
Q GSG R
Sbjct: 1924 GQHGSGSR 1931
Score = 63.2 bits (152), Expect = 5e-10
Identities = 95/419 (22%), Positives = 156/419 (37%), Gaps = 34/419 (8%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQN 148
+ G+ S SG SG+ Q G G + +G QH GS H S Q GSR
Sbjct: 2317 QHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQ 2376
Query: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
+ G ++GS+ SSY + S S++ + SG + Q+ G+ +
Sbjct: 2377 SSRGERHGSSSGSS--SSYGQHG-SGSRQSLGHGQHGSG-SGQSPSPSRGRHGSGSGQSS 2432
Query: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH---------------QTGRT 253
P + G +GSG + G ++ SS Q G T
Sbjct: 2433 SYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGST 2492
Query: 254 SKQTQE-----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSH 308
S Q+ A++ Q+ HG G SQ+S G Q+ H Q + + + S
Sbjct: 2493 SGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYG 2552
Query: 309 QTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQTVS 367
+ GS S ++ S + E G G ++S + ++Q +GS H+ Q S++
Sbjct: 2553 RHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQ 2612
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQ-TGASTESGRQEWSSTHPRRCV 426
G + GS + Q + + G Q +G S GR H
Sbjct: 2613 SSRGERHGSSS---GSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHG 2669
Query: 427 TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGITA 483
G G + + G + +V + + G+ H+S S G + S+ + G T+
Sbjct: 2670 QHGSGSGRSSSRG-PYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 2727
Score = 62.8 bits (151), Expect = 7e-10
Identities = 105/452 (23%), Positives = 169/452 (37%), Gaps = 63/452 (13%)
Query: 94 EGACGSQESGSLH-SGASQELGEGQRSGTEVGRAGKGQHY---EGSSHRQSQQGSRGQNR 149
E + G S S H SG+ G GQ G+ G++ +G+ + GSS Q GS +
Sbjct: 1171 ESSSGQSSSYSQHGSGSGHSSGYGQH-GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQS 1229
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
G QG +GS S R Q SG + + R+ + + +
Sbjct: 1230 SGHGRQG--SGSGHSPSRGRHGSGLGHSSSHGQ-HGSGSGRSSSRGPYESRSGHSSVFGQ 1286
Query: 210 RQPQTREQDRAHQTGETVTGSG---TQTQAGAT----QTVEQDSSHQTGRTSKQTQEAT- 261
+ + Q G +GSG +Q Q G+T T +Q+ S TG++S +
Sbjct: 1287 HESGSGHSSAYSQHG---SGSGHFCSQGQHGSTSGQSSTFDQEGS-STGQSSSYGHRGSG 1342
Query: 262 NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT---- 317
+ Q+ G HG G Q+ G + ++ Q + + SS + GS S Q+
Sbjct: 1343 SSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFG 1402
Query: 318 -QESTNGQNRGTEIHGQGRSQTS-----------------------------QAVTGGHT 347
ES++ Q+ G HG G +S Q +G
Sbjct: 1403 HHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQ 1462
Query: 348 QIQAGSHTETVEQDRSQTVS-HGGAREQGQTQTQPGSGQRWMQVSNP-EAGETVPGG--- 402
+ G H Q S + HG Q + + GSG W P E+G + G
Sbjct: 1463 SLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGH 1522
Query: 403 -QAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLH 461
++++G S+ G+ SS H G Q + G+ + + + G+
Sbjct: 1523 RESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASS-GQSSSHGQHGSGSSQ 1581
Query: 462 TSVSSAQGQDAAQS--EEKRGITARELYSYLR 491
+S QG + QS +RG +R+ SY R
Sbjct: 1582 SSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 1613
Score = 62.4 bits (150), Expect = 9e-10
Identities = 96/413 (23%), Positives = 157/413 (38%), Gaps = 31/413 (7%)
Query: 95 GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGV 152
G+ S SG SG+ Q G G +S + +G QH GS H S Q GSR
Sbjct: 912 GSGRSSSSGRHGSGSGQSSGFGHKSSSGQS-SGYTQHGSGSGHSSSYEQHGSRSGQSSRS 970
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQL-SGQTEQTQKAGEGKRN-QTTEMRPER 210
+ G ++GS+ SSY + Q Q SGQ+ + G + Q++ P R
Sbjct: 971 EQHGSSSGSS--SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYR 1028
Query: 211 QPQTREQDRA-------HQTG----ETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQE 259
R H +G E+ +G + + + + Q G TS Q+
Sbjct: 1029 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1088
Query: 260 -----ATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS 314
A++ Q+ HG G SQ+S G Q+ H Q + + + S + GS S
Sbjct: 1089 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1148
Query: 315 TQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS-HTETVEQDRSQTVSHGGARE 373
++ S + E G G ++S + ++Q +GS H+ Q S++
Sbjct: 1149 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGER 1208
Query: 374 QGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQ-TGASTESGRQEWSSTHPRRCVTEGQGD 432
G + GS + Q + + G Q +G S GR H G G
Sbjct: 1209 HGSSS---GSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
Query: 433 RQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQ--SEEKRGITA 483
+ + G + +V + + G+ H+S S G + S+ + G T+
Sbjct: 1266 GRSSSRG-PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTS 1317
Score = 61.6 bits (148), Expect = 2e-09
Identities = 73/326 (22%), Positives = 118/326 (36%), Gaps = 29/326 (8%)
Query: 95 GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154
G+ S G SG+ G G + +G GQH S H S G G T
Sbjct: 564 GSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGH-SSTHGQHG------ST 616
Query: 155 QGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQT 214
GQ++ + Q+ S Q + +Q + G++ + P R
Sbjct: 617 SGQSSSCGQHGATSGQSSSHGQH----------GSGSSQSSRYGQQGSGSGQSPSRGRHG 666
Query: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274
+ + G+ +GSG + G +V +G++S ++ + Q+ G HG G
Sbjct: 667 SDFGHSSSYGQHGSGSGWSSSNGPHGSV-------SGQSSGFGHKSGSGQSSGYSQHGSG 719
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
S +S G Q+ Q + + S Q GS S Q ++G R G
Sbjct: 720 SSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQ----SSGHGRQGSGSGHS 775
Query: 335 RSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPE 394
S+ + GH+ + T G + G Q + GSGQ + Q +
Sbjct: 776 PSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHGSAS 835
Query: 395 AGETVPGGQAQT-GASTESGRQEWSS 419
+ G T G S+ SG+ + SS
Sbjct: 836 GHFSSQGRHGSTSGQSSSSGQHDSSS 861
Score = 61.6 bits (148), Expect = 2e-09
Identities = 97/414 (23%), Positives = 149/414 (35%), Gaps = 65/414 (15%)
Query: 94 EGACGSQES--GSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151
EG+ Q S G SG+SQ GQ+ +G+H GS H S G G
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH-SSSYGQHG----- 2319
Query: 152 VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
+GS W SS R Q S Q SG T+ +G + + E
Sbjct: 2320 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQ 2369
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
R Q+ +R H + + S Q +G+ Q++ Q G S Q+ + +
Sbjct: 2370 HGSRSGQSSRGER-HGSSSGSSSSYGQHGSGSRQSL---GHGQHGSGSGQSPSPSRGR-- 2423
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
HG G Q+S ++ +G+ + E S H +G +ES +GQ+
Sbjct: 2424 ----HGSGSGQSS-----SYSPYGSGSGWSSSRGPYESGSGHSSG---LGHRESRSGQSS 2471
Query: 327 G----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
G + HGQ S + Q+ + G +G + + + S G R+
Sbjct: 2472 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 2531
Query: 377 TQTQPGSGQRWM-QVSNPE-------AGETVPGGQAQTGASTES--GRQEWSSTHPRRCV 426
+ PG GQR +P +G + GQ +G S G E SS
Sbjct: 2532 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 2591
Query: 427 TEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
G G + G+ SR R ++ + SS GQ + S + G
Sbjct: 2592 QHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSG 2641
Score = 60.8 bits (146), Expect = 3e-09
Identities = 97/395 (24%), Positives = 143/395 (36%), Gaps = 62/395 (15%)
Query: 90 SESAEGACGSQESGSLH--------SGASQELGEGQR-SGT----EVGRAGKGQHYEGSS 136
S + G ES S H SG+ Q G GQR SG+ GR G G SS
Sbjct: 860 SSGQSSSYGQHESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSS 919
Query: 137 HR----QSQQGSRGQNRPGVQTQG---QATGSAWVSSYDRQAESQSQERISPQI-QLSGQ 188
R Q G Q+ G +GS SSY++ Q S Q SG
Sbjct: 920 GRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGS 979
Query: 189 TEQTQKAGEGKRNQT----------TEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA 238
+ + G G R P R ++ G +GSG + G
Sbjct: 980 SSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRG- 1038
Query: 239 TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTP 298
E S H +G + E+ + Q+ G HG +S G Q+ + Q
Sbjct: 1039 --PYESGSGHSSGLGHR---ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 1093
Query: 299 TQTVEQDSSHQTGSTSTQT-----QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353
+ + S Q GS S+Q+ Q S +GQ+ G HGQ S + Q+ + G +G
Sbjct: 1094 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPG---HGQRGSGSRQSPSYGRHGSGSGR 1150
Query: 354 HTETVEQ-----DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQ--AQT 406
+ + + + S H + Q + +Q GSG +G + GQ +++
Sbjct: 1151 SSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSG----------SGHSSGYGQHGSRS 1200
Query: 407 GASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEE 441
G S+ R SS G G RQ + G +
Sbjct: 1201 GQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQ 1235
Score = 60.8 bits (146), Expect = 3e-09
Identities = 98/415 (23%), Positives = 144/415 (34%), Gaps = 67/415 (16%)
Query: 94 EGACGSQES--GSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPG 151
EG+ Q S G SG+SQ GQ+ +G+H GS H S G G
Sbjct: 1796 EGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGH-SSSYGQHG----- 1849
Query: 152 VQTQGQATGSAWVSSYDRQAESQSQ-----ERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
+GS W SS R Q S Q SG T+ +G + + E
Sbjct: 1850 -------SGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSG---HSSSYEQ 1899
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH-QTGRTSKQTQEATNDQN 265
R Q+ R Q G + S + Q G+ Q H Q G S Q+ + +
Sbjct: 1900 HGSRSGQS---SRGEQHGSSSGSSSSYGQHGSGS--RQSLGHGQHGSGSGQSPSPSRGR- 1953
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
HG G Q+S + +G+ + E S H +G +ES +GQ+
Sbjct: 1954 -----HGSGSGQSS-----SYGPYGSGSGWSSSRGPYESGSGHSSG---LGHRESRSGQS 2000
Query: 326 RG----------TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQG 375
G + HGQ S + Q+ + G +G + + + S G R+
Sbjct: 2001 SGYGQHGSSSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGS 2060
Query: 376 QTQTQPGSGQRWM-QVSNPEAGETVPGGQAQT---------GASTESGRQEWSSTHPRRC 425
+ PG GQR +P G G + G S+ G E SS
Sbjct: 2061 GSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSY 2120
Query: 426 VTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
G G + G+ SR R ++ + SS GQ + S + G
Sbjct: 2121 SQHGSGSGHSSGYGQH----GSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSG 2171
Score = 59.7 bits (143), Expect = 6e-09
Identities = 94/416 (22%), Positives = 149/416 (35%), Gaps = 28/416 (6%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
S + G SGS S G G GR G G + SSH Q GS G++
Sbjct: 2152 SSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH-SSSHGQHGSGS-GRS- 2208
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
++G + SS Q ES S + SG + G + + +
Sbjct: 2209 ---SSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQ 2265
Query: 210 RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269
T + Q G + S + Q G+ S Q+ + + + + G
Sbjct: 2266 EGSSTGQSSSHGQHGSGSSQSSSYGQQGS-------GSGQSPSRGRHGSGSGHSSSYGQH 2318
Query: 270 THGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQE---STNGQNR 326
G G S +S G Q H ++ + + H +GS + + E S +GQ+
Sbjct: 2319 GSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSS 2378
Query: 327 GTEIHGQGRSQTS---QAVTGGHTQIQAGSHTETVEQDRSQTVS-HGGAREQGQTQTQPG 382
E HG +S Q +G + G H Q S + HG Q + + G
Sbjct: 2379 RGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYG 2438
Query: 383 SGQRWMQVSNP-EAGETVPGG----QAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTV 437
SG W P E+G G ++++G S+ G+ SS H G Q +
Sbjct: 2439 SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 2498
Query: 438 VGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS--EEKRGITARELYSYLR 491
G+ + + + G+ +S QG + QS +RG +R+ SY R
Sbjct: 2499 CGQHGASS-GQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR 2553
Score = 58.5 bits (140), Expect = 1e-08
Identities = 89/408 (21%), Positives = 144/408 (35%), Gaps = 34/408 (8%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
S G+ S G SG+ G G R +G GQH S H S G G
Sbjct: 2435 SPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGH-SSTHGQHGSTS 2493
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
+ GQ S+ SS Q S S + Q SG Q G G+R + P
Sbjct: 2494 GQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG---SGQSPGHGQRGSGSRQSPS 2550
Query: 210 RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQNRGT 268
R+ +G+ +G G + G ++ +G++S +Q + + + G
Sbjct: 2551 YGRHGSGSGRSSSSGQHGSGLGESSGFGHHES-------SSGQSSSYSQHGSGSGHSSGY 2603
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-QESTNGQNRG 327
HG Q+S+ G + + + Q + + + + GS S Q+ +G G
Sbjct: 2604 GQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLG 2663
Query: 328 -TEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSG-- 384
+ HGQ S + ++ + G + + G H+ Q S G +Q GSG
Sbjct: 2664 HSSSHGQHGSGSGRSSSRGPYESRLG-HSSVFGQHES-----GSGHSSAYSQHGSGSGHF 2717
Query: 385 -QRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWV 443
+ S T + TG S+ G + S+ G G Q G
Sbjct: 2718 CSQGQHGSTSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGS 2777
Query: 444 DDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARELYSYLR 491
Q + + S GQ + S+ G + ++ YSY +
Sbjct: 2778 GS----------GQSSSYGQHGSGSGQSSGYSQHGSG-SGQDGYSYCK 2814
Score = 56.6 bits (135), Expect = 5e-08
Identities = 93/410 (22%), Positives = 148/410 (36%), Gaps = 52/410 (12%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSH--RQSQQGSRGQNRPGVQTQG 156
S G S + Q GQ T + GQH GSS R QQGS P G
Sbjct: 607 SSTHGQHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHG 666
Query: 157 QATGSAWVSSYDRQAESQSQERIS-PQIQLSGQTEQT-QKAGEGKRNQTTEMRPERQPQT 214
G + SSY + + P +SGQ+ K+G G+ + ++
Sbjct: 667 SDFGHS--SSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQ--------- 715
Query: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274
+H +G GS ++G + EQ S +S + + Q+ G G G
Sbjct: 716 HGSGSSHSSGYRKHGS----RSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGRQGSG 771
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ---ESTNGQNRGTEIH 331
+ V G + + +H Q + T S S S Q + +G +G H
Sbjct: 772 SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH 831
Query: 332 G--------QGR--SQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQP 381
G QGR S + Q+ + G +G + + + + + G R + P
Sbjct: 832 GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSP 891
Query: 382 GSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEE 441
G GQR +G++ G+ +G SGR S H G G Q + G +
Sbjct: 892 GHGQR-----GSGSGQSPSYGRHGSG----SGRSSSSGRH-------GSGSGQSSGFGHK 935
Query: 442 WVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS--EEKRGITARELYSY 489
+ + + G+ H+S G + QS E+ G ++ SY
Sbjct: 936 --SSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSY 983
Score = 56.2 bits (134), Expect = 7e-08
Identities = 97/401 (24%), Positives = 154/401 (38%), Gaps = 46/401 (11%)
Query: 90 SESAEGACGSQESG--SLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
S G+ SQ SG SG+ Q G GQR G+H GS + S GQ
Sbjct: 1101 SHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS----GRSSSSGQ 1156
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGE---GKRNQTT 204
+ G+ G+++G S Q+ S SQ S SG + ++G+ G+R+ ++
Sbjct: 1157 HGSGL---GESSGFGHHESSSGQSSSYSQHG-SGSGHSSGYGQHGSRSGQSSRGERHGSS 1212
Query: 205 EMRPERQPQTREQDR-AHQTGETVTGSGTQTQAGATQT-VEQDSSH-QTGRTSKQTQEAT 261
Q R + G +GSG G + + SSH Q G S ++
Sbjct: 1213 SGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRG 1272
Query: 262 NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGT-HTQTPTQTVEQDSSHQTGSTSTQTQE- 319
++R + G+ ++ + ++Q +G+ H + Q +G +ST QE
Sbjct: 1273 PYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ-----HGSTSGQSSTFDQEG 1327
Query: 320 STNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQT 379
S+ GQ+ G G SQ+S G+ + AGS ++ + R HG +
Sbjct: 1328 SSTGQSSSYGHRGSGSSQSS-----GYGRHGAGS-GQSPSRGR-----HGSGSGHSSSYG 1376
Query: 380 QPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVG 439
Q GSG W S + +G S+ G E SS C G G
Sbjct: 1377 QHGSGSGWSSSSGRHG--------SGSGQSSGFGHHESSSWQSSGCTQHGSGSGH----S 1424
Query: 440 EEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
+ SR R ++ + SS+ GQ + S + G
Sbjct: 1425 SSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLG 1465
Score = 55.8 bits (133), Expect = 9e-08
Identities = 88/404 (21%), Positives = 149/404 (36%), Gaps = 61/404 (15%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGK-GQHYEGSSHRQS--------- 140
+ G+ S G SG+ Q G R G++ G + GQH GS S
Sbjct: 638 QHGSGSSQSSRYGQQGSGSGQSPSRG-RHGSDFGHSSSYGQHGSGSGWSSSNGPHGSVSG 696
Query: 141 QQGSRGQNRPGVQTQG---QATGSAWVSSY----DRQAESQSQERISPQIQLSGQTEQ-- 191
Q G Q+ G +GS+ S Y R +S E+ LS Q
Sbjct: 697 QSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQHGSSSGLSSSYGQHG 756
Query: 192 ---TQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSS- 247
Q +G G++ + P R + G+ +G+ + G ++ +S
Sbjct: 757 SGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASG 816
Query: 248 ---HQTGRTSKQTQEAT-----NDQNRGTETHGQ----GRSQTSQAVTGGHAQIQAGTHT 295
H++G +Q + + Q R T GQ G+ +S + + Q ++ +H
Sbjct: 817 FGQHESGSGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHH 876
Query: 296 QT-----PTQTVEQDSSHQTGSTSTQTQE-----STNGQNRGTEIHGQGRSQ-------T 338
+ + + + Q GS S Q+ S +G++ + HG G Q +
Sbjct: 877 ASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKS 936
Query: 339 SQAVTGGHTQIQAGS-HTETVEQ------DRSQTVSHGGAREQGQTQTQPGSGQRWMQVS 391
S + G+TQ +GS H+ + EQ S++ HG + + Q GSG R +
Sbjct: 937 SSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSR-QSLG 995
Query: 392 NPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQP 435
+ + G + + SG + SS P R + R P
Sbjct: 996 HGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGP 1039
Score = 54.7 bits (130), Expect = 2e-07
Identities = 90/417 (21%), Positives = 143/417 (34%), Gaps = 51/417 (12%)
Query: 97 CGSQESGSLHSGASQELGE-------GQRSGTEVGRA--------------GKGQHYEGS 135
C SGS HS + ++ G G+R G+ G + G GQH GS
Sbjct: 1414 CTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGS 1473
Query: 136 SHRQSQQGSRGQNRPGVQTQGQ----ATGSAWVSSY-DRQAESQSQERISPQIQLSGQTE 190
QS SRG++ G +GS W SS ++ S + + SGQ+
Sbjct: 1474 G--QSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSHSSGLGHRESRSGQSS 1531
Query: 191 QTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTV----EQDS 246
+ G + +T + H + S Q +G++Q+ +
Sbjct: 1532 GYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSG 1591
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
S Q+ ++ + + G G GRS +S G + H ++ + S
Sbjct: 1592 SGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYS 1651
Query: 307 SHQTGSTSTQ---TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRS 363
H +GS + S +GQ+ E HG +S+ G Q+ H
Sbjct: 1652 QHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQ-GSGSG 1710
Query: 364 QTVS---HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
Q+ S HG + Q GSG P ++++G S+ G+ E S
Sbjct: 1711 QSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPY--------ESRSGHSSVFGQHESGSG 1762
Query: 421 HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEE 477
H G G G+ T DQ T SS+ GQ + S +
Sbjct: 1763 HSSAYSQHGSGSGHFCSQGQHGSTSGQSST----FDQEGSSTGQSSSHGQHGSGSSQ 1815
Score = 53.9 bits (128), Expect = 3e-07
Identities = 85/372 (22%), Positives = 126/372 (33%), Gaps = 37/372 (9%)
Query: 92 SAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ-----SQQGSRG 146
S + G Q SGS S + G G + G+ G G + SS R G
Sbjct: 2284 SQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGH 2343
Query: 147 QNRPGVQTQG---QATGSAWVSSYDRQAESQSQ-ERISPQIQLSGQTEQTQKAGEGKRNQ 202
Q+ G +GS SSY++ Q R SG + + G G R
Sbjct: 2344 HESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHGSGSRQS 2403
Query: 203 T----------TEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSS---HQ 249
P R ++ +GSG + G ++ SS H+
Sbjct: 2404 LGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHR 2463
Query: 250 TGRTSKQTQEATNDQNRG-TETHGQGRS---QTSQAVTGGHAQIQAGTHTQTPTQTVEQD 305
R+ + + + + G + THGQ S Q+S G + Q+ +H Q + + +
Sbjct: 2464 ESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSS 2523
Query: 306 SSHQTGSTSTQT-------QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ GS S Q+ S + G G GRS +S G + H E+
Sbjct: 2524 GYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESS 2583
Query: 359 EQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWS 418
S HG G + G R Q S E + G + G RQ S
Sbjct: 2584 SGQSSSYSQHGSG--SGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQ--S 2639
Query: 419 STHPRRCVTEGQ 430
S H R+ GQ
Sbjct: 2640 SGHGRQGSGSGQ 2651
Score = 53.5 bits (127), Expect = 4e-07
Identities = 86/402 (21%), Positives = 136/402 (33%), Gaps = 32/402 (7%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
S S + + G Q S S +S GQ G GQH GS QS SRG++
Sbjct: 1902 SRSGQSSRGEQHGSSSGSSSSY----GQHGSGSRQSLGHGQHGSGSG--QSPSPSRGRHG 1955
Query: 150 PGVQTQGQ----ATGSAWVSSY-DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTT 204
G +GS W SS ++ S + + SGQ+ + G + +T
Sbjct: 1956 SGSGQSSSYGPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSST 2015
Query: 205 EMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTV----EQDSSHQTGRTSKQTQEA 260
+ H + S Q +G++Q+ + S Q+ ++ +
Sbjct: 2016 HGQHGSASGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGS 2075
Query: 261 TNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQ---T 317
+ G G GRS +S G + H ++ + S H +GS +
Sbjct: 2076 RQSPSYGRHGSGSGRSSSSGQHGPGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ 2135
Query: 318 QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE--TVEQDRSQTVSHGGAREQG 375
S +GQ+ E HG +S+ G Q+ H + HG
Sbjct: 2136 HGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGHS 2195
Query: 376 QTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQP 435
+ Q GSG P ++++G S+ G+ E S H G G
Sbjct: 2196 SSHGQHGSGSGRSSSRGPY--------ESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHF 2247
Query: 436 TVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEE 477
G+ T DQ T SS+ GQ + S +
Sbjct: 2248 CSQGQHGSTSGQSST----FDQEGSSTGQSSSHGQHGSGSSQ 2285
Score = 51.6 bits (122), Expect = 2e-06
Identities = 67/278 (24%), Positives = 103/278 (37%), Gaps = 30/278 (10%)
Query: 95 GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGV 152
G+ S SG SG + G G + + QH GS H Q GSR
Sbjct: 2557 GSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRG 2616
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK----------AGEGKRNQ 202
+ G ++GS SS+ Q S S++ Q SG + + + G+
Sbjct: 2617 ERHGSSSGS---SSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGS 2673
Query: 203 TTEMRPERQPQTREQDRAHQTGETVTGSG-----TQTQAGATQTVEQDSSHQT-GRTSKQ 256
+ R P + G+ +GSG +Q +G+ Q T G++S
Sbjct: 2674 GSGRSSSRGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTF 2733
Query: 257 TQEATNDQNRGTETH-GQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTST 315
QE ++ + H G G SQ+S G Q+ +H + + + + S Q GS S
Sbjct: 2734 DQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYGQHGSGS- 2792
Query: 316 QTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353
GQ+ G HG G Q + G + GS
Sbjct: 2793 -------GQSSGYSQHGSGSGQDGYSYCKGGSNHDGGS 2823
Score = 48.9 bits (115), Expect = 1e-05
Identities = 92/414 (22%), Positives = 139/414 (33%), Gaps = 46/414 (11%)
Query: 98 GSQESGSLHSGASQELGEGQRSGTEVGRAGKGQH--YEGSSHRQSQQGSRGQNRPGVQTQ 155
G S S HS GQ T + GQH G S Q GS G Q
Sbjct: 1064 GQHGSSSGHSST-----HGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQ 1118
Query: 156 ----GQATGSAWVSSYDRQAESQSQERI-SPQIQLSGQ--TEQTQKAGEGKRNQTTEMRP 208
GQ+ G S RQ+ S + S + SGQ + + +G G ++
Sbjct: 1119 GSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSS 1178
Query: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH--QTGRTSKQTQEATNDQNR 266
+ G+ + SG ++ + SSH Q G S+Q+ +
Sbjct: 1179 SYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSG 1238
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
+ +GR + + H Q +G+ + E S H S+ ES +G +
Sbjct: 1239 SGHSPSRGRHGSGLGHSSSHGQHGSGSGRSSSRGPYESRSGH---SSVFGQHESGSGHSS 1295
Query: 327 GTEIHGQGR----SQTSQAVTGGHTQI--QAGSHTETVEQDRSQTVSH---GGAREQGQT 377
HG G SQ T G + Q GS T +S + H G ++ G
Sbjct: 1296 AYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST-----GQSSSYGHRGSGSSQSSGYG 1350
Query: 378 QTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTV 437
+ GSGQ +P G G + WSS+ R GQ
Sbjct: 1351 RHGAGSGQ------SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHH 1404
Query: 438 VGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSE--EKRGITARELYSY 489
W + + + G+ H+S G + QS E+ G ++ SY
Sbjct: 1405 ESSSW-----QSSGCTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSY 1453
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 116 bits (291), Expect = 4e-26
Identities = 118/453 (26%), Positives = 179/453 (39%), Gaps = 43/453 (9%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M LL+++ +I+ F +Y + +G C L++GELK LLE+E V+ P DP TVD ++ +
Sbjct: 1 MTDLLRSVVTVIDVFYKYTKQDGECGTLSKGELKELLEKELHPVLKNPDDPDTVDVIMHM 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
LD DH ++F EFL+++FK+ AC K LS+ A GS++ H +E +
Sbjct: 61 LDRDHDRRLDFTEFLLMIFKLTMACNKVLSKEYCKASGSKKHRRGHRHQEEESETEEDEE 120
Query: 121 TEVGRAGKGQH---YEGSSHRQSQQGSRG--QNRPGVQTQGQATGSAWVSSYDRQAESQS 175
G +H EG H S SRG + R G ++ SS +++ +
Sbjct: 121 DTPGHKSGYRHSSWSEGEEHGYSSGHSRGTVKCRHGSNSRRLGRQGNLSSSGNQEGSQKR 180
Query: 176 QERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ 235
R S SG G+ + ++ ER ++ E +GSG+ +
Sbjct: 181 YHRSSCGHSWSG--------GKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSW 232
Query: 236 AGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHT 295
+G S TQ +Q G+ G G S G G
Sbjct: 233 ERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGSGDSGRRSHACGYSNSSGCG--- 289
Query: 296 QTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHT 355
P SH+ G Q +G G + GQG V+GG Q
Sbjct: 290 -RPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIK-GGQGHG----CVSGG--QPSGCGQP 341
Query: 356 ETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEA--GETVPGGQAQTGASTESG 413
E+ +S + GARE GQ Q G +W S+ + G+ GG S +G
Sbjct: 342 ESNPCSQSYSQRGYGARENGQPQ---NCGGQWRTGSSQSSCCGQYGSGG----SQSCSNG 394
Query: 414 RQEW----------SSTHPRRCVTEGQGDRQPT 436
+ E+ SS +C G G Q T
Sbjct: 395 QHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQST 427
Score = 77.4 bits (189), Expect = 3e-14
Identities = 95/353 (26%), Positives = 141/353 (39%), Gaps = 35/353 (9%)
Query: 103 GSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGVQTQGQATG 160
G SG+SQ G GQ +G GQH GS Q GS G G TG
Sbjct: 1077 GQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTG 1136
Query: 161 --SAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGE----GKRNQTTEMRPERQPQT 214
S + R +S + + Q SG + +G G+ ++
Sbjct: 1137 KSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHI 1196
Query: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETH--- 271
+ ++ G+ +GSG T G ++ + +S G T QE T+ Q T H
Sbjct: 1197 SDSGQSTGFGQYGSGSGQSTGLGQGESQQVES----GSTVHGRQETTHGQTINTTRHSQS 1252
Query: 272 GQGRS-QTSQAVTGGHAQIQA-GTHTQTPTQTVEQDSSH----------QTGSTSTQTQE 319
GQG+S QT VT Q+ + ++ ++ + S H ++GST + Q
Sbjct: 1253 GQGQSTQTGSRVTRRRRSSQSENSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQG 1312
Query: 320 STNGQNRGTEIHG-QGRSQTSQAVTGGHTQ-IQAGSHTETVEQDRSQTVSHGGAREQGQT 377
+T+GQ T HG G Q++Q TG T Q SH++ + + VSH Q QT
Sbjct: 1313 TTHGQRGDTTRHGHSGHGQSTQ--TGSRTSGRQRFSHSDATDSEVHSGVSH-RPHSQEQT 1369
Query: 378 QTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQ 430
+Q GS + + E ET G QTG +T G + R T G+
Sbjct: 1370 HSQAGSQHGESESTVHERHETTYG---QTGEATGHGHSGHGQSTQRGSRTTGR 1419
Score = 72.0 bits (175), Expect = 1e-12
Identities = 103/402 (25%), Positives = 147/402 (36%), Gaps = 60/402 (14%)
Query: 117 QRSGTEVGRAGKGQHYEGSSHRQSQQ-GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQS 175
+R GT G+ G + S H QS Q GSR R + AT S S + SQ
Sbjct: 1309 RRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRF-SHSDATDSEVHSGVSHRPHSQE 1367
Query: 176 QERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ 235
Q Q G++E T +R++TT QT E TG +G G TQ
Sbjct: 1368 QTHSQAGSQ-HGESESTVH----ERHETT------YGQTGEA-----TGHGHSGHGQSTQ 1411
Query: 236 AGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQ---TSQAVTGGHAQIQAG 292
G+ T + S H S+ ++ +THGQ SQ + V G H
Sbjct: 1412 RGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESGSTVHGRHGTTHGQ 1471
Query: 293 THTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAG 352
T T S Q GS++T + S + ++ +E+H G S GHT Q+G
Sbjct: 1472 TGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGSHTHS-----GHTHGQSG 1526
Query: 353 S---HTETVEQDRSQTV----------SHGGAREQGQTQTQPGSGQRWMQVSNPEA---- 395
S +E++ DR + S+ G + QT ++ QR + ++
Sbjct: 1527 SQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTGSRTTGRQRTSHSESTDSEVHS 1586
Query: 396 -GETVPGGQAQTGASTESGRQEWSST-HPRRCVTEGQ----------GDRQPTVVGEEWV 443
G P + T S +E T H R T GQ G Q T G
Sbjct: 1587 GGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQRGSRTT 1646
Query: 444 ----DDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGI 481
HS E+ + G HT GQ +Q + I
Sbjct: 1647 GRQRSSHS-ESSDSEVHSGVSHTHTGHTHGQAGSQHGQSESI 1687
Score = 72.0 bits (175), Expect = 1e-12
Identities = 95/370 (25%), Positives = 140/370 (37%), Gaps = 44/370 (11%)
Query: 93 AEGACGSQE--SGSLHSGASQELGEG-----QRSGTEVGRAGKGQHYEGSSHRQS-QQGS 144
+EG G SG H A E +R GT G+ + S H QS Q+GS
Sbjct: 1961 SEGPSGVSHTHSGHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHGHSGHGQSTQRGS 2020
Query: 145 R--GQNRPGVQTQGQATGSAWVSSYDR-----QAESQSQERISPQIQ----LSGQTEQTQ 193
R G+ G + G + VS QA SQ E S + GQT T
Sbjct: 2021 RTTGRRASGHSEYSDSEGHSGVSHTHSGHAHGQAGSQHGESGSSVHERHGTTHGQTGDTT 2080
Query: 194 KAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRT 253
+ Q+T+ R R R + + V + T +G T + ++G
Sbjct: 2081 RHAHSGHGQSTQ-RGSRTAGRRGSGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSA 2139
Query: 254 SKQTQEATNDQNRGTETHGQ-GRSQTSQAVTGGHAQ-IQAGTHTQTPTQTVEQDSS-HQT 310
Q + Q T HGQ G Q++Q TG Q +H+++ V ++S +
Sbjct: 2140 IHGRQGTIHGQTGDTTRHGQSGHGQSTQ--TGSRTTGRQRSSHSESSDSEVHSEASPTHS 2197
Query: 311 GSTSTQT-----QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE------TVE 359
G T +Q Q ++G R HGQ T A G Q GS T E
Sbjct: 2198 GHTHSQAGSRHGQSGSSGHGRQGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSE 2257
Query: 360 QDRSQTVSHGGAREQGQTQTQPGSGQRW--------MQVSNPEAGETVPGGQAQTGASTE 411
S+ S G G Q Q GS QR ++ ++ + G+T G + G ST+
Sbjct: 2258 SSDSEVHSWGSHTHSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQ 2317
Query: 412 SGRQEWSSTH 421
+G + ++H
Sbjct: 2318 TGSRSSRASH 2327
Score = 70.9 bits (172), Expect = 3e-12
Identities = 104/446 (23%), Positives = 156/446 (34%), Gaps = 76/446 (17%)
Query: 98 GSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQ 157
GS+ +G S S+ SG G GS H QS+ S R G T GQ
Sbjct: 1642 GSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSE--SIVPERHGT-THGQ 1698
Query: 158 ATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQ 217
+ + Y +Q+ R + + + SG +E + G + T Q +++
Sbjct: 1699 TGDTTRHAHYHHGLTTQTGSRTTGR-RGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHG 1757
Query: 218 DRAH-----------QTGETV----TGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATN 262
+ QTG+T +G G TQ G+ T + S H S+ +
Sbjct: 1758 ESESIVHERHGTIHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQ 1817
Query: 263 DQNRGTETHGQGRSQTSQAV----------------TGGHAQIQAGTHTQTPTQTVEQDS 306
+ THGQ SQ ++ T GH+Q G TQ+ + T +
Sbjct: 1818 RPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQSGHGQSTQSGSSTTGRRR 1877
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGH-----TQIQAGSHTETVEQD 361
S + S+ ++ + + G H Q RSQ ++ + H T Q G TE
Sbjct: 1878 SGHSESSDSEVHSGGSHTHSG-HTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPS 1936
Query: 362 RSQTVSHG----GAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGAS-TESGRQE 416
QT+ G G R G ++ G VS+ +G T Q G+ ESG
Sbjct: 1937 HGQTIQTGSRTTGRRGSGHSEYSDSEGP--SGVSHTHSGHT----HGQAGSHYPESG--- 1987
Query: 417 WSSTHPRRCVTEGQ----------GDRQPT----------VVGEEWVDDHSRETVILRLD 456
SS H R T GQ G Q T G D + +
Sbjct: 1988 -SSVHERHGTTHGQTADTTRHGHSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTH 2046
Query: 457 QGNLHTSVSSAQGQDAAQSEEKRGIT 482
G+ H S G+ + E+ G T
Sbjct: 2047 SGHAHGQAGSQHGESGSSVHERHGTT 2072
Score = 67.0 bits (162), Expect = 4e-11
Identities = 95/370 (25%), Positives = 141/370 (38%), Gaps = 59/370 (15%)
Query: 94 EGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPG 151
E G SG+SQ G GQ + G GQH S Q GS G
Sbjct: 991 ESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSG 1050
Query: 152 VQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQ 211
G +G SS Q ES+S++ Q SG ++ + G + T + +
Sbjct: 1051 FGQHGTGSGQ---SSGFGQYESRSRQSSYGQ-HGSGSSQSSGYGQHGSNSGQTSGFGQHR 1106
Query: 212 PQTREQDRAHQTGETVT--------GSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATND 263
P + + Q G GSGT +G Q +++G++S +
Sbjct: 1107 PGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQ-----HEYRSGQSSYGQHGTGSS 1161
Query: 264 QNRGTETHGQGRSQTS---QAVTGGHAQIQAGTHTQTPTQT---------------VEQD 305
Q+ G H G T+ Q V+G +G H Q+ + Q
Sbjct: 1162 QSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQSTGLGQG 1221
Query: 306 SSHQ--TGSTSTQTQESTNGQNRGTEIHGQ-GRSQTSQAVTGGH-TQIQAGSHTETVEQD 361
S Q +GST QE+T+GQ T H Q G+ Q++Q TG T+ + S +E + +
Sbjct: 1222 ESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQ--TGSRVTRRRRSSQSENSDSE 1279
Query: 362 RSQTVSHGGAREQGQTQTQPGSG--------QRWMQVSNPEAGETVPGGQAQTGASTE-- 411
VSH R TQ GS +R ++ + G+T G + G ST+
Sbjct: 1280 VHSKVSH---RHSEHIHTQAGSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTG 1336
Query: 412 ---SGRQEWS 418
SGRQ +S
Sbjct: 1337 SRTSGRQRFS 1346
Score = 64.7 bits (156), Expect = 2e-10
Identities = 95/404 (23%), Positives = 140/404 (34%), Gaps = 37/404 (9%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ-SQQGSRGQNR 149
+ G+ S G SG+ Q G GQ +G GQH S H Q G
Sbjct: 644 QHGSGSSQSTGFGQYGSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQS 703
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQI-QLSGQTEQTQKAGEGKRNQTTEMRP 208
G G ++G S + + S Q Q SGQ+ + G G Q++
Sbjct: 704 SGYGQHGSSSGQ--TSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGS-GQSSGFGQ 760
Query: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGT 268
+ H +G + + Q + T Q S + T + + Q+ G
Sbjct: 761 HESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGF 820
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ----TVEQDSSHQTGSTSTQT-----QE 319
HG G Q+S G Q ++ +H + Q + + Q GS+S QT
Sbjct: 821 GQHGSGSGQSS-----GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGFGQHR 875
Query: 320 STNGQNRGTEIHGQGRSQTS---QAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
S++GQ G HG G Q+S Q TG G H Q S HG Q
Sbjct: 876 SSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQ--SSYGQHGSGSSQSS 933
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
Q GS +G+T GQ ++G+ SG + S + + G G +
Sbjct: 934 GYGQHGS----------SSGQTFGFGQHRSGSGQSSGFGQHGSGSGQ---SSGFGQHESG 980
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRG 480
H + Q +S SS GQ + S + G
Sbjct: 981 SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSGQTTG 1024
Score = 63.5 bits (153), Expect = 4e-10
Identities = 105/411 (25%), Positives = 150/411 (36%), Gaps = 38/411 (9%)
Query: 95 GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQS--QQGSRGQNRPGV 152
G+ S G SG+ Q G GQ G++ GQH GSS Q GSR + G
Sbjct: 586 GSGQSSGFGQHGSGSGQSSGFGQHESRS-GQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQ 644
Query: 153 QTQG--QATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPER 210
G Q+TG S Q+ Q +S Q SG + ++G Q +
Sbjct: 645 HGSGSSQSTGFGQYGSGSGQSSGFGQH-VSGSGQSSGFGQHESRSGHSSYGQHGFGSSQS 703
Query: 211 QPQTREQDRAHQT---GETVTGSGTQTQAGATQTVEQDSSH--QTGRTSKQTQEATNDQN 265
+ + QT G+ SG + G + SS Q G S Q+ ++
Sbjct: 704 SGYGQHGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSGFGQHES 763
Query: 266 R-GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQ 324
R G ++GQ S +SQ+ G+ Q H T Q S + ST S +GQ
Sbjct: 764 RSGQSSYGQHSSGSSQS--SGYGQ-----HGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQ 816
Query: 325 NRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQ-PGS 383
+ G HG G Q+S G Q ++ SH + Q S + G + G + Q G
Sbjct: 817 SAGFGQHGSGSGQSS-----GFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSSGQTSGF 871
Query: 384 GQRWMQVS--------NPEAGETVPGGQAQTGASTESG-RQEWSSTHPRRCVTEGQGDRQ 434
GQ +G++ GQ TG+ SG Q S +H G G Q
Sbjct: 872 GQHRSSSGQYSGFGQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQ 931
Query: 435 PTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITARE 485
+ G+ S Q + SS GQ + S + G E
Sbjct: 932 SSGYGQH----GSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHE 978
Score = 61.2 bits (147), Expect = 2e-09
Identities = 95/427 (22%), Positives = 139/427 (32%), Gaps = 75/427 (17%)
Query: 101 ESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATG 160
++GS H E +R GT G+ G + S H QS Q RG G Q
Sbjct: 1601 QAGSQHE--EPEFTVHERHGTTHGQIGDTTGHSHSGHGQSTQ--RGSRTTGRQR------ 1650
Query: 161 SAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQD-- 218
SS+ ++S+ +S T T + Q+ + PER T Q
Sbjct: 1651 ----SSHSESSDSEVHSGVSHT-----HTGHTHGQAGSQHGQSESIVPERHGTTHGQTGD 1701
Query: 219 -----RAHQTGETVTGSGTQTQAGATQTVEQDS-------------SHQTGRTSKQTQEA 260
H T TGS T + G+ + DS +H R+ E+
Sbjct: 1702 TTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSGHTHGQARSQHGESES 1761
Query: 261 TNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQES 320
+ GT HGQ T A +G Q G+ T + + S G + +
Sbjct: 1762 IVHERHGT-IHGQTGDTTRHAHSGHGQSTQTGSRTTGRRSSGHSEYSDSEGHSGFSQRPH 1820
Query: 321 TNGQNRG-------------TEIHGQGRSQTSQAVTGGHTQIQAGSHTET---------- 357
+ G G E HG QT T GH+Q G T++
Sbjct: 1821 SRGHTHGQAGSQHGESESIVDERHGTTHGQTGD--TSGHSQSGHGQSTQSGSSTTGRRRS 1878
Query: 358 --VEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQ 415
E S+ S G G T +Q S + + + +T G QTG +TE G
Sbjct: 1879 GHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHG---QTGDTTEHGHP 1935
Query: 416 EWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
T T G+ G D + + G+ H S + +
Sbjct: 1936 SHGQTIQTGSRTTGRRGS-----GHSEYSDSEGPSGVSHTHSGHTHGQAGSHYPESGSSV 1990
Query: 476 EEKRGIT 482
E+ G T
Sbjct: 1991 HERHGTT 1997
Score = 56.2 bits (134), Expect = 7e-08
Identities = 95/405 (23%), Positives = 141/405 (34%), Gaps = 70/405 (17%)
Query: 87 KTLSESAEGACGSQESG--SLHSGASQELGEGQRSGTEVGRAGKGQHYE--------GSS 136
KT G+ Q SG SG+ Q G GQ +G GQH G
Sbjct: 475 KTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQH 534
Query: 137 HRQSQQGSRGQNRPGVQT---------------------QGQATGSAWVSSYDRQAESQS 175
+S+Q S GQ+ G GQ+TG S Q+
Sbjct: 535 ESRSRQSSYGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFG 594
Query: 176 QERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDR------------AHQT 223
Q S Q SG + ++G+ Q + + + R + T
Sbjct: 595 QHG-SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQST 653
Query: 224 GETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVT 283
G GSG+ +G Q V +G++S Q + + HG G SQ+S
Sbjct: 654 GFGQYGSGSGQSSGFGQHVS-----GSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQ 708
Query: 284 GGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQT-----QESTNGQNRGTEIHGQGRSQT 338
G + Q Q + + S Q GS S Q+ S +GQ+ G GQ S++
Sbjct: 709 HGSSSGQTSGFGQHELSSGQSSSFGQHGSGSGQSSGFGQHGSGSGQSSG---FGQHESRS 765
Query: 339 SQAVTGGHT--QIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
Q+ G H+ Q+ + + + S HG Q Q GSG +G
Sbjct: 766 GQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSG----------SG 815
Query: 397 ETVPGGQAQTGASTESG-RQEWSSTHPRRCVTEGQGDRQPTVVGE 440
++ GQ +G+ SG Q S +H G G Q + G+
Sbjct: 816 QSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQ 860
Score = 55.5 bits (132), Expect = 1e-07
Identities = 98/417 (23%), Positives = 149/417 (35%), Gaps = 47/417 (11%)
Query: 90 SESAEGACGSQESGSLHSGASQ---------ELGEGQRSGTEVGRAGKGQHYEGSSHRQS 140
S G+ SQ SG G+S G GQ SG +G GQ H
Sbjct: 921 SYGQHGSGSSQSSGYGQHGSSSGQTFGFGQHRSGSGQSSGFGQHGSGSGQSSGFGQHESG 980
Query: 141 QQGSRG----QNRPGVQTQGQ-ATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKA 195
S G ++R GQ +GS+ S Y + S SGQT
Sbjct: 981 SGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQHGSS------------SGQT-----T 1023
Query: 196 GEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH-QTGRTS 254
G G+ ++ D++ G+ TGSG + G ++ + SS+ Q G S
Sbjct: 1024 GFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGS 1083
Query: 255 KQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS 314
Q+ + +T G G+ + + G Q +G+ + Q S S+
Sbjct: 1084 SQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGS---GQSSGFGQHGSGTGKSSG 1140
Query: 315 TQTQESTNGQNRGTEIHGQGRSQTS---QAVTGGHTQIQAGSHTETVEQDRS--QTVSHG 369
E +GQ+ + HG G SQ+S Q +G G H + S Q +S
Sbjct: 1141 FAQHEYRSGQSSYGQ-HGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNFSSSGQHISDS 1199
Query: 370 GAREQGQTQTQPGSGQR----WMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRC 425
G + G Q GSGQ + E+G TV G Q T T + + S +
Sbjct: 1200 G-QSTGFGQYGSGSGQSTGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQST 1258
Query: 426 VTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGIT 482
T + R+ E D V R + ++HT S + + ++G T
Sbjct: 1259 QTGSRVTRRRRSSQSENSDSEVHSKVSHRHSE-HIHTQAGSHYPKSGSTVRRRQGTT 1314
Score = 49.7 bits (117), Expect = 6e-06
Identities = 76/358 (21%), Positives = 120/358 (33%), Gaps = 45/358 (12%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR------GQNRPGV 152
S S S SG E G G S G G E S H + SR G + G
Sbjct: 211 SHISPSRESGEEYESGSGSNSWERKGHGGLSCGLETSGHESNSTQSRIREQKLGSSCSGS 270
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQ----------KAGEG---- 198
G+ + + S+ Q+ + GQ Q K G+G
Sbjct: 271 GDSGRRSHACGYSNSSGCGRPQNASSSCQSHRFGGQGNQFSYIQSGCQSGIKGGQGHGCV 330
Query: 199 -----------KRNQTTEMRPERQPQTREQDRAH------QTGETVTGSGTQTQAGATQT 241
+ N ++ +R RE + +TG + + Q +G +Q+
Sbjct: 331 SGGQPSGCGQPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGSSQSSCCGQYGSGGSQS 390
Query: 242 VEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAG---THTQTP 298
+ H+ G + + +++++ + +G G SQ++ G Q+ H
Sbjct: 391 CS-NGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGTGLSQSSGFEQHVCGS 449
Query: 299 TQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTS---QAVTGGHTQIQAGSHT 355
QT Q S + S S++G+ G HG G Q+S Q +G G H
Sbjct: 450 GQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQCGSGSGQSSGFGQH- 508
Query: 356 ETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESG 413
+V S HG Q Q S R +G + G Q G+ SG
Sbjct: 509 GSVSGQSSGFGQHGSVSGQSSGFGQHESRSRQSSYGQHGSGSSQSSGYGQYGSRETSG 566
Score = 46.2 bits (108), Expect = 7e-05
Identities = 62/261 (23%), Positives = 93/261 (35%), Gaps = 40/261 (15%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR-GQN 148
S +E + SG H+ + G+ + E G A G+ +G+ H Q+ +R GQ+
Sbjct: 2103 SGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGR--QGTIHGQTGDTTRHGQS 2160
Query: 149 RPGVQTQ-GQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
G TQ G T SS+ ++S+ SP SG T + G+ + R
Sbjct: 2161 GHGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTH--SGHTHSQAGSRHGQSGSSGHGR 2218
Query: 208 PERQPQTREQDRAH-QTGETVT----GSGTQTQAGATQTVEQDSSH-------------- 248
Q H QTG+T G G TQ G+ T + S H
Sbjct: 2219 ---------QGTTHGQTGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSH 2269
Query: 249 ------QTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
Q S+Q Q + R THGQ T +G Q G+ + +
Sbjct: 2270 THSGHIQGQAGSQQRQPGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQ 2329
Query: 303 EQDSSHQTGSTSTQTQESTNG 323
S Q +S + + G
Sbjct: 2330 SHSSERQRHGSSQVWKHGSYG 2350
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 103 bits (258), Expect = 3e-22
Identities = 83/280 (29%), Positives = 130/280 (46%), Gaps = 25/280 (8%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M LL++I I E F +Y + + ALT+ +LK LLE+EF V+ +PHDP TVD +L L
Sbjct: 1 MSPLLRSICDITEIFNQYVSHDCDGAALTKKDLKNLLEREFGAVLRRPHDPKTVDLILEL 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
LD D G V+F EFL+ +FKVAQAC+ L + A G E + L + +R
Sbjct: 61 LDLDSNGRVDFNEFLLFIFKVAQACYYALGQ----ATGLDEEKRARCDGKESLLQDRRQE 116
Query: 121 TEVGR-AGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQS---- 175
+ R + + E ++ +Q + Q R + + Q+ + DRQ +
Sbjct: 117 EDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQ 176
Query: 176 -------QERISPQIQLSG----QTEQTQKAGEGKRNQTTEM----RPERQPQTRE-QDR 219
+ER + + QL +TE+ + +R + E+ R E+Q Q RE QDR
Sbjct: 177 RQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDR 236
Query: 220 AHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQE 259
Q E +T + Q+ Q R ++ +E
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEE 276
Score = 33.1 bits (74), Expect = 0.60
Identities = 42/249 (16%), Positives = 93/249 (37%), Gaps = 20/249 (8%)
Query: 168 DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETV 227
+RQ E Q Q+R+ + QL + E+ ++ + +R + E R E+Q + REQ + E
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERR-EQQEERREQQLRREQEE-- 345
Query: 228 TGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHA 287
+ + + E++ Q R ++ + R + + + + Q +
Sbjct: 346 -----RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR-REQ 399
Query: 288 QIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHT 347
Q++ + Q + + + +E + Q E Q + +
Sbjct: 400 QLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE---RRD 456
Query: 348 QIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTG 407
++ TE EQ+R ++Q + + +RW+++ E E + Q
Sbjct: 457 WLKREEETERHEQER--------RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLR 508
Query: 408 ASTESGRQE 416
E R++
Sbjct: 509 REQEERREQ 517
Score = 29.6 bits (65), Expect = 6.6
Identities = 28/134 (20%), Positives = 53/134 (39%), Gaps = 7/134 (5%)
Query: 168 DRQAESQSQER-ISPQIQLSGQTEQTQ---KAGEGK---RNQTTEMRPERQPQTREQDRA 220
++Q SQ +R + QL + E+ Q + +GK + ++ + Q +E+DR
Sbjct: 1785 EQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQ 1844
Query: 221 HQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQ 280
++ E + E++ + R K +E Q + + H Q SQ
Sbjct: 1845 YRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Query: 281 AVTGGHAQIQAGTH 294
G ++ GTH
Sbjct: 1905 EGKGHGRLLEPGTH 1918
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 103 bits (256), Expect = 5e-22
Identities = 116/476 (24%), Positives = 192/476 (40%), Gaps = 81/476 (17%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M LL+NI II F++Y++ + N L++ ELK LLE+EF ++ P DP VD +
Sbjct: 1 MSTLLENIFAIINLFKQYSKKDKNTDTLSKKELKELLEKEFRQILKNPDDPDMVDVFMDH 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESAEGACGSQESGSLHSGASQELGEGQRSG 120
LD DH ++F EFL++VFK+AQA ++ S E S HS + Q
Sbjct: 61 LDIDHNKKIDFTEFLLMVFKLAQAYYE--STRKENLPISGHKHRKHSHHDKHEDNKQEEN 118
Query: 121 TEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERIS 180
E + R +++G++G+++ +T G+ ++ +E + ++ S
Sbjct: 119 KE-----NRKRPSSLERRNNRKGNKGRSKSPRETGGK--------RHESSSEKKERKGYS 165
Query: 181 P--QIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETV-----TGSGTQ 233
P + + G+ E + + T + R+ + + E V TG TQ
Sbjct: 166 PTHREEEYGKNHHNSSKKEKNKTENTRLGDNRKRLSERLEEKEDNEEGVYDYENTGRMTQ 225
Query: 234 --TQAG--ATQTVEQDSSHQT------------------GRTSKQT-------------Q 258
Q+G AT QD ++ T G++S Q Q
Sbjct: 226 KWIQSGHIATYYTIQDEAYDTTDSLLEENKIYERSRSSDGKSSSQVNRSRHENTSQVPLQ 285
Query: 259 EATNDQNRGT----ETHGQGRSQTSQAVTG-------GHAQIQAGTHTQTPTQTVEQ--- 304
E+ + RG+ + +G S+ S+ +G G A Q+ ++ P E
Sbjct: 286 ESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGSAWEQSRDGSRHPRSHDEDRAS 345
Query: 305 -----DSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQ-IQAGSHTETV 358
DSS Q+G+ +T S+ GQ + H Q RS + GH Q + H+ T
Sbjct: 346 HGHSADSSRQSGTRHAET--SSRGQTASS--HEQARSSPGERHGSGHQQSADSSRHSATG 401
Query: 359 EQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGR 414
S VS G R +Q G + +G G + Q+ + GR
Sbjct: 402 RGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRGR 457
Score = 77.4 bits (189), Expect = 3e-14
Identities = 92/403 (22%), Positives = 156/403 (38%), Gaps = 33/403 (8%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR-GQN 148
S+++ G GS+ AS++ ++SG +G +H+E SS S + S+ GQ
Sbjct: 555 SDASHGQSGSRS-------ASRQTRNEEQSGDGTRHSGS-RHHEASSQADSSRHSQVGQG 606
Query: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
+ + GS+ D Q S+ ER S + +++ +G R+ +
Sbjct: 607 QSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRHPRSH-HE 665
Query: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGT 268
+R D + ++G T + + QA ++ + S+ + + Q Q A + ++ GT
Sbjct: 666 DRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGERHGSRHQLQSADSSRHSGT 725
Query: 269 ETHGQG----RSQTSQAVTGGHAQIQAGTHTQTPTQTV-------EQDSSHQTGSTSTQT 317
HGQ R + +G A G + TQ+V SHQ +
Sbjct: 726 -GHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
Query: 318 QESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQT 377
+ S + ++ +S++S TG T ++ GSH E + + S G Q
Sbjct: 785 ERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSASQDG---QDTI 841
Query: 378 QTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSSTHPRRCVTEGQGDRQPT 436
+ PGS +R Q S+ E G + T S GR + S G T
Sbjct: 842 RGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQ------SGSRSASRT 895
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
EE D SR + R + + H +S QSE R
Sbjct: 896 TRNEEQSRDGSRHSG-SRHHEASSHADISRHSQAGQGQSEGSR 937
Score = 73.6 bits (179), Expect = 4e-13
Identities = 106/419 (25%), Positives = 158/419 (37%), Gaps = 56/419 (13%)
Query: 95 GACGSQESGSLHSGASQELG--EGQRSGTEVGR----AGKGQHYEGSSHRQ--SQQGSRG 146
G GS S + G S G RS + R +G G + GS H + S+ S G
Sbjct: 2486 GHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGSRHHEASSRADSSG 2545
Query: 147 QNRPGV-QTQGQATGSAWVSSY----DRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
++ G Q++G T W SS+ D Q S+ ER S + ++ +G R+
Sbjct: 2546 HSQVGQGQSEGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2605
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT 261
+ + +R D + Q+G TQT +G + SSH+ R+S + +
Sbjct: 2606 PRSH-QEDRAGHGHSADSSRQSGT----RHTQTSSGG----QAASSHEQARSSAGERHGS 2656
Query: 262 NDQNRGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTVEQDSSH-QT 310
+ Q + G G Q S AV +G A G + TQ+V S+H Q
Sbjct: 2657 HHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV---SAHGQA 2713
Query: 311 GSTSTQTQESTNGQNRGTEIHG---------QGRSQTSQAVTGGHTQIQAGSHTETVEQD 361
GS QES G++ T H +S++S TG T+ + GS E +
Sbjct: 2714 GSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDS 2773
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSST 420
+ S G Q + PGS + Q + E G + T S GR + S
Sbjct: 2774 SRHSASQDG---QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRG 2830
Query: 421 HPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
G T EE D SR + R + + H +S QSE R
Sbjct: 2831 Q------SGSRSASRTTRNEEQSGDGSRHSG-SRHHEASTHADISRHSQAVQGQSEGSR 2882
Score = 72.8 bits (177), Expect = 7e-13
Identities = 110/428 (25%), Positives = 165/428 (38%), Gaps = 64/428 (14%)
Query: 90 SESAEGACGSQESGSLHSGASQELG--EGQRSGTEVGR----AGKGQHYEGSSHRQSQQG 143
S + G GS S + G S G RS + R +G G + GS H ++
Sbjct: 2805 SVDSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTH 2864
Query: 144 SRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK-AGEGKRNQ 202
+ +R QGQ+ GS RQ S SQ+ S G +E +++ +G RN
Sbjct: 2865 A-DISRHSQAVQGQSEGSR---RSRRQGSSVSQDSDS-----EGHSEDSERWSGSASRNH 2915
Query: 203 TTEMRPE-----RQPQTREQDRAHQ--TGETVTGSGT---QTQAGATQTVEQDSSHQTGR 252
+ + R P++ ++DRA + ++ SGT QT +G + SSH+ R
Sbjct: 2916 HGSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGG----QAASSHEQAR 2971
Query: 253 TSKQTQEATNDQNRGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTV 302
+S + ++ Q + G G Q S AV +G A G + TQ+V
Sbjct: 2972 SSAGERHGSHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSV 3031
Query: 303 EQDSSH-QTGSTSTQTQESTNGQNRGTEIHGQG---------RSQTSQAVTGGHTQIQAG 352
S+H Q GS QES G++ T H +S++S TG T+ + G
Sbjct: 3032 ---SAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQG 3088
Query: 353 SHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
S E + + S G Q + PGS + Q + E G + T S
Sbjct: 3089 SRHEQAQDSSRHSASQYG---QDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTS 3145
Query: 413 -GRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
GR + S G T EE D SR +V R + + H +S
Sbjct: 3146 QGRSDASRGQ------SGSRSASRTTRNEEQSGDSSRHSV-SRHHEASTHADISRHSQAV 3198
Query: 472 AAQSEEKR 479
QSE R
Sbjct: 3199 QGQSEGSR 3206
Score = 72.0 bits (175), Expect = 1e-12
Identities = 102/414 (24%), Positives = 160/414 (38%), Gaps = 40/414 (9%)
Query: 96 ACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQ 155
A S++SG+ H+ S G S E R+ G+ + GS H+QS SR P Q
Sbjct: 999 ADSSRQSGTPHAETSS--GGQAASSHEQARSSPGERH-GSRHQQSADSSRHSGIPRRQAS 1055
Query: 156 GQATGSA-WVSSYDRQAESQ--SQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
S W SS + ++S+ S+E + + GQ Q++ + + R R
Sbjct: 1056 SAVRDSGHWGSSGSQASDSEGHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSG 1115
Query: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS-KQTQEATNDQNRGTETH 271
Q H+ E+ G T+T G Q + + + R S Q + T + G+
Sbjct: 1116 SFIYQVSTHEQSESAHGR-TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRG 1174
Query: 272 GQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQNRGTE 329
G+ S Q+V GH+ G+H T D+SH Q+GS S Q + Q+
Sbjct: 1175 GRQGSHHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGS 1230
Query: 330 IHGQGRSQ--TSQAVTGGHTQI----QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
H R S A + H+Q+ +GS T Q S + R ++ GS
Sbjct: 1231 RHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSR-HQGSSVSQDSDSERHSDDSERLSGS 1289
Query: 384 GQRWMQVSNPEA---GETVPG----GQAQTGASTESGRQEWSSTHPRRCVTEGQG----D 432
R S+ E G PG +A G S +S RQ S TH + GQ +
Sbjct: 1290 ASRNHHGSSREQSRDGSRHPGFHQEDRASHGHSADSSRQ--SGTHHTESSSHGQAVSSHE 1347
Query: 433 RQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKRGITAREL 486
+ + GE H + + H+ + Q A + RG + ++
Sbjct: 1348 QARSSPGERHGSRHQQSA------DSSRHSGIGHRQASSAVRDSGHRGSSGSQV 1395
Score = 67.0 bits (162), Expect = 4e-11
Identities = 98/394 (24%), Positives = 155/394 (39%), Gaps = 58/394 (14%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR------GQNRPGV 152
S++SG+ H A G S E R+ G+ + GS H+QS SR GQ V
Sbjct: 2299 SRQSGTHH--AENSSGGQAASSHEQARSSAGERH-GSHHQQSADSSRHSGIGHGQASSAV 2355
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
+ G S +S +E S++ + + GQ Q++ + + R R
Sbjct: 2356 RDSGHRGSSGSQAS---DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 2412
Query: 213 QTREQDRAHQTGETV---TGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269
Q H+ E+ TG+ T + G+ +DSS + TS++ Q+ + + G+
Sbjct: 2413 SFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS--TSQEGQDTIHG-HPGSS 2469
Query: 270 THGQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQNRG 327
+ G+ S Q V GH+ G+H T D+SH +GS S Q + Q+
Sbjct: 2470 SGGRQGSHYEQLVDRSGHS----GSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQSGD 2525
Query: 328 TEIHGQGRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
H R +S+A + GH+Q+ G Q+ +R G + +Q Q
Sbjct: 2526 GSRHSGSRHHEASSRADSSGHSQVGQG-----------QSEGPRTSRNWGSSFSQDSDSQ 2574
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ E E G ++ + + S HPR Q DR G D
Sbjct: 2575 -----GHSEDSERWSGSASRNHHGSAQEQLRDGSRHPR----SHQEDR----AGHGHSAD 2621
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
SR++ G HT SS GQ A+ E+ R
Sbjct: 2622 SSRQS-------GTRHTQTSSG-GQAASSHEQAR 2647
Score = 65.5 bits (158), Expect = 1e-10
Identities = 93/389 (23%), Positives = 149/389 (38%), Gaps = 48/389 (12%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQGQA 158
S++SG+ H+ S G S E R+ G+ + GS H+QS SR P Q
Sbjct: 3271 SRQSGTRHAETSS--GGQAASSHEQARSSPGERH-GSRHQQSADSSRHSGIPRGQASSAV 3327
Query: 159 TGSA-WVSSYDRQAESQ--SQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTR 215
S W SS + ++S+ S+E + + GQ Q++ + + R R
Sbjct: 3328 RDSRHWGSSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFL 3387
Query: 216 EQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS-KQTQEATNDQNRGTETHGQG 274
Q H+ E+ G T+T G Q + + + R S Q + T + G+ G+
Sbjct: 3388 YQVSTHEQSESAHGR-TRTSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQ 3446
Query: 275 RSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQ 333
S Q+V GH+ H+ T +Q S Q+GS S Q + Q+ H
Sbjct: 3447 GSHYEQSVDRSGHS---GSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSW 3503
Query: 334 GRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVS 391
++QA + H+Q G Q+ +R QG + +Q Q + S
Sbjct: 3504 SHHHEASTQADSSRHSQSGQG-----------QSAGPRTSRNQGSSVSQDSDSQGHSEDS 3552
Query: 392 NPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWV-DDHSRET 450
+G + G++ E R G R PT E+ HS E+
Sbjct: 3553 ERWSGS---ASRNHRGSAQEQSR---------------DGSRHPTSHHEDRAGHGHSAES 3594
Query: 451 VILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
Q H + +S+ GQ A+ E+ R
Sbjct: 3595 ----SRQSGTHHAENSSGGQAASSHEQAR 3619
Score = 65.1 bits (157), Expect = 1e-10
Identities = 86/415 (20%), Positives = 148/415 (35%), Gaps = 46/415 (11%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ-SQQGSRGQN 148
S+++ G GS+ + Q + SG+ +H+E SSH S+ GQ
Sbjct: 880 SDASRGQSGSRSASRTTRNEEQSRDGSRHSGS--------RHHEASSHADISRHSQAGQG 931
Query: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
+ + GS+ D + S+ ER S + + +++ G R+ +
Sbjct: 932 QSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSH-HE 990
Query: 209 ERQPQTREQDRAHQTG--ETVTGSGTQTQA-------------GATQTVEQDSSHQTGRT 253
+R D + Q+G T SG Q + G+ DSS +G
Sbjct: 991 DRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIP 1050
Query: 254 SKQTQEATNDQ-------NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+Q A D ++ +++ G +Q+V+ GH Q G H Q+ ++ S
Sbjct: 1051 RRQASSAVRDSGHWGSSGSQASDSEGHSEESDTQSVS-GHG--QDGPHQQSHQESARDWS 1107
Query: 307 SHQTG-STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQT 365
++G S S Q ST+ Q+ HG+ R+ T + H Q + S ++ +
Sbjct: 1108 GGRSGRSGSFIYQVSTHEQSESA--HGRTRTSTGRRQGSHHEQARDSSRHSASQEGQDTI 1165
Query: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRC 425
+H G+R G+ + S T G++ R +S R+
Sbjct: 1166 RAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS--ASRQTRKD 1223
Query: 426 VTEGQGDRQPTVVGEE---WVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEE 477
G G R E W D V G + S QG +Q +
Sbjct: 1224 KQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSG---SRTSRHQGSSVSQDSD 1275
Score = 64.7 bits (156), Expect = 2e-10
Identities = 91/388 (23%), Positives = 148/388 (38%), Gaps = 46/388 (11%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQN---RPGVQTQ 155
S++SG+ H+ S G S E R+ G+ + GS H+QS S R
Sbjct: 1650 SRQSGTRHAETSS--GGQAASSQEQARSSPGERH-GSRHQQSADSSTDSGTGRRQDSSVV 1706
Query: 156 GQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAG-EGKRNQTTEMRPERQPQT 214
G + S +E S+E + + GQ Q++ E R Q+ E R R
Sbjct: 1707 GDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGE-RSGRSGSF 1765
Query: 215 REQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG 274
Q H+ E+ G + G ++ + + + ++ Q + T + G+ G+
Sbjct: 1766 LYQVSTHEQSESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQ 1825
Query: 275 RSQTSQAV-TGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQ 333
S Q+V + GH+ H+ T +Q S Q+GS S Q Q+ H
Sbjct: 1826 GSHYEQSVDSSGHS---GSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSG 1882
Query: 334 GRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVS 391
R +S+A + H+Q+ G Q+ +R QG + +Q Q + S
Sbjct: 1883 SRHHEASSRADSSRHSQVGQG-----------QSSGPRTSRNQGSSVSQDSDSQGHSEDS 1931
Query: 392 NPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETV 451
+G + G++ E R S HP G G D SR++
Sbjct: 1932 ERWSGS---ASRNHLGSAWEQSRD--GSRHP--------GSHHEDRAGHGHSADSSRQS- 1977
Query: 452 ILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
G HT SS++GQ A+ E+ R
Sbjct: 1978 ------GTRHTE-SSSRGQAASSHEQAR 1998
Score = 64.3 bits (155), Expect = 2e-10
Identities = 97/397 (24%), Positives = 151/397 (38%), Gaps = 58/397 (14%)
Query: 96 ACGSQESGSLHSGASQELGEGQRSGT-EVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154
A S++SG+ H+ S GQ + + E R+ G+ + GS H+QS SR
Sbjct: 350 ADSSRQSGTRHAETSSR---GQTASSHEQARSSPGERH-GSGHQQSADSSRHS------A 399
Query: 155 QGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQT 214
G+ S+ VS + S SQ S + T+ G+ Q + R
Sbjct: 400 TGRGQASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVSGHGKAGLRQQSHQESTRG--- 456
Query: 215 REQDRAHQTGETVTGSGTQTQ-------AGATQTVEQDSSHQTGRTSKQTQEATNDQN-- 265
R +R+ ++G ++ T Q G + Q S H+ R S + + Q+
Sbjct: 457 RSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQARDSSRHSASQEGQDTI 516
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTSTQTQESTNGQ 324
RG +G Q S + +G+H T D+SH Q+GS S Q Q
Sbjct: 517 RGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRQTRNEEQ 576
Query: 325 NRGTEIHGQGRSQ--TSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPG 382
+ H R +SQA + H+Q+ G Q+ +R QG + +Q
Sbjct: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQG-----------QSSGPRTSRNQGSSVSQDS 625
Query: 383 SGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEW 442
Q + S +G + G++ E R S HPR DR G
Sbjct: 626 DSQGHSEDSERWSGS---ASRNHHGSAQEQSRD--GSRHPR----SHHEDR----AGHGH 672
Query: 443 VDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEKR 479
D SR++ G HT +S+ GQ A+ E+ R
Sbjct: 673 SADSSRKS-------GTRHTQ-NSSSGQAASSHEQAR 701
Score = 64.3 bits (155), Expect = 2e-10
Identities = 88/363 (24%), Positives = 146/363 (40%), Gaps = 49/363 (13%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
S+++ G GS+ S S + ++ G+G R SG+ +H+E +S S + S+ GQ
Sbjct: 1204 SDASHGQSGSR-SASRQTRKDKQSGDGSRHSGS--------RHHEAASWADSSRHSQVGQ 1254
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
+ + GS+ D + S ER+S + +++ +G R+ +
Sbjct: 1255 EQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRHPGFH-Q 1313
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQA---------------GATQTVEQDSSHQTGR 252
+R D + Q+G T S + QA G+ DSS +G
Sbjct: 1314 EDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHSGI 1373
Query: 253 TSKQTQEATNDQ-NRGTE----THGQGRSQTS--QAVTGGHAQIQAGTHTQTPTQTVEQD 305
+Q A D +RG+ T+ +G S+ S Q+V+ A QAG H Q+ ++
Sbjct: 1374 GHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVS---AHGQAGPHQQSHKESARGQ 1430
Query: 306 SSHQTG-STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
S +G S S Q S++ Q+ T HGQ T H Q + S + QD
Sbjct: 1431 SGESSGRSRSFLYQVSSHEQSEST--HGQTAPSTGGRQGSRHEQAR-NSSRHSASQDGQD 1487
Query: 365 TV------SHGGAREQGQTQTQPGSGQRWMQVSN--PEAGETVPGGQAQTGASTESGRQE 416
T+ S GG + Q+ SG S+ P+ GQ+ +++ R E
Sbjct: 1488 TIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNE 1547
Query: 417 WSS 419
S
Sbjct: 1548 EQS 1550
Score = 64.3 bits (155), Expect = 2e-10
Identities = 88/361 (24%), Positives = 140/361 (38%), Gaps = 62/361 (17%)
Query: 99 SQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR------GQNRPGV 152
S++SG+ H A G S E R+ G+ + GS H+QS SR GQ V
Sbjct: 3595 SRQSGTHH--AENSSGGQAASSHEQARSSAGERH-GSHHQQSADSSRHSGIGHGQASSAV 3651
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
+ G S +S +E S++ + + GQ Q++ + + R R
Sbjct: 3652 RDSGHRGSSGSQAS---DSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSG 3708
Query: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR-----G 267
Q H+ E+ G +AG + Q S H+ R S + + Q+ G
Sbjct: 3709 SFLYQVSTHEQSESAHG-----RAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPG 3763
Query: 268 TETHGQGRSQTSQAVT-GGHAQIQAGTHTQTPTQTVEQDSSH-QTGS------TSTQTQE 319
+ G+ S Q+V GH+ G+H T D+SH Q+GS T + Q
Sbjct: 3764 SRRGGRQGSYHEQSVDRSGHS----GSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQS 3819
Query: 320 STNGQNRGTEIH--------------GQGRSQTSQAVTGGHTQIQAGSHTETVEQD---R 362
++ G+ H GQG S S+ + + S +E +D R
Sbjct: 3820 GDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERR 3879
Query: 363 SQTVS---HGGAREQGQTQTQ-PGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWS 418
S++ S HG +REQ + ++ PGS R + V Q+ +ST +S
Sbjct: 3880 SESASRNHHGSSREQSRDGSRHPGSSHR-------DTASHVQSSPVQSDSSTAKEHGHFS 3932
Query: 419 S 419
S
Sbjct: 3933 S 3933
Score = 63.5 bits (153), Expect = 4e-10
Identities = 86/436 (19%), Positives = 158/436 (36%), Gaps = 54/436 (12%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVG-----------RAGK-GQHYEGSSH 137
SESA G G G S Q + S ++ G R G+ G HYE S
Sbjct: 1775 SESAHGRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQSVD 1834
Query: 138 RQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGE 197
GS + + + G + S RQ ++ Q + S E + +A
Sbjct: 1835 SSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADS 1894
Query: 198 GKRNQTTEMRPERQPQTREQDRA----------HQTGETVTGSGTQTQAGATQTVEQDSS 247
+ +Q + + +R Q + + E +GS ++ G+ +D S
Sbjct: 1895 SRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGS 1954
Query: 248 HQTGRTSKQ-------TQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQ 300
G + + R TE+ +G++ +S A + G+H Q +
Sbjct: 1955 RHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSA 2014
Query: 301 TVEQDSSHQTGSTSTQTQESTN---GQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTET 357
+ S G S+ ++S + ++ ++ G +Q+V+ Q +AG H ++
Sbjct: 2015 DSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVS---AQGKAGPHQQS 2071
Query: 358 VEQDRSQTVSHGGAREQGQTQTQPG-SGQRWMQVSNPEAGETVPGGQAQTGASTESGRQE 416
++ +GQ+ G SG QVS E E+ G A + + +
Sbjct: 2072 HKES-----------ARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYD 2120
Query: 417 WSSTHPRRCVT-EGQ----GDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
+ R + EGQ G P+ G + H ++V G+ H+ +S D
Sbjct: 2121 QAQDSSRHSASQEGQDTIRGHPGPSRGGRQ--GSHQEQSVDRSGHSGSHHSHTTSQGRSD 2178
Query: 472 AAQSEEKRGITARELY 487
A++ + +R+ Y
Sbjct: 2179 ASRGQSGSRSASRKTY 2194
Score = 62.4 bits (150), Expect = 9e-10
Identities = 88/357 (24%), Positives = 141/357 (39%), Gaps = 51/357 (14%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
S+++ G GS+ S S + ++ G+G R SG+ H+E SS S + S GQ
Sbjct: 2177 SDASRGQSGSR-SASRKTYDKEQSGDGSRHSGSH--------HHEASSWADSSRHSLVGQ 2227
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
+ + GS+ D + S+ ER S + +++ +G R+
Sbjct: 2228 GQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRH------ 2281
Query: 208 PERQPQTREQDRA--HQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
P++ +DRA + E+ SGT A + + SSH+ R+S + ++ Q
Sbjct: 2282 ----PRSHHEDRAGHGHSAESSRQSGTH-HAENSSGGQAASSHEQARSSAGERHGSHHQQ 2336
Query: 266 RGTETH--GQGRSQTSQAV--------TGGHAQIQAGTHTQTPTQTVEQDSSH-QTGSTS 314
+ G G Q S AV +G A G + TQ+V S+H Q G
Sbjct: 2337 SADSSRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSV---SAHGQAGPHQ 2393
Query: 315 TQTQESTNGQNRGT---------EIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQT 365
QEST G++ G ++ +S+++ TG T + GSH + +
Sbjct: 2394 QSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHS 2453
Query: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES-GRQEWSSTH 421
S G Q PGS Q S+ E G + T S GR + S H
Sbjct: 2454 TSQEG---QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGH 2507
Score = 61.6 bits (148), Expect = 2e-09
Identities = 94/459 (20%), Positives = 167/459 (36%), Gaps = 70/459 (15%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR-GQN 148
S+++ G GS+ S S + ++ G+G R H+E S+ S + S+ GQ
Sbjct: 3473 SDASRGQSGSR-SASRQTRNDEQSGDGSRHSWS-------HHHEASTQADSSRHSQSGQG 3524
Query: 149 RPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
+ + GS+ D Q S+ ER S + + +++ +G R+ T+
Sbjct: 3525 QSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDGSRHPTSHHED 3584
Query: 209 ER-QPQTREQDRAHQTGETVTGSGTQTQA-------------GATQTVEQDSSHQTGRTS 254
+ E R T SG Q + G+ DSS +G
Sbjct: 3585 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRHSGIGH 3644
Query: 255 KQTQEATNDQ-------NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSS 307
Q A D ++ +++ G +Q+V+ A QAG H Q+ ++ S+
Sbjct: 3645 GQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVS---AHGQAGPHQQSHQESTRGRSA 3701
Query: 308 HQTGSTST--------QTQESTNGQ------NRGTEIHGQGR-------SQTSQAVTGGH 346
++G + + + ES +G+ R H Q R SQ Q GH
Sbjct: 3702 GRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGH 3761
Query: 347 TQIQAGS-----HTETVEQDRSQTVSHGGAREQGQTQTQPG-SGQRWMQVSNPEAGETVP 400
+ G H ++V++ H QG++ G SG R ++
Sbjct: 3762 PGSRRGGRQGSYHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGD 3821
Query: 401 GGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNL 460
G + E+ Q SS H + E G R+ G D E + +
Sbjct: 3822 GSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSDSEA----YPEDSE 3877
Query: 461 HTSVSSAQGQDAAQSEEKR------GITARELYSYLRST 493
S S+++ + E+ R G + R+ S+++S+
Sbjct: 3878 RRSESASRNHHGSSREQSRDGSRHPGSSHRDTASHVQSS 3916
Score = 58.2 bits (139), Expect = 2e-08
Identities = 82/354 (23%), Positives = 142/354 (40%), Gaps = 47/354 (13%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQR-SGTEVGRAGKGQHYEGSSHRQSQQGSR-GQ 147
S+++ G G + S S + ++ G+G R SG+ +H+E S+ S + S+ GQ
Sbjct: 1528 SDASHGQSGPR-SASRQTRNEEQSGDGSRHSGS--------RHHEPSTRAGSSRHSQVGQ 1578
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
+ GS+ D + S+ ER S + +++ G RN + +
Sbjct: 1579 GESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHGSRNPRSH-Q 1637
Query: 208 PERQPQTREQDRAHQTG----ETVTG---SGTQTQA--------GATQTVEQDSSHQTGR 252
+R + + Q+G ET +G + +Q QA G+ DSS +G
Sbjct: 1638 EDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGT 1697
Query: 253 TSKQTQEATNDQ-NRG------TETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQD 305
+Q D NRG +++ G +Q+V+ A QAG H Q+ ++
Sbjct: 1698 GRRQDSSVVGDSGNRGSSGSQASDSEGHSEESDTQSVS---AHGQAGPHQQSHQESTRGQ 1754
Query: 306 SSHQTG-STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
S ++G S S Q ST+ Q+ HG+ T H Q + S + Q+
Sbjct: 1755 SGERSGRSGSFLYQVSTHEQSESA--HGRTGPSTGGRQRSRHEQARDSSR-HSASQEGQD 1811
Query: 365 TV------SHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
T+ S GG + Q+ SG S+ + E + Q+G+ + S
Sbjct: 1812 TIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVS 1865
Score = 57.4 bits (137), Expect = 3e-08
Identities = 114/473 (24%), Positives = 174/473 (36%), Gaps = 112/473 (23%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T S SA+G G H + +E GQ SG GR+G Y+ S+H QS+ + GQ
Sbjct: 2056 TQSVSAQGKAGP------HQQSHKESARGQ-SGESSGRSGSFL-YQVSTHEQSES-THGQ 2106
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQ---------------IQLSGQTEQT 192
+ P +TG S YD QA+ S+ S + Q S Q +
Sbjct: 2107 SAP-------STGGRQGSHYD-QAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSV 2158
Query: 193 QKAG---------------EGKRNQTTEMRPERQPQTREQ--DRAHQTG----------- 224
++G + R Q+ R+ +EQ D + +G
Sbjct: 2159 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWAD 2218
Query: 225 ---ETVTG----SGTQTQAGATQTVEQ---------DSSHQTGRTSK----QTQEATNDQ 264
++ G SG +T +V Q DS ++G S+ QE + D
Sbjct: 2219 SSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDG 2278
Query: 265 NRGTETH-----GQGRSQTSQAVTG-GHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ 318
+R +H G G S S +G HA+ +G + + + + GS Q+
Sbjct: 2279 SRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSA 2338
Query: 319 ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVS-HG--GAREQG 375
+S+ G HGQ S + G + QA E +Q+VS HG G +Q
Sbjct: 2339 DSSRHSGIG---HGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQS 2395
Query: 376 QTQTQPG--------SGQRWMQVSNPEAGETVPGGQAQTGAST--ESGRQEWSSTHPRRC 425
++ G SG QVS E E+ G +TG ST G + R
Sbjct: 2396 HQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG---RTGTSTGGRQGSHHKQARDSSRH 2452
Query: 426 VTEGQGDRQPTVVGEEWVDDHSR-----ETVILRLDQGNLHTSVSSAQGQDAA 473
T +G Q T+ G R E ++ R H S +++QG+ A
Sbjct: 2453 STSQEG--QDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDA 2503
Score = 53.1 bits (126), Expect = 6e-07
Identities = 77/374 (20%), Positives = 135/374 (36%), Gaps = 36/374 (9%)
Query: 94 EGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQ-------------HYEGSSHRQS 140
+ A S+ SG+ H AS + + G+ +A + H + H+QS
Sbjct: 715 QSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHGQAGHHQQS 774
Query: 141 QQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKR 200
Q S ++R G +++ + VS++ + S S ++ EQ +
Sbjct: 775 HQES-ARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQARDNSRHSA 833
Query: 201 NQ----TTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
+Q T P + R+ Q+ + SG+ +Q S Q+G S
Sbjct: 834 SQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASRGQSGSRSAS 893
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS 314
+Q+R H R +S A H+Q G + T + S Q +
Sbjct: 894 RTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQSEGSRTSRRQGSSVSQDSDSE 953
Query: 315 TQTQESTNGQNRGTEIH---GQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSH--- 368
+++S + H Q +S+ H + +AG H + + R H
Sbjct: 954 GHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHEDRAG-HGHSADSSRQSGTPHAET 1012
Query: 369 --GG--AREQGQTQTQPGS--GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHP 422
GG A Q ++ PG G R Q ++ +P QA + A +SG W S+
Sbjct: 1013 SSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPRRQA-SSAVRDSG--HWGSSGS 1069
Query: 423 RRCVTEGQGDRQPT 436
+ +EG + T
Sbjct: 1070 QASDSEGHSEESDT 1083
Score = 50.4 bits (119), Expect = 4e-06
Identities = 82/395 (20%), Positives = 140/395 (35%), Gaps = 70/395 (17%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQ-------------HYEGSS 136
S + A S+ SG H AS + + G +A + H + S
Sbjct: 2980 SHHQQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGS 3039
Query: 137 HRQSQQGSRGQNRPGVQTQGQATGSAW-VSSYDRQAESQSQERISPQIQLSGQTEQTQKA 195
H+QS Q S + R G +T G + + VS++++ S S + + + EQ Q +
Sbjct: 3040 HQQSHQES-ARGRSG-ETSGHSGSFLYQVSTHEQSESSHGWTGPSTRGRQGSRHEQAQDS 3097
Query: 196 GEGKRNQTTEMRPERQP-QTREQDRAHQTGETVTGSG--------TQTQAGATQTVEQDS 246
+Q + P +R + + +V SG T +Q + + Q
Sbjct: 3098 SRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDASRGQSG 3157
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGR-----SQTSQAVTGGHAQIQAGTHTQTPTQT 301
S RT++ +++ + H + S+ SQAV G Q + ++ +
Sbjct: 3158 SRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQG---QSEGSRRSRRQGSS 3214
Query: 302 VEQDSSHQ---------TGSTSTQTQESTNGQNRGTEIH-----------GQGRSQTSQA 341
V QDS + +GS S + S Q+R H G ++ Q+
Sbjct: 3215 VSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAGHGHSADRSRQS 3274
Query: 342 VTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPG 401
T G + EQ RS G+R Q + SG +P
Sbjct: 3275 GTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSG--------------IPR 3320
Query: 402 GQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
GQA +S + W S+ + +EG + T
Sbjct: 3321 GQA---SSAVRDSRHWGSSGSQASDSEGHSEESDT 3352
Score = 43.5 bits (101), Expect = 4e-04
Identities = 40/185 (21%), Positives = 75/185 (40%), Gaps = 22/185 (11%)
Query: 90 SESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNR 149
S+++ G GS+ AS+E ++SG +G H + S+ GQ
Sbjct: 3797 SDASHGQSGSRS-------ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGE 3849
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
+ + GS+ D +A + ER S + +++ +G R+
Sbjct: 3850 SAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRH-------- 3901
Query: 210 RQPQTREQDRAH--QTGETVTGSGTQTQAGATQTVEQDSSHQTG---RTSKQTQEATNDQ 264
P + +D A Q+ + S T + G ++ QDS++ +G R S + + + Q
Sbjct: 3902 --PGSSHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQ 3959
Query: 265 NRGTE 269
+ GTE
Sbjct: 3960 SEGTE 3964
>gi|56606114 trichohyalin-like 1 [Homo sapiens]
Length = 904
Score = 82.4 bits (202), Expect = 9e-16
Identities = 134/571 (23%), Positives = 206/571 (36%), Gaps = 99/571 (17%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
MPQLL+N+ +IE F +YA + N LT ELK+L++ EF D +P V++ L
Sbjct: 1 MPQLLRNVLCVIETFHKYASEDSNGATLTGRELKQLIQGEFGD-FFQPCVLHAVEKNSNL 59
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACF---KTLSESAEGACGSQESGSLHS-GASQELGEG 116
L+ D G + F EF++ +F + C+ K+L S E L G+G
Sbjct: 60 LNIDSNGIISFDEFVLAIFNLLNLCYLDIKSLLSSELRQVTKPEKEKLDDVDVQATTGDG 119
Query: 117 Q----RSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQTQ-------GQATGSAWVS 165
Q S T+ R S + G+ G NR + G+A+
Sbjct: 120 QWTVGTSPTQEKRMLPSGMASSSQLIPEESGAVGNNRVDPWREAKTHNFPGEASEHNDPK 179
Query: 166 SYDRQAESQSQERISPQIQLSGQTEQTQK-----AGEGKRNQTTEMRPERQPQTREQDR- 219
+ + + QSQE ++ IQ + E K AG K + TE + + + ++E D
Sbjct: 180 NKHLEGDEQSQE-VAQDIQTTEDNEGQLKTNKPMAGSKKTSSPTERKGQDKEISQEGDEP 238
Query: 220 ---------AHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQ--NRGT 268
Q GE TQ+ + + ++ Q RT K+ + R
Sbjct: 239 AREQSVSKIRDQFGEQEGNLATQS-SPPKEATQRPCEDQEVRTEKEKHSNIQEPPLQRED 297
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHT-----------------QTPTQTVEQDSSHQTG 311
E Q QA +Q Q T + QTP +T G
Sbjct: 298 EPSSQHADLPEQAAARSPSQTQKSTDSKDVCRMFDTQEPGKDADQTPAKTKNLGEPEDYG 357
Query: 312 STSTQTQE-------------STNG-----------QNRGTEIHGQGRSQTSQAVTGG-- 345
TS +TQE S NG + RG E HG + T
Sbjct: 358 RTS-ETQEKECETKDLPVQYGSRNGSETSDMRDERKERRGPEAHGTAGQKERDRKTRPLV 416
Query: 346 -HTQIQAGSHTETVEQDRSQTVSHGGARE----QGQTQTQPG------SGQRWMQVSNPE 394
TQ Q G + E +S+ G + +G QT P SG+
Sbjct: 417 LETQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPELEGTAVSGEEAEHTKEGT 476
Query: 395 AGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDR------QPTVVGEEWVDDHSR 448
A V A T R+ P + G+ R QP V E+
Sbjct: 477 AEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKTHDQP-VEEEDGYQGEDP 535
Query: 449 ETVILRLDQGNLHT--SVSSAQGQDAAQSEE 477
E+ + D+G+ T S++S +G ++++ E
Sbjct: 536 ESPFTQSDEGSSETPNSLASEEGNSSSETGE 566
Score = 43.1 bits (100), Expect = 6e-04
Identities = 71/358 (19%), Positives = 124/358 (34%), Gaps = 59/358 (16%)
Query: 153 QTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
QT + Y R +E+Q +E + + + + + + + + PE
Sbjct: 342 QTPAKTKNLGEPEDYGRTSETQEKECETKDLPVQYGSRNGSETSDMRDERKERRGPEAHG 401
Query: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQ-------EATNDQN 265
+++R +T V TQTQ G Q ++ S + +TQ + T+ +
Sbjct: 402 TAGQKERDRKTRPLVLE--TQTQDGKYQELQGLSKSKDAEKGSETQYLSSEGGDQTHPEL 459
Query: 266 RGTETHGQGRSQTSQAVT----------------GGHAQIQ---------AGTHTQ---T 297
GT G+ T + G + Q G +T+ T
Sbjct: 460 EGTAVSGEEAEHTKEGTAEAFVNSKNAPAAERTLGARERTQDLAPLEKQSVGENTRVTKT 519
Query: 298 PTQTVEQDSSHQ---TGSTSTQTQE-STNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353
Q VE++ +Q S TQ+ E S+ N G S+T + G +Q Q
Sbjct: 520 HDQPVEEEDGYQGEDPESPFTQSDEGSSETPNSLASEEGNSSSETGELPVQGDSQSQGDQ 579
Query: 354 HTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESG 413
H E+V+ GG TQ Q G++ N VP + + TE
Sbjct: 580 HGESVQ---------GGHNNNPDTQRQGTPGEK-----NRALEAVVPAVRGEDVQLTEDQ 625
Query: 414 RQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
Q H +G G + P E ++E+ ++ +L ++ A +D
Sbjct: 626 EQPARGEHK----NQGPGTKGPGAAVEPNGHPEAQESTAGDENRKSLEIEITGALDED 679
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 64.7 bits (156), Expect = 2e-10
Identities = 79/402 (19%), Positives = 149/402 (37%), Gaps = 35/402 (8%)
Query: 89 LSESAEGACGSQESGSLHSGASQELGEGQRSGT-EVGRAGKGQHYEGSSHRQSQQGSRGQ 147
L++ AE + G +S G +++ EG+ GT E G +G + + + RG+
Sbjct: 630 LTDKAEVSEGKAKS----VGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGE 685
Query: 148 -NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
RPG + A W + E + +E Q + ++ ++ GE + + E
Sbjct: 686 MERPGEGEKELAEKEEWKKRDGEEQEQKERE----QGHQKERNQEMEEGGEEEHGEGEEE 741
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
+R+ + ++ + GE G + + + E+ + G+ K +E DQ
Sbjct: 742 EGDREEEEEKEGEGKEEGEGEEVEGEREK----EEGERKKEERAGKEEKGEEEG--DQGE 795
Query: 267 GTETHGQGRSQTSQ---AVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNG 323
G E +GR + + V GG + G + + E + G E G
Sbjct: 796 GEEEETEGRGEEKEEGGEVEGGEVEEGKGEREEEEEEG-EGEEEEGEGEEEEGEGEEEEG 854
Query: 324 QNRGTE--IHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQ- 380
+ +G E G+G + + G + G E E + + G E+G+ + +
Sbjct: 855 EGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEE 914
Query: 381 ---PGSGQRWMQVSNPEAGETVPGGQAQTG-ASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
G G+ + E E G+ + G E EW EG+G+ +
Sbjct: 915 EEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEE---GEGEGEEEGE 971
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQSEEK 478
GEE + E +G +G++ + EE+
Sbjct: 972 GEGEEGEGEGEEEE-----GEGEGEEEEGEEEGEEEGEGEEE 1008
Score = 63.5 bits (153), Expect = 4e-10
Identities = 76/388 (19%), Positives = 140/388 (36%), Gaps = 76/388 (19%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRG-QNR 149
E EG G G +E E + G E G+G+ EG R+ ++G R + R
Sbjct: 726 EMEEGGEEEHGEGEEEEGDREEEEEKEGEGKE---EGEGEEVEGE--REKEEGERKKEER 780
Query: 150 PGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPE 209
G + +G+ G Q E + +E G+ E+ ++ GE + + E + E
Sbjct: 781 AGKEEKGEEEGD--------QGEGEEEET-------EGRGEEKEEGGEVEGGEVEEGKGE 825
Query: 210 RQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTE 269
R+ + E + GE G G + + + + + G + +E + G E
Sbjct: 826 REEEEEEGE-----GEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEE 880
Query: 270 THGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTE 329
G+G + + G + G + E++ G +E G+ G E
Sbjct: 881 EEGEGEGE-EEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGE-----EEGEEGEGEGEE 934
Query: 330 IHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQ 389
G+G + + G + + G E + + G E+G+ + + G G+
Sbjct: 935 EEGEGEGEDGE----GEGEEEEG------EWEGEEEEGEGEGEEEGEGEGEEGEGE---- 980
Query: 390 VSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDHSRE 449
E GE G+ + E G + EG+G+ + GEE
Sbjct: 981 -GEEEEGE----GEGEEEEGEEEGEE------------EGEGEEEGEGEGEE-------- 1015
Query: 450 TVILRLDQGNLHTSVSSAQGQDAAQSEE 477
++G + V +G+ + EE
Sbjct: 1016 -----EEEGEVEGEVEGEEGEGEGEEEE 1038
Score = 49.3 bits (116), Expect = 8e-06
Identities = 42/195 (21%), Positives = 76/195 (38%), Gaps = 20/195 (10%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRP 150
E EG G +E G + GEG+ G G+G+ EG + +G G+
Sbjct: 942 EDGEGE-GEEEEGEWEGEEEEGEGEGEEEGE-----GEGEEGEGEGEEEEGEGE-GEEEE 994
Query: 151 GVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPER 210
G + +G+ G + + E + +E +++ G+ E + GEG+ + E ER
Sbjct: 995 G-EEEGEEEGEG-----EEEGEGEGEEEEEGEVE--GEVEGEEGEGEGEEEEGEEEGEER 1046
Query: 211 QPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSH-----QTGRTSKQTQEATNDQN 265
+ + ++ E G + G + QD + + K + T +
Sbjct: 1047 EKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGSVKYGKHKTYQKK 1106
Query: 266 RGTETHGQGRSQTSQ 280
T T G G+ Q S+
Sbjct: 1107 SVTNTQGNGKEQRSK 1121
Score = 43.1 bits (100), Expect = 6e-04
Identities = 41/189 (21%), Positives = 75/189 (39%), Gaps = 16/189 (8%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRP 150
E EG +E G G +E EG+ G E G G+G EG +G G+
Sbjct: 896 EEEEGEGEGEEEGE---GEGEE-EEGEGKGEEEGEEGEG---EGEEEEGEGEGEDGEGE- 947
Query: 151 GVQTQGQATG--SAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRP 208
G + +G+ G + + E + +E + G+ E ++ GE + + E
Sbjct: 948 GEEEEGEWEGEEEEGEGEGEEEGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEEGEGEE 1007
Query: 209 ERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGT 268
E + + E++ GE + + G + E++ + K+ + N +NR
Sbjct: 1008 EGEGEGEEEEEGEVEGE------VEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREE 1061
Query: 269 ETHGQGRSQ 277
E +G+ Q
Sbjct: 1062 EEEEEGKYQ 1070
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 63.9 bits (154), Expect = 3e-10
Identities = 73/364 (20%), Positives = 133/364 (36%), Gaps = 32/364 (8%)
Query: 89 LSESAEGACGSQESGSLHSG---ASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSR 145
L E+ A + G H+ A ELGE ++ G + G+ +GS H + QG
Sbjct: 1760 LGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETGG-QGSGHEDNLQGEA 1818
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G Q GQ+ G+ + + + + E+Q + S E + G+ + E
Sbjct: 1819 AAG--GDQDPGQSDGAEGIEAPEAEGEAQPE---------SEGVEAPEAEGDAQ-----E 1862
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
E QP++ + + GE S A V+ +S +++ + +
Sbjct: 1863 AEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESV 1922
Query: 266 RGTETHGQG--RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNG 323
ET G+ S+ ++A A +A TQ ++ +E + + ++ E+
Sbjct: 1923 EALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEV 1982
Query: 324 QNRGTEIHGQGRSQTSQA-VTGGHTQIQAGSHTETVEQD--RSQTVSHGGAREQGQTQTQ 380
+ E G+ + ++ ++Q E D +Q S G ++ + +TQ
Sbjct: 1983 EVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ 2042
Query: 381 PGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRR---CVTEGQGDRQPTV 437
G + EA E Q G E+ HP E +G+ QP
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAE----GEAHPESEDVDAQEAEGEAQPES 2098
Query: 438 VGEE 441
G E
Sbjct: 2099 EGVE 2102
Score = 42.7 bits (99), Expect = 8e-04
Identities = 70/365 (19%), Positives = 139/365 (38%), Gaps = 41/365 (11%)
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+G+ S ++Q+ QTQ + S + S + + E+Q + +++
Sbjct: 1928 EGEDEPESEGAEAQEAEEAAQEAEGQTQPE---SEVIESQEAEEEAQPESEDVEALEVEV 1984
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTRE-QDRAHQTGETV------TGSGTQTQAGATQ 240
+T++ + GE + PE + + +E ++ A + V G Q G TQ
Sbjct: 1985 ETQEAE--GEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQ 2042
Query: 241 TVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQ-TSQAVTGGHAQIQAGTHTQ-TP 298
E D+ ++ E + G +G + S+ V A+ +A ++
Sbjct: 2043 KTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE 2102
Query: 299 TQTVEQDSSHQTGSTSTQTQESTNGQNRGTEI-HGQGRSQ-TSQAVTGGHTQIQAGSHTE 356
E ++ G + +T+ ++ G E +G +Q S+ V + +A +E
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESE 2162
Query: 357 TVE----QDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEA-GETVPGGQAQTGASTE 411
+E ++ +Q G + + + QP S + PEA GE P + E
Sbjct: 2163 GIEAQEAEEEAQPELEGVEAPEAEGEAQPES----EGIEAPEAEGEAQPELEGVEAPEAE 2218
Query: 412 SGRQEWSSTHPRRCVT-EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQ 470
E + P T E +G+ QP GE + +G+ S+ Q +
Sbjct: 2219 ----EEAQPEPEGVETPEAEGEAQPESEGETQGE-----------KKGSPQVSLGDGQSE 2263
Query: 471 DAAQS 475
+A++S
Sbjct: 2264 EASES 2268
Score = 40.0 bits (92), Expect = 0.005
Identities = 54/272 (19%), Positives = 100/272 (36%), Gaps = 45/272 (16%)
Query: 166 SYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGE 225
S +++A S ++ +Q Q E+T++ EG+ Q + A Q E
Sbjct: 1280 SEEQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQ---------------EEAVQLEE 1324
Query: 226 TVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGG 285
T T G Q + V+ + + +T +Q +EA ++ ET G+G + +
Sbjct: 1325 TKTEEGLQEEG-----VQLEETKETEGEGQQEEEAQLEEIE--ETGGEGLQEEGVQLEEV 1377
Query: 286 HAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGG 345
+ G + + ++++ + GS +HGQ S+ S G
Sbjct: 1378 KEGPEGGLQGEALEEGLKEEGLPEEGS-----------------VHGQELSEASSPDGKG 1420
Query: 346 HTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQ 405
Q + E R+ + E + T+P S + ++P A E G Q +
Sbjct: 1421 S---QEDDPVQEEEAGRASASAEPCPAEGTEEPTEPPSH---LSETDPSASERQSGSQLE 1474
Query: 406 TGASTESGRQEWSSTHPRRCVTEGQGDRQPTV 437
G G H + T+G +R +V
Sbjct: 1475 PGLEKPPGATMMGQEHTQAQPTQGAAERSSSV 1506
Score = 37.4 bits (85), Expect = 0.032
Identities = 84/359 (23%), Positives = 123/359 (34%), Gaps = 65/359 (18%)
Query: 95 GACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQT 154
G G ++ G L A E G S G +EGSS + G R Q PG
Sbjct: 511 GLGGPEQGGRLTPRARSEEGASSDSSASTGS------HEGSS----EWGGRPQGCPG--- 557
Query: 155 QGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTE---QTQKAGEGKRNQTTEMRPERQ 211
+ +A S +Q S+ + SP + LS Q + G+G Q T R+
Sbjct: 558 KARAETS-------QQEASEGGDPASPALSLSSLRSDDLQAETQGQG-TEQATGAAVTRE 609
Query: 212 PQ------TREQDRAHQTGETVTGS--GTQTQAGATQTVEQDSSHQTGRTSKQTQEATND 263
P + + + A T T T S G + + SS GR + + +
Sbjct: 610 PLVLGLSCSWDSEGASSTPSTCTSSQQGQRRHRSRASAMSSPSSPGLGRVAPRGHPRHSH 669
Query: 264 QNRGTETHGQGRSQTS----------QAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST 313
+ +TH S + +A G +G+ + T TQ +GS
Sbjct: 670 YRK--DTHSPLDSSVTKQVPRPPERRRACQDGSVPRYSGSSSSTRTQASGNLRPPSSGSL 727
Query: 314 STQTQESTNGQNRGTEIHGQGRSQTS--QAVTGGHTQIQAGSHT---ETVEQDRSQTVSH 368
+Q T+ +H S S A + G AGS T + S + S
Sbjct: 728 PSQDLLGTSSATVTPAVHSDFVSGVSPHNAPSAGWAG-DAGSRTCSPAPIPPHTSDSCSK 786
Query: 369 GGAREQGQ--TQTQPGSGQRWMQVSNPEAGE-------------TVPGGQAQTGASTES 412
GA G+ T S +QV PE G T P +AQ G S E+
Sbjct: 787 SGAASLGEEARDTPQPSSPLVLQVGRPEQGAVGPHRSHCCSQPGTQPAQEAQRGPSPEA 845
Score = 29.6 bits (65), Expect = 6.6
Identities = 41/192 (21%), Positives = 70/192 (36%), Gaps = 15/192 (7%)
Query: 93 AEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGV 152
AEG ES + + ++ + + G E A + E + Q
Sbjct: 2185 AEGEA-QPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEG 2243
Query: 153 QTQGQATGSAWVSSYDRQAESQS-------QERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
+TQG+ GS VS D Q+E S ++R +P G T Q+ G ++
Sbjct: 2244 ETQGEKKGSPQVSLGDGQSEEASESSSPVPEDRPTPPPSPGGDTPH-QRPGSQTGPSSSR 2302
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
++ + H G+T + T T E+ ++ +S QE +
Sbjct: 2303 ASSWGNCWQKDSENDHVLGDTRSPDAKST---GTPHAERKATRMYPESSTSEQE---EAP 2356
Query: 266 RGTETHGQGRSQ 277
G+ T QG S+
Sbjct: 2357 LGSRTPEQGASE 2368
>gi|5174663 S100 calcium binding protein P [Homo sapiens]
Length = 95
Score = 62.8 bits (151), Expect = 7e-10
Identities = 33/87 (37%), Positives = 50/87 (57%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M +L + II+ F RY+ +EG+ LT+GELK L+E+E + D VD++L+
Sbjct: 1 MTELETAMGMIIDVFSRYSGSEGSTQTLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKD 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFK 87
LD + V+F EF+V V + AC K
Sbjct: 61 LDANGDAQVDFSEFIVFVAAITSACHK 87
>gi|5032059 S100 calcium-binding protein A12 [Homo sapiens]
Length = 92
Score = 60.1 bits (144), Expect = 5e-09
Identities = 29/78 (37%), Positives = 50/78 (64%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M +L +++ GI+ F +Y+ +G+ L++GELK+LL +E A+ I D A +DE+ +
Sbjct: 1 MTKLEEHLEGIVNIFHQYSVRKGHFDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQG 60
Query: 61 LDEDHTGTVEFKEFLVLV 78
LD + V+F+EF+ LV
Sbjct: 61 LDANQDEQVDFQEFISLV 78
>gi|239754269 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.5 bits (114), Expect = 1e-05
Identities = 86/356 (24%), Positives = 130/356 (36%), Gaps = 40/356 (11%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV---EQDSSHQTGS-- 312
EAT +ET T+ + TG T ++T T + E +S GS
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 313 --TSTQTQESTNGQNRGTEIH--GQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQT 365
TST+ E+T G+E S+T+ A T G T +GS T T S+T
Sbjct: 1174 TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1233
Query: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGET-VPGGQAQTGASTESGRQEWSST 420
+ A + T GS ++ E T + G + T + T SG S+T
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1289
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|169168665 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/281 (23%), Positives = 91/281 (32%), Gaps = 24/281 (8%)
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G V T G T +A + + S + + + +G TE T + EG T
Sbjct: 980 GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTT-VSTTG-TETTITSTEGSETTTVT 1037
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQ 264
E + TG T T T+ T TV S T ++ + T +
Sbjct: 1038 TAGS------ETTAVYTTGSETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089
Query: 265 NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS--------TQ 316
GT T S+T+ G A T T S T ST+ T
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149
Query: 317 TQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQ--AGSHTETVEQDRSQTVSHGGA 371
E+T G+E G T+ + G T AGS T T S+T + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 372 REQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
+ T GS + E G T AST S
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1250
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/310 (23%), Positives = 111/310 (35%), Gaps = 43/310 (13%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT-QTVEQDSSHQTGSTSTQ 316
EAT +ET T+ + TG T ++T T T+ +++ + + S
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQTVSHGGARE 373
T ST G S+T+ A T G T AGS T T S+T +
Sbjct: 1174 TTTSTEG------------SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGS 1221
Query: 374 QGQTQTQPGS 383
+ T + GS
Sbjct: 1222 ETSTPSSAGS 1231
Score = 37.0 bits (84), Expect = 0.041
Identities = 70/352 (19%), Positives = 116/352 (32%), Gaps = 23/352 (6%)
Query: 19 ARTEGN--CTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLV 76
A TEG+ TA T G + ++ I + + V + E T + E
Sbjct: 926 ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 985
Query: 77 LVFKVAQACFKTLSESAEGA-------CGSQESGSLHSGASQELG--EGQRSGTEVGRAG 127
V+ A +T + S EG+ GS+ + +G + EG + T
Sbjct: 986 ----VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+ + + + G V T G T +A + + S S +
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGAT-QTVEQDS 246
+T G +TE T + ET T S T ++ TV + +
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTT-------SSETTTASTTGSEMTTVFTTVSETT 1154
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+ T + T A + T T G + S A + AG+ T T + + + +
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ T + T T S + I G + S A GS T TV
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|113417486 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 37.4 bits (85), Expect = 0.032
Identities = 78/357 (21%), Positives = 122/357 (34%), Gaps = 52/357 (14%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA-------------TQTVEQDS 246
TT + T T + +GSGT T + A T T +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 247 SHQT--GRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQ 304
S T TS +T A+ + T T+ + G A + ++ T + E
Sbjct: 1121 SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE- 1179
Query: 305 DSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
+T + ST E+T G S+T+ A T +GS T T S+
Sbjct: 1180 --GSETTTASTAGSETTTASTAG--------SETTTAST-------SGSETNTACTTGSE 1222
Query: 365 TVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGET-VPGGQAQTGASTESGRQEWSST 420
T + A + T GS ++ E T + G + T + T SG S+T
Sbjct: 1223 TSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1279
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239740898 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1542
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 758 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 817
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 818 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 870
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 871 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 930
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 931 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 990
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 991 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1041
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1042 TETTITSTEGSETTTV 1057
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 869 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 925
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 926 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 985
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 986 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1045
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1046 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1105
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1106 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1165
Query: 437 VV 438
V
Sbjct: 1166 TV 1167
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 470 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 529
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 530 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 578
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 579 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 638
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 639 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 698
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 699 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 755
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 756 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 806
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 872 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 929
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 930 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 989
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 990 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1039
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1040 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1099
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1100 ADLETTTVSTSGSGTTTASTAGSE 1123
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 375 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 434
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 435 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 492
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 493 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 552
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 553 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 612
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 613 ETTTVSTADSENTTASTADSETTSASTTGSE 643
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGSLH--SGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 98 TVSSAGSGTTTASMAGSESTISTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 157
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 158 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 213
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 214 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 273
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 274 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 333
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 334 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 385
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 386 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 435
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 436 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 463
Score = 46.6 bits (109), Expect = 5e-05
Identities = 53/212 (25%), Positives = 80/212 (37%), Gaps = 13/212 (6%)
Query: 220 AHQTGETVTGSGTQT--QAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQ 277
+ T + GSGT T AG+ T+ S +T S E T G+ET +
Sbjct: 94 SENTTVSSAGSGTTTASMAGSESTISTAGS-ETTTVSITGTETTMVSAMGSETTTNSTTS 152
Query: 278 TSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQ 337
+ VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 153 SETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSET 205
Query: 338 TSQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEA 395
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 206 ITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSET 265
Query: 396 GETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 266 TVSTAGSET-TAASTEDSETNTAFTEDSKTTT 296
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 867 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 922
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 923 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 969
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 970 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1029
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1030 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1089
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1090 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1144
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1145 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1204
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1205 TTASTA------GSETTTASTAGSETTTAS 1228
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 651 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 710
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 711 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 770
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 771 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 830
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 831 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 889
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 890 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 933
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/281 (23%), Positives = 91/281 (32%), Gaps = 24/281 (8%)
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G V T G T +A + + S + + + +G TE T + EG T
Sbjct: 1001 GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTT-VSTTG-TETTITSTEGSETTTVT 1058
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQ 264
E + TG T T T+ T TV S T ++ + T +
Sbjct: 1059 TAGS------ETTAVYTTGSETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1110
Query: 265 NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS--------TQ 316
GT T S+T+ G A T T S T ST+ T
Sbjct: 1111 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1170
Query: 317 TQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQ--AGSHTETVEQDRSQTVSHGGA 371
E+T G+E G T+ + G T AGS T T S+T + +
Sbjct: 1171 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1230
Query: 372 REQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
+ T GS + E G T AST S
Sbjct: 1231 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1271
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/310 (23%), Positives = 111/310 (35%), Gaps = 43/310 (13%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 973 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1024
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1025 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1082
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1083 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1141
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT-QTVEQDSSHQTGSTSTQ 316
EAT +ET T+ + TG T ++T T T+ +++ + + S
Sbjct: 1142 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1194
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQTVSHGGARE 373
T ST G S+T+ A T G T AGS T T S+T +
Sbjct: 1195 TTTSTEG------------SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGS 1242
Query: 374 QGQTQTQPGS 383
+ T + GS
Sbjct: 1243 ETSTPSSAGS 1252
Score = 37.4 bits (85), Expect = 0.032
Identities = 56/247 (22%), Positives = 84/247 (34%), Gaps = 12/247 (4%)
Query: 238 ATQTVEQDSSHQTGRT-SKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQ--AGTH 294
AT T DS T + S +T A + T G T+ + AG+
Sbjct: 6 ATTTSTADSKVITASSMSSETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSE 65
Query: 295 TQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQ-AGS 353
T TP+ T Q + + T + +N T + G T+ ++ G + I AGS
Sbjct: 66 TTTPSPTGSQTTIVSISGSEITTTSTAGSEN--TTVSSAGSGTTTASMAGSESTISTAGS 123
Query: 354 HTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESG 413
T TV ++T + T + S + E G T A T
Sbjct: 124 ETTTVSITGTETTMVSAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADS 183
Query: 414 RQEWSST---HPRRCVTEGQGDRQPTVVGEE--WVDDHSRETVILRLDQGNLHTSVSSAQ 468
+ST T G P+ G E V ET + G+ T+ S+A
Sbjct: 184 ETTAASTTGSEMTTVFTAGSETITPSTAGSETTTVSTAGSETTTVS-TTGSETTTASTAH 242
Query: 469 GQDAAQS 475
+ A S
Sbjct: 243 SETTAAS 249
Score = 37.0 bits (84), Expect = 0.041
Identities = 70/352 (19%), Positives = 116/352 (32%), Gaps = 23/352 (6%)
Query: 19 ARTEGN--CTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLV 76
A TEG+ TA T G + ++ I + + V + E T + E
Sbjct: 947 ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 1006
Query: 77 LVFKVAQACFKTLSESAEGA-------CGSQESGSLHSGASQELG--EGQRSGTEVGRAG 127
V+ A +T + S EG+ GS+ + +G + EG + T
Sbjct: 1007 ----VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1062
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+ + + + G V T G T +A + + S S +
Sbjct: 1063 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1122
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGAT-QTVEQDS 246
+T G +TE T + ET T S T ++ TV + +
Sbjct: 1123 ETTTVYITGSKTTTASTEGSEATTVSTT-------SSETTTASTTGSEMTTVFTTVSETT 1175
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+ T + T A + T T G + S A + AG+ T T + + + +
Sbjct: 1176 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN 1235
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ T + T T S + I G + S A GS T TV
Sbjct: 1236 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1287
>gi|239740827 PREDICTED: hypothetical protein XP_002344067 [Homo
sapiens]
Length = 1521
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 49.7 bits (117), Expect = 6e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 43.9 bits (102), Expect = 3e-04
Identities = 59/284 (20%), Positives = 98/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTITSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/281 (23%), Positives = 91/281 (32%), Gaps = 24/281 (8%)
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G V T G T +A + + S + + + +G TE T + EG T
Sbjct: 980 GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTT-VSTTG-TETTITSTEGSETTTVT 1037
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQ 264
E + TG T T T+ T TV S T ++ + T +
Sbjct: 1038 TAGS------ETTAVYTTGSETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089
Query: 265 NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS--------TQ 316
GT T S+T+ G A T T S T ST+ T
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149
Query: 317 TQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQ--AGSHTETVEQDRSQTVSHGGA 371
E+T G+E G T+ + G T AGS T T S+T + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 372 REQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
+ T GS + E G T AST S
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1250
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/310 (23%), Positives = 111/310 (35%), Gaps = 43/310 (13%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT-QTVEQDSSHQTGSTSTQ 316
EAT +ET T+ + TG T ++T T T+ +++ + + S
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQTVSHGGARE 373
T ST G S+T+ A T G T AGS T T S+T +
Sbjct: 1174 TTTSTEG------------SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGS 1221
Query: 374 QGQTQTQPGS 383
+ T + GS
Sbjct: 1222 ETSTPSSAGS 1231
Score = 37.0 bits (84), Expect = 0.041
Identities = 70/352 (19%), Positives = 116/352 (32%), Gaps = 23/352 (6%)
Query: 19 ARTEGN--CTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLV 76
A TEG+ TA T G + ++ I + + V + E T + E
Sbjct: 926 ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 985
Query: 77 LVFKVAQACFKTLSESAEGA-------CGSQESGSLHSGASQELG--EGQRSGTEVGRAG 127
V+ A +T + S EG+ GS+ + +G + EG + T
Sbjct: 986 ----VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+ + + + G V T G T +A + + S S +
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGAT-QTVEQDS 246
+T G +TE T + ET T S T ++ TV + +
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTT-------SSETTTASTTGSEMTTVFTTVSETT 1154
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+ T + T A + T T G + S A + AG+ T T + + + +
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ T + T T S + I G + S A GS T TV
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239740777 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1612
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/281 (23%), Positives = 91/281 (32%), Gaps = 24/281 (8%)
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G V T G T +A + + S + + + +G TE T + EG T
Sbjct: 980 GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTT-VSTTG-TETTITSTEGSETTTVT 1037
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQ 264
E + TG T T T+ T TV S T ++ + T +
Sbjct: 1038 TAGS------ETTAVYTTGSETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089
Query: 265 NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS--------TQ 316
GT T S+T+ G A T T S T ST+ T
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149
Query: 317 TQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQ--AGSHTETVEQDRSQTVSHGGA 371
E+T G+E G T+ + G T AGS T T S+T + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 372 REQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
+ T GS + E G T AST S
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1250
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/310 (23%), Positives = 111/310 (35%), Gaps = 43/310 (13%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT-QTVEQDSSHQTGSTSTQ 316
EAT +ET T+ + TG T ++T T T+ +++ + + S
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQTVSHGGARE 373
T ST G S+T+ A T G T AGS T T S+T +
Sbjct: 1174 TTTSTEG------------SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGS 1221
Query: 374 QGQTQTQPGS 383
+ T + GS
Sbjct: 1222 ETSTPSSAGS 1231
Score = 37.0 bits (84), Expect = 0.041
Identities = 70/352 (19%), Positives = 116/352 (32%), Gaps = 23/352 (6%)
Query: 19 ARTEGN--CTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLV 76
A TEG+ TA T G + ++ I + + V + E T + E
Sbjct: 926 ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 985
Query: 77 LVFKVAQACFKTLSESAEGA-------CGSQESGSLHSGASQELG--EGQRSGTEVGRAG 127
V+ A +T + S EG+ GS+ + +G + EG + T
Sbjct: 986 ----VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+ + + + G V T G T +A + + S S +
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGAT-QTVEQDS 246
+T G +TE T + ET T S T ++ TV + +
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTT-------SSETTTASTTGSEMTTVFTTVSETT 1154
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+ T + T A + T T G + S A + AG+ T T + + + +
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ T + T T S + I G + S A GS T TV
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239740724 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1704
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 43.9 bits (102), Expect = 3e-04
Identities = 65/281 (23%), Positives = 91/281 (32%), Gaps = 24/281 (8%)
Query: 146 GQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTE 205
G V T G T +A + + S + + + +G TE T + EG T
Sbjct: 980 GSETTTVSTAGSETTTASIEGSETTTVSSTGSETTT-VSTTG-TETTITSTEGSETTTVT 1037
Query: 206 MRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEAT-NDQ 264
E + TG T T T+ T TV S T ++ + T +
Sbjct: 1038 TAGS------ETTAVYTTGSETTT--TSTEGSETTTVSTTGSETTTASTADLETTTVSTS 1089
Query: 265 NRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS--------TQ 316
GT T S+T+ G A T T S T ST+ T
Sbjct: 1090 GSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMTTVFTT 1149
Query: 317 TQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQ--AGSHTETVEQDRSQTVSHGGA 371
E+T G+E G T+ + G T AGS T T S+T + +
Sbjct: 1150 VSETTTVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTS 1209
Query: 372 REQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTES 412
+ T GS + E G T AST S
Sbjct: 1210 GSETNTACTTGSETSTPSSAGSETNTAFIIGSETTIASTAS 1250
Score = 42.4 bits (98), Expect = 0.001
Identities = 72/310 (23%), Positives = 111/310 (35%), Gaps = 43/310 (13%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPT-QTVEQDSSHQTGSTSTQ 316
EAT +ET T+ + TG T ++T T T+ +++ + + S
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQTVSHGGARE 373
T ST G S+T+ A T G T AGS T T S+T +
Sbjct: 1174 TTTSTEG------------SETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGS 1221
Query: 374 QGQTQTQPGS 383
+ T + GS
Sbjct: 1222 ETSTPSSAGS 1231
Score = 37.0 bits (84), Expect = 0.041
Identities = 70/352 (19%), Positives = 116/352 (32%), Gaps = 23/352 (6%)
Query: 19 ARTEGN--CTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEFLV 76
A TEG+ TA T G + ++ I + + V + E T + E
Sbjct: 926 ASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTMGSETTTASTAGSETTT 985
Query: 77 LVFKVAQACFKTLSESAEGA-------CGSQESGSLHSGASQELG--EGQRSGTEVGRAG 127
V+ A +T + S EG+ GS+ + +G + EG + T
Sbjct: 986 ----VSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGS 1041
Query: 128 KGQHYEGSSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSG 187
+ + + + G V T G T +A + + S S +
Sbjct: 1042 ETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGS 1101
Query: 188 QTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGAT-QTVEQDS 246
+T G +TE T + ET T S T ++ TV + +
Sbjct: 1102 ETTTVYITGSKTTTASTEGSEATTVSTT-------SSETTTASTTGSEMTTVFTTVSETT 1154
Query: 247 SHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDS 306
+ T + T A + T T G + S A + AG+ T T + + + +
Sbjct: 1155 TVSTIGSEATTSSAAGSEATTTSTEGSETTTASTAGSETTTASTAGSETTTASTSGSETN 1214
Query: 307 SHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
+ T + T T S + I G + S A GS T TV
Sbjct: 1215 TACTTGSETSTPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTV 1266
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239740674 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.5 bits (114), Expect = 1e-05
Identities = 86/356 (24%), Positives = 130/356 (36%), Gaps = 40/356 (11%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV---EQDSSHQTGS-- 312
EAT +ET T+ + TG T ++T T + E +S GS
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 313 --TSTQTQESTNGQNRGTEIH--GQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQT 365
TST+ E+T G+E S+T+ A T G T +GS T T S+T
Sbjct: 1174 TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1233
Query: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGET-VPGGQAQTGASTESGRQEWSST 420
+ A + T GS ++ E T + G + T + T SG S+T
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1289
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239740645 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1531
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.5 bits (114), Expect = 1e-05
Identities = 86/356 (24%), Positives = 130/356 (36%), Gaps = 40/356 (11%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQT 257
TT + T T + +GSGT T AG+ T + +T S +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV---EQDSSHQTGS-- 312
EAT +ET T+ + TG T ++T T + E +S GS
Sbjct: 1121 SEATTVSTTSSET-------TTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEA 1173
Query: 313 --TSTQTQESTNGQNRGTEIH--GQGRSQTSQAVTGGH---TQIQAGSHTETVEQDRSQT 365
TST+ E+T G+E S+T+ A T G T +GS T T S+T
Sbjct: 1174 TTTSTEGSETTTASTAGSETTTASTAGSETTTASTAGSETTTASTSGSETNTACTTGSET 1233
Query: 366 VSHGGAREQGQTQTQPGSGQRWMQVSNPEAGET-VPGGQAQTGASTESGRQEWSST 420
+ A + T GS ++ E T + G + T + T SG S+T
Sbjct: 1234 STPSSAGSETNTAFIIGSETTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1289
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|239513940 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1521
Score = 57.4 bits (137), Expect = 3e-08
Identities = 81/316 (25%), Positives = 114/316 (36%), Gaps = 38/316 (12%)
Query: 144 SRGQNRPGVQTQGQATGSAWVS-SYDRQAESQSQERISPQIQLSGQT------EQTQKAG 196
+ G T+G T SA + S A + S E I S T +T K
Sbjct: 737 TEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVS 796
Query: 197 EGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQ 256
TT E T A +T TV+ +G++T +T S T TS +
Sbjct: 797 TASSKMTTVFT-ENSETTIASTTASET-TTVSTAGSETIPASTA-----GSETTTTTSTE 849
Query: 257 TQEATNDQNRGTETHGQGR--SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST- 313
E T G+ET S+T+ A T G A T T T + S T ST
Sbjct: 850 GSETTTASTEGSETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTE 909
Query: 314 -------STQTQESTNGQNRGTEI---HGQGRSQTSQAVTGGHTQIQA--GSHTETVEQD 361
ST E+T G+E +G T+ + TG T + GS T TV
Sbjct: 910 GSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTTM 969
Query: 362 RSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTH 421
S+T + A + T + GS ++ G + T +ST S S+T
Sbjct: 970 GSETTTASTAGSETTTVSTAGS---------ETTTASIEGSETTTVSSTGSETTTVSTTG 1020
Query: 422 PRRCVTEGQGDRQPTV 437
+T +G TV
Sbjct: 1021 TETTITSTEGSETTTV 1036
Score = 56.6 bits (135), Expect = 5e-08
Identities = 67/302 (22%), Positives = 105/302 (34%), Gaps = 20/302 (6%)
Query: 154 TQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQPQ 213
T+G T +A + S + + +T T + EG TT +
Sbjct: 848 TEGSETTTASTEGSETTTASTESSETTTATTIGSET--TTASTEGSETTTTSTEGS-ETT 904
Query: 214 TREQDRAHQTGETVTGSGT---QTQAGATQTVEQDSSHQT--GRTSKQTQEATNDQNRGT 268
T + + T + TGS T T+ T T + S T T +T + + + T
Sbjct: 905 TASTEGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETT 964
Query: 269 ETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ-------EST 321
G T+ + G + ++T T ++E + ST ++T E+T
Sbjct: 965 TVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSSTGSETTTVSTTGTETT 1024
Query: 322 NGQNRGTE---IHGQGRSQTSQAVTGGHTQIQA--GSHTETVEQDRSQTVSHGGAREQGQ 376
G+E + G T+ TG T + GS T TV S+T + A +
Sbjct: 1025 ITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTASTADLETT 1084
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GSG + E G T ASTE ST T + T
Sbjct: 1085 TVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEATTVSTTSSETTTASTTGSEMT 1144
Query: 437 VV 438
V
Sbjct: 1145 TV 1146
Score = 50.4 bits (119), Expect = 4e-06
Identities = 63/351 (17%), Positives = 123/351 (35%), Gaps = 24/351 (6%)
Query: 135 SSHRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQK 194
S + + G V T G T +A+ + + S + + + T
Sbjct: 449 SDSETTTASTEGSETTTVTTAGSETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTAST 508
Query: 195 AGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTS 254
G ++TT + T + TV+ +G++T +T +E T TS
Sbjct: 509 EG----SETTAVSATGSEMTTVSTEGSEN-TTVSTTGSETTTVSTTGLE------TTTTS 557
Query: 255 KQTQEATNDQNRGTET---HGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG 311
+ E T G ET +G T+ + G + ++ T + +
Sbjct: 558 TEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGSETTTVSTADSENTTASTADSETTSAS 617
Query: 312 STSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTE----TVEQDRSQTVS 367
+T ++T ++ + T +G T+ + T T + + + +E + E + TVS
Sbjct: 618 TTGSETTTASTTSSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVS 677
Query: 368 HGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSS---THPRR 424
G+ T+ GSG + ++ E + G T STE +S +
Sbjct: 678 ATGSETTVSTE---GSGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTT 734
Query: 425 CVTEGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
TEG + G E + + + T+++S G + +
Sbjct: 735 ASTEGSETTTASTEGSETTSASTTGSETTTASTTSSETTMASIMGSETTMA 785
Score = 49.3 bits (116), Expect = 8e-06
Identities = 59/264 (22%), Positives = 90/264 (34%), Gaps = 23/264 (8%)
Query: 189 TEQTQKAGEGKRNQTTEMRPERQPQTR------EQDRAHQTGETVTGSGTQTQAGATQTV 242
+E T + EG ++TT E T E A G T + T+ T +
Sbjct: 851 SETTTASTEG--SETTTASTESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTAST 908
Query: 243 EQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTV 302
E T +T A+ + + T +G T+ + TG + ++T T T
Sbjct: 909 EGSEITTVSTTGSETTTASTEGSETTTASTEGSELTTVSTTGSETITVSAEGSETTTVTT 968
Query: 303 EQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQI--QAGSHTETVEQ 360
+T + ST E+T G+E T+ ++ G T GS T TV
Sbjct: 969 ---MGSETTTASTAGSETTTVSTAGSE-------TTTASIEGSETTTVSSTGSETTTVST 1018
Query: 361 DRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSST 420
++T + T T GS + + E T G T ST +ST
Sbjct: 1019 TGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVSTTGSETTTAST 1078
Query: 421 ---HPRRCVTEGQGDRQPTVVGEE 441
T G G + G E
Sbjct: 1079 ADLETTTVSTSGSGTTTASTAGSE 1102
Score = 48.1 bits (113), Expect = 2e-05
Identities = 63/271 (23%), Positives = 95/271 (35%), Gaps = 24/271 (8%)
Query: 223 TGETVTGSGTQTQA--GATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQG--RSQT 278
T ++ GS T T + G+ T +T S + EAT G+ET S+T
Sbjct: 354 TTASIMGSETSTDSTTGSETTTASTEGSETTTASTEGSEATTVSTTGSETTTVSITDSET 413
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIH--GQGRS 336
+ T G +++ A + T T T + S T ST E+T G+E S
Sbjct: 414 TTTCTEG-SEMTAVSTTVFETTTASTEGSEIT-IASTSDSETTTASTEGSETTTVTTAGS 471
Query: 337 QTSQAVTGGH-------------TQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGS 383
+T A T G T GS T T + S+T + + T + GS
Sbjct: 472 ETKTAYTTGSETTTASNTGLETTTVFTIGSDTTTASTEGSETTAVSATGSEMTTVSTEGS 531
Query: 384 GQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCV---TEGQGDRQPTVVGE 440
+ + E G T STE ST TEG G + G
Sbjct: 532 ENTTVSTTGSETTTVSTTGLETTTTSTEGSEMTTVSTTGAETTTDSTEGSGTTAASTAGS 591
Query: 441 EWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + ++ + T+ +S G +
Sbjct: 592 ETTTVSTADSENTTASTADSETTSASTTGSE 622
Score = 47.8 bits (112), Expect = 2e-05
Identities = 87/395 (22%), Positives = 135/395 (34%), Gaps = 40/395 (10%)
Query: 88 TLSESAEGACGSQESGS--LHSGASQELGEGQRSGTEVGR-AGKGQHYEGSSHRQSQQ-- 142
T+S + G + +GS S A E +GTE + G +S S+
Sbjct: 77 TVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSSETTV 136
Query: 143 -GSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ G V T G T +A+ + + A S + ++ +T AG +
Sbjct: 137 TSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTVFTAGSETITPSTAG----S 192
Query: 202 QTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA----TQTVEQDSSHQTGRTSKQT 257
+TT + T +T T T A T V S T T+
Sbjct: 193 ETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETTVSTAGSE 252
Query: 258 QEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGST-STQ 316
A + ++ T T S+T+ A T G A T PT S ST +
Sbjct: 253 TTAASTEDSETNTAFTEDSKTTTASTTGFETTAASTTGSEPTMASTMGSETTMASTIGPE 312
Query: 317 TQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQ 376
T + + + T + G S+T +A T GS T TV S+T + +
Sbjct: 313 TTKVSTASSEVTTVFAAG-SETIRAST-------VGSETTTVSTTGSETTTASIMGSETS 364
Query: 377 TQTQPGSGQRWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPT 436
T + GS ++ E ET T ASTE ST T D + T
Sbjct: 365 TDSTTGSETT---TASTEGSET-------TTASTEGSEATTVSTTGSETTTVSITDSETT 414
Query: 437 VVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E + + T + T+ +S +G +
Sbjct: 415 TTCTEGSEMTAVSTTV-------FETTTASTEGSE 442
Score = 46.6 bits (109), Expect = 5e-05
Identities = 51/211 (24%), Positives = 80/211 (37%), Gaps = 11/211 (5%)
Query: 220 AHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHGQGRSQT 278
+ T + GSGT T + A ++T + +T S E T G+ET + +
Sbjct: 73 SENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMVSAMGSETTTNSTTSS 132
Query: 279 SQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQT 338
VT AG+ T T + + ++ T + T T ST G T + G
Sbjct: 133 ETTVTS-----TAGSETTTVSTVGSETTTAYTADSET-TAASTTGSEM-TTVFTAGSETI 185
Query: 339 SQAVTGGHTQI--QAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAG 396
+ + G T AGS T TV S+T + A + + GS + + E
Sbjct: 186 TPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKVSTAGSETT 245
Query: 397 ETVPGGQAQTGASTESGRQEWSSTHPRRCVT 427
+ G + T ASTE + T + T
Sbjct: 246 VSTAGSET-TAASTEDSETNTAFTEDSKTTT 275
Score = 46.6 bits (109), Expect = 5e-05
Identities = 85/390 (21%), Positives = 132/390 (33%), Gaps = 30/390 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQ 147
T +E +E S E GS + AS E E + T +G EGS + + G
Sbjct: 846 TSTEGSETTTASTE-GSETTTASTESSE-TTTATTIGSETTTASTEGSE--TTTTSTEGS 901
Query: 148 NRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMR 207
T+G + VS+ + + S E +E T + EG TT
Sbjct: 902 ETTTASTEGSEITT--VSTTGSETTTASTEG----------SETTTASTEGSE-LTTVST 948
Query: 208 PERQPQTREQDRAHQTGETVTGSGTQTQ--AGATQTVEQDSSHQTGRTSKQTQEATNDQN 265
+ T + + T T GS T T AG+ T + +T S + E T +
Sbjct: 949 TGSETITVSAEGSETTTVTTMGSETTTASTAGSETTTVSTAGSETTTASIEGSETTTVSS 1008
Query: 266 RGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQN 325
G+ET + T +T T T + +T +TST+ E+T
Sbjct: 1009 TGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGSETTTVST 1068
Query: 326 RGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQ 385
G+E + S A T +GS T T S+T + + T + GS
Sbjct: 1069 TGSET-----TTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEGSEA 1123
Query: 386 RWMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDD 445
+ ++ E G T T ST T + T E +
Sbjct: 1124 TTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTEGSET 1183
Query: 446 HSRETVILRLDQGNLHTSVSSAQGQDAAQS 475
+ T G+ T+ S+A + S
Sbjct: 1184 TTASTA------GSETTTASTAGSETTTAS 1207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 60/284 (21%), Positives = 99/284 (34%), Gaps = 36/284 (12%)
Query: 223 TGETVTGS--GTQTQAGATQTVEQDSSHQTGR----TSKQTQEATNDQNRGTET--HGQG 274
+ ET T S G++T +T E TG TS + E T G+ET +G
Sbjct: 630 SSETTTASTEGSETTTVSTTDSETTMVSTTGSERTITSTEGSETTTVSATGSETTVSTEG 689
Query: 275 RSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHGQG 334
T+ ++TG + T ++T T + E T ++T ++ + T +G
Sbjct: 690 SGTTTVSITGSETTKVSTTGSETTTTSTEGSEITTASITGSETTTASTEGSETTTASTEG 749
Query: 335 RSQTSQAVTGGHTQIQAGSHTETV-------EQDRSQTVSHGGAR-------------EQ 374
TS + TG T + + +ET E + T+ + E
Sbjct: 750 SETTSASTTGSETTTASTTSSETTMASIMGSETTMASTIGSETTKVSTASSKMTTVFTEN 809
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVP----GGQAQTGASTESGRQEWSSTHPRRCV---T 427
+T + VS ET+P G + T STE +ST T
Sbjct: 810 SETTIASTTASETTTVST-AGSETIPASTAGSETTTTTSTEGSETTTASTEGSETTTAST 868
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQD 471
E T +G E + + T+ +S +G +
Sbjct: 869 ESSETTTATTIGSETTTASTEGSETTTTSTEGSETTTASTEGSE 912
Score = 44.3 bits (103), Expect = 3e-04
Identities = 61/242 (25%), Positives = 88/242 (36%), Gaps = 19/242 (7%)
Query: 185 LSGQTEQTQKAGEGKRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQA--GATQTV 242
+S +T AG N TT + T + T + GS T T + G+ T+
Sbjct: 1 MSSETTVAPAAGS---NTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTI 57
Query: 243 EQDSSHQTGRTSKQTQEAT--NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQT--- 297
S + TS E T + GT T S+T+ + G + T T+T
Sbjct: 58 VSISGSEITTTSTAGSENTTVSSAGSGTTTASMAGSETTVSTAGSETTTVSITGTETTMV 117
Query: 298 ----PTQTVEQDSSHQTGSTSTQTQESTNGQNRGTEIHG--QGRSQTSQAVTGGH---TQ 348
T +S +T TST E+T G+E S+T+ A T G T
Sbjct: 118 SAMGSETTTNSTTSSETTVTSTAGSETTTVSTVGSETTTAYTADSETTAASTTGSEMTTV 177
Query: 349 IQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGETVPGGQAQTGA 408
AGS T T S+T + A + T + GS ++ E G T
Sbjct: 178 FTAGSETITPSTAGSETTTVSTAGSETTTVSTTGSETTTASTAHSETTAASTMGSETTKV 237
Query: 409 ST 410
ST
Sbjct: 238 ST 239
Score = 37.4 bits (85), Expect = 0.032
Identities = 78/357 (21%), Positives = 122/357 (34%), Gaps = 52/357 (14%)
Query: 87 KTLSESAEGA-------CGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQ 139
+T++ SAEG+ GS+ + + S A E +G+E A EGS
Sbjct: 952 ETITVSAEGSETTTVTTMGSETTTA--STAGSETTTVSTAGSETTTAS----IEGSE--T 1003
Query: 140 SQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGK 199
+ S G V T G T + + + + +T T G
Sbjct: 1004 TTVSSTGSETTTVSTTGTETTITSTEGSETTTVTTAGSETTAVYTTGSETTTTSTEGS-- 1061
Query: 200 RNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGA-------------TQTVEQDS 246
TT + T T + +GSGT T + A T T +
Sbjct: 1062 -ETTTVSTTGSETTTASTADLETTTVSTSGSGTTTASTAGSETTTVYITGSKTTTASTEG 1120
Query: 247 SHQT--GRTSKQTQEATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQ 304
S T TS +T A+ + T T+ + G A + ++ T + E
Sbjct: 1121 SEATTVSTTSSETTTASTTGSEMTTVFTTVSETTTVSTIGSEATTSSAAGSEATTTSTE- 1179
Query: 305 DSSHQTGSTSTQTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQ 364
+T + ST E+T G S+T+ A T +GS T T S+
Sbjct: 1180 --GSETTTASTAGSETTTASTAG--------SETTTAST-------SGSETNTACTTGSE 1222
Query: 365 TVSHGGAREQGQTQTQPGSGQRWMQVSNPEAGET-VPGGQAQTGASTESGRQEWSST 420
T + A + T GS ++ E T + G + T + T SG S+T
Sbjct: 1223 TSTPSSAGSETNTAFIIGSESTIASTASLEPTATSLTGSETTTVSITASGATAASTT 1279
Score = 32.7 bits (73), Expect = 0.78
Identities = 39/148 (26%), Positives = 52/148 (35%), Gaps = 14/148 (9%)
Query: 276 SQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTS---TQTQESTNGQNRGTEIHG 332
S+T+ A G A T T + + S T ST+ T T T Q I G
Sbjct: 3 SETTVAPAAGSNTTTASTTGSETTTILIKASETTTASTAGSETTTPSPTGSQTTIVSISG 62
Query: 333 QGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSN 392
+ TS A + T AGS T T S+T T + GS + ++
Sbjct: 63 SEITTTSTAGSENTTVSSAGSGTTTASMAGSET-----------TVSTAGSETTTVSITG 111
Query: 393 PEAGETVPGGQAQTGASTESGRQEWSST 420
E G T ST S +ST
Sbjct: 112 TETTMVSAMGSETTTNSTTSSETTVTST 139
>gi|119220598 apolipoprotein B48 receptor [Homo sapiens]
Length = 1088
Score = 57.4 bits (137), Expect = 3e-08
Identities = 83/368 (22%), Positives = 132/368 (35%), Gaps = 50/368 (13%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGT-----EVGRAGKGQHYEGSSHRQSQQ--G 143
E AE A G +E+G+ G + G +GT E G A G +S ++ G
Sbjct: 317 EEAETASGGEEAGTASGGEEAGIASGGEAGTASGGEEAGTASGGDEAWTTSGKEEADLLG 376
Query: 144 SRGQNRPGVQTQG--QATGSAWVSSYDRQAESQSQERISP---QIQLSGQTEQTQKAGEG 198
R V + +ATG WV + + + + + +SP Q Q+ G TE+T++A E
Sbjct: 377 VRQTEYGAVPGERLLEATGKVWV--LEEEGDEEREAEVSPFPKQPQVLG-TERTEEAAES 433
Query: 199 KRNQTTEMRPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQ 258
Q RE + GE+ G G + QD R +
Sbjct: 434 ------------QTAGREAVGGQEAGESF--EGQVDLRGKEAEMRQDLGI---RADRARM 476
Query: 259 EATNDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQ 318
E E G R ++ + G A+ A TP E++ + + S + QT
Sbjct: 477 EELVQAEEAQEERGSSRDPVAELPSDGEAEGTADLEA-TPEARPEEELTGEE-SEAAQTS 534
Query: 319 ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQ 378
G G H + Q + + G T + E E + + A + + +
Sbjct: 535 CGLLGVEWGGLTHSVTKGQGPELMGGAQTPTKQPEEREAGEVELMGVL----ALSKEEQE 590
Query: 379 TQPGSGQRWMQVSNPEAGETVPG------------GQAQTGASTESGRQEWSSTHPRRCV 426
+G R PEA E PG G Q A+ R+E + +
Sbjct: 591 RSLEAGPRHAGSVKPEASEAFPGAWENRTRKDMERGNTQEDAADGEQREEEETAGGQTLA 650
Query: 427 TEGQGDRQ 434
E +GDR+
Sbjct: 651 AEAEGDRE 658
>gi|5454034 S100 calcium-binding protein, beta [Homo sapiens]
Length = 92
Score = 53.9 bits (128), Expect = 3e-07
Identities = 27/85 (31%), Positives = 46/85 (54%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
M +L + + +I+ F +Y+ EG+ L + ELK L+ E + + + + VD+V+
Sbjct: 1 MSELEKAMVALIDVFHQYSGREGDKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMET 60
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQAC 85
LD D G +F+EF+ V V AC
Sbjct: 61 LDNDGDGECDFQEFMAFVAMVTTAC 85
>gi|5454032 S100 calcium binding protein A1 [Homo sapiens]
Length = 94
Score = 52.4 bits (124), Expect = 9e-07
Identities = 27/75 (36%), Positives = 45/75 (60%)
Query: 11 IIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVE 70
+I F ++ EG+ L++ ELK LL+ E + + D VD+V++ LDE+ G V+
Sbjct: 12 LINVFHAHSGKEGDKYKLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVD 71
Query: 71 FKEFLVLVFKVAQAC 85
F+E++VLV + AC
Sbjct: 72 FQEYVVLVAALTVAC 86
>gi|21614544 S100 calcium-binding protein A8 [Homo sapiens]
Length = 93
Score = 52.0 bits (123), Expect = 1e-06
Identities = 32/93 (34%), Positives = 50/93 (53%), Gaps = 4/93 (4%)
Query: 1 MPQLLQNINGIIEAFRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRL 60
+ +L + +N II+ + +Y+ +GN A+ R +LK+LLE E I K D +
Sbjct: 2 LTELEKALNSIIDVYHKYSLIKGNFHAVYRDDLKKLLETECPQYIRK----KGADVWFKE 57
Query: 61 LDEDHTGTVEFKEFLVLVFKVAQACFKTLSESA 93
LD + G V F+EFL+LV K+ A K E +
Sbjct: 58 LDINTDGAVNFQEFLILVIKMGVAAHKKSHEES 90
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/374 (17%), Positives = 131/374 (35%), Gaps = 14/374 (3%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSH-RQSQQGSRGQNR 149
+S G QE G+ G+ ++ + ++ E G+ + +S R+ R ++
Sbjct: 118 DSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK 177
Query: 150 P--GVQTQGQATGSAWVSS-YDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
P G TQ + WV D ++ + + S E + R + M
Sbjct: 178 PEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM 237
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
+ + + EQ +G + + + ++ + +E +D
Sbjct: 238 KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTE 297
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
+ + G SQ + G + +Q +Q V+ SS + + +QE N
Sbjct: 298 NSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQE--NSSES 355
Query: 327 GTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQR 386
E+ + R T + ++ +++ E+D S T+SH + + + S
Sbjct: 356 QEEVVSESRGDNPDPTT---SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 412
Query: 387 WMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDH 446
+PE+ E +Q G + S E S E D Q + +E D +
Sbjct: 413 NFSEESPESPED-ENSSSQEGLQSHSSSAESQSEESHS--EEDDSDSQDSSRSKE--DSN 467
Query: 447 SRETVILRLDQGNL 460
S E+ + G L
Sbjct: 468 STESKSSSEEDGQL 481
Score = 43.5 bits (101), Expect = 4e-04
Identities = 65/336 (19%), Positives = 118/336 (35%), Gaps = 40/336 (11%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSS----------- 136
T SES E + G S + E + G G+ H +GS
Sbjct: 161 TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDP 220
Query: 137 -HRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKA 195
+S++G+ N G++++ S ++ D SQ E S +I + +
Sbjct: 221 ESIRSERGNSRMNSAGMKSKESGENSEQANTQD-SGGSQLLEHPSRKIFRKSRISEEDDR 279
Query: 196 GEGKRNQTTEMRPERQPQTREQDRAHQTG--ETVTGSGTQTQAGATQTVEQDSSHQT-GR 252
E N T E E + + E + TG + S +Q + + + Q+ S G
Sbjct: 280 SELDDNNTME---EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGP 336
Query: 253 TSKQTQEAT-----NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSS 307
+S+ +QEA N E + R T + Q + + E+DSS
Sbjct: 337 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT-------SYVEDQEDSDSSEEDSS 389
Query: 308 HQTGSTSTQTQ---------ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
H + ++++ ES N E S + + + + ++ S
Sbjct: 390 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 449
Query: 359 EQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPE 394
E+D S + ++E + S + Q+ N E
Sbjct: 450 EEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 485
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 51.6 bits (122), Expect = 2e-06
Identities = 66/374 (17%), Positives = 131/374 (35%), Gaps = 14/374 (3%)
Query: 91 ESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSH-RQSQQGSRGQNR 149
+S G QE G+ G+ ++ + ++ E G+ + +S R+ R ++
Sbjct: 102 DSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDNEDRVDSK 161
Query: 150 P--GVQTQGQATGSAWVSS-YDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
P G TQ + WV D ++ + + S E + R + M
Sbjct: 162 PEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDPESIRSERGNSRMNSAGM 221
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNR 266
+ + + EQ +G + + + ++ + +E +D
Sbjct: 222 KSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTE 281
Query: 267 GTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTGSTSTQTQESTNGQNR 326
+ + G SQ + G + +Q +Q V+ SS + + +QE N
Sbjct: 282 NSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQE--NSSES 339
Query: 327 GTEIHGQGRSQTSQAVTGGHTQIQAGSHTETVEQDRSQTVSHGGAREQGQTQTQPGSGQR 386
E+ + R T + ++ +++ E+D S T+SH + + + S
Sbjct: 340 QEEVVSESRGDNPDPTT---SYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESL 396
Query: 387 WMQVSNPEAGETVPGGQAQTGASTESGRQEWSSTHPRRCVTEGQGDRQPTVVGEEWVDDH 446
+PE+ E +Q G + S E S E D Q + +E D +
Sbjct: 397 NFSEESPESPED-ENSSSQEGLQSHSSSAESQSEESHS--EEDDSDSQDSSRSKE--DSN 451
Query: 447 SRETVILRLDQGNL 460
S E+ + G L
Sbjct: 452 STESKSSSEEDGQL 465
Score = 43.5 bits (101), Expect = 4e-04
Identities = 65/336 (19%), Positives = 118/336 (35%), Gaps = 40/336 (11%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSS----------- 136
T SES E + G S + E + G G+ H +GS
Sbjct: 145 TTSESRELDNEDRVDSKPEGGDSTQESESEEHWVGGGSDGESSHGDGSELDDEGMQSDDP 204
Query: 137 -HRQSQQGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKA 195
+S++G+ N G++++ S ++ D SQ E S +I + +
Sbjct: 205 ESIRSERGNSRMNSAGMKSKESGENSEQANTQD-SGGSQLLEHPSRKIFRKSRISEEDDR 263
Query: 196 GEGKRNQTTEMRPERQPQTREQDRAHQTG--ETVTGSGTQTQAGATQTVEQDSSHQT-GR 252
E N T E E + + E + TG + S +Q + + + Q+ S G
Sbjct: 264 SELDDNNTME---EVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGP 320
Query: 253 TSKQTQEAT-----NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSS 307
+S+ +QEA N E + R T + Q + + E+DSS
Sbjct: 321 SSESSQEANLSSQENSSESQEEVVSESRGDNPDPTT-------SYVEDQEDSDSSEEDSS 373
Query: 308 HQTGSTSTQTQ---------ESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQAGSHTETV 358
H + ++++ ES N E S + + + + ++ S
Sbjct: 374 HTLSHSKSESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 433
Query: 359 EQDRSQTVSHGGAREQGQTQTQPGSGQRWMQVSNPE 394
E+D S + ++E + S + Q+ N E
Sbjct: 434 EEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLKNIE 469
>gi|91208420 bassoon protein [Homo sapiens]
Length = 3926
Score = 51.6 bits (122), Expect = 2e-06
Identities = 60/264 (22%), Positives = 91/264 (34%), Gaps = 25/264 (9%)
Query: 94 EGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRPGVQ 153
EG G S H G+ +G E GR H +++ S+ + P +
Sbjct: 3633 EGGPGRHASAKEHRHGDHGRHSGRHTGEEPGRRAAKPHARDLGRHEARPHSQPSSAPAMP 3692
Query: 154 TQGQATGSAWVSSYDRQAE-SQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEMRPERQP 212
+GQ Y AE SQ S S + +++A G ++ P+ QP
Sbjct: 3693 KKGQP-------GYPSSAEYSQPSRASSAYHHASDSKKGSRQAHSGPAALQSKAEPQAQP 3745
Query: 213 QTREQDRAHQTGETVTGSGTQTQAGATQTVEQDSSHQTGRTSKQTQEATNDQNRGTETHG 272
Q + + A ++ + S Q +GA Q Q G + Q+A
Sbjct: 3746 QLQGRQAAPGPQQSQSPSSRQIPSGAASRQPQTQQQQQGLGLQPPQQALTQAR------- 3798
Query: 273 QGRSQTSQAVTGGHAQIQAGTHTQTPTQTVEQDSSHQTG--STSTQTQESTNGQNRGTEI 330
Q SQ T G A P + S TG E TNG +
Sbjct: 3799 --LQQQSQPTTRGSAPA-----ASQPAGKPQPGPSTATGPQPAGPPRAEQTNGSKGTAKA 3851
Query: 331 HGQGRSQTSQAVTG-GHTQIQAGS 353
QGR+ +Q G G ++AG+
Sbjct: 3852 PQQGRAPQAQPAPGPGPAGVKAGA 3875
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 51.6 bits (122), Expect = 2e-06
Identities = 83/406 (20%), Positives = 134/406 (33%), Gaps = 34/406 (8%)
Query: 93 AEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYEGSSHRQSQQGSRGQNRP-- 150
+ GA + SGS S S + SG+ V G H S S N
Sbjct: 39 SSGASTATNSGS--SVTSSGVSTATISGSSVTSNGVSIVTNSEFHTTSSGISTATNSEFS 96
Query: 151 ----GVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRNQTTEM 206
G+ + S S S+S S + T +G +T
Sbjct: 97 TVSSGISIATNSESSTTSSGASTATNSESSTPSSGASTATNSDSSTTSSGA-----STAT 151
Query: 207 RPERQPQTREQDRAHQTGETVTGSGTQTQAGA-TQTVEQDSSHQTGRTSKQTQE----AT 261
+ + E A + + T SG T + + TV +S T S T AT
Sbjct: 152 NSDSSTTSSEASTATNSESSTTSSGASTATNSESSTVSSRASTATNSESSTTSSGASTAT 211
Query: 262 NDQNRGTETHGQGRSQTSQAVTGGHAQIQAGTHTQTP-----TQTVEQDSSHQTGS-TST 315
N ++R T + + + T A + + TP T T + S+ +G+ T+T
Sbjct: 212 NSESRTTSNGAGTATNSESSTTSSGASTATNSESSTPSSGAGTATNSESSTTSSGAGTAT 271
Query: 316 QTQESTNGQNRGTEIHGQGRSQTSQAVTGGHTQIQ-AGSHTETVEQDRSQTVSHGGAREQ 374
++ ST T + + + +S A T +++ S T S T S G +
Sbjct: 272 NSESSTVSSGISTVTNSESSTPSSGANTATNSESSTTSSGANTATNSDSSTTSSGASTAT 331
Query: 375 GQTQTQPGSGQRWMQVSNPEAGETVPG-------GQAQTGASTESGRQEWSSTHPRRCVT 427
+ SG +N E+ T G G + T + T + SST T
Sbjct: 332 NSESSTTSSGA--STATNSESSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSGAST 389
Query: 428 EGQGDRQPTVVGEEWVDDHSRETVILRLDQGNLHTSVSSAQGQDAA 473
+ T G + TV S +++ G + A
Sbjct: 390 ATTSESSTTSSGASTATNSESSTVSSGASTATNSESSTTSSGANTA 435
Score = 50.8 bits (120), Expect = 3e-06
Identities = 65/282 (23%), Positives = 107/282 (37%), Gaps = 21/282 (7%)
Query: 88 TLSESAEGACGSQESGSLHSGASQELGEGQRSGTEVGRAGKGQHYE------GSSHRQSQ 141
T+S A A S ES + SGAS R T AG + E G+S +
Sbjct: 187 TVSSRASTATNS-ESSTTSSGASTATNSESR--TTSNGAGTATNSESSTTSSGASTATNS 243
Query: 142 QGSRGQNRPGVQTQGQATGSAWVSSYDRQAESQSQERISPQIQLSGQTEQTQKAGEGKRN 201
+ S + G T +++ ++ + +ES + + S + + A +
Sbjct: 244 ESSTPSSGAGTATNSESSTTSSGAGTATNSESSTVSSGISTVTNSESSTPSSGANTATNS 303
Query: 202 QTTEMRPERQPQTREQDRAHQTG-ETVTGS-GTQTQAGATQTVEQDSSHQTGRTSKQTQE 259
+++ T +G T T S + T +GA+ +SS + S T
Sbjct: 304 ESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSESSTTSSGASTATNS 363
Query: 260 ATNDQNRGTETHGQGRSQT-----SQAVTGGHAQIQAG--THTQTPTQTVEQDSSHQTGS 312
++ + GT T S T S A T + +G T T + + TV +S T S
Sbjct: 364 GSSTTSSGTSTATNSESSTVSSGASTATTSESSTTSSGASTATNSESSTVSSGASTATNS 423
Query: 313 TSTQTQESTN-GQNRGTEIHGQGRSQTSQAVTGGHTQIQAGS 353
S+ T N N G+ + G + A+TG HT + S
Sbjct: 424 ESSTTSSGANTATNSGSSVTSAGSG--TAALTGMHTTSHSAS 463
>gi|4757898 calbindin 3 [Homo sapiens]
Length = 79
Score = 51.6 bits (122), Expect = 2e-06
Identities = 27/69 (39%), Positives = 45/69 (65%), Gaps = 3/69 (4%)
Query: 15 FRRYARTEGNCTALTRGELKRLLEQEFADVIVKPHDPATVDEVLRLLDEDHTGTVEFKEF 74
F +YA EG+ L++ ELK L++ EF ++ P+ T+D++ + LD++ G V F+EF
Sbjct: 14 FEKYAAKEGDPDQLSKDELKLLIQAEFPSLLKGPN---TLDDLFQELDKNGDGEVSFEEF 70
Query: 75 LVLVFKVAQ 83
VLV K++Q
Sbjct: 71 QVLVKKISQ 79
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.121 0.335
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,506,415
Number of Sequences: 37866
Number of extensions: 946228
Number of successful extensions: 4987
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 79
Number of HSP's successfully gapped in prelim test: 333
Number of HSP's that attempted gapping in prelim test: 3112
Number of HSP's gapped (non-prelim): 976
length of query: 495
length of database: 18,247,518
effective HSP length: 106
effective length of query: 389
effective length of database: 14,233,722
effective search space: 5536917858
effective search space used: 5536917858
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.