ITK 6087

Name: ITK	Sequence: fasta or formatted (620aa)		NCBI GI: 15718680
Description: IL2-inducible T-cell kinase		Referenced in: T cells Non-Receptor Tyrosine Kinase Pathways
Composition: Amino acid Percentage Count Longest homopolymer A alanine 5.0 31 2 C cysteine 2.6 16 2 D aspartate 4.5 28 2 E glutamate 8.4 52 2 F phenylalanine 4.4 27 2 G glycine 5.2 32 3 H histidine 2.6 16 1 I isoleucine 4.2 26 1 K lysine 6.8 42 2 L leucine 9.2 57 3 M methionine 1.9 12 2 N asparagine 4.5 28 3 P proline 4.8 30 2 Q glutamine 3.4 21 2 R arginine 6.3 39 2 S serine 7.3 45 2 T threonine 4.5 28 1 V valine 7.4 46 2 W tryptophan 2.1 13 2 Y tyrosine 5.0 31 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 IL2-inducible T-cell kinase TEC 0.582 tec protein tyrosine kinase BTK 0.495 Bruton agammaglobulinemia tyrosine kinase BMX 0.429 BMX non-receptor tyrosine kinase BMX 0.429 BMX non-receptor tyrosine kinase TXK 0.426 TXK tyrosine kinase LYN 0.232 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog is... FYN 0.232 protein-tyrosine kinase fyn isoform a LCK 0.231 lymphocyte-specific protein tyrosine kinase precurs... LCK 0.231 lymphocyte-specific protein tyrosine kinase precurs... YES1 0.230 viral oncogene yes-1 homolog 1 FYN 0.226 protein-tyrosine kinase fyn isoform b ABL1 0.226 c-abl oncogene 1, receptor tyrosine kinase isoform a... ABL1 0.226 c-abl oncogene 1, receptor tyrosine kinase isoform b... LYN 0.226 Yamaguchi sarcoma viral (v-yes-1) oncogene homolog ... HCK 0.226 hemopoietic cell kinase isoform p61HCK SRC 0.222 proto-oncogene tyrosine-protein kinase SRC SRC 0.222 proto-oncogene tyrosine-protein kinase SRC BLK 0.222 B lymphoid tyrosine kinase ABL2 0.222 arg tyrosine kinase isoform c ABL2 0.222 arg tyrosine kinase isoform b ABL2 0.222 arg tyrosine kinase isoform e ABL2 0.222 arg tyrosine kinase isoform d ABL2 0.222 arg tyrosine kinase isoform a FGR 0.222 proto-oncogene tyrosine-protein kinase FGR FGR 0.222 proto-oncogene tyrosine-protein kinase FGR FGR 0.222 proto-oncogene tyrosine-protein kinase FGR FRK 0.215 fyn-related kinase SRMS 0.197 src-related kinase lacking C-terminal regulatory tyr... FYN 0.195 protein-tyrosine kinase fyn isoform c Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.