BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo sapiens] (657 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Ho... 1358 0.0 gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [... 384 e-106 gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 i... 355 7e-98 gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 i... 328 7e-90 gi|218749883 alpha 1,2-mannosidase [Homo sapiens] 188 2e-47 gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens] 175 1e-43 gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens] 164 2e-40 gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens] 157 2e-38 gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s... 45 2e-04 gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom... 39 0.015 gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom... 39 0.015 gi|119508426 alpha 3 type IX collagen [Homo sapiens] 38 0.026 gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] 37 0.058 gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ... 37 0.058 gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ... 37 0.058 gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] 37 0.075 gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 37 0.075 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 36 0.098 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 36 0.098 gi|48762934 alpha 2 type I collagen [Homo sapiens] 36 0.13 gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ... 36 0.13 gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ... 36 0.13 gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ... 36 0.13 gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] 35 0.22 gi|33286446 opioid growth factor receptor [Homo sapiens] 35 0.29 gi|118498339 EMI domain containing 2 [Homo sapiens] 35 0.29 gi|239754674 PREDICTED: hypothetical protein [Homo sapiens] 34 0.37 gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] 34 0.37 gi|38373671 SEC24-related protein C [Homo sapiens] 34 0.37 gi|38373669 SEC24-related protein C [Homo sapiens] 34 0.37 >gi|7662002 ER degradation enhancer, mannosidase alpha-like 1 [Homo sapiens] Length = 657 Score = 1358 bits (3515), Expect = 0.0 Identities = 657/657 (100%), Positives = 657/657 (100%) Query: 1 MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV 60 MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV Sbjct: 1 MQWRALVLGLVLLRLGLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPV 60 Query: 61 GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG 120 GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG Sbjct: 61 GRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSG 120 Query: 121 AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG 180 AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG Sbjct: 121 AFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLG 180 Query: 181 NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI 240 NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI Sbjct: 181 NYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRI 240 Query: 241 ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE 300 ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE Sbjct: 241 ITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNE 300 Query: 301 TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG 360 TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG Sbjct: 301 TCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG 360 Query: 361 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY 420 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY Sbjct: 361 KQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLY 420 Query: 421 VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL 480 VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL Sbjct: 421 VNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQL 480 Query: 481 QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK 540 QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK Sbjct: 481 QAPDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDK 540 Query: 541 STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS 600 STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS Sbjct: 541 STEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIVSVDEHLRELPWKEFFS 600 Query: 601 EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI 657 EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI Sbjct: 601 EEGGQDQGGKSVHRPKPHELKVINSSSNCNRVPDERRYSLPLKSIYMRQIDQMVGLI 657 >gi|163310725 ER degradation enhancer, mannosidase alpha-like 3 [Homo sapiens] Length = 932 Score = 384 bits (986), Expect = e-106 Identities = 208/454 (45%), Positives = 284/454 (62%), Gaps = 22/454 (4%) Query: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196 MF Y NYM HA+P DEL P+ CRGR + +PS +++D LG +SLTL+D+LDTL ++ Sbjct: 59 MFDHAYGNYMEHAYPADELMPLTCRGRVRGQ-EPSRGDVDDALGKFSLTLIDSLDTLVVL 117 Query: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256 + EF+ AV+ V+ V+ D D V VFE IRVLG LL H + K+ M + Y Sbjct: 118 NKTKEFEDAVRKVLRDVNLDNDVVVSVFETNIRVLGGLLGGHSLAIMLKEKGEYM--QWY 175 Query: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV-PPD----TNNETCTAGAGSLLV 311 ++ELL MA L +LLPAF NT +G+PYPR+NLK G+ P+ T +TCTA AG+L++ Sbjct: 176 NDELLQMAKQLGYKLLPAF-NTTSGLPYPRINLKFGIRKPEARTGTETDTCTACAGTLIL 234 Query: 312 EFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDS 371 EF LSR G + FE AR+A+ LW R + L+G +NI TG WV K SG+GAG+DS Sbjct: 235 EFAALSRFTGATIFEEYARKALDFLWEKRQRSSNLVGVTINIHTGDWVRKDSGVGAGIDS 294 Query: 372 FYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQL- 430 +YEYLLK+Y+L G+ LE FN Y +I Y+ PPL ++V++ L Sbjct: 295 YYEYLLKAYVLLGDDSFLERFNTHYDAIMRYI-----------SQPPLLLDVHIHKPMLN 343 Query: 431 MNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDVLFYPL 490 TW+D+L AFFPGLQVL GD+ AI H Y + K++ LPE + + +PL Sbjct: 344 ARTWMDALLAFFPGLQVLKGDIRPAIETHEMLYQVIKKHNFLPEAFTTDFRV-HWAQHPL 402 Query: 491 RPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFF 550 RPE ESTY LY+AT +P+YL VG ++++L KY +V CG+A + V S EDRM+SFF Sbjct: 403 RPEFAESTYFLYKATGDPYYLEVGKTLIENLNKYARVPCGFAAMKDVRTGSHEDRMDSFF 462 Query: 551 LSETCKYLYLLFDEDNPVHKSGTRYMFTTEGHIV 584 L+E KYLYLLF + + Y+FTTE H++ Sbjct: 463 LAEMFKYLYLLFADKEDIIFDIEDYIFTTEAHLL 496 >gi|222537737 ER degradation enhancer, mannosidase alpha-like 2 isoform 1 [Homo sapiens] Length = 578 Score = 355 bits (911), Expect = 7e-98 Identities = 214/525 (40%), Positives = 305/525 (58%), Gaps = 64/525 (12%) Query: 128 AQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLV 187 A R+ + MF YD+Y+ +AFP DEL P+ C G +D G++SLTL+ Sbjct: 33 AHYRERVKAMFYHAYDSYLENAFPFDELRPLTCDG-------------HDTWGSFSLTLI 79 Query: 188 DALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQP 247 DALDTL I+GN SEFQ+ V+++ ++V FD D VFE IRV+G LLSAH + SK+ Sbjct: 80 DALDTLLILGNVSEFQRVVEVLQDSVDFDIDVNASVFETNIRVVGGLLSAHLL---SKKA 136 Query: 248 FGDMTIK-DYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCTAGA 306 ++ LL MA + A +LLPAF+ T TG+PY VNL GV P TCTAG Sbjct: 137 GVEVEAGWPCSGPLLRMAEEAARKLLPAFQ-TPTGMPYGTVNLLHGVNPGETPVTCTAGI 195 Query: 307 GSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLG 366 G+ +VEF LS L GD FE VAR A+ LW RS D GL+GN +++ TG WV + +G+G Sbjct: 196 GTFIVEFATLSSLTGDPVFEDVARVALMRLWESRS-DIGLVGNHIDVLTGKWVAQDAGIG 254 Query: 367 AGLDSFYEYLLKSYILFGEKEDLEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMF 426 AG+DS++EYL+K IL +K+ + MF ++I+NY R Y+ V M+ Sbjct: 255 AGVDSYFEYLVKGAILLQDKKLMAMFLEYNKAIRNYTRFD-----------DWYLWVQMY 303 Query: 427 SGQLMNTWIDSLQAFFPGLQVLIGDVEDAICLHAFYYAIWKRYGALPERYN----WQLQA 482 G + SL+A++PGLQ LIGD+++A+ YY +WK++G LPE YN + ++ Sbjct: 304 KGTVSMPVFQSLEAYWPGLQSLIGDIDNAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEK 363 Query: 483 PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKST 542 + YPLRPEL+ES LY+AT +P L +G D ++S+EK +KV+CG+AT+ + D Sbjct: 364 REG--YPLRPELIESAMYLYRATGDPTLLELGRDAVESIEKISKVECGFATIKDLRDHKL 421 Query: 543 EDRMESFFLSETCKYLYLLFDEDNPVHKSGTR-----------------YMFTTEGHIVS 585 ++RMESFFL+ET KYLYLLFD N +H +G+ Y+F TE H + Sbjct: 422 DNRMESFFLAETVKYLYLLFDPTNFIHNNGSTFDAVITPYGECILGAGGYIFNTEAHPID 481 Query: 586 -----VDEHLRELPW------KEFFSEEGGQDQGGKSVHRPKPHE 619 + L+E W +EF+S + + + K+ P E Sbjct: 482 PAALHCCQRLKEEQWEVEDLMREFYSLKRSRSKFQKNTVSSGPWE 526 >gi|222537739 ER degradation enhancer, mannosidase alpha-like 2 isoform 2 [Homo sapiens] Length = 541 Score = 328 bits (842), Expect = 7e-90 Identities = 203/498 (40%), Positives = 288/498 (57%), Gaps = 56/498 (11%) Query: 155 LNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVS 214 L P H GPD P + + +SLTL+DALDTL I+GN SEFQ+ V+++ ++V Sbjct: 15 LLPQHHGAPGPDGSAPDPAHYS-----FSLTLIDALDTLLILGNVSEFQRVVEVLQDSVD 69 Query: 215 FDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIK-DYDNELLYMAHDLAVRLLP 273 FD D VFE IRV+G LLSAH + SK+ ++ LL MA + A +LLP Sbjct: 70 FDIDVNASVFETNIRVVGGLLSAHLL---SKKAGVEVEAGWPCSGPLLRMAEEAARKLLP 126 Query: 274 AFENTKTGIPYPRVNLKTGVPPDTNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAV 333 AF+ T TG+PY VNL GV P TCTAG G+ +VEF LS L GD FE VAR A+ Sbjct: 127 AFQ-TPTGMPYGTVNLLHGVNPGETPVTCTAGIGTFIVEFATLSSLTGDPVFEDVARVAL 185 Query: 334 KALWNLRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLEMFN 393 LW RS D GL+GN +++ TG WV + +G+GAG+DS++EYL+K IL +K+ + MF Sbjct: 186 MRLWESRS-DIGLVGNHIDVLTGKWVAQDAGIGAGVDSYFEYLVKGAILLQDKKLMAMFL 244 Query: 394 AAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVE 453 ++I+NY R Y+ V M+ G + SL+A++PGLQ LIGD++ Sbjct: 245 EYNKAIRNYTRFD-----------DWYLWVQMYKGTVSMPVFQSLEAYWPGLQSLIGDID 293 Query: 454 DAICLHAFYYAIWKRYGALPERYN----WQLQAPDVLFYPLRPELVESTYLLYQATKNPF 509 +A+ YY +WK++G LPE YN + ++ + YPLRPEL+ES LY+AT +P Sbjct: 294 NAMRTFLNYYTVWKQFGGLPEFYNIPQGYTVEKREG--YPLRPELIESAMYLYRATGDPT 351 Query: 510 YLHVGMDILQSLEKYTKVKCGYATLHHVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVH 569 L +G D ++S+EK +KV+CG+AT+ + D ++RMESFFL+ET KYLYLLFD N +H Sbjct: 352 LLELGRDAVESIEKISKVECGFATIKDLRDHKLDNRMESFFLAETVKYLYLLFDPTNFIH 411 Query: 570 KSGTR-----------------YMFTTEGHIVS-----VDEHLRELPW------KEFFSE 601 +G+ Y+F TE H + + L+E W +EF+S Sbjct: 412 NNGSTFDAVITPYGECILGAGGYIFNTEAHPIDPAALHCCQRLKEEQWEVEDLMREFYSL 471 Query: 602 EGGQDQGGKSVHRPKPHE 619 + + + K+ P E Sbjct: 472 KRSRSKFQKNTVSSGPWE 489 >gi|218749883 alpha 1,2-mannosidase [Homo sapiens] Length = 699 Score = 188 bits (477), Expect = 2e-47 Identities = 158/474 (33%), Positives = 230/474 (48%), Gaps = 66/474 (13%) Query: 137 MFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIM 196 +F+ + Y A+ DEL P+ + + ++ G LTL+DALDT+ I+ Sbjct: 256 VFLHAWKGYRKFAWGHDELKPV-------------SRSFSEWFG-LGLTLIDALDTMWIL 301 Query: 197 GNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDY 256 G EF++A K V + F+KD V +FE+TIR+LG LLSA+ + DS Sbjct: 302 GLRKEFEEARKWVSKKLHFEKDVDVNLFESTIRILGGLLSAYHLSGDSL----------- 350 Query: 257 DNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV--PPDTNNETCTAGAGSLLVEFG 314 L A D RL+PAF T + IPY VN+ TGV PP +++ A S+ +EF Sbjct: 351 ---FLRKAEDFGNRLMPAF-RTPSKIPYSDVNIGTGVAHPPRWTSDSTVAEVTSIQLEFR 406 Query: 315 ILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVG-KQSGLGAGLDSFY 373 LSRL GD F+ + + + L GL+ +N +G + LGA DS+Y Sbjct: 407 ELSRLTGDKKFQEAVEKVTQHIHGLSGKKDGLVPMFINTHSGLFTHLGVFTLGARADSYY 466 Query: 374 EYLLKSYILFGEKED--LEMFNAAYQSIQNYLRRGREACNEGEGDPPLYVNVNMFSGQLM 431 EYLLK +I G++E LE + A + ++ +L R +P V + Sbjct: 467 EYLLKQWIQGGKQETQLLEDYVEAIEGVRTHLLR--------HSEPSKLTFVGELAHGRF 518 Query: 432 NTWIDSLQAFFPGLQVL-------IGDVEDAICLHAFYYAIWKRY--GALPERYNWQLQA 482 + +D L F PG L +E A L Y + ++ G PE ++ L Sbjct: 519 SAKMDHLVCFLPGTLALGVYHGLPASHMELAQELMETCYQMNRQMETGLSPEIVHFNLYP 578 Query: 483 P----DVLFYP------LRPELVESTYLLYQATKNPFYLHVGMDILQSLEKYTKVKC-GY 531 DV P LRPE VES + LY+ T + Y G +ILQS ++T+V GY Sbjct: 579 QPGRRDVEVKPADRHNLLRPETVESLFYLYRVTGDRKYQDWGWEILQSFSRFTRVPSGGY 638 Query: 532 ATLHHVID---KSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEGH 582 +++++V D D+MESFFL ET KYL+LLF +D P S Y+F TE H Sbjct: 639 SSINNVQDPQKPEPRDKMESFFLGETLKYLFLLFSDD-PNLLSLDAYVFNTEAH 691 >gi|5729913 mannosidase, alpha, class 1A, member 2 [Homo sapiens] Length = 641 Score = 175 bits (444), Expect = 1e-43 Identities = 154/503 (30%), Positives = 243/503 (48%), Gaps = 59/503 (11%) Query: 103 VLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRG 162 ++G RG P++ + R + R+ + M +DNY + + +EL PI +G Sbjct: 164 LVGIRGGDPEDNDIR-----------EKREKIKEMMKHAWDNYRTYGWGHNELRPIARKG 212 Query: 163 RGPDRGDPSNLNINDVLGNYSLTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQ 222 P+ S + T+VDALDTL IMG EF + + + + F +S V Sbjct: 213 HSPNIFGSSQMGA---------TIVDALDTLYIMGLHDEFLDGQRWIEDNLDFSVNSEVS 263 Query: 223 VFEATIRVLGSLLSAHRIITDSKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGI 282 VFE IR +G LL+A+ + G+ K A LA +LLPAF NT TGI Sbjct: 264 VFEVNIRFIGGLLAAYYL-------SGEEIFK-------IKAVQLAEKLLPAF-NTPTGI 308 Query: 283 PYPRVNLKTGVPPD----TNNETCTAGAGSLLVEFGILSRLLGDSTFEWVARRAVKALWN 338 P+ VNLK+GV + + + A G+L +EF LS L GD T+ + ++ L Sbjct: 309 PWAMVNLKSGVGRNWGWASAGSSILAEFGTLHMEFIHLSYLTGDLTY-YKKVMHIRKLLQ 367 Query: 339 LRSNDTGLLGNVVNIQTGHWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAA 395 GL N +N +TG W + +G DSFYEYLLK++ L +K D E M++ A Sbjct: 368 KMDRPNGLYPNYLNPRTGRWGQYHTSVGGLGDSFYEYLLKAW-LMSDKTDHEARKMYDDA 426 Query: 396 YQSIQNYL----RRGREACNEGEGD--PPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLI 449 ++I+ +L R G E + ++ F+G + D +A G + + Sbjct: 427 IEAIEKHLIKKSRGGLTFIGEWKNGHLEKKMGHLACFAGGMFALGADGSRADKAGHYLEL 486 Query: 450 GDVEDAICLHAFYYAIWKRYGALPERYNWQLQAPDV----LFYPLRPELVESTYLLYQAT 505 G E A H Y + G +++ ++A V +Y LRPE++E+ + L++ T Sbjct: 487 G-AEIARTCHESYDRTALKLGPESFKFDGAVEAVAVRQAEKYYILRPEVIETYWYLWRFT 545 Query: 506 KNPFYLHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFD 563 +P Y G + ++EKY +V G++ + V + +D +SFFL+ET KYLYLLF Sbjct: 546 HDPRYRQWGWEAALAIEKYCRVNGGFSGVKDVYSSTPTHDDVQQSFFLAETLKYLYLLFS 605 Query: 564 EDNPVHKSGTRYMFTTEGHIVSV 586 D+ + ++F TE H + V Sbjct: 606 GDDLLPLD--HWVFNTEAHPLPV 626 >gi|24497519 mannosidase, alpha, class 1A, member 1 [Homo sapiens] Length = 653 Score = 164 bits (415), Expect = 2e-40 Identities = 138/485 (28%), Positives = 235/485 (48%), Gaps = 65/485 (13%) Query: 129 QMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYSLTLVD 188 + R + M ++NY +A+ +EL PI +G S+ ++ G T+VD Sbjct: 194 EKRAKIKEMMKHAWNNYKGYAWGLNELKPI-------SKGGHSSSLFGNIKG---ATIVD 243 Query: 189 ALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITDSKQPF 248 ALDTL IM EF++A V + F+ ++ + VFE IR +G LLSA+ + ++ F Sbjct: 244 ALDTLFIMEMKHEFEEAKSWVEENLDFNVNAEISVFEVNIRFVGGLLSAYYL--SGEEIF 301 Query: 249 GDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGV----PPDTNNETCTA 304 + +L V+LLPAF +T +GIP+ +N+K+G+ P + + A Sbjct: 302 RKKAV------------ELGVKLLPAF-HTPSGIPWALLNMKSGIGRNWPWASGGSSILA 348 Query: 305 GAGSLLVEFGILSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTGHWVGKQSG 364 G+L +EF LS L G+ F ++ + N GL N +N +G W Sbjct: 349 EFGTLHLEFMHLSHLSGNPIFAEKVMN-IRTVLNKLEKPQGLYPNYLNPSSGQWGQHHVS 407 Query: 365 LGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEGEGDPPLYV 421 +G DSFYEYLLK++ L +K DLE M+ A Q+I+ +L R + Sbjct: 408 VGGLGDSFYEYLLKAW-LMSDKTDLEAKKMYFDAVQAIETHLIRKSSSG---------LT 457 Query: 422 NVNMFSGQLMNTWIDSLQAFFPGLQVLIGD--------------VEDAICLHAFYYAIWK 467 + + G L+ + L F G+ L D E A H Y + Sbjct: 458 YIAEWKGGLLEHKMGHLTCFAGGMFALGADAAPEGMAQHYLELGAEIARTCHESYNRTFM 517 Query: 468 RYGALPERYNWQLQA----PDVLFYPLRPELVESTYLLYQATKNPFYLHVGMDILQSLEK 523 + G R++ ++A + +Y LRPE++E+ +++ T +P Y + +++LE Sbjct: 518 KLGPEAFRFDGGVEAIATRQNEKYYILRPEVMETYMYMWRLTHDPKYRKWAWEAVEALEN 577 Query: 524 YTKVKCGYATLH--HVIDKSTEDRMESFFLSETCKYLYLLFDEDNPVHKSGTRYMFTTEG 581 + +V GY+ L +++ +S +D +SFFL+ET KYLYL+F +D+ + ++F +E Sbjct: 578 HCRVNGGYSGLRDVYLLHESYDDVQQSFFLAETLKYLYLIFSDDDLLPLE--HWIFNSEA 635 Query: 582 HIVSV 586 H++ + Sbjct: 636 HLLPI 640 >gi|9966903 mannosidase, alpha, class 1C, member 1 [Homo sapiens] Length = 630 Score = 157 bits (398), Expect = 2e-38 Identities = 150/499 (30%), Positives = 232/499 (46%), Gaps = 86/499 (17%) Query: 125 QLRAQMRDLARGMFVFGYDNYMAHAFPQDELNPIHCRGRGPDRGDPSNLNINDVLGNYS- 183 Q+RAQ R+ + M F + +Y +A ++EL P+ G ++ G S Sbjct: 170 QVRAQ-REKIKEMMQFAWQSYKRYAMGKNELRPLTKDGYE-----------GNMFGGLSG 217 Query: 184 LTLVDALDTLAIMGNSSEFQKAVKLVINTVSFDKDSTVQVFEATIRVLGSLLSAHRIITD 243 T++D+LDTL +M EFQ+A V + + +FE IR +G LLSA + Sbjct: 218 ATVIDSLDTLYLMELKEEFQEAKAWVGESFHLNVSGEASLFEVNIRYIGGLLSAFYL--T 275 Query: 244 SKQPFGDMTIKDYDNELLYMAHDLAVRLLPAFENTKTGIPYPRVNLKTGVPPDTNNETCT 303 ++ F I+ L +LLPAF NT TGIP V+ K+G N T Sbjct: 276 GEEVFRIKAIR------------LGEKLLPAF-NTPTGIPKGVVSFKSG-----NWGWAT 317 Query: 304 AGAGSLLVEFGI-------LSRLLGDSTFEWVARRAVKALWNLRSNDTGLLGNVVNIQTG 356 AG+ S+L EFG L+ L G+ F R K L + GL N ++ +G Sbjct: 318 AGSSSILAEFGSLHLEFLHLTELSGNQVFAEKVRNIRKVLRKI-EKPFGLYPNFLSPVSG 376 Query: 357 HWVGKQSGLGAGLDSFYEYLLKSYILFGEKEDLE---MFNAAYQSIQNYLRRGREACNEG 413 +WV +G DSFYEYL+KS+++ G K D+E M+ A ++I+ YL Sbjct: 377 NWVQHHVSVGGLGDSFYEYLIKSWLMSG-KTDMEAKNMYYEALEAIETYLL--------- 426 Query: 414 EGDPPLYVNVNMFSGQLMNTWIDSLQAFFPGLQVLIGDVEDA----------------IC 457 P + + G +++ + L F G+ L EDA Sbjct: 427 NVSPGGLTYIAEWRGGILDHKMGHLACFSGGMIAL--GAEDAKEEKRAHYRELAAQITKT 484 Query: 458 LHAFYYAIWKRYGALPERYNWQLQAPDVL-------FYPLRPELVESTYLLYQATKNPFY 510 H Y + G PE + W + + +Y LRPE+VES L++ T NP Y Sbjct: 485 CHESYARSDTKLG--PEAF-WFNSGREAVATQLSESYYILRPEVVESYMYLWRQTHNPIY 541 Query: 511 LHVGMDILQSLEKYTKVKCGYATLHHVIDKST--EDRMESFFLSETCKYLYLLFDEDNPV 568 G +++ +LEKY + + G++ + V + +++ +SFFL+ET KYLYLLF ED+ + Sbjct: 542 REWGWEVVLALEKYCRTEAGFSGIQDVYSSTPNHDNKQQSFFLAETLKYLYLLFSEDDLL 601 Query: 569 HKSGTRYMFTTEGHIVSVD 587 S ++F TE H + V+ Sbjct: 602 --SLEDWVFNTEAHPLPVN 618 >gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo sapiens] Length = 940 Score = 45.4 bits (106), Expect = 2e-04 Identities = 30/73 (41%), Positives = 32/73 (43%), Gaps = 8/73 (10%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKA-PRRPGPGMCGPANWGYVLGGR 107 P GP P GP G PGG GP L PP PR P GPG P G + GG Sbjct: 644 PPGPGGPMPGPHGGPGGPVGPRLLGPP-----PPPRGGDPFWDGPG--DPMRGGPMRGGP 696 Query: 108 GRGPDEYEKRYSG 120 G GP Y + G Sbjct: 697 GPGPGPYHRGRGG 709 >gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo sapiens] Length = 1487 Score = 38.9 bits (89), Expect = 0.015 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%) Query: 47 RSPDGPASPTS--------GPVGRPG-----GVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93 R P GP P+ GP+G PG G +GP+ PPG P P PGPG Sbjct: 1163 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG--PPGNPGPPGP---PGPPGPG 1217 Query: 94 MCGPANWGYVLGGRGRGPD 112 + A G LG R +GPD Sbjct: 1218 IDMSAFAG--LGPREKGPD 1234 Score = 36.2 bits (82), Expect = 0.098 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 18/99 (18%) Query: 47 RSPDGPASPT--SGPVGRPGGVSGPSWLQPPGTGAAQSPR---------KAPRRPG-PGM 94 R P GP P +GP G PG P PPG A + AP PG PG Sbjct: 1016 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1075 Query: 95 CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDL 133 GPA G G+ D E G P A R + Sbjct: 1076 PGPA------GPTGKQGDRGEAGAQGPMGPSGPAGARGI 1108 Score = 34.3 bits (77), Expect = 0.37 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 15/136 (11%) Query: 47 RSPDGPASPT-----SGPVGRPGGVSGPSWLQPPGTGAAQSPRKA------PRRPG-PGM 94 R GP T +G VG PG P PPG P+ A P R G PG+ Sbjct: 887 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 946 Query: 95 CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDE 154 GPA G +G D+ G PQ A R + G + P E Sbjct: 947 QGPAG---PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 1003 Query: 155 LNPIHCRGRGPDRGDP 170 G DRG P Sbjct: 1004 PGKQGAPGASGDRGPP 1019 Score = 32.7 bits (73), Expect = 1.1 Identities = 41/147 (27%), Positives = 51/147 (34%), Gaps = 23/147 (15%) Query: 49 PDGPASPTSGP--VGRPG--------GVSGPSWLQ----PPGTGAAQSPRKAPRRPG--- 91 P GP P GP G PG G GP Q PGT + P A PG Sbjct: 355 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 414 Query: 92 -PGMCGPANWGYVLGGRG----RGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYM 146 PG G A + G G RGP + +G P+ + +A G Sbjct: 415 IPGAKGSAGAPGIAGAPGFPGPRGPPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 473 Query: 147 AHAFPQDELNPIHCRGRGPDRGDPSNL 173 A PQ P G+ RG+P + Sbjct: 474 GPAGPQGAPGPAGEEGKRGARGEPGGV 500 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 46 LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG-PGMCGPAN 99 ++ P GP P GP G PG G G P PG PR P PG PG G A Sbjct: 199 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 258 Query: 100 WGYVLGGRG 108 G RG Sbjct: 259 KPGKAGERG 267 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 10/79 (12%) Query: 57 SGPVGRPG--GVSGPSW-LQPPGTGAAQSPRKAPRR------PGP-GMCGPANWGYVLGG 106 +GP+G PG G +G + PPG + R AP PGP G GP G Sbjct: 788 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 847 Query: 107 RGRGPDEYEKRYSGAFPPQ 125 +G + +K +GA PQ Sbjct: 848 KGEQGEAGQKGDAGAPGPQ 866 Score = 32.0 bits (71), Expect = 1.9 Identities = 27/82 (32%), Positives = 28/82 (34%), Gaps = 18/82 (21%) Query: 35 QRFPLSFGFQRLRSPDGPASPTSGP--VGRPGGVSGPSWLQP------------PGTGAA 80 Q P GFQ L P GP P G PG P + P PG Sbjct: 656 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 715 Query: 81 QSPRKAPRRPG----PGMCGPA 98 Q PR P PG G GPA Sbjct: 716 QGPRGLPGTPGTDGPKGASGPA 737 Score = 30.8 bits (68), Expect = 4.1 Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 14/63 (22%) Query: 47 RSPDGPASPTSGPVGRPGGVSGPSWLQPPG-------TGA-----AQSPRKAPRRPG-PG 93 R DG P +GP G G GP + PG TGA AQ PR P PG PG Sbjct: 344 RGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 402 Query: 94 MCG 96 G Sbjct: 403 PAG 405 Score = 30.8 bits (68), Expect = 4.1 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Query: 58 GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGP 97 GP+G PG P PG P+ AP GP G+ GP Sbjct: 501 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 541 Score = 30.4 bits (67), Expect = 5.4 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 9/76 (11%) Query: 42 GFQRLRSPDG-PASP-TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP------- 92 G Q L+ P G P +P T GP G G P PPG R A GP Sbjct: 711 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 770 Query: 93 GMCGPANWGYVLGGRG 108 G GP GGRG Sbjct: 771 GEKGPEGAPGKDGGRG 786 >gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo sapiens] Length = 1418 Score = 38.9 bits (89), Expect = 0.015 Identities = 30/79 (37%), Positives = 36/79 (45%), Gaps = 20/79 (25%) Query: 47 RSPDGPASPTS--------GPVGRPG-----GVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93 R P GP P+ GP+G PG G +GP+ PPG P P PGPG Sbjct: 1094 RGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAG--PPGNPGPPGP---PGPPGPG 1148 Query: 94 MCGPANWGYVLGGRGRGPD 112 + A G LG R +GPD Sbjct: 1149 IDMSAFAG--LGPREKGPD 1165 Score = 36.2 bits (82), Expect = 0.098 Identities = 32/99 (32%), Positives = 36/99 (36%), Gaps = 18/99 (18%) Query: 47 RSPDGPASPT--SGPVGRPGGVSGPSWLQPPGTGAAQSPR---------KAPRRPG-PGM 94 R P GP P +GP G PG P PPG A + AP PG PG Sbjct: 947 RGPPGPVGPPGLTGPAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGS 1006 Query: 95 CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDL 133 GPA G G+ D E G P A R + Sbjct: 1007 PGPA------GPTGKQGDRGEAGAQGPMGPSGPAGARGI 1039 Score = 34.3 bits (77), Expect = 0.37 Identities = 39/136 (28%), Positives = 46/136 (33%), Gaps = 15/136 (11%) Query: 47 RSPDGPASPT-----SGPVGRPGGVSGPSWLQPPGTGAAQSPRKA------PRRPG-PGM 94 R GP T +G VG PG P PPG P+ A P R G PG+ Sbjct: 818 RGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEPGL 877 Query: 95 CGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQDE 154 GPA G +G D+ G PQ A R + G + P E Sbjct: 878 QGPAG---PPGEKGEPGDDGPSGAEGPPGPQGLAGQRGIVGLPGQRGERGFPGLPGPSGE 934 Query: 155 LNPIHCRGRGPDRGDP 170 G DRG P Sbjct: 935 PGKQGAPGASGDRGPP 950 Score = 32.7 bits (73), Expect = 1.1 Identities = 41/147 (27%), Positives = 51/147 (34%), Gaps = 23/147 (15%) Query: 49 PDGPASPTSGP--VGRPG--------GVSGPSWLQ----PPGTGAAQSPRKAPRRPG--- 91 P GP P GP G PG G GP Q PGT + P A PG Sbjct: 286 PPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPGPAGASGNPGTDG 345 Query: 92 -PGMCGPANWGYVLGGRG----RGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYM 146 PG G A + G G RGP + +G P+ + +A G Sbjct: 346 IPGAKGSAGAPGIAGAPGFPGPRGPPG-PQGATGPLGPKGQTGEPGIAGFKGEQGPKGEP 404 Query: 147 AHAFPQDELNPIHCRGRGPDRGDPSNL 173 A PQ P G+ RG+P + Sbjct: 405 GPAGPQGAPGPAGEEGKRGARGEPGGV 431 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/69 (37%), Positives = 28/69 (40%), Gaps = 6/69 (8%) Query: 46 LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG-PGMCGPAN 99 ++ P GP P GP G PG G G P PG PR P PG PG G A Sbjct: 130 MQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAG 189 Query: 100 WGYVLGGRG 108 G RG Sbjct: 190 KPGKAGERG 198 Score = 32.3 bits (72), Expect = 1.4 Identities = 26/79 (32%), Positives = 35/79 (44%), Gaps = 10/79 (12%) Query: 57 SGPVGRPG--GVSGPSW-LQPPGTGAAQSPRKAPRR------PGP-GMCGPANWGYVLGG 106 +GP+G PG G +G + PPG + R AP PGP G GP G Sbjct: 719 TGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGPPGADGQPGA 778 Query: 107 RGRGPDEYEKRYSGAFPPQ 125 +G + +K +GA PQ Sbjct: 779 KGEQGEAGQKGDAGAPGPQ 797 Score = 32.0 bits (71), Expect = 1.9 Identities = 27/82 (32%), Positives = 28/82 (34%), Gaps = 18/82 (21%) Query: 35 QRFPLSFGFQRLRSPDGPASPTSGP--VGRPGGVSGPSWLQP------------PGTGAA 80 Q P GFQ L P GP P G PG P + P PG Sbjct: 587 QGAPGPSGFQGLPGPPGPPGEGGKPGDQGVPGEAGAPGLVGPRGERGFPGERGSPGAQGL 646 Query: 81 QSPRKAPRRPG----PGMCGPA 98 Q PR P PG G GPA Sbjct: 647 QGPRGLPGTPGTDGPKGASGPA 668 Score = 30.8 bits (68), Expect = 4.1 Identities = 25/63 (39%), Positives = 27/63 (42%), Gaps = 14/63 (22%) Query: 47 RSPDGPASPTSGPVGRPGGVSGPSWLQPPG-------TGA-----AQSPRKAPRRPG-PG 93 R DG P +GP G G GP + PG TGA AQ PR P PG PG Sbjct: 275 RGNDGQPGP-AGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPRGEPGTPGSPG 333 Query: 94 MCG 96 G Sbjct: 334 PAG 336 Score = 30.8 bits (68), Expect = 4.1 Identities = 16/41 (39%), Positives = 19/41 (46%), Gaps = 1/41 (2%) Query: 58 GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGP 97 GP+G PG P PG P+ AP GP G+ GP Sbjct: 432 GPIGPPGERGAPGNRGFPGQDGLAGPKGAPGERGPSGLAGP 472 Score = 30.4 bits (67), Expect = 5.4 Identities = 27/76 (35%), Positives = 29/76 (38%), Gaps = 9/76 (11%) Query: 42 GFQRLRSPDG-PASP-TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP------- 92 G Q L+ P G P +P T GP G G P PPG R A GP Sbjct: 642 GAQGLQGPRGLPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDV 701 Query: 93 GMCGPANWGYVLGGRG 108 G GP GGRG Sbjct: 702 GEKGPEGAPGKDGGRG 717 >gi|119508426 alpha 3 type IX collagen [Homo sapiens] Length = 684 Score = 38.1 bits (87), Expect = 0.026 Identities = 30/74 (40%), Positives = 36/74 (48%), Gaps = 8/74 (10%) Query: 42 GFQRLRSPDGPASPTSGPVGRPG--GVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPA 98 G QR+ P P P GP G+PG G+ G + PPG P+ AP +PG PG G Sbjct: 24 GAQRVGLPGPPGPP--GPPGKPGQDGIDGEAG--PPGLPGPPGPKGAPGKPGKPGEAGLP 79 Query: 99 NWGYVLGGRGR-GP 111 V G GR GP Sbjct: 80 GLPGVDGLTGRDGP 93 >gi|116008152 alpha 1 type XV collagen precursor [Homo sapiens] Length = 1388 Score = 37.0 bits (84), Expect = 0.058 Identities = 26/74 (35%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Query: 44 QRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG----PGMCGPAN 99 Q LR P GP P P G PG ++ PPG+ P P PG PG+ G Sbjct: 615 QLLRGPPGPPGPPGLP-GIPGKPGTDVFMGPPGSPGEDGPAGEPGPPGPEGQPGVDGATG 673 Query: 100 WGYVLGGRG-RGPD 112 + G +G RGP+ Sbjct: 674 LPGMKGEKGARGPN 687 >gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo sapiens] Length = 647 Score = 37.0 bits (84), Expect = 0.058 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 8/66 (12%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLG--- 105 P G GP PGG P +P TG Q P PR P GPA+ G+ G Sbjct: 406 PSGAGPAREGPAAWPGGAPTPPHARP--TGRRQDPEPGPRAP---RGGPASSGWHAGSAA 460 Query: 106 GRGRGP 111 GRG P Sbjct: 461 GRGWDP 466 >gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo sapiens] Length = 647 Score = 37.0 bits (84), Expect = 0.058 Identities = 25/66 (37%), Positives = 28/66 (42%), Gaps = 8/66 (12%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLG--- 105 P G GP PGG P +P TG Q P PR P GPA+ G+ G Sbjct: 406 PSGAGPAREGPAAWPGGAPTPPHARP--TGRRQDPEPGPRAP---RGGPASSGWHAGSAA 460 Query: 106 GRGRGP 111 GRG P Sbjct: 461 GRGWDP 466 >gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens] Length = 1838 Score = 36.6 bits (83), Expect = 0.075 Identities = 25/58 (43%), Positives = 30/58 (51%), Gaps = 11/58 (18%) Query: 47 RSPDGPASPTSGPVGRPG--GVSGPSWLQ-PPGTGAAQSPRKAPRRPGP----GMCGP 97 R P GPA GP GR G G G + L+ PPG P+ AP +PGP G+ GP Sbjct: 1392 RGPPGPA----GPEGRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGP 1445 Score = 36.2 bits (82), Expect = 0.098 Identities = 42/141 (29%), Positives = 51/141 (36%), Gaps = 18/141 (12%) Query: 42 GFQRLRSPDGPASPTS--GPVGRPGGVSGPSWLQPPGTGAAQSP---RKAPRRPGP---- 92 G Q L P G P GP+G+PG P PPG + P + PGP Sbjct: 727 GAQGLPGPQGAIGPPGEKGPLGKPGLPGMPGADGPPGHPGKEGPPGEKGGQGPPGPQGPI 786 Query: 93 GMCGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQMRDLARGMFVFGYDNYMAHAFPQ 152 G GP G RG + EK G FP M + G + P+ Sbjct: 787 GYPGPRGVKGADGIRGLKGTKGEKGEDG-FP--------GFKGDMGIKGDRGEIGPPGPR 837 Query: 153 DELNPIHCRGRGPDRGDPSNL 173 E P +GRG GDP L Sbjct: 838 GEDGPEGPKGRGGPNGDPGPL 858 Score = 31.2 bits (69), Expect = 3.2 Identities = 28/77 (36%), Positives = 30/77 (38%), Gaps = 10/77 (12%) Query: 42 GFQRLRSPDGPASP-----TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMC 95 GF R GP GP G PG P P G A P P RPGP G Sbjct: 1057 GFPGDRGLPGPVGALGLKGNEGPPGPPGPAGSPGERGPAG---AAGPIGIPGRPGPQGPP 1113 Query: 96 GPANWGYVLGGRG-RGP 111 GPA G +G +GP Sbjct: 1114 GPAGEKGAPGEKGPQGP 1130 Score = 30.8 bits (68), Expect = 4.1 Identities = 25/70 (35%), Positives = 28/70 (40%), Gaps = 18/70 (25%) Query: 46 LRSPDGPASPTS--GPVGRPG--GVSG-PSWLQPPGTGAAQSPRKAPRRPG--------- 91 LR P GP T GPVG PG G+ G P + P G Q P +PG Sbjct: 557 LRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQGPRGVQGPPGPAGKPGRRGRAGSDG 616 Query: 92 ----PGMCGP 97 PG GP Sbjct: 617 ARGMPGQTGP 626 Score = 30.8 bits (68), Expect = 4.1 Identities = 25/81 (30%), Positives = 31/81 (38%), Gaps = 16/81 (19%) Query: 49 PDGPASPTS-----GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYV 103 P GP P+ GP G PGG+ P G P +A PG GP Sbjct: 1253 PPGPRGPSGAPGADGPQGPPGGIGNPG-----AVGEKGEPGEAGEPGLPGEGGPP----- 1302 Query: 104 LGGRGRGPDEYEKRYSGAFPP 124 G +G ++ E SGA P Sbjct: 1303 -GPKGERGEKGESGPSGAAGP 1322 >gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] Length = 2944 Score = 36.6 bits (83), Expect = 0.075 Identities = 28/69 (40%), Positives = 31/69 (44%), Gaps = 10/69 (14%) Query: 47 RSPDGPASPTS--GPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPANWGYV 103 R P GPA G GRPG GP PPG Q + P RPG P + GPA V Sbjct: 1497 RGPPGPAGSRGLPGVAGRPGA-KGPEG--PPGPTGRQGEKGEPGRPGDPAVVGPA----V 1549 Query: 104 LGGRGRGPD 112 G +G D Sbjct: 1550 AGPKGEKGD 1558 Score = 32.7 bits (73), Expect = 1.1 Identities = 29/77 (37%), Positives = 32/77 (41%), Gaps = 8/77 (10%) Query: 42 GFQRLRSPDGPASPTS-GPVGRPGGVSGPSWLQ----PPGTGAAQSPRKAPRRPG-PGMC 95 G Q R P G P GP G PG GP L PPG + P RPG PG Sbjct: 1569 GVQGERGPPGLVLPGDPGPKGDPGD-RGPIGLTGRAGPPGDSGPPGEKGDPGRPGPPGPV 1627 Query: 96 GPANWGYVLGGRG-RGP 111 GP +G +G GP Sbjct: 1628 GPRGRDGEVGEKGDEGP 1644 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 36.2 bits (82), Expect = 0.098 Identities = 30/85 (35%), Positives = 33/85 (38%), Gaps = 18/85 (21%) Query: 42 GFQRLRSPDGPASP--------TSGPVGRPG--------GVSGPSWLQ-PPGTGAAQSPR 84 GF R P GP P SG G PG G GP +Q PPG + R Sbjct: 410 GFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEPGPVGVQGPPGPAGEEGKR 469 Query: 85 KAPRRPGP-GMCGPANWGYVLGGRG 108 A PGP G+ GP G RG Sbjct: 470 GARGEPGPTGLPGPPGERGGPGSRG 494 Score = 35.4 bits (80), Expect = 0.17 Identities = 20/54 (37%), Positives = 24/54 (44%), Gaps = 5/54 (9%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP----GMCGPA 98 P GP P +GP G PG V P G ++ P+ PGP G GPA Sbjct: 333 PPGPTGP-AGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGAAGPA 385 Score = 34.7 bits (78), Expect = 0.29 Identities = 26/75 (34%), Positives = 28/75 (37%), Gaps = 8/75 (10%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG----PGMCGP 97 GFQ L P GP G G+PG P L PG A+ R P G PG GP Sbjct: 641 GFQGLPGPAGPP----GEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGP 696 Query: 98 ANWGYVLGGRGRGPD 112 G G D Sbjct: 697 RGANGAPGNDGAKGD 711 Score = 32.7 bits (73), Expect = 1.1 Identities = 28/78 (35%), Positives = 32/78 (41%), Gaps = 12/78 (15%) Query: 57 SGPVGRPG--------GVSGPSW-LQPPGTGAAQSPRKAPRRPGP-GMCGPANWGYVLGG 106 +GP+G PG G SGPS P G A R P PGP G GP G Sbjct: 766 TGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGA 825 Query: 107 RGRGPDEYEKRYSGAFPP 124 +G D K +G PP Sbjct: 826 KGEPGDAGAKGDAG--PP 841 Score = 30.4 bits (67), Expect = 5.4 Identities = 24/75 (32%), Positives = 28/75 (37%), Gaps = 15/75 (20%) Query: 49 PDGPASPTS-----GPVGRPGGVSGPSWLQPP---------GTGAAQSPRKAPRRPGP-G 93 P GP P GP G G P + PP G+ A P AP PGP G Sbjct: 894 PPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQG 953 Query: 94 MCGPANWGYVLGGRG 108 + G + G RG Sbjct: 954 IAGQRGVVGLPGQRG 968 Score = 30.0 bits (66), Expect = 7.1 Identities = 26/74 (35%), Positives = 31/74 (41%), Gaps = 11/74 (14%) Query: 47 RSPDGPASPTS-----GPVGRPG--GVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPA 98 + P GPA P GP G PG G+ GP+ PPG + P G PG G Sbjct: 619 QGPPGPAGPAGERGEQGPAGSPGFQGLPGPA--GPPGEAGKPGEQGVPGDLGAPGPSGAR 676 Query: 99 NWGYVLGGRG-RGP 111 G RG +GP Sbjct: 677 GERGFPGERGVQGP 690 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 36.2 bits (82), Expect = 0.098 Identities = 24/69 (34%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPANW 100 G+ P GP P G G PG P + PPG P P PG G GPA Sbjct: 171 GYPGPAGPPGPPGPP-GTSGHPGSPGSPGYQGPPGEPGQAGPSGPPGPPGAIGPSGPAGK 229 Query: 101 GYVLGGRGR 109 G GR Sbjct: 230 DGESGRPGR 238 Score = 35.4 bits (80), Expect = 0.17 Identities = 27/63 (42%), Positives = 28/63 (44%), Gaps = 6/63 (9%) Query: 49 PDGPASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRPGPGMCGPANWGYVLG 105 P GP PT GP G G G GP LQ PGTG P PGP G A G Sbjct: 616 PQGPPGPT-GPGGDKGDTGPPGPQGLQGLPGTGGPPGENGKPGEPGPK--GDAGAPGAPG 672 Query: 106 GRG 108 G+G Sbjct: 673 GKG 675 Score = 34.3 bits (77), Expect = 0.37 Identities = 20/50 (40%), Positives = 24/50 (48%), Gaps = 2/50 (4%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97 P GP P SGP G+ G P + PPG + R + PG PG GP Sbjct: 1138 PRGPVGP-SGPPGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGP 1186 Score = 30.4 bits (67), Expect = 5.4 Identities = 19/56 (33%), Positives = 21/56 (37%), Gaps = 4/56 (7%) Query: 38 PLSFGFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93 P GF + DG G G GG GP PPG P+ P GPG Sbjct: 575 PGVMGFPGPKGNDG----APGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPG 626 Score = 30.0 bits (66), Expect = 7.1 Identities = 21/47 (44%), Positives = 23/47 (48%), Gaps = 6/47 (12%) Query: 51 GPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGP 97 GP P SGP G+PG + P P G A P K R GPG GP Sbjct: 564 GPPGP-SGPRGQPGVMGFPG---PKGNDGA--PGKNGERGGPGGPGP 604 Score = 29.6 bits (65), Expect = 9.2 Identities = 19/60 (31%), Positives = 22/60 (36%), Gaps = 5/60 (8%) Query: 50 DGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGPANWGYVLGGRG 108 DGP GP G G P P G + +P G PG GP + G RG Sbjct: 902 DGPP----GPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARG 957 Score = 29.6 bits (65), Expect = 9.2 Identities = 18/51 (35%), Positives = 22/51 (43%), Gaps = 3/51 (5%) Query: 48 SPDGPASPTSGPVGRPGGVSGPSWLQPPG-TGAAQSPRKAPRRPGPGMCGP 97 +P P SP GP G+ G + P P G G + P K PG GP Sbjct: 1114 NPGAPGSP--GPAGQQGAIGSPGPAGPRGPVGPSGPPGKDGTSGHPGPIGP 1162 >gi|48762934 alpha 2 type I collagen [Homo sapiens] Length = 1366 Score = 35.8 bits (81), Expect = 0.13 Identities = 25/64 (39%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPGTGAA---QSPRKAPRRPG-PGMCGPANWGYVL 104 P GPA P SGP G+ G P + P G Q P P PG PG G + GY Sbjct: 1052 PRGPAGP-SGPAGKDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPPGVSGGGYDF 1110 Query: 105 GGRG 108 G G Sbjct: 1111 GYDG 1114 Score = 34.3 bits (77), Expect = 0.37 Identities = 24/69 (34%), Positives = 25/69 (36%), Gaps = 9/69 (13%) Query: 49 PDGPASPT--------SGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPAN 99 P GPA P SGPVG PG G AP PGP G+ GP Sbjct: 275 PAGPAGPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAAGLPGVAGAPGLPGPRGIPGPVG 334 Query: 100 WGYVLGGRG 108 G RG Sbjct: 335 AAGATGARG 343 Score = 32.7 bits (73), Expect = 1.1 Identities = 41/130 (31%), Positives = 49/130 (37%), Gaps = 41/130 (31%) Query: 42 GFQRLRSPDGPASPTSGPVGRPG--------GVSGPSWLQ----PPGTGAAQSP------ 83 GFQ L P GPA G VG+PG G+ GP+ + PPG A P Sbjct: 553 GFQGLPGPSGPA----GEVGKPGERGLHGEFGLPGPAGPRGERGPPGESGAAGPTGPIGS 608 Query: 84 RKAPRRPGP-------------GMCGPANWGYVLGGRGRGPDEYEKRYSGAFPPQLRAQM 130 R PGP G GP+ + G RG K G P LR ++ Sbjct: 609 RGPSGPPGPDGNKGEPGVVGAVGTAGPSGPSGLPGERGAAGIPGGKGEKG--EPGLRGEI 666 Query: 131 ----RDLARG 136 RD ARG Sbjct: 667 GNPGRDGARG 676 >gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo sapiens] Length = 1650 Score = 35.8 bits (81), Expect = 0.13 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 49 PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106 P+GPA P G PG V P PPG AP PG + P +G GG Sbjct: 317 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 374 Query: 107 RGRGP 111 +GP Sbjct: 375 GDKGP 379 Score = 35.8 bits (81), Expect = 0.13 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%) Query: 49 PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99 P GP PT GP G PG V P PPG G A+ R PG PG GP Sbjct: 1164 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1223 Query: 100 WGYVLGGRG-RGP 111 G G RGP Sbjct: 1224 ENGPPGPLGKRGP 1236 Score = 34.3 bits (77), Expect = 0.37 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%) Query: 42 GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90 GFQ P GP A+ +GP+G G G GP Q PGT + + P P Sbjct: 827 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 886 Query: 91 G-PGMCGPANWGYVLGGRG 108 G PG GPA G RG Sbjct: 887 GAPGKDGPAGLRGFPGERG 905 Score = 30.8 bits (68), Expect = 4.1 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 42 GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98 G Q L P G P GP G+PG P PPG + P GP G GP Sbjct: 569 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 628 Query: 99 NWGYVLGGRG 108 + G +G Sbjct: 629 GYPGPRGVKG 638 Score = 30.0 bits (66), Expect = 7.1 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97 G + P GP P P G G + PPG Q P A G PG GP Sbjct: 914 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 969 >gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo sapiens] Length = 1629 Score = 35.8 bits (81), Expect = 0.13 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 49 PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106 P+GPA P G PG V P PPG AP PG + P +G GG Sbjct: 296 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 353 Query: 107 RGRGP 111 +GP Sbjct: 354 GDKGP 358 Score = 35.8 bits (81), Expect = 0.13 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%) Query: 49 PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99 P GP PT GP G PG V P PPG G A+ R PG PG GP Sbjct: 1143 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1202 Query: 100 WGYVLGGRG-RGP 111 G G RGP Sbjct: 1203 ENGPPGPLGKRGP 1215 Score = 34.3 bits (77), Expect = 0.37 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%) Query: 42 GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90 GFQ P GP A+ +GP+G G G GP Q PGT + + P P Sbjct: 806 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 865 Query: 91 G-PGMCGPANWGYVLGGRG 108 G PG GPA G RG Sbjct: 866 GAPGKDGPAGLRGFPGERG 884 Score = 30.8 bits (68), Expect = 4.1 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 42 GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98 G Q L P G P GP G+PG P PPG + P GP G GP Sbjct: 548 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 607 Query: 99 NWGYVLGGRG 108 + G +G Sbjct: 608 GYPGPRGVKG 617 Score = 30.0 bits (66), Expect = 7.1 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97 G + P GP P P G G + PPG Q P A G PG GP Sbjct: 893 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 948 >gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo sapiens] Length = 1736 Score = 35.8 bits (81), Expect = 0.13 Identities = 23/65 (35%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 49 PDGPASPTSGP--VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPANWGYVLGG 106 P+GPA P G PG V P PPG AP PG + P +G GG Sbjct: 403 PEGPAGLIGPPGIQGNPGPVGDPGERGPPGRAGLPGSDGAPGPPGTSLMLPFRFG--SGG 460 Query: 107 RGRGP 111 +GP Sbjct: 461 GDKGP 465 Score = 35.8 bits (81), Expect = 0.13 Identities = 29/73 (39%), Positives = 30/73 (41%), Gaps = 10/73 (13%) Query: 49 PDGPASPTS--GPVGRPGGVSGPSWLQPPGTG------AAQSPRKAPRRPG-PGMCGPAN 99 P GP PT GP G PG V P PPG G A+ R PG PG GP Sbjct: 1250 PPGPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTG 1309 Query: 100 WGYVLGGRG-RGP 111 G G RGP Sbjct: 1310 ENGPPGPLGKRGP 1322 Score = 34.3 bits (77), Expect = 0.37 Identities = 29/79 (36%), Positives = 34/79 (43%), Gaps = 12/79 (15%) Query: 42 GFQRLRSPDGP--------ASPTSGPVGRPG--GVSGPSWLQP-PGTGAAQSPRKAPRRP 90 GFQ P GP A+ +GP+G G G GP Q PGT + + P P Sbjct: 913 GFQGKTGPPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPP 972 Query: 91 G-PGMCGPANWGYVLGGRG 108 G PG GPA G RG Sbjct: 973 GAPGKDGPAGLRGFPGERG 991 Score = 30.8 bits (68), Expect = 4.1 Identities = 23/70 (32%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 42 GFQRLRSPDGPASP--TSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPA 98 G Q L P G P GP G+PG P PPG + P GP G GP Sbjct: 655 GTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPPGHPGKEGPPGTKGNQGPSGPQGPL 714 Query: 99 NWGYVLGGRG 108 + G +G Sbjct: 715 GYPGPRGVKG 724 Score = 30.0 bits (66), Expect = 7.1 Identities = 19/57 (33%), Positives = 21/57 (36%), Gaps = 2/57 (3%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPG-PGMCGP 97 G + P GP P P G G + PPG Q P A G PG GP Sbjct: 1000 GLKGNEGPSGPPGPAGSP-GERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGP 1055 >gi|32964830 collagen, type VIII, alpha 2 [Homo sapiens] Length = 703 Score = 35.0 bits (79), Expect = 0.22 Identities = 37/108 (34%), Positives = 41/108 (37%), Gaps = 8/108 (7%) Query: 51 GPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKA-----PRRPG-PGMCGPANWGYVL 104 GPA P GP G PG P PPG G A P A P PG PG+ GP Sbjct: 469 GPAGPI-GPQGLPGLKGEPGLPGPPGEGRAGEPGTAGPTGPPGVPGSPGITGPPGPPGPP 527 Query: 105 GGRGRGPDEYEKRYSGAFPPQLRAQMRDLAR-GMFVFGYDNYMAHAFP 151 G G E +G P + L + G FG AHA P Sbjct: 528 GPPGAPGAFDETGIAGLHLPNGGVEGAVLGKGGKPQFGLGELSAHATP 575 Score = 32.7 bits (73), Expect = 1.1 Identities = 28/80 (35%), Positives = 32/80 (40%), Gaps = 12/80 (15%) Query: 42 GFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGP-GMCGPANW 100 G L P GP SG G PG P + P G G P PGP G GPA Sbjct: 284 GAAGLPGPQGP----SGAKGEPGTRGPPGLIGPTGYG-------MPGLPGPKGDRGPAGV 332 Query: 101 GYVLGGRGRGPDEYEKRYSG 120 +LG RG ++ E G Sbjct: 333 PGLLGDRGEPGEDGEPGEQG 352 Score = 30.0 bits (66), Expect = 7.1 Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 49 PDGPASPTSGPVGRPGGVSGPSWLQPPG-TGAAQSPRKAPRRPGPGMCGPANWGYVLGGR 107 P P +P G P G+ GP+ L PG G +P PG+ GP +G + Sbjct: 213 PGLPGAPGQGGAPGPPGLPGPAGLGKPGLDGLPGAPGDKGESGPPGVPGPRGEPGAVGPK 272 Query: 108 G 108 G Sbjct: 273 G 273 >gi|33286446 opioid growth factor receptor [Homo sapiens] Length = 677 Score = 34.7 bits (78), Expect = 0.29 Identities = 19/49 (38%), Positives = 22/49 (44%), Gaps = 3/49 (6%) Query: 50 DGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98 +G P G G P GPS P G A+SP + PGP GPA Sbjct: 505 EGRTGPKEGTPGSPSETPGPSPAGPAGDEPAESPSET---PGPRPAGPA 550 Score = 30.8 bits (68), Expect = 4.1 Identities = 20/51 (39%), Positives = 22/51 (43%), Gaps = 5/51 (9%) Query: 48 SPDGPASPTSGPVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98 SP GPA P P GP P G A+SP + PGP GPA Sbjct: 525 SPAGPAGDE--PAESPSETPGPRPAGPAGDEPAESPSET---PGPRPAGPA 570 Score = 30.0 bits (66), Expect = 7.1 Identities = 19/48 (39%), Positives = 21/48 (43%), Gaps = 4/48 (8%) Query: 52 PASPTSG-PVGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPGMCGPA 98 PA PT P P GP P G A+SP + PGP GPA Sbjct: 586 PAGPTRDEPAESPSETPGPRPAGPAGDEPAESPSET---PGPRPAGPA 630 >gi|118498339 EMI domain containing 2 [Homo sapiens] Length = 439 Score = 34.7 bits (78), Expect = 0.29 Identities = 33/104 (31%), Positives = 37/104 (35%), Gaps = 25/104 (24%) Query: 38 PLSFGFQRLRSPDGPASPTS-----GPVGRPG-----------GVSGP-SWLQPPGTGAA 80 PL+ R R P GPA P GP G PG G +GP L PPG Sbjct: 184 PLAHPVPRQRRPTGPAGPPGQTGPPGPAGPPGSKGDRGQTGEKGPAGPPGLLGPPGPRGL 243 Query: 81 QSPRKAPRRPGPGMCGPANWGYVLGGRGRGPDEYEKRYSGAFPP 124 P PGP GPA G G P+ + PP Sbjct: 244 PGEMGRPGPPGPP--GPA------GNPGPSPNSPQGALYSLQPP 279 >gi|239754674 PREDICTED: hypothetical protein [Homo sapiens] Length = 480 Score = 34.3 bits (77), Expect = 0.37 Identities = 25/79 (31%), Positives = 36/79 (45%), Gaps = 9/79 (11%) Query: 40 SFGFQRLRSPDGPASPTSGPVGRPGGVSGPSWLQPPG--TGAAQSPR------KAPRRPG 91 SFG + P P T+ P +PG + P+ ++ PG GA++ PR + P PG Sbjct: 189 SFGGRPKSQPPLPQE-TAAPAPQPGPTAPPARVREPGRAEGASREPRLRSRAARPPPAPG 247 Query: 92 PGMCGPANWGYVLGGRGRG 110 PG A+ G G G Sbjct: 248 PGALSRASRSRAAGRPGPG 266 >gi|18105032 type X collagen alpha 1 precursor [Homo sapiens] Length = 680 Score = 34.3 bits (77), Expect = 0.37 Identities = 28/67 (41%), Positives = 30/67 (44%), Gaps = 12/67 (17%) Query: 42 GFQRLRSPDGPASPT-----SGPVGRPG----GVSG-PSWLQPPGTGAAQSPRKAPRRPG 91 G Q P GPA P SGP G+PG G+ G P PPG A P P PG Sbjct: 57 GEQGTPGPPGPAGPRGHPGPSGPPGKPGYGSPGLQGEPGLPGPPGPSAVGKP-GVPGLPG 115 Query: 92 -PGMCGP 97 PG GP Sbjct: 116 KPGERGP 122 Score = 32.7 bits (73), Expect = 1.1 Identities = 36/111 (32%), Positives = 39/111 (35%), Gaps = 20/111 (18%) Query: 16 GLHGVLWLVFGLGPSMGFYQRFPLSFGFQRLRSPDGPASPTSGPVGRPG--------GVS 67 GL G L GPS P G R P GP GP G PG G+ Sbjct: 89 GLQGEPGLPGPPGPSAVGKPGVPGLPGKPGERGPYGPKGDV-GPAGLPGPRGPPGPPGIP 147 Query: 68 GPSWLQPPGTGAAQSPRKAPRRPG----------PGMCG-PANWGYVLGGR 107 GP+ + PG Q P AP G PGM G GY GR Sbjct: 148 GPAGISVPGKPGQQGPTGAPGPRGFPGEKGAPGVPGMNGQKGEMGYGAPGR 198 Score = 32.3 bits (72), Expect = 1.4 Identities = 27/82 (32%), Positives = 32/82 (39%), Gaps = 19/82 (23%) Query: 58 GPVGRPG-----GVSGPSWLQ-------PPGTGAAQSPRKAPRR---PGP----GMCGPA 98 GP G PG G GP+ L PPG Q P+ P PGP G GPA Sbjct: 311 GPAGLPGGPGAKGEQGPAGLPGKPGLTGPPGNMGPQGPKGIPGSHGLPGPKGETGPAGPA 370 Query: 99 NWGYVLGGRGRGPDEYEKRYSG 120 + G RG + + Y G Sbjct: 371 GYPGAKGERGSPGSDGKPGYPG 392 >gi|38373671 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 34.3 bits (77), Expect = 0.37 Identities = 33/95 (34%), Positives = 37/95 (38%), Gaps = 17/95 (17%) Query: 38 PLSFGFQRLRSPDGPASPTS---GP-VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93 P + G RL S GP P GP V +P VS P PPGT P P P Sbjct: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT-----QMTGPLGPLPP 269 Query: 94 MCGPANWGYV-----LGGRGRGPDEYEKRYSGAFP 123 M P GY G RGP + Y G +P Sbjct: 270 MHSPQQPGYQPQQNGSFGPARGP---QSNYGGPYP 301 >gi|38373669 SEC24-related protein C [Homo sapiens] Length = 1094 Score = 34.3 bits (77), Expect = 0.37 Identities = 33/95 (34%), Positives = 37/95 (38%), Gaps = 17/95 (17%) Query: 38 PLSFGFQRLRSPDGPASPTS---GP-VGRPGGVSGPSWLQPPGTGAAQSPRKAPRRPGPG 93 P + G RL S GP P GP V +P VS P PPGT P P P Sbjct: 215 PPASGGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGT-----QMTGPLGPLPP 269 Query: 94 MCGPANWGYV-----LGGRGRGPDEYEKRYSGAFP 123 M P GY G RGP + Y G +P Sbjct: 270 MHSPQQPGYQPQQNGSFGPARGP---QSNYGGPYP 301 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.140 0.434 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,537,105 Number of Sequences: 37866 Number of extensions: 1557457 Number of successful extensions: 6867 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 28 Number of HSP's successfully gapped in prelim test: 207 Number of HSP's that attempted gapping in prelim test: 5922 Number of HSP's gapped (non-prelim): 1053 length of query: 657 length of database: 18,247,518 effective HSP length: 109 effective length of query: 548 effective length of database: 14,120,124 effective search space: 7737827952 effective search space used: 7737827952 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.