Guide to the Human Genome
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Name: EDEM1 Sequence: fasta or formatted (657aa) NCBI GI: 7662002
Description:

ER degradation enhancer, mannosidase alpha-like 1

Referenced in:

Protein Glycosylation

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         36           2
 C cysteine            1.2          8           1
 D aspartate           5.5         36           1
 E glutamate           5.2         34           2
 F phenylalanine       4.7         31           2
 G glycine             9.6         63           2
 H histidine           2.3         15           2
 I isoleucine          3.7         24           2
 K lysine              4.0         26           1
 L leucine            11.6         76           2
 M methionine          2.6         17           1
 N asparagine          4.6         30           2
 P proline             6.4         42           2
 Q glutamine           4.0         26           1
 R arginine            6.1         40           2
 S serine              6.4         42           3
 T threonine           4.3         28           2
 V valine              6.2         41           2
 W tryptophan          1.7         11           1
 Y tyrosine            4.7         31           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   ER degradation enhancer, mannosidase alpha-like 1 [Ho... 
EDEM3                 0.269   ER degradation enhancer, mannosidase alpha-like 3 [...
EDEM2                 0.248   ER degradation enhancer, mannosidase alpha-like 2 i...
EDEM2                 0.227   ER degradation enhancer, mannosidase alpha-like 2 i...
MAN1B1                0.122   alpha 1,2-mannosidase 
MAN1A2                0.113   mannosidase, alpha, class 1A, member 2 
MAN1A1                0.104   mannosidase, alpha, class 1A, member 1 
MAN1C1                0.099   mannosidase, alpha, class 1C, member 1 
PPP1R10               0.015   protein phosphatase 1, regulatory subunit 10 
COL2A1                0.011   collagen, type II, alpha 1 isoform 1 precursor [Hom...
COL2A1                0.011   collagen, type II, alpha 1 isoform 2 precursor [Hom...
COL9A3                0.010   alpha 3 type IX collagen 
COL15A1               0.009   alpha 1 type XV collagen precursor 
LOC100290372          0.009   PREDICTED: hypothetical protein XP_002346788 
LOC100288606          0.009   PREDICTED: hypothetical protein XP_002342652 
COL5A1                0.009   alpha 1 type V collagen preproprotein 
COL7A1                0.009   alpha 1 type VII collagen precursor 
COL1A1                0.008   alpha 1 type I collagen preproprotein 
COL3A1                0.008   collagen type III alpha 1 preproprotein 
COL1A2                0.008   alpha 2 type I collagen 
COL11A2               0.008   collagen, type XI, alpha 2 isoform 2 preproprotein ...
COL11A2               0.008   collagen, type XI, alpha 2 isoform 3 preproprotein ...
COL11A2               0.008   collagen, type XI, alpha 2 isoform 1 preproprotein ...
COL8A2                0.008   collagen, type VIII, alpha 2 
OGFR                  0.008   opioid growth factor receptor 
EMID2                 0.008   EMI domain containing 2 
LOC100127891          0.007   PREDICTED: hypothetical protein 
COL10A1               0.007   type X collagen alpha 1 precursor 
SEC24C                0.007   SEC24-related protein C 
SEC24C                0.007   SEC24-related protein C 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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