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Search of human proteins with 7705344
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]
(870 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens] 1731 0.0
gi|154350220 DNA polymerase iota [Homo sapiens] 128 2e-29
gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens] 107 4e-23
gi|7706681 REV1-like isoform 1 [Homo sapiens] 97 8e-20
gi|84043967 REV1-like isoform 2 [Homo sapiens] 96 1e-19
gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens] 37 0.061
gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens] 36 0.14
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 36 0.14
gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens] 36 0.14
gi|216548091 leucine zipper protein 1 [Homo sapiens] 36 0.14
gi|216548085 leucine zipper protein 1 [Homo sapiens] 36 0.14
gi|19924131 RAD50 homolog isoform 2 [Homo sapiens] 36 0.18
gi|19924129 RAD50 homolog isoform 1 [Homo sapiens] 36 0.18
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens] 34 0.52
gi|31542634 filamin A interacting protein 1 [Homo sapiens] 33 1.1
gi|224586823 coiled-coil domain containing 110 isoform b [Homo s... 33 1.5
gi|22749515 coiled-coil domain containing 110 isoform a [Homo sa... 33 1.5
gi|58331105 hypothetical protein LOC83932 isoform a [Homo sapiens] 33 1.5
gi|33946313 ninein isoform 4 [Homo sapiens] 32 2.0
gi|33946321 ninein isoform 5 [Homo sapiens] 32 2.0
gi|148536871 ninein isoform 1 [Homo sapiens] 32 2.0
gi|148536869 ninein isoform 2 [Homo sapiens] 32 2.0
gi|115527120 nebulin [Homo sapiens] 32 2.6
gi|41349476 PR domain containing 5 [Homo sapiens] 32 2.6
gi|19224660 protein kinase C and casein kinase substrate in neur... 32 2.6
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 32 2.6
gi|33300666 hypothetical protein LOC84895 [Homo sapiens] 32 2.6
gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens] 32 3.3
gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens] 32 3.3
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 32 3.3
>gi|7705344 DNA-directed DNA polymerase kappa [Homo sapiens]
Length = 870
Score = 1731 bits (4482), Expect = 0.0
Identities = 870/870 (100%), Positives = 870/870 (100%)
Query: 1 MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQV 60
MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQV
Sbjct: 1 MDSTKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQV 60
Query: 61 NQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDN 120
NQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDN
Sbjct: 61 NQRIENMMQQKAQITSQQLRKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDN 120
Query: 121 PELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE 180
PELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE
Sbjct: 121 PELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKE 180
Query: 181 VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNK 240
VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNK
Sbjct: 181 VKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDKRRYFIKMGSSVENDNPGKEVNK 240
Query: 241 LSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFR 300
LSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFR
Sbjct: 241 LSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQILQNSVVFGTSAQEVVKEIRFR 300
Query: 301 IEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV 360
IEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV
Sbjct: 301 IEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKV 360
Query: 361 TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVER 420
TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVER
Sbjct: 361 TEKMLKALGIITCTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVER 420
Query: 421 TFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVST 480
TFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVST
Sbjct: 421 TFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVST 480
Query: 481 AEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQAL 540
AEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQAL
Sbjct: 481 AEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQAL 540
Query: 541 SATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQ 600
SATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQ
Sbjct: 541 SATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQ 600
Query: 601 VLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSISENFKMFS 660
VLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSISENFKMFS
Sbjct: 601 VLKKKMNENLEISENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSISENFKMFS 660
Query: 661 CSHVSATKVNKKENVPASSLCEKQDYEAHPKIKEISSVDCIALVDTIDNSSKAESIDALS 720
CSHVSATKVNKKENVPASSLCEKQDYEAHPKIKEISSVDCIALVDTIDNSSKAESIDALS
Sbjct: 661 CSHVSATKVNKKENVPASSLCEKQDYEAHPKIKEISSVDCIALVDTIDNSSKAESIDALS 720
Query: 721 NKHSKEECSSLPSKSFNIEHCHQNSSSTVSLENEDVGSFRQEYRQPYLCEVKTGQALVCP 780
NKHSKEECSSLPSKSFNIEHCHQNSSSTVSLENEDVGSFRQEYRQPYLCEVKTGQALVCP
Sbjct: 721 NKHSKEECSSLPSKSFNIEHCHQNSSSTVSLENEDVGSFRQEYRQPYLCEVKTGQALVCP 780
Query: 781 VCNVEQKTSDLTLFNVHVDVCLNKSFIQELRKDKFNPVNQPKESSRSTGSSSGVQKAVTR 840
VCNVEQKTSDLTLFNVHVDVCLNKSFIQELRKDKFNPVNQPKESSRSTGSSSGVQKAVTR
Sbjct: 781 VCNVEQKTSDLTLFNVHVDVCLNKSFIQELRKDKFNPVNQPKESSRSTGSSSGVQKAVTR 840
Query: 841 TKRPGLMTKYSTSKKIKPNNPKHTLDIFFK 870
TKRPGLMTKYSTSKKIKPNNPKHTLDIFFK
Sbjct: 841 TKRPGLMTKYSTSKKIKPNNPKHTLDIFFK 870
>gi|154350220 DNA polymerase iota [Homo sapiens]
Length = 740
Score = 128 bits (322), Expect = 2e-29
Identities = 102/370 (27%), Positives = 173/370 (46%), Gaps = 47/370 (12%)
Query: 100 SNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTSNYHARRFGVRAAMPGFIAKR 159
S IVH+D+D FYA VEM NPELKDKP+ V ++ T NY AR+ GV+ M AK
Sbjct: 52 SRVIVHVDLDCFYAQVEMISNPELKDKPLGVQQKYLVVTCNYEARKLGVKKLMNVRDAKE 111
Query: 160 LCPQLIIV-PPNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQNWPEDK 218
CPQL++V + +YR +S +V E+L ++ P + DE ++++T+ +E+R +
Sbjct: 112 KCPQLVLVNGEDLTRYREMSYKVTELLEEFSPVVERLGFDENFVDLTEMVEKRLQQLQSD 171
Query: 219 RRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFEEQNNPQ 278
+ + V N+ + +N L
Sbjct: 172 ELSAVTVSGHVYNN---QSINLL------------------------------------D 192
Query: 279 ILQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPNGQYQILPN 338
+L ++ G+ ++ E+R + + LT AG+A N +LAK+ S KPN Q +LP
Sbjct: 193 VLHIRLLVGS---QIAAEMREAMYNQLGLTGCAGVASNKLLAKLVSGVFKPNQQTVLLP- 248
Query: 339 RQAVMDFIKDL-PIRKVSGIGKVTEKMLKALGIITCTELYQ-QRALLSLLFSETSWHYFL 396
++ I L I+++ GIG T K L+ALGI + +L +L +
Sbjct: 249 -ESCQHLIHSLNHIKEIPGIGYKTAKCLEALGINSVRDLQTFSPKILEKELGISVAQRIQ 307
Query: 397 HISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTV 456
+S G ++ + G +S S E +F + + E + +EL + L + ++ K TV
Sbjct: 308 KLSFGEDNSPVILSGPPQSFSEEDSFKKCSSEVEAKNKIEELLASLLNRVCQDGRKPHTV 367
Query: 457 TIKLKNVNFE 466
+ ++ + E
Sbjct: 368 RLIIRRYSSE 377
>gi|5729982 DNA-directed DNA polymerase eta [Homo sapiens]
Length = 713
Score = 107 bits (268), Expect = 4e-23
Identities = 169/652 (25%), Positives = 262/652 (40%), Gaps = 104/652 (15%)
Query: 106 IDMDAFYAAVEMRDNPELKDKPIAVGSMSM-----LSTSNYHARRFGVRAAMPGFIAKRL 160
+DMD F+ VE R NP L++KP AV + +Y AR FGV +M AK+L
Sbjct: 12 VDMDCFFVQVEQRQNPHLRNKPCAVVQYKSWKGGGIIAVSYEARAFGVTRSMWADDAKKL 71
Query: 161 CPQLIIVP-------PNFDKYRAVSKEVKEILADYDPNFMAMSLDEAYLNITKHLEERQN 213
CP L++ N KYR S EV EI++ + A S+DEAY+++T ++ER
Sbjct: 72 CPDLLLAQVRESRGKANLTKYREASVEVMEIMSRFAVIERA-SIDEAYVDLTSAVQERLQ 130
Query: 214 WPEDKRRYFIKMGSSVENDN-PGKEVNKLSEHERSISPLLFEESPSDVQPPGDPFQVNFE 272
+ G + D P + L + P EE+ VQ G Q F+
Sbjct: 131 KLQ---------GQPISADLLPSTYIEGLPQ-----GPTTAEET---VQKEGMRKQGLFQ 173
Query: 273 EQNNPQI--LQNSVVFGTSAQEVVKEIRFRIEQKTTLTASAGIAPNTMLAKVCSDKNKPN 330
++ QI L + + T +V+E+R IE++T SAGI+ N +LAK+ NKPN
Sbjct: 174 WLDSLQIDNLTSPDLQLTVGAVIVEEMRAAIERETGFQCSAGISHNKVLAKLACGLNKPN 233
Query: 331 GQYQILPNRQAVMDFIKDLPIRKVSGI-GKVTEKMLKALGIITCTELYQ-QRALLSLLFS 388
Q L + +V +PIRK+ + GK+ +++ LGI EL Q + L F
Sbjct: 234 --RQTLVSHGSVPQLFSQMPIRKIRSLGGKLGASVIEILGIEYMGELTQFTESQLQSHFG 291
Query: 389 ETSWHYFLHISLGLGSTHLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQ 444
E + + + G+ + K++ + F + + + Q+ L Q L EL +
Sbjct: 292 EKNGSWLYAMCRGIEHDPVKPRQLPKTIGCSKNFPGKTALATREQVQWWLLQ-LAQELEE 350
Query: 445 DLQKERLKGRTVTIKL---------KNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTE 495
L K+R V +L K ++ + A T + + F + K +
Sbjct: 351 RLTKDRNDNDRVATQLVVSIRVQGDKRLSSLRRCCALTRYDAHKMSHDAFTVIKNCNTSG 410
Query: 496 IDADFPHPL-RLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQALSATECTLEKTDKDK 554
I ++ PL L L + S+ I FL + +L T + K +
Sbjct: 411 IQTEWSPPLTMLFLCATKFSA-----SAPSSSTDITSFLSSDPSSLPKVPVTSSEA-KTQ 464
Query: 555 FVKPLEMSHKK------SFFDKKRSERKWSHQDTFKCEAVNKQ-----------SFQTSQ 597
P + KK SFF K +K A + FQTSQ
Sbjct: 465 GSGPAVTATKKATTSLESFFQKAAERQKVKEASLSSLTAPTQAPMSNSPSKPSLPFQTSQ 524
Query: 598 -----PF-----QVLKKKMNENLEISENS----DDCQIL----------TCPVCFRAQGC 633
PF +LK+K N +S +C+ L PVC +G
Sbjct: 525 STGTEPFFKQKSLLLKQKQLNNSSVSSPQQNPWSNCKALPNSLPTEYPGCVPVC---EGV 581
Query: 634 ISLEALNKHVDECLDGPSISENFKMFSCSHVSATKVNKKENVPASSLCEKQD 685
LE +K +D S++ S S S +V +K P SL +D
Sbjct: 582 SKLEESSKATPAEMDLAHNSQSMHASSASK-SVLEVTQKA-TPNPSLLAAED 631
>gi|7706681 REV1-like isoform 1 [Homo sapiens]
Length = 1251
Score = 96.7 bits (239), Expect = 8e-20
Identities = 101/394 (25%), Positives = 167/394 (42%), Gaps = 45/394 (11%)
Query: 80 RKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 139
R A + D M + S + I+H+DMD F+ +V +R+ P+LK KP+AV TS
Sbjct: 396 RSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAV-------TS 448
Query: 140 NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDE 199
N R +R PG P + +K +K AD + + + D
Sbjct: 449 NRGTGRAPLR---PG------------ANPQLEWQYYQNKILKGKAADIPDSSLWENPDS 493
Query: 200 AYLNITKHLEERQNWPE---DKRRYFIKMGSSVENDN---PGKEVNKLSEHE-RSISPLL 252
A N + R + R+ IK G + P + H + ++ L
Sbjct: 494 AQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTL 553
Query: 253 FEESPSDVQPPGDPFQVNFEEQNNPQILQN--SVVFGT--SAQEVVKEIRFRIEQKTTLT 308
+E S + N E + + L + ++ T + E +R I+ +T
Sbjct: 554 YETLAS--------YTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKCA 605
Query: 309 ASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKAL 368
AS GI N +LA++ + K KP+GQY + P + V DFI+ + + G+G E L +L
Sbjct: 606 ASVGIGSNILLARMATRKAKPDGQYHLKP--EEVDDFIRGQLVTNLPGVGHSMESKLASL 663
Query: 369 GIITCTEL-YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EIN 426
GI TC +L Y A L F + GL + + ERKS+S E +
Sbjct: 664 GIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFT 723
Query: 427 KAEEQYSLCQELCSELAQDLQKERLKGRTVTIKL 460
+ +E + L E+ + L+ +KG+ +T+K+
Sbjct: 724 QPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKI 757
>gi|84043967 REV1-like isoform 2 [Homo sapiens]
Length = 1250
Score = 95.9 bits (237), Expect = 1e-19
Identities = 101/394 (25%), Positives = 170/394 (43%), Gaps = 46/394 (11%)
Query: 80 RKAQLQVDRFAMELEQSRNLSNTIVHIDMDAFYAAVEMRDNPELKDKPIAVGSMSMLSTS 139
R A + D M + S + I+H+DMD F+ +V +R+ P+LK KP+AV TS
Sbjct: 396 RSALVVTDTGDMSVLNSPRHQSCIMHVDMDCFFVSVGIRNRPDLKGKPVAV-------TS 448
Query: 140 NYHARRFGVRAAMPGFIAKRLCPQLIIVPPNFDKYRAVSKEVKEILADYDPNFMAMSLDE 199
N R +R PG PQL +++ ++ + AD + + + D
Sbjct: 449 NRGTGRAPLR---PG-----ANPQL--------EWQYYQNKILKGKADIPDSSLWENPDS 492
Query: 200 AYLNITKHLEERQNWPE---DKRRYFIKMGSSVENDN---PGKEVNKLSEHE-RSISPLL 252
A N + R + R+ IK G + P + H + ++ L
Sbjct: 493 AQANGIDSVLSRAEIASCSYEARQLGIKNGMFFGHAKQLCPNLQAVPYDFHAYKEVAQTL 552
Query: 253 FEESPSDVQPPGDPFQVNFEEQNNPQILQN--SVVFGT--SAQEVVKEIRFRIEQKTTLT 308
+E S + N E + + L + ++ T + E +R I+ +T
Sbjct: 553 YETLAS--------YTHNIEAVSCDEALVDITEILAETKLTPDEFANAVRMEIKDQTKCA 604
Query: 309 ASAGIAPNTMLAKVCSDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKAL 368
AS GI N +LA++ + K KP+GQY + P + V DFI+ + + G+G E L +L
Sbjct: 605 ASVGIGSNILLARMATRKAKPDGQYHLKP--EEVDDFIRGQLVTNLPGVGHSMESKLASL 662
Query: 369 GIITCTEL-YQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFS-EIN 426
GI TC +L Y A L F + GL + + ERKS+S E +
Sbjct: 663 GIKTCGDLQYMTMAKLQKEFGPKTGQMLYRFCRGLDDRPVRTEKERKSVSAEINYGIRFT 722
Query: 427 KAEEQYSLCQELCSELAQDLQKERLKGRTVTIKL 460
+ +E + L E+ + L+ +KG+ +T+K+
Sbjct: 723 QPKEAEAFLLSLSEEIQRRLEATGMKGKRLTLKI 756
>gi|63252904 tropomyosin 1 alpha chain isoform 6 [Homo sapiens]
Length = 245
Score = 37.4 bits (85), Expect = 0.061
Identities = 33/125 (26%), Positives = 58/125 (46%), Gaps = 18/125 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ D +RK V R S++ +AEE+ L + C+EL ++L +TVT LK
Sbjct: 117 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-------KTVTNNLK 169
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEED 521
++ + + + EEI ++ +L + E A+F +L S + ED
Sbjct: 170 SLEAQAEKYSQKEDRY---EEEIKVLSDKLKEAETRAEFAERSVTKLE----KSIDDLED 222
Query: 522 RKHQQ 526
+ +QQ
Sbjct: 223 QLYQQ 227
>gi|63252902 tropomyosin 1 alpha chain isoform 2 [Homo sapiens]
Length = 284
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ D +RK V R S++ +AEE+ L + C+EL ++L +TVT LK
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-------KTVTNNLK 205
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI ++ +L + E A+F
Sbjct: 206 SLEAQAEKYSQKEDRY---EEEIKVLSDKLKEAETRAEF 241
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ D +RK V R S++ +AEE+ L + C+EL ++L +TVT LK
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-------KTVTNNLK 205
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI ++ +L + E A+F
Sbjct: 206 SLEAQAEKYSQKEDRY---EEEIKVLSDKLKEAETRAEF 241
>gi|63252896 tropomyosin 1 alpha chain isoform 3 [Homo sapiens]
Length = 284
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/99 (27%), Positives = 48/99 (48%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ D +RK V R S++ +AEE+ L + C+EL ++L +TVT LK
Sbjct: 153 HIAEDADRKYEEVARKLVIIESDLERAEERAELSEGKCAELEEEL-------KTVTNNLK 205
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI ++ +L + E A+F
Sbjct: 206 SLEAQAEKYSQKEDRY---EEEIKVLSDKLKEAETRAEF 241
>gi|216548091 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/121 (22%), Positives = 62/121 (51%), Gaps = 12/121 (9%)
Query: 406 HLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNF 465
+LTR+ + + +++ +E+ K EE +S + C++L L +ER + ++ +L+ +
Sbjct: 101 NLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRV 160
Query: 466 EVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ 525
+VK S+ + T + ++A EL K + L L V + NE++++++
Sbjct: 161 KVKELESSEDRLDKTEQ---SLASELEKLK---------SLTLSFVSERKYLNEKEKENE 208
Query: 526 Q 526
+
Sbjct: 209 K 209
>gi|216548085 leucine zipper protein 1 [Homo sapiens]
Length = 1076
Score = 36.2 bits (82), Expect = 0.14
Identities = 27/121 (22%), Positives = 62/121 (51%), Gaps = 12/121 (9%)
Query: 406 HLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNF 465
+LTR+ + + +++ +E+ K EE +S + C++L L +ER + ++ +L+ +
Sbjct: 101 NLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRV 160
Query: 466 EVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKHQ 525
+VK S+ + T + ++A EL K + L L V + NE++++++
Sbjct: 161 KVKELESSEDRLDKTEQ---SLASELEKLK---------SLTLSFVSERKYLNEKEKENE 208
Query: 526 Q 526
+
Sbjct: 209 K 209
>gi|19924131 RAD50 homolog isoform 2 [Homo sapiens]
Length = 1173
Score = 35.8 bits (81), Expect = 0.18
Identities = 45/224 (20%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 404 STHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNV 463
+ L D K ++ EI + EL SE+ Q E LKNV
Sbjct: 272 ANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE----------LKNV 321
Query: 464 NFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEE-DR 522
+E++ + ++ +E+ +EL K E +++ + + + + S NE+ D
Sbjct: 322 KYELQQLEGSSDRILELDQELIKAERELSKAEKNSN------VETLKMEVISLQNEKADL 375
Query: 523 KHQQRSIIGFL-QAGNQALSATE---CTLEKTDKDKFVKPLEMSHKK------SFFDKKR 572
R + + Q + + T+ T +K DKD+ ++ ++ H +F K+
Sbjct: 376 DRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 435
Query: 573 SERKWSHQDTFKCEAVNKQSFQTSQPFQVLKKKMNENLEISENS 616
W H K + +N+ + + K+N+ L SE +
Sbjct: 436 QLEDWLHS---KSKEINQTRDRLA--------KLNKELASSEQN 468
>gi|19924129 RAD50 homolog isoform 1 [Homo sapiens]
Length = 1312
Score = 35.8 bits (81), Expect = 0.18
Identities = 45/224 (20%), Positives = 88/224 (39%), Gaps = 38/224 (16%)
Query: 404 STHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNV 463
+ L D K ++ EI + EL SE+ Q E LKNV
Sbjct: 411 ANQLMNDFAEKETLKQKQIDEIRDKKTGLGRIIELKSEILSKKQNE----------LKNV 460
Query: 464 NFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEE-DR 522
+E++ + ++ +E+ +EL K E +++ + + + + S NE+ D
Sbjct: 461 KYELQQLEGSSDRILELDQELIKAERELSKAEKNSN------VETLKMEVISLQNEKADL 514
Query: 523 KHQQRSIIGFL-QAGNQALSATE---CTLEKTDKDKFVKPLEMSHKK------SFFDKKR 572
R + + Q + + T+ T +K DKD+ ++ ++ H +F K+
Sbjct: 515 DRTLRKLDQEMEQLNHHTTTRTQMEMLTKDKADKDEQIRKIKSRHSDELTSLLGYFPNKK 574
Query: 573 SERKWSHQDTFKCEAVNKQSFQTSQPFQVLKKKMNENLEISENS 616
W H K + +N+ + + K+N+ L SE +
Sbjct: 575 QLEDWLHS---KSKEINQTRDRLA--------KLNKELASSEQN 607
>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
Length = 1684
Score = 34.3 bits (77), Expect = 0.52
Identities = 47/217 (21%), Positives = 90/217 (41%), Gaps = 12/217 (5%)
Query: 407 LTRDGERKSMSVERT-FSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNF 465
L +D KS SV+ S + + EE+ ++ C E + + K +L +L +
Sbjct: 927 LLKDSLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRK 986
Query: 466 EVKTRASTVSSVVSTAEEIFAIAKELL------KTEIDADFPHPLRLRLMGVRISSFPNE 519
E +T + S+ S +++ A ++L+ K + +L + R ++F +
Sbjct: 987 ETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHR 1046
Query: 520 -EDRKHQQRSI---IGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSER 575
ED Q R+ + + N+ L A TL+ K V+ LE+ K+ DK+
Sbjct: 1047 IEDLTRQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAE 1106
Query: 576 KWSHQDTFKCEAVNKQSFQTSQ-PFQVLKKKMNENLE 611
K + K A + Q Q KK++ + ++
Sbjct: 1107 KLQKEQKIKEHATTVNELEELQVQLQKEKKQLQKTMQ 1143
Score = 32.3 bits (72), Expect = 2.0
Identities = 26/114 (22%), Positives = 54/114 (47%), Gaps = 17/114 (14%)
Query: 7 KCDSYKDDLLLRMGLNDNKAGMEGLDKE------KINKIIMEATKGSRFYGNELKKEKQV 60
K S K+D L + + K +E L+KE KINKI + A K + + K+ + V
Sbjct: 934 KSPSVKNDPLSSVKELEEK--IENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTV 991
Query: 61 NQRIENMMQQKAQIT---------SQQLRKAQLQVDRFAMELEQSRNLSNTIVH 105
+ +E++ +K Q++ ++ + L+ ++ + +L+ + +N H
Sbjct: 992 KEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEH 1045
>gi|31542634 filamin A interacting protein 1 [Homo sapiens]
Length = 1213
Score = 33.1 bits (74), Expect = 1.1
Identities = 51/230 (22%), Positives = 96/230 (41%), Gaps = 31/230 (13%)
Query: 406 HLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLKNVNF 465
H +++ + +++ SE+ K EE +S + C++L +L+KE + +T L N
Sbjct: 416 HHSKELRLEVEKLQKRMSELEKLEEAFSKSKSECTQLHLNLEKE----KNLTKDLLNELE 471
Query: 466 EVKTRASTVSSVVSTAEEI-FAIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEEDRKH 524
VK+R + S E+ ++ +L K + R +M E K
Sbjct: 472 VVKSRVKELECSESRLEKAELSLKDDLTKLKSFTVMLVDERKNMM----------EKIKQ 521
Query: 525 QQRSIIG----FLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQ 580
++R + G F + + TE +E++ K +K EM K ++R E
Sbjct: 522 EERKVDGLNKNFKVEQGKVMDVTEKLIEESKKLLKLKS-EMEEKVYNLTRERDEL----- 575
Query: 581 DTFKCEAVNKQSFQTSQPFQVLKKKMNENLEISE-----NSDDCQILTCP 625
K ++ ++S + S +LKK+++ E+ S LTCP
Sbjct: 576 -IGKLKSEEEKSSELSCSVDLLKKRLDGIEEVEREITRGRSRKGSELTCP 624
>gi|224586823 coiled-coil domain containing 110 isoform b [Homo
sapiens]
Length = 796
Score = 32.7 bits (73), Expect = 1.5
Identities = 80/434 (18%), Positives = 178/434 (41%), Gaps = 65/434 (14%)
Query: 200 AYLNITKH-LEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPS 258
++L+ TKH +++++ P + +K GS + + +VN ++E + L
Sbjct: 346 SFLDQTKHEMKDKERQP-----FLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 400
Query: 259 DVQPPGDPFQVNFEEQNNPQILQNSVVFGTSA-----QEVVKEIRFRIEQKTTLTASAGI 313
VQ ++ E N ++ ++F T + + K+++ +E+K+T+ + +
Sbjct: 401 SVQIQKKVMELESENLNLKSKMK-PLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSK--L 457
Query: 314 APNTMLAKVC-SDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIIT 372
+ +K C + K +Y +L + ++ K + ++M++AL +
Sbjct: 458 SKTEEYSKECLKEFKKIISKYNVLQGQNKTLE-------EKNIQLSLEKQQMMEALDQLK 510
Query: 373 CTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQY 432
E ++ ++ ++++ +E + + I + T++ + K M ++T + +
Sbjct: 511 SKE-HKTQSDMAIVNNENN---RMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKSSLG 566
Query: 433 SLCQELCSELAQDLQKERL---KGRTV-----TIKLKNVNFEVKTRAST----------- 473
+ +E E+ Q +KERL + T+ T+K + +N E + ST
Sbjct: 567 NELKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIE 626
Query: 474 -VSSVVSTAEEIF-----------AIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEED 521
+ + STAEE F +I K L +EI + ++ + + EE
Sbjct: 627 NIQTYQSTAEENFLQEIKNAKSEASIYKNSL-SEIGKECEMLSKMVMETKTDNQILKEEL 685
Query: 522 RKHQQRSIIGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQD 581
+KH Q +I S + T +K + +V+ +E F+ + +R++
Sbjct: 686 KKHSQENI-------KFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLS 738
Query: 582 TFKCEAVNKQSFQT 595
C N S T
Sbjct: 739 DKICNQHNDPSKTT 752
Score = 30.0 bits (66), Expect = 9.7
Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 30 GLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRF 89
G + E ++K++ME ++ ELKK Q N + EN + +L + ++ ++ +
Sbjct: 661 GKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSI--------SRLTEDKILLENY 712
Query: 90 AMELEQSRN 98
+E R+
Sbjct: 713 VRSIENERD 721
>gi|22749515 coiled-coil domain containing 110 isoform a [Homo
sapiens]
Length = 833
Score = 32.7 bits (73), Expect = 1.5
Identities = 80/434 (18%), Positives = 178/434 (41%), Gaps = 65/434 (14%)
Query: 200 AYLNITKH-LEERQNWPEDKRRYFIKMGSSVENDNPGKEVNKLSEHERSISPLLFEESPS 258
++L+ TKH +++++ P + +K GS + + +VN ++E + L
Sbjct: 383 SFLDQTKHEMKDKERQP-----FLVKQGSIISENEKTSKVNSVTEQCVAKIQYLQNYLKE 437
Query: 259 DVQPPGDPFQVNFEEQNNPQILQNSVVFGTSA-----QEVVKEIRFRIEQKTTLTASAGI 313
VQ ++ E N ++ ++F T + + K+++ +E+K+T+ + +
Sbjct: 438 SVQIQKKVMELESENLNLKSKMK-PLIFTTQSLIQKVETYEKQLKNLVEEKSTIQSK--L 494
Query: 314 APNTMLAKVC-SDKNKPNGQYQILPNRQAVMDFIKDLPIRKVSGIGKVTEKMLKALGIIT 372
+ +K C + K +Y +L + ++ K + ++M++AL +
Sbjct: 495 SKTEEYSKECLKEFKKIISKYNVLQGQNKTLE-------EKNIQLSLEKQQMMEALDQLK 547
Query: 373 CTELYQQRALLSLLFSETSWHYFLHISLGLGSTHLTRDGERKSMSVERTFSEINKAEEQY 432
E ++ ++ ++++ +E + + I + T++ + K M ++T + +
Sbjct: 548 SKE-HKTQSDMAIVNNENN---RMSIEMEAMKTNILLIQDEKEMLEKKTHQLLKEKSSLG 603
Query: 433 SLCQELCSELAQDLQKERL---KGRTV-----TIKLKNVNFEVKTRAST----------- 473
+ +E E+ Q +KERL + T+ T+K + +N E + ST
Sbjct: 604 NELKESQLEIIQLKEKERLAKTEQETLLQIIETVKDEKLNLETTLQESTAARQIMEREIE 663
Query: 474 -VSSVVSTAEEIF-----------AIAKELLKTEIDADFPHPLRLRLMGVRISSFPNEED 521
+ + STAEE F +I K L +EI + ++ + + EE
Sbjct: 664 NIQTYQSTAEENFLQEIKNAKSEASIYKNSL-SEIGKECEMLSKMVMETKTDNQILKEEL 722
Query: 522 RKHQQRSIIGFLQAGNQALSATECTLEKTDKDKFVKPLEMSHKKSFFDKKRSERKWSHQD 581
+KH Q +I S + T +K + +V+ +E F+ + +R++
Sbjct: 723 KKHSQENI-------KFENSISRLTEDKILLENYVRSIENERDTLEFEMRHLQREYLSLS 775
Query: 582 TFKCEAVNKQSFQT 595
C N S T
Sbjct: 776 DKICNQHNDPSKTT 789
Score = 30.0 bits (66), Expect = 9.7
Identities = 16/69 (23%), Positives = 34/69 (49%), Gaps = 8/69 (11%)
Query: 30 GLDKEKINKIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQQLRKAQLQVDRF 89
G + E ++K++ME ++ ELKK Q N + EN + +L + ++ ++ +
Sbjct: 698 GKECEMLSKMVMETKTDNQILKEELKKHSQENIKFENSI--------SRLTEDKILLENY 749
Query: 90 AMELEQSRN 98
+E R+
Sbjct: 750 VRSIENERD 758
>gi|58331105 hypothetical protein LOC83932 isoform a [Homo sapiens]
Length = 489
Score = 32.7 bits (73), Expect = 1.5
Identities = 15/40 (37%), Positives = 24/40 (60%), Gaps = 3/40 (7%)
Query: 613 SENSDDCQILTCPVCFRAQGCISLEALNKHVDECLDGPSI 652
S +S +++ CPVC Q + +N+H+D CL+G SI
Sbjct: 445 SSSSSQSKMVNCPVC---QNEVLESQINEHLDWCLEGDSI 481
>gi|33946313 ninein isoform 4 [Homo sapiens]
Length = 2096
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 3 STKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQ 62
S +K + K L+ ++D+ A +E ++ + K+ E + NEL+KE++ Q
Sbjct: 394 SDLDKAEKLKS--LMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE--Q 449
Query: 63 RIENMMQQKAQITSQQLRKAQLQV----DRFAMELEQSRNLSNTIV 104
++ +Q+ ++ Q++ KA+ + DR A+ L+++ L N ++
Sbjct: 450 ILQQAGKQRLEL-EQEIEKAKTEENYIRDRLALSLKENSRLENELL 494
>gi|33946321 ninein isoform 5 [Homo sapiens]
Length = 2090
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 3 STKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQ 62
S +K + K L+ ++D+ A +E ++ + K+ E + NEL+KE++ Q
Sbjct: 388 SDLDKAEKLKS--LMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE--Q 443
Query: 63 RIENMMQQKAQITSQQLRKAQLQV----DRFAMELEQSRNLSNTIV 104
++ +Q+ ++ Q++ KA+ + DR A+ L+++ L N ++
Sbjct: 444 ILQQAGKQRLEL-EQEIEKAKTEENYIRDRLALSLKENSRLENELL 488
>gi|148536871 ninein isoform 1 [Homo sapiens]
Length = 2046
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 3 STKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQ 62
S +K + K L+ ++D+ A +E ++ + K+ E + NEL+KE++ Q
Sbjct: 388 SDLDKAEKLKS--LMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE--Q 443
Query: 63 RIENMMQQKAQITSQQLRKAQLQV----DRFAMELEQSRNLSNTIV 104
++ +Q+ ++ Q++ KA+ + DR A+ L+++ L N ++
Sbjct: 444 ILQQAGKQRLEL-EQEIEKAKTEENYIRDRLALSLKENSRLENELL 488
>gi|148536869 ninein isoform 2 [Homo sapiens]
Length = 2133
Score = 32.3 bits (72), Expect = 2.0
Identities = 25/106 (23%), Positives = 56/106 (52%), Gaps = 9/106 (8%)
Query: 3 STKEKCDSYKDDLLLRMGLNDNKAGMEGLDKEKINKIIMEATKGSRFYGNELKKEKQVNQ 62
S +K + K L+ ++D+ A +E ++ + K+ E + NEL+KE++ Q
Sbjct: 388 SDLDKAEKLKS--LMASEVDDHHAAIERRNEYNLRKLDEEYKERIAALKNELRKERE--Q 443
Query: 63 RIENMMQQKAQITSQQLRKAQLQV----DRFAMELEQSRNLSNTIV 104
++ +Q+ ++ Q++ KA+ + DR A+ L+++ L N ++
Sbjct: 444 ILQQAGKQRLEL-EQEIEKAKTEENYIRDRLALSLKENSRLENELL 488
>gi|115527120 nebulin [Homo sapiens]
Length = 6669
Score = 32.0 bits (71), Expect = 2.6
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 668 KVNKKENVPASSLCEKQDYEAHPKIKEISSVDCIALVDTIDNSSKAESIDALSNKHSKEE 727
K+NKK V AS + K+DYE K K + + + + + DALS+K KE
Sbjct: 334 KMNKKAGVAASKVKYKEDYE---KNKGKADYNVLPASENPQLRQLKAAGDALSDKLYKEN 390
Query: 728 CSSLPSKSFNIEHCHQNSSSTVSLENEDVGSFRQEYRQPYLCEV 771
+KS N + TV L+N S ++Y+ YL ++
Sbjct: 391 YEKTKAKSINYCETPKFKLDTV-LQN---FSSDKKYKDSYLKDI 430
>gi|41349476 PR domain containing 5 [Homo sapiens]
Length = 630
Score = 32.0 bits (71), Expect = 2.6
Identities = 29/116 (25%), Positives = 46/116 (39%), Gaps = 16/116 (13%)
Query: 637 EALNKHVDECLDGPSISENFKMFSCSHVSATKVNKKENVPASSLCEKQDYEAHPKIKEIS 696
+AL +HV +C S+ E+ + F CS V SS +E H +E
Sbjct: 212 QALQRHVLQCTAKSSLKESSRSFQCS------------VCNSSFSSASSFEQH---QETC 256
Query: 697 SVDCIALVDTIDNSSKAESIDALSNKHSKEECSSLPSKSFNIEHCHQNSSSTVSLE 752
D + + +S DAL +H + + P K C++ SS SL+
Sbjct: 257 RGDARFVCKADSCGKRLKSKDAL-KRHQENVHTGDPKKKLICSVCNKKCSSASSLQ 311
>gi|19224660 protein kinase C and casein kinase substrate in neurons
3 [Homo sapiens]
Length = 424
Score = 32.0 bits (71), Expect = 2.6
Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%)
Query: 20 GLNDNKAGMEGLDKEKIN--KIIMEATKGSRFYGNELKKEKQVNQRIENMMQQKAQITSQ 77
G +++A +G K + K + E + Y K EK R E+ + + ++ +
Sbjct: 125 GFRESRAAEDGFRKAQKPWLKRLKEVEASKKSYHAARKDEKTAQTR-ESHAKADSAVSQE 183
Query: 78 QLRKAQLQVDRFAMELEQSR 97
QLRK Q +V+R A E E+++
Sbjct: 184 QLRKLQERVERCAKEAEKTK 203
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 32.0 bits (71), Expect = 2.6
Identities = 47/190 (24%), Positives = 79/190 (41%), Gaps = 36/190 (18%)
Query: 436 QELCSELAQDLQKERLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTE 495
++ C+EL +D+ +KL E K + +T + V + EE+ A+ + +
Sbjct: 993 EDECTELKKDIDD---------LKLTLAKAE-KEKQATENKVKNLTEEMAALDESV---- 1038
Query: 496 IDADFPHPLRLRLMGVRISSFPNEEDRKHQQRSIIGFLQAGNQALSATECTLEKTDKDKF 555
R++ HQQ +G LQA +SA T K ++
Sbjct: 1039 ---------------ARLTKEKKALQEAHQQA--LGDLQAEEDRVSAL--TKAKLRLEQQ 1079
Query: 556 VKPLEMS---HKKSFFDKKRSERKWSHQDTFKCEAVNKQSFQTSQPFQVLKKKMNENLEI 612
V+ LE S KK D +R++RK E+V + Q + LKKK +E ++
Sbjct: 1080 VEDLECSLEQEKKLRMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKDSELSQL 1139
Query: 613 SENSDDCQIL 622
S +D Q+L
Sbjct: 1140 SLRVEDEQLL 1149
>gi|33300666 hypothetical protein LOC84895 [Homo sapiens]
Length = 593
Score = 32.0 bits (71), Expect = 2.6
Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 15/132 (11%)
Query: 386 LFSETSWHYFLHISLGL----GSTHLTRDGERKSMSVERTFSEINKAEEQYSLCQELCSE 441
LF E + +S+G GST + RDG R + SE ++++ E
Sbjct: 183 LFEEALQKWEQALSVGQRGDSGSTPMPRDGLRNPETASEPLSEPESQRKEFAEKLESLLH 242
Query: 442 LAQDLQKE---------RLKGRTVTIKLKNVNFEVKTRASTVSSVVSTAEEIFAIAKELL 492
A LQ+E L T+ L ++ RA S+ T+E+ F A EL
Sbjct: 243 RAYHLQEEFGSTFPADSMLLDLERTLMLPLTEGSLRLRADDEDSL--TSEDSFFSATELF 300
Query: 493 KTEIDADFPHPL 504
++ D+P PL
Sbjct: 301 ESLQTGDYPIPL 312
>gi|114155148 tropomyosin 3 isoform 5 [Homo sapiens]
Length = 247
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ + +RK V R ++ + EE+ L + CSEL ++L + VT LK
Sbjct: 117 HIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL-------KNVTNNLK 169
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI + +L + E A+F
Sbjct: 170 SLEAQAEKYSQKEDKY---EEEIKILTDKLKEAETRAEF 205
>gi|114155144 tropomyosin 3 isoform 4 [Homo sapiens]
Length = 248
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ + +RK V R ++ + EE+ L + CSEL ++L + VT LK
Sbjct: 117 HIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL-------KNVTNNLK 169
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI + +L + E A+F
Sbjct: 170 SLEAQAEKYSQKEDKY---EEEIKILTDKLKEAETRAEF 205
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 31.6 bits (70), Expect = 3.3
Identities = 24/99 (24%), Positives = 44/99 (44%), Gaps = 14/99 (14%)
Query: 406 HLTRDGERKSMSVERTF----SEINKAEEQYSLCQELCSELAQDLQKERLKGRTVTIKLK 461
H+ + +RK V R ++ + EE+ L + CSEL ++L + VT LK
Sbjct: 154 HIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL-------KNVTNNLK 206
Query: 462 NVNFEVKTRASTVSSVVSTAEEIFAIAKELLKTEIDADF 500
++ + + + EEI + +L + E A+F
Sbjct: 207 SLEAQAEKYSQKEDKY---EEEIKILTDKLKEAETRAEF 242
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.365
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,132,457
Number of Sequences: 37866
Number of extensions: 1347875
Number of successful extensions: 4984
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 54
Number of HSP's that attempted gapping in prelim test: 4898
Number of HSP's gapped (non-prelim): 142
length of query: 870
length of database: 18,247,518
effective HSP length: 111
effective length of query: 759
effective length of database: 14,044,392
effective search space: 10659693528
effective search space used: 10659693528
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.