Guide to the Human Genome
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Search of human proteins with 7662002

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7662002 ER degradation enhancer, mannosidase alpha-like 1
[Homo sapiens]
         (657 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Ho...  1358   0.0  
gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [...   384   e-106
gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i...   355   7e-98
gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i...   328   7e-90
gi|218749883 alpha 1,2-mannosidase [Homo sapiens]                     188   2e-47
gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]      175   1e-43
gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]     164   2e-40
gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]      157   2e-38
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    45   2e-04
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    39   0.015
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    39   0.015
gi|119508426 alpha 3 type IX collagen [Homo sapiens]                   38   0.026
gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]         37   0.058
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ...    37   0.058
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ...    37   0.058
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       37   0.075
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]          37   0.075
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      36   0.098
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      36   0.098
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     36   0.13 
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    36   0.13 
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    36   0.13 
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    36   0.13 
gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]                35   0.22 
gi|33286446 opioid growth factor receptor [Homo sapiens]               35   0.29 
gi|118498339 EMI domain containing 2 [Homo sapiens]                    35   0.29 
gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]            34   0.37 
gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]           34   0.37 
gi|38373671 SEC24-related protein C [Homo sapiens]                     34   0.37 
gi|38373669 SEC24-related protein C [Homo sapiens]                     34   0.37 

>gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo
           sapiens]
          Length = 657

 Score = 1358 bits (3515), Expect = 0.0
 Identities = 657/657 (100%), Positives = 657/657 (100%)

Query: 1   MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV 60
           MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV
Sbjct: 1   MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV 60

Query: 61  GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG 120
           GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG
Sbjct: 61  GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG 120

Query: 121 AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG 180
           AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG
Sbjct: 121 AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG 180

Query: 181 NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI 240
           NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI
Sbjct: 181 NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI 240

Query: 241 ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE 300
           ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE
Sbjct: 241 ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE 300

Query: 301 TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG 360
           TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG
Sbjct: 301 TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG 360

Query: 361 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY 420
           KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY
Sbjct: 361 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY 420

Query: 421 VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL 480
           VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL
Sbjct: 421 VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL 480

Query: 481 QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK 540
           QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK
Sbjct: 481 QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK 540

Query: 541 STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS 600
           STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS
Sbjct: 541 STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS 600

Query: 601 EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI 657
           EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI
Sbjct: 601 EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI 657


>gi|163310725 ER degradation enhancer, mannosidase alpha-like 3
           [Homo sapiens]
          Length = 932

 Score =  384 bits (986), Expect = e-106
 Identities = 208/454 (45%), Positives = 284/454 (62%), Gaps = 22/454 (4%)

Query: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196
           MF   Y NYM HA+P DEL P+ CRGR   + +PS  +++D LG +SLTL+D+LDTL ++
Sbjct: 59  MFDHAYGNYMEHAYPADELMPLTCRGRVRGQ-EPSRGDVDDALGKFSLTLIDSLDTLVVL 117

Query: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256
             + EF+ AV+ V+  V+ D D  V VFE  IRVLG LL  H +    K+    M  + Y
Sbjct: 118 NKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYM--QWY 175

Query: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV-PPD----TNNETCTAGAGSLLV 311
           ++ELL MA  L  +LLPAF NT +G+PYPR+NLK G+  P+    T  +TCTA AG+L++
Sbjct: 176 NDELLQMAKQLGYKLLPAF-NTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLIL 234

Query: 312 EFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDS 371
           EF  LSR  G + FE  AR+A+  LW  R   + L+G  +NI TG WV K SG+GAG+DS
Sbjct: 235 EFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDS 294

Query: 372 FYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQL- 430
           +YEYLLK+Y+L G+   LE FN  Y +I  Y+             PPL ++V++    L 
Sbjct: 295 YYEYLLKAYVLLGDDSFLERFNTHYDAIMRYI-----------SQPPLLLDVHIHKPMLN 343

Query: 431 MNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVLFYPL 490
             TW+D+L AFFPGLQVL GD+  AI  H   Y + K++  LPE +    +      +PL
Sbjct: 344 ARTWMDALLAFFPGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRV-HWAQHPL 402

Query: 491 RPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFF 550
           RPE  ESTY LY+AT +P+YL VG  ++++L KY +V CG+A +  V   S EDRM+SFF
Sbjct: 403 RPEFAESTYFLYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFF 462

Query: 551 LSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIV 584
           L+E  KYLYLLF +   +      Y+FTTE H++
Sbjct: 463 LAEMFKYLYLLFADKEDIIFDIEDYIFTTEAHLL 496


>gi|222537737 ER degradation enhancer, mannosidase alpha-like 2
           isoform 1 [Homo sapiens]
          Length = 578

 Score =  355 bits (911), Expect = 7e-98
 Identities = 214/525 (40%), Positives = 305/525 (58%), Gaps = 64/525 (12%)

Query: 128 AQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLV 187
           A  R+  + MF   YD+Y+ +AFP DEL P+ C G             +D  G++SLTL+
Sbjct: 33  AHYRERVKAMFYHAYDSYLENAFPFDELRPLTCDG-------------HDTWGSFSLTLI 79

Query: 188 DALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQP 247
           DALDTL I+GN SEFQ+ V+++ ++V FD D    VFE  IRV+G LLSAH +   SK+ 
Sbjct: 80  DALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLL---SKKA 136

Query: 248 FGDMTIK-DYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCTAGA 306
             ++         LL MA + A +LLPAF+ T TG+PY  VNL  GV P     TCTAG 
Sbjct: 137 GVEVEAGWPCSGPLLRMAEEAARKLLPAFQ-TPTGMPYGTVNLLHGVNPGETPVTCTAGI 195

Query: 307 GSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLG 366
           G+ +VEF  LS L GD  FE VAR A+  LW  RS D GL+GN +++ TG WV + +G+G
Sbjct: 196 GTFIVEFATLSSLTGDPVFEDVARVALMRLWESRS-DIGLVGNHIDVLTGKWVAQDAGIG 254

Query: 367 AGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMF 426
           AG+DS++EYL+K  IL  +K+ + MF    ++I+NY R               Y+ V M+
Sbjct: 255 AGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFD-----------DWYLWVQMY 303

Query: 427 SGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYN----WQLQA 482
            G +      SL+A++PGLQ LIGD+++A+     YY +WK++G LPE YN    + ++ 
Sbjct: 304 KGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEK 363

Query: 483 PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKST 542
            +   YPLRPEL+ES   LY+AT +P  L +G D ++S+EK +KV+CG+AT+  + D   
Sbjct: 364 REG--YPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKL 421

Query: 543 EDRMESFFLSETCKYLYLLFDEDNPVHKSGTR-----------------YMFTTEGHIVS 585
           ++RMESFFL+ET KYLYLLFD  N +H +G+                  Y+F TE H + 
Sbjct: 422 DNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPID 481

Query: 586 -----VDEHLRELPW------KEFFSEEGGQDQGGKSVHRPKPHE 619
                  + L+E  W      +EF+S +  + +  K+     P E
Sbjct: 482 PAALHCCQRLKEEQWEVEDLMREFYSLKRSRSKFQKNTVSSGPWE 526


>gi|222537739 ER degradation enhancer, mannosidase alpha-like 2
           isoform 2 [Homo sapiens]
          Length = 541

 Score =  328 bits (842), Expect = 7e-90
 Identities = 203/498 (40%), Positives = 288/498 (57%), Gaps = 56/498 (11%)

Query: 155 LNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVS 214
           L P H    GPD   P   + +     +SLTL+DALDTL I+GN SEFQ+ V+++ ++V 
Sbjct: 15  LLPQHHGAPGPDGSAPDPAHYS-----FSLTLIDALDTLLILGNVSEFQRVVEVLQDSVD 69

Query: 215 FDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIK-DYDNELLYMAHDLAVRLLP 273
           FD D    VFE  IRV+G LLSAH +   SK+   ++         LL MA + A +LLP
Sbjct: 70  FDIDVNASVFETNIRVVGGLLSAHLL---SKKAGVEVEAGWPCSGPLLRMAEEAARKLLP 126

Query: 274 AFENTKTGIPYPRVNLKTGVPPDTNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAV 333
           AF+ T TG+PY  VNL  GV P     TCTAG G+ +VEF  LS L GD  FE VAR A+
Sbjct: 127 AFQ-TPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVAL 185

Query: 334 KALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFN 393
             LW  RS D GL+GN +++ TG WV + +G+GAG+DS++EYL+K  IL  +K+ + MF 
Sbjct: 186 MRLWESRS-DIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 244

Query: 394 AAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVE 453
              ++I+NY R               Y+ V M+ G +      SL+A++PGLQ LIGD++
Sbjct: 245 EYNKAIRNYTRFD-----------DWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDID 293

Query: 454 DAICLHAFYYAIWKRYGALPERYN----WQLQAPDVLFYPLRPELVESTYLLYQATKNPF 509
           +A+     YY +WK++G LPE YN    + ++  +   YPLRPEL+ES   LY+AT +P 
Sbjct: 294 NAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREG--YPLRPELIESAMYLYRATGDPT 351

Query: 510 YLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVH 569
            L +G D ++S+EK +KV+CG+AT+  + D   ++RMESFFL+ET KYLYLLFD  N +H
Sbjct: 352 LLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIH 411

Query: 570 KSGTR-----------------YMFTTEGHIVS-----VDEHLRELPW------KEFFSE 601
            +G+                  Y+F TE H +        + L+E  W      +EF+S 
Sbjct: 412 NNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRLKEEQWEVEDLMREFYSL 471

Query: 602 EGGQDQGGKSVHRPKPHE 619
           +  + +  K+     P E
Sbjct: 472 KRSRSKFQKNTVSSGPWE 489


>gi|218749883 alpha 1,2-mannosidase [Homo sapiens]
          Length = 699

 Score =  188 bits (477), Expect = 2e-47
 Identities = 158/474 (33%), Positives = 230/474 (48%), Gaps = 66/474 (13%)

Query: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196
           +F+  +  Y   A+  DEL P+             + + ++  G   LTL+DALDT+ I+
Sbjct: 256 VFLHAWKGYRKFAWGHDELKPV-------------SRSFSEWFG-LGLTLIDALDTMWIL 301

Query: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256
           G   EF++A K V   + F+KD  V +FE+TIR+LG LLSA+ +  DS            
Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSL----------- 350

Query: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV--PPDTNNETCTAGAGSLLVEFG 314
               L  A D   RL+PAF  T + IPY  VN+ TGV  PP   +++  A   S+ +EF 
Sbjct: 351 ---FLRKAEDFGNRLMPAF-RTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFR 406

Query: 315 ILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG-KQSGLGAGLDSFY 373
            LSRL GD  F+    +  + +  L     GL+   +N  +G +       LGA  DS+Y
Sbjct: 407 ELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYY 466

Query: 374 EYLLKSYILFGEKED--LEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLM 431
           EYLLK +I  G++E   LE +  A + ++ +L R          +P     V   +    
Sbjct: 467 EYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLR--------HSEPSKLTFVGELAHGRF 518

Query: 432 NTWIDSLQAFFPGLQVL-------IGDVEDAICLHAFYYAIWKRY--GALPERYNWQLQA 482
           +  +D L  F PG   L          +E A  L    Y + ++   G  PE  ++ L  
Sbjct: 519 SAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYP 578

Query: 483 P----DVLFYP------LRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKC-GY 531
                DV   P      LRPE VES + LY+ T +  Y   G +ILQS  ++T+V   GY
Sbjct: 579 QPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGY 638

Query: 532 ATLHHVID---KSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGH 582
           +++++V D       D+MESFFL ET KYL+LLF +D P   S   Y+F TE H
Sbjct: 639 SSINNVQDPQKPEPRDKMESFFLGETLKYLFLLFSDD-PNLLSLDAYVFNTEAH 691


>gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens]
          Length = 641

 Score =  175 bits (444), Expect = 1e-43
 Identities = 154/503 (30%), Positives = 243/503 (48%), Gaps = 59/503 (11%)

Query: 103 VLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRG 162
           ++G RG  P++ + R           + R+  + M    +DNY  + +  +EL PI  +G
Sbjct: 164 LVGIRGGDPEDNDIR-----------EKREKIKEMMKHAWDNYRTYGWGHNELRPIARKG 212

Query: 163 RGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQ 222
             P+    S +           T+VDALDTL IMG   EF    + + + + F  +S V 
Sbjct: 213 HSPNIFGSSQMGA---------TIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVS 263

Query: 223 VFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGI 282
           VFE  IR +G LL+A+ +        G+   K         A  LA +LLPAF NT TGI
Sbjct: 264 VFEVNIRFIGGLLAAYYL-------SGEEIFK-------IKAVQLAEKLLPAF-NTPTGI 308

Query: 283 PYPRVNLKTGVPPD----TNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWN 338
           P+  VNLK+GV  +    +   +  A  G+L +EF  LS L GD T+ +     ++ L  
Sbjct: 309 PWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTY-YKKVMHIRKLLQ 367

Query: 339 LRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAA 395
                 GL  N +N +TG W    + +G   DSFYEYLLK++ L  +K D E   M++ A
Sbjct: 368 KMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAW-LMSDKTDHEARKMYDDA 426

Query: 396 YQSIQNYL----RRGREACNEGEGD--PPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLI 449
            ++I+ +L    R G     E +         ++  F+G +     D  +A   G  + +
Sbjct: 427 IEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLEL 486

Query: 450 GDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDV----LFYPLRPELVESTYLLYQAT 505
           G  E A   H  Y     + G    +++  ++A  V     +Y LRPE++E+ + L++ T
Sbjct: 487 G-AEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFT 545

Query: 506 KNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFD 563
            +P Y   G +   ++EKY +V  G++ +  V   +   +D  +SFFL+ET KYLYLLF 
Sbjct: 546 HDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFS 605

Query: 564 EDNPVHKSGTRYMFTTEGHIVSV 586
            D+ +      ++F TE H + V
Sbjct: 606 GDDLLPLD--HWVFNTEAHPLPV 626


>gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens]
          Length = 653

 Score =  164 bits (415), Expect = 2e-40
 Identities = 138/485 (28%), Positives = 235/485 (48%), Gaps = 65/485 (13%)

Query: 129 QMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVD 188
           + R   + M    ++NY  +A+  +EL PI        +G  S+    ++ G    T+VD
Sbjct: 194 EKRAKIKEMMKHAWNNYKGYAWGLNELKPI-------SKGGHSSSLFGNIKG---ATIVD 243

Query: 189 ALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPF 248
           ALDTL IM    EF++A   V   + F+ ++ + VFE  IR +G LLSA+ +    ++ F
Sbjct: 244 ALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYL--SGEEIF 301

Query: 249 GDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV----PPDTNNETCTA 304
               +            +L V+LLPAF +T +GIP+  +N+K+G+    P  +   +  A
Sbjct: 302 RKKAV------------ELGVKLLPAF-HTPSGIPWALLNMKSGIGRNWPWASGGSSILA 348

Query: 305 GAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSG 364
             G+L +EF  LS L G+  F       ++ + N      GL  N +N  +G W      
Sbjct: 349 EFGTLHLEFMHLSHLSGNPIFAEKVMN-IRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVS 407

Query: 365 LGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEGEGDPPLYV 421
           +G   DSFYEYLLK++ L  +K DLE   M+  A Q+I+ +L R   +            
Sbjct: 408 VGGLGDSFYEYLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSG---------LT 457

Query: 422 NVNMFSGQLMNTWIDSLQAFFPGLQVLIGD--------------VEDAICLHAFYYAIWK 467
            +  + G L+   +  L  F  G+  L  D               E A   H  Y   + 
Sbjct: 458 YIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFM 517

Query: 468 RYGALPERYNWQLQA----PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEK 523
           + G    R++  ++A     +  +Y LRPE++E+   +++ T +P Y     + +++LE 
Sbjct: 518 KLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALEN 577

Query: 524 YTKVKCGYATLH--HVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEG 581
           + +V  GY+ L   +++ +S +D  +SFFL+ET KYLYL+F +D+ +      ++F +E 
Sbjct: 578 HCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLE--HWIFNSEA 635

Query: 582 HIVSV 586
           H++ +
Sbjct: 636 HLLPI 640


>gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens]
          Length = 630

 Score =  157 bits (398), Expect = 2e-38
 Identities = 150/499 (30%), Positives = 232/499 (46%), Gaps = 86/499 (17%)

Query: 125 QLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYS- 183
           Q+RAQ R+  + M  F + +Y  +A  ++EL P+   G              ++ G  S 
Sbjct: 170 QVRAQ-REKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYE-----------GNMFGGLSG 217

Query: 184 LTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITD 243
            T++D+LDTL +M    EFQ+A   V  +   +      +FE  IR +G LLSA  +   
Sbjct: 218 ATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYL--T 275

Query: 244 SKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCT 303
            ++ F    I+            L  +LLPAF NT TGIP   V+ K+G     N    T
Sbjct: 276 GEEVFRIKAIR------------LGEKLLPAF-NTPTGIPKGVVSFKSG-----NWGWAT 317

Query: 304 AGAGSLLVEFGI-------LSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTG 356
           AG+ S+L EFG        L+ L G+  F    R   K L  +     GL  N ++  +G
Sbjct: 318 AGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI-EKPFGLYPNFLSPVSG 376

Query: 357 HWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEG 413
           +WV     +G   DSFYEYL+KS+++ G K D+E   M+  A ++I+ YL          
Sbjct: 377 NWVQHHVSVGGLGDSFYEYLIKSWLMSG-KTDMEAKNMYYEALEAIETYLL--------- 426

Query: 414 EGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDA----------------IC 457
              P     +  + G +++  +  L  F  G+  L    EDA                  
Sbjct: 427 NVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIAL--GAEDAKEEKRAHYRELAAQITKT 484

Query: 458 LHAFYYAIWKRYGALPERYNWQLQAPDVL-------FYPLRPELVESTYLLYQATKNPFY 510
            H  Y     + G  PE + W     + +       +Y LRPE+VES   L++ T NP Y
Sbjct: 485 CHESYARSDTKLG--PEAF-WFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIY 541

Query: 511 LHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFDEDNPV 568
              G +++ +LEKY + + G++ +  V   +   +++ +SFFL+ET KYLYLLF ED+ +
Sbjct: 542 REWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLL 601

Query: 569 HKSGTRYMFTTEGHIVSVD 587
             S   ++F TE H + V+
Sbjct: 602 --SLEDWVFNTEAHPLPVN 618


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 30/73 (41%), Positives = 32/73 (43%), Gaps = 8/73 (10%)

Query: 49  PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKA-PRRPGPGMCGPANWGYVLGGR 107
           P GP  P  GP G PGG  GP  L PP       PR   P   GPG   P   G + GG 
Sbjct: 644 PPGPGGPMPGPHGGPGGPVGPRLLGPP-----PPPRGGDPFWDGPG--DPMRGGPMRGGP 696

Query: 108 GRGPDEYEKRYSG 120
           G GP  Y +   G
Sbjct: 697 GPGPGPYHRGRGG 709


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
            sapiens]
          Length = 1487

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%)

Query: 47   RSPDGPASPTS--------GPVGRPG-----GVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93
            R P GP  P+         GP+G PG     G +GP+   PPG      P   P  PGPG
Sbjct: 1163 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG--PPGNPGPPGP---PGPPGPG 1217

Query: 94   MCGPANWGYVLGGRGRGPD 112
            +   A  G  LG R +GPD
Sbjct: 1218 IDMSAFAG--LGPREKGPD 1234



 Score = 36.2 bits (82), Expect = 0.098
 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 18/99 (18%)

Query: 47   RSPDGPASPT--SGPVGRPGGVSGPSWLQPPGTGAAQSPR---------KAPRRPG-PGM 94
            R P GP  P   +GP G PG    P    PPG   A   +          AP  PG PG 
Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075

Query: 95   CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDL 133
             GPA      G  G+  D  E    G   P   A  R +
Sbjct: 1076 PGPA------GPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 15/136 (11%)

Query: 47   RSPDGPASPT-----SGPVGRPGGVSGPSWLQPPGTGAAQSPRKA------PRRPG-PGM 94
            R   GP   T     +G VG PG    P    PPG      P+ A      P R G PG+
Sbjct: 887  RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946

Query: 95   CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDE 154
             GPA      G +G   D+      G   PQ  A  R +       G   +     P  E
Sbjct: 947  QGPAG---PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 1003

Query: 155  LNPIHCRGRGPDRGDP 170
                   G   DRG P
Sbjct: 1004 PGKQGAPGASGDRGPP 1019



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 41/147 (27%), Positives = 51/147 (34%), Gaps = 23/147 (15%)

Query: 49  PDGPASPTSGP--VGRPG--------GVSGPSWLQ----PPGTGAAQSPRKAPRRPG--- 91
           P GP  P  GP   G PG        G  GP   Q     PGT  +  P  A   PG   
Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 414

Query: 92  -PGMCGPANWGYVLGGRG----RGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYM 146
            PG  G A    + G  G    RGP    +  +G   P+ +     +A      G     
Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473

Query: 147 AHAFPQDELNPIHCRGRGPDRGDPSNL 173
             A PQ    P    G+   RG+P  +
Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGV 500



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 46  LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG-PGMCGPAN 99
           ++ P GP  P    GP G PG  G  G P     PG      PR  P  PG PG  G A 
Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258

Query: 100 WGYVLGGRG 108
                G RG
Sbjct: 259 KPGKAGERG 267



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 57  SGPVGRPG--GVSGPSW-LQPPGTGAAQSPRKAPRR------PGP-GMCGPANWGYVLGG 106
           +GP+G PG  G +G    + PPG   +   R AP        PGP G  GP       G 
Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 847

Query: 107 RGRGPDEYEKRYSGAFPPQ 125
           +G   +  +K  +GA  PQ
Sbjct: 848 KGEQGEAGQKGDAGAPGPQ 866



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 27/82 (32%), Positives = 28/82 (34%), Gaps = 18/82 (21%)

Query: 35  QRFPLSFGFQRLRSPDGPASPTSGP--VGRPGGVSGPSWLQP------------PGTGAA 80
           Q  P   GFQ L  P GP      P   G PG    P  + P            PG    
Sbjct: 656 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715

Query: 81  QSPRKAPRRPG----PGMCGPA 98
           Q PR  P  PG     G  GPA
Sbjct: 716 QGPRGLPGTPGTDGPKGASGPA 737



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 14/63 (22%)

Query: 47  RSPDGPASPTSGPVGRPGGVSGPSWLQPPG-------TGA-----AQSPRKAPRRPG-PG 93
           R  DG   P +GP G  G   GP +   PG       TGA     AQ PR  P  PG PG
Sbjct: 344 RGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 402

Query: 94  MCG 96
             G
Sbjct: 403 PAG 405



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)

Query: 58  GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGP 97
           GP+G PG    P     PG      P+ AP   GP G+ GP
Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 9/76 (11%)

Query: 42  GFQRLRSPDG-PASP-TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP------- 92
           G Q L+ P G P +P T GP G  G    P    PPG       R A    GP       
Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770

Query: 93  GMCGPANWGYVLGGRG 108
           G  GP       GGRG
Sbjct: 771 GEKGPEGAPGKDGGRG 786


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
            sapiens]
          Length = 1418

 Score = 38.9 bits (89), Expect = 0.015
 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%)

Query: 47   RSPDGPASPTS--------GPVGRPG-----GVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93
            R P GP  P+         GP+G PG     G +GP+   PPG      P   P  PGPG
Sbjct: 1094 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG--PPGNPGPPGP---PGPPGPG 1148

Query: 94   MCGPANWGYVLGGRGRGPD 112
            +   A  G  LG R +GPD
Sbjct: 1149 IDMSAFAG--LGPREKGPD 1165



 Score = 36.2 bits (82), Expect = 0.098
 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 18/99 (18%)

Query: 47   RSPDGPASPT--SGPVGRPGGVSGPSWLQPPGTGAAQSPR---------KAPRRPG-PGM 94
            R P GP  P   +GP G PG    P    PPG   A   +          AP  PG PG 
Sbjct: 947  RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006

Query: 95   CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDL 133
             GPA      G  G+  D  E    G   P   A  R +
Sbjct: 1007 PGPA------GPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 15/136 (11%)

Query: 47  RSPDGPASPT-----SGPVGRPGGVSGPSWLQPPGTGAAQSPRKA------PRRPG-PGM 94
           R   GP   T     +G VG PG    P    PPG      P+ A      P R G PG+
Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877

Query: 95  CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDE 154
            GPA      G +G   D+      G   PQ  A  R +       G   +     P  E
Sbjct: 878 QGPAG---PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 934

Query: 155 LNPIHCRGRGPDRGDP 170
                  G   DRG P
Sbjct: 935 PGKQGAPGASGDRGPP 950



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 41/147 (27%), Positives = 51/147 (34%), Gaps = 23/147 (15%)

Query: 49  PDGPASPTSGP--VGRPG--------GVSGPSWLQ----PPGTGAAQSPRKAPRRPG--- 91
           P GP  P  GP   G PG        G  GP   Q     PGT  +  P  A   PG   
Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 345

Query: 92  -PGMCGPANWGYVLGGRG----RGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYM 146
            PG  G A    + G  G    RGP    +  +G   P+ +     +A      G     
Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404

Query: 147 AHAFPQDELNPIHCRGRGPDRGDPSNL 173
             A PQ    P    G+   RG+P  +
Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGV 431



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 6/69 (8%)

Query: 46  LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG-PGMCGPAN 99
           ++ P GP  P    GP G PG  G  G P     PG      PR  P  PG PG  G A 
Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189

Query: 100 WGYVLGGRG 108
                G RG
Sbjct: 190 KPGKAGERG 198



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 10/79 (12%)

Query: 57  SGPVGRPG--GVSGPSW-LQPPGTGAAQSPRKAPRR------PGP-GMCGPANWGYVLGG 106
           +GP+G PG  G +G    + PPG   +   R AP        PGP G  GP       G 
Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778

Query: 107 RGRGPDEYEKRYSGAFPPQ 125
           +G   +  +K  +GA  PQ
Sbjct: 779 KGEQGEAGQKGDAGAPGPQ 797



 Score = 32.0 bits (71), Expect = 1.9
 Identities = 27/82 (32%), Positives = 28/82 (34%), Gaps = 18/82 (21%)

Query: 35  QRFPLSFGFQRLRSPDGPASPTSGP--VGRPGGVSGPSWLQP------------PGTGAA 80
           Q  P   GFQ L  P GP      P   G PG    P  + P            PG    
Sbjct: 587 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646

Query: 81  QSPRKAPRRPG----PGMCGPA 98
           Q PR  P  PG     G  GPA
Sbjct: 647 QGPRGLPGTPGTDGPKGASGPA 668



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 14/63 (22%)

Query: 47  RSPDGPASPTSGPVGRPGGVSGPSWLQPPG-------TGA-----AQSPRKAPRRPG-PG 93
           R  DG   P +GP G  G   GP +   PG       TGA     AQ PR  P  PG PG
Sbjct: 275 RGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 333

Query: 94  MCG 96
             G
Sbjct: 334 PAG 336



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%)

Query: 58  GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGP 97
           GP+G PG    P     PG      P+ AP   GP G+ GP
Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 9/76 (11%)

Query: 42  GFQRLRSPDG-PASP-TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP------- 92
           G Q L+ P G P +P T GP G  G    P    PPG       R A    GP       
Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701

Query: 93  GMCGPANWGYVLGGRG 108
           G  GP       GGRG
Sbjct: 702 GEKGPEGAPGKDGGRG 717


>gi|119508426 alpha 3 type IX collagen [Homo sapiens]
          Length = 684

 Score = 38.1 bits (87), Expect = 0.026
 Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 8/74 (10%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPG--GVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPA 98
           G QR+  P  P  P  GP G+PG  G+ G +   PPG      P+ AP +PG PG  G  
Sbjct: 24  GAQRVGLPGPPGPP--GPPGKPGQDGIDGEAG--PPGLPGPPGPKGAPGKPGKPGEAGLP 79

Query: 99  NWGYVLGGRGR-GP 111
               V G  GR GP
Sbjct: 80  GLPGVDGLTGRDGP 93


>gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens]
          Length = 1388

 Score = 37.0 bits (84), Expect = 0.058
 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%)

Query: 44  QRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG----PGMCGPAN 99
           Q LR P GP  P   P G PG      ++ PPG+     P   P  PG    PG+ G   
Sbjct: 615 QLLRGPPGPPGPPGLP-GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG 673

Query: 100 WGYVLGGRG-RGPD 112
              + G +G RGP+
Sbjct: 674 LPGMKGEKGARGPN 687


>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
           sapiens]
          Length = 647

 Score = 37.0 bits (84), Expect = 0.058
 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 8/66 (12%)

Query: 49  PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLG--- 105
           P G      GP   PGG   P   +P  TG  Q P   PR P     GPA+ G+  G   
Sbjct: 406 PSGAGPAREGPAAWPGGAPTPPHARP--TGRRQDPEPGPRAP---RGGPASSGWHAGSAA 460

Query: 106 GRGRGP 111
           GRG  P
Sbjct: 461 GRGWDP 466


>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
           sapiens]
          Length = 647

 Score = 37.0 bits (84), Expect = 0.058
 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 8/66 (12%)

Query: 49  PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLG--- 105
           P G      GP   PGG   P   +P  TG  Q P   PR P     GPA+ G+  G   
Sbjct: 406 PSGAGPAREGPAAWPGGAPTPPHARP--TGRRQDPEPGPRAP---RGGPASSGWHAGSAA 460

Query: 106 GRGRGP 111
           GRG  P
Sbjct: 461 GRGWDP 466


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 11/58 (18%)

Query: 47   RSPDGPASPTSGPVGRPG--GVSGPSWLQ-PPGTGAAQSPRKAPRRPGP----GMCGP 97
            R P GPA    GP GR G  G  G + L+ PPG      P+ AP +PGP    G+ GP
Sbjct: 1392 RGPPGPA----GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445



 Score = 36.2 bits (82), Expect = 0.098
 Identities = 42/141 (29%), Positives = 51/141 (36%), Gaps = 18/141 (12%)

Query: 42  GFQRLRSPDGPASPTS--GPVGRPGGVSGPSWLQPPGTGAAQSP---RKAPRRPGP---- 92
           G Q L  P G   P    GP+G+PG    P    PPG    + P   +     PGP    
Sbjct: 727 GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI 786

Query: 93  GMCGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQ 152
           G  GP       G RG    + EK   G FP             M + G    +    P+
Sbjct: 787 GYPGPRGVKGADGIRGLKGTKGEKGEDG-FP--------GFKGDMGIKGDRGEIGPPGPR 837

Query: 153 DELNPIHCRGRGPDRGDPSNL 173
            E  P   +GRG   GDP  L
Sbjct: 838 GEDGPEGPKGRGGPNGDPGPL 858



 Score = 31.2 bits (69), Expect = 3.2
 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 10/77 (12%)

Query: 42   GFQRLRSPDGPASP-----TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMC 95
            GF   R   GP          GP G PG    P    P G   A  P   P RPGP G  
Sbjct: 1057 GFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG---AAGPIGIPGRPGPQGPP 1113

Query: 96   GPANWGYVLGGRG-RGP 111
            GPA      G +G +GP
Sbjct: 1114 GPAGEKGAPGEKGPQGP 1130



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 18/70 (25%)

Query: 46  LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG--------- 91
           LR P GP   T   GPVG PG  G+ G P  + P G    Q P     +PG         
Sbjct: 557 LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDG 616

Query: 92  ----PGMCGP 97
               PG  GP
Sbjct: 617 ARGMPGQTGP 626



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 16/81 (19%)

Query: 49   PDGPASPTS-----GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYV 103
            P GP  P+      GP G PGG+  P        G    P +A     PG  GP      
Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPG-----AVGEKGEPGEAGEPGLPGEGGPP----- 1302

Query: 104  LGGRGRGPDEYEKRYSGAFPP 124
             G +G   ++ E   SGA  P
Sbjct: 1303 -GPKGERGEKGESGPSGAAGP 1322


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score = 36.6 bits (83), Expect = 0.075
 Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 10/69 (14%)

Query: 47   RSPDGPASPTS--GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPANWGYV 103
            R P GPA      G  GRPG   GP    PPG    Q  +  P RPG P + GPA    V
Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGA-KGPEG--PPGPTGRQGEKGEPGRPGDPAVVGPA----V 1549

Query: 104  LGGRGRGPD 112
             G +G   D
Sbjct: 1550 AGPKGEKGD 1558



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 29/77 (37%), Positives = 32/77 (41%), Gaps = 8/77 (10%)

Query: 42   GFQRLRSPDGPASPTS-GPVGRPGGVSGPSWLQ----PPGTGAAQSPRKAPRRPG-PGMC 95
            G Q  R P G   P   GP G PG   GP  L     PPG       +  P RPG PG  
Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGD-RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV 1627

Query: 96   GPANWGYVLGGRG-RGP 111
            GP      +G +G  GP
Sbjct: 1628 GPRGRDGEVGEKGDEGP 1644


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 30/85 (35%), Positives = 33/85 (38%), Gaps = 18/85 (21%)

Query: 42  GFQRLRSPDGPASP--------TSGPVGRPG--------GVSGPSWLQ-PPGTGAAQSPR 84
           GF   R P GP  P         SG  G PG        G  GP  +Q PPG    +  R
Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469

Query: 85  KAPRRPGP-GMCGPANWGYVLGGRG 108
            A   PGP G+ GP       G RG
Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRG 494



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 5/54 (9%)

Query: 49  PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP----GMCGPA 98
           P GP  P +GP G PG V       P G   ++ P+     PGP    G  GPA
Sbjct: 333 PPGPTGP-AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPA 385



 Score = 34.7 bits (78), Expect = 0.29
 Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 8/75 (10%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG----PGMCGP 97
           GFQ L  P GP     G  G+PG    P  L  PG   A+  R  P   G    PG  GP
Sbjct: 641 GFQGLPGPAGPP----GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696

Query: 98  ANWGYVLGGRGRGPD 112
                  G  G   D
Sbjct: 697 RGANGAPGNDGAKGD 711



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 28/78 (35%), Positives = 32/78 (41%), Gaps = 12/78 (15%)

Query: 57  SGPVGRPG--------GVSGPSW-LQPPGTGAAQSPRKAPRRPGP-GMCGPANWGYVLGG 106
           +GP+G PG        G SGPS    P G   A   R  P  PGP G  GP       G 
Sbjct: 766 TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825

Query: 107 RGRGPDEYEKRYSGAFPP 124
           +G   D   K  +G  PP
Sbjct: 826 KGEPGDAGAKGDAG--PP 841



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 15/75 (20%)

Query: 49  PDGPASPTS-----GPVGRPGGVSGPSWLQPP---------GTGAAQSPRKAPRRPGP-G 93
           P GP  P       GP G  G    P  + PP         G+  A  P  AP  PGP G
Sbjct: 894 PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG 953

Query: 94  MCGPANWGYVLGGRG 108
           + G      + G RG
Sbjct: 954 IAGQRGVVGLPGQRG 968



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 11/74 (14%)

Query: 47  RSPDGPASPTS-----GPVGRPG--GVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPA 98
           + P GPA P       GP G PG  G+ GP+   PPG       +  P   G PG  G  
Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPA--GPPGEAGKPGEQGVPGDLGAPGPSGAR 676

Query: 99  NWGYVLGGRG-RGP 111
                 G RG +GP
Sbjct: 677 GERGFPGERGVQGP 690


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 36.2 bits (82), Expect = 0.098
 Identities = 24/69 (34%), Positives = 26/69 (37%), Gaps = 2/69 (2%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPANW 100
           G+     P GP  P  G  G PG    P +  PPG      P   P  PG  G  GPA  
Sbjct: 171 GYPGPAGPPGPPGPP-GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229

Query: 101 GYVLGGRGR 109
               G  GR
Sbjct: 230 DGESGRPGR 238



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 27/63 (42%), Positives = 28/63 (44%), Gaps = 6/63 (9%)

Query: 49  PDGPASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRPGPGMCGPANWGYVLG 105
           P GP  PT GP G  G  G  GP  LQ  PGTG        P  PGP   G A      G
Sbjct: 616 PQGPPGPT-GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK--GDAGAPGAPG 672

Query: 106 GRG 108
           G+G
Sbjct: 673 GKG 675



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 2/50 (4%)

Query: 49   PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97
            P GP  P SGP G+ G    P  + PPG    +  R +   PG PG  GP
Sbjct: 1138 PRGPVGP-SGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186



 Score = 30.4 bits (67), Expect = 5.4
 Identities = 19/56 (33%), Positives = 21/56 (37%), Gaps = 4/56 (7%)

Query: 38  PLSFGFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93
           P   GF   +  DG      G  G  GG  GP    PPG      P+  P   GPG
Sbjct: 575 PGVMGFPGPKGNDG----APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%)

Query: 51  GPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGP 97
           GP  P SGP G+PG +  P    P G   A  P K   R GPG  GP
Sbjct: 564 GPPGP-SGPRGQPGVMGFPG---PKGNDGA--PGKNGERGGPGGPGP 604



 Score = 29.6 bits (65), Expect = 9.2
 Identities = 19/60 (31%), Positives = 22/60 (36%), Gaps = 5/60 (8%)

Query: 50  DGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPANWGYVLGGRG 108
           DGP     GP G  G    P    P G       + +P   G PG  GP     + G RG
Sbjct: 902 DGPP----GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG 957



 Score = 29.6 bits (65), Expect = 9.2
 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 3/51 (5%)

Query: 48   SPDGPASPTSGPVGRPGGVSGPSWLQPPG-TGAAQSPRKAPRRPGPGMCGP 97
            +P  P SP  GP G+ G +  P    P G  G +  P K      PG  GP
Sbjct: 1114 NPGAPGSP--GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP 1162


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 5/64 (7%)

Query: 49   PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAA---QSPRKAPRRPG-PGMCGPANWGYVL 104
            P GPA P SGP G+ G    P  + P G       Q P   P  PG PG  G +  GY  
Sbjct: 1052 PRGPAGP-SGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDF 1110

Query: 105  GGRG 108
            G  G
Sbjct: 1111 GYDG 1114



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 24/69 (34%), Positives = 25/69 (36%), Gaps = 9/69 (13%)

Query: 49  PDGPASPT--------SGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPAN 99
           P GPA P         SGPVG PG           G         AP  PGP G+ GP  
Sbjct: 275 PAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVG 334

Query: 100 WGYVLGGRG 108
                G RG
Sbjct: 335 AAGATGARG 343



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 41/130 (31%), Positives = 49/130 (37%), Gaps = 41/130 (31%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPG--------GVSGPSWLQ----PPGTGAAQSP------ 83
           GFQ L  P GPA    G VG+PG        G+ GP+  +    PPG   A  P      
Sbjct: 553 GFQGLPGPSGPA----GEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGS 608

Query: 84  RKAPRRPGP-------------GMCGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQM 130
           R     PGP             G  GP+    + G RG       K   G   P LR ++
Sbjct: 609 RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKG--EPGLRGEI 666

Query: 131 ----RDLARG 136
               RD ARG
Sbjct: 667 GNPGRDGARG 676


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein
           [Homo sapiens]
          Length = 1650

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%)

Query: 49  PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106
           P+GPA     P   G PG V  P    PPG         AP  PG  +  P  +G   GG
Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 374

Query: 107 RGRGP 111
             +GP
Sbjct: 375 GDKGP 379



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%)

Query: 49   PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99
            P GP  PT   GP G PG V  P    PPG G       A+  R     PG PG  GP  
Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1223

Query: 100  WGYVLGGRG-RGP 111
                 G  G RGP
Sbjct: 1224 ENGPPGPLGKRGP 1236



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%)

Query: 42  GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90
           GFQ    P GP        A+  +GP+G  G  G  GP   Q  PGT   +  +  P  P
Sbjct: 827 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886

Query: 91  G-PGMCGPANWGYVLGGRG 108
           G PG  GPA      G RG
Sbjct: 887 GAPGKDGPAGLRGFPGERG 905



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%)

Query: 42  GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98
           G Q L  P G   P    GP G+PG    P    PPG    + P       GP G  GP 
Sbjct: 569 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 628

Query: 99  NWGYVLGGRG 108
            +    G +G
Sbjct: 629 GYPGPRGVKG 638



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97
           G +    P GP  P   P G  G       + PPG    Q P  A    G PG  GP
Sbjct: 914 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein
           [Homo sapiens]
          Length = 1629

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%)

Query: 49  PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106
           P+GPA     P   G PG V  P    PPG         AP  PG  +  P  +G   GG
Sbjct: 296 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 353

Query: 107 RGRGP 111
             +GP
Sbjct: 354 GDKGP 358



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%)

Query: 49   PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99
            P GP  PT   GP G PG V  P    PPG G       A+  R     PG PG  GP  
Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1202

Query: 100  WGYVLGGRG-RGP 111
                 G  G RGP
Sbjct: 1203 ENGPPGPLGKRGP 1215



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%)

Query: 42  GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90
           GFQ    P GP        A+  +GP+G  G  G  GP   Q  PGT   +  +  P  P
Sbjct: 806 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865

Query: 91  G-PGMCGPANWGYVLGGRG 108
           G PG  GPA      G RG
Sbjct: 866 GAPGKDGPAGLRGFPGERG 884



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%)

Query: 42  GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98
           G Q L  P G   P    GP G+PG    P    PPG    + P       GP G  GP 
Sbjct: 548 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 607

Query: 99  NWGYVLGGRG 108
            +    G +G
Sbjct: 608 GYPGPRGVKG 617



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97
           G +    P GP  P   P G  G       + PPG    Q P  A    G PG  GP
Sbjct: 893 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein
           [Homo sapiens]
          Length = 1736

 Score = 35.8 bits (81), Expect = 0.13
 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%)

Query: 49  PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106
           P+GPA     P   G PG V  P    PPG         AP  PG  +  P  +G   GG
Sbjct: 403 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 460

Query: 107 RGRGP 111
             +GP
Sbjct: 461 GDKGP 465



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%)

Query: 49   PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99
            P GP  PT   GP G PG V  P    PPG G       A+  R     PG PG  GP  
Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1309

Query: 100  WGYVLGGRG-RGP 111
                 G  G RGP
Sbjct: 1310 ENGPPGPLGKRGP 1322



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%)

Query: 42  GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90
           GFQ    P GP        A+  +GP+G  G  G  GP   Q  PGT   +  +  P  P
Sbjct: 913 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972

Query: 91  G-PGMCGPANWGYVLGGRG 108
           G PG  GPA      G RG
Sbjct: 973 GAPGKDGPAGLRGFPGERG 991



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%)

Query: 42  GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98
           G Q L  P G   P    GP G+PG    P    PPG    + P       GP G  GP 
Sbjct: 655 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 714

Query: 99  NWGYVLGGRG 108
            +    G +G
Sbjct: 715 GYPGPRGVKG 724



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%)

Query: 42   GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97
            G +    P GP  P   P G  G       + PPG    Q P  A    G PG  GP
Sbjct: 1000 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 1055


>gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens]
          Length = 703

 Score = 35.0 bits (79), Expect = 0.22
 Identities = 37/108 (34%), Positives = 41/108 (37%), Gaps = 8/108 (7%)

Query: 51  GPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKA-----PRRPG-PGMCGPANWGYVL 104
           GPA P  GP G PG    P    PPG G A  P  A     P  PG PG+ GP       
Sbjct: 469 GPAGPI-GPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPP 527

Query: 105 GGRGRGPDEYEKRYSGAFPPQLRAQMRDLAR-GMFVFGYDNYMAHAFP 151
           G  G      E   +G   P    +   L + G   FG     AHA P
Sbjct: 528 GPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP 575



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 12/80 (15%)

Query: 42  GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPANW 100
           G   L  P GP    SG  G PG    P  + P G G        P  PGP G  GPA  
Sbjct: 284 GAAGLPGPQGP----SGAKGEPGTRGPPGLIGPTGYG-------MPGLPGPKGDRGPAGV 332

Query: 101 GYVLGGRGRGPDEYEKRYSG 120
             +LG RG   ++ E    G
Sbjct: 333 PGLLGDRGEPGEDGEPGEQG 352



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 1/61 (1%)

Query: 49  PDGPASPTSGPVGRPGGVSGPSWLQPPG-TGAAQSPRKAPRRPGPGMCGPANWGYVLGGR 107
           P  P +P  G    P G+ GP+ L  PG  G   +P        PG+ GP      +G +
Sbjct: 213 PGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPK 272

Query: 108 G 108
           G
Sbjct: 273 G 273


>gi|33286446 opioid growth factor receptor [Homo sapiens]
          Length = 677

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 3/49 (6%)

Query: 50  DGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98
           +G   P  G  G P    GPS   P G   A+SP +    PGP   GPA
Sbjct: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSET---PGPRPAGPA 550



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 5/51 (9%)

Query: 48  SPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98
           SP GPA     P   P    GP    P G   A+SP +    PGP   GPA
Sbjct: 525 SPAGPAGDE--PAESPSETPGPRPAGPAGDEPAESPSET---PGPRPAGPA 570



 Score = 30.0 bits (66), Expect = 7.1
 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 4/48 (8%)

Query: 52  PASPTSG-PVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98
           PA PT   P   P    GP    P G   A+SP +    PGP   GPA
Sbjct: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET---PGPRPAGPA 630


>gi|118498339 EMI domain containing 2 [Homo sapiens]
          Length = 439

 Score = 34.7 bits (78), Expect = 0.29
 Identities = 33/104 (31%), Positives = 37/104 (35%), Gaps = 25/104 (24%)

Query: 38  PLSFGFQRLRSPDGPASPTS-----GPVGRPG-----------GVSGP-SWLQPPGTGAA 80
           PL+    R R P GPA P       GP G PG           G +GP   L PPG    
Sbjct: 184 PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243

Query: 81  QSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSGAFPP 124
                 P  PGP   GPA      G  G  P+  +       PP
Sbjct: 244 PGEMGRPGPPGPP--GPA------GNPGPSPNSPQGALYSLQPP 279


>gi|239754674 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 480

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 9/79 (11%)

Query: 40  SFGFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPG--TGAAQSPR------KAPRRPG 91
           SFG +    P  P   T+ P  +PG  + P+ ++ PG   GA++ PR      + P  PG
Sbjct: 189 SFGGRPKSQPPLPQE-TAAPAPQPGPTAPPARVREPGRAEGASREPRLRSRAARPPPAPG 247

Query: 92  PGMCGPANWGYVLGGRGRG 110
           PG    A+     G  G G
Sbjct: 248 PGALSRASRSRAAGRPGPG 266


>gi|18105032 type X collagen alpha 1 precursor [Homo sapiens]
          Length = 680

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 28/67 (41%), Positives = 30/67 (44%), Gaps = 12/67 (17%)

Query: 42  GFQRLRSPDGPASPT-----SGPVGRPG----GVSG-PSWLQPPGTGAAQSPRKAPRRPG 91
           G Q    P GPA P      SGP G+PG    G+ G P    PPG  A   P   P  PG
Sbjct: 57  GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKP-GVPGLPG 115

Query: 92  -PGMCGP 97
            PG  GP
Sbjct: 116 KPGERGP 122



 Score = 32.7 bits (73), Expect = 1.1
 Identities = 36/111 (32%), Positives = 39/111 (35%), Gaps = 20/111 (18%)

Query: 16  GLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPVGRPG--------GVS 67
           GL G   L    GPS       P   G    R P GP     GP G PG        G+ 
Sbjct: 89  GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV-GPAGLPGPRGPPGPPGIP 147

Query: 68  GPSWLQPPGTGAAQSPRKAPRRPG----------PGMCG-PANWGYVLGGR 107
           GP+ +  PG    Q P  AP   G          PGM G     GY   GR
Sbjct: 148 GPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGR 198



 Score = 32.3 bits (72), Expect = 1.4
 Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 19/82 (23%)

Query: 58  GPVGRPG-----GVSGPSWLQ-------PPGTGAAQSPRKAPRR---PGP----GMCGPA 98
           GP G PG     G  GP+ L        PPG    Q P+  P     PGP    G  GPA
Sbjct: 311 GPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPA 370

Query: 99  NWGYVLGGRGRGPDEYEKRYSG 120
            +    G RG    + +  Y G
Sbjct: 371 GYPGAKGERGSPGSDGKPGYPG 392


>gi|38373671 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 33/95 (34%), Positives = 37/95 (38%), Gaps = 17/95 (17%)

Query: 38  PLSFGFQRLRSPDGPASPTS---GP-VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93
           P + G  RL S  GP  P     GP V +P  VS P    PPGT         P  P P 
Sbjct: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT-----QMTGPLGPLPP 269

Query: 94  MCGPANWGYV-----LGGRGRGPDEYEKRYSGAFP 123
           M  P   GY        G  RGP   +  Y G +P
Sbjct: 270 MHSPQQPGYQPQQNGSFGPARGP---QSNYGGPYP 301


>gi|38373669 SEC24-related protein C [Homo sapiens]
          Length = 1094

 Score = 34.3 bits (77), Expect = 0.37
 Identities = 33/95 (34%), Positives = 37/95 (38%), Gaps = 17/95 (17%)

Query: 38  PLSFGFQRLRSPDGPASPTS---GP-VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93
           P + G  RL S  GP  P     GP V +P  VS P    PPGT         P  P P 
Sbjct: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT-----QMTGPLGPLPP 269

Query: 94  MCGPANWGYV-----LGGRGRGPDEYEKRYSGAFP 123
           M  P   GY        G  RGP   +  Y G +P
Sbjct: 270 MHSPQQPGYQPQQNGSFGPARGP---QSNYGGPYP 301


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.140    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,537,105
Number of Sequences: 37866
Number of extensions: 1557457
Number of successful extensions: 6867
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 207
Number of HSP's that attempted gapping in prelim test: 5922
Number of HSP's gapped (non-prelim): 1053
length of query: 657
length of database: 18,247,518
effective HSP length: 109
effective length of query: 548
effective length of database: 14,120,124
effective search space: 7737827952
effective search space used: 7737827952
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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