BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7662018 PHD finger protein 3 [Homo sapiens] (2039 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7662018 PHD finger protein 3 [Homo sapiens] 4109 0.0 gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] 235 4e-61 gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] 199 2e-50 gi|47271475 SPOC domain containing 1 [Homo sapiens] 193 2e-48 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 84 1e-15 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 81 9e-15 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 74 1e-12 gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo ... 74 2e-12 gi|5803191 transcription elongation factor A 1 isoform 1 [Homo s... 74 2e-12 gi|45439355 transcription elongation factor A 1 isoform 2 [Homo ... 74 2e-12 gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] 73 3e-12 gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] 72 7e-12 gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] 72 7e-12 gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] 70 2e-11 gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] 70 2e-11 gi|41350335 transcription elongation factor A (SII), 3 [Homo sap... 69 4e-11 gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] 69 5e-11 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 69 6e-11 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 69 6e-11 gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] 67 1e-10 gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti... 67 2e-10 gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] 66 4e-10 gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] 65 5e-10 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 64 2e-09 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 63 3e-09 gi|52426743 cisplatin resistance-associated overexpressed protei... 63 3e-09 gi|19923485 cisplatin resistance-associated overexpressed protei... 63 3e-09 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 62 4e-09 gi|38505156 transcription elongation factor A protein 2 isoform ... 62 6e-09 gi|4507385 transcription elongation factor A protein 2 isoform a... 62 6e-09 >gi|7662018 PHD finger protein 3 [Homo sapiens] Length = 2039 Score = 4109 bits (10656), Expect = 0.0 Identities = 2039/2039 (100%), Positives = 2039/2039 (100%) Query: 1 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 60 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS Sbjct: 1 MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 60 Query: 61 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 120 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE Sbjct: 61 NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 120 Query: 121 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 180 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ Sbjct: 121 NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 180 Query: 181 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 240 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC Sbjct: 181 VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 240 Query: 241 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 300 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI Sbjct: 241 NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 300 Query: 301 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 360 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL Sbjct: 301 SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 360 Query: 361 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 420 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN Sbjct: 361 VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 420 Query: 421 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 480 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY Sbjct: 421 LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 480 Query: 481 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 540 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN Sbjct: 481 LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 540 Query: 541 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 600 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS Sbjct: 541 FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 600 Query: 601 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 660 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK Sbjct: 601 HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 660 Query: 661 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 720 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC Sbjct: 661 LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 720 Query: 721 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL 780 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL Sbjct: 721 GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL 780 Query: 781 DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS 840 DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS Sbjct: 781 DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS 840 Query: 841 SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE 900 SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE Sbjct: 841 SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE 900 Query: 901 MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT 960 MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT Sbjct: 901 MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT 960 Query: 961 KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS 1020 KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS Sbjct: 961 KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS 1020 Query: 1021 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA 1080 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA Sbjct: 1021 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA 1080 Query: 1081 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV 1140 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV Sbjct: 1081 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV 1140 Query: 1141 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST 1200 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST Sbjct: 1141 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST 1200 Query: 1201 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK 1260 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK Sbjct: 1201 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK 1260 Query: 1261 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD 1320 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD Sbjct: 1261 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD 1320 Query: 1321 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK 1380 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK Sbjct: 1321 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK 1380 Query: 1381 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL 1440 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL Sbjct: 1381 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL 1440 Query: 1441 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN 1500 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN Sbjct: 1441 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN 1500 Query: 1501 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL 1560 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL Sbjct: 1501 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL 1560 Query: 1561 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV 1620 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV Sbjct: 1561 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV 1620 Query: 1621 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM 1680 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM Sbjct: 1621 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM 1680 Query: 1681 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ 1740 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ Sbjct: 1681 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ 1740 Query: 1741 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP 1800 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP Sbjct: 1741 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP 1800 Query: 1801 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH 1860 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH Sbjct: 1801 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH 1860 Query: 1861 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR 1920 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR Sbjct: 1861 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR 1920 Query: 1921 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG 1980 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG Sbjct: 1921 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG 1980 Query: 1981 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR Sbjct: 1981 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 >gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens] Length = 2240 Score = 235 bits (599), Expect = 4e-61 Identities = 255/952 (26%), Positives = 388/952 (40%), Gaps = 179/952 (18%) Query: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181 P++DLSP V V V+ + S A++S ++ S E +Q+ PK Sbjct: 942 PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001 Query: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213 SP PR P P ES FL+RL+ IWKGFI Sbjct: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061 Query: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273 NM SVAKFVTKAYPVSG +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R Sbjct: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121 Query: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333 F P TEE++++Y L++YFSSR R+GV ANN + VKD+YLIPL A D +P L+PF+GPG Sbjct: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181 Query: 1334 LELHRPNLLLGLIIRQKLKR---------------------------------------- 1353 LE RPN++LGL+I QK+KR Sbjct: 1182 LESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKP 1241 Query: 1354 -QHSACASTSHIAETPESAPPIALPPDKKSKIEVSTEEAPEEENDFFNSFTTVLHKQRNK 1412 ++ C++ + ++ TP +PP P + ++V + P + + T Sbjct: 1242 SKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAAS 1301 Query: 1413 PQQNLQEDLPTAVEPLMEV---TKQEPPKPLRFLPGVLIGWENQPTTLELANKPLPVDDI 1469 + + +E +++ K+ R PG G +P T A +P + Sbjct: 1302 STASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKT--TAEDGVPAPPL 1359 Query: 1470 LQSLLGTTGQVYDQAQSVMEQNTVKEIPFLNEQTNSKIEKTDNVEVTDGENKEIKVKVDN 1529 L ++ GQ + + +++ E+ + P+ E+ D V G E++ + Sbjct: 1360 LDPIVQQFGQ-FSKDKALEEEE--DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEA 1416 Query: 1530 ISESTDKSA---EIETSVVGSSSISAGSLTSLSLRG-------KPPDVSTEAFLTNLSIQ 1579 + ++ A E ET ++ + ++ L + +P + A +L Q Sbjct: 1417 AAAEREEVAYDPEDET-ILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQ 1475 Query: 1580 SKQEETVESKEKTLKRQLQEDQENNLQD-------------NQTSNSSPCRSNVGKGNID 1626 K E + + + KRQL+E +E Q + S P +S++ K + Sbjct: 1476 QKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELF 1535 Query: 1627 GNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCR---NGEKHMLPG 1683 S + A+ + Q N RDPRQA R T E + R G + LP Sbjct: 1536 QQEQQSADKPASLPPASQASN-HRDPRQA--RRLAAETGEGEGEPLSRLSARGAQGALPE 1592 Query: 1684 LSHNKEHLTEQINV---EEK------LCSAEKNSCVQQSDNLKVAQNSPS-VENIQTSQA 1733 ++ L Q + EEK S EK + D K + + S A Sbjct: 1593 RDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSA 1652 Query: 1734 EQAK----------PLQEDILMQNIETVHPF------RRGSAVATSHFEVGNTCPSEFPS 1777 A+ LQ +Q+ PF + A+ ++ +E S S Sbjct: 1653 RPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRS 1712 Query: 1778 KS---ITFTSRSTSPRTSTNFSPMRP-------QQPNLQHLKSSPP---------GFPFP 1818 S T R R +P+ P QP Q + P G FP Sbjct: 1713 SSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFP 1772 Query: 1819 GP----PNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQ 1874 GP P FP +++ P PP FG + P+ H P GP Sbjct: 1773 GPRGPAPPFPEENIASNDGPRGP---PPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPS 1829 Query: 1875 ---ASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRF 1923 R + P F + K DP G + + Q D P+N G +F Sbjct: 1830 YLGGPRGVAPSQFEERK----------DPHGEKREFQ-DAPYNEVTGAPAQF 1870 Score = 177 bits (449), Expect = 9e-44 Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%) Query: 916 AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974 +A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E + K+A IEKE+F+ F+ TD Sbjct: 660 SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718 Query: 975 AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034 +YK+KYRS+MFNLKDPKN LF +VL+ E++ L+R+ PEEL SKEL+ W+ R R Sbjct: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778 Query: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094 +E K E ++ T + ++E P+ + E E KS + Sbjct: 779 MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829 Query: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149 + SM KDTTSQHR HLFDLNCKIC G++ D+ +PKK K+ V + KH Sbjct: 830 LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889 Query: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187 + + D+ E E ES T+ P P Sbjct: 890 SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932 Score = 77.8 bits (190), Expect = 1e-13 Identities = 75/278 (26%), Positives = 116/278 (41%), Gaps = 34/278 (12%) Query: 1772 PSEFPSKSITFTSRSTSPRTST--NFSPMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMF 1829 P +F + + R T+ R F +R P + + +P F F G PQ M Sbjct: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQA---PQVMK 2020 Query: 1830 GFP-PHLPPPLLPPPGFGFAQNPMVPW----PPVV---HLPGQPQRMMGPLSQASRYIGP 1881 P P L P PP Q+ W PP PGQ G + A G Sbjct: 2021 PGPRPLLELPSHPP------QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGK 2074 Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQ 1941 + Y+ + +R D ++ + R DR+R + RER +W++ Sbjct: 2075 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRER---DWDR 2131 Query: 1942 ESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPK 2000 E R RD+ +D DR ++D+ER DRG + SR+ SRN +++ D+ + Sbjct: 2132 PREWDRHRDKDSSRDWDRNRERSANRDRER----EADRGKEWDRSRERSRNRERERDRRR 2187 Query: 2001 SEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 D + +ER++ K R+ E+ RDR DR+KSK Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDR-------KDRSKSK 2218 Score = 72.4 bits (176), Expect = 4e-12 Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%) Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770 + P+ C++PH NRFM+ C RC++WFHGDCVG+S ++ + + ++Y+C C Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323 Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822 +++ +E D Q ++ GD +C +G + + ++ D+ K + + Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377 Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867 K K+KI + + G G +S C ++ I K A ++ + + Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437 Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916 +EK + P++ + C G K S E K+ V+K V L A Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497 Query: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961 +S PS + ++ + L+ + T + + E+ AA A+K Sbjct: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548 Score = 61.6 bits (148), Expect = 7e-09 Identities = 65/243 (26%), Positives = 92/243 (37%), Gaps = 31/243 (12%) Query: 1790 RTSTNFSPMRPQQPNLQHLKSSPPGFPFPGP------PNFPPQSMFG-FPPHLPPPLLPP 1842 R S FS Q P+ H + P PGP P+ PPQ + PP L Sbjct: 1993 RGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSS 2052 Query: 1843 PGFGFAQNPMVPWPPVVHLPGQPQRMMGPL---SQASRY-IGPQNFY--------QVKDI 1890 G W G+ Q R+ +GP+ + + Sbjct: 2053 SAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASED 2112 Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKG-------DRQRFYSDSHHLKRERHE-KEWEQE 1942 RR ER W R+ R ++R + DR R S + +RE KEW++ Sbjct: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172 Query: 1943 SERHRRRDRSQD--KDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK 2000 ER R R+R +D +DRDR E +DK R R DR K+ +R D KP+ + Sbjct: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESAR--DPKPEASR 2230 Query: 2001 SED 2003 + D Sbjct: 2231 ASD 2233 Score = 60.1 bits (144), Expect = 2e-08 Identities = 72/318 (22%), Positives = 116/318 (36%), Gaps = 66/318 (20%) Query: 1768 GNTCPSEFPSKSITFTSRSTSPRTS--TNFSPMRPQQPN-LQHLKSSPPGFPFPGPPNFP 1824 G PS+F + PR + F R PN + + P F PGP Sbjct: 1905 GGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNF-MPGPRGIQ 1963 Query: 1825 PQSMFGFPPHLPPPLL-----PPPGFGFAQNPMVPW-------PPVVHLPGQPQRMMGPL 1872 PQ H PP P FG + P+ P H GQ ++M P Sbjct: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGS-APFSEKNEQTPSRFHFQGQAPQVMKP- 2021 Query: 1873 SQASRYIGPQNFYQVKDIRRPERRHSDPWGRQ-----------------DQQQLDRPFNR 1915 GP+ ++ P + D W D Q F Sbjct: 2022 -------GPRPLLELPS--HPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFRE 2072 Query: 1916 GKG-----------DRQRFYSDSHHLKRERHEKEWEQESERHRRRDR----SQDKDRDRK 1960 GKG R+RF E + + +R R R+R S+++D DR Sbjct: 2073 GKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRP 2132 Query: 1961 SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEK 2020 + H+DK+ +R DR + A+RD ++ + + +++++ +ER +++ RE ++ Sbjct: 2133 REWDRHRDKDSSR--DWDRNRERSANRD-----REREADRGKEWDRSRERSRNRERERDR 2185 Query: 2021 DRDRYHKDRDHTDRTKSK 2038 RDR DR K++ Sbjct: 2186 RRDRDRSRSRERDRDKAR 2203 >gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens] Length = 1189 Score = 199 bits (507), Expect = 2e-50 Identities = 111/240 (46%), Positives = 147/240 (61%), Gaps = 34/240 (14%) Query: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181 P++DLSP V V V+ + S A++S ++ S E +Q+ PK Sbjct: 942 PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001 Query: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213 SP PR P P ES FL+RL+ IWKGFI Sbjct: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061 Query: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273 NM SVAKFVTKAYPVSG +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R Sbjct: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121 Query: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333 F P TEE++++Y L++YFSSR R+GV ANN + VKD+YLIPL A D +P L+PF+GPG Sbjct: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181 Score = 177 bits (449), Expect = 9e-44 Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%) Query: 916 AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974 +A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E + K+A IEKE+F+ F+ TD Sbjct: 660 SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718 Query: 975 AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034 +YK+KYRS+MFNLKDPKN LF +VL+ E++ L+R+ PEEL SKEL+ W+ R R Sbjct: 719 NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778 Query: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094 +E K E ++ T + ++E P+ + E E KS + Sbjct: 779 MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829 Query: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149 + SM KDTTSQHR HLFDLNCKIC G++ D+ +PKK K+ V + KH Sbjct: 830 LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889 Query: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187 + + D+ E E ES T+ P P Sbjct: 890 SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932 Score = 72.4 bits (176), Expect = 4e-12 Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%) Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770 + P+ C++PH NRFM+ C RC++WFHGDCVG+S ++ + + ++Y+C C Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323 Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822 +++ +E D Q ++ GD +C +G + + ++ D+ K + + Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377 Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867 K K+KI + + G G +S C ++ I K A ++ + + Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437 Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916 +EK + P++ + C G K S E K+ V+K V L A Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497 Query: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961 +S PS + ++ + L+ + T + + E+ AA A+K Sbjct: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548 >gi|47271475 SPOC domain containing 1 [Homo sapiens] Length = 1216 Score = 193 bits (490), Expect = 2e-48 Identities = 152/473 (32%), Positives = 225/473 (47%), Gaps = 74/473 (15%) Query: 887 GEKASKPGTHEKQEMKKKKVEKGVLNVHPAASAS----KPSAD-QIRQSVRHSLKDILMK 941 G+ +S P + M+ E+ L P SA KPS +R +V S++++L Sbjct: 566 GDPSSDPACSQSGPME---AEEDSLPEQPEDSAQLQQEKPSLYIGVRGTVVRSMQEVLWT 622 Query: 942 RLTD-SNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKV 1000 RL + + + EE +A IE L+ + T+ +YK KYRSL+FNL+DP+N LF KV Sbjct: 623 RLRELPDPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLDLFLKV 682 Query: 1001 LKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIE 1060 + G+VTP L+RMS +LA +ELA WR +E + + +IE++Q+E R P +K+THKGE+E Sbjct: 683 VHGDVTPYDLVRMSSMQLAPQELARWRDQEEKRGLNIIEQQQKEPCRLPASKMTHKGEVE 742 Query: 1061 IESDAPMKEQEAAMEIQEPAANKSLEKPE-GSEKQKEEVDSMSKDTTSQHRQHLFDLNCK 1119 I+ D +Q +E L P+ + + + S+DTT QH H D NC Sbjct: 743 IQRD---MDQTLTLE--------DLVGPQMFMDCSPQALPIASEDTTGQHDHHFLDPNCH 791 Query: 1120 ICIGRMAPPVDDLSPKKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESP 1179 IC D P S+ S A S NI + Sbjct: 792 IC--------KDWEP-------------SNELLGSFEAAKSCGDNIFQKALSQ------- 823 Query: 1180 KSTFSPAPRPEMPGTVEVESTF-------------LARLNFI-----WKGFINMPSVAKF 1221 +P P PEMP T E+ T A + W+G ++M S+ +F Sbjct: 824 ----TPMPAPEMPKTRELSPTEPQDRVPPSGLHVPAAPTKALPCLPPWEGVLDMFSIKRF 879 Query: 1222 VTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEED 1281 +A VSG L + LP I+ G I VWD + I + K++CVVR P D Sbjct: 880 RARAQLVSGHSCRLVQALPTVIRSAGCIPSNIVWDLLASICPAKAKDVCVVRLCPHGARD 939 Query: 1282 QISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPGL 1334 + LL++Y + R+R+G+A+ + M L+PL A +P L P GPGL Sbjct: 940 TQNCRLLYSYLNDRQRHGLAS---VEHMGMVLLPLPAFQPLPTRLRPLGGPGL 989 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 84.3 bits (207), Expect = 1e-15 Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 +D RR ERR R+D++ +R R + DR+R RER EKE E E ER R Sbjct: 656 RDERREERRVDRVDDRRDERARERDRERER-DRERERERERERDRER-EKERELERERAR 713 Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 R+R ++K+RDR+ + D+ER R DR + + R+ R +++ ++ + + E++ Sbjct: 714 EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERE 773 Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 +ER + + +E E+ RD KD+ DR + + Sbjct: 774 RERARERDKERERQRDWEDKDKGRDDRREKR 804 Score = 68.6 bits (166), Expect = 6e-11 Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 21/169 (12%) Query: 1888 KDIRRPERRHSDP---WGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944 +D R ++R S P GR D+ + D + DR D +R+R E E++ E Sbjct: 632 RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR---ERERDRE 688 Query: 1945 RHRRRDRSQDKDRDR-------KSRE-EGHKDKERARLSHGDRGTDGKASRDSRNVDKKP 1996 R R R+R +D++R++ ++RE E ++KER R DR D + R+ +K Sbjct: 689 RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748 Query: 1997 DKPKSEDYEKDKEREKSKHREGEKDRDR-------YHKDRDHTDRTKSK 2038 + + E+ E+++ERE+ + RE E++R+R + RD D+ K + Sbjct: 749 REREREERERERERERERERERERERERARERDKERERQRDWEDKDKGR 797 Score = 58.2 bits (139), Expect = 8e-08 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 5/153 (3%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949 R ER R+ +++L+R R + +R+R R+R H++E E+E ER R + Sbjct: 689 RERERERERDREREKERELERERARER-EREREKERDRERDRDRDHDRERERERERDREK 747 Query: 1950 DRS---QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 +R ++++R+R+ E +++ER R +R + + RD + DK D + + E Sbjct: 748 EREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEI 807 Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 ++R + K + RY + + R KR Sbjct: 808 REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR 840 Score = 55.5 bits (132), Expect = 5e-07 Identities = 31/142 (21%), Positives = 67/142 (47%), Gaps = 1/142 (0%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R ER + R+ +++ DR +R + D R RE+ + +E ER R R+ Sbjct: 705 RELERERAREREREREKERDRERDRDR-DHDRERERERERDREKEREREREERERERERE 763 Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKER 2010 R ++++R+R+ +DKER R + G+ R + + + D+ + +++ K + Sbjct: 764 RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823 Query: 2011 EKSKHREGEKDRDRYHKDRDHT 2032 ++ ++ R + R+H+ Sbjct: 824 KRYRNEGSPSPRQSPKRRREHS 845 Score = 55.1 bits (131), Expect = 7e-07 Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 14/154 (9%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R ER R ++ DR +R + +R+R +RER E+E E+E ER R R+ Sbjct: 711 RAREREREREKERDRERDRDRDHDRER-ERERERDREKEREREREERERERERERERERE 769 Query: 1951 RSQDKDRDR-----KSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 R ++++R R + R+ +DK++ R DR + R+ RN D+ KS+ Sbjct: 770 RERERERARERDKERERQRDWEDKDKGR---DDRREKREEIREDRNPRDGHDERKSKKRY 826 Query: 2006 KDK-----EREKSKHREGEKDRDRYHKDRDHTDR 2034 +++ + + RE D D Y+ D ++ Sbjct: 827 RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEK 860 Score = 52.8 bits (125), Expect = 3e-06 Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 26/131 (19%) Query: 1933 ERHEKEWEQESE---RHRRRDRSQDKDRDRKS----REEGHKD-------KERARLSHGD 1978 ER ++ ++S RH RDR +++RD++ R +G D +E R+ D Sbjct: 610 ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669 Query: 1979 RGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREK----------SKHREGEKDRDRYH-K 2027 D +A R ++ ++ + + E+D+EREK + RE EK+RDR + Sbjct: 670 DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729 Query: 2028 DRDHTDRTKSK 2038 DRDH DR + + Sbjct: 730 DRDH-DRERER 739 Score = 50.4 bits (119), Expect = 2e-05 Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 12/137 (8%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962 R DQ + P DRQ S S +++ S RDR Q++DR R Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309 Query: 1963 EEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKD 2021 E +ER R R D A +D RN D+ D+ + E+++ERE+ K R+ +++ Sbjct: 1310 E-----RERERRDTRQREWDRDADKDWPRNRDR--DRLR----ERERERERDKRRDLDRE 1358 Query: 2022 RDRYHKDRDHTDRTKSK 2038 R+R D DR + + Sbjct: 1359 RERLISDSVERDRDRDR 1375 Score = 50.1 bits (118), Expect = 2e-05 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 24/173 (13%) Query: 1886 QVKDIRRPERR---HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQE 1942 ++++ R E R +D GR + + P +G R DSH H+ WE Sbjct: 542 EIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGS-QIDSHSSNSNYHDS-WETR 599 Query: 1943 S---ERHR-----RRDRSQDKDRDRKSREEGHKD-KERAR-----LSHGDRGTDGKAS-- 1986 S ER R RD+++D +R+ E +D +ER + + H R + + Sbjct: 600 SSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDER 659 Query: 1987 RDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 R+ R VD+ D+ E+D+ERE+ + RE E++R+R DR+ + +R Sbjct: 660 REERRVDRVDDRRDERARERDRERERDRERERERERER---DREREKERELER 709 Score = 47.8 bits (112), Expect = 1e-04 Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 20/162 (12%) Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945 ++ ++R E S RQD + + + DRQ R+R ++ E +R Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309 Query: 1946 HRRRDRSQDKDR--DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003 R R+R + R DR + ++ ++++R RL +R + RD +D++ ++ S+ Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRD---LDRERERLISDS 1366 Query: 2004 YEKDKEREKSK---------------HREGEKDRDRYHKDRD 2030 E+D++R++ + EGE +RD RD Sbjct: 1367 VERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408 Score = 43.9 bits (102), Expect = 0.002 Identities = 46/186 (24%), Positives = 75/186 (40%), Gaps = 28/186 (15%) Query: 1860 HLPGQPQRMMGPLSQASRYIGPQ-----NFYQVKDIRRPERRHSDPWGRQDQQQLDRPFN 1914 H P P+R P R + P + Y + P+R+ S P R ++ Sbjct: 345 HSPS-PRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMRE------ 397 Query: 1915 RGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDR-----KSREEGHKDK 1969 +G+ D +R S SH + ER E + +RDR +D +R +S H+D Sbjct: 398 KGRHDHERT-SQSHDRRHERRE-------DTRGKRDREKDSREEREYEQDQSSSRDHRDD 449 Query: 1970 ERARLSHGDR-GTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRY-HK 2027 R R D + R+ R+ D + DY +D +E R+ RD + ++ Sbjct: 450 REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRD-TKESRDPRDSRSTRDAHDYR 508 Query: 2028 DRDHTD 2033 DR+ D Sbjct: 509 DREGRD 514 Score = 42.0 bits (97), Expect = 0.006 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 22/160 (13%) Query: 1881 PQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE 1940 P YQ + + P RR + P+ L P + R R S R HE+ + Sbjct: 355 PSPSYQ-RTLTPPLRRSASPY---PSHSLSSPQRKQSPPRHR--SPMREKGRHDHERTSQ 408 Query: 1941 QESERHRRRDRSQDK-DRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999 RH RR+ ++ K DR++ SREE +++++ +SRD R+ D++P Sbjct: 409 SHDRRHERREDTRGKRDREKDSREEREYEQDQS------------SSRDHRD-DREPRDG 455 Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + +D R++ + R+ RD + RD++ TK R Sbjct: 456 RDRRDARD-TRDRRELRDSRDMRDS-REMRDYSRDTKESR 493 Score = 40.8 bits (94), Expect = 0.014 Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 17/161 (10%) Query: 1873 SQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKR 1932 S +SR P++ QV R D +D+ + DR +R+R D+ + Sbjct: 1272 SHSSRRSSPESDRQVHS-RSGSFDSRDRLQERDRYEHDR-------ERERERRDTRQREW 1323 Query: 1933 ERH-EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARL----SHGDRGTDGKASR 1987 +R +K+W + +R R R+R ++++RD++ D+ER RL DR D + Sbjct: 1324 DRDADKDWPRNRDRDRLRERERERERDKRR----DLDRERERLISDSVERDRDRDRDRTF 1379 Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKD 2028 +S ++ + E +++ E + D++R KD Sbjct: 1380 ESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420 Score = 35.0 bits (79), Expect = 0.75 Identities = 40/177 (22%), Positives = 68/177 (38%), Gaps = 21/177 (11%) Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQ 1941 Q ++ KD R +RR R+D+ D R R R + + +E Sbjct: 787 QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846 Query: 1942 ESERHRRRDRSQDKDR---------DRKSREEGHKDKER-ARLSHGDRGTDGKASRDSRN 1991 +S+ + D +K R + +S H ++R R DR + K S SR Sbjct: 847 DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKES--SRR 904 Query: 1992 VDKKPDKPKSEDYEKDKER----EKSKHREGE-----KDRDRYHKDRDHTDRTKSKR 2039 +++ K K +K +E+ E S+ R + + DR DR H + K + Sbjct: 905 YEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAK 961 Score = 35.0 bits (79), Expect = 0.75 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 20/115 (17%) Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG-------------TDGKASRDSRN 1991 R R + +S + +RKSR + K E +R + DR +D + S + Sbjct: 1233 RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292 Query: 1992 VDKKPDKPKSEDYEKDKEREK----SKHREGEKDRDR---YHKDRDHTDRTKSKR 2039 D + + + YE D+ERE+ ++ RE ++D D+ ++DRD + +R Sbjct: 1293 FDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERER 1347 Score = 32.0 bits (71), Expect = 6.3 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 22/142 (15%) Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG- 1977 DRQ + + K ER E E + + + S DK R++ E + + + + H Sbjct: 884 DRQGRWKEEDR-KPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942 Query: 1978 --DRGTDGKASRDSRN---VDKKPDKPK---------------SEDYEKDKEREKSKHRE 2017 DR T +A +++ + KKP K K SED + ++ K + Sbjct: 943 SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002 Query: 2018 GEKDRDRYHKDRDHTDRTKSKR 2039 EK R + D D +D +++ Sbjct: 1003 IEKKRKKSKGDSDISDEEAAQQ 1024 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 81.3 bits (199), Expect = 9e-15 Identities = 42/153 (27%), Positives = 82/153 (53%), Gaps = 7/153 (4%) Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945 ++ R ++ + G++++++ + R + +R+R + E+E E+E E+ Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339 Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 R R+R +D+DRDR + +D+ER DR D + S D RN D+ + KS D E Sbjct: 340 ERERERERDRDRDRTKERDRDRDRER------DRDRDRERSSD-RNKDRSRSREKSRDRE 392 Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 +++ERE+ + RE E++R+R + +R + + Sbjct: 393 RERERERERERERERERERERERERERERERER 425 Score = 64.3 bits (155), Expect = 1e-09 Identities = 35/152 (23%), Positives = 76/152 (50%), Gaps = 13/152 (8%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 ++ R R + R+ +++ +R + K + D + + +++ ++E +R R Sbjct: 310 RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369 Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 R+RS D+++DR E +D+ER R +R +++ ++ + + E++ Sbjct: 370 DRERSSDRNKDRSRSREKSRDRERERERERER-------------ERERERERERERERE 416 Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +ERE+ + RE +K RDR + D +R K +R Sbjct: 417 REREREREREKDKKRDREEDEEDAYERRKLER 448 Score = 61.2 bits (147), Expect = 1e-08 Identities = 47/169 (27%), Positives = 77/169 (45%), Gaps = 30/169 (17%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949 R ER R ++ DR R + DR R S + R R EK ++E ER R R Sbjct: 341 RERERERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSRDRERERERER 399 Query: 1950 DRSQDKDRDRKSREEGHKDKERARL----SHGDRGTDGKASRDSRNVDKK---------- 1995 +R ++++R+R+ E +++ER R DR D + + + R +++K Sbjct: 400 EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQE 459 Query: 1996 -------PDKPKSEDYEKDKEREKSKHREGEKDRDR-------YHKDRD 2030 ++ K+ +YEK+ ERE+ + RE K+ R Y DRD Sbjct: 460 RLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508 Score = 39.3 bits (90), Expect = 0.040 Identities = 23/106 (21%), Positives = 56/106 (52%), Gaps = 4/106 (3%) Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGD 1978 D ++Y S KR R ++ + ER R+R++ + ++ ++ EGH D + A L + Sbjct: 508 DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPD-AELQRME 566 Query: 1979 RGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDR 2024 + + R + ++P+ + E+ +++KE ++ + E E++ ++ Sbjct: 567 QEAE---RRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609 Score = 38.9 bits (89), Expect = 0.052 Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%) Query: 1807 HLKSSPPGFPFPGPPNFPPQSMFGFPPHLPP--PLLPPPGFGFAQNPMVPWPPV 1858 HL P G P PP PP GFPP +PP P++P P A P V P V Sbjct: 6 HLNRPPMGIPAL-PPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTV 58 Score = 37.0 bits (84), Expect = 0.20 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 12/70 (17%) Query: 1817 FPGPPNFPPQSMFGFPPHLPPPLLP------PPGFGFAQNPMVPWPPVVHLPGQPQRMMG 1870 FP N PP + PP +PPP P PPG PM+P P + P P ++ Sbjct: 3 FPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPG-----TPMIPVPMSIMAPA-PTVLVP 56 Query: 1871 PLSQASRYIG 1880 +S +++G Sbjct: 57 TVSMVGKHLG 66 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 74.3 bits (181), Expect = 1e-12 Identities = 46/155 (29%), Positives = 85/155 (54%), Gaps = 14/155 (9%) Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951 R R + R++++Q +R +R R+R H KR+RH E++ +R + R+R Sbjct: 54 RERNRQKERERRREKRQTERETDR---KRERRREKDRHRKRDRHR---ERQRDREKERER 107 Query: 1952 SQDKDRDRKSREEGHKDKERARLS--HGDRG----TDGKASRD-SRNVDKKPDKPKSEDY 2004 D++RDR+ +E ++ KER R + G+RG TDG+ R+ R+ +K+ ++ + Sbjct: 108 QTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167 Query: 2005 EKDKEREKSKHREGEKDR-DRYHKDRDHTDRTKSK 2038 ++ ER + K RE EK+R +R ++R K++ Sbjct: 168 QRQTERNRQKEREREKNRQERRERERQREKENKTE 202 Score = 73.9 bits (180), Expect = 1e-12 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 4/154 (2%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKG-DRQRFYSDSHHLKRERHEKEWEQESERH 1946 +D R+ ER RQ + + DR R + R+R + KRER E+E E+E ER Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER-ERERERERERQ 330 Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLS--HGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R +R ++K+R+RK + + D+ER R + G R + + R+ + + + + Sbjct: 331 RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390 Query: 2005 EKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 ++D++R+K + R+ EKDRD + +R K + Sbjct: 391 DRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424 Score = 73.6 bits (179), Expect = 2e-12 Identities = 41/152 (26%), Positives = 78/152 (51%), Gaps = 2/152 (1%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 ++ R ERR + ++ + DR RG+ +R+R +R+R + + E++ +R Sbjct: 181 REKNRQERRERERQREKENKTEDRHSERGR-ERERERETETETERKR-QTDRERDRQRKT 238 Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 R+R + +R+R S E +DKER R DR D + R D+K + D E + Sbjct: 239 EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298 Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 ++RE+ + RE E++R+R + +R + ++ Sbjct: 299 RKRERQRERERERERNRKRERERERERERERQ 330 Score = 71.2 bits (173), Expect = 9e-12 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949 RR ER R+ Q++ +R R K +R+R +RE E++ E+E ER R+R Sbjct: 289 RRTERDRETERKRERQRERERERERNRKRERERERERERERQRET-ERDREKERERKRKR 347 Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSE----DYE 2005 D++R+R++ EG + ER R +R R+ R D+ D+ K + + Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407 Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 +D +RE K RE EKDR+ +R K K Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQK 440 Score = 68.2 bits (165), Expect = 8e-11 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R ER + ++Q DR +R + + + + E E ++E ER R RD Sbjct: 210 RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269 Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPDKPKSEDYEKD 2007 R D+DR +K RE D++R R + DR T+ K R R ++ + + + E++ Sbjct: 270 R--DRDRRQKERER-QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326 Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +ER++ R+ EK+R+R K + DR ++++ Sbjct: 327 RERQRETERDREKERERKRKRQTEMDRERNRQ 358 Score = 67.4 bits (163), Expect = 1e-10 Identities = 43/153 (28%), Positives = 87/153 (56%), Gaps = 16/153 (10%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 +D + R +D R+ Q+Q +R NR K +R+R + ++ER E+E ++E E ++ Sbjct: 153 RDAEKERERQTD---RERQRQTER--NRQK-EREREKN-----RQERRERERQREKE-NK 200 Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 DR ++ R+R+ E + ER R + +R K R+ +K+ ++ ++ + E + Sbjct: 201 TEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER---EKQAERERASERETE 257 Query: 2008 KEREKSKHREGEKDRDRYHKDRD-HTDRTKSKR 2039 +++E+ + R+ ++DRDR K+R+ TDR + +R Sbjct: 258 RDKERERERDRDRDRDRRQKERERQTDRKRQRR 290 Score = 66.6 bits (161), Expect = 2e-10 Identities = 34/109 (31%), Positives = 60/109 (55%), Gaps = 2/109 (1%) Query: 1929 HLKRERHEKEWEQESERHRRRDRSQ-DKDRDRKSREEGHKDKERARLSHGDRGTDGKASR 1987 H + ++E ++ ER RRR++ Q +++ DRK KD+ R R H +R D + R Sbjct: 46 HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105 Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTK 2036 + R D++ D+ + ++ + KERE+ REGE+ RDR + +R + Sbjct: 106 E-RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153 Score = 66.6 bits (161), Expect = 2e-10 Identities = 40/159 (25%), Positives = 84/159 (52%), Gaps = 11/159 (6%) Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951 + R D +D++Q +R + ++R D ++ ++E E+E ER+R+R+R Sbjct: 260 KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319 Query: 1952 SQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPDKPKSEDYEKDK 2008 ++++R+R+ + E +D+E+ R R T+ R+ R ++ ++ + + E+D+ Sbjct: 320 ERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR 379 Query: 2009 -------EREKSKHREGEKDRDRY-HKDRDHTDRTKSKR 2039 ERE+ + R+ +K+R+R KDRD T+ +R Sbjct: 380 QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418 Score = 63.2 bits (152), Expect = 3e-09 Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 4/124 (3%) Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGD 1978 DR+R +RE+ + E E + +R RRR++ + + RDR + ++KER R + + Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112 Query: 1979 RGTDGKASRD---SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRT 2035 R + R+ R + + + + D + D +RE+ + R+ EK+R+R DR+ +T Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-QTDRERQRQT 171 Query: 2036 KSKR 2039 + R Sbjct: 172 ERNR 175 Score = 60.5 bits (145), Expect = 2e-08 Identities = 37/154 (24%), Positives = 77/154 (50%), Gaps = 6/154 (3%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949 R +R+ R+ Q + +R R + D++R R+R +KE E++++R R+R Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289 Query: 1950 ----DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDY 2004 DR ++ R+R+ E +++ R R +R + + R++ R+ +K+ ++ + Sbjct: 290 RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349 Query: 2005 EKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 E D+ER + REG + +R + DR ++ Sbjct: 350 EMDRERNRQTGREGRRQAERERERERERDRQSAR 383 Score = 60.1 bits (144), Expect = 2e-08 Identities = 56/204 (27%), Positives = 93/204 (45%), Gaps = 54/204 (26%) Query: 1889 DIRRPERRHSDPWGRQD---QQQLDRPFNRGKG-----DRQRFYSDSHHLKRERH-EKEW 1939 D +R RR D ++D ++Q DR R + DRQR + +RER E+E Sbjct: 76 DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135 Query: 1940 EQ--------ESERHRRRD----RSQDKDRDRKSREEGHKDKERARLS------------ 1975 E+ + ER R+RD R + DR+R+ + E ++ KER R Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195 Query: 1976 ---------HGDRGTDGKASRDS-------RNVDKKPDKPKSEDYEKDK--EREKSKHRE 2017 H +RG + + R++ R D++ D+ + + E++K ERE++ RE Sbjct: 196 EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255 Query: 2018 GEKDRDRYH---KDRDHTDRTKSK 2038 E+D++R +DRD R K + Sbjct: 256 TERDKERERERDRDRDRDRRQKER 279 Score = 60.1 bits (144), Expect = 2e-08 Identities = 38/151 (25%), Positives = 78/151 (51%), Gaps = 8/151 (5%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R+ ER R+ Q++ +R + +R+R + RER+ ++ +E R R+ Sbjct: 315 RKRERERERERERERQRETERDREK---ERERKRKRQTEMDRERN-RQTGREGRRQAERE 370 Query: 1951 RSQDKDRDRKS---REEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 R ++++RDR+S REE +D++R R +R T+ K R +K+ ++ K + E+ Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTE-KDRDGQRETEKQREREKDRESERG 429 Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 +ER + + ++ ++RDR + R + + Sbjct: 430 RERGREREKQKGRERDRERQTDRQAGRQRKR 460 Score = 59.3 bits (142), Expect = 4e-08 Identities = 43/173 (24%), Positives = 87/173 (50%), Gaps = 17/173 (9%) Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH------ 1935 +N + ++ RR +R+ R+ +++ ++ +R K DR R +RER Sbjct: 56 RNRQKERERRREKRQTERETDRKRERRREKDRHR-KRDRHRERQRDREKERERQTDRERD 114 Query: 1936 ---EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RN 1991 EKE ++ ER R +R ++ RDR++ + ++++R +R TD + R + RN Sbjct: 115 RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174 Query: 1992 VDKKPDKPKSEDYEKDKEREKSKH-----REGEKDRDRYHKDRDHTDRTKSKR 2039 K+ ++ K+ +++ER++ K R E+ R+R ++R+ T+ KR Sbjct: 175 RQKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERETETETERKR 226 Score = 46.6 bits (109), Expect = 2e-04 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 5/113 (4%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK-----EWEQESERHRRRDRSQDKDR 1957 R+ +++ DR R + +R+R +RER + + E E +R R +DR ++ R Sbjct: 371 RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430 Query: 1958 DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKER 2010 +R E K +ER R DR + R + V+ P +S + D R Sbjct: 431 ERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483 Score = 39.3 bits (90), Expect = 0.040 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 5/104 (4%) Query: 1874 QASRYIGPQNFYQVKDIRRPERRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKR 1932 + +R G + Q + R ER R+ ++++ DR +R K +R+R +R Sbjct: 354 ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK-ERERQTEKDRDGQR 412 Query: 1933 E---RHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERAR 1973 E + E+E ++ESER R R R ++K + R+ E D++ R Sbjct: 413 ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456 Score = 35.4 bits (80), Expect = 0.57 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 16/99 (16%) Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 RRR SQ+ R R+ + HKD + DR + + R+ R +K + D ++ Sbjct: 28 RRRPGSQESPR-RRGLGQAHKDADG-----DDRERNRQKERERRR--EKRQTERETDRKR 79 Query: 2007 DKEREKSKHREGEKDRDR-YHKDRD-----HTDRTKSKR 2039 ++ REK +HR+ +DR R +DR+ TDR + ++ Sbjct: 80 ERRREKDRHRK--RDRHRERQRDREKERERQTDRERDRQ 116 >gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo sapiens] Length = 287 Score = 73.6 bits (179), Expect = 2e-12 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%) Query: 869 SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927 S EK K+ +T ++ + + +K E + + ++ PS +D + Sbjct: 67 STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 126 Query: 928 RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987 R R L L R D + + ++ ++ ++IE+ ++ R+TD KYKN+ RS + N Sbjct: 127 RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 183 Query: 988 LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035 LKD KN L K VL G + PD RM+ EE+AS EL R+ + I Sbjct: 184 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 231 >gi|5803191 transcription elongation factor A 1 isoform 1 [Homo sapiens] Length = 301 Score = 73.6 bits (179), Expect = 2e-12 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%) Query: 869 SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927 S EK K+ +T ++ + + +K E + + ++ PS +D + Sbjct: 81 STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 140 Query: 928 RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987 R R L L R D + + ++ ++ ++IE+ ++ R+TD KYKN+ RS + N Sbjct: 141 RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 197 Query: 988 LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035 LKD KN L K VL G + PD RM+ EE+AS EL R+ + I Sbjct: 198 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 245 >gi|45439355 transcription elongation factor A 1 isoform 2 [Homo sapiens] Length = 280 Score = 73.6 bits (179), Expect = 2e-12 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%) Query: 869 SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927 S EK K+ +T ++ + + +K E + + ++ PS +D + Sbjct: 60 STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 119 Query: 928 RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987 R R L L R D + + ++ ++ ++IE+ ++ R+TD KYKN+ RS + N Sbjct: 120 RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 176 Query: 988 LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035 LKD KN L K VL G + PD RM+ EE+AS EL R+ + I Sbjct: 177 LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 224 >gi|169167715 PREDICTED: hypothetical protein [Homo sapiens] Length = 285 Score = 72.8 bits (177), Expect = 3e-12 Identities = 45/163 (27%), Positives = 84/163 (51%), Gaps = 15/163 (9%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRER-----HEKEWEQESE 1944 R +R+ + R+ +++++ +R K DR+R KRER E E E++ E Sbjct: 66 RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125 Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R R+RDR ++KDR+R+ + E DK+R + DR + + R D++ ++ K + Sbjct: 126 RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185 Query: 2005 EKDKEREKSKHREG---------EKDRDRYHKDRDHTDRTKSK 2038 +D++RE+ + +E E+++DRY + DR K + Sbjct: 186 RRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228 Score = 59.7 bits (143), Expect = 3e-08 Identities = 41/148 (27%), Positives = 77/148 (52%), Gaps = 15/148 (10%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDK--DRDRK 1960 R+ Q++ +R R K +R R R+R K ++E +R R RDR +++ DRDR+ Sbjct: 60 RERQRERERQRKRAK-ERHREKDREIEKDRDRQRKR-DRERQRWRDRDRKRERWGDRDRE 117 Query: 1961 SREEGHKDKERARLSHGDRGTDGKASRD-----SRNVDKKPDKPKSEDY-----EKDKER 2010 + E +++ER R ++ + + R+ R ++ + D+ + + +D+ER Sbjct: 118 TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177 Query: 2011 EKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 E+ K RE +DRDR + R+ DR + + Sbjct: 178 ERQKQRETRRDRDR-ERQREKEDRERDR 204 Score = 53.9 bits (128), Expect = 2e-06 Identities = 36/120 (30%), Positives = 67/120 (55%), Gaps = 15/120 (12%) Query: 1931 KRERHEKEWEQESERHRRRDRSQD----KDRDRKSREEGH----KDKERARLSHGDRGTD 1982 +RER ++E E++ +R + R R +D KDRDR+ + + +D++R R GDR + Sbjct: 59 ERER-QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117 Query: 1983 GKASRDSRNVDKKPDKPKSEDYEKDKERE----KSKHREGEKDRDRYHKDRDHTDRTKSK 2038 + R +++ D+ + +D E+ ++RE K + E EKDRDR ++ T+R + + Sbjct: 118 TETERQEER-ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDR-EREMGETERYRDR 175 Score = 50.8 bits (120), Expect = 1e-05 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 6/104 (5%) Query: 1941 QESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK 2000 +E ER R R+R + + ++R ++ +K+R R DR RD R ++ D+ + Sbjct: 58 RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRD-RKRERWGDRDR 116 Query: 2001 SEDYEKDKEREKSKHREGEKDRDRYHK-----DRDHTDRTKSKR 2039 + E+ +ERE+ + R+ EKDR+R + D+D T+ R Sbjct: 117 ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDR 160 Score = 38.1 bits (87), Expect = 0.089 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%) Query: 1903 RQDQQQLDRPFNRGKG------DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRS--QD 1954 R+ + + DR R G DR+R +R+R + ++ +R R RDR ++ Sbjct: 152 REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211 Query: 1955 KDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988 KDR R+ +DKER R ++ D + + D Sbjct: 212 KDRYRERETGRDRDKERDRERQREKDRDRQKAID 245 >gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens] Length = 562 Score = 71.6 bits (174), Expect = 7e-12 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 37/234 (15%) Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770 + P+ C++PH NRFM+ C RC++WFHGDCVG+S ++ + + ++Y+C C Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323 Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822 +++ +E D Q ++ GD +C +G + + ++ D+ K + + Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377 Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867 K K+KI + + G G +S C ++ I K A ++ + + Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437 Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGVLNVHPAAS 918 +EK + P++ + C G K S E K+ V+K V V PA S Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV--VVPARS 489 >gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens] Length = 562 Score = 71.6 bits (174), Expect = 7e-12 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 37/234 (15%) Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770 + P+ C++PH NRFM+ C RC++WFHGDCVG+S ++ + + ++Y+C C Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323 Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822 +++ +E D Q ++ GD +C +G + + ++ D+ K + + Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377 Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867 K K+KI + + G G +S C ++ I K A ++ + + Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437 Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGVLNVHPAAS 918 +EK + P++ + C G K S E K+ V+K V V PA S Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV--VVPARS 489 >gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens] Length = 520 Score = 70.5 bits (171), Expect = 2e-11 Identities = 63/222 (28%), Positives = 100/222 (45%), Gaps = 35/222 (15%) Query: 1820 PPNFPPQSMFGFPP-HLPPP-LLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASR 1877 PP FPP G PP HLPPP LPPP P++P P PG P + P ++ Sbjct: 283 PPFFPP----GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES-- 336 Query: 1878 YIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK 1937 G + Y + R + P+G + P G D+ K Sbjct: 337 --GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT--------SK 375 Query: 1938 EWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD 1997 +W+ + R + RDR +D+DR+R + +D+ER R +R D + N D++ Sbjct: 376 QWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPSVFNSDEERY 431 Query: 1998 KPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + + E E+ ER ++ + E+ R+R H++++ T R KS R Sbjct: 432 RYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 471 >gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens] Length = 594 Score = 70.5 bits (171), Expect = 2e-11 Identities = 63/222 (28%), Positives = 100/222 (45%), Gaps = 35/222 (15%) Query: 1820 PPNFPPQSMFGFPP-HLPPP-LLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASR 1877 PP FPP G PP HLPPP LPPP P++P P PG P + P ++ Sbjct: 357 PPFFPP----GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES-- 410 Query: 1878 YIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK 1937 G + Y + R + P+G + P G D+ K Sbjct: 411 --GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT--------SK 449 Query: 1938 EWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD 1997 +W+ + R + RDR +D+DR+R + +D+ER R +R D + N D++ Sbjct: 450 QWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPSVFNSDEERY 505 Query: 1998 KPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + + E E+ ER ++ + E+ R+R H++++ T R KS R Sbjct: 506 RYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 545 >gi|41350335 transcription elongation factor A (SII), 3 [Homo sapiens] Length = 348 Score = 69.3 bits (168), Expect = 4e-11 Identities = 55/214 (25%), Positives = 96/214 (44%), Gaps = 5/214 (2%) Query: 831 KRESGEGRNSSDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKA 890 K E GE R + ++ ++ P + P R + + + + +S+ + + Sbjct: 86 KGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTRRDSVDSKSSASSSPKRPS 145 Query: 891 SKPGTHEKQEMKKKKVEKGVLNVHPAASASKPSADQIR-QSVRHSLKDILMKRL-TDSNL 948 + K + + K L A+S + + SVR ++L L D + Sbjct: 146 VERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPCYLTGDSVRDKCVEMLSAALKADDDY 205 Query: 949 KVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPD 1008 K K+A++IE ++ + TD KY+N+ RS + NLKDP+N L + VL G ++ Sbjct: 206 KDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISAG 265 Query: 1009 HLIRMSPEELASKELAAWRRRENRHTIEMIEKEQ 1042 + +M+ EE+AS EL R N T E I + Q Sbjct: 266 LIAKMTAEEMASDEL---RELRNAMTQEAIREHQ 296 >gi|239757964 PREDICTED: hypothetical protein [Homo sapiens] Length = 290 Score = 68.9 bits (167), Expect = 5e-11 Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 11/146 (7%) Query: 1902 GRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKD 1956 GR+ ++ DR R + D QR RER EK+ E+E+ER R R R +K+ Sbjct: 140 GRERERDRDREKERERQTEKDRDGQRETETERERDRER-EKQKERETERDRDRQRDTEKE 198 Query: 1957 RDRKSREEGHKDKERARLSHGDRGTDGKASRDS---RNVDKKPDKPKSEDYEKDKEREKS 2013 R+R++ E +D++R + R TD + R++ R + D+ K D E+D++ E+ Sbjct: 199 RERQTDRE--RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256 Query: 2014 KHREGEKDRDRYHKDRDHTDRTKSKR 2039 K R+ E+ ++R K ++ R KR Sbjct: 257 KERKKERKKERKEKKKEEKRREDKKR 282 Score = 68.2 bits (165), Expect = 8e-11 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 23/160 (14%) Query: 1902 GRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ-------D 1954 GR Q+ R + G+ + D +R+R ++ E+E +R R+RDR + + Sbjct: 52 GRLGSQESPRSWGLGQAHKDAD-GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110 Query: 1955 KDRDRKSREEGHKDKER----ARLSHGDRGTDGKASRD-----SRNVDKKPD--KPKSED 2003 ++RDR+ + E +D+ER R DRG + + RD R +K D + + Sbjct: 111 RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170 Query: 2004 YEKDKEREKSKHREGEKDRDRY---HKDRD-HTDRTKSKR 2039 E+D+EREK K RE E+DRDR K+R+ TDR + ++ Sbjct: 171 RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ 210 Score = 65.9 bits (159), Expect = 4e-10 Identities = 43/154 (27%), Positives = 80/154 (51%), Gaps = 16/154 (10%) Query: 1897 HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRR----RDRS 1952 H D G Q++ DR R K +++R +R R EKE + +R ++ RDR Sbjct: 69 HKDADGDDRQRERDRV--REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126 Query: 1953 QDK------DRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDYE 2005 ++K +RDR E +D+E+ R ++ DG+ ++ R D++ +K K + E Sbjct: 127 REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186 Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +D++R++ +E E+ DR +RD +T+++R Sbjct: 187 RDRDRQRDTEKERERQTDR---ERDRQRKTQTER 217 Score = 61.2 bits (147), Expect = 1e-08 Identities = 42/158 (26%), Positives = 75/158 (47%), Gaps = 8/158 (5%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 ++ RR E+ + R+ Q +++R R K + D + ++E E+E + + Sbjct: 100 RERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK 159 Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007 RD ++ + +R+ E K KER DR D + R+ R D++ D+ + E+ Sbjct: 160 DRDGQRETETERERDREREKQKERETERDRDRQRDTEKERE-RQTDRERDRQRKTQTERQ 218 Query: 2008 K------EREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + ERE + RE ++DRDR K+RD K +R Sbjct: 219 RETDREGERETDRRRERQRDRDR-GKERDRERDRKEER 255 Score = 59.3 bits (142), Expect = 4e-08 Identities = 34/148 (22%), Positives = 80/148 (54%), Gaps = 3/148 (2%) Query: 1894 ERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE-KEWEQESERHRRRDRS 1952 + R D +++++ ++ NR + DR++ +RE+ + +E E++ R R RDR Sbjct: 90 KERDRDRKRDRERRRKEKETNRNR-DREKQTEIERDREREKQKGRERERDRGRERERDRD 148 Query: 1953 QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDYEKDKERE 2011 ++K+R+R++ ++ +E DR + + R++ R+ D++ D K + + D+ER+ Sbjct: 149 REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208 Query: 2012 KSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + + + E+ R+ + TDR + ++ Sbjct: 209 RQRKTQTERQRETDREGERETDRRRERQ 236 Score = 49.3 bits (116), Expect = 4e-05 Identities = 28/110 (25%), Positives = 56/110 (50%), Gaps = 2/110 (1%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH-EKEWEQESERHRRRDRSQDKDRDRKS 1961 R+ ++Q +R R + DRQR + +R +++ + ++ER R DR +++ DR+ Sbjct: 175 REREKQKERETERDR-DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR 233 Query: 1962 REEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKERE 2011 + +D+ + R DR + K R ++ +K K E +DK+R+ Sbjct: 234 ERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283 Score = 42.7 bits (99), Expect = 0.004 Identities = 32/134 (23%), Positives = 60/134 (44%), Gaps = 22/134 (16%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH---EKEWEQESE 1944 +D R +++ + +D+Q+ + DR+R +R+R E E E + Sbjct: 173 RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR 232 Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R R+RDR + K+RDR+ + + KER + ++K ++ + + Sbjct: 233 RERQRDRDRGKERDRERDRKEERKKERKK-------------------ERKKERKEKKKE 273 Query: 2005 EKDKEREKSKHREG 2018 EK +E +K K EG Sbjct: 274 EKRREDKKRKWGEG 287 Score = 33.1 bits (74), Expect = 2.8 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 10/93 (10%) Query: 1874 QASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGK-GDRQRFYSDSHHLKR 1932 Q R Q Q + R +R R+ ++Q DR +RGK DR+R ++ Sbjct: 202 QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR--DRGKERDRERD-------RK 252 Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEG 1965 E +KE ++E ++ R+ + ++K R+ K R+ G Sbjct: 253 EERKKERKKERKKERKEKKKEEKRREDKKRKWG 285 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 68.6 bits (166), Expect = 6e-11 Identities = 42/145 (28%), Positives = 77/145 (53%), Gaps = 15/145 (10%) Query: 1888 KDIRR---PERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944 KD RR P ++ S R+ + ++ K R++ + +K + EKE E+E E Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKEREREKE 404 Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R + ++R ++KDRD++ ++ KDKE+ D + R+ + +K DK K ++ Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEK----------DREREREKEH-EKDRDKEKEKEQ 453 Query: 2005 EKDKEREKSKHREGEKDRDRYHKDR 2029 +K+KEREK + +E ++ R + K R Sbjct: 454 DKEKEREKDRSKEIDEKRKKDKKSR 478 Score = 62.8 bits (151), Expect = 3e-09 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Query: 1914 NRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHK--DK 1969 N KG R R + S S + ++ Q R R +RS+ + +DR+ + HK K Sbjct: 301 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360 Query: 1970 ERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDR 2029 R R R +D+R K+ ++ K +D EK++EREK + +E E+ +++ Sbjct: 361 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420 Query: 2030 DHTDRTKSK 2038 DR K K Sbjct: 421 REKDREKDK 429 Score = 59.7 bits (143), Expect = 3e-08 Identities = 38/143 (26%), Positives = 73/143 (51%), Gaps = 14/143 (9%) Query: 1895 RRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ 1953 R H+ RQ D+++ P + R+R S S R++ + E+ E+ R +++ + Sbjct: 336 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395 Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013 +K+R+R+ E K+KER GK + +K +K K +D E+++E+E Sbjct: 396 EKEREREKERE--KEKER-----------GKNKDRDKEREKDREKDKEKDREREREKEHE 442 Query: 2014 KHREGEKDRDRYHKDRDHTDRTK 2036 K R+ EK++++ + DR+K Sbjct: 443 KDRDKEKEKEQDKEKEREKDRSK 465 Score = 58.5 bits (140), Expect = 6e-08 Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 21/147 (14%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE---------KEWEQESERHRRRDRSQ 1953 R + + +R K + + S SH+ R R + K+ + ER + R RS Sbjct: 313 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372 Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013 +D+ + +RE K KE+ R+ DR + R +K+ +K K KD+++E+ Sbjct: 373 SRDKRKDTRE---KIKEKERVKEKDREKE-------REREKEREKEKERGKNKDRDKERE 422 Query: 2014 KHREGEKDRDR-YHKDRDH-TDRTKSK 2038 K RE +K++DR ++++H DR K K Sbjct: 423 KDREKDKEKDREREREKEHEKDRDKEK 449 Score = 55.8 bits (133), Expect = 4e-07 Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 22/168 (13%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R E+ R +++ DR ++ K DR+R H R++ EKE EQ+ E+ R +D Sbjct: 405 REKEKERGKNKDRDKEREKDREKDKEK-DREREREKEHEKDRDK-EKEKEQDKEKEREKD 462 Query: 1951 RSQDKD----RDRKSR--EEGHKDKERARLSHGDR-----GTDGKASRDSRNVDKKPDK- 1998 RS++ D +D+KSR + R+R S +R + ++ R S+ + +K + Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522 Query: 1999 --PKSEDYEKDKEREK-----SKHREGEKDRDRYHKDRDHTDRTKSKR 2039 P+S + +KDK+REK S+ RE E+ D + K ++ Sbjct: 523 PSPRSRN-KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569 Score = 47.8 bits (112), Expect = 1e-04 Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 24/155 (15%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962 R+ +++ ++ RGK + D K +KE ++E ER + ++ +DK+++++ Sbjct: 399 REREKEREKEKERGKNKDR----DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454 Query: 1963 EEGHKDKERARLSHGDRGTDGK---------ASRDSRNVDKKPDKPK----------SED 2003 +E ++K+R++ R D K ASR SR+ ++ + + S+ Sbjct: 455 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 ++ R S +KD+ R K+RDH + + Sbjct: 515 IKRKSSRSPSPRSRNKKDKKR-EKERDHISERRER 548 Score = 45.8 bits (107), Expect = 4e-04 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%) Query: 1936 EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDK 1994 E E + +ER R RS + + R S + H ++R++ H R + SR R K Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSS-SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352 Query: 1995 KPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHT---DRTKSK 2038 P K +S+ E+ K R +S R+ KD K+++ DR K + Sbjct: 353 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 399 Score = 33.5 bits (75), Expect = 2.2 Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%) Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQ-RFYSDSHHLKRERHEKEWEQESE 1944 ++ + R+ +++ P + + R +R + R+ R S S + K S Sbjct: 466 EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 525 Query: 1945 RHR-RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003 R R ++D+ ++K+RD S + R S DR DGK ++K K ++ Sbjct: 526 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDR--DGK-----EKLEKNSTSLKEKE 578 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDR 2029 + K+ + SK + +KD R +++ Sbjct: 579 HNKEPDSSVSKEVD-DKDAPRTEENK 603 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 68.6 bits (166), Expect = 6e-11 Identities = 42/145 (28%), Positives = 77/145 (53%), Gaps = 15/145 (10%) Query: 1888 KDIRR---PERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944 KD RR P ++ S R+ + ++ K R++ + +K + EKE E+E E Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKEREREKE 288 Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R + ++R ++KDRD++ ++ KDKE+ D + R+ + +K DK K ++ Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEK----------DREREREKEH-EKDRDKEKEKEQ 337 Query: 2005 EKDKEREKSKHREGEKDRDRYHKDR 2029 +K+KEREK + +E ++ R + K R Sbjct: 338 DKEKEREKDRSKEIDEKRKKDKKSR 362 Score = 62.8 bits (151), Expect = 3e-09 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 4/129 (3%) Query: 1914 NRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHK--DK 1969 N KG R R + S S + ++ Q R R +RS+ + +DR+ + HK K Sbjct: 185 NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244 Query: 1970 ERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDR 2029 R R R +D+R K+ ++ K +D EK++EREK + +E E+ +++ Sbjct: 245 SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304 Query: 2030 DHTDRTKSK 2038 DR K K Sbjct: 305 REKDREKDK 313 Score = 59.7 bits (143), Expect = 3e-08 Identities = 38/143 (26%), Positives = 73/143 (51%), Gaps = 14/143 (9%) Query: 1895 RRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ 1953 R H+ RQ D+++ P + R+R S S R++ + E+ E+ R +++ + Sbjct: 220 RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279 Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013 +K+R+R+ E K+KER GK + +K +K K +D E+++E+E Sbjct: 280 EKEREREKERE--KEKER-----------GKNKDRDKEREKDREKDKEKDREREREKEHE 326 Query: 2014 KHREGEKDRDRYHKDRDHTDRTK 2036 K R+ EK++++ + DR+K Sbjct: 327 KDRDKEKEKEQDKEKEREKDRSK 349 Score = 58.5 bits (140), Expect = 6e-08 Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 21/147 (14%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE---------KEWEQESERHRRRDRSQ 1953 R + + +R K + + S SH+ R R + K+ + ER + R RS Sbjct: 197 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256 Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013 +D+ + +RE K KE+ R+ DR + R +K+ +K K KD+++E+ Sbjct: 257 SRDKRKDTRE---KIKEKERVKEKDREKE-------REREKEREKEKERGKNKDRDKERE 306 Query: 2014 KHREGEKDRDR-YHKDRDH-TDRTKSK 2038 K RE +K++DR ++++H DR K K Sbjct: 307 KDREKDKEKDREREREKEHEKDRDKEK 333 Score = 55.8 bits (133), Expect = 4e-07 Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 22/168 (13%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R E+ R +++ DR ++ K DR+R H R++ EKE EQ+ E+ R +D Sbjct: 289 REKEKERGKNKDRDKEREKDREKDKEK-DREREREKEHEKDRDK-EKEKEQDKEKEREKD 346 Query: 1951 RSQDKD----RDRKSR--EEGHKDKERARLSHGDR-----GTDGKASRDSRNVDKKPDK- 1998 RS++ D +D+KSR + R+R S +R + ++ R S+ + +K + Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406 Query: 1999 --PKSEDYEKDKEREK-----SKHREGEKDRDRYHKDRDHTDRTKSKR 2039 P+S + +KDK+REK S+ RE E+ D + K ++ Sbjct: 407 PSPRSRN-KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453 Score = 47.8 bits (112), Expect = 1e-04 Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 24/155 (15%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962 R+ +++ ++ RGK + D K +KE ++E ER + ++ +DK+++++ Sbjct: 283 REREKEREKEKERGKNKDR----DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338 Query: 1963 EEGHKDKERARLSHGDRGTDGK---------ASRDSRNVDKKPDKPK----------SED 2003 +E ++K+R++ R D K ASR SR+ ++ + + S+ Sbjct: 339 KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 ++ R S +KD+ R K+RDH + + Sbjct: 399 IKRKSSRSPSPRSRNKKDKKR-EKERDHISERRER 432 Score = 45.8 bits (107), Expect = 4e-04 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%) Query: 1936 EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDK 1994 E E + +ER R RS + + R S + H ++R++ H R + SR R K Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSS-SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 236 Query: 1995 KPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHT---DRTKSK 2038 P K +S+ E+ K R +S R+ KD K+++ DR K + Sbjct: 237 SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 283 Score = 33.5 bits (75), Expect = 2.2 Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%) Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQ-RFYSDSHHLKRERHEKEWEQESE 1944 ++ + R+ +++ P + + R +R + R+ R S S + K S Sbjct: 350 EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 409 Query: 1945 RHR-RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003 R R ++D+ ++K+RD S + R S DR DGK ++K K ++ Sbjct: 410 RSRNKKDKKREKERDHISERRERERSTSMRKSSNDR--DGK-----EKLEKNSTSLKEKE 462 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDR 2029 + K+ + SK + +KD R +++ Sbjct: 463 HNKEPDSSVSKEVD-DKDAPRTEENK 487 >gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens] Length = 588 Score = 67.4 bits (163), Expect = 1e-10 Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 36/231 (15%) Query: 1812 PPGFPFPGPPNFPPQSMFGFPP---HLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRM 1868 PP FP PP P F PP PPL+PPPG VP P PG P Sbjct: 342 PPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPIT----VPPPGFPPPPGAPPPS 397 Query: 1869 MGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSH 1928 + P ++ G + Y + R + P+G + P G D+ Sbjct: 398 LIPTIES----GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT- 441 Query: 1929 HLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988 K+W+ + R + RDR +D+DR+R + +D+ER R +R D + Sbjct: 442 -------SKQWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPS 490 Query: 1989 SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 N D++ + + E E+ ER ++ + E+ R+R H++++ T R KS R Sbjct: 491 VFNSDEERYRYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 539 Score = 58.2 bits (139), Expect = 8e-08 Identities = 62/272 (22%), Positives = 115/272 (42%), Gaps = 53/272 (19%) Query: 1788 SPRTSTNFSPMRPQQPNLQHLKSSPPGFPFPG------PPNFPPQSMFGFPPHLPPPLLP 1841 +P T P P P + ++PP P PG PP FPP PP PPP L Sbjct: 349 APPTHLPPPPFLPPPPTVS---TAPPLIPPPGIPITVPPPGFPP------PPGAPPPSLI 399 Query: 1842 P-------PGFGFAQNPMVPWPPVV--HLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRR 1892 P G+ P+ V HLPG + + ++ ++Y ++ R Sbjct: 400 PTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQW----DYYARREKDR 455 Query: 1893 PERRHSDPWGRQDQQQLDRPFNRGK-GDRQRFYSDSHHL-----KRERHEKEWEQESERH 1946 R D R+ + DR R + +R+R +S + + +R R+ + E+ ERH Sbjct: 456 DRERDRD---RERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 512 Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 R ++++ + RE H++KE R K+SR N ++ + + + + + Sbjct: 513 R-----ASREKEERHRERRHREKEETR---------HKSSRS--NSRRRHESEEGDSHRR 556 Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 K ++ + +EG++ +++ T+ T ++ Sbjct: 557 HKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588 >gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial [Homo sapiens] Length = 213 Score = 66.6 bits (161), Expect = 2e-10 Identities = 40/151 (26%), Positives = 78/151 (51%), Gaps = 7/151 (4%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-RHEKEWEQESERHRRR 1949 R ER R+ ++Q DR +G+RQR +RE E++ E+E++RH Sbjct: 50 RDRERNRERDRDREREKQTDR-----EGERQRERERDRDRQRETERERDKERETDRHTET 104 Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKE 2009 DR + K ++R+ +++E+ + +R TD + R+ ++ + E +D+ Sbjct: 105 DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164 Query: 2010 REKSKHREGEKDRDRYHKDRD-HTDRTKSKR 2039 RE+ + R+ E++R R K+R+ HTD + ++ Sbjct: 165 RERERERKRERERKRETKERERHTDMERERQ 195 Score = 62.0 bits (149), Expect = 6e-09 Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 20/148 (13%) Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951 + E RH+ +Q +R R + DR+R R + K ++ SER R+RDR Sbjct: 4 KTEGRHTHTETETMDRQRER---RRETDRER--------DRAKESKTEDRHSERDRQRDR 52 Query: 1952 SQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSED--YEKDK 2008 ++++RDR E D+E G+R + + RD R +++ DK + D E D+ Sbjct: 53 ERNRERDRDREREKQTDRE------GERQRERERDRDRQRETERERDKERETDRHTETDR 106 Query: 2009 EREKSKHREGEKDRDRYHKDRDHTDRTK 2036 ER+K K RE E+ RDR + + R + Sbjct: 107 ERQKQKEREMERVRDREREKQKEMGRER 134 Score = 60.1 bits (144), Expect = 2e-08 Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 9/139 (6%) Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962 R+ +++ DR +R K + ++ H +R+R +++ E+ ER R R+R + DR+ + + Sbjct: 21 RERRRETDRERDRAKESK----TEDRHSERDR-QRDRERNRERDRDREREKQTDREGERQ 75 Query: 1963 EEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE--KDKEREKSKHREGEK 2020 E +D++R R + +R + + R + D++ K K + E +D+EREK K E+ Sbjct: 76 RERERDRDRQRETERERDKERETDRHT-ETDRERQKQKEREMERVRDREREKQKEMGRER 134 Query: 2021 DRDRYHKDRDHTDRTKSKR 2039 DR DR+ + + +R Sbjct: 135 QTDR-ETDRERERQAERER 152 Score = 58.5 bits (140), Expect = 6e-08 Identities = 42/156 (26%), Positives = 82/156 (52%), Gaps = 7/156 (4%) Query: 1888 KDIRRPERRHSDPWG-RQDQQQLDRPFNRG---KGDRQRFYSDSHHLKRERHEKEWEQES 1943 +D R + +D G RQ +++ DR R + D++R +D H +K+ E+E Sbjct: 58 RDRDREREKQTDREGERQRERERDRDRQRETERERDKER-ETDRHTETDRERQKQKEREM 116 Query: 1944 ERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003 ER R R+R + K+ R+ + + D+ER R + +R T + + R+ +++ ++ K E Sbjct: 117 ERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERER-KRER 175 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 K + +E+ +H + E++R R DR + +S+R Sbjct: 176 ERKRETKERERHTDMERERQR-ETDRKRDRQRESER 210 Score = 55.8 bits (133), Expect = 4e-07 Identities = 34/136 (25%), Positives = 69/136 (50%), Gaps = 5/136 (3%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949 R +R+ R +++ DR + DR+R ++R R E+E ++E R R+ Sbjct: 80 RDRDRQRETERERDKERETDR---HTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136 Query: 1950 DRSQDKDRDRKSREEGHKDKERARLS-HGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDK 2008 DR D++R+R++ E +ER H +R + K R+ + K+ ++ + E+ + Sbjct: 137 DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196 Query: 2009 EREKSKHREGEKDRDR 2024 E ++ + R+ E +R+R Sbjct: 197 ETDRKRDRQRESERER 212 Score = 47.0 bits (110), Expect = 2e-04 Identities = 30/111 (27%), Positives = 58/111 (52%), Gaps = 12/111 (10%) Query: 1940 EQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG-DRGTDGKASRDSRNVDKKPDK 1998 E ++E ++ DR R+ R E ++++RA+ S DR ++ RD R +++ D+ Sbjct: 2 ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRD-RERNRERDR 60 Query: 1999 PKSEDYEKDKEREKSKHREGEKDRDR-YHKDRD---------HTDRTKSKR 2039 + + + D+E E+ + RE ++DR R ++RD TDR + K+ Sbjct: 61 DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111 Score = 45.1 bits (105), Expect = 7e-04 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 23/122 (18%) Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945 +++ +R ER GR ++Q DR +R +R+R RER ++ +E ER Sbjct: 115 EMERVRDREREKQKEMGR--ERQTDRETDR---ERERQAERERETGRERKTEDRHRERER 169 Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 R+R+R ++ R+ K RE H D ER R R D+K D+ + + E Sbjct: 170 ERKRER--ERKRETKERER-HTDMERER---------------QRETDRKRDRQRESERE 211 Query: 2006 KD 2007 +D Sbjct: 212 RD 213 >gi|239747891 PREDICTED: hypothetical protein [Homo sapiens] Length = 202 Score = 65.9 bits (159), Expect = 4e-10 Identities = 39/136 (28%), Positives = 74/136 (54%), Gaps = 11/136 (8%) Query: 1906 QQQLDRPFNRGKG-DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREE 1964 Q++ R +RGK +R+R R+R + + RHR+RDR +++DR +E Sbjct: 4 QRERKRETDRGKETERER--------DRQRERENQTERENRHRQRDRHRERDRQTDREKE 55 Query: 1965 GHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDR 2024 + KER R +R T+ + R R ++ ++ + D E+DK+R++ + RE +++R+R Sbjct: 56 RERQKERDRQRQRERETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114 Query: 2025 YHK-DRDHTDRTKSKR 2039 K R+ +T+ +R Sbjct: 115 NRKGGRERDKQTERER 130 Score = 63.5 bits (153), Expect = 2e-09 Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 36/171 (21%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH---------EKEWEQ 1941 R+ ER+ G++ +++ DR R + ++ H +R+RH EKE E+ Sbjct: 3 RQRERKRETDRGKETERERDRQRERENQTER----ENRHRQRDRHRERDRQTDREKERER 58 Query: 1942 ESER--------------HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASR 1987 + ER R+R+R + ++R R++ E KD++R R DR Sbjct: 59 QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR-------- 110 Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 +R ++K + + + E++++RE+ + R+ E++R R + + TDR + + Sbjct: 111 -NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160 Score = 58.5 bits (140), Expect = 6e-08 Identities = 42/169 (24%), Positives = 83/169 (49%), Gaps = 19/169 (11%) Query: 1882 QNFYQVKDIRRPERRHSD-PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE 1940 +N ++ +D R R +D R+ Q++ DR RQR +R+R E++ + Sbjct: 34 ENRHRQRDRHRERDRQTDREKERERQKERDR-------QRQRERETERETERQR-ERQRQ 85 Query: 1941 QESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPD 1997 +E +R R+R +D+DR+RK + ++++ R D+ T+ + R+ R +++ Sbjct: 86 RERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ 145 Query: 1998 KPKSEDYEKDKER-------EKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 + + E D+ER E+ K R+ E+ ++R K ++ R KR Sbjct: 146 RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194 Score = 51.2 bits (121), Expect = 1e-05 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 8/131 (6%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R ER+ R+ ++Q DR ++ DR R RER+ K +E ++ R+ Sbjct: 74 RETERQRERQRQRERKRQTDRERDK---DRDRERKRETDRNRERNRKGG-RERDKQTERE 129 Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD--KPKSEDYEKDK 2008 R ++++R R+ E + +ER R DR A R+ R ++K + K + E +++K Sbjct: 130 RDRERERQRQRERERQRQRERKR--ETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187 Query: 2009 EREKSKHREGE 2019 RE K + GE Sbjct: 188 RREDKKRKWGE 198 Score = 50.4 bits (119), Expect = 2e-05 Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 14/113 (12%) Query: 1940 EQESERHRRRDRSQD--KDRDRKSREEGHKDKE-----RARLSHGDRGTDGKASRD---- 1988 E++ ER R DR ++ ++RDR+ E ++E R R DR TD + R+ Sbjct: 2 ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61 Query: 1989 ---SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038 R +++ ++ E+ ++RE+ + + E+D+DR + + TDR + + Sbjct: 62 RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114 Score = 43.9 bits (102), Expect = 0.002 Identities = 20/93 (21%), Positives = 51/93 (54%), Gaps = 12/93 (12%) Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 R+R+R ++ DR +++ E + +ER + + R++R+ ++ D+ + D + Sbjct: 3 RQRERKRETDRGKETERERDRQRER----------ENQTERENRH--RQRDRHRERDRQT 50 Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 D+E+E+ + +E ++ R R + T+R + ++ Sbjct: 51 DREKERERQKERDRQRQRERETERETERQRERQ 83 Score = 39.3 bits (90), Expect = 0.040 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 14/103 (13%) Query: 1888 KDIRRPERRHSD-------PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER------ 1934 KD R +R +D GR+ +Q +R +R + +RQR +RER Sbjct: 98 KDRDRERKRETDRNRERNRKGGRERDKQTERERDRER-ERQRQRERERQRQRERKRETDR 156 Query: 1935 HEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG 1977 + W + ER + R + + K+R K +EE ++ ++ + G Sbjct: 157 ERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199 >gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens] Length = 1337 Score = 65.5 bits (158), Expect = 5e-10 Identities = 71/256 (27%), Positives = 103/256 (40%), Gaps = 45/256 (17%) Query: 1795 FSPMRPQQP--NLQHLKSSPPG---FPF----------PGPPNFPPQSMFGFPPHLPPPL 1839 F PM P P N + +PPG FPF P PP P Q + +PP Sbjct: 117 FPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHN 176 Query: 1840 LPPPGFGFAQNPMVPWPPVVHLPGQPQ-RMMGPL---SQASRYIGPQNFYQVKDIRRPER 1895 PPP F QN + P + P R + P S P+ D R + Sbjct: 177 FPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDH 236 Query: 1896 RHSDPWGRQDQQQ-LDRPFNRGKGDRQRF-------YSDSHHLKRER-HEKEWEQESERH 1946 H GR ++ + LDR DR+R Y R R +E+ E+E ERH Sbjct: 237 SH----GRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERH 292 Query: 1947 RRRD--------RSQDKDRDRKSREEGHKDKERARL-SHGDRGTDGKASRDSRNV----D 1993 R RD RS K+ R ++K+RAR DR +D ++S +N + Sbjct: 293 RHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKE 352 Query: 1994 KKPDKPKSEDYEKDKE 2009 K+P++ + E+++E Sbjct: 353 KEPEETMPDKNEEEEE 368 Score = 59.3 bits (142), Expect = 4e-08 Identities = 66/244 (27%), Positives = 90/244 (36%), Gaps = 61/244 (25%) Query: 1797 PMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPP-----PGFGF---- 1847 P+RP PN Q PFP PP FPP PP +P P PP PG G Sbjct: 97 PIRPPFPNHQMRH------PFPVPPCFPPM-----PPPMPCPNNPPVPGAPPGQGTFPFM 145 Query: 1848 ---AQNPMVPWPPVV-------HLPGQPQRMMGPLSQASRYIGPQNFY-QVKDIRRPERR 1896 P P PPV+ + PG P S S P +F + P R Sbjct: 146 MPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFR 205 Query: 1897 HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKD 1956 H P+ P R +R + Y D RH ERHR DR Sbjct: 206 HLPPYPLPKA-----PSERRSPERLKHYDD------HRHRDHSHGRGERHRSLDR----- 249 Query: 1957 RDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHR 2016 R+R + + R R + DRG + P + +S + +++ERE+ +HR Sbjct: 250 RERGRSPDRRRQDSRYRSDY-DRG-------------RTPSRHRSYERSRERERERHRHR 295 Query: 2017 EGEK 2020 + + Sbjct: 296 DNRR 299 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 63.5 bits (153), Expect = 2e-09 Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 29/209 (13%) Query: 1854 PWPPVVHLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPF 1913 PW P+V G ++ GP + + R +R QD+++ D+ Sbjct: 1168 PWRPLVKPGGWREKEKA----REESWGPPRESRPSEEREWDREKERDRDNQDREENDKDP 1223 Query: 1914 NRGKGDRQRFYSDSHHLKRERHEKEWE----QESERHRRRDRSQDKDRDRKSRE-EGHKD 1968 R + DR+R +R R E W +ES R R D+DRD + RE + +D Sbjct: 1224 ERER-DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRD 1282 Query: 1969 KERARLSHGDRGTDGKASRDSRNV--------DKKPDKPKSED---------YEKDKERE 2011 R DR G R R D+K D+ + D +D+ER+ Sbjct: 1283 LRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERD 1342 Query: 2012 KSKHREGEKDRD--RYHKDRDHTDRTKSK 2038 + + REGEK++ R KDR+ RTK++ Sbjct: 1343 RDREREGEKEKASWRAEKDRESLRRTKNE 1371 Score = 41.2 bits (95), Expect = 0.010 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 17/170 (10%) Query: 1882 QNFYQVK----DIRRPERRHSDPWGRQDQQQLDR--PFNRGKGDRQRFYSDSHHLK---- 1931 Q+ Y+ K + R E RH+ R+ Q++ +R + R K + ++ ++ LK Sbjct: 769 QSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE 828 Query: 1932 RERHEKEWEQES--ERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS 1989 RER E+ +E E R + ++ +R ++ RE +++ER R G + +DS Sbjct: 829 RERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDS 888 Query: 1990 RNVDKKPDKPKSEDYEKDKE-----REKSKHREGEKDRDRYHKDRDHTDR 2034 R D+ + + E D E EK R +D DR H+ + R Sbjct: 889 RWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPR 938 Score = 35.4 bits (80), Expect = 0.57 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 10/160 (6%) Query: 1889 DIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR- 1947 D R P R D G + DR RG D + + ++ + R E ++ R+ Sbjct: 1085 DDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMD 1144 Query: 1948 --RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 R R D DR + ++ R + G KA +S ++ + +++ Sbjct: 1145 DDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWD 1204 Query: 2006 KDKEREKSKH------REGEKDRDRYHKDRDHTDRTKSKR 2039 ++KER++ ++ E++RDR +D D DR + R Sbjct: 1205 REKERDRDNQDREENDKDPERERDR-ERDVDREDRFRRPR 1243 Score = 33.5 bits (75), Expect = 2.2 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 28/145 (19%) Query: 1889 DIRRPERRHSD---PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945 D R P R D PW D +L R R DR D R + E+ Sbjct: 1125 DDRIPRRGAEDDRGPWRNMDDDRLSR---RADDDRFPRRGDDSRPGPWRPLVKPGGWREK 1181 Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 + R+ S R+ + EE D+E+ R + ++D DK P++ E Sbjct: 1182 EKAREESWGPPRESRPSEEREWDREKER---------DRDNQDREENDKDPER------E 1226 Query: 2006 KDKEREKSKHREGEKDRDRYHKDRD 2030 +D+ER+ + DR+ + RD Sbjct: 1227 RDRERDVDR-------EDRFRRPRD 1244 Score = 33.1 bits (74), Expect = 2.8 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 16/154 (10%) Query: 1891 RRPERRHSDP-WGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949 R ERR D R+D + DR +G ++ +R EKEW + R Sbjct: 872 REEERRLGDSSLSRKDSRWGDRD---SEGTWRKGPEADSEWRRGPPEKEWRRGEGRD--E 926 Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKE 2009 DRS +D +R R +D+E + DR + D R + P++ + D + Sbjct: 927 DRSHRRDEERPRRLGDDEDREPSLRPDDDR-VPRRGMDDDRGPRRGPEEDRFSRRGADDD 985 Query: 2010 R--------EKSKHREGEKDRDRY-HKDRDHTDR 2034 R ++ R ++DR + H D D R Sbjct: 986 RPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPR 1019 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 63.2 bits (152), Expect = 3e-09 Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 9/156 (5%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQES----ERH 1946 R+ ERR + R+ +++ +R RGK ++++ +RER KE E++ E+ Sbjct: 36 RKKERREREK--RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93 Query: 1947 RRRDRSQDKDRDRK--SREEGHKDKER-ARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003 RR+ + + K R+RK R E K KER R + + K + + +K K + E Sbjct: 94 RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153 Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +++++R+K K E EK R+R K+R K +R Sbjct: 154 GKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189 Score = 59.3 bits (142), Expect = 4e-08 Identities = 34/140 (24%), Positives = 75/140 (53%), Gaps = 15/140 (10%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 ++ +R ERR + R+ +++ RG+ +R++ K+ER E+E E + R R Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKK--------KKERKERERENKQRRER 133 Query: 1948 RRDRSQDKDR---DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 +R + + K R ++ +E G ++++R + +R + R+ ++K ++ + E Sbjct: 134 KRKKRRKKKRRKERKREKERGKRERKRKKRKKEER----EKKRERNRKERKKERERKERR 189 Query: 2005 EKDKEREKSKHREGEKDRDR 2024 E+ KER+K + ++ E+ +DR Sbjct: 190 ERKKERKKERRKKKERKKDR 209 Score = 57.4 bits (137), Expect = 1e-07 Identities = 31/115 (26%), Positives = 66/115 (57%), Gaps = 7/115 (6%) Query: 1929 HLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988 H+ + ++E E++ ER R R ++++++RK RE G K+K++ + +RG + + R Sbjct: 24 HISKPCTQRESERKKERREREKRKREREKERK-RERGKKEKKKRK--KRERGKERERKRK 80 Query: 1989 SRNVDKK----PDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 R +K ++ K + +K +ER++ RE +K ++R ++R++ R + KR Sbjct: 81 EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135 Score = 55.5 bits (132), Expect = 5e-07 Identities = 36/153 (23%), Positives = 74/153 (48%), Gaps = 2/153 (1%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-H 1946 K R+ R + ++ +++ R R K R+R +++R +E +++ ER Sbjct: 63 KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122 Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 R R+ Q ++R RK R + + KER R + + R +KK ++ + E +K Sbjct: 123 RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE-RKK 181 Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 ++ER++ + R+ E+ ++R K DR ++ Sbjct: 182 ERERKERRERKKERKKERRKKKERKKDRKTDRQ 214 Score = 53.1 bits (126), Expect = 3e-06 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 14/151 (9%) Query: 1898 SDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQD-KD 1956 S P +++ ++ R K R+R KRER +KE ++ +R R ++R + K+ Sbjct: 26 SKPCTQRESERKKERREREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKE 81 Query: 1957 RDRKSREEGHKD--------KERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDK 2008 R+++ +E K+ K+R R G R K R R + K + + + K Sbjct: 82 REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141 Query: 2009 EREKSKHREGEK-DRDRYHKDRDHTDRTKSK 2038 +R K + RE E+ R+R K R +R K + Sbjct: 142 KRRKERKREKERGKRERKRKKRKKEEREKKR 172 Score = 51.6 bits (122), Expect = 8e-06 Identities = 31/102 (30%), Positives = 56/102 (54%), Gaps = 8/102 (7%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRR 1948 +R ER+ ++ +++ R RGK +R+R + KRER+ KE ++E ER R Sbjct: 129 QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188 Query: 1949 RDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSR 1990 R+R +++ ++R+ ++E KD++ DR TD + R R Sbjct: 189 RERKKERKKERRKKKERKKDRKT------DRQTDSQVFRPLR 224 Score = 43.5 bits (101), Expect = 0.002 Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 5/102 (4%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 ++ ER+ + +Q +++ R R K R+ + KRER K+ ++E ER ++R+ Sbjct: 116 KKKERKERERENKQRRER-KRKKRRKKKRRKERKREKERGKRERKRKKRKKE-EREKKRE 173 Query: 1951 RS---QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS 1989 R+ + K+R+RK R E K++++ R +R D K R + Sbjct: 174 RNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215 >gi|52426743 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 62.8 bits (151), Expect = 3e-09 Identities = 28/107 (26%), Positives = 58/107 (54%) Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNV 1992 ER +KE ++ ER + R+R +++ ++ REE ++KERAR + + ++ SR Sbjct: 245 ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304 Query: 1993 DKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 D++ + + + +ER +S+ R+ + R +R H R++ +R Sbjct: 305 DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351 Score = 55.1 bits (131), Expect = 7e-07 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 11/157 (7%) Query: 1887 VKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERH 1946 V++++ R+ ++ R ++ + ++ R + +++R + +RER + E+E E+ Sbjct: 227 VEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKER---EREREERERKRRREEEEREKE 282 Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 R RDR + K +SR R S + + + R SR+ D++ + +S D + Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSE 340 Query: 2007 DKEREKSKHREGEKDRDR-----YHKDRDHTDRTKSK 2038 K R +S+ R K RDR K RD KSK Sbjct: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377 Score = 55.1 bits (131), Expect = 7e-07 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 21/160 (13%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-- 1945 K P+R +Q++++ ++ R + +R+R KR R E+E E+E R Sbjct: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERER--------KRRREEEEREKERARDR 287 Query: 1946 -HRRRDRSQDKDRDRK-----SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999 R+R RS+ + R SR HK + R+R R D + SR S + ++ + Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRSRDRRRSR-SHDRSERKHRS 345 Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +S D + K R++ ++ K RDR ++D + K KR Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDR---EQDRKSKEKEKR 382 Score = 51.2 bits (121), Expect = 1e-05 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 6/138 (4%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-----RHEKEWEQESER 1945 R ER + R+++++ ++ R + R+R S S H R ++ ++ R Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320 Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDY 2004 RRR RS+D+ R R K + R+R + D K+ + S++ D++ D+ E Sbjct: 321 ERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380 Query: 2005 EKDKEREKSKHREGEKDR 2022 ++ + +KS + G +++ Sbjct: 381 KRGSDDKKSSVKSGSREK 398 Score = 44.3 bits (103), Expect = 0.001 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 16/143 (11%) Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERH 1946 R R+ S R + DR +R + R+R S S +R R E++ R Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK-HRS 345 Query: 1947 RRRDRSQDKDRDRKS---------REEGHKDKERARLSHGDRGTDGKA-SRDSRNVDKKP 1996 R RDR + K RDRKS RE+ K KE+ + D+ + K+ SR+ ++ D Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405 Query: 1997 DKPKSEDYEKDKEREKSKHREGE 2019 + +S+ + + EG+ Sbjct: 406 ESKESDTKNEVNGTSEDIKSEGD 428 Score = 33.5 bits (75), Expect = 2.2 Identities = 28/128 (21%), Positives = 53/128 (41%), Gaps = 10/128 (7%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R + + S R+ + DR +R +R + +R ++ + R + RD Sbjct: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369 Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK-----SEDYE 2005 R Q DR K +E+ D +++ + G R K S D+ K+ D SED + Sbjct: 370 REQ--DRKSKEKEKRGSDDKKSSVKSGSR---EKQSEDTNTESKESDTKNEVNGTSEDIK 424 Query: 2006 KDKEREKS 2013 + + + + Sbjct: 425 SEGDTQSN 432 >gi|19923485 cisplatin resistance-associated overexpressed protein [Homo sapiens] Length = 432 Score = 62.8 bits (151), Expect = 3e-09 Identities = 28/107 (26%), Positives = 58/107 (54%) Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNV 1992 ER +KE ++ ER + R+R +++ ++ REE ++KERAR + + ++ SR Sbjct: 245 ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304 Query: 1993 DKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 D++ + + + +ER +S+ R+ + R +R H R++ +R Sbjct: 305 DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351 Score = 55.1 bits (131), Expect = 7e-07 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 11/157 (7%) Query: 1887 VKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERH 1946 V++++ R+ ++ R ++ + ++ R + +++R + +RER + E+E E+ Sbjct: 227 VEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKER---EREREERERKRRREEEEREKE 282 Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006 R RDR + K +SR R S + + + R SR+ D++ + +S D + Sbjct: 283 RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSE 340 Query: 2007 DKEREKSKHREGEKDRDR-----YHKDRDHTDRTKSK 2038 K R +S+ R K RDR K RD KSK Sbjct: 341 RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377 Score = 55.1 bits (131), Expect = 7e-07 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 21/160 (13%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-- 1945 K P+R +Q++++ ++ R + +R+R KR R E+E E+E R Sbjct: 236 KRTEEPDRDERLKKEKQEREEREKEREREREERER--------KRRREEEEREKERARDR 287 Query: 1946 -HRRRDRSQDKDRDRK-----SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999 R+R RS+ + R SR HK + R+R R D + SR S + ++ + Sbjct: 288 ERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRSRDRRRSR-SHDRSERKHRS 345 Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 +S D + K R++ ++ K RDR ++D + K KR Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDR---EQDRKSKEKEKR 382 Score = 51.2 bits (121), Expect = 1e-05 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 6/138 (4%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-----RHEKEWEQESER 1945 R ER + R+++++ ++ R + R+R S S H R ++ ++ R Sbjct: 261 REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320 Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDY 2004 RRR RS+D+ R R K + R+R + D K+ + S++ D++ D+ E Sbjct: 321 ERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380 Query: 2005 EKDKEREKSKHREGEKDR 2022 ++ + +KS + G +++ Sbjct: 381 KRGSDDKKSSVKSGSREK 398 Score = 44.3 bits (103), Expect = 0.001 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 16/143 (11%) Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERH 1946 R R+ S R + DR +R + R+R S S +R R E++ R Sbjct: 287 RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK-HRS 345 Query: 1947 RRRDRSQDKDRDRKS---------REEGHKDKERARLSHGDRGTDGKA-SRDSRNVDKKP 1996 R RDR + K RDRKS RE+ K KE+ + D+ + K+ SR+ ++ D Sbjct: 346 RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405 Query: 1997 DKPKSEDYEKDKEREKSKHREGE 2019 + +S+ + + EG+ Sbjct: 406 ESKESDTKNEVNGTSEDIKSEGD 428 Score = 33.5 bits (75), Expect = 2.2 Identities = 28/128 (21%), Positives = 53/128 (41%), Gaps = 10/128 (7%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950 R + + S R+ + DR +R +R + +R ++ + R + RD Sbjct: 310 RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369 Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK-----SEDYE 2005 R Q DR K +E+ D +++ + G R K S D+ K+ D SED + Sbjct: 370 REQ--DRKSKEKEKRGSDDKKSSVKSGSR---EKQSEDTNTESKESDTKNEVNGTSEDIK 424 Query: 2006 KDKEREKS 2013 + + + + Sbjct: 425 SEGDTQSN 432 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 62.4 bits (150), Expect = 4e-09 Identities = 43/159 (27%), Positives = 84/159 (52%), Gaps = 12/159 (7%) Query: 1889 DIRRPERR-HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE---QESE 1944 +IR ER + G+++++ + R + R+R +R + EK+ E +E E Sbjct: 37 EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96 Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004 R +RR ++K+ + K + + + KER R S G + + + + ++K + K E+ Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTS--KEGKERERKEERKREERKERERKKEER 154 Query: 2005 EKDKEREKSKHRE----GEKDRDRYHKDRDHTDRTKSKR 2039 EK++ER++ K RE GEK+ +R K+++ +R K +R Sbjct: 155 EKERERKERKKRERKQVGEKEEER--KEKERKERKKRER 191 Score = 60.1 bits (144), Expect = 2e-08 Identities = 43/158 (27%), Positives = 82/158 (51%), Gaps = 15/158 (9%) Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGK----GDRQRFYSDSHHLKRERHEKEWEQESERH 1946 R+ ERR + R+ +++ +R RGK G+R++ + K+ R EKE +E E Sbjct: 59 RKKERREREK--RKREREKERKRERGKKEKKGERKK---EERERKKRRREKE-NKEGEEK 112 Query: 1947 RRRDRSQDKDRDRKSRE--EGHKDKERARLSHGDR---GTDGKASRDSRNVDKKPDKPKS 2001 +R + + K+R R S+E E + +ER R +R + + R+ + K+ K Sbjct: 113 EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172 Query: 2002 EDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 E E+ KE+E+ + ++ E++R K+R+ +R + K+ Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210 Score = 59.3 bits (142), Expect = 4e-08 Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 12/154 (7%) Query: 1898 SDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDK-- 1955 + P + + ++ +R K ++ S+ +RER +++ E+E ER R R + + K Sbjct: 30 TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE 89 Query: 1956 ----DRDRKSR------EEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005 +R+RK R +EG + ++R + +RG K ++ +++ + + E Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149 Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 K +EREK + R+ K R+R +R + +R Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKER 183 Score = 54.3 bits (129), Expect = 1e-06 Identities = 36/162 (22%), Positives = 79/162 (48%), Gaps = 18/162 (11%) Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947 K+ R ++R + ++ +++ R + K ++R + +RER E+ +E + Sbjct: 92 KEERERKKRRREKENKEGEEKEKR---KKKEKKERGRTSKEGKERERKEERKREERKERE 148 Query: 1948 RRDRSQDKDRDRKSREE------GHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKS 2001 R+ ++K+R+RK R++ G K++ER +R R+ ++K ++ + Sbjct: 149 RKKEEREKERERKERKKRERKQVGEKEEERKEKERKER-----KKRERNRKERKKERERK 203 Query: 2002 EDYEKDKER----EKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039 E E+ KER E+ K R+ ++ + K+R +R + K+ Sbjct: 204 ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245 Score = 32.7 bits (73), Expect = 3.7 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 1/85 (1%) Query: 1027 RRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLE 1086 + RE+ E E+E+R+ ER K +G+ E + + +E+E +E + E Sbjct: 53 KERESERKKERREREKRKREREKERK-RERGKKEKKGERKKEERERKKRRREKENKEGEE 111 Query: 1087 KPEGSEKQKEEVDSMSKDTTSQHRQ 1111 K + +K+K+E SK+ + R+ Sbjct: 112 KEKRKKKEKKERGRTSKEGKERERK 136 >gi|38505156 transcription elongation factor A protein 2 isoform b [Homo sapiens] Length = 272 Score = 62.0 bits (149), Expect = 6e-09 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Query: 930 SVRHSLKDILMKRL-TDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNL 988 +VR+ +++L L TD + +++ +IE+ +F +TD KYKN+ RS + NL Sbjct: 110 AVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNL 169 Query: 989 KDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035 KD KN L + VL G +TP + M+ EE+AS EL R+ + I Sbjct: 170 KDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAI 216 >gi|4507385 transcription elongation factor A protein 2 isoform a [Homo sapiens] Length = 299 Score = 62.0 bits (149), Expect = 6e-09 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%) Query: 930 SVRHSLKDILMKRL-TDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNL 988 +VR+ +++L L TD + +++ +IE+ +F +TD KYKN+ RS + NL Sbjct: 137 AVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNL 196 Query: 989 KDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035 KD KN L + VL G +TP + M+ EE+AS EL R+ + I Sbjct: 197 KDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAI 243 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.361 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 85,393,349 Number of Sequences: 37866 Number of extensions: 4533125 Number of successful extensions: 32919 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 305 Number of HSP's successfully gapped in prelim test: 878 Number of HSP's that attempted gapping in prelim test: 19704 Number of HSP's gapped (non-prelim): 8766 length of query: 2039 length of database: 18,247,518 effective HSP length: 118 effective length of query: 1921 effective length of database: 13,779,330 effective search space: 26470092930 effective search space used: 26470092930 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.