Guide to the Human Genome
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Search of human proteins with 7705266

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7705266 NCK interacting protein with SH3 domain isoform 1
[Homo sapiens]
         (722 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Ho...  1429   0.0  
gi|37577148 NCK interacting protein with SH3 domain isoform 2 [H...  1409   0.0  
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        54   7e-07
gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]         50   7e-06
gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]       49   2e-05
gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]       48   3e-05
gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]        48   3e-05
gi|130977759 tec protein tyrosine kinase [Homo sapiens]                48   4e-05
gi|20143482 melanoma antigen family E, 1 [Homo sapiens]                47   6e-05
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]                 46   1e-04
gi|158534059 formin binding protein 4 [Homo sapiens]                   46   1e-04
gi|38683860 insulin receptor substrate 2 [Homo sapiens]                45   2e-04
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         45   2e-04
gi|148596974 TXK tyrosine kinase [Homo sapiens]                        45   2e-04
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    45   3e-04
gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo sap...    44   4e-04
gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo sapi...    44   4e-04
gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo...    44   4e-04
gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo...    44   4e-04
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]               44   4e-04
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]               44   4e-04
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]                44   4e-04
gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo sap...    44   4e-04
gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo sap...    44   4e-04
gi|189181724 proteoglycan 4 isoform D [Homo sapiens]                   44   7e-04
gi|189181722 proteoglycan 4 isoform C [Homo sapiens]                   44   7e-04
gi|189181720 proteoglycan 4 isoform B [Homo sapiens]                   44   7e-04
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    44   7e-04
gi|67190163 proteoglycan 4 isoform A [Homo sapiens]                    44   7e-04
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    44   7e-04

>gi|7705266 NCK interacting protein with SH3 domain isoform 1 [Homo
           sapiens]
          Length = 722

 Score = 1429 bits (3700), Expect = 0.0
 Identities = 722/722 (100%), Positives = 722/722 (100%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE
Sbjct: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60

Query: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120
           QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS
Sbjct: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120

Query: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT 180
           TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT
Sbjct: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT 180

Query: 181 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 240
           TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS
Sbjct: 181 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 240

Query: 241 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 300
           PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE
Sbjct: 241 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 300

Query: 301 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 360
           KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL
Sbjct: 301 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 360

Query: 361 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 420
           VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI
Sbjct: 361 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 420

Query: 421 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 480
           LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS
Sbjct: 421 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 480

Query: 481 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 540
           SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED
Sbjct: 481 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 540

Query: 541 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 600
           GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP
Sbjct: 541 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 600

Query: 601 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 660
           VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY
Sbjct: 601 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 660

Query: 661 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 720
           LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA
Sbjct: 661 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 720

Query: 721 PS 722
           PS
Sbjct: 721 PS 722


>gi|37577148 NCK interacting protein with SH3 domain isoform 2 [Homo
           sapiens]
          Length = 715

 Score = 1409 bits (3647), Expect = 0.0
 Identities = 715/722 (99%), Positives = 715/722 (99%), Gaps = 7/722 (0%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE
Sbjct: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60

Query: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120
           QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS
Sbjct: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120

Query: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPT 180
           TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP       PQPRRAAPT
Sbjct: 121 TSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP-------PQPRRAAPT 173

Query: 181 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 240
           TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS
Sbjct: 174 TPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS 233

Query: 241 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 300
           PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE
Sbjct: 234 PTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 293

Query: 301 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 360
           KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL
Sbjct: 294 KAAAEAAVPRTIGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSPVMEQVLLSL 353

Query: 361 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 420
           VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI
Sbjct: 354 VEGKDLSMALPSGQVCHDQQRLEVIFADLARRKDDAQQRSWALYEDEGVIRCYLEELLHI 413

Query: 421 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 480
           LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS
Sbjct: 414 LTDADPEVCKKMCKRNEFESVLALVAYYQMEHRASLRLLLLKCFGAMCSLDAAIISTLVS 473

Query: 481 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 540
           SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED
Sbjct: 474 SVLPVELARDMQTDTQDHQKLCYSALILAMVFSMGEAVPYAHYEHLGTPFAQFLLNIVED 533

Query: 541 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 600
           GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP
Sbjct: 534 GLPLDTTEQLPDLCVNLLLALNLHLPAADQNVIMAALSKHANVKIFSEKLLLLLNRGDDP 593

Query: 601 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 660
           VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY
Sbjct: 594 VRIFKHEPQPPHSVLKFLQDVFGSPATAAIFYHTDMMALIDITVRHIADLSPGDKLRMEY 653

Query: 661 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 720
           LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA
Sbjct: 654 LSLMHAIVRTTPYLQHRHRLPDLQAILRRILNEEETSPQCQMDRMIVREMCKEFLVLGEA 713

Query: 721 PS 722
           PS
Sbjct: 714 PS 715


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 54/205 (26%), Positives = 81/205 (39%), Gaps = 26/205 (12%)

Query: 106  RRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPL 165
            RR  S+SS +  +SS+S     ++++        +G     S  SS  +  +  L ++P 
Sbjct: 2530 RRSSSSSSSSSSSSSSSSSSSSSSSS--------SGSSSSDSEGSSLPVQPEVALKRVPS 2581

Query: 166  PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
            P+       R   P  P P  ++R   +  +S S   ++  S  +S SS SS SS+S   
Sbjct: 2582 PTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS--- 2638

Query: 226  LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASD 285
               SSS S   SS SP  P              Q  P  AS  +PP  E  +       D
Sbjct: 2639 ---SSSSSSSSSSPSPAKP------------GPQALPKPASPKKPPPGERRSRSPRKPID 2683

Query: 286  DLEALGTLSLGTTEEKAAAEAAVPR 310
             L    +LS    E +  +    PR
Sbjct: 2684 SLRDSRSLSYSPVERRRPSPQPSPR 2708



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 48/206 (23%), Positives = 75/206 (36%), Gaps = 31/206 (15%)

Query: 105 SRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP 164
           SRR   ++S    +SS +      +AA + +    AG   +   P+S   G     +  P
Sbjct: 257 SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAG---RSPSPASGRRGEGDAPFSEP 313

Query: 165 LPSSQIPPQPRRAAPTTPPPPVKRRDREALMASG---------SGGHNTMPSGGNSVSSG 215
             +S   P     A   P  P + +D++    S          S      P+    ++  
Sbjct: 314 GTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAER 373

Query: 216 SSVSSTSLDTLYTSSSPSEPGSSCSPT----PPPVPRRGTHTTVSQVQPP---PSKAS-- 266
              S   L T   S  P  P S  SPT    PP  P +   ++ S+  PP   P+K S  
Sbjct: 374 HGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRH 433

Query: 267 ----------APEPPAEEEVATGTTS 282
                     AP P +  E+++  TS
Sbjct: 434 ASSSPESPKPAPAPGSHREISSSPTS 459



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 47/199 (23%), Positives = 81/199 (40%), Gaps = 32/199 (16%)

Query: 110  SASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQ 169
            S+ +VA  TSS  DH          NG+         S+P+     +D G      P+S 
Sbjct: 2476 SSGAVATTTSSAGDH----------NGML--------SVPAPGVPHSDVG----EPPAST 2513

Query: 170  IPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTS 229
               QP   A   P    +RR   +  +S S   ++  S  +S SSGSS S +       S
Sbjct: 2514 GAQQPSALAALQPAK--ERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSE-----GS 2566

Query: 230  SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPP-PSKASAPEPPAEEEVATGTTSASDDLE 288
            S P +P  +    P P P       V + +PP P+ A      +    ++ ++S+S    
Sbjct: 2567 SLPVQPEVALKRVPSPTP--APKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSS 2624

Query: 289  ALGTLSLGTTEEKAAAEAA 307
            +  + S  ++   +++ ++
Sbjct: 2625 SSSSSSSSSSSSSSSSSSS 2643



 Score = 35.4 bits (80), Expect = 0.19
 Identities = 39/182 (21%), Positives = 70/182 (38%), Gaps = 7/182 (3%)

Query: 109  PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSS 168
            PSA ++A   + T+   ++ A AR P  +         + P++ +  +     Q P  ++
Sbjct: 2279 PSAVNLADPRTPTAPA-VNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASAN 2337

Query: 169  QIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYT 228
             + P  R A  T P      R   AL  +        P+   +  +   V  ++ + +  
Sbjct: 2338 LVGP--RSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG 2395

Query: 229  SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPE----PPAEEEVATGTTSAS 284
             +SP     + S TPP  P +   T+     P      AP     PPA+++  +   SA 
Sbjct: 2396 RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAF 2455

Query: 285  DD 286
             D
Sbjct: 2456 SD 2457



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 47/218 (21%), Positives = 74/218 (33%), Gaps = 50/218 (22%)

Query: 99  HRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADG 158
           ++  T  RR  S SS  +  S  S     + ++ +     R    R  S           
Sbjct: 732 NKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLS----------- 780

Query: 159 GLYQIPLPSSQIPPQ----------------PRRAAPTTPPPPVKRRDREALMASGSGGH 202
           G    P   SQ PP+                PRR+  ++ PPP ++    +  +  S   
Sbjct: 781 GSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSP 840

Query: 203 NTMPSGGNSVSSGSSVS----------------STSLDTLYTSSSPSEPGSSCSPTPPPV 246
           +     G     GS  S                 +S D    S +PS    SCS + PP 
Sbjct: 841 HPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSR--HSCSGSSPPR 898

Query: 247 PRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSAS 284
            +  T    S     PS++S+P+P  +  ++    S S
Sbjct: 899 VKSSTPPRQS-----PSRSSSPQPKVKAIISPRQRSHS 931



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 35/116 (30%), Positives = 48/116 (41%), Gaps = 15/116 (12%)

Query: 164  PLPSSQIPPQPRRAAPTTPPPPVK-----RRDREALMASGSGGH---NTMPSGGNSVSSG 215
            P   S  PP+   +  ++P P VK     R+   +  +S S       T P    SVS  
Sbjct: 897  PRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPC 956

Query: 216  SSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPP 271
            S+V S  L   Y+ S  S P +   P  PP   R +H+    + P P K  A  PP
Sbjct: 957  SNVESRLLPR-YSHSGSSSPDTKVKPETPP---RQSHS--GSISPYP-KVKAQTPP 1005



 Score = 33.9 bits (76), Expect = 0.54
 Identities = 43/170 (25%), Positives = 57/170 (33%), Gaps = 7/170 (4%)

Query: 100  RKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGG 159
            RK  LSRR  SASS     S T   H  + +   P    ++   R+    SS        
Sbjct: 1699 RKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSR 1758

Query: 160  LYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSV---SSGS 216
              + P P  +   + R  +        +RRDR     S S       S          GS
Sbjct: 1759 RGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGS 1818

Query: 217  SVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKAS 266
               S S     +S + S      S TPP   +R      S+  P P K S
Sbjct: 1819 GYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSR----SRTSPAPWKRS 1864



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 39/190 (20%), Positives = 77/190 (40%), Gaps = 21/190 (11%)

Query: 117  MTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQPRR 176
            ++  TS   LD A +R P            S PS   + ++    + P PSS++   P +
Sbjct: 2393 VSGRTSPPLLDRARSRTPP-----------SAPSQSRMTSE----RAPSPSSRMGQAPSQ 2437

Query: 177  AAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPG 236
            +      PP + + R  + ++ S     + +    V+   S+SS ++ T  T+SS  +  
Sbjct: 2438 SLL----PPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVAT--TTSSAGDHN 2491

Query: 237  SSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLG 296
               S   P VP        +        A A   PA+E  ++ ++S+S    +  + S  
Sbjct: 2492 GMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSS 2551

Query: 297  TTEEKAAAEA 306
            ++    ++ +
Sbjct: 2552 SSSSSGSSSS 2561



 Score = 33.5 bits (75), Expect = 0.71
 Identities = 35/153 (22%), Positives = 58/153 (37%), Gaps = 2/153 (1%)

Query: 103  TLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQ 162
            T ++R   +SS +  +SS+S     ++++   +    +      S  SS    A  G   
Sbjct: 2599 TPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQA 2658

Query: 163  IPLPSSQIPPQPRRAAPTTPPPPV-KRRDREALMASGSGGHNTMPS-GGNSVSSGSSVSS 220
            +P P+S   P P      +P  P+   RD  +L  S        P        S SS   
Sbjct: 2659 LPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERG 2718

Query: 221  TSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHT 253
            +       S SPS      +P+P P+  R + +
Sbjct: 2719 SRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRS 2751



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 45/191 (23%), Positives = 64/191 (33%), Gaps = 19/191 (9%)

Query: 100 RKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGG 159
           R  T +RRG S S      S  S     A   R  +   R G  R  SL           
Sbjct: 659 RSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGR------ 712

Query: 160 LYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGH----NTMPSGGNSVSSG 215
                  S    PQ R  + ++     K R  +    S S               S+SS 
Sbjct: 713 -------SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSP 765

Query: 216 SSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPP--SKASAPEPPAE 273
            S + + L    + S  S      S TPP   R G+    ++ + PP  S++S+  PP +
Sbjct: 766 RSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQ 825

Query: 274 EEVATGTTSAS 284
           +       S S
Sbjct: 826 KSKTPSRQSHS 836



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 24/87 (27%), Positives = 33/87 (37%)

Query: 168  SQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLY 227
            S+ PP  RR + +  PP  +RR R            +  S      S S  S  +     
Sbjct: 1948 SRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSR 2007

Query: 228  TSSSPSEPGSSCSPTPPPVPRRGTHTT 254
            + +SP     S S TPP + RR    T
Sbjct: 2008 SRTSPVTRRRSRSRTPPAIRRRSRSRT 2034


>gi|42542379 serine/arginine repetitive matrix 1 [Homo sapiens]
          Length = 904

 Score = 50.1 bits (118), Expect = 7e-06
 Identities = 46/170 (27%), Positives = 59/170 (34%), Gaps = 7/170 (4%)

Query: 146 HSLPSSEHLGADGGLYQIPLPSSQIPPQPRRAAPTT--PPPPVKRRDREALMASGSGGHN 203
           H+ P   H            PS +  P PRR  P    PPPP  RR R  +        +
Sbjct: 295 HTRPRRRHRSRSRSYSPRRRPSPRRRPSPRRRTPPRRMPPPPRHRRSRSPVRRRRRSSAS 354

Query: 204 TMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPS 263
              SG +S SS S   S        +SSP       SP+  P  RR  H       PPP 
Sbjct: 355 L--SGSSSSSSSSRSRSPPKKPPKRTSSPPRKTRRLSPSASPPRRR--HRPSPPATPPPK 410

Query: 264 KASAPEPPAEEEVATGTTSASDD-LEALGTLSLGTTEEKAAAEAAVPRTI 312
              +P P           S S        T   GT + ++ + A  PR +
Sbjct: 411 TRHSPTPQQSNRTRKSRVSVSPGRTSGKVTKHKGTEKRESPSPAPKPRKV 460



 Score = 38.9 bits (89), Expect = 0.017
 Identities = 35/140 (25%), Positives = 55/140 (39%), Gaps = 15/140 (10%)

Query: 171 PPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSS 230
           PP  RR +P+  PPP +RR       +      T        S      S  +   Y   
Sbjct: 553 PPTRRRRSPSPAPPPRRRR-----TPTPPPRRRTPSPPPRRRSPSPRRYSPPIQRRY--- 604

Query: 231 SPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEAL 290
           SPS P    + +PPP P+R      +   PPP +  +  PP ++  +  T   S  L + 
Sbjct: 605 SPSPPPKRRTASPPPPPKRR-----ASPSPPPKRRVSHSPPPKQRSSPVTKRRSPSLSS- 658

Query: 291 GTLSLGTTEEKAAAEAAVPR 310
                G++  ++  EA  P+
Sbjct: 659 -KHRKGSSPSRSTREARSPQ 677



 Score = 38.5 bits (88), Expect = 0.022
 Identities = 38/132 (28%), Positives = 52/132 (39%), Gaps = 16/132 (12%)

Query: 164 PLPSSQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNS-------VSS 214
           P P+ +  P PR  AP T   PPPV+R    +     S   +T P    S       +  
Sbjct: 676 PQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPSPSTRPIRRVSRTPEPKKIKK 735

Query: 215 GSSVSSTSLDTLYTSSSPS---EPGSSCSPTPP-PVPRRGTHTTVSQVQP---PPSKASA 267
            +S S  S+  + +S S S   EP +   P PP PV  +   T  S   P     S   +
Sbjct: 736 AASPSPQSVRRVSSSRSVSGSPEPAAKKPPAPPSPVQSQSPSTNWSPAVPVKKAKSPTPS 795

Query: 268 PEPPAEEEVATG 279
           P PP   +   G
Sbjct: 796 PSPPRNSDQEGG 807



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 42/180 (23%), Positives = 70/180 (38%), Gaps = 26/180 (14%)

Query: 161 YQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGN---------S 211
           Y  P+     P  P +    +PPPP KRR   +        H+  P   +         S
Sbjct: 596 YSPPIQRRYSPSPPPKRRTASPPPPPKRRASPSPPPKRRVSHSPPPKQRSSPVTKRRSPS 655

Query: 212 VSS----GSSVSSTSLDTLYT------SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPP 261
           +SS    GSS S ++ +          S SP       S +PPPV R  + +   +  P 
Sbjct: 656 LSSKHRKGSSPSRSTREARSPQPNKRHSPSPRPRAPQTSSSPPPVRRGASSSPQRRQSPS 715

Query: 262 PSK------ASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAE 315
           PS       +  PEP   ++ A+ +  +   + +  ++S G+ E  A    A P  + ++
Sbjct: 716 PSTRPIRRVSRTPEPKKIKKAASPSPQSVRRVSSSRSVS-GSPEPAAKKPPAPPSPVQSQ 774


>gi|23510362 protein-tyrosine kinase fyn isoform b [Homo sapiens]
          Length = 534

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 43/177 (24%), Positives = 70/177 (39%), Gaps = 14/177 (7%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVAVMTSS 120
            +         +      +  G       RG    LI   +E+ + +G  + S+      
Sbjct: 146 AEEWYFGKLGRKDAERQLLSFG-----NPRGTF--LI---RESETTKGAYSLSIRDWDDM 195

Query: 121 TSDHHLDAAAARQPNG----VCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQIPPQ 173
             DH       +  NG      RA FE    L       ADG  + + + +S   PQ
Sbjct: 196 KGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSEKADGLCFNLTVIASSCTPQ 252


>gi|23510364 protein-tyrosine kinase fyn isoform c [Homo sapiens]
          Length = 482

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QD 62
            +
Sbjct: 146 AE 147


>gi|4503823 protein-tyrosine kinase fyn isoform a [Homo sapiens]
          Length = 537

 Score = 48.1 bits (113), Expect = 3e-05
 Identities = 20/62 (32%), Positives = 34/62 (54%)

Query: 1   MYRALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYLRRLQGLE 60
           ++ ALY + +   + L+F  GE F +L  S   WW A    +GETGY+P  Y+  +  ++
Sbjct: 86  LFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYIPSNYVAPVDSIQ 145

Query: 61  QD 62
            +
Sbjct: 146 AE 147


>gi|130977759 tec protein tyrosine kinase [Homo sapiens]
          Length = 631

 Score = 47.8 bits (112), Expect = 4e-05
 Identities = 20/50 (40%), Positives = 32/50 (64%), Gaps = 1/50 (2%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           A+Y F++AE + L    G+ +L+LE++  HWW  AR + G  GY+P  Y+
Sbjct: 186 AMYDFQAAEGHDLRLERGQEYLILEKNDVHWW-RARDKYGNEGYIPSNYV 234


>gi|20143482 melanoma antigen family E, 1 [Homo sapiens]
          Length = 957

 Score = 47.0 bits (110), Expect = 6e-05
 Identities = 57/226 (25%), Positives = 88/226 (38%), Gaps = 24/226 (10%)

Query: 102 ETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY 161
           E LS  GP   S  + TS T    L A+  R  +    +  E   S+P +          
Sbjct: 110 EGLSTSGPPTISKGLCTSVT----LAASEGRNTSRPPTSSEEPSTSVPPTAS-------- 157

Query: 162 QIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNT--MPSGGNSVSSGSSVS 219
              +PS+ +PP P     T+ PP        +++ +   G +T  +P+ G     G+SV 
Sbjct: 158 --EVPSTSLPPTPGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGE--GPGTSVP 213

Query: 220 STSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATG 279
             + + L TS   + P    S + PP    G  T V   +      S P  P E    + 
Sbjct: 214 LAATEGLSTSVQ-ATPDEGPSTSVPPTATEGLSTPVPPTRDEGPSTSVPATPGEGPSTSV 272

Query: 280 TTSASDDLEALGTLSLGTTEEKAAAEAAVPRTIGAELMELVRRNTG 325
             +ASD      ++SL  T  K ++  +VP T    L   V+   G
Sbjct: 273 LPAASDG----QSISLVPTRGKGSS-TSVPPTATEGLSTSVQPTAG 313



 Score = 43.9 bits (102), Expect = 5e-04
 Identities = 38/146 (26%), Positives = 56/146 (38%), Gaps = 6/146 (4%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P + + P P     T+ PP + +    ++  + S G NT     +S    +SV  T+ + 
Sbjct: 100 PGTSVLPTPSEGLSTSGPPTISKGLCTSVTLAASEGRNTSRPPTSSEEPSTSVPPTASEV 159

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASD 285
             TS  P+ PG   S + PP    G  T+V          S    P E     GT+    
Sbjct: 160 PSTSLPPT-PGEGTSTSVPPTAYEGPSTSVVPTPDEGPSTSVLPTPGE---GPGTSVPLA 215

Query: 286 DLEALGTLSLGTTEEKAAAEAAVPRT 311
             E L T    T +E      +VP T
Sbjct: 216 ATEGLSTSVQATPDE--GPSTSVPPT 239



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 4/107 (3%)

Query: 168 SQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMP-SGGNSVSSGSSVSSTSLDTL 226
           S +P + + ++ + PP   +         +G G   ++P + G  +S+  SV  T+ + L
Sbjct: 283 SLVPTRGKGSSTSVPPTATEGLSTSVQPTAGEGSSTSVPPTPGGGLST--SVPPTATEEL 340

Query: 227 YTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
            TS  P+ PG   S +  P+P  G  T+V       S  S P  P E
Sbjct: 341 STSVPPT-PGEGPSTSVLPIPGEGLSTSVPPTASDGSDTSVPPTPGE 386



 Score = 34.7 bits (78), Expect = 0.32
 Identities = 36/131 (27%), Positives = 51/131 (38%), Gaps = 16/131 (12%)

Query: 167 SSQIPPQPRRAAPTT-PPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVS-----S 220
           S+ +PP       T+ PP P +      L   G G   ++P    + S GS  S      
Sbjct: 329 STSVPPTATEELSTSVPPTPGEGPSTSVLPIPGEGLSTSVPP---TASDGSDTSVPPTPG 385

Query: 221 TSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGT 280
               TL   ++P  PGSS  P P   P     ++ + V   PSK S   P      +   
Sbjct: 386 EGASTLVQPTAPDGPGSSVLPNPGEGPST-LFSSSASVDRNPSKCSLVLP------SPRV 438

Query: 281 TSASDDLEALG 291
           T AS D ++ G
Sbjct: 439 TKASVDSDSEG 449


>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
          Length = 620

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 20/50 (40%), Positives = 30/50 (60%), Gaps = 1/50 (2%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY +++ +P  LA    E + +L+ S  HWW   + R+G  GYVP +YL
Sbjct: 178 ALYDYQTNDPQELALRRNEEYCLLDSSEIHWW-RVQDRNGHEGYVPSSYL 226


>gi|158534059 formin binding protein 4 [Homo sapiens]
          Length = 1017

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 56/258 (21%), Positives = 98/258 (37%), Gaps = 22/258 (8%)

Query: 99  HRKETLSRRGPSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADG 158
           +R ETL+++        +   + +D +   ++      +C+  F  Q S  S   L    
Sbjct: 641 NRDETLAKQ-------TLKDKTGTDSNSTESSETSTGSLCKESFSGQVSSSSLMPLTPFW 693

Query: 159 GLYQ---------IPLPSSQIPPQPRRAAPTTPPPPVKRRDREAL-MASGSGGHNTMPSG 208
            L Q         +PL     PP P  + P  PPPP    D E   +     G    P+ 
Sbjct: 694 TLLQSNVPVLQPPLPLEMPPPPPPPPESPPPPPPPPPPAEDGEIQEVEMEDEGSEEPPAP 753

Query: 209 GNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAP 268
           G      + +  ++  T+ TS S  +   S S +   + R+ T  + + VQ   +  S+P
Sbjct: 754 G--TEEDTPLKPSAQTTVVTSQSSVDSTISSSSSTKGIKRKATEISTAVVQRSATIGSSP 811

Query: 269 EPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAA---EAAVPRTIGAELMELVRRNTG 325
              ++  +ATG  +A    +A G           AA     A   ++ +  + L      
Sbjct: 812 VLYSQSAIATGHQAAGIGNQATGIGHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAI 871

Query: 326 LSHELCRVAIGIIVGHIQ 343
           +S+  C V IG+    +Q
Sbjct: 872 MSYAECSVPIGVTAPSLQ 889



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 23/81 (28%), Positives = 34/81 (41%), Gaps = 10/81 (12%)

Query: 201 GHNTMPSGGNSVSSGSSVSSTSLDTLYT--SSSP--------SEPGSSCSPTPPPVPRRG 250
           GH T+P    +   G      SL + Y   +++P        S P    +P+  PV  RG
Sbjct: 836 GHQTIPVSLPAAGMGHQARGMSLQSNYLGLAAAPAIMSYAECSVPIGVTAPSLQPVQARG 895

Query: 251 THTTVSQVQPPPSKASAPEPP 271
              T + ++PPP     P PP
Sbjct: 896 AVPTATIIEPPPPPPPPPPPP 916


>gi|38683860 insulin receptor substrate 2 [Homo sapiens]
          Length = 1338

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 76/340 (22%), Positives = 120/340 (35%), Gaps = 52/340 (15%)

Query: 56   LQGLEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVA 115
            L+G+      ++ R+ +A + T   D  +Y L    V + L   R E  +  GPS ++ A
Sbjct: 795  LRGVPGCCYSSLPRSYKAPY-TCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASA 853

Query: 116  VMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIP-LPSSQIPPQP 174
                 T   H    +  +P+G    GF  Q          +  GL  +P +    +PP+P
Sbjct: 854  FGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEP 913

Query: 175  RR------------AAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTS 222
            +              A  +PP P        L+AS +   + + +   + S GS    TS
Sbjct: 914  KSPGEYINIDFGEPGARLSPPAP-------PLLASAASSSSLLSASSPASSLGSGTPGTS 966

Query: 223  LDTLYTS----------SSPSEP--------------------GSSCSPTPPPVPRRGTH 252
             D+   S          SSP  P                     SS  P  PP P     
Sbjct: 967  SDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPS 1026

Query: 253  TTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEEKAAAEAAV-PRT 311
            +++    PPP+       P    VAT     +    +  T   G   E A   AA  P+ 
Sbjct: 1027 SSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQP 1086

Query: 312  IGAELMELVRRNTGLSHELCRVAIGIIVGHIQASVPASSP 351
            I A       R    +  + R+++   V  ++A + AS P
Sbjct: 1087 IAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQP 1126



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 37/153 (24%), Positives = 52/153 (33%), Gaps = 12/153 (7%)

Query: 99   HRKETLSRRGPSAS----SVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHL 154
            HR   + R  P       S    +S+T+   +  + A  P     A  E      SSE  
Sbjct: 1130 HRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSE-- 1187

Query: 155  GADGGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSS 214
               GG+   P    + P  PR+  P    PP+  + R        G      SGG+ +  
Sbjct: 1188 ---GGVGVGPGGGDEPPTSPRQLQPA---PPLAPQGRPWTPGQPGGLVGCPGSGGSPMRR 1241

Query: 215  GSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 247
             +S    +           EPG    P PPP P
Sbjct: 1242 ETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPP 1274


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 39/130 (30%), Positives = 54/130 (41%), Gaps = 21/130 (16%)

Query: 174 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVS-STSLDTLYTSSSP 232
           P++    +  P   RR R+   +S S  +++  S  +S  SGS  S S S  + Y+S S 
Sbjct: 525 PKKKLGVSVSPSRARRRRKTSASSASASNSSRSSSRSSSYSGSGSSRSRSRSSSYSSYSS 584

Query: 233 SEP---------------GSSCSPTPPPVPRRGTHTTVSQVQPPPSKA-----SAPEPPA 272
                              SS SP+P P P R +  T  +  PPP KA       P PP 
Sbjct: 585 RSSRHSSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPP 644

Query: 273 EEEVATGTTS 282
               AT TT+
Sbjct: 645 APPQATKTTA 654



 Score = 35.0 bits (79), Expect = 0.24
 Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 15/126 (11%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P+P    P  PR A     P     R R  L  SGSG  ++  SG +S S   SVSS S 
Sbjct: 655 PVPEPTKPGDPREARRKERPARTPPR-RRTLSGSGSGSGSSY-SGSSSRSRSLSVSSVSS 712

Query: 224 DTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEP-PAEEEVATGTTS 282
            +  TSSS S                 +    + +  P S AS+  P PA+     G + 
Sbjct: 713 VSSATSSSSSAHSVD------------SEDMYADLASPVSSASSRSPAPAQTRKEKGKSK 760

Query: 283 ASDDLE 288
             D ++
Sbjct: 761 KEDGVK 766



 Score = 31.6 bits (70), Expect = 2.7
 Identities = 26/98 (26%), Positives = 34/98 (34%), Gaps = 10/98 (10%)

Query: 197 SGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCS------PTPPPVPRRG 250
           S   G  +     +S  S S   S    ++ T   P+ P           P PPP P + 
Sbjct: 590 SSFSGSRSRSRSFSSSPSPSPTPSPHRPSIRTKGEPAPPPGKAGEKSVKKPAPPPAPPQA 649

Query: 251 THTTVSQVQP----PPSKASAPEPPAEEEVATGTTSAS 284
           T TT    +P     P +A   E PA       T S S
Sbjct: 650 TKTTAPVPEPTKPGDPREARRKERPARTPPRRRTLSGS 687


>gi|148596974 TXK tyrosine kinase [Homo sapiens]
          Length = 527

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 22/51 (43%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 3   RALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           +ALY F   EP  LA    E +L+LE+ + HWW  AR R G  G +P  Y+
Sbjct: 88  KALYDFLPREPCNLALRRAEEYLILEKYNPHWW-KARDRLGNEGLIPSNYV 137


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 37/119 (31%), Positives = 48/119 (40%), Gaps = 21/119 (17%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P  Q PP P+      PPPP +   +  ++A G G     P  G++  + SS       T
Sbjct: 83  PPHQPPPHPQPHQQQQPPPPPQDSSKP-VVAQGPG---PAPGVGSAPPASSSAPPA---T 135

Query: 226 LYTSSSPSEPGSSCSPTPPPV-------------PRRGTHTTVSQV-QPPPSKASAPEP 270
             TS +P   G   +PTPPP              P  G  TT  Q   PPP  A+ P P
Sbjct: 136 PPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGP 194



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 25/86 (29%), Positives = 31/86 (36%), Gaps = 2/86 (2%)

Query: 189 RDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPR 248
           RDR      G GG +    GG         S      L  +  P  PG   S   PP+P 
Sbjct: 3   RDRFRSRGGGGGGFHRRGGGGGRGGLHDFRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPP 62

Query: 249 RGTHTTVSQVQPPPSKASAPEPPAEE 274
              H    Q QPPP +    +PP  +
Sbjct: 63  PPPHQ--QQQQPPPQQPPPQQPPPHQ 86


>gi|38202217 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY + S     L+F  GE   ++  +   WWLA    +G+TGY+P  Y+
Sbjct: 91  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 140


>gi|4885609 proto-oncogene tyrosine-protein kinase SRC [Homo
           sapiens]
          Length = 536

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 18/50 (36%), Positives = 27/50 (54%)

Query: 4   ALYAFRSAEPNALAFAAGETFLVLERSSAHWWLAARARSGETGYVPPAYL 53
           ALY + S     L+F  GE   ++  +   WWLA    +G+TGY+P  Y+
Sbjct: 91  ALYDYESRTETDLSFKKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYV 140


>gi|24586659 scavenger receptor class F, member 2 isoform 1 [Homo
           sapiens]
          Length = 870

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 50/208 (24%)

Query: 109 PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSS 168
           P+++  A+   ++SD    A++   P G   A   R+ + P+    G  GGL        
Sbjct: 598 PASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARAR-GEIGGL-------- 648

Query: 169 QIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYT 228
            + P P R  P  P P  K +     ++   G H+   +G                    
Sbjct: 649 SLSPSPERRKPPPPDPATKPK-----VSWIHGKHSAAAAG-------------------R 684

Query: 229 SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQ--PPPSKASAPEPPAEEEVATGTTSASDD 286
           + SP  PGS  +P+P    R  +  +   V+   P ++   P PP   E AT   + S  
Sbjct: 685 APSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPS-- 742

Query: 287 LEALGTLSLGTTEEKAAAEAAVPRTIGA 314
                         +A A AA PR +GA
Sbjct: 743 ------------PPRARARAA-PRPLGA 757



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 12/122 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSS-------GSSV 218
           P+ + P  P  A     P P + R R A    G+ G    P+     +S       G + 
Sbjct: 724 PTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTR 783

Query: 219 SSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
           S    +    +  P E      P PP   +R          PP ++   PE  A +  A 
Sbjct: 784 SLGRAEVALGAQGPRE-----KPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAP 838

Query: 279 GT 280
            T
Sbjct: 839 ET 840


>gi|33598937 scavenger receptor class F, member 2 isoform 2 [Homo
           sapiens]
          Length = 865

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 49/208 (23%), Positives = 77/208 (37%), Gaps = 50/208 (24%)

Query: 109 PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSS 168
           P+++  A+   ++SD    A++   P G   A   R+ + P+    G  GGL        
Sbjct: 593 PASAEEAIPLPASSDSERSASSVEGPGGALYARVARREARPARAR-GEIGGL-------- 643

Query: 169 QIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYT 228
            + P P R  P  P P  K +     ++   G H+   +G                    
Sbjct: 644 SLSPSPERRKPPPPDPATKPK-----VSWIHGKHSAAAAG-------------------R 679

Query: 229 SSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQ--PPPSKASAPEPPAEEEVATGTTSASDD 286
           + SP  PGS  +P+P    R  +  +   V+   P ++   P PP   E AT   + S  
Sbjct: 680 APSPPPPGSEAAPSPSKRKRTPSDKSAHTVEHGSPRTRDPTPRPPGLPEEATALAAPS-- 737

Query: 287 LEALGTLSLGTTEEKAAAEAAVPRTIGA 314
                         +A A AA PR +GA
Sbjct: 738 ------------PPRARARAA-PRPLGA 752



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 28/122 (22%), Positives = 41/122 (33%), Gaps = 12/122 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSS-------GSSV 218
           P+ + P  P  A     P P + R R A    G+ G    P+     +S       G + 
Sbjct: 719 PTPRPPGLPEEATALAAPSPPRARARAAPRPLGAHGRRRSPAKRAEAASMLAADVRGKTR 778

Query: 219 SSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
           S    +    +  P E      P PP   +R          PP ++   PE  A +  A 
Sbjct: 779 SLGRAEVALGAQGPRE-----KPAPPQKAKRSVPPASPARAPPATETPGPEKAATDLPAP 833

Query: 279 GT 280
            T
Sbjct: 834 ET 835


>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
          Length = 2365

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 180 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 239
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 235 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 291

Query: 240 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 288
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 292 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 342



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 30/141 (21%), Positives = 48/141 (34%), Gaps = 16/141 (11%)

Query: 142 FERQHSLPSSEHLGAD-----------GGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRD 190
           +++Q   P  +HL +                Q   P  Q+P  P+       P P ++  
Sbjct: 126 YKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSK 185

Query: 191 REALMASGSGGHNTMPSGGNS---VSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 247
            +A M S   G     S   S      GS+ ++      + +   S+P +  SP PPP  
Sbjct: 186 AQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVT--SPPPPPSS 243

Query: 248 RRGTHTTVSQVQPPPSKASAP 268
                   S    P    +AP
Sbjct: 244 HEKEPLASSASSHPGMSDNAP 264


>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
          Length = 2432

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 180 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 239
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 299 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 355

Query: 240 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 288
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 356 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 406



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 30/141 (21%), Positives = 48/141 (34%), Gaps = 16/141 (11%)

Query: 142 FERQHSLPSSEHLGAD-----------GGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRD 190
           +++Q   P  +HL +                Q   P  Q+P  P+       P P ++  
Sbjct: 190 YKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSK 249

Query: 191 REALMASGSGGHNTMPSGGNS---VSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 247
            +A M S   G     S   S      GS+ ++      + +   S+P +  SP PPP  
Sbjct: 250 AQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVT--SPPPPPSS 307

Query: 248 RRGTHTTVSQVQPPPSKASAP 268
                   S    P    +AP
Sbjct: 308 HEKEPLASSASSHPGMSDNAP 328


>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
          Length = 2429

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 33/111 (29%), Positives = 50/111 (45%), Gaps = 5/111 (4%)

Query: 180 TTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSC 239
           T+PPPP    ++E L +S S       +   S+ SGSS + T+     TSS+  +PG++ 
Sbjct: 299 TSPPPPPSSHEKEPLASSASSHPGMSDNAPASLESGSSSTPTNCS---TSSAIPQPGAAT 355

Query: 240 SPTPPPVPRRGTHTTVS--QVQPPPSKASAPEPPAEEEVATGTTSASDDLE 288
            P            TVS   V+PP  +A  P P A +       S  + L+
Sbjct: 356 KPWRSKSLSVKHSATVSMLSVKPPGPEAPRPTPEAMKPAPNNQKSMLEKLK 406



 Score = 30.8 bits (68), Expect = 4.6
 Identities = 30/141 (21%), Positives = 48/141 (34%), Gaps = 16/141 (11%)

Query: 142 FERQHSLPSSEHLGAD-----------GGLYQIPLPSSQIPPQPRRAAPTTPPPPVKRRD 190
           +++Q   P  +HL +                Q   P  Q+P  P+       P P ++  
Sbjct: 190 YKQQQQQPQKQHLSSPLPPAVSQVAGAPSQCQAGTPQQQVPVTPQAPCQPHQPAPHQQSK 249

Query: 191 REALMASGSGGHNTMPSGGNS---VSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVP 247
            +A M S   G     S   S      GS+ ++      + +   S+P +  SP PPP  
Sbjct: 250 AQAEMQSRLPGPTARVSAAGSEAKTRGGSTTANNRRSQSFNNYDKSKPVT--SPPPPPSS 307

Query: 248 RRGTHTTVSQVQPPPSKASAP 268
                   S    P    +AP
Sbjct: 308 HEKEPLASSASSHPGMSDNAP 328


>gi|122939147 Rho GTPase activating protein 9 isoform 1 [Homo
           sapiens]
          Length = 731

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 77/308 (25%), Positives = 115/308 (37%), Gaps = 63/308 (20%)

Query: 4   ALYAFR--SAEPNALAFAAGETFLVLERSSAHWWLAARARSGETG---YVPPAYLRRLQG 58
           ALYAF    A+   ++ A G+ FL+L ++++ WWLA R  +  T    +VP AY+     
Sbjct: 29  ALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYM----- 83

Query: 59  LEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVA--- 115
                   I+ +I +   T +  G    L   G   KL H   E LS+  PS +  +   
Sbjct: 84  --------IEESIPSQSPTTVIPG--QLLWTPG--PKLFHGSLEELSQALPSRAQASSEQ 131

Query: 116 ------VMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQ 169
                  M  S S  +L  +  +            Q  LPS       G     P P   
Sbjct: 132 PPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG-----PQPLMS 186

Query: 170 IPP-----QPRRAAPTTPPPP-----VKRRDR-EALMASGSG---------GHNTMPSGG 209
            PP        R  P +PPP      ++R D  E  +   SG         G  +     
Sbjct: 187 EPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPR 246

Query: 210 NSVSSGSSVSSTSLDTLYTSSSPSEPGS----SCSPTPPPVPRRGT---HTTVSQVQPPP 262
            S S  +  S     TL  ++   +P +    S + TP P+  +G+       SQ+ PP 
Sbjct: 247 RSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPA 306

Query: 263 SKASAPEP 270
            +A  P P
Sbjct: 307 LQAPRPLP 314


>gi|122939151 Rho GTPase activating protein 9 isoform 2 [Homo
           sapiens]
          Length = 640

 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 77/308 (25%), Positives = 115/308 (37%), Gaps = 63/308 (20%)

Query: 4   ALYAFR--SAEPNALAFAAGETFLVLERSSAHWWLAARARSGETG---YVPPAYLRRLQG 58
           ALYAF    A+   ++ A G+ FL+L ++++ WWLA R  +  T    +VP AY+     
Sbjct: 29  ALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYM----- 83

Query: 59  LEQDVLQAIDRAIEAVHNTAMRDGGKYSLEQRGVLQKLIHHRKETLSRRGPSASSVA--- 115
                   I+ +I +   T +  G    L   G   KL H   E LS+  PS +  +   
Sbjct: 84  --------IEESIPSQSPTTVIPG--QLLWTPG--PKLFHGSLEELSQALPSRAQASSEQ 131

Query: 116 ------VMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLYQIPLPSSQ 169
                  M  S S  +L  +  +            Q  LPS       G     P P   
Sbjct: 132 PPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG-----PQPLMS 186

Query: 170 IPP-----QPRRAAPTTPPPP-----VKRRDR-EALMASGSG---------GHNTMPSGG 209
            PP        R  P +PPP      ++R D  E  +   SG         G  +     
Sbjct: 187 EPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPR 246

Query: 210 NSVSSGSSVSSTSLDTLYTSSSPSEPGS----SCSPTPPPVPRRGT---HTTVSQVQPPP 262
            S S  +  S     TL  ++   +P +    S + TP P+  +G+       SQ+ PP 
Sbjct: 247 RSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPA 306

Query: 263 SKASAPEP 270
            +A  P P
Sbjct: 307 LQAPRPLP 314


>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
          Length = 1270

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      ++ S+ ++T    
Sbjct: 345 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 404

Query: 226 LYTSSS----PSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+ S    P EP  + +  P P  P+    TT  +  P   K  AP  P E    T
Sbjct: 405 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/120 (25%), Positives = 41/120 (34%), Gaps = 7/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      +   +  +T    
Sbjct: 431 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 490

Query: 226 LYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+     P +   P P       P  P   T TT  +  P   KA+AP  P E    T
Sbjct: 491 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 550



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 6/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P + APTTP  P      E    +      T P      +  ++  +T  + 
Sbjct: 487 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 546

Query: 226 LYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASA---PEPPAEEEVATGTT 281
             T  +P EP  +    P P  P+    TT     P   K  A   P+ PA +E+A  TT
Sbjct: 547 APT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 604



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 4/119 (3%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P P++   P P+  APTT   P      +    +  G   T P      +      +T  
Sbjct: 586 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 645

Query: 224 DTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
            T  T+     P +   P P    P   +  T TT  +  P   K +AP  P E    T
Sbjct: 646 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 704



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 36/162 (22%), Positives = 51/162 (31%), Gaps = 16/162 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P    PTTP  P     + A   +      T P      +      +T  +T
Sbjct: 511 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 570

Query: 226 LYTSSSPSEPGSSCSPTP------------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
             T+   + P +   P P            P   +  T TT  +  P   K +AP  P E
Sbjct: 571 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 630

Query: 274 EEVATGTTSASDDLEALGTLSL----GTTEEKAAAEAAVPRT 311
               T    A    +     +L     TT +K A +   P T
Sbjct: 631 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 672



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 14/122 (11%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  +   P  P+  APTTP  P     +E    +      T P            + T+ 
Sbjct: 288 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---------KEPAPTTK 338

Query: 224 DTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTS 282
           +   T  +P EP  +    P P  P+    TT    +P P+    P P   +E A  TT 
Sbjct: 339 EPAPT--TPKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPAPTTTK 394

Query: 283 AS 284
           ++
Sbjct: 395 SA 396



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 35/143 (24%), Positives = 48/143 (33%), Gaps = 19/143 (13%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTM--------PSGGNSVSSGSS 217
           P    P  P+  APTTP  P     +E    +  G   T         P          +
Sbjct: 543 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 602

Query: 218 VSSTSLDTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAP---EP 270
            +     T     +P+ P  +   TP    P  P+    TT     P   K  AP   + 
Sbjct: 603 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 662

Query: 271 PAEEEVAT----GTTSASDDLEA 289
           PA +E+A     G TS + D  A
Sbjct: 663 PAPKELAPTTTKGPTSTTSDKPA 685



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/117 (22%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  + +  P   ++APTTP  P     +E    +      T P      +      +T  
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456

Query: 224 DTLYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
           +   T++    P +   P P       P  P++ T TT  ++ P   +  AP  P E
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 513



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/113 (22%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P+  A TTP  P     + A          T  S   +    +  ++     
Sbjct: 213 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 270

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
               ++P EP  + +  P P   +   TT  +  P   K  AP  P E    T
Sbjct: 271 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 321



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 32/148 (21%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P                    P   + VS+ ++    +  T
Sbjct: 697 PKEPAPTTPKKPAPTTPETP--------------------PPTTSEVSTPTTTKEPT--T 734

Query: 226 LYTSSSPSEPGSSCSPTP------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT- 278
           ++ S   S P  S  PTP      P  P   T  T +  +P  +  +A +   E ++ T 
Sbjct: 735 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-TTAKDKTTERDLRTT 793

Query: 279 --GTTSASDDLEALGTLSLGTTEEKAAA 304
              TT+A    +   T +  TTE K  A
Sbjct: 794 PETTTAAPKMTKETATTTEKTTESKITA 821



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 26/119 (21%), Positives = 38/119 (31%), Gaps = 7/119 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P   +  APTTP  P     +E    +      T P      +      +T  + 
Sbjct: 259 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEPAPTTPKKPAPTTPKEP 317

Query: 226 LYTS------SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+      ++P EP  +     P  P+    T   +  P   K  AP  P E    T
Sbjct: 318 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 376



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/120 (20%), Positives = 39/120 (32%), Gaps = 3/120 (2%)

Query: 164 PLPSSQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSST 221
           P    +  P   ++APTTP  P P   ++             T      +  S  +    
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 300

Query: 222 SLDTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGT 280
              T     +P+ P      TP  P P        +  +P P+    P P A ++ A  T
Sbjct: 301 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 360



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/119 (21%), Positives = 42/119 (35%), Gaps = 13/119 (10%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P+S++  +P   A TT   P     +E           T P    S +      +T    
Sbjct: 189 PTSKVLAKPTPKAETTTKGPALTTPKEPTP--------TTPKEPASTTPKEPTPTTIKSA 240

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSAS 284
             T   P+   +  +PT P  P        +  +P P+    P P   +E A  TT ++
Sbjct: 241 PTTPKEPAPTTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 294


>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
          Length = 1311

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      ++ S+ ++T    
Sbjct: 386 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 445

Query: 226 LYTSSS----PSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+ S    P EP  + +  P P  P+    TT  +  P   K  AP  P E    T
Sbjct: 446 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/120 (25%), Positives = 41/120 (34%), Gaps = 7/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      +   +  +T    
Sbjct: 472 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 531

Query: 226 LYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+     P +   P P       P  P   T TT  +  P   KA+AP  P E    T
Sbjct: 532 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 591



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 6/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P + APTTP  P      E    +      T P      +  ++  +T  + 
Sbjct: 528 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 587

Query: 226 LYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASA---PEPPAEEEVATGTT 281
             T  +P EP  +    P P  P+    TT     P   K  A   P+ PA +E+A  TT
Sbjct: 588 APT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 645



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 4/119 (3%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P P++   P P+  APTT   P      +    +  G   T P      +      +T  
Sbjct: 627 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 686

Query: 224 DTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
            T  T+     P +   P P    P   +  T TT  +  P   K +AP  P E    T
Sbjct: 687 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 745



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 36/162 (22%), Positives = 51/162 (31%), Gaps = 16/162 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P    PTTP  P     + A   +      T P      +      +T  +T
Sbjct: 552 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 611

Query: 226 LYTSSSPSEPGSSCSPTP------------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
             T+   + P +   P P            P   +  T TT  +  P   K +AP  P E
Sbjct: 612 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 671

Query: 274 EEVATGTTSASDDLEALGTLSL----GTTEEKAAAEAAVPRT 311
               T    A    +     +L     TT +K A +   P T
Sbjct: 672 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 713



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 14/122 (11%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  +   P  P+  APTTP  P     +E    +      T P            + T+ 
Sbjct: 329 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---------KEPAPTTK 379

Query: 224 DTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTS 282
           +   T  +P EP  +    P P  P+    TT    +P P+    P P   +E A  TT 
Sbjct: 380 EPAPT--TPKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPAPTTTK 435

Query: 283 AS 284
           ++
Sbjct: 436 SA 437



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 35/143 (24%), Positives = 48/143 (33%), Gaps = 19/143 (13%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTM--------PSGGNSVSSGSS 217
           P    P  P+  APTTP  P     +E    +  G   T         P          +
Sbjct: 584 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 643

Query: 218 VSSTSLDTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAP---EP 270
            +     T     +P+ P  +   TP    P  P+    TT     P   K  AP   + 
Sbjct: 644 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 703

Query: 271 PAEEEVAT----GTTSASDDLEA 289
           PA +E+A     G TS + D  A
Sbjct: 704 PAPKELAPTTTKGPTSTTSDKPA 726



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/117 (22%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  + +  P   ++APTTP  P     +E    +      T P      +      +T  
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497

Query: 224 DTLYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
           +   T++    P +   P P       P  P++ T TT  ++ P   +  AP  P E
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 554



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/113 (22%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P+  A TTP  P     + A          T  S   +    +  ++     
Sbjct: 254 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 311

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
               ++P EP  + +  P P   +   TT  +  P   K  AP  P E    T
Sbjct: 312 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 362



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 32/148 (21%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P                    P   + VS+ ++    +  T
Sbjct: 738 PKEPAPTTPKKPAPTTPETP--------------------PPTTSEVSTPTTTKEPT--T 775

Query: 226 LYTSSSPSEPGSSCSPTP------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT- 278
           ++ S   S P  S  PTP      P  P   T  T +  +P  +  +A +   E ++ T 
Sbjct: 776 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-TTAKDKTTERDLRTT 834

Query: 279 --GTTSASDDLEALGTLSLGTTEEKAAA 304
              TT+A    +   T +  TTE K  A
Sbjct: 835 PETTTAAPKMTKETATTTEKTTESKITA 862



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 26/119 (21%), Positives = 38/119 (31%), Gaps = 7/119 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P   +  APTTP  P     +E    +      T P      +      +T  + 
Sbjct: 300 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEPAPTTPKKPAPTTPKEP 358

Query: 226 LYTS------SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+      ++P EP  +     P  P+    T   +  P   K  AP  P E    T
Sbjct: 359 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 417



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/120 (20%), Positives = 39/120 (32%), Gaps = 3/120 (2%)

Query: 164 PLPSSQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSST 221
           P    +  P   ++APTTP  P P   ++             T      +  S  +    
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 341

Query: 222 SLDTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGT 280
              T     +P+ P      TP  P P        +  +P P+    P P A ++ A  T
Sbjct: 342 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 401



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/119 (21%), Positives = 42/119 (35%), Gaps = 13/119 (10%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P+S++  +P   A TT   P     +E           T P    S +      +T    
Sbjct: 230 PTSKVLAKPTPKAETTTKGPALTTPKEPTP--------TTPKEPASTTPKEPTPTTIKSA 281

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSAS 284
             T   P+   +  +PT P  P        +  +P P+    P P   +E A  TT ++
Sbjct: 282 PTTPKEPAPTTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 335


>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
          Length = 1363

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      ++ S+ ++T    
Sbjct: 438 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 497

Query: 226 LYTSSS----PSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+ S    P EP  + +  P P  P+    TT  +  P   K  AP  P E    T
Sbjct: 498 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/120 (25%), Positives = 41/120 (34%), Gaps = 7/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      +   +  +T    
Sbjct: 524 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 583

Query: 226 LYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+     P +   P P       P  P   T TT  +  P   KA+AP  P E    T
Sbjct: 584 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 643



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 6/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P + APTTP  P      E    +      T P      +  ++  +T  + 
Sbjct: 580 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 639

Query: 226 LYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASA---PEPPAEEEVATGTT 281
             T  +P EP  +    P P  P+    TT     P   K  A   P+ PA +E+A  TT
Sbjct: 640 APT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 697



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 4/119 (3%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P P++   P P+  APTT   P      +    +  G   T P      +      +T  
Sbjct: 679 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 738

Query: 224 DTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
            T  T+     P +   P P    P   +  T TT  +  P   K +AP  P E    T
Sbjct: 739 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 797



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 36/162 (22%), Positives = 51/162 (31%), Gaps = 16/162 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P    PTTP  P     + A   +      T P      +      +T  +T
Sbjct: 604 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 663

Query: 226 LYTSSSPSEPGSSCSPTP------------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
             T+   + P +   P P            P   +  T TT  +  P   K +AP  P E
Sbjct: 664 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 723

Query: 274 EEVATGTTSASDDLEALGTLSL----GTTEEKAAAEAAVPRT 311
               T    A    +     +L     TT +K A +   P T
Sbjct: 724 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 765



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 14/122 (11%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  +   P  P+  APTTP  P     +E    +      T P            + T+ 
Sbjct: 381 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---------KEPAPTTK 431

Query: 224 DTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTS 282
           +   T  +P EP  +    P P  P+    TT    +P P+    P P   +E A  TT 
Sbjct: 432 EPAPT--TPKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPAPTTTK 487

Query: 283 AS 284
           ++
Sbjct: 488 SA 489



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 35/143 (24%), Positives = 48/143 (33%), Gaps = 19/143 (13%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTM--------PSGGNSVSSGSS 217
           P    P  P+  APTTP  P     +E    +  G   T         P          +
Sbjct: 636 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 695

Query: 218 VSSTSLDTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAP---EP 270
            +     T     +P+ P  +   TP    P  P+    TT     P   K  AP   + 
Sbjct: 696 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 755

Query: 271 PAEEEVAT----GTTSASDDLEA 289
           PA +E+A     G TS + D  A
Sbjct: 756 PAPKELAPTTTKGPTSTTSDKPA 778



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/117 (22%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  + +  P   ++APTTP  P     +E    +      T P      +      +T  
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549

Query: 224 DTLYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
           +   T++    P +   P P       P  P++ T TT  ++ P   +  AP  P E
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 606



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/113 (22%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P+  A TTP  P     + A          T  S   +    +  ++     
Sbjct: 306 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 363

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
               ++P EP  + +  P P   +   TT  +  P   K  AP  P E    T
Sbjct: 364 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 414



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 32/148 (21%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P                    P   + VS+ ++    +  T
Sbjct: 790 PKEPAPTTPKKPAPTTPETP--------------------PPTTSEVSTPTTTKEPT--T 827

Query: 226 LYTSSSPSEPGSSCSPTP------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT- 278
           ++ S   S P  S  PTP      P  P   T  T +  +P  +  +A +   E ++ T 
Sbjct: 828 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-TTAKDKTTERDLRTT 886

Query: 279 --GTTSASDDLEALGTLSLGTTEEKAAA 304
              TT+A    +   T +  TTE K  A
Sbjct: 887 PETTTAAPKMTKETATTTEKTTESKITA 914



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 26/119 (21%), Positives = 38/119 (31%), Gaps = 7/119 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P   +  APTTP  P     +E    +      T P      +      +T  + 
Sbjct: 352 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEPAPTTPKKPAPTTPKEP 410

Query: 226 LYTS------SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+      ++P EP  +     P  P+    T   +  P   K  AP  P E    T
Sbjct: 411 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 469



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/120 (20%), Positives = 39/120 (32%), Gaps = 3/120 (2%)

Query: 164 PLPSSQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSST 221
           P    +  P   ++APTTP  P P   ++             T      +  S  +    
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 393

Query: 222 SLDTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGT 280
              T     +P+ P      TP  P P        +  +P P+    P P A ++ A  T
Sbjct: 394 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 453



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/119 (21%), Positives = 42/119 (35%), Gaps = 13/119 (10%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P+S++  +P   A TT   P     +E           T P    S +      +T    
Sbjct: 282 PTSKVLAKPTPKAETTTKGPALTTPKEPTP--------TTPKEPASTTPKEPTPTTIKSA 333

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSAS 284
             T   P+   +  +PT P  P        +  +P P+    P P   +E A  TT ++
Sbjct: 334 PTTPKEPAPTTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 387


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/110 (28%), Positives = 38/110 (34%), Gaps = 9/110 (8%)

Query: 171 PPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVS--------SGSSVSSTS 222
           PP P R  P  PPPP          A G G     PS   + +           +V    
Sbjct: 279 PPPPSRGGPPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPP 338

Query: 223 LDTLYTSSSPSEPGSSCSPTPPPVPR-RGTHTTVSQVQPPPSKASAPEPP 271
            + +Y    P+ P S+ S  PPP P   G         PPP     P PP
Sbjct: 339 PNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPPPPPPPPGPPPP 388


>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
          Length = 1404

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 31/118 (26%), Positives = 45/118 (38%), Gaps = 5/118 (4%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      ++ S+ ++T    
Sbjct: 479 PKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPA 538

Query: 226 LYTSSS----PSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+ S    P EP  + +  P P  P+    TT  +  P   K  AP  P E    T
Sbjct: 539 PTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 30/120 (25%), Positives = 41/120 (34%), Gaps = 7/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P     +E    +      T P      +   +  +T    
Sbjct: 565 PKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKL 624

Query: 226 LYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+     P +   P P       P  P   T TT  +  P   KA+AP  P E    T
Sbjct: 625 TPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTT 684



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 32/120 (26%), Positives = 45/120 (37%), Gaps = 6/120 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P + APTTP  P      E    +      T P      +  ++  +T  + 
Sbjct: 621 PKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEP 680

Query: 226 LYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASA---PEPPAEEEVATGTT 281
             T  +P EP  +    P P  P+    TT     P   K  A   P+ PA +E+A  TT
Sbjct: 681 APT--TPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTT 738



 Score = 37.7 bits (86), Expect = 0.038
 Identities = 29/119 (24%), Positives = 41/119 (34%), Gaps = 4/119 (3%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P P++   P P+  APTT   P      +    +  G   T P      +      +T  
Sbjct: 720 PAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPK 779

Query: 224 DTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
            T  T+     P +   P P    P   +  T TT  +  P   K +AP  P E    T
Sbjct: 780 GTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTPKETAPTTPKEPAPTT 838



 Score = 37.4 bits (85), Expect = 0.049
 Identities = 36/162 (22%), Positives = 51/162 (31%), Gaps = 16/162 (9%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P    PTTP  P     + A   +      T P      +      +T  +T
Sbjct: 645 PEELAPTTPEEPTPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKET 704

Query: 226 LYTSSSPSEPGSSCSPTP------------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
             T+   + P +   P P            P   +  T TT  +  P   K +AP  P E
Sbjct: 705 APTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTPKE 764

Query: 274 EEVATGTTSASDDLEALGTLSL----GTTEEKAAAEAAVPRT 311
               T    A    +     +L     TT +K A +   P T
Sbjct: 765 PAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT 806



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 30/122 (24%), Positives = 45/122 (36%), Gaps = 14/122 (11%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  +   P  P+  APTTP  P     +E    +      T P            + T+ 
Sbjct: 422 PTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTP---------KEPAPTTK 472

Query: 224 DTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTS 282
           +   T  +P EP  +    P P  P+    TT    +P P+    P P   +E A  TT 
Sbjct: 473 EPAPT--TPKEPAPTAPKKPAPTTPKEPAPTTPK--EPAPTTTKEPSPTTPKEPAPTTTK 528

Query: 283 AS 284
           ++
Sbjct: 529 SA 530



 Score = 37.0 bits (84), Expect = 0.064
 Identities = 35/143 (24%), Positives = 48/143 (33%), Gaps = 19/143 (13%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTM--------PSGGNSVSSGSS 217
           P    P  P+  APTTP  P     +E    +  G   T         P          +
Sbjct: 677 PKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPT 736

Query: 218 VSSTSLDTLYTSSSPSEPGSSCSPTP----PPVPRRGTHTTVSQVQPPPSKASAP---EP 270
            +     T     +P+ P  +   TP    P  P+    TT     P   K  AP   + 
Sbjct: 737 TTKEPTSTTCDKPAPTTPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKK 796

Query: 271 PAEEEVAT----GTTSASDDLEA 289
           PA +E+A     G TS + D  A
Sbjct: 797 PAPKELAPTTTKGPTSTTSDKPA 819



 Score = 36.2 bits (82), Expect = 0.11
 Identities = 26/117 (22%), Positives = 43/117 (36%), Gaps = 7/117 (5%)

Query: 164 PLPSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSL 223
           P  + +  P   ++APTTP  P     +E    +      T P      +      +T  
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590

Query: 224 DTLYTSSSPSEPGSSCSPTP-------PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
           +   T++    P +   P P       P  P++ T TT  ++ P   +  AP  P E
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEE 647



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 25/113 (22%), Positives = 37/113 (32%), Gaps = 4/113 (3%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P+  A TTP  P     + A          T  S   +    +  ++     
Sbjct: 347 PKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEP-- 404

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
               ++P EP  + +  P P   +   TT  +  P   K  AP  P E    T
Sbjct: 405 --APTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTT 455



 Score = 34.3 bits (77), Expect = 0.42
 Identities = 37/148 (25%), Positives = 56/148 (37%), Gaps = 32/148 (21%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P  P++ APTTP  P                    P   + VS+ ++    +  T
Sbjct: 831 PKEPAPTTPKKPAPTTPETP--------------------PPTTSEVSTPTTTKEPT--T 868

Query: 226 LYTSSSPSEPGSSCSPTP------PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT- 278
           ++ S   S P  S  PTP      P  P   T  T +  +P  +  +A +   E ++ T 
Sbjct: 869 IHKSPDESTPELSAEPTPKALENSPKEPGVPTTKTPAATKPEMT-TTAKDKTTERDLRTT 927

Query: 279 --GTTSASDDLEALGTLSLGTTEEKAAA 304
              TT+A    +   T +  TTE K  A
Sbjct: 928 PETTTAAPKMTKETATTTEKTTESKITA 955



 Score = 33.1 bits (74), Expect = 0.93
 Identities = 26/119 (21%), Positives = 38/119 (31%), Gaps = 7/119 (5%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P    P   +  APTTP  P     +E    +      T P      +      +T  + 
Sbjct: 393 PKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTT-PKEPAPTTPKKPAPTTPKEP 451

Query: 226 LYTS------SSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVAT 278
             T+      ++P EP  +     P  P+    T   +  P   K  AP  P E    T
Sbjct: 452 APTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTT 510



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 25/120 (20%), Positives = 39/120 (32%), Gaps = 3/120 (2%)

Query: 164 PLPSSQIPPQPRRAAPTTP--PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSST 221
           P    +  P   ++APTTP  P P   ++             T      +  S  +    
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKE 434

Query: 222 SLDTLYTSSSPSEPGSSCSPTP-PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGT 280
              T     +P+ P      TP  P P        +  +P P+    P P A ++ A  T
Sbjct: 435 PAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTT 494



 Score = 30.0 bits (66), Expect = 7.9
 Identities = 26/119 (21%), Positives = 42/119 (35%), Gaps = 13/119 (10%)

Query: 166 PSSQIPPQPRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDT 225
           P+S++  +P   A TT   P     +E           T P    S +      +T    
Sbjct: 323 PTSKVLAKPTPKAETTTKGPALTTPKEPTP--------TTPKEPASTTPKEPTPTTIKSA 374

Query: 226 LYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSAS 284
             T   P+   +  +PT P  P        +  +P P+    P P   +E A  TT ++
Sbjct: 375 PTTPKEPAPTTTKSAPTTPKEP-----APTTTKEPAPTTPKEPAPTTTKEPAPTTTKSA 428


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 35/141 (24%), Positives = 54/141 (38%), Gaps = 7/141 (4%)

Query: 174 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPS 233
           PR A    P PP +   +    AS        P+     S+G  +   +  +L +S++P 
Sbjct: 190 PRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPL 249

Query: 234 EPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTL 293
              +   P+    PR   H +    QP P    A  PP   +V      A+  L  L + 
Sbjct: 250 SSPARSGPSARGTPRAPAHPS----QPKPKGLQALRPP---QVTPPRKDAAPALGPLSSS 302

Query: 294 SLGTTEEKAAAEAAVPRTIGA 314
            L T    AA ++  P T+ A
Sbjct: 303 PLATPSPSAALQSQAPPTLPA 323



 Score = 35.8 bits (81), Expect = 0.14
 Identities = 28/111 (25%), Positives = 42/111 (37%), Gaps = 16/111 (14%)

Query: 174 PRRAAPTTPPPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSSVSSTSLDTLYTSSSPS 233
           PR      PPPPV       L A+G+ G   +      +   +   S         + P+
Sbjct: 27  PRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESA------PRAGPT 80

Query: 234 EPGSSCSPTP---PPVPRRGTHTTVSQVQPPPSKASAPEPPAEEEVATGTT 281
               + S  P   PP   RG        + PP+K ++P P +    A+GTT
Sbjct: 81  RSAGTSSRNPASRPPASGRGE-------RAPPAKNTSPGPVSSPGRASGTT 124



 Score = 32.3 bits (72), Expect = 1.6
 Identities = 54/225 (24%), Positives = 83/225 (36%), Gaps = 35/225 (15%)

Query: 109 PSASSVAVMTSSTSDHHLDAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY-QIPLPS 167
           P A+      ++ + H L A  +  P+   +A F    S P S            +  P 
Sbjct: 419 PLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPP 478

Query: 168 SQIPPQPRRAAPTTP--------PPPVK-------RRDREALMASGSGGHNTMPS----- 207
            Q+PP P  + P +P        PPP+        +   +A  A  +     +PS     
Sbjct: 479 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASF 538

Query: 208 -GGNSVSSGSSVSSTSLDTLYTSSSP--SEPGSSCSPTPPP-----VPRR----GTHTTV 255
            G    S  +S+  + L T    + P  + P     P+PP       PRR    G  T+V
Sbjct: 539 PGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSV 598

Query: 256 SQVQPPPSKASAPEPPAEEEVATGTTSASDDLEALGTLSLGTTEE 300
           S   P  + A AP PP     +  +T +  DL    + +  T EE
Sbjct: 599 S--GPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEE 641



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 33/150 (22%), Positives = 49/150 (32%), Gaps = 28/150 (18%)

Query: 149 PSSEHLGADGGLYQIPLPSSQIPPQPRRAAPTT-------PP--------PPVKRRDREA 193
           P +E  G  GG     +P S     P R+A T+       PP        PP K      
Sbjct: 57  PLAERAGGIGGA---TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGP 113

Query: 194 LMASGSGGHNTMP----------SGGNSVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTP 243
           + + G     T P          S   +V+ G +  +     L   +     G +     
Sbjct: 114 VSSPGRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPS 173

Query: 244 PPVPRRGTHTTVSQVQPPPSKASAPEPPAE 273
           P + RR          P P+ ++ P PP E
Sbjct: 174 PAMARRSRAAGTEVGLPRPAPSARPRPPTE 203



 Score = 31.2 bits (69), Expect = 3.5
 Identities = 47/199 (23%), Positives = 69/199 (34%), Gaps = 32/199 (16%)

Query: 105 SRRGPSASSVAVMTSSTSDHHL---DAAAARQPNGVCRAGFERQHSLPSSEHLGADGGLY 161
           +R  P         SS S+H       AA R+P+     G +R    P+S  L +     
Sbjct: 196 ARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSA--GGGLQR----PASRSLSSSATPL 249

Query: 162 QIPLPSS-------QIPPQPRRAAP----TTPPPPVKRRDREALMASGSGGHNTMPSGGN 210
             P  S        + P  P +  P       PP V    ++A  A G    + + +   
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSP 309

Query: 211 SVSSGSSVSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKASAPEP 270
           S +  S    T   T ++SS   +  +   P  PP P             PPS  + P P
Sbjct: 310 SAALQSQAPPTLPATPHSSSLTCQLATPL-PLAPPSP-----------SAPPSLQTLPSP 357

Query: 271 PAEEEVATGTTSASDDLEA 289
           PA       T+  S  L+A
Sbjct: 358 PATPPSQATTSLGSPTLQA 376



 Score = 30.4 bits (67), Expect = 6.0
 Identities = 31/126 (24%), Positives = 42/126 (33%), Gaps = 10/126 (7%)

Query: 163 IPLPSSQIPPQPRRAAPTTP-----PPPVKRRDREALMASGSGGHNTMPSGGNSVSSGSS 217
           + LP  Q PP P  + P +P     P          L A  S   +       S  +   
Sbjct: 400 LALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPP 459

Query: 218 VSSTSLDTLYTSSSPSEPGSSCSPTPPPVPRRGTHTTVSQVQPPPSKA-----SAPEPPA 272
           VS ++        S + P     P+PP  P      T     PPP  A     + P P A
Sbjct: 460 VSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQA 519

Query: 273 EEEVAT 278
              +AT
Sbjct: 520 PPALAT 525


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,281,817
Number of Sequences: 37866
Number of extensions: 1608474
Number of successful extensions: 18286
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 218
Number of HSP's successfully gapped in prelim test: 883
Number of HSP's that attempted gapping in prelim test: 12375
Number of HSP's gapped (non-prelim): 4894
length of query: 722
length of database: 18,247,518
effective HSP length: 110
effective length of query: 612
effective length of database: 14,082,258
effective search space: 8618341896
effective search space used: 8618341896
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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