Guide to the Human Genome
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Search of human proteins with 7662018

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662018 PHD finger protein 3 [Homo sapiens]
         (2039 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662018 PHD finger protein 3 [Homo sapiens]                       4109   0.0  
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]      235   4e-61
gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]      199   2e-50
gi|47271475 SPOC domain containing 1 [Homo sapiens]                   193   2e-48
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        84   1e-15
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                81   9e-15
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    74   1e-12
gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo ...    74   2e-12
gi|5803191 transcription elongation factor A 1 isoform 1 [Homo s...    74   2e-12
gi|45439355 transcription elongation factor A 1 isoform 2 [Homo ...    74   2e-12
gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]            73   3e-12
gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]       72   7e-12
gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]       72   7e-12
gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]                      70   2e-11
gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]                       70   2e-11
gi|41350335 transcription elongation factor A (SII), 3 [Homo sap...    69   4e-11
gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]            69   5e-11
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    69   6e-11
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    69   6e-11
gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]                      67   1e-10
gi|239747174 PREDICTED: hypothetical protein XP_002343931, parti...    67   2e-10
gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]            66   4e-10
gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]        65   5e-10
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    64   2e-09
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            63   3e-09
gi|52426743 cisplatin resistance-associated overexpressed protei...    63   3e-09
gi|19923485 cisplatin resistance-associated overexpressed protei...    63   3e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            62   4e-09
gi|38505156 transcription elongation factor A protein 2 isoform ...    62   6e-09
gi|4507385 transcription elongation factor A protein 2 isoform a...    62   6e-09

>gi|7662018 PHD finger protein 3 [Homo sapiens]
          Length = 2039

 Score = 4109 bits (10656), Expect = 0.0
 Identities = 2039/2039 (100%), Positives = 2039/2039 (100%)

Query: 1    MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 60
            MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS
Sbjct: 1    MDIVDTFNHLIPTEHLDDALFLGSNLENEVCEDFSASQNVLEDSLKNMLSDKDPMLGSAS 60

Query: 61   NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 120
            NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE
Sbjct: 61   NQFCLPVLDSNDPNFQMPCSTVVGLDDIMDEGVVKESGNDTIDEEELILPNRNLRDKVEE 120

Query: 121  NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 180
            NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ
Sbjct: 121  NSVRSPRKSPRLMAQEQVRSLRQSTIAKRSNAAPLSNTKKASGKTVSTAKAGVKQPERSQ 180

Query: 181  VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 240
            VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC
Sbjct: 181  VKEEVCMSLKPEYHKENRRCSRNSGQIEVVPEVSVSSSHSSVSSCLEMKDEDGLDSKHKC 240

Query: 241  NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 300
            NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI
Sbjct: 241  NNPGEIDVPSHELNCSLLSETCVTIGEKKNEALMECKAKPVGSPLFKFSDKEEHEQNDSI 300

Query: 301  SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 360
            SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL
Sbjct: 301  SGKTGETVVEEMIATRKVEQDSKETVKLSHEDDHILEDAGSSDISSDAACTNPNKTENSL 360

Query: 361  VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 420
            VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN
Sbjct: 361  VGLPSCVDEVTECNLELKDTMGIADKTENTLERNKIEPLGYCEDAESNRQLESTEFNKSN 420

Query: 421  LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 480
            LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY
Sbjct: 421  LEVVDTSTFGPESNILENAICDVPDQNSKQLNAIESTKIESHETANLQDDRNSQSSSVSY 480

Query: 481  LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 540
            LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN
Sbjct: 481  LESKSVKSKHTKPVIHSKQNMTTDAPKKIVAAKYEVIHSKTKVNVKSVKRNTDVPESQQN 540

Query: 541  FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 600
            FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS
Sbjct: 541  FHRPVKVRKKQIDKEPKIQSCNSGVKSVKNQAHSVLKKTLQDQTLVQIFKPLTHSLSDKS 600

Query: 601  HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 660
            HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK
Sbjct: 601  HAHPGCLKEPHHPAQTGHVSHSSQKQCHKPQQQAPAMKTNSHVKEELEHPGVEHFKEEDK 660

Query: 661  LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 720
            LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC
Sbjct: 661  LKLKKPEKNLQPRQRRSSKSFSLDEPPLFIPDNIATIRREGSDHSSSFESKYMWTPSKQC 720

Query: 721  GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL 780
            GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL
Sbjct: 721  GFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCCAEEDKKTEIL 780

Query: 781  DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS 840
            DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS
Sbjct: 781  DPDTLENQATVEFHSGDKTMECEKLGLSKHTTNDRTKYIDDTVKHKVKILKRESGEGRNS 840

Query: 841  SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE 900
            SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE
Sbjct: 841  SDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKASKPGTHEKQE 900

Query: 901  MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT 960
            MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT
Sbjct: 901  MKKKKVEKGVLNVHPAASASKPSADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVAT 960

Query: 961  KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS 1020
            KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS
Sbjct: 961  KIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELAS 1020

Query: 1021 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA 1080
            KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA
Sbjct: 1021 KELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPA 1080

Query: 1081 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV 1140
            ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV
Sbjct: 1081 ANKSLEKPEGSEKQKEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVV 1140

Query: 1141 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST 1200
            VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST
Sbjct: 1141 VGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKSTFSPAPRPEMPGTVEVEST 1200

Query: 1201 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK 1260
            FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK
Sbjct: 1201 FLARLNFIWKGFINMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEK 1260

Query: 1261 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD 1320
            IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD
Sbjct: 1261 IKASGTKEICVVRFTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATD 1320

Query: 1321 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK 1380
            KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK
Sbjct: 1321 KIPHPLVPFDGPGLELHRPNLLLGLIIRQKLKRQHSACASTSHIAETPESAPPIALPPDK 1380

Query: 1381 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL 1440
            KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL
Sbjct: 1381 KSKIEVSTEEAPEEENDFFNSFTTVLHKQRNKPQQNLQEDLPTAVEPLMEVTKQEPPKPL 1440

Query: 1441 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN 1500
            RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN
Sbjct: 1441 RFLPGVLIGWENQPTTLELANKPLPVDDILQSLLGTTGQVYDQAQSVMEQNTVKEIPFLN 1500

Query: 1501 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL 1560
            EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL
Sbjct: 1501 EQTNSKIEKTDNVEVTDGENKEIKVKVDNISESTDKSAEIETSVVGSSSISAGSLTSLSL 1560

Query: 1561 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV 1620
            RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV
Sbjct: 1561 RGKPPDVSTEAFLTNLSIQSKQEETVESKEKTLKRQLQEDQENNLQDNQTSNSSPCRSNV 1620

Query: 1621 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM 1680
            GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM
Sbjct: 1621 GKGNIDGNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCRNGEKHM 1680

Query: 1681 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ 1740
            LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ
Sbjct: 1681 LPGLSHNKEHLTEQINVEEKLCSAEKNSCVQQSDNLKVAQNSPSVENIQTSQAEQAKPLQ 1740

Query: 1741 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP 1800
            EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP
Sbjct: 1741 EDILMQNIETVHPFRRGSAVATSHFEVGNTCPSEFPSKSITFTSRSTSPRTSTNFSPMRP 1800

Query: 1801 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH 1860
            QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH
Sbjct: 1801 QQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVH 1860

Query: 1861 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR 1920
            LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR
Sbjct: 1861 LPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDR 1920

Query: 1921 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG 1980
            QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG
Sbjct: 1921 QRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG 1980

Query: 1981 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR
Sbjct: 1981 TDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score =  235 bits (599), Expect = 4e-61
 Identities = 255/952 (26%), Positives = 388/952 (40%), Gaps = 179/952 (18%)

Query: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181
            P++DLSP        V   V V+ +       S   A++S ++   S    E +Q+ PK 
Sbjct: 942  PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001

Query: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213
                             SP PR    P  P     ES          FL+RL+ IWKGFI
Sbjct: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061

Query: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273
            NM SVAKFVTKAYPVSG  +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R
Sbjct: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121

Query: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333
            F P TEE++++Y  L++YFSSR R+GV ANN + VKD+YLIPL A D +P  L+PF+GPG
Sbjct: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181

Query: 1334 LELHRPNLLLGLIIRQKLKR---------------------------------------- 1353
            LE  RPN++LGL+I QK+KR                                        
Sbjct: 1182 LESPRPNIILGLVICQKIKRPANSGELDKMDEKRTRLQPEEADVPAYPKVATVPQSEKKP 1241

Query: 1354 -QHSACASTSHIAETPESAPPIALPPDKKSKIEVSTEEAPEEENDFFNSFTTVLHKQRNK 1412
             ++  C++ + ++ TP  +PP   P  +   ++V +   P   +    + T         
Sbjct: 1242 SKYPLCSADAAVSTTPPGSPPPPPPLPEPPVLKVLSSLKPAAPSPATAATTAAAASTAAS 1301

Query: 1413 PQQNLQEDLPTAVEPLMEV---TKQEPPKPLRFLPGVLIGWENQPTTLELANKPLPVDDI 1469
               +      + +E +++     K+      R  PG   G   +P T   A   +P   +
Sbjct: 1302 STASSASKTASPLEHILQTLFGKKKSFDPSAREPPGSTAGLPQEPKT--TAEDGVPAPPL 1359

Query: 1470 LQSLLGTTGQVYDQAQSVMEQNTVKEIPFLNEQTNSKIEKTDNVEVTDGENKEIKVKVDN 1529
            L  ++   GQ + + +++ E+    + P+  E+        D   V  G   E++   + 
Sbjct: 1360 LDPIVQQFGQ-FSKDKALEEEE--DDRPYDPEEEYDPERAFDTQLVERGRRHEVERAPEA 1416

Query: 1530 ISESTDKSA---EIETSVVGSSSISAGSLTSLSLRG-------KPPDVSTEAFLTNLSIQ 1579
             +   ++ A   E ET ++  + ++   L +            +P +    A   +L  Q
Sbjct: 1417 AAAEREEVAYDPEDET-ILEEAKVTVDDLPNRMCADVRRNSVERPAEPVAGAATPSLVEQ 1475

Query: 1580 SKQEETVESKEKTLKRQLQEDQENNLQD-------------NQTSNSSPCRSNVGKGNID 1626
             K  E +  + +  KRQL+E +E   Q              +    S P +S++ K  + 
Sbjct: 1476 QKMLEELNKQIEEQKRQLEEQEEALRQQRAAVGVSMAHFSVSDALMSPPPKSSLPKAELF 1535

Query: 1627 GNVSCSENLVANTARSPQFINLKRDPRQAAGRSQPVTTSESKDGDSCR---NGEKHMLPG 1683
                 S +  A+   + Q  N  RDPRQA  R     T E +     R    G +  LP 
Sbjct: 1536 QQEQQSADKPASLPPASQASN-HRDPRQA--RRLAAETGEGEGEPLSRLSARGAQGALPE 1592

Query: 1684 LSHNKEHLTEQINV---EEK------LCSAEKNSCVQQSDNLKVAQNSPS-VENIQTSQA 1733
               ++  L  Q  +   EEK        S EK     + D  K      +    +  S A
Sbjct: 1593 RDASRGGLVGQAPMPVPEEKEPASSPWASGEKPPAGSEQDGWKAEPGEGTRPATVGDSSA 1652

Query: 1734 EQAK----------PLQEDILMQNIETVHPF------RRGSAVATSHFEVGNTCPSEFPS 1777
              A+           LQ    +Q+     PF       +  A+ ++ +E      S   S
Sbjct: 1653 RPARRVLLPTPPCGALQPGFPLQHDGERDPFTCPGFASQDKALGSAQYEDPRNLHSAGRS 1712

Query: 1778 KS---ITFTSRSTSPRTSTNFSPMRP-------QQPNLQHLKSSPP---------GFPFP 1818
             S    T   R    R     +P+ P        QP  Q  +   P         G  FP
Sbjct: 1713 SSPAGETEGDREPQARPGEGTAPLPPPGQKVGGSQPPFQGQREPGPHALGMSGLHGPNFP 1772

Query: 1819 GP----PNFPPQSMFGFPPHLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQ 1874
            GP    P FP +++        P   PP  FG  + P+       H P       GP   
Sbjct: 1773 GPRGPAPPFPEENIASNDGPRGP---PPARFGAQKGPIPSLFSGQHGPPPYGDSRGPSPS 1829

Query: 1875 ---ASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRF 1923
                 R + P  F + K          DP G + + Q D P+N   G   +F
Sbjct: 1830 YLGGPRGVAPSQFEERK----------DPHGEKREFQ-DAPYNEVTGAPAQF 1870



 Score =  177 bits (449), Expect = 9e-44
 Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%)

Query: 916  AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974
            +A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E +  K+A  IEKE+F+ F+ TD
Sbjct: 660  SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718

Query: 975  AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034
             +YK+KYRS+MFNLKDPKN  LF +VL+ E++   L+R+ PEEL SKEL+ W+ R  R  
Sbjct: 719  NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778

Query: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094
            +E   K   E ++   T    +   ++E   P+ + E   E       KS      +   
Sbjct: 779  MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829

Query: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149
             +   SM KDTTSQHR HLFDLNCKIC G++    D+ +PKK K+   V +     KH  
Sbjct: 830  LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889

Query: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187
            +  +   D+          E   E   ES        T+ P P
Sbjct: 890  SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 75/278 (26%), Positives = 116/278 (41%), Gaps = 34/278 (12%)

Query: 1772 PSEFPSKSITFTSRSTSPRTST--NFSPMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMF 1829
            P +F  + +    R T+ R      F  +R   P  +  + +P  F F G     PQ M 
Sbjct: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGSAPFSEKNEQTPSRFHFQGQA---PQVMK 2020

Query: 1830 GFP-PHLPPPLLPPPGFGFAQNPMVPW----PPVV---HLPGQPQRMMGPLSQASRYIGP 1881
              P P L  P  PP      Q+    W    PP       PGQ     G  + A    G 
Sbjct: 2021 PGPRPLLELPSHPP------QHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFREGK 2074

Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQ 1941
             + Y+ +     +R   D   ++   +      R   DR+R      +  RER   +W++
Sbjct: 2075 GHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRER---DWDR 2131

Query: 1942 ESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPK 2000
              E  R RD+   +D DR      ++D+ER      DRG +   SR+ SRN +++ D+ +
Sbjct: 2132 PREWDRHRDKDSSRDWDRNRERSANRDRER----EADRGKEWDRSRERSRNRERERDRRR 2187

Query: 2001 SEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
              D  + +ER++ K R+ E+ RDR        DR+KSK
Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDR-------KDRSKSK 2218



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%)

Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770
           + P+     C++PH NRFM+ C RC++WFHGDCVG+S ++ + +    ++Y+C  C    
Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323

Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822
            +++  +E  D      Q   ++  GD    +C  +G + + ++ D+       K  + +
Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377

Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867
            K K+KI +         +  G G       +S  C ++ I K   A ++ +      + 
Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437

Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916
             +EK +  P++ +   C    G K S        E K+  V+K V        L    A
Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497

Query: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961
             +S PS       + ++     +    L+ + T  + +  E+ AA  A+K
Sbjct: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548



 Score = 61.6 bits (148), Expect = 7e-09
 Identities = 65/243 (26%), Positives = 92/243 (37%), Gaps = 31/243 (12%)

Query: 1790 RTSTNFSPMRPQQPNLQHLKSSPPGFPFPGP------PNFPPQSMFG-FPPHLPPPLLPP 1842
            R S  FS    Q P+  H +   P    PGP      P+ PPQ     +    PP  L  
Sbjct: 1993 RGSAPFSEKNEQTPSRFHFQGQAPQVMKPGPRPLLELPSHPPQHRKDRWEEAGPPSALSS 2052

Query: 1843 PGFGFAQNPMVPWPPVVHLPGQPQRMMGPL---SQASRY-IGPQNFY--------QVKDI 1890
               G        W       G+            Q  R+ +GP+           +  + 
Sbjct: 2053 SAPGQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASED 2112

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKG-------DRQRFYSDSHHLKRERHE-KEWEQE 1942
            RR ER     W R+      R ++R +        DR R  S +   +RE    KEW++ 
Sbjct: 2113 RRRERERGRNWSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEWDRS 2172

Query: 1943 SERHRRRDRSQD--KDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK 2000
             ER R R+R +D  +DRDR    E  +DK R R    DR    K+   +R  D KP+  +
Sbjct: 2173 RERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESAR--DPKPEASR 2230

Query: 2001 SED 2003
            + D
Sbjct: 2231 ASD 2233



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 72/318 (22%), Positives = 116/318 (36%), Gaps = 66/318 (20%)

Query: 1768 GNTCPSEFPSKSITFTSRSTSPRTS--TNFSPMRPQQPN-LQHLKSSPPGFPFPGPPNFP 1824
            G   PS+F  +          PR    + F   R   PN  +  +   P F  PGP    
Sbjct: 1905 GGPPPSQFGGQRGPPPGHFVGPRGPHPSQFETARGPHPNQFEGPRGQAPNF-MPGPRGIQ 1963

Query: 1825 PQSMFGFPPHLPPPLL-----PPPGFGFAQNPMVPW-------PPVVHLPGQPQRMMGPL 1872
            PQ       H PP         P  FG  +    P+       P   H  GQ  ++M P 
Sbjct: 1964 PQQFEDQRVHSPPRFTNQRAPAPLQFGGLRGS-APFSEKNEQTPSRFHFQGQAPQVMKP- 2021

Query: 1873 SQASRYIGPQNFYQVKDIRRPERRHSDPWGRQ-----------------DQQQLDRPFNR 1915
                   GP+   ++     P +   D W                    D Q     F  
Sbjct: 2022 -------GPRPLLELPS--HPPQHRKDRWEEAGPPSALSSSAPGQGPEADGQWASADFRE 2072

Query: 1916 GKG-----------DRQRFYSDSHHLKRERHEKEWEQESERHRRRDR----SQDKDRDRK 1960
            GKG            R+RF         E  + +     +R R R+R    S+++D DR 
Sbjct: 2073 GKGHEYRNQTFEGRQRERFDVGPKEKPLEEPDAQGRASEDRRRERERGRNWSRERDWDRP 2132

Query: 1961 SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEK 2020
               + H+DK+ +R    DR  +  A+RD     ++ +  + +++++ +ER +++ RE ++
Sbjct: 2133 REWDRHRDKDSSR--DWDRNRERSANRD-----REREADRGKEWDRSRERSRNRERERDR 2185

Query: 2021 DRDRYHKDRDHTDRTKSK 2038
             RDR        DR K++
Sbjct: 2186 RRDRDRSRSRERDRDKAR 2203


>gi|71044477 death inducer-obliterator 1 isoform b [Homo sapiens]
          Length = 1189

 Score =  199 bits (507), Expect = 2e-50
 Identities = 111/240 (46%), Positives = 147/240 (61%), Gaps = 34/240 (14%)

Query: 1128 PVDDLSP------KKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESPKS 1181
            P++DLSP        V   V V+ +       S   A++S ++   S    E +Q+ PK 
Sbjct: 942  PLEDLSPCPASCGSGVVTTVTVSGRDPRTAPSSSCTAVASAASRPDSTHMVEARQDVPKP 1001

Query: 1182 TF---------------SPAPR----PEMPGTVEVEST---------FLARLNFIWKGFI 1213
                             SP PR    P  P     ES          FL+RL+ IWKGFI
Sbjct: 1002 VLTSVMVPKSILAKPSSSPDPRYLSVPPSPNISTSESRSPPEGDTTLFLSRLSTIWKGFI 1061

Query: 1214 NMPSVAKFVTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVR 1273
            NM SVAKFVTKAYPVSG  +YL+EDLPD+I +GGRI+P+TVWDYV K+K+S +KE+C++R
Sbjct: 1062 NMQSVAKFVTKAYPVSGCFDYLSEDLPDTIHIGGRIAPKTVWDYVGKLKSSVSKELCLIR 1121

Query: 1274 FTPVTEEDQISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPG 1333
            F P TEE++++Y  L++YFSSR R+GV ANN + VKD+YLIPL A D +P  L+PF+GPG
Sbjct: 1122 FHPATEEEEVAYISLYSYFSSRGRFGVVANNNRHVKDLYLIPLSAQDPVPSKLLPFEGPG 1181



 Score =  177 bits (449), Expect = 9e-44
 Identities = 109/283 (38%), Positives = 156/283 (55%), Gaps = 21/283 (7%)

Query: 916  AASASKPSADQIRQSVRHSLKDILMKRLTDSN-LKVPEEKAAKVATKIEKELFSFFRDTD 974
            +A+ S+P++ QIRQ++R SLK+IL KR+ DS+ L + E +  K+A  IEKE+F+ F+ TD
Sbjct: 660  SAAPSQPNS-QIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKIALHIEKEMFNLFQVTD 718

Query: 975  AKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHT 1034
             +YK+KYRS+MFNLKDPKN  LF +VL+ E++   L+R+ PEEL SKEL+ W+ R  R  
Sbjct: 719  NRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKERPARSV 778

Query: 1035 IEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLEKPEGSEKQ 1094
            +E   K   E ++   T    +   ++E   P+ + E   E       KS      +   
Sbjct: 779  MESRTKLHNESKK---TAPRQEAIPDLEDSPPVSDSEEQQESARAVPEKS------TAPL 829

Query: 1095 KEEVDSMSKDTTSQHRQHLFDLNCKICIGRMAPPVDDLSPKKVKVVVGVAR-----KHSD 1149
             +   SM KDTTSQHR HLFDLNCKIC G++    D+ +PKK K+   V +     KH  
Sbjct: 830  LDVFSSMLKDTTSQHRAHLFDLNCKICTGQVPSAEDEPAPKKQKLSASVKKEDLKSKHDS 889

Query: 1150 NEAESIADALSSTSNILASEFFEEEKQESPK-----STFSPAP 1187
            +  +   D+          E   E   ES        T+ P P
Sbjct: 890  SAPDPAPDSADEVMPEAVPEVASEPGLESASHPNVDRTYFPGP 932



 Score = 72.4 bits (176), Expect = 4e-12
 Identities = 67/291 (23%), Positives = 125/291 (42%), Gaps = 49/291 (16%)

Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770
           + P+     C++PH NRFM+ C RC++WFHGDCVG+S ++ + +    ++Y+C  C    
Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323

Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822
            +++  +E  D      Q   ++  GD    +C  +G + + ++ D+       K  + +
Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377

Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867
            K K+KI +         +  G G       +S  C ++ I K   A ++ +      + 
Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437

Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGV--------LNVHPA 916
             +EK +  P++ +   C    G K S        E K+  V+K V        L    A
Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAVVVPARSEALGKEAA 497

Query: 917 ASASKPS------ADQIRQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATK 961
             +S PS       + ++     +    L+ + T  + +  E+ AA  A+K
Sbjct: 498 CESSTPSWASDHNYNAVKPEKTAAPSPSLLYKSTKEDRRSEEKAAAMAASK 548


>gi|47271475 SPOC domain containing 1 [Homo sapiens]
          Length = 1216

 Score =  193 bits (490), Expect = 2e-48
 Identities = 152/473 (32%), Positives = 225/473 (47%), Gaps = 74/473 (15%)

Query: 887  GEKASKPGTHEKQEMKKKKVEKGVLNVHPAASAS----KPSAD-QIRQSVRHSLKDILMK 941
            G+ +S P   +   M+    E+  L   P  SA     KPS    +R +V  S++++L  
Sbjct: 566  GDPSSDPACSQSGPME---AEEDSLPEQPEDSAQLQQEKPSLYIGVRGTVVRSMQEVLWT 622

Query: 942  RLTD-SNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKV 1000
            RL +  +  + EE    +A  IE  L+   + T+ +YK KYRSL+FNL+DP+N  LF KV
Sbjct: 623  RLRELPDPVLSEEVVEGIAAGIEAALWDLTQGTNGRYKTKYRSLLFNLRDPRNLDLFLKV 682

Query: 1001 LKGEVTPDHLIRMSPEELASKELAAWRRRENRHTIEMIEKEQREVERRPITKITHKGEIE 1060
            + G+VTP  L+RMS  +LA +ELA WR +E +  + +IE++Q+E  R P +K+THKGE+E
Sbjct: 683  VHGDVTPYDLVRMSSMQLAPQELARWRDQEEKRGLNIIEQQQKEPCRLPASKMTHKGEVE 742

Query: 1061 IESDAPMKEQEAAMEIQEPAANKSLEKPE-GSEKQKEEVDSMSKDTTSQHRQHLFDLNCK 1119
            I+ D    +Q   +E         L  P+   +   + +   S+DTT QH  H  D NC 
Sbjct: 743  IQRD---MDQTLTLE--------DLVGPQMFMDCSPQALPIASEDTTGQHDHHFLDPNCH 791

Query: 1120 ICIGRMAPPVDDLSPKKVKVVVGVARKHSDNEAESIADALSSTSNILASEFFEEEKQESP 1179
            IC         D  P             S+    S   A S   NI      +       
Sbjct: 792  IC--------KDWEP-------------SNELLGSFEAAKSCGDNIFQKALSQ------- 823

Query: 1180 KSTFSPAPRPEMPGTVEVESTF-------------LARLNFI-----WKGFINMPSVAKF 1221
                +P P PEMP T E+  T               A    +     W+G ++M S+ +F
Sbjct: 824  ----TPMPAPEMPKTRELSPTEPQDRVPPSGLHVPAAPTKALPCLPPWEGVLDMFSIKRF 879

Query: 1222 VTKAYPVSGSPEYLTEDLPDSIQVGGRISPQTVWDYVEKIKASGTKEICVVRFTPVTEED 1281
              +A  VSG    L + LP  I+  G I    VWD +  I  +  K++CVVR  P    D
Sbjct: 880  RARAQLVSGHSCRLVQALPTVIRSAGCIPSNIVWDLLASICPAKAKDVCVVRLCPHGARD 939

Query: 1282 QISYTLLFAYFSSRKRYGVAANNMKQVKDMYLIPLGATDKIPHPLVPFDGPGL 1334
              +  LL++Y + R+R+G+A+    +   M L+PL A   +P  L P  GPGL
Sbjct: 940  TQNCRLLYSYLNDRQRHGLAS---VEHMGMVLLPLPAFQPLPTRLRPLGGPGL 989


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 49/151 (32%), Positives = 83/151 (54%), Gaps = 2/151 (1%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            +D RR ERR      R+D++  +R   R + DR+R         RER EKE E E ER R
Sbjct: 656  RDERREERRVDRVDDRRDERARERDRERER-DRERERERERERDRER-EKERELERERAR 713

Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
             R+R ++K+RDR+   +   D+ER R    DR  + +  R+ R  +++ ++ +  + E++
Sbjct: 714  EREREREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERE 773

Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            +ER + + +E E+ RD   KD+   DR + +
Sbjct: 774  RERARERDKERERQRDWEDKDKGRDDRREKR 804



 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 49/169 (28%), Positives = 86/169 (50%), Gaps = 21/169 (12%)

Query: 1888 KDIRRPERRHSDP---WGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944
            +D R  ++R S P    GR D+ + D      + DR     D    +R+R   E E++ E
Sbjct: 632  RDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDR---ERERDRE 688

Query: 1945 RHRRRDRSQDKDRDR-------KSRE-EGHKDKERARLSHGDRGTDGKASRDSRNVDKKP 1996
            R R R+R +D++R++       ++RE E  ++KER R    DR  D +  R+     +K 
Sbjct: 689  RERERERERDREREKERELERERAREREREREKERDRERDRDRDHDRERERERERDREKE 748

Query: 1997 DKPKSEDYEKDKEREKSKHREGEKDRDR-------YHKDRDHTDRTKSK 2038
             + + E+ E+++ERE+ + RE E++R+R         + RD  D+ K +
Sbjct: 749  REREREERERERERERERERERERERERARERDKERERQRDWEDKDKGR 797



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 39/153 (25%), Positives = 74/153 (48%), Gaps = 5/153 (3%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949
            R  ER       R+ +++L+R   R + +R+R         R+R H++E E+E ER R +
Sbjct: 689  RERERERERDREREKERELERERARER-EREREKERDRERDRDRDHDRERERERERDREK 747

Query: 1950 DRS---QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            +R    ++++R+R+   E  +++ER R    +R  + +  RD  + DK  D  + +  E 
Sbjct: 748  EREREREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEI 807

Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
             ++R      +  K + RY  +   + R   KR
Sbjct: 808  REDRNPRDGHDERKSKKRYRNEGSPSPRQSPKR 840



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 31/142 (21%), Positives = 67/142 (47%), Gaps = 1/142 (0%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  ER  +    R+ +++ DR  +R + D  R         RE+  +   +E ER R R+
Sbjct: 705  RELERERAREREREREKERDRERDRDR-DHDRERERERERDREKEREREREERERERERE 763

Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKER 2010
            R ++++R+R+      +DKER R    +    G+  R  +  + + D+   + +++ K +
Sbjct: 764  RERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSK 823

Query: 2011 EKSKHREGEKDRDRYHKDRDHT 2032
            ++ ++      R    + R+H+
Sbjct: 824  KRYRNEGSPSPRQSPKRRREHS 845



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 41/154 (26%), Positives = 72/154 (46%), Gaps = 14/154 (9%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  ER       R  ++  DR  +R + +R+R        +RER E+E E+E ER R R+
Sbjct: 711  RAREREREREKERDRERDRDRDHDRER-ERERERDREKEREREREERERERERERERERE 769

Query: 1951 RSQDKDRDR-----KSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
            R ++++R R     + R+   +DK++ R    DR    +  R+ RN     D+ KS+   
Sbjct: 770  RERERERARERDKERERQRDWEDKDKGR---DDRREKREEIREDRNPRDGHDERKSKKRY 826

Query: 2006 KDK-----EREKSKHREGEKDRDRYHKDRDHTDR 2034
            +++      +   + RE   D D Y+   D  ++
Sbjct: 827  RNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEK 860



 Score = 52.8 bits (125), Expect = 3e-06
 Identities = 38/131 (29%), Positives = 64/131 (48%), Gaps = 26/131 (19%)

Query: 1933 ERHEKEWEQESE---RHRRRDRSQDKDRDRKS----REEGHKD-------KERARLSHGD 1978
            ER  ++  ++S    RH  RDR  +++RD++     R +G  D       +E  R+   D
Sbjct: 610  ERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDERREERRVDRVD 669

Query: 1979 RGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREK----------SKHREGEKDRDRYH-K 2027
               D +A    R  ++  ++ +  + E+D+EREK           + RE EK+RDR   +
Sbjct: 670  DRRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDR 729

Query: 2028 DRDHTDRTKSK 2038
            DRDH DR + +
Sbjct: 730  DRDH-DRERER 739



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 40/137 (29%), Positives = 62/137 (45%), Gaps = 12/137 (8%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962
            R DQ +   P      DRQ   S S        +++    S     RDR Q++DR    R
Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309

Query: 1963 EEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKD 2021
            E     +ER R     R  D  A +D  RN D+  D+ +    E+++ERE+ K R+ +++
Sbjct: 1310 E-----RERERRDTRQREWDRDADKDWPRNRDR--DRLR----ERERERERDKRRDLDRE 1358

Query: 2022 RDRYHKDRDHTDRTKSK 2038
            R+R   D    DR + +
Sbjct: 1359 RERLISDSVERDRDRDR 1375



 Score = 50.1 bits (118), Expect = 2e-05
 Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 24/173 (13%)

Query: 1886 QVKDIRRPERR---HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQE 1942
            ++++  R E R    +D  GR   +  + P    +G R     DSH      H+  WE  
Sbjct: 542  EIRNESRNESRSEIRNDRMGRSRGRVPELPEKGSRGSRGS-QIDSHSSNSNYHDS-WETR 599

Query: 1943 S---ERHR-----RRDRSQDKDRDRKSREEGHKD-KERAR-----LSHGDRGTDGKAS-- 1986
            S   ER R      RD+++D   +R+  E   +D +ER +     + H  R  + +    
Sbjct: 600  SSYPERDRYPERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRHQGRNDELERDER 659

Query: 1987 RDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            R+ R VD+  D+      E+D+ERE+ + RE E++R+R   DR+     + +R
Sbjct: 660  REERRVDRVDDRRDERARERDRERERDRERERERERER---DREREKERELER 709



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 37/162 (22%), Positives = 72/162 (44%), Gaps = 20/162 (12%)

Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945
            ++  ++R E   S    RQD +      +  + DRQ          R+R ++    E +R
Sbjct: 1250 RIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDR 1309

Query: 1946 HRRRDRSQDKDR--DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003
             R R+R   + R  DR + ++  ++++R RL   +R  +    RD   +D++ ++  S+ 
Sbjct: 1310 ERERERRDTRQREWDRDADKDWPRNRDRDRLRERERERERDKRRD---LDRERERLISDS 1366

Query: 2004 YEKDKEREKSK---------------HREGEKDRDRYHKDRD 2030
             E+D++R++ +                 EGE +RD     RD
Sbjct: 1367 VERDRDRDRDRTFESSQIESVKRCEAKLEGEHERDLESTSRD 1408



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 46/186 (24%), Positives = 75/186 (40%), Gaps = 28/186 (15%)

Query: 1860 HLPGQPQRMMGPLSQASRYIGPQ-----NFYQVKDIRRPERRHSDPWGRQDQQQLDRPFN 1914
            H P  P+R   P     R + P      + Y    +  P+R+ S P  R   ++      
Sbjct: 345  HSPS-PRRKRTPSPSYQRTLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMRE------ 397

Query: 1915 RGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDR-----KSREEGHKDK 1969
            +G+ D +R  S SH  + ER E       +   +RDR +D   +R     +S    H+D 
Sbjct: 398  KGRHDHERT-SQSHDRRHERRE-------DTRGKRDREKDSREEREYEQDQSSSRDHRDD 449

Query: 1970 ERARLSHGDR-GTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRY-HK 2027
               R     R   D +  R+ R+     D  +  DY +D  +E    R+    RD + ++
Sbjct: 450  REPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDYSRD-TKESRDPRDSRSTRDAHDYR 508

Query: 2028 DRDHTD 2033
            DR+  D
Sbjct: 509  DREGRD 514



 Score = 42.0 bits (97), Expect = 0.006
 Identities = 42/160 (26%), Positives = 72/160 (45%), Gaps = 22/160 (13%)

Query: 1881 PQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE 1940
            P   YQ + +  P RR + P+       L  P  +    R R  S      R  HE+  +
Sbjct: 355  PSPSYQ-RTLTPPLRRSASPY---PSHSLSSPQRKQSPPRHR--SPMREKGRHDHERTSQ 408

Query: 1941 QESERHRRRDRSQDK-DRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999
                RH RR+ ++ K DR++ SREE   +++++            +SRD R+ D++P   
Sbjct: 409  SHDRRHERREDTRGKRDREKDSREEREYEQDQS------------SSRDHRD-DREPRDG 455

Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +     +D  R++ + R+    RD   + RD++  TK  R
Sbjct: 456  RDRRDARD-TRDRRELRDSRDMRDS-REMRDYSRDTKESR 493



 Score = 40.8 bits (94), Expect = 0.014
 Identities = 38/161 (23%), Positives = 72/161 (44%), Gaps = 17/161 (10%)

Query: 1873 SQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKR 1932
            S +SR   P++  QV   R       D    +D+ + DR       +R+R   D+   + 
Sbjct: 1272 SHSSRRSSPESDRQVHS-RSGSFDSRDRLQERDRYEHDR-------ERERERRDTRQREW 1323

Query: 1933 ERH-EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARL----SHGDRGTDGKASR 1987
            +R  +K+W +  +R R R+R ++++RD++       D+ER RL       DR  D   + 
Sbjct: 1324 DRDADKDWPRNRDRDRLRERERERERDKRR----DLDRERERLISDSVERDRDRDRDRTF 1379

Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKD 2028
            +S  ++         + E +++ E +       D++R  KD
Sbjct: 1380 ESSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKD 1420



 Score = 35.0 bits (79), Expect = 0.75
 Identities = 40/177 (22%), Positives = 68/177 (38%), Gaps = 21/177 (11%)

Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQ 1941
            Q  ++ KD  R +RR      R+D+   D    R    R R        +  +  +E   
Sbjct: 787  QRDWEDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSP 846

Query: 1942 ESERHRRRDRSQDKDR---------DRKSREEGHKDKER-ARLSHGDRGTDGKASRDSRN 1991
            +S+ +   D   +K R         + +S    H  ++R  R    DR  + K S  SR 
Sbjct: 847  DSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKEEDRKPERKES--SRR 904

Query: 1992 VDKKPDKPKSEDYEKDKER----EKSKHREGE-----KDRDRYHKDRDHTDRTKSKR 2039
             +++  K K    +K +E+    E S+ R  +     +  DR   DR H +  K  +
Sbjct: 905  YEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAHDENKKKAK 961



 Score = 35.0 bits (79), Expect = 0.75
 Identities = 29/115 (25%), Positives = 53/115 (46%), Gaps = 20/115 (17%)

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRG-------------TDGKASRDSRN 1991
            R R + +S +   +RKSR +  K  E +R +  DR              +D +    S +
Sbjct: 1233 RDREKTKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRSGS 1292

Query: 1992 VDKKPDKPKSEDYEKDKEREK----SKHREGEKDRDR---YHKDRDHTDRTKSKR 2039
             D +    + + YE D+ERE+    ++ RE ++D D+    ++DRD     + +R
Sbjct: 1293 FDSRDRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRDRDRLRERERER 1347



 Score = 32.0 bits (71), Expect = 6.3
 Identities = 33/142 (23%), Positives = 58/142 (40%), Gaps = 22/142 (15%)

Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG- 1977
            DRQ  + +    K ER E     E +  + +  S DK R++    E  + + +  + H  
Sbjct: 884  DRQGRWKEEDR-KPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQ 942

Query: 1978 --DRGTDGKASRDSRN---VDKKPDKPK---------------SEDYEKDKEREKSKHRE 2017
              DR T  +A  +++    + KKP K K               SED +    ++  K + 
Sbjct: 943  SEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQKKKS 1002

Query: 2018 GEKDRDRYHKDRDHTDRTKSKR 2039
             EK R +   D D +D   +++
Sbjct: 1003 IEKKRKKSKGDSDISDEEAAQQ 1024


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 81.3 bits (199), Expect = 9e-15
 Identities = 42/153 (27%), Positives = 82/153 (53%), Gaps = 7/153 (4%)

Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945
            ++   R   ++  +  G++++++ +    R + +R+R        +    E+E E+E E+
Sbjct: 280  EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339

Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
             R R+R +D+DRDR    +  +D+ER      DR  D + S D RN D+   + KS D E
Sbjct: 340  ERERERERDRDRDRTKERDRDRDRER------DRDRDRERSSD-RNKDRSRSREKSRDRE 392

Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            +++ERE+ + RE E++R+R  +     +R + +
Sbjct: 393  RERERERERERERERERERERERERERERERER 425



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 35/152 (23%), Positives = 76/152 (50%), Gaps = 13/152 (8%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            ++  R   R  +   R+ +++ +R   + K   +    D    + +  +++ ++E +R R
Sbjct: 310  RERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDRERDRDR 369

Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
             R+RS D+++DR    E  +D+ER R    +R             +++ ++ +  + E++
Sbjct: 370  DRERSSDRNKDRSRSREKSRDRERERERERER-------------ERERERERERERERE 416

Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +ERE+ + RE +K RDR   + D  +R K +R
Sbjct: 417  REREREREREKDKKRDREEDEEDAYERRKLER 448



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 47/169 (27%), Positives = 77/169 (45%), Gaps = 30/169 (17%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949
            R  ER       R  ++  DR   R + DR R  S   +  R R  EK  ++E ER R R
Sbjct: 341  RERERERDRDRDRTKERDRDRDRERDR-DRDRERSSDRNKDRSRSREKSRDRERERERER 399

Query: 1950 DRSQDKDRDRKSREEGHKDKERARL----SHGDRGTDGKASRDSRNVDKK---------- 1995
            +R ++++R+R+   E  +++ER R        DR  D + + + R +++K          
Sbjct: 400  EREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEAAYQE 459

Query: 1996 -------PDKPKSEDYEKDKEREKSKHREGEKDRDR-------YHKDRD 2030
                    ++ K+ +YEK+ ERE+ + RE  K+  R       Y  DRD
Sbjct: 460  RLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRD 508



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 23/106 (21%), Positives = 56/106 (52%), Gaps = 4/106 (3%)

Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGD 1978
            D  ++Y  S   KR R  ++  +  ER R+R++ + ++  ++   EGH D + A L   +
Sbjct: 508  DDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPD-AELQRME 566

Query: 1979 RGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDR 2024
            +  +    R    + ++P+  + E+ +++KE ++ +  E E++ ++
Sbjct: 567  QEAE---RRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQ 609



 Score = 38.9 bits (89), Expect = 0.052
 Identities = 23/54 (42%), Positives = 26/54 (48%), Gaps = 3/54 (5%)

Query: 1807 HLKSSPPGFPFPGPPNFPPQSMFGFPPHLPP--PLLPPPGFGFAQNPMVPWPPV 1858
            HL   P G P   PP  PP    GFPP +PP  P++P P    A  P V  P V
Sbjct: 6    HLNRPPMGIPAL-PPGIPPPQFPGFPPPVPPGTPMIPVPMSIMAPAPTVLVPTV 58



 Score = 37.0 bits (84), Expect = 0.20
 Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 12/70 (17%)

Query: 1817 FPGPPNFPPQSMFGFPPHLPPPLLP------PPGFGFAQNPMVPWPPVVHLPGQPQRMMG 1870
            FP   N PP  +   PP +PPP  P      PPG      PM+P P  +  P  P  ++ 
Sbjct: 3    FPPHLNRPPMGIPALPPGIPPPQFPGFPPPVPPG-----TPMIPVPMSIMAPA-PTVLVP 56

Query: 1871 PLSQASRYIG 1880
             +S   +++G
Sbjct: 57   TVSMVGKHLG 66


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
            sapiens]
          Length = 600

 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 46/155 (29%), Positives = 85/155 (54%), Gaps = 14/155 (9%)

Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951
            R   R  +   R++++Q +R  +R    R+R      H KR+RH    E++ +R + R+R
Sbjct: 54   RERNRQKERERRREKRQTERETDR---KRERRREKDRHRKRDRHR---ERQRDREKERER 107

Query: 1952 SQDKDRDRKSREEGHKDKERARLS--HGDRG----TDGKASRD-SRNVDKKPDKPKSEDY 2004
              D++RDR+  +E ++ KER R +   G+RG    TDG+  R+  R+ +K+ ++    + 
Sbjct: 108  QTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRER 167

Query: 2005 EKDKEREKSKHREGEKDR-DRYHKDRDHTDRTKSK 2038
            ++  ER + K RE EK+R +R  ++R      K++
Sbjct: 168  QRQTERNRQKEREREKNRQERRERERQREKENKTE 202



 Score = 73.9 bits (180), Expect = 1e-12
 Identities = 45/154 (29%), Positives = 80/154 (51%), Gaps = 4/154 (2%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKG-DRQRFYSDSHHLKRERHEKEWEQESERH 1946
            +D R+ ER       RQ + + DR   R +   R+R      + KRER E+E E+E ER 
Sbjct: 272  RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER-ERERERERERQ 330

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLS--HGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R  +R ++K+R+RK + +   D+ER R +   G R  + +  R+     +   + +  + 
Sbjct: 331  RETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERER 390

Query: 2005 EKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            ++D++R+K + R+ EKDRD   +     +R K +
Sbjct: 391  DRDRDRQKERERQTEKDRDGQRETEKQREREKDR 424



 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 41/152 (26%), Positives = 78/152 (51%), Gaps = 2/152 (1%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            ++  R ERR  +    ++ +  DR   RG+ +R+R        +R+R + + E++ +R  
Sbjct: 181  REKNRQERRERERQREKENKTEDRHSERGR-ERERERETETETERKR-QTDRERDRQRKT 238

Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
             R+R +  +R+R S  E  +DKER R    DR  D +     R  D+K  +    D E +
Sbjct: 239  EREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETE 298

Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            ++RE+ + RE E++R+R  +     +R + ++
Sbjct: 299  RKRERQRERERERERNRKRERERERERERERQ 330



 Score = 71.2 bits (173), Expect = 9e-12
 Identities = 47/153 (30%), Positives = 74/153 (48%), Gaps = 6/153 (3%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949
            RR ER       R+ Q++ +R   R  K +R+R        +RE  E++ E+E ER R+R
Sbjct: 289  RRTERDRETERKRERQRERERERERNRKRERERERERERERQRET-ERDREKERERKRKR 347

Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSE----DYE 2005
                D++R+R++  EG +  ER R    +R       R+ R  D+  D+ K      + +
Sbjct: 348  QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407

Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            +D +RE  K RE EKDR+         +R K K
Sbjct: 408  RDGQRETEKQREREKDRESERGRERGREREKQK 440



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  ER        + ++Q DR  +R +   +     +   +    E E ++E ER R RD
Sbjct: 210  RERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRD 269

Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPDKPKSEDYEKD 2007
            R  D+DR +K RE    D++R R +  DR T+ K  R     R  ++   + +  + E++
Sbjct: 270  R--DRDRRQKERER-QTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERE 326

Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +ER++   R+ EK+R+R  K +   DR ++++
Sbjct: 327  RERQRETERDREKERERKRKRQTEMDRERNRQ 358



 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 43/153 (28%), Positives = 87/153 (56%), Gaps = 16/153 (10%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            +D  +   R +D   R+ Q+Q +R  NR K +R+R  +     ++ER E+E ++E E ++
Sbjct: 153  RDAEKERERQTD---RERQRQTER--NRQK-EREREKN-----RQERRERERQREKE-NK 200

Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
              DR  ++ R+R+   E   + ER R +  +R    K  R+    +K+ ++ ++ + E +
Sbjct: 201  TEDRHSERGRERERERETETETERKRQTDRERDRQRKTERER---EKQAERERASERETE 257

Query: 2008 KEREKSKHREGEKDRDRYHKDRD-HTDRTKSKR 2039
            +++E+ + R+ ++DRDR  K+R+  TDR + +R
Sbjct: 258  RDKERERERDRDRDRDRRQKERERQTDRKRQRR 290



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 34/109 (31%), Positives = 60/109 (55%), Gaps = 2/109 (1%)

Query: 1929 HLKRERHEKEWEQESERHRRRDRSQ-DKDRDRKSREEGHKDKERARLSHGDRGTDGKASR 1987
            H   +  ++E  ++ ER RRR++ Q +++ DRK      KD+ R R  H +R  D +  R
Sbjct: 46   HKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKER 105

Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTK 2036
            + R  D++ D+ + ++  + KERE+   REGE+ RDR    +   +R +
Sbjct: 106  E-RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQR 153



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/159 (25%), Positives = 84/159 (52%), Gaps = 11/159 (6%)

Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951
            +   R  D    +D++Q +R     +  ++R   D    ++   ++E E+E ER+R+R+R
Sbjct: 260  KERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRER 319

Query: 1952 SQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPDKPKSEDYEKDK 2008
             ++++R+R+ + E  +D+E+ R     R T+    R+    R   ++ ++ +  + E+D+
Sbjct: 320  ERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDR 379

Query: 2009 -------EREKSKHREGEKDRDRY-HKDRDHTDRTKSKR 2039
                   ERE+ + R+ +K+R+R   KDRD    T+ +R
Sbjct: 380  QSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQR 418



 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 34/124 (27%), Positives = 65/124 (52%), Gaps = 4/124 (3%)

Query: 1919 DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGD 1978
            DR+R        +RE+ + E E + +R RRR++ + + RDR    +  ++KER R +  +
Sbjct: 53   DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE 112

Query: 1979 RGTDGKASRD---SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRT 2035
            R    +  R+    R  + + +  +  D + D +RE+ + R+ EK+R+R   DR+   +T
Sbjct: 113  RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERER-QTDRERQRQT 171

Query: 2036 KSKR 2039
            +  R
Sbjct: 172  ERNR 175



 Score = 60.5 bits (145), Expect = 2e-08
 Identities = 37/154 (24%), Positives = 77/154 (50%), Gaps = 6/154 (3%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949
            R  +R+      R+ Q + +R   R  + D++R         R+R +KE E++++R R+R
Sbjct: 230  RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQR 289

Query: 1950 ----DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDY 2004
                DR  ++ R+R+   E  +++ R R    +R  + +  R++ R+ +K+ ++ +    
Sbjct: 290  RTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQT 349

Query: 2005 EKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            E D+ER +   REG +  +R  +     DR  ++
Sbjct: 350  EMDRERNRQTGREGRRQAERERERERERDRQSAR 383



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 56/204 (27%), Positives = 93/204 (45%), Gaps = 54/204 (26%)

Query: 1889 DIRRPERRHSDPWGRQD---QQQLDRPFNRGKG-----DRQRFYSDSHHLKRERH-EKEW 1939
            D +R  RR  D   ++D   ++Q DR   R +      DRQR    +   +RER  E+E 
Sbjct: 76   DRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREG 135

Query: 1940 EQ--------ESERHRRRD----RSQDKDRDRKSREEGHKDKERARLS------------ 1975
            E+        + ER R+RD    R +  DR+R+ + E ++ KER R              
Sbjct: 136  ERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQR 195

Query: 1976 ---------HGDRGTDGKASRDS-------RNVDKKPDKPKSEDYEKDK--EREKSKHRE 2017
                     H +RG + +  R++       R  D++ D+ +  + E++K  ERE++  RE
Sbjct: 196  EKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255

Query: 2018 GEKDRDRYH---KDRDHTDRTKSK 2038
             E+D++R     +DRD   R K +
Sbjct: 256  TERDKERERERDRDRDRDRRQKER 279



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 38/151 (25%), Positives = 78/151 (51%), Gaps = 8/151 (5%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R+ ER       R+ Q++ +R   +   +R+R       + RER+ ++  +E  R   R+
Sbjct: 315  RKRERERERERERERQRETERDREK---ERERKRKRQTEMDRERN-RQTGREGRRQAERE 370

Query: 1951 RSQDKDRDRKS---REEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
            R ++++RDR+S   REE  +D++R R    +R T+ K     R  +K+ ++ K  + E+ 
Sbjct: 371  RERERERDRQSAREREERERDRDRDRQKERERQTE-KDRDGQRETEKQREREKDRESERG 429

Query: 2008 KEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            +ER + + ++  ++RDR  +      R + +
Sbjct: 430  RERGREREKQKGRERDRERQTDRQAGRQRKR 460



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 43/173 (24%), Positives = 87/173 (50%), Gaps = 17/173 (9%)

Query: 1882 QNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH------ 1935
            +N  + ++ RR +R+      R+ +++ ++  +R K DR R        +RER       
Sbjct: 56   RNRQKERERRREKRQTERETDRKRERRREKDRHR-KRDRHRERQRDREKERERQTDRERD 114

Query: 1936 ---EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RN 1991
               EKE  ++ ER R  +R  ++ RDR++  +  ++++R      +R TD +  R + RN
Sbjct: 115  RQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERN 174

Query: 1992 VDKKPDKPKSEDYEKDKEREKSKH-----REGEKDRDRYHKDRDHTDRTKSKR 2039
              K+ ++ K+    +++ER++ K      R  E+ R+R  ++R+    T+ KR
Sbjct: 175  RQKEREREKNRQERRERERQREKENKTEDRHSERGRER-ERERETETETERKR 226



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 30/113 (26%), Positives = 51/113 (45%), Gaps = 5/113 (4%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK-----EWEQESERHRRRDRSQDKDR 1957
            R+ +++ DR   R + +R+R        +RER  +     + E E +R R +DR  ++ R
Sbjct: 371  RERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGR 430

Query: 1958 DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKER 2010
            +R    E  K +ER R    DR    +  R +  V+  P   +S   + D  R
Sbjct: 431  ERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNR 483



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 29/104 (27%), Positives = 52/104 (50%), Gaps = 5/104 (4%)

Query: 1874 QASRYIGPQNFYQVKDIRRPERRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKR 1932
            + +R  G +   Q +  R  ER       R+ ++++ DR  +R K +R+R        +R
Sbjct: 354  ERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQK-ERERQTEKDRDGQR 412

Query: 1933 E---RHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERAR 1973
            E   + E+E ++ESER R R R ++K + R+   E   D++  R
Sbjct: 413  ETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGR 456



 Score = 35.4 bits (80), Expect = 0.57
 Identities = 29/99 (29%), Positives = 50/99 (50%), Gaps = 16/99 (16%)

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            RRR  SQ+  R R+   + HKD +       DR  + +  R+ R   +K    +  D ++
Sbjct: 28   RRRPGSQESPR-RRGLGQAHKDADG-----DDRERNRQKERERRR--EKRQTERETDRKR 79

Query: 2007 DKEREKSKHREGEKDRDR-YHKDRD-----HTDRTKSKR 2039
            ++ REK +HR+  +DR R   +DR+      TDR + ++
Sbjct: 80   ERRREKDRHRK--RDRHRERQRDREKERERQTDRERDRQ 116


>gi|239749424 PREDICTED: hypothetical protein XP_002347041 [Homo
            sapiens]
          Length = 287

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%)

Query: 869  SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927
            S EK     K+   +T      ++  +     +  +K E    + + ++    PS +D +
Sbjct: 67   STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 126

Query: 928  RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987
            R   R  L   L  R  D  + +  ++  ++ ++IE+ ++   R+TD KYKN+ RS + N
Sbjct: 127  RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 183

Query: 988  LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035
            LKD KN  L K VL G + PD   RM+ EE+AS EL   R+   +  I
Sbjct: 184  LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 231


>gi|5803191 transcription elongation factor A 1 isoform 1 [Homo
            sapiens]
          Length = 301

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%)

Query: 869  SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927
            S EK     K+   +T      ++  +     +  +K E    + + ++    PS +D +
Sbjct: 81   STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 140

Query: 928  RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987
            R   R  L   L  R  D  + +  ++  ++ ++IE+ ++   R+TD KYKN+ RS + N
Sbjct: 141  RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 197

Query: 988  LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035
            LKD KN  L K VL G + PD   RM+ EE+AS EL   R+   +  I
Sbjct: 198  LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 245


>gi|45439355 transcription elongation factor A 1 isoform 2 [Homo
            sapiens]
          Length = 280

 Score = 73.6 bits (179), Expect = 2e-12
 Identities = 50/168 (29%), Positives = 82/168 (48%), Gaps = 4/168 (2%)

Query: 869  SEEKSEKIPKESTTVTCTGEKASKPGTHEKQEMKKKKVEKGVLNVHPAASASKPS-ADQI 927
            S EK     K+   +T      ++  +     +  +K E    + + ++    PS +D +
Sbjct: 60   STEKDLDEKKKEPAITSQNSPEAREESTSSGNVSNRKDETNARDTYVSSFPRAPSTSDSV 119

Query: 928  RQSVRHSLKDILMKRLTDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFN 987
            R   R  L   L  R  D  + +  ++  ++ ++IE+ ++   R+TD KYKN+ RS + N
Sbjct: 120  RLKCREMLAAAL--RTGDDYIAIGADEE-ELGSQIEEAIYQEIRNTDMKYKNRVRSRISN 176

Query: 988  LKDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035
            LKD KN  L K VL G + PD   RM+ EE+AS EL   R+   +  I
Sbjct: 177  LKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEAI 224


>gi|169167715 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 285

 Score = 72.8 bits (177), Expect = 3e-12
 Identities = 45/163 (27%), Positives = 84/163 (51%), Gaps = 15/163 (9%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRG-KGDRQRFYSDSHHLKRER-----HEKEWEQESE 1944
            R  +R+ +    R+  +++++  +R  K DR+R        KRER      E E E++ E
Sbjct: 66   RERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRETETERQEE 125

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R R+RDR ++KDR+R+ + E   DK+R   +  DR  + +     R  D++ ++ K  + 
Sbjct: 126  RERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRERERQKQRET 185

Query: 2005 EKDKEREKSKHREG---------EKDRDRYHKDRDHTDRTKSK 2038
             +D++RE+ + +E          E+++DRY +     DR K +
Sbjct: 186  RRDRDRERQREKEDRERDRDRQKEREKDRYRERETGRDRDKER 228



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 41/148 (27%), Positives = 77/148 (52%), Gaps = 15/148 (10%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDK--DRDRK 1960
            R+ Q++ +R   R K +R R         R+R  K  ++E +R R RDR +++  DRDR+
Sbjct: 60   RERQRERERQRKRAK-ERHREKDREIEKDRDRQRKR-DRERQRWRDRDRKRERWGDRDRE 117

Query: 1961 SREEGHKDKERARLSHGDRGTDGKASRD-----SRNVDKKPDKPKSEDY-----EKDKER 2010
            +  E  +++ER R    ++  + +  R+      R ++ + D+ +  +       +D+ER
Sbjct: 118  TETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDRDREREMGETERYRDRER 177

Query: 2011 EKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
            E+ K RE  +DRDR  + R+  DR + +
Sbjct: 178  ERQKQRETRRDRDR-ERQREKEDRERDR 204



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 36/120 (30%), Positives = 67/120 (55%), Gaps = 15/120 (12%)

Query: 1931 KRERHEKEWEQESERHRRRDRSQD----KDRDRKSREEGH----KDKERARLSHGDRGTD 1982
            +RER ++E E++ +R + R R +D    KDRDR+ + +      +D++R R   GDR  +
Sbjct: 59   ERER-QRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRDRKRERWGDRDRE 117

Query: 1983 GKASRDSRNVDKKPDKPKSEDYEKDKERE----KSKHREGEKDRDRYHKDRDHTDRTKSK 2038
             +  R     +++ D+ + +D E+ ++RE    K +  E EKDRDR  ++   T+R + +
Sbjct: 118  TETERQEER-ERQRDRKREKDRERQRQREIGIDKDREIETEKDRDR-EREMGETERYRDR 175



 Score = 50.8 bits (120), Expect = 1e-05
 Identities = 30/104 (28%), Positives = 54/104 (51%), Gaps = 6/104 (5%)

Query: 1941 QESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK 2000
            +E ER R R+R + + ++R   ++   +K+R R    DR       RD R  ++  D+ +
Sbjct: 58   RERERQRERERQRKRAKERHREKDREIEKDRDRQRKRDRERQRWRDRD-RKRERWGDRDR 116

Query: 2001 SEDYEKDKEREKSKHREGEKDRDRYHK-----DRDHTDRTKSKR 2039
              + E+ +ERE+ + R+ EKDR+R  +     D+D    T+  R
Sbjct: 117  ETETERQEERERQRDRKREKDRERQRQREIGIDKDREIETEKDR 160



 Score = 38.1 bits (87), Expect = 0.089
 Identities = 26/94 (27%), Positives = 44/94 (46%), Gaps = 8/94 (8%)

Query: 1903 RQDQQQLDRPFNRGKG------DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRS--QD 1954
            R+ + + DR   R  G      DR+R        +R+R  +   ++ +R R RDR   ++
Sbjct: 152  REIETEKDRDREREMGETERYRDRERERQKQRETRRDRDRERQREKEDRERDRDRQKERE 211

Query: 1955 KDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988
            KDR R+      +DKER R    ++  D + + D
Sbjct: 212  KDRYRERETGRDRDKERDRERQREKDRDRQKAID 245


>gi|18375619 death inducer-obliterator 1 isoform a [Homo sapiens]
          Length = 562

 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 37/234 (15%)

Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770
           + P+     C++PH NRFM+ C RC++WFHGDCVG+S ++ + +    ++Y+C  C    
Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323

Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822
            +++  +E  D      Q   ++  GD    +C  +G + + ++ D+       K  + +
Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377

Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867
            K K+KI +         +  G G       +S  C ++ I K   A ++ +      + 
Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437

Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGVLNVHPAAS 918
             +EK +  P++ +   C    G K S        E K+  V+K V  V PA S
Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV--VVPARS 489


>gi|18375617 death inducer-obliterator 1 isoform a [Homo sapiens]
          Length = 562

 Score = 71.6 bits (174), Expect = 7e-12
 Identities = 59/234 (25%), Positives = 106/234 (45%), Gaps = 37/234 (15%)

Query: 714 WTPSKQCGFCKKPHGNRFMVGCGRCDDWFHGDCVGLSLSQAQQMGEEDKEYVCVKCC--- 770
           + P+     C++PH NRFM+ C RC++WFHGDCVG+S ++ + +    ++Y+C  C    
Sbjct: 264 YDPNALYCICRQPHNNRFMICCDRCEEWFHGDCVGISEARGRLLERNGEDYICPNCTILQ 323

Query: 771 AEEDKKTEILDPDTLENQATVEFHSGDKT-MECEKLG-LSKHTTNDR------TKYIDDT 822
            +++  +E  D      Q   ++  GD    +C  +G + + ++ D+       K  + +
Sbjct: 324 VQDETHSETAD------QQEAKWRPGDADGTDCTSIGTIEQKSSEDQGIKGRIEKAANPS 377

Query: 823 VKHKVKILK---------RESGEG------RNSSDCRDNEIKKWQLAPLRKMGQPVLPRR 867
            K K+KI +         +  G G       +S  C ++ I K   A ++ +      + 
Sbjct: 378 GKKKLKIFQPVIEAPGASKCIGPGCCHVAQPDSVYCSNDCILKHAAATMKFLSSGKEQKP 437

Query: 868 SSEEKSEKIPKESTTVTC---TGEKASKPGTHEKQEMKKKKVEKGVLNVHPAAS 918
             +EK +  P++ +   C    G K S        E K+  V+K V  V PA S
Sbjct: 438 KPKEKMKMKPEKPSLPKCGAQAGIKISSVHKRPAPEKKETTVKKAV--VVPARS 489


>gi|201023341 FIP1 like 1 isoform 3 [Homo sapiens]
          Length = 520

 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 63/222 (28%), Positives = 100/222 (45%), Gaps = 35/222 (15%)

Query: 1820 PPNFPPQSMFGFPP-HLPPP-LLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASR 1877
            PP FPP    G PP HLPPP  LPPP       P++P P     PG P   + P  ++  
Sbjct: 283  PPFFPP----GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES-- 336

Query: 1878 YIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK 1937
              G  + Y  +  R      + P+G      +  P   G         D+         K
Sbjct: 337  --GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT--------SK 375

Query: 1938 EWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD 1997
            +W+  + R + RDR +D+DR+R    +  +D+ER R    +R  D   +    N D++  
Sbjct: 376  QWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPSVFNSDEERY 431

Query: 1998 KPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            + + E  E+  ER ++   + E+ R+R H++++ T R KS R
Sbjct: 432  RYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 471


>gi|40254978 FIP1 like 1 isoform 1 [Homo sapiens]
          Length = 594

 Score = 70.5 bits (171), Expect = 2e-11
 Identities = 63/222 (28%), Positives = 100/222 (45%), Gaps = 35/222 (15%)

Query: 1820 PPNFPPQSMFGFPP-HLPPP-LLPPPGFGFAQNPMVPWPPVVHLPGQPQRMMGPLSQASR 1877
            PP FPP    G PP HLPPP  LPPP       P++P P     PG P   + P  ++  
Sbjct: 357  PPFFPP----GAPPTHLPPPPFLPPPPTVSTAPPLIPPPGFPPPPGAPPPSLIPTIES-- 410

Query: 1878 YIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEK 1937
              G  + Y  +  R      + P+G      +  P   G         D+         K
Sbjct: 411  --GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT--------SK 449

Query: 1938 EWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD 1997
            +W+  + R + RDR +D+DR+R    +  +D+ER R    +R  D   +    N D++  
Sbjct: 450  QWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPSVFNSDEERY 505

Query: 1998 KPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            + + E  E+  ER ++   + E+ R+R H++++ T R KS R
Sbjct: 506  RYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 545


>gi|41350335 transcription elongation factor A (SII), 3 [Homo sapiens]
          Length = 348

 Score = 69.3 bits (168), Expect = 4e-11
 Identities = 55/214 (25%), Positives = 96/214 (44%), Gaps = 5/214 (2%)

Query: 831  KRESGEGRNSSDCRDNEIKKWQLAPLRKMGQPVLPRRSSEEKSEKIPKESTTVTCTGEKA 890
            K E GE R  +  ++  ++     P   +  P   R   + + + +  +S+  +     +
Sbjct: 86   KGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTRRDSVDSKSSASSSPKRPS 145

Query: 891  SKPGTHEKQEMKKKKVEKGVLNVHPAASASKPSADQIR-QSVRHSLKDILMKRL-TDSNL 948
             +     K + +  K     L    A+S    +   +   SVR    ++L   L  D + 
Sbjct: 146  VERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPCYLTGDSVRDKCVEMLSAALKADDDY 205

Query: 949  KVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNLKDPKNNILFKKVLKGEVTPD 1008
            K       K+A++IE  ++   + TD KY+N+ RS + NLKDP+N  L + VL G ++  
Sbjct: 206  KDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLSGAISAG 265

Query: 1009 HLIRMSPEELASKELAAWRRRENRHTIEMIEKEQ 1042
             + +M+ EE+AS EL   R   N  T E I + Q
Sbjct: 266  LIAKMTAEEMASDEL---RELRNAMTQEAIREHQ 296


>gi|239757964 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 290

 Score = 68.9 bits (167), Expect = 5e-11
 Identities = 45/146 (30%), Positives = 76/146 (52%), Gaps = 11/146 (7%)

Query: 1902 GRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKD 1956
            GR+ ++  DR   R +      D QR         RER EK+ E+E+ER R R R  +K+
Sbjct: 140  GRERERDRDREKERERQTEKDRDGQRETETERERDRER-EKQKERETERDRDRQRDTEKE 198

Query: 1957 RDRKSREEGHKDKERARLSHGDRGTDGKASRDS---RNVDKKPDKPKSEDYEKDKEREKS 2013
            R+R++  E  +D++R   +   R TD +  R++   R   +  D+ K  D E+D++ E+ 
Sbjct: 199  RERQTDRE--RDRQRKTQTERQRETDREGERETDRRRERQRDRDRGKERDRERDRKEERK 256

Query: 2014 KHREGEKDRDRYHKDRDHTDRTKSKR 2039
            K R+ E+ ++R  K ++   R   KR
Sbjct: 257  KERKKERKKERKEKKKEEKRREDKKR 282



 Score = 68.2 bits (165), Expect = 8e-11
 Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 23/160 (14%)

Query: 1902 GRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ-------D 1954
            GR   Q+  R +  G+  +     D    +R+R  ++ E+E +R R+RDR +       +
Sbjct: 52   GRLGSQESPRSWGLGQAHKDAD-GDDRQRERDRVREKTEKERDRDRKRDRERRRKEKETN 110

Query: 1955 KDRDRKSREEGHKDKER----ARLSHGDRGTDGKASRD-----SRNVDKKPD--KPKSED 2003
            ++RDR+ + E  +D+ER     R    DRG + +  RD      R  +K  D  +    +
Sbjct: 111  RNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETE 170

Query: 2004 YEKDKEREKSKHREGEKDRDRY---HKDRD-HTDRTKSKR 2039
             E+D+EREK K RE E+DRDR     K+R+  TDR + ++
Sbjct: 171  RERDREREKQKERETERDRDRQRDTEKERERQTDRERDRQ 210



 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 43/154 (27%), Positives = 80/154 (51%), Gaps = 16/154 (10%)

Query: 1897 HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRR----RDRS 1952
            H D  G   Q++ DR   R K +++R        +R R EKE  +  +R ++    RDR 
Sbjct: 69   HKDADGDDRQRERDRV--REKTEKERDRDRKRDRERRRKEKETNRNRDREKQTEIERDRE 126

Query: 1953 QDK------DRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDYE 2005
            ++K      +RDR    E  +D+E+ R    ++  DG+   ++ R  D++ +K K  + E
Sbjct: 127  REKQKGRERERDRGRERERDRDREKERERQTEKDRDGQRETETERERDREREKQKERETE 186

Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +D++R++   +E E+  DR   +RD   +T+++R
Sbjct: 187  RDRDRQRDTEKERERQTDR---ERDRQRKTQTER 217



 Score = 61.2 bits (147), Expect = 1e-08
 Identities = 42/158 (26%), Positives = 75/158 (47%), Gaps = 8/158 (5%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            ++ RR E+  +    R+ Q +++R   R K   +    D    +    ++E E+E +  +
Sbjct: 100  RERRRKEKETNRNRDREKQTEIERDREREKQKGRERERDRGRERERDRDREKERERQTEK 159

Query: 1948 RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKD 2007
             RD  ++ + +R+   E  K KER      DR  D +  R+ R  D++ D+ +    E+ 
Sbjct: 160  DRDGQRETETERERDREREKQKERETERDRDRQRDTEKERE-RQTDRERDRQRKTQTERQ 218

Query: 2008 K------EREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +      ERE  + RE ++DRDR  K+RD     K +R
Sbjct: 219  RETDREGERETDRRRERQRDRDR-GKERDRERDRKEER 255



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 34/148 (22%), Positives = 80/148 (54%), Gaps = 3/148 (2%)

Query: 1894 ERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE-KEWEQESERHRRRDRS 1952
            + R  D    +++++ ++  NR + DR++        +RE+ + +E E++  R R RDR 
Sbjct: 90   KERDRDRKRDRERRRKEKETNRNR-DREKQTEIERDREREKQKGRERERDRGRERERDRD 148

Query: 1953 QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS-RNVDKKPDKPKSEDYEKDKERE 2011
            ++K+R+R++ ++    +E       DR  + +  R++ R+ D++ D  K  + + D+ER+
Sbjct: 149  REKERERQTEKDRDGQRETETERERDREREKQKERETERDRDRQRDTEKERERQTDRERD 208

Query: 2012 KSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            + +  + E+ R+   +    TDR + ++
Sbjct: 209  RQRKTQTERQRETDREGERETDRRRERQ 236



 Score = 49.3 bits (116), Expect = 4e-05
 Identities = 28/110 (25%), Positives = 56/110 (50%), Gaps = 2/110 (1%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH-EKEWEQESERHRRRDRSQDKDRDRKS 1961
            R+ ++Q +R   R + DRQR        + +R  +++ + ++ER R  DR  +++ DR+ 
Sbjct: 175  REREKQKERETERDR-DRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRRR 233

Query: 1962 REEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKERE 2011
              +  +D+ + R    DR  + K  R      ++ +K K E   +DK+R+
Sbjct: 234  ERQRDRDRGKERDRERDRKEERKKERKKERKKERKEKKKEEKRREDKKRK 283



 Score = 42.7 bits (99), Expect = 0.004
 Identities = 32/134 (23%), Positives = 60/134 (44%), Gaps = 22/134 (16%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH---EKEWEQESE 1944
            +D  R +++  +    +D+Q+        + DR+R        +R+R    E E E +  
Sbjct: 173  RDREREKQKERETERDRDRQRDTEKERERQTDRERDRQRKTQTERQRETDREGERETDRR 232

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R R+RDR + K+RDR+   +  + KER +                   ++K ++ + +  
Sbjct: 233  RERQRDRDRGKERDRERDRKEERKKERKK-------------------ERKKERKEKKKE 273

Query: 2005 EKDKEREKSKHREG 2018
            EK +E +K K  EG
Sbjct: 274  EKRREDKKRKWGEG 287



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 10/93 (10%)

Query: 1874 QASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGK-GDRQRFYSDSHHLKR 1932
            Q  R    Q   Q +  R  +R       R+ ++Q DR  +RGK  DR+R        ++
Sbjct: 202  QTDRERDRQRKTQTERQRETDREGERETDRRRERQRDR--DRGKERDRERD-------RK 252

Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEG 1965
            E  +KE ++E ++ R+  + ++K R+ K R+ G
Sbjct: 253  EERKKERKKERKKERKEKKKEEKRREDKKRKWG 285


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
            sapiens]
          Length = 624

 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 42/145 (28%), Positives = 77/145 (53%), Gaps = 15/145 (10%)

Query: 1888 KDIRR---PERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944
            KD RR   P ++ S    R+  +      ++ K  R++   +   +K +  EKE E+E E
Sbjct: 346  KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKEREREKE 404

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R + ++R ++KDRD++  ++  KDKE+          D +  R+  + +K  DK K ++ 
Sbjct: 405  REKEKERGKNKDRDKEREKDREKDKEK----------DREREREKEH-EKDRDKEKEKEQ 453

Query: 2005 EKDKEREKSKHREGEKDRDRYHKDR 2029
            +K+KEREK + +E ++ R +  K R
Sbjct: 454  DKEKEREKDRSKEIDEKRKKDKKSR 478



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 4/129 (3%)

Query: 1914 NRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHK--DK 1969
            N  KG R R +  S S    +    ++  Q   R R  +RS+ + +DR+  +  HK   K
Sbjct: 301  NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360

Query: 1970 ERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDR 2029
             R R     R       +D+R   K+ ++ K +D EK++EREK + +E E+ +++     
Sbjct: 361  SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 420

Query: 2030 DHTDRTKSK 2038
               DR K K
Sbjct: 421  REKDREKDK 429



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 38/143 (26%), Positives = 73/143 (51%), Gaps = 14/143 (9%)

Query: 1895 RRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ 1953
            R H+    RQ D+++   P  +    R+R  S S    R++ +   E+  E+ R +++ +
Sbjct: 336  RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 395

Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013
            +K+R+R+   E  K+KER           GK     +  +K  +K K +D E+++E+E  
Sbjct: 396  EKEREREKERE--KEKER-----------GKNKDRDKEREKDREKDKEKDREREREKEHE 442

Query: 2014 KHREGEKDRDRYHKDRDHTDRTK 2036
            K R+ EK++++  +     DR+K
Sbjct: 443  KDRDKEKEKEQDKEKEREKDRSK 465



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 21/147 (14%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE---------KEWEQESERHRRRDRSQ 1953
            R   +   +  +R K  + +  S SH+  R R +         K+  +  ER + R RS 
Sbjct: 313  RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372

Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013
             +D+ + +RE   K KE+ R+   DR  +       R  +K+ +K K     KD+++E+ 
Sbjct: 373  SRDKRKDTRE---KIKEKERVKEKDREKE-------REREKEREKEKERGKNKDRDKERE 422

Query: 2014 KHREGEKDRDR-YHKDRDH-TDRTKSK 2038
            K RE +K++DR   ++++H  DR K K
Sbjct: 423  KDREKDKEKDREREREKEHEKDRDKEK 449



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 22/168 (13%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  E+       R  +++ DR  ++ K DR+R     H   R++ EKE EQ+ E+ R +D
Sbjct: 405  REKEKERGKNKDRDKEREKDREKDKEK-DREREREKEHEKDRDK-EKEKEQDKEKEREKD 462

Query: 1951 RSQDKD----RDRKSR--EEGHKDKERARLSHGDR-----GTDGKASRDSRNVDKKPDK- 1998
            RS++ D    +D+KSR     +    R+R S  +R      +  ++ R S+ + +K  + 
Sbjct: 463  RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522

Query: 1999 --PKSEDYEKDKEREK-----SKHREGEKDRDRYHKDRDHTDRTKSKR 2039
              P+S + +KDK+REK     S+ RE E+         D   + K ++
Sbjct: 523  PSPRSRN-KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 569



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 24/155 (15%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962
            R+ +++ ++   RGK   +    D    K    +KE ++E ER +  ++ +DK+++++  
Sbjct: 399  REREKEREKEKERGKNKDR----DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 454

Query: 1963 EEGHKDKERARLSHGDRGTDGK---------ASRDSRNVDKKPDKPK----------SED 2003
            +E  ++K+R++     R  D K         ASR SR+  ++  + +          S+ 
Sbjct: 455  KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 514

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
             ++   R  S     +KD+ R  K+RDH    + +
Sbjct: 515  IKRKSSRSPSPRSRNKKDKKR-EKERDHISERRER 548



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)

Query: 1936 EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDK 1994
            E E  + +ER   R RS  + + R S  + H  ++R++  H  R  +   SR   R   K
Sbjct: 294  EPESGKSNERKGGRSRSHTRSKSRSS-SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 352

Query: 1995 KPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHT---DRTKSK 2038
             P K +S+  E+ K R +S  R+  KD     K+++     DR K +
Sbjct: 353  SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 399



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%)

Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQ-RFYSDSHHLKRERHEKEWEQESE 1944
            ++ + R+ +++   P    +  +  R  +R +  R+ R  S S    +    K     S 
Sbjct: 466  EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 525

Query: 1945 RHR-RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003
            R R ++D+ ++K+RD  S     +     R S  DR  DGK       ++K     K ++
Sbjct: 526  RSRNKKDKKREKERDHISERRERERSTSMRKSSNDR--DGK-----EKLEKNSTSLKEKE 578

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDR 2029
            + K+ +   SK  + +KD  R  +++
Sbjct: 579  HNKEPDSSVSKEVD-DKDAPRTEENK 603


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
            sapiens]
          Length = 508

 Score = 68.6 bits (166), Expect = 6e-11
 Identities = 42/145 (28%), Positives = 77/145 (53%), Gaps = 15/145 (10%)

Query: 1888 KDIRR---PERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESE 1944
            KD RR   P ++ S    R+  +      ++ K  R++   +   +K +  EKE E+E E
Sbjct: 230  KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKI-KEKERVKEKDREKEREREKE 288

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R + ++R ++KDRD++  ++  KDKE+          D +  R+  + +K  DK K ++ 
Sbjct: 289  REKEKERGKNKDRDKEREKDREKDKEK----------DREREREKEH-EKDRDKEKEKEQ 337

Query: 2005 EKDKEREKSKHREGEKDRDRYHKDR 2029
            +K+KEREK + +E ++ R +  K R
Sbjct: 338  DKEKEREKDRSKEIDEKRKKDKKSR 362



 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 37/129 (28%), Positives = 61/129 (47%), Gaps = 4/129 (3%)

Query: 1914 NRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHK--DK 1969
            N  KG R R +  S S    +    ++  Q   R R  +RS+ + +DR+  +  HK   K
Sbjct: 185  NERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244

Query: 1970 ERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDR 2029
             R R     R       +D+R   K+ ++ K +D EK++EREK + +E E+ +++     
Sbjct: 245  SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKE 304

Query: 2030 DHTDRTKSK 2038
               DR K K
Sbjct: 305  REKDREKDK 313



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 38/143 (26%), Positives = 73/143 (51%), Gaps = 14/143 (9%)

Query: 1895 RRHSDPWGRQ-DQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQ 1953
            R H+    RQ D+++   P  +    R+R  S S    R++ +   E+  E+ R +++ +
Sbjct: 220  RSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDR 279

Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013
            +K+R+R+   E  K+KER           GK     +  +K  +K K +D E+++E+E  
Sbjct: 280  EKEREREKERE--KEKER-----------GKNKDRDKEREKDREKDKEKDREREREKEHE 326

Query: 2014 KHREGEKDRDRYHKDRDHTDRTK 2036
            K R+ EK++++  +     DR+K
Sbjct: 327  KDRDKEKEKEQDKEKEREKDRSK 349



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 41/147 (27%), Positives = 72/147 (48%), Gaps = 21/147 (14%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHE---------KEWEQESERHRRRDRSQ 1953
            R   +   +  +R K  + +  S SH+  R R +         K+  +  ER + R RS 
Sbjct: 197  RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256

Query: 1954 DKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKS 2013
             +D+ + +RE   K KE+ R+   DR  +       R  +K+ +K K     KD+++E+ 
Sbjct: 257  SRDKRKDTRE---KIKEKERVKEKDREKE-------REREKEREKEKERGKNKDRDKERE 306

Query: 2014 KHREGEKDRDR-YHKDRDH-TDRTKSK 2038
            K RE +K++DR   ++++H  DR K K
Sbjct: 307  KDREKDKEKDREREREKEHEKDRDKEK 333



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 47/168 (27%), Positives = 82/168 (48%), Gaps = 22/168 (13%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  E+       R  +++ DR  ++ K DR+R     H   R++ EKE EQ+ E+ R +D
Sbjct: 289  REKEKERGKNKDRDKEREKDREKDKEK-DREREREKEHEKDRDK-EKEKEQDKEKEREKD 346

Query: 1951 RSQDKD----RDRKSR--EEGHKDKERARLSHGDR-----GTDGKASRDSRNVDKKPDK- 1998
            RS++ D    +D+KSR     +    R+R S  +R      +  ++ R S+ + +K  + 
Sbjct: 347  RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406

Query: 1999 --PKSEDYEKDKEREK-----SKHREGEKDRDRYHKDRDHTDRTKSKR 2039
              P+S + +KDK+REK     S+ RE E+         D   + K ++
Sbjct: 407  PSPRSRN-KKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEK 453



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 34/155 (21%), Positives = 72/155 (46%), Gaps = 24/155 (15%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962
            R+ +++ ++   RGK   +    D    K    +KE ++E ER +  ++ +DK+++++  
Sbjct: 283  REREKEREKEKERGKNKDR----DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQD 338

Query: 1963 EEGHKDKERARLSHGDRGTDGK---------ASRDSRNVDKKPDKPK----------SED 2003
            +E  ++K+R++     R  D K         ASR SR+  ++  + +          S+ 
Sbjct: 339  KEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKT 398

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
             ++   R  S     +KD+ R  K+RDH    + +
Sbjct: 399  IKRKSSRSPSPRSRNKKDKKR-EKERDHISERRER 432



 Score = 45.8 bits (107), Expect = 4e-04
 Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)

Query: 1936 EKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDK 1994
            E E  + +ER   R RS  + + R S  + H  ++R++  H  R  +   SR   R   K
Sbjct: 178  EPESGKSNERKGGRSRSHTRSKSRSS-SKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSK 236

Query: 1995 KPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHT---DRTKSK 2038
             P K +S+  E+ K R +S  R+  KD     K+++     DR K +
Sbjct: 237  SPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKER 283



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 32/146 (21%), Positives = 64/146 (43%), Gaps = 10/146 (6%)

Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQ-RFYSDSHHLKRERHEKEWEQESE 1944
            ++ + R+ +++   P    +  +  R  +R +  R+ R  S S    +    K     S 
Sbjct: 350  EIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSP 409

Query: 1945 RHR-RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003
            R R ++D+ ++K+RD  S     +     R S  DR  DGK       ++K     K ++
Sbjct: 410  RSRNKKDKKREKERDHISERRERERSTSMRKSSNDR--DGK-----EKLEKNSTSLKEKE 462

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDR 2029
            + K+ +   SK  + +KD  R  +++
Sbjct: 463  HNKEPDSSVSKEVD-DKDAPRTEENK 487


>gi|201023339 FIP1 like 1 isoform 2 [Homo sapiens]
          Length = 588

 Score = 67.4 bits (163), Expect = 1e-10
 Identities = 63/231 (27%), Positives = 99/231 (42%), Gaps = 36/231 (15%)

Query: 1812 PPGFPFPGPPNFPPQSMFGFPP---HLPPPLLPPPGFGFAQNPMVPWPPVVHLPGQPQRM 1868
            PP FP   PP   P   F  PP      PPL+PPPG        VP P     PG P   
Sbjct: 342  PPFFPPGAPPTHLPPPPFLPPPPTVSTAPPLIPPPGIPIT----VPPPGFPPPPGAPPPS 397

Query: 1869 MGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSH 1928
            + P  ++    G  + Y  +  R      + P+G      +  P   G         D+ 
Sbjct: 398  LIPTIES----GHSSGYDSRSAR------AFPYG-----NVAFPHLPGSAPSWPSLVDT- 441

Query: 1929 HLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988
                    K+W+  + R + RDR +D+DR+R    +  +D+ER R    +R  D   +  
Sbjct: 442  -------SKQWDYYARREKDRDRERDRDRER----DRDRDRERERTRERERERDHSPTPS 490

Query: 1989 SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
              N D++  + + E  E+  ER ++   + E+ R+R H++++ T R KS R
Sbjct: 491  VFNSDEERYRYR-EYAERGYERHRASREKEERHRERRHREKEET-RHKSSR 539



 Score = 58.2 bits (139), Expect = 8e-08
 Identities = 62/272 (22%), Positives = 115/272 (42%), Gaps = 53/272 (19%)

Query: 1788 SPRTSTNFSPMRPQQPNLQHLKSSPPGFPFPG------PPNFPPQSMFGFPPHLPPPLLP 1841
            +P T     P  P  P +    ++PP  P PG      PP FPP      PP  PPP L 
Sbjct: 349  APPTHLPPPPFLPPPPTVS---TAPPLIPPPGIPITVPPPGFPP------PPGAPPPSLI 399

Query: 1842 P-------PGFGFAQNPMVPWPPVV--HLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRR 1892
            P        G+        P+  V   HLPG        +  + ++    ++Y  ++  R
Sbjct: 400  PTIESGHSSGYDSRSARAFPYGNVAFPHLPGSAPSWPSLVDTSKQW----DYYARREKDR 455

Query: 1893 PERRHSDPWGRQDQQQLDRPFNRGK-GDRQRFYSDSHHL-----KRERHEKEWEQESERH 1946
               R  D   R+  +  DR   R +  +R+R +S +  +     +R R+ +  E+  ERH
Sbjct: 456  DRERDRD---RERDRDRDRERERTRERERERDHSPTPSVFNSDEERYRYREYAERGYERH 512

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            R       ++++ + RE  H++KE  R          K+SR   N  ++ +  + + + +
Sbjct: 513  R-----ASREKEERHRERRHREKEETR---------HKSSRS--NSRRRHESEEGDSHRR 556

Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
             K ++  + +EG++       +++ T+ T ++
Sbjct: 557  HKHKKSKRSKEGKEAGSEPAPEQESTEATPAE 588


>gi|239747174 PREDICTED: hypothetical protein XP_002343931, partial
            [Homo sapiens]
          Length = 213

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 40/151 (26%), Positives = 78/151 (51%), Gaps = 7/151 (4%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-RHEKEWEQESERHRRR 1949
            R  ER       R+ ++Q DR     +G+RQR        +RE   E++ E+E++RH   
Sbjct: 50   RDRERNRERDRDREREKQTDR-----EGERQRERERDRDRQRETERERDKERETDRHTET 104

Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKE 2009
            DR + K ++R+      +++E+ +    +R TD +  R+     ++  +   E   +D+ 
Sbjct: 105  DRERQKQKEREMERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRH 164

Query: 2010 REKSKHREGEKDRDRYHKDRD-HTDRTKSKR 2039
            RE+ + R+ E++R R  K+R+ HTD  + ++
Sbjct: 165  RERERERKRERERKRETKERERHTDMERERQ 195



 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 20/148 (13%)

Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDR 1951
            + E RH+        +Q +R   R + DR+R         R +  K  ++ SER R+RDR
Sbjct: 4    KTEGRHTHTETETMDRQRER---RRETDRER--------DRAKESKTEDRHSERDRQRDR 52

Query: 1952 SQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSED--YEKDK 2008
             ++++RDR    E   D+E      G+R  + +  RD  R  +++ DK +  D   E D+
Sbjct: 53   ERNRERDRDREREKQTDRE------GERQRERERDRDRQRETERERDKERETDRHTETDR 106

Query: 2009 EREKSKHREGEKDRDRYHKDRDHTDRTK 2036
            ER+K K RE E+ RDR  + +    R +
Sbjct: 107  ERQKQKEREMERVRDREREKQKEMGRER 134



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 38/139 (27%), Positives = 75/139 (53%), Gaps = 9/139 (6%)

Query: 1903 RQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSR 1962
            R+ +++ DR  +R K  +    ++  H +R+R +++ E+  ER R R+R +  DR+ + +
Sbjct: 21   RERRRETDRERDRAKESK----TEDRHSERDR-QRDRERNRERDRDREREKQTDREGERQ 75

Query: 1963 EEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE--KDKEREKSKHREGEK 2020
             E  +D++R R +  +R  + +  R +   D++  K K  + E  +D+EREK K    E+
Sbjct: 76   RERERDRDRQRETERERDKERETDRHT-ETDRERQKQKEREMERVRDREREKQKEMGRER 134

Query: 2021 DRDRYHKDRDHTDRTKSKR 2039
              DR   DR+   + + +R
Sbjct: 135  QTDR-ETDRERERQAERER 152



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 42/156 (26%), Positives = 82/156 (52%), Gaps = 7/156 (4%)

Query: 1888 KDIRRPERRHSDPWG-RQDQQQLDRPFNRG---KGDRQRFYSDSHHLKRERHEKEWEQES 1943
            +D  R   + +D  G RQ +++ DR   R    + D++R  +D H       +K+ E+E 
Sbjct: 58   RDRDREREKQTDREGERQRERERDRDRQRETERERDKER-ETDRHTETDRERQKQKEREM 116

Query: 1944 ERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003
            ER R R+R + K+  R+ + +   D+ER R +  +R T  +   + R+ +++ ++ K E 
Sbjct: 117  ERVRDREREKQKEMGRERQTDRETDRERERQAERERETGRERKTEDRHRERERER-KRER 175

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
              K + +E+ +H + E++R R   DR    + +S+R
Sbjct: 176  ERKRETKERERHTDMERERQR-ETDRKRDRQRESER 210



 Score = 55.8 bits (133), Expect = 4e-07
 Identities = 34/136 (25%), Positives = 69/136 (50%), Gaps = 5/136 (3%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER-HEKEWEQESERHRRR 1949
            R  +R+      R  +++ DR     + DR+R       ++R R  E+E ++E  R R+ 
Sbjct: 80   RDRDRQRETERERDKERETDR---HTETDRERQKQKEREMERVRDREREKQKEMGRERQT 136

Query: 1950 DRSQDKDRDRKSREEGHKDKERARLS-HGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDK 2008
            DR  D++R+R++  E    +ER     H +R  + K  R+ +   K+ ++    + E+ +
Sbjct: 137  DRETDRERERQAERERETGRERKTEDRHRERERERKRERERKRETKERERHTDMERERQR 196

Query: 2009 EREKSKHREGEKDRDR 2024
            E ++ + R+ E +R+R
Sbjct: 197  ETDRKRDRQRESERER 212



 Score = 47.0 bits (110), Expect = 2e-04
 Identities = 30/111 (27%), Positives = 58/111 (52%), Gaps = 12/111 (10%)

Query: 1940 EQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG-DRGTDGKASRDSRNVDKKPDK 1998
            E ++E       ++  DR R+ R E  ++++RA+ S   DR ++    RD R  +++ D+
Sbjct: 2    ESKTEGRHTHTETETMDRQRERRRETDRERDRAKESKTEDRHSERDRQRD-RERNRERDR 60

Query: 1999 PKSEDYEKDKEREKSKHREGEKDRDR-YHKDRD---------HTDRTKSKR 2039
             +  + + D+E E+ + RE ++DR R   ++RD          TDR + K+
Sbjct: 61   DREREKQTDREGERQRERERDRDRQRETERERDKERETDRHTETDRERQKQ 111



 Score = 45.1 bits (105), Expect = 7e-04
 Identities = 35/122 (28%), Positives = 57/122 (46%), Gaps = 23/122 (18%)

Query: 1886 QVKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945
            +++ +R  ER      GR  ++Q DR  +R   +R+R         RER  ++  +E ER
Sbjct: 115  EMERVRDREREKQKEMGR--ERQTDRETDR---ERERQAERERETGRERKTEDRHRERER 169

Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
             R+R+R  ++ R+ K RE  H D ER R                R  D+K D+ +  + E
Sbjct: 170  ERKRER--ERKRETKERER-HTDMERER---------------QRETDRKRDRQRESERE 211

Query: 2006 KD 2007
            +D
Sbjct: 212  RD 213


>gi|239747891 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 202

 Score = 65.9 bits (159), Expect = 4e-10
 Identities = 39/136 (28%), Positives = 74/136 (54%), Gaps = 11/136 (8%)

Query: 1906 QQQLDRPFNRGKG-DRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREE 1964
            Q++  R  +RGK  +R+R         R+R  +   +   RHR+RDR +++DR     +E
Sbjct: 4    QRERKRETDRGKETERER--------DRQRERENQTERENRHRQRDRHRERDRQTDREKE 55

Query: 1965 GHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDR 2024
              + KER R    +R T+ +  R  R   ++ ++ +  D E+DK+R++ + RE +++R+R
Sbjct: 56   RERQKERDRQRQRERETERETER-QRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114

Query: 2025 YHK-DRDHTDRTKSKR 2039
              K  R+   +T+ +R
Sbjct: 115  NRKGGRERDKQTERER 130



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 41/171 (23%), Positives = 83/171 (48%), Gaps = 36/171 (21%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERH---------EKEWEQ 1941
            R+ ER+     G++ +++ DR   R     +    ++ H +R+RH         EKE E+
Sbjct: 3    RQRERKRETDRGKETERERDRQRERENQTER----ENRHRQRDRHRERDRQTDREKERER 58

Query: 1942 ESER--------------HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASR 1987
            + ER               R+R+R + ++R R++  E  KD++R R    DR        
Sbjct: 59   QKERDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDR-------- 110

Query: 1988 DSRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
             +R  ++K  + + +  E++++RE+ + R+ E++R R  + +  TDR + +
Sbjct: 111  -NRERNRKGGRERDKQTERERDRERERQRQRERERQRQRERKRETDRERQR 160



 Score = 58.5 bits (140), Expect = 6e-08
 Identities = 42/169 (24%), Positives = 83/169 (49%), Gaps = 19/169 (11%)

Query: 1882 QNFYQVKDIRRPERRHSD-PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE 1940
            +N ++ +D  R   R +D    R+ Q++ DR        RQR        +R+R E++ +
Sbjct: 34   ENRHRQRDRHRERDRQTDREKERERQKERDR-------QRQRERETERETERQR-ERQRQ 85

Query: 1941 QESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD---SRNVDKKPD 1997
            +E +R   R+R +D+DR+RK   + ++++ R      D+ T+ +  R+    R  +++  
Sbjct: 86   RERKRQTDRERDKDRDRERKRETDRNRERNRKGGRERDKQTERERDRERERQRQRERERQ 145

Query: 1998 KPKSEDYEKDKER-------EKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            + +    E D+ER       E+ K R+ E+ ++R  K ++   R   KR
Sbjct: 146  RQRERKRETDRERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKR 194



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 37/131 (28%), Positives = 64/131 (48%), Gaps = 8/131 (6%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  ER+      R+ ++Q DR  ++   DR R         RER+ K   +E ++   R+
Sbjct: 74   RETERQRERQRQRERKRQTDRERDK---DRDRERKRETDRNRERNRKGG-RERDKQTERE 129

Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPD--KPKSEDYEKDK 2008
            R ++++R R+   E  + +ER R    DR     A R+ R  ++K +  K + E  +++K
Sbjct: 130  RDRERERQRQRERERQRQRERKR--ETDRERQRWAEREERKKERKKERKKERKEKKKEEK 187

Query: 2009 EREKSKHREGE 2019
             RE  K + GE
Sbjct: 188  RREDKKRKWGE 198



 Score = 50.4 bits (119), Expect = 2e-05
 Identities = 29/113 (25%), Positives = 57/113 (50%), Gaps = 14/113 (12%)

Query: 1940 EQESERHRRRDRSQD--KDRDRKSREEGHKDKE-----RARLSHGDRGTDGKASRD---- 1988
            E++ ER R  DR ++  ++RDR+   E   ++E     R R    DR TD +  R+    
Sbjct: 2    ERQRERKRETDRGKETERERDRQRERENQTERENRHRQRDRHRERDRQTDREKERERQKE 61

Query: 1989 ---SRNVDKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSK 2038
                R  +++ ++      E+ ++RE+ +  + E+D+DR  + +  TDR + +
Sbjct: 62   RDRQRQRERETERETERQRERQRQRERKRQTDRERDKDRDRERKRETDRNRER 114



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 20/93 (21%), Positives = 51/93 (54%), Gaps = 12/93 (12%)

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            R+R+R ++ DR +++  E  + +ER          + +  R++R+  ++ D+ +  D + 
Sbjct: 3    RQRERKRETDRGKETERERDRQRER----------ENQTERENRH--RQRDRHRERDRQT 50

Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            D+E+E+ + +E ++ R R  +    T+R + ++
Sbjct: 51   DREKERERQKERDRQRQRERETERETERQRERQ 83



 Score = 39.3 bits (90), Expect = 0.040
 Identities = 26/103 (25%), Positives = 47/103 (45%), Gaps = 14/103 (13%)

Query: 1888 KDIRRPERRHSD-------PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRER------ 1934
            KD  R  +R +D         GR+  +Q +R  +R + +RQR        +RER      
Sbjct: 98   KDRDRERKRETDRNRERNRKGGRERDKQTERERDRER-ERQRQRERERQRQRERKRETDR 156

Query: 1935 HEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHG 1977
              + W +  ER + R + + K+R  K +EE  ++ ++ +   G
Sbjct: 157  ERQRWAEREERKKERKKERKKERKEKKKEEKRREDKKRKWGEG 199


>gi|155030236 ribonuclease III, nuclear isoform 2 [Homo sapiens]
          Length = 1337

 Score = 65.5 bits (158), Expect = 5e-10
 Identities = 71/256 (27%), Positives = 103/256 (40%), Gaps = 45/256 (17%)

Query: 1795 FSPMRPQQP--NLQHLKSSPPG---FPF----------PGPPNFPPQSMFGFPPHLPPPL 1839
            F PM P  P  N   +  +PPG   FPF          P PP  P Q  + +PP      
Sbjct: 117  FPPMPPPMPCPNNPPVPGAPPGQGTFPFMMPPPSMPHPPPPPVMPQQVNYQYPPGYSHHN 176

Query: 1840 LPPPGFGFAQNPMVPWPPVVHLPGQPQ-RMMGPL---SQASRYIGPQNFYQVKDIRRPER 1895
             PPP F   QN    + P  +    P  R + P       S    P+      D R  + 
Sbjct: 177  FPPPSFNSFQNNPSSFLPSANNSSSPHFRHLPPYPLPKAPSERRSPERLKHYDDHRHRDH 236

Query: 1896 RHSDPWGRQDQQQ-LDRPFNRGKGDRQRF-------YSDSHHLKRER-HEKEWEQESERH 1946
             H    GR ++ + LDR       DR+R        Y       R R +E+  E+E ERH
Sbjct: 237  SH----GRGERHRSLDRRERGRSPDRRRQDSRYRSDYDRGRTPSRHRSYERSRERERERH 292

Query: 1947 RRRD--------RSQDKDRDRKSREEGHKDKERARL-SHGDRGTDGKASRDSRNV----D 1993
            R RD        RS  K+  R       ++K+RAR     DR +D ++S   +N     +
Sbjct: 293  RHRDNRRSPSLERSYKKEYKRSGSRSPSREKKRARWEEEKDRWSDNQSSGKDKNYTSIKE 352

Query: 1994 KKPDKPKSEDYEKDKE 2009
            K+P++   +  E+++E
Sbjct: 353  KEPEETMPDKNEEEEE 368



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 66/244 (27%), Positives = 90/244 (36%), Gaps = 61/244 (25%)

Query: 1797 PMRPQQPNLQHLKSSPPGFPFPGPPNFPPQSMFGFPPHLPPPLLPP-----PGFGF---- 1847
            P+RP  PN Q         PFP PP FPP      PP +P P  PP     PG G     
Sbjct: 97   PIRPPFPNHQMRH------PFPVPPCFPPM-----PPPMPCPNNPPVPGAPPGQGTFPFM 145

Query: 1848 ---AQNPMVPWPPVV-------HLPGQPQRMMGPLSQASRYIGPQNFY-QVKDIRRPERR 1896
                  P  P PPV+       + PG       P S  S    P +F     +   P  R
Sbjct: 146  MPPPSMPHPPPPPVMPQQVNYQYPPGYSHHNFPPPSFNSFQNNPSSFLPSANNSSSPHFR 205

Query: 1897 HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDKD 1956
            H  P+          P  R   +R + Y D       RH        ERHR  DR     
Sbjct: 206  HLPPYPLPKA-----PSERRSPERLKHYDD------HRHRDHSHGRGERHRSLDR----- 249

Query: 1957 RDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKEREKSKHR 2016
            R+R    +  +   R R  + DRG             + P + +S +  +++ERE+ +HR
Sbjct: 250  RERGRSPDRRRQDSRYRSDY-DRG-------------RTPSRHRSYERSRERERERHRHR 295

Query: 2017 EGEK 2020
            +  +
Sbjct: 296  DNRR 299


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 56/209 (26%), Positives = 87/209 (41%), Gaps = 29/209 (13%)

Query: 1854 PWPPVVHLPGQPQRMMGPLSQASRYIGPQNFYQVKDIRRPERRHSDPWGRQDQQQLDRPF 1913
            PW P+V   G  ++            GP    +  + R  +R        QD+++ D+  
Sbjct: 1168 PWRPLVKPGGWREKEKA----REESWGPPRESRPSEEREWDREKERDRDNQDREENDKDP 1223

Query: 1914 NRGKGDRQRFYSDSHHLKRERHEKEWE----QESERHRRRDRSQDKDRDRKSRE-EGHKD 1968
             R + DR+R        +R R E  W     +ES   R   R  D+DRD + RE +  +D
Sbjct: 1224 ERER-DRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRD 1282

Query: 1969 KERARLSHGDRGTDGKASRDSRNV--------DKKPDKPKSED---------YEKDKERE 2011
                R    DR   G   R  R          D+K D+ +  D           +D+ER+
Sbjct: 1283 LRERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERD 1342

Query: 2012 KSKHREGEKDRD--RYHKDRDHTDRTKSK 2038
            + + REGEK++   R  KDR+   RTK++
Sbjct: 1343 RDREREGEKEKASWRAEKDRESLRRTKNE 1371



 Score = 41.2 bits (95), Expect = 0.010
 Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 17/170 (10%)

Query: 1882 QNFYQVK----DIRRPERRHSDPWGRQDQQQLDR--PFNRGKGDRQRFYSDSHHLK---- 1931
            Q+ Y+ K    + R  E RH+    R+ Q++ +R   + R K + ++  ++   LK    
Sbjct: 769  QSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREE 828

Query: 1932 RERHEKEWEQES--ERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS 1989
            RER E+   +E   E   R  + ++ +R ++ RE   +++ER R      G    + +DS
Sbjct: 829  RERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRLGDSSLSRKDS 888

Query: 1990 RNVDKKPDKPKSEDYEKDKE-----REKSKHREGEKDRDRYHKDRDHTDR 2034
            R  D+  +    +  E D E      EK   R   +D DR H+  +   R
Sbjct: 889  RWGDRDSEGTWRKGPEADSEWRRGPPEKEWRRGEGRDEDRSHRRDEERPR 938



 Score = 35.4 bits (80), Expect = 0.57
 Identities = 36/160 (22%), Positives = 66/160 (41%), Gaps = 10/160 (6%)

Query: 1889 DIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR- 1947
            D R P R   D  G +     DR   RG  D +  + ++   +  R   E ++   R+  
Sbjct: 1085 DDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRIPRRGAEDDRGPWRNMD 1144

Query: 1948 --RRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
              R  R  D DR  +  ++      R  +  G      KA  +S    ++    +  +++
Sbjct: 1145 DDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGPPRESRPSEEREWD 1204

Query: 2006 KDKEREKSKH------REGEKDRDRYHKDRDHTDRTKSKR 2039
            ++KER++         ++ E++RDR  +D D  DR +  R
Sbjct: 1205 REKERDRDNQDREENDKDPERERDR-ERDVDREDRFRRPR 1243



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 36/145 (24%), Positives = 56/145 (38%), Gaps = 28/145 (19%)

Query: 1889 DIRRPERRHSD---PWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER 1945
            D R P R   D   PW   D  +L R   R   DR     D       R   +     E+
Sbjct: 1125 DDRIPRRGAEDDRGPWRNMDDDRLSR---RADDDRFPRRGDDSRPGPWRPLVKPGGWREK 1181

Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
             + R+ S    R+ +  EE   D+E+ R          + ++D    DK P++      E
Sbjct: 1182 EKAREESWGPPRESRPSEEREWDREKER---------DRDNQDREENDKDPER------E 1226

Query: 2006 KDKEREKSKHREGEKDRDRYHKDRD 2030
            +D+ER+  +        DR+ + RD
Sbjct: 1227 RDRERDVDR-------EDRFRRPRD 1244



 Score = 33.1 bits (74), Expect = 2.8
 Identities = 38/154 (24%), Positives = 61/154 (39%), Gaps = 16/154 (10%)

Query: 1891 RRPERRHSDP-WGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRR 1949
            R  ERR  D    R+D +  DR     +G  ++        +R   EKEW +   R    
Sbjct: 872  REEERRLGDSSLSRKDSRWGDRD---SEGTWRKGPEADSEWRRGPPEKEWRRGEGRD--E 926

Query: 1950 DRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDKE 2009
            DRS  +D +R  R    +D+E +     DR    +   D R   + P++ +      D +
Sbjct: 927  DRSHRRDEERPRRLGDDEDREPSLRPDDDR-VPRRGMDDDRGPRRGPEEDRFSRRGADDD 985

Query: 2010 R--------EKSKHREGEKDRDRY-HKDRDHTDR 2034
            R        ++   R  ++DR  + H D D   R
Sbjct: 986  RPSWRNTDDDRPPRRIADEDRGNWRHADDDRPPR 1019


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 63.2 bits (152), Expect = 3e-09
 Identities = 45/156 (28%), Positives = 79/156 (50%), Gaps = 9/156 (5%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQES----ERH 1946
            R+ ERR  +   R+ +++ +R   RGK ++++        +RER  KE E++     E+ 
Sbjct: 36   RKKERREREK--RKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKE 93

Query: 1947 RRRDRSQDKDRDRK--SREEGHKDKER-ARLSHGDRGTDGKASRDSRNVDKKPDKPKSED 2003
            RR+ + + K R+RK   R E  K KER  R     +  + K  +  +   +K  K + E 
Sbjct: 94   RRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKER 153

Query: 2004 YEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
             +++++R+K K  E EK R+R  K+R      K +R
Sbjct: 154  GKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 34/140 (24%), Positives = 75/140 (53%), Gaps = 15/140 (10%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            ++ +R ERR  +   R+ +++      RG+ +R++        K+ER E+E E +  R R
Sbjct: 82   REKQRKERREKERRKRKKEKKKRERKQRGRRERKK--------KKERKERERENKQRRER 133

Query: 1948 RRDRSQDKDR---DRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            +R + + K R    ++ +E G ++++R +    +R    +  R+    ++K ++ + E  
Sbjct: 134  KRKKRRKKKRRKERKREKERGKRERKRKKRKKEER----EKKRERNRKERKKERERKERR 189

Query: 2005 EKDKEREKSKHREGEKDRDR 2024
            E+ KER+K + ++ E+ +DR
Sbjct: 190  ERKKERKKERRKKKERKKDR 209



 Score = 57.4 bits (137), Expect = 1e-07
 Identities = 31/115 (26%), Positives = 66/115 (57%), Gaps = 7/115 (6%)

Query: 1929 HLKRERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD 1988
            H+ +   ++E E++ ER  R  R ++++++RK RE G K+K++ +    +RG + +  R 
Sbjct: 24   HISKPCTQRESERKKERREREKRKREREKERK-RERGKKEKKKRK--KRERGKERERKRK 80

Query: 1989 SRNVDKK----PDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
             R   +K     ++ K +  +K +ER++   RE +K ++R  ++R++  R + KR
Sbjct: 81   EREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKR 135



 Score = 55.5 bits (132), Expect = 5e-07
 Identities = 36/153 (23%), Positives = 74/153 (48%), Gaps = 2/153 (1%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-H 1946
            K  R+   R  +   ++ +++  R   R K  R+R        +++R  +E +++ ER  
Sbjct: 63   KKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            R R+  Q ++R RK R +  + KER R     +    +  R     +KK ++ + E  +K
Sbjct: 123  RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE-RKK 181

Query: 2007 DKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            ++ER++ + R+ E+ ++R  K     DR   ++
Sbjct: 182  ERERKERRERKKERKKERRKKKERKKDRKTDRQ 214



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 14/151 (9%)

Query: 1898 SDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQD-KD 1956
            S P  +++ ++      R K  R+R        KRER +KE ++  +R R ++R +  K+
Sbjct: 26   SKPCTQRESERKKERREREKRKRER----EKERKRERGKKEKKKRKKRERGKERERKRKE 81

Query: 1957 RDRKSREEGHKD--------KERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEKDK 2008
            R+++ +E   K+        K+R R   G R    K  R  R  + K  + +     + K
Sbjct: 82   REKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKK 141

Query: 2009 EREKSKHREGEK-DRDRYHKDRDHTDRTKSK 2038
            +R K + RE E+  R+R  K R   +R K +
Sbjct: 142  KRRKERKREKERGKRERKRKKRKKEEREKKR 172



 Score = 51.6 bits (122), Expect = 8e-06
 Identities = 31/102 (30%), Positives = 56/102 (54%), Gaps = 8/102 (7%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFY--SDSHHLKRERHEKEWEQESERHRR 1948
            +R ER+      ++ +++  R   RGK +R+R     +    KRER+ KE ++E ER  R
Sbjct: 129  QRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKER 188

Query: 1949 RDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSR 1990
            R+R +++ ++R+ ++E  KD++       DR TD +  R  R
Sbjct: 189  RERKKERKKERRKKKERKKDRKT------DRQTDSQVFRPLR 224



 Score = 43.5 bits (101), Expect = 0.002
 Identities = 29/102 (28%), Positives = 55/102 (53%), Gaps = 5/102 (4%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            ++ ER+  +   +Q +++  R   R K  R+    +    KRER  K+ ++E ER ++R+
Sbjct: 116  KKKERKERERENKQRRER-KRKKRRKKKRRKERKREKERGKRERKRKKRKKE-EREKKRE 173

Query: 1951 RS---QDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDS 1989
            R+   + K+R+RK R E  K++++ R    +R  D K  R +
Sbjct: 174  RNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215


>gi|52426743 cisplatin resistance-associated overexpressed protein
            [Homo sapiens]
          Length = 432

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 28/107 (26%), Positives = 58/107 (54%)

Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNV 1992
            ER +KE ++  ER + R+R +++   ++ REE  ++KERAR     + +  ++   SR  
Sbjct: 245  ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304

Query: 1993 DKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            D++  + +     + +ER +S+ R+  + R     +R H  R++ +R
Sbjct: 305  DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 11/157 (7%)

Query: 1887 VKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERH 1946
            V++++   R+ ++   R ++ + ++   R + +++R   +    +RER  +  E+E E+ 
Sbjct: 227  VEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKER---EREREERERKRRREEEEREKE 282

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            R RDR + K    +SR        R   S   + +  +  R SR+ D++  + +S D  +
Sbjct: 283  RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSE 340

Query: 2007 DKEREKSKHREGEKDRDR-----YHKDRDHTDRTKSK 2038
             K R +S+ R   K RDR       K RD     KSK
Sbjct: 341  RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 21/160 (13%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-- 1945
            K    P+R       +Q++++ ++   R + +R+R        KR R E+E E+E  R  
Sbjct: 236  KRTEEPDRDERLKKEKQEREEREKEREREREERER--------KRRREEEEREKERARDR 287

Query: 1946 -HRRRDRSQDKDRDRK-----SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999
              R+R RS+ +   R      SR   HK + R+R     R  D + SR S +  ++  + 
Sbjct: 288  ERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRSRDRRRSR-SHDRSERKHRS 345

Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +S D  + K R++  ++   K RDR   ++D   + K KR
Sbjct: 346  RSRDRRRSKSRDRKSYKHRSKSRDR---EQDRKSKEKEKR 382



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 6/138 (4%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-----RHEKEWEQESER 1945
            R  ER   +   R+++++ ++   R +  R+R  S S H  R         ++ ++   R
Sbjct: 261  REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320

Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDY 2004
             RRR RS+D+ R R       K + R+R     +  D K+ +  S++ D++ D+   E  
Sbjct: 321  ERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380

Query: 2005 EKDKEREKSKHREGEKDR 2022
            ++  + +KS  + G +++
Sbjct: 381  KRGSDDKKSSVKSGSREK 398



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 16/143 (11%)

Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERH 1946
            R  R+ S    R   +  DR  +R +       R+R  S S   +R R     E++  R 
Sbjct: 287  RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK-HRS 345

Query: 1947 RRRDRSQDKDRDRKS---------REEGHKDKERARLSHGDRGTDGKA-SRDSRNVDKKP 1996
            R RDR + K RDRKS         RE+  K KE+ +    D+ +  K+ SR+ ++ D   
Sbjct: 346  RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405

Query: 1997 DKPKSEDYEKDKEREKSKHREGE 2019
            +  +S+   +     +    EG+
Sbjct: 406  ESKESDTKNEVNGTSEDIKSEGD 428



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 28/128 (21%), Positives = 53/128 (41%), Gaps = 10/128 (7%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  + + S    R+  +  DR  +R     +R +      +R    ++ +    R + RD
Sbjct: 310  RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369

Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK-----SEDYE 2005
            R Q  DR  K +E+   D +++ +  G R    K S D+    K+ D        SED +
Sbjct: 370  REQ--DRKSKEKEKRGSDDKKSSVKSGSR---EKQSEDTNTESKESDTKNEVNGTSEDIK 424

Query: 2006 KDKEREKS 2013
             + + + +
Sbjct: 425  SEGDTQSN 432


>gi|19923485 cisplatin resistance-associated overexpressed protein
            [Homo sapiens]
          Length = 432

 Score = 62.8 bits (151), Expect = 3e-09
 Identities = 28/107 (26%), Positives = 58/107 (54%)

Query: 1933 ERHEKEWEQESERHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNV 1992
            ER +KE ++  ER + R+R +++   ++ REE  ++KERAR     + +  ++   SR  
Sbjct: 245  ERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS 304

Query: 1993 DKKPDKPKSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            D++  + +     + +ER +S+ R+  + R     +R H  R++ +R
Sbjct: 305  DRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRR 351



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 40/157 (25%), Positives = 74/157 (47%), Gaps = 11/157 (7%)

Query: 1887 VKDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERH 1946
            V++++   R+ ++   R ++ + ++   R + +++R   +    +RER  +  E+E E+ 
Sbjct: 227  VEELKEKLRKRTEEPDRDERLKKEKQ-EREEREKER---EREREERERKRRREEEEREKE 282

Query: 1947 RRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYEK 2006
            R RDR + K    +SR        R   S   + +  +  R SR+ D++  + +S D  +
Sbjct: 283  RARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRR--RSRSHDRSE 340

Query: 2007 DKEREKSKHREGEKDRDR-----YHKDRDHTDRTKSK 2038
             K R +S+ R   K RDR       K RD     KSK
Sbjct: 341  RKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSK 377



 Score = 55.1 bits (131), Expect = 7e-07
 Identities = 43/160 (26%), Positives = 75/160 (46%), Gaps = 21/160 (13%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESER-- 1945
            K    P+R       +Q++++ ++   R + +R+R        KR R E+E E+E  R  
Sbjct: 236  KRTEEPDRDERLKKEKQEREEREKEREREREERER--------KRRREEEEREKERARDR 287

Query: 1946 -HRRRDRSQDKDRDRK-----SREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKP 1999
              R+R RS+ +   R      SR   HK + R+R     R  D + SR S +  ++  + 
Sbjct: 288  ERRKRSRSRSRHSSRTSDRRCSRSRDHK-RSRSRERRRSRSRDRRRSR-SHDRSERKHRS 345

Query: 2000 KSEDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            +S D  + K R++  ++   K RDR   ++D   + K KR
Sbjct: 346  RSRDRRRSKSRDRKSYKHRSKSRDR---EQDRKSKEKEKR 382



 Score = 51.2 bits (121), Expect = 1e-05
 Identities = 32/138 (23%), Positives = 66/138 (47%), Gaps = 6/138 (4%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRE-----RHEKEWEQESER 1945
            R  ER   +   R+++++ ++   R +  R+R  S S H  R         ++ ++   R
Sbjct: 261  REREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSR 320

Query: 1946 HRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRD-SRNVDKKPDKPKSEDY 2004
             RRR RS+D+ R R       K + R+R     +  D K+ +  S++ D++ D+   E  
Sbjct: 321  ERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKE 380

Query: 2005 EKDKEREKSKHREGEKDR 2022
            ++  + +KS  + G +++
Sbjct: 381  KRGSDDKKSSVKSGSREK 398



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 38/143 (26%), Positives = 62/143 (43%), Gaps = 16/143 (11%)

Query: 1892 RPERRHSDPWGRQDQQQLDRPFNRGKG-----DRQRFYSDSHHLKRERHEKEWEQESERH 1946
            R  R+ S    R   +  DR  +R +       R+R  S S   +R R     E++  R 
Sbjct: 287  RERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERK-HRS 345

Query: 1947 RRRDRSQDKDRDRKS---------REEGHKDKERARLSHGDRGTDGKA-SRDSRNVDKKP 1996
            R RDR + K RDRKS         RE+  K KE+ +    D+ +  K+ SR+ ++ D   
Sbjct: 346  RSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSEDTNT 405

Query: 1997 DKPKSEDYEKDKEREKSKHREGE 2019
            +  +S+   +     +    EG+
Sbjct: 406  ESKESDTKNEVNGTSEDIKSEGD 428



 Score = 33.5 bits (75), Expect = 2.2
 Identities = 28/128 (21%), Positives = 53/128 (41%), Gaps = 10/128 (7%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRD 1950
            R  + + S    R+  +  DR  +R     +R +      +R    ++ +    R + RD
Sbjct: 310  RSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRD 369

Query: 1951 RSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPK-----SEDYE 2005
            R Q  DR  K +E+   D +++ +  G R    K S D+    K+ D        SED +
Sbjct: 370  REQ--DRKSKEKEKRGSDDKKSSVKSGSR---EKQSEDTNTESKESDTKNEVNGTSEDIK 424

Query: 2006 KDKEREKS 2013
             + + + +
Sbjct: 425  SEGDTQSN 432


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 62.4 bits (150), Expect = 4e-09
 Identities = 43/159 (27%), Positives = 84/159 (52%), Gaps = 12/159 (7%)

Query: 1889 DIRRPERR-HSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWE---QESE 1944
            +IR  ER   +   G+++++   +   R +  R+R        +R + EK+ E   +E E
Sbjct: 37   EIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERE 96

Query: 1945 RHRRRDRSQDKDRDRKSREEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDY 2004
            R +RR   ++K+ + K + +  + KER R S    G + +   + +  ++K  + K E+ 
Sbjct: 97   RKKRRREKENKEGEEKEKRKKKEKKERGRTS--KEGKERERKEERKREERKERERKKEER 154

Query: 2005 EKDKEREKSKHRE----GEKDRDRYHKDRDHTDRTKSKR 2039
            EK++ER++ K RE    GEK+ +R  K+++  +R K +R
Sbjct: 155  EKERERKERKKRERKQVGEKEEER--KEKERKERKKRER 191



 Score = 60.1 bits (144), Expect = 2e-08
 Identities = 43/158 (27%), Positives = 82/158 (51%), Gaps = 15/158 (9%)

Query: 1891 RRPERRHSDPWGRQDQQQLDRPFNRGK----GDRQRFYSDSHHLKRERHEKEWEQESERH 1946
            R+ ERR  +   R+ +++ +R   RGK    G+R++   +    K+ R EKE  +E E  
Sbjct: 59   RKKERREREK--RKREREKERKRERGKKEKKGERKK---EERERKKRRREKE-NKEGEEK 112

Query: 1947 RRRDRSQDKDRDRKSRE--EGHKDKERARLSHGDR---GTDGKASRDSRNVDKKPDKPKS 2001
             +R + + K+R R S+E  E  + +ER R    +R     + +  R+ +   K+  K   
Sbjct: 113  EKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVG 172

Query: 2002 EDYEKDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            E  E+ KE+E+ + ++ E++R    K+R+  +R + K+
Sbjct: 173  EKEEERKEKERKERKKRERNRKERKKERERKERRERKK 210



 Score = 59.3 bits (142), Expect = 4e-08
 Identities = 36/154 (23%), Positives = 74/154 (48%), Gaps = 12/154 (7%)

Query: 1898 SDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHRRRDRSQDK-- 1955
            + P  + + ++ +R     K  ++   S+    +RER +++ E+E ER R R + + K  
Sbjct: 30   TQPGWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGE 89

Query: 1956 ----DRDRKSR------EEGHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKSEDYE 2005
                +R+RK R      +EG + ++R +    +RG   K  ++    +++  + + E   
Sbjct: 90   RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149

Query: 2006 KDKEREKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            K +EREK + R+  K R+R        +R + +R
Sbjct: 150  KKEEREKERERKERKKRERKQVGEKEEERKEKER 183



 Score = 54.3 bits (129), Expect = 1e-06
 Identities = 36/162 (22%), Positives = 79/162 (48%), Gaps = 18/162 (11%)

Query: 1888 KDIRRPERRHSDPWGRQDQQQLDRPFNRGKGDRQRFYSDSHHLKRERHEKEWEQESERHR 1947
            K+ R  ++R  +   ++ +++  R   + K  ++R  +     +RER E+   +E +   
Sbjct: 92   KEERERKKRRREKENKEGEEKEKR---KKKEKKERGRTSKEGKERERKEERKREERKERE 148

Query: 1948 RRDRSQDKDRDRKSREE------GHKDKERARLSHGDRGTDGKASRDSRNVDKKPDKPKS 2001
            R+   ++K+R+RK R++      G K++ER      +R       R+    ++K ++ + 
Sbjct: 149  RKKEEREKERERKERKKRERKQVGEKEEERKEKERKER-----KKRERNRKERKKERERK 203

Query: 2002 EDYEKDKER----EKSKHREGEKDRDRYHKDRDHTDRTKSKR 2039
            E  E+ KER    E+ K R+ ++  +   K+R   +R + K+
Sbjct: 204  ERRERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245



 Score = 32.7 bits (73), Expect = 3.7
 Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 1027 RRRENRHTIEMIEKEQREVERRPITKITHKGEIEIESDAPMKEQEAAMEIQEPAANKSLE 1086
            + RE+    E  E+E+R+ ER    K   +G+ E + +   +E+E     +E    +  E
Sbjct: 53   KERESERKKERREREKRKREREKERK-RERGKKEKKGERKKEERERKKRRREKENKEGEE 111

Query: 1087 KPEGSEKQKEEVDSMSKDTTSQHRQ 1111
            K +  +K+K+E    SK+   + R+
Sbjct: 112  KEKRKKKEKKERGRTSKEGKERERK 136


>gi|38505156 transcription elongation factor A protein 2 isoform b
            [Homo sapiens]
          Length = 272

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%)

Query: 930  SVRHSLKDILMKRL-TDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNL 988
            +VR+  +++L   L TD +         +++ +IE+ +F    +TD KYKN+ RS + NL
Sbjct: 110  AVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNL 169

Query: 989  KDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035
            KD KN  L + VL G +TP  +  M+ EE+AS EL   R+   +  I
Sbjct: 170  KDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAI 216


>gi|4507385 transcription elongation factor A protein 2 isoform a
            [Homo sapiens]
          Length = 299

 Score = 62.0 bits (149), Expect = 6e-09
 Identities = 38/107 (35%), Positives = 60/107 (56%), Gaps = 1/107 (0%)

Query: 930  SVRHSLKDILMKRL-TDSNLKVPEEKAAKVATKIEKELFSFFRDTDAKYKNKYRSLMFNL 988
            +VR+  +++L   L TD +         +++ +IE+ +F    +TD KYKN+ RS + NL
Sbjct: 137  AVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFRDVGNTDMKYKNRVRSRISNL 196

Query: 989  KDPKNNILFKKVLKGEVTPDHLIRMSPEELASKELAAWRRRENRHTI 1035
            KD KN  L + VL G +TP  +  M+ EE+AS EL   R+   +  I
Sbjct: 197  KDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKEAI 243


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,393,349
Number of Sequences: 37866
Number of extensions: 4533125
Number of successful extensions: 32919
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 305
Number of HSP's successfully gapped in prelim test: 878
Number of HSP's that attempted gapping in prelim test: 19704
Number of HSP's gapped (non-prelim): 8766
length of query: 2039
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1921
effective length of database: 13,779,330
effective search space: 26470092930
effective search space used: 26470092930
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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