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Search of human proteins with 7657599
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7657599 sorting nexin 5 [Homo sapiens]
(404 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|23111047 sorting nexin 5 [Homo sapiens] 797 0.0
gi|7657599 sorting nexin 5 [Homo sapiens] 797 0.0
gi|88703041 sorting nexin 6 isoform b [Homo sapiens] 536 e-152
gi|72534838 sorting nexin 6B [Homo sapiens] 505 e-143
gi|88703043 sorting nexin 6 isoform a [Homo sapiens] 386 e-107
gi|23111038 sorting nexin 2 [Homo sapiens] 107 3e-23
gi|23111034 sorting nexin 1 isoform a [Homo sapiens] 98 2e-20
gi|23111032 sorting nexin 1 isoform b [Homo sapiens] 96 4e-20
gi|23111036 sorting nexin 1 isoform c [Homo sapiens] 88 1e-17
gi|153791707 sorting nexin family member 30 [Homo sapiens] 66 5e-11
gi|194294540 sorting nexin 7 isoform a [Homo sapiens] 58 1e-08
gi|23111055 sorting nexin 7 isoform b [Homo sapiens] 57 4e-08
gi|23111030 sorting nexin 12 [Homo sapiens] 47 3e-05
gi|4507143 sorting nexin 3 isoform a [Homo sapiens] 44 3e-04
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 40 0.004
gi|197927454 DEK oncogene isoform 2 [Homo sapiens] 39 0.011
gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 38 0.019
gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 38 0.019
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 37 0.032
gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens] 37 0.032
gi|23397574 sorting nexin 33 [Homo sapiens] 37 0.032
gi|21536423 amphiphysin isoform 2 [Homo sapiens] 35 0.093
gi|4502081 amphiphysin isoform 1 [Homo sapiens] 35 0.093
gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1 ... 35 0.093
gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1 ... 35 0.093
gi|169169660 PREDICTED: hypothetical protein [Homo sapiens] 35 0.16
gi|169169929 PREDICTED: hypothetical protein [Homo sapiens] 35 0.16
gi|56961680 coiled-coil domain containing 147 [Homo sapiens] 34 0.21
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 34 0.27
gi|122937396 coiled-coil domain containing 150 [Homo sapiens] 34 0.27
>gi|23111047 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 797 bits (2058), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS 60
MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
Sbjct: 1 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS 60
Query: 61 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE 120
PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
Sbjct: 61 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE 120
Query: 121 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK 180
FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
Sbjct: 121 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK 180
Query: 181 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV 240
EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
Sbjct: 181 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV 240
Query: 241 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML 300
ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
Sbjct: 241 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML 300
Query: 301 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE 360
NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
Sbjct: 301 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE 360
Query: 361 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN 404
LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
Sbjct: 361 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN 404
>gi|7657599 sorting nexin 5 [Homo sapiens]
Length = 404
Score = 797 bits (2058), Expect = 0.0
Identities = 404/404 (100%), Positives = 404/404 (100%)
Query: 1 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS 60
MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
Sbjct: 1 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS 60
Query: 61 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE 120
PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
Sbjct: 61 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE 120
Query: 121 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK 180
FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
Sbjct: 121 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK 180
Query: 181 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV 240
EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
Sbjct: 181 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV 240
Query: 241 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML 300
ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
Sbjct: 241 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML 300
Query: 301 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE 360
NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
Sbjct: 301 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE 360
Query: 361 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN 404
LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
Sbjct: 361 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN 404
>gi|88703041 sorting nexin 6 isoform b [Homo sapiens]
Length = 418
Score = 536 bits (1382), Expect = e-152
Identities = 256/387 (66%), Positives = 326/387 (84%), Gaps = 1/387 (0%)
Query: 12 EEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHED 71
EEDR L++++VDL D +LQ+DI DALSERDKVKFTVHTK++LP F+ EFSV RQHE+
Sbjct: 26 EEDRG-LKAINVDLQSDAALQVDISDALSERDKVKFTVHTKSSLPNFKQNEFSVVRQHEE 84
Query: 72 FVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAE 131
F+WLHD+ +E DYAG IIPPAP +PDFD REK+QKLGEGEGSMTKEEF KMKQELEAE
Sbjct: 85 FIWLHDSFVENEDYAGYIIPPAPPRPDFDASREKLQKLGEGEGSMTKEEFTKMKQELEAE 144
Query: 132 YLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVV 191
YLA+FKKTV+ HEVFL R+++HP+L +D NFHVFLEY+QDLSVR KN KE FFK++V
Sbjct: 145 YLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMV 204
Query: 192 KSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACL 251
KSAD V+ +GVK+VDDFFE E+ FL+ Y+NR+KD+ K+D+MTRSHK+ ADDY + L
Sbjct: 205 KSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSL 264
Query: 252 HSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYR 311
++L ++ T I K+ LKV+ELF+K RK+E RVS+DEDLKL++LL+YY+ +AAKDLLYR
Sbjct: 265 YALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYR 324
Query: 312 RTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAA 371
R+++L+DYEN+NKALDKAR K+KDV AE QQ CCQKFE++SESAK+ELI+FK +RVAA
Sbjct: 325 RSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAA 384
Query: 372 FRKNLIEMSELEIKHARNNVSLLQSCI 398
FRKNL+E++ELE+KHA+ N+ LLQ+C+
Sbjct: 385 FRKNLVELAELELKHAKGNLQLLQNCL 411
>gi|72534838 sorting nexin 6B [Homo sapiens]
Length = 403
Score = 505 bits (1301), Expect = e-143
Identities = 243/384 (63%), Positives = 317/384 (82%), Gaps = 3/384 (0%)
Query: 22 SVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIE 81
SVDL D SLQ++I DA+SERDKVKFTV TK+ LP F EFSV RQHE+F+WLHD +E
Sbjct: 17 SVDLQGDSSLQVEISDAVSERDKVKFTVQTKSCLPHFAQTEFSVVRQHEEFIWLHDAYVE 76
Query: 82 TTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVS 141
+YAGLIIPPAP +PDF+ REK+QKLGEG+ S+T+EEFAKMKQELEAEYLA+FKKTV+
Sbjct: 77 NEEYAGLIIPPAPPRPDFEASREKLQKLGEGDSSVTREEFAKMKQELEAEYLAIFKKTVA 136
Query: 142 SHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFT- 200
HEVFLQRL++HP L +D NF VFLEY QDLSVR KN KE+ GGF +++VKSADE L T
Sbjct: 137 MHEVFLQRLAAHPTLRRDHNFFVFLEYGQDLSVRGKNRKELLGGFLRNIVKSADEALITG 196
Query: 201 --GVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEE 258
G+KEVDDFFE E+ FL+ Y+ RI+D+C++AD++ R+HK +ADDYI +A L SL +E
Sbjct: 197 MSGLKEVDDFFEHERTFLLEYHTRIRDACLRADRVMRAHKCLADDYIPISAALSSLGTQE 256
Query: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318
++ LK+AELFE+LRK+EGRV+SDEDLKL+++LRYYM + +AAKDLLYRR +AL D
Sbjct: 257 VNQLRTSFLKLAELFERLRKLEGRVASDEDLKLSDMLRYYMRDSQAAKDLLYRRLRALAD 316
Query: 319 YENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIE 378
YEN+NKALDKAR ++++V+ AE+HQQ CCQ+FE+LS+SAK+EL++FK +RV++FRKNLIE
Sbjct: 317 YENANKALDKARTRNREVRPAESHQQLCCQRFERLSDSAKQELMDFKSRRVSSFRKNLIE 376
Query: 379 MSELEIKHARNNVSLLQSCIDLFK 402
++ELE+KHA+ + +L++ + K
Sbjct: 377 LAELELKHAKASTLILRNTLVALK 400
>gi|88703043 sorting nexin 6 isoform a [Homo sapiens]
Length = 290
Score = 386 bits (991), Expect = e-107
Identities = 184/283 (65%), Positives = 239/283 (84%)
Query: 116 MTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVR 175
MTKEEF KMKQELEAEYLA+FKKTV+ HEVFL R+++HP+L +D NFHVFLEY+QDLSVR
Sbjct: 1 MTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHVFLEYNQDLSVR 60
Query: 176 RKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTR 235
KN KE FFK++VKSAD V+ +GVK+VDDFFE E+ FL+ Y+NR+KD+ K+D+MTR
Sbjct: 61 GKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVKDASAKSDRMTR 120
Query: 236 SHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELL 295
SHK+ ADDY + L++L ++ T I K+ LKV+ELF+K RK+E RVS+DEDLKL++LL
Sbjct: 121 SHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVSADEDLKLSDLL 180
Query: 296 RYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSE 355
+YY+ +AAKDLLYRR+++L+DYEN+NKALDKAR K+KDV AE QQ CCQKFE++SE
Sbjct: 181 KYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQLCCQKFEKISE 240
Query: 356 SAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCI 398
SAK+ELI+FK +RVAAFRKNL+E++ELE+KHA+ N+ LLQ+C+
Sbjct: 241 SAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCL 283
>gi|23111038 sorting nexin 2 [Homo sapiens]
Length = 519
Score = 107 bits (266), Expect = 3e-23
Identities = 101/379 (26%), Positives = 175/379 (46%), Gaps = 55/379 (14%)
Query: 34 DIPDALSERDKV--------KFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDY 85
DI +S+ +KV + V TKT+L F EFSV R+ DF+ LH L +
Sbjct: 141 DIEIGVSDPEKVGDGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLH 200
Query: 86 AGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEV 145
G I+PPAP K M K+ G+ + EF + ++ ++ E
Sbjct: 201 VGYIVPPAPEKSIVG-----MTKVKVGKEDSSSTEFVEKRR--------------AALER 241
Query: 146 FLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFG-GFFKSVVKSADEVLFTGVK- 203
+LQR HP L +D + FLE + R NT+ + G G + V K+AD V +K
Sbjct: 242 YLQRTVKHPTLLQDPDLRQFLESSE--LPRAVNTQALSGAGILRMVNKAADAVNKMTIKM 299
Query: 204 -EVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL----EE 258
E D +FE+++ N +++ V + + K ++ +TAA S A+ E+
Sbjct: 300 NESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELS---ANTAAFAKSAAMLGNSED 356
Query: 259 PTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALID 318
T + + L ++AE+ EK+ ++ + + +ELL Y+ I A K + R K
Sbjct: 357 HTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQK 416
Query: 319 YENSNKAL----------------DKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELI 362
+E++ L DK + +++ EA Q+ + FEQ+S++ ++E+
Sbjct: 417 WEDAQITLLKKREAEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVG 476
Query: 363 NFKRKRVAAFRKNLIEMSE 381
F+++RV F+ +I+ E
Sbjct: 477 RFEKERVKDFKTVIIKYLE 495
>gi|23111034 sorting nexin 1 isoform a [Homo sapiens]
Length = 522
Score = 97.8 bits (242), Expect = 2e-20
Identities = 100/399 (25%), Positives = 188/399 (47%), Gaps = 56/399 (14%)
Query: 6 ELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSV 65
EL ++++ED+ DL V + I D ++ V + V T+T+LP F+S +F+V
Sbjct: 133 ELEEEEQEDQ-------FDLTVGITDPEKIGDGMNAY--VAYKVTTQTSLPLFRSKQFAV 183
Query: 66 TRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMK 125
R+ DF+ L++ L E G I+PP P K MTK + K +
Sbjct: 184 KRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLI---------------GMTKVKVGK-E 227
Query: 126 QELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFG- 184
AE+L +K ++ E +LQR+ +HP + +D + FLE ++ R T+ + G
Sbjct: 228 DSSSAEFL---EKRRAALERYLQRIVNHPTMLQDPDVREFLEKEE--LPRAVGTQTLSGA 282
Query: 185 GFFKSVVKSADEVLFTGVK--EVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVAD 242
G K K+ D V +K E D +FE++ + R++ + + K +A
Sbjct: 283 GLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELA- 341
Query: 243 DYIHTAACLHSLAL----EEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYY 298
++TA SLA+ E+ T + + L ++AE+ EK+ ++ ++++ L ELL Y
Sbjct: 342 --LNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY 399
Query: 299 MLNIEAAKDLLYRRTKALIDYENSNKALDKAR-------LKSKDVKLAEAHQQ------- 344
+ + + +R K ++++ L K R +K KL +A +
Sbjct: 400 IRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEILEWESR 459
Query: 345 --ECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSE 381
+ + FE++S ++E+I F++++ F+ ++I+ E
Sbjct: 460 VTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 498
>gi|23111032 sorting nexin 1 isoform b [Homo sapiens]
Length = 457
Score = 96.3 bits (238), Expect = 4e-20
Identities = 91/360 (25%), Positives = 171/360 (47%), Gaps = 47/360 (13%)
Query: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
V + V T+T+LP F+S +F+V R+ DF+ L++ L E G I+PP P K
Sbjct: 98 VAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLI----- 152
Query: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
MTK + K + AE+L +K ++ E +LQR+ +HP + +D +
Sbjct: 153 ----------GMTKVKVGK-EDSSSAEFL---EKRRAALERYLQRIVNHPTMLQDPDVRE 198
Query: 165 FLEYDQDLSVRRKNTKEMFG-GFFKSVVKSADEVLFTGVK--EVDDFFEQEKNFLINYYN 221
FLE ++ R T+ + G G K K+ D V +K E D +FE++ +
Sbjct: 199 FLEKEE--LPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQ 256
Query: 222 RIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL----EEPTVIKKYLLKVAELFEKLR 277
R++ + + K +A ++TA SLA+ E+ T + + L ++AE+ EK+
Sbjct: 257 RLRKLHAVVETLVNHRKELA---LNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIE 313
Query: 278 KVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKAR------- 330
++ ++++ L ELL Y+ + + +R K ++++ L K R
Sbjct: 314 QLHQEQANNDFFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLL 373
Query: 331 LKSKDVKLAEAHQQ---------ECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSE 381
+K KL +A + + + FE++S ++E+I F++++ F+ ++I+ E
Sbjct: 374 WANKPDKLQQAKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLE 433
>gi|23111036 sorting nexin 1 isoform c [Homo sapiens]
Length = 474
Score = 88.2 bits (217), Expect = 1e-17
Identities = 96/383 (25%), Positives = 177/383 (46%), Gaps = 72/383 (18%)
Query: 6 ELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSV 65
EL ++++ED+ DL V + I D ++ V + V T+T+LP F+S +F+V
Sbjct: 133 ELEEEEQEDQ-------FDLTVGITDPEKIGDGMNAY--VAYKVTTQTSLPLFRSKQFAV 183
Query: 66 TRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMK 125
R+ DF+ L++ L E G I+PP P K MTK + K +
Sbjct: 184 KRRFSDFLGLYEKLSEKHSQNGFIVPPPPEKSLI---------------GMTKVKVGK-E 227
Query: 126 QELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFG- 184
AE+L +K ++ E +LQR+ +HP + +D + FLE ++ R T+ + G
Sbjct: 228 DSSSAEFL---EKRRAALERYLQRIVNHPTMLQDPDVREFLEKEE--LPRAVGTQTLSGA 282
Query: 185 GFFKSVVKSADEVLFTGVK--EVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVAD 242
G K K+ D V +K E D +FE++ + R++ + + K +A
Sbjct: 283 GLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETLVNHRKELA- 341
Query: 243 DYIHTAACLHSLAL----EEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYY 298
++TA SLA+ E+ T + + L ++AE+ EK+ ++ ++++ L ELL Y
Sbjct: 342 --LNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLAELLSDY 399
Query: 299 MLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAK 358
+ R A++ +E + Q E + FE++S +
Sbjct: 400 I------------RLLAIVRWE------------------SRVTQYE--RDFERISTVVR 427
Query: 359 EELINFKRKRVAAFRKNLIEMSE 381
+E+I F++++ F+ ++I+ E
Sbjct: 428 KEVIRFEKEKSKDFKNHVIKYLE 450
>gi|153791707 sorting nexin family member 30 [Homo sapiens]
Length = 437
Score = 66.2 bits (160), Expect = 5e-11
Identities = 78/369 (21%), Positives = 153/369 (41%), Gaps = 57/369 (15%)
Query: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
+ + + TK+T F PE+SV R+++DF WL L E+ +IPP P K G +
Sbjct: 109 ITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTH--LIPPLPEKFVVKGVVD 166
Query: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
+ EEF + +++ + + FL+R++ HPVLS + +F++
Sbjct: 167 RF-----------SEEFVETRRK--------------ALDKFLKRITDHPVLSFNEHFNI 201
Query: 165 FLEYDQDLSVRRK-----------NTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEK 213
FL +DL+ +K + K + GG +K + + F + + D F +
Sbjct: 202 FLT-AKDLNAYKKQGIALLTRMGESVKHVTGG-YKLRTRPLE---FAAIGDYLDTFALK- 255
Query: 214 NFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELF 273
+ +RI +K + T + L E + + +
Sbjct: 256 ---LGTIDRIAQRIIKEEIEYLVELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTAL 312
Query: 274 EKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKS 333
E+L + D +LR Y+L ++ K +L +R + +YE L+ L+
Sbjct: 313 EEL-------TDDMTEDFLPVLREYILYSDSMKSVLKKRDQVQAEYE---AKLEAVALRK 362
Query: 334 KDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSL 393
+D A ++C + E + K ++ ++ + FR+ L+ M++ I++ +
Sbjct: 363 EDRPKVPADVEKCQDRMECFNADLKADMERWQNNKRQDFRQLLMGMADKNIQYYEKCLMA 422
Query: 394 LQSCIDLFK 402
+S I L +
Sbjct: 423 WESIIPLLQ 431
>gi|194294540 sorting nexin 7 isoform a [Homo sapiens]
Length = 451
Score = 58.2 bits (139), Expect = 1e-08
Identities = 74/343 (21%), Positives = 137/343 (39%), Gaps = 34/343 (9%)
Query: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
+ + + TKT+ F S EF V R+++DF+WL L E + LIIPP P K G E
Sbjct: 114 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVE 171
Query: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
+ ++F +E A+ K FL R++ HP L+ + +F +
Sbjct: 172 RF-----------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKI 206
Query: 165 FLEYDQ-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRI 223
FL +LS +K + ++V A + GVK + F + NF+ + +I
Sbjct: 207 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKI 264
Query: 224 KDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRV 283
+ ++ + + D+ + +H L + L VA ++ K +
Sbjct: 265 NLIDKISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 323
Query: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQ 343
S L ++ Y+L E ++ RR + + ++ + L K D L
Sbjct: 324 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL---TYKKADTDLLPEEI 380
Query: 344 QECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKH 386
+ K E + + K + +K+ + +M+E I +
Sbjct: 381 GKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHY 423
>gi|23111055 sorting nexin 7 isoform b [Homo sapiens]
Length = 336
Score = 56.6 bits (135), Expect = 4e-08
Identities = 64/283 (22%), Positives = 117/283 (41%), Gaps = 31/283 (10%)
Query: 45 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE 104
+ + + TKT+ F S EF V R+++DF+WL L E + LIIPP P K G E
Sbjct: 50 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVE 107
Query: 105 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV 164
+ ++F +E A+ K FL R++ HP L+ + +F +
Sbjct: 108 RF-----------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKI 142
Query: 165 FLEYDQ-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRI 223
FL +LS +K + ++V A + GVK + F + NF+ + +I
Sbjct: 143 FLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKI 200
Query: 224 KDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRV 283
+ ++ + + D+ + +H L + L VA ++ K +
Sbjct: 201 NLIDKISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKR 259
Query: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKAL 326
S L ++ Y+L E ++ RR + + ++ + L
Sbjct: 260 MSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL 302
>gi|23111030 sorting nexin 12 [Homo sapiens]
Length = 162
Score = 47.0 bits (110), Expect = 3e-05
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 23/121 (19%)
Query: 47 FTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKM 106
+ V +T LP F+ E V R++ DF WL + L + +++PP P G K
Sbjct: 50 YEVRMRTNLPIFKLKESCVRRRYSDFEWLKNELERDSK---IVVPPLP------GKALKR 100
Query: 107 QKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFL 166
Q G+ + +E F + +++ E F+ +++ HP+ +R H+FL
Sbjct: 101 QLPFRGDEGIFEESFIEERRQ--------------GLEQFINKIAGHPLAQNERCLHMFL 146
Query: 167 E 167
+
Sbjct: 147 Q 147
>gi|4507143 sorting nexin 3 isoform a [Homo sapiens]
Length = 162
Score = 43.9 bits (102), Expect = 3e-04
Identities = 28/121 (23%), Positives = 53/121 (43%), Gaps = 23/121 (19%)
Query: 47 FTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKM 106
+ + KT LP F+ E +V R++ DF WL L + +++PP P G
Sbjct: 49 YEIRVKTNLPIFKLKESTVRRRYSDFEWLRSELERESK---VVVPPLP------GKAFLR 99
Query: 107 QKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFL 166
Q G+ + + F + +++ E F+ +++ HP+ +R H+FL
Sbjct: 100 QLPFRGDDGIFDDNFIEERKQ--------------GLEQFINKVAGHPLAQNERCLHMFL 145
Query: 167 E 167
+
Sbjct: 146 Q 146
>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
Length = 2230
Score = 40.0 bits (92), Expect = 0.004
Identities = 89/403 (22%), Positives = 165/403 (40%), Gaps = 55/403 (13%)
Query: 4 VPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEF 63
V +L+QQ E+ S++ L + + D E+++ K + K + Q E
Sbjct: 863 VQDLMQQLEKQNSEMEQKVKSLT--QVYESKLEDGNKEQEQTKQILVEKENM-ILQMRE- 918
Query: 64 SVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTK----- 118
Q ++ L L D ++ TK F +KM+K+ + M +
Sbjct: 919 ---GQKKEIEILTQKLSAKEDSIHILNEEYETK--FKNQEKKMEKVKQKAKEMQETLKKK 973
Query: 119 --EEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLS--- 173
++ AK+K+ELE L + +K + L+ ++ D + + +
Sbjct: 974 LLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQKEQIESLT 1033
Query: 174 -VRRKNTKEMFGGFFKSVVKSADEV-------LFTGVKEVDDF------FEQEKNFLINY 219
V R+ ++ + K + + A+E+ L +EV + F EK +
Sbjct: 1034 EVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKE 1093
Query: 220 YNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKV-AELFEKLRK 278
+K+ VK D + + +A ++SLA +E T +K +L K+ +L + L++
Sbjct: 1094 ITWLKEEGVKQDTTLNE---LQEQLKQKSAHVNSLAQDE-TKLKAHLEKLEVDLNKSLKE 1149
Query: 279 --------VEGRVSSDEDL-KLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKA 329
VE ++ ++ED K++EL E + L +E SNK+L+
Sbjct: 1150 NTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKS-------SHEKSNKSLEDK 1202
Query: 330 RLKSKDVKLAEAHQQE-CCQKFEQLSESAKEELINFKRKRVAA 371
L+ K + A Q + CC+K E L E+ ELIN + A
Sbjct: 1203 SLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNA 1245
>gi|197927454 DEK oncogene isoform 2 [Homo sapiens]
Length = 341
Score = 38.5 bits (88), Expect = 0.011
Identities = 79/332 (23%), Positives = 129/332 (38%), Gaps = 48/332 (14%)
Query: 91 PPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQ----ELEAEYLAVFKKTVSSHEVF 146
P + +P+ GPRE+ ++ E E +EE K K E+E + + KK
Sbjct: 17 PASEKEPEMPGPREESEE-EEDEDDEEEEEEEKGKGQKLCEIERIHFFLSKKKTDELRNL 75
Query: 147 LQRLSSHP--VLSKDRNFHVFLEYD-QDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVK 203
+ L + P V S +N F + + SV+ K +EM F +++KS EVL
Sbjct: 76 HKLLYNRPGTVSSLKKNVGQFSGFPFEKGSVQYKKKEEMLKKFRNAMLKSICEVLDLERS 135
Query: 204 EVD-DFFEQEKNFLIN------YYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL 256
V+ + ++ NFL++ + K +C K K R+ +A T C L+
Sbjct: 136 GVNSELVKRILNFLMHPKPSGKPLPKSKKTCSKGSKKERNSSGMARKAKRT-KCPEILSD 194
Query: 257 EEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKAL 316
E ++ EK K E S DED + E E K R
Sbjct: 195 ESS----------SDEDEKKNKEES--SDDEDKESEE---------EPPKKTAKREKPKQ 233
Query: 317 IDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRK-----RVAA 371
S K++ A +K D + +Q ++ E S E LI +K +
Sbjct: 234 KATSKSKKSVKSANVKKADSSTTKKNQNSSKKESESEDSSDDEPLIKKLKKPPTDEELKE 293
Query: 372 FRKNLIEMSELEIKHARNNVSLLQSCIDLFKN 403
K L+ + LE V++ Q C +++N
Sbjct: 294 TIKKLLASANLE------EVTMKQICKKVYEN 319
>gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo
sapiens]
Length = 1591
Score = 37.7 bits (86), Expect = 0.019
Identities = 77/412 (18%), Positives = 175/412 (42%), Gaps = 46/412 (11%)
Query: 7 LLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERD-KVKFTVHTKTTLPTFQSPEFSV 65
L+++ EE+ +K++ + +L + + + L +D + H K + Q+ +
Sbjct: 881 LIKETEENENKIKKLKGEL-------VCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQK 933
Query: 66 TRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMK 125
+ E+ + + I+ + I+ K + EK+Q L S+ + +++
Sbjct: 934 LLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQSLEQSHLKELE 992
Query: 126 QELEAEYLAVFKKTVSSHEVFLQRL--SSHPVLSKDRNFH--VFLEYDQDLSVRRKNTKE 181
L+ ++ F+K ++ H V L+ L + ++++ + H + E ++ L + +
Sbjct: 993 DTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSD 1052
Query: 182 MFGGFFKSVVKSADEVLFTGVKEV--DDFFEQEKNFLINYYNRIKDSC-VKADKMTRSHK 238
+ K V+ A + T ++ ++ Q+K L + + ++ + K+ + +
Sbjct: 1053 LSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQ 1112
Query: 239 NVADDY------------IHTAACLHSLAL---EEPTVIKKYLLKVAELFEKLRKVEGRV 283
+ ++Y I C+ L EE ++K L KV L + ++E +
Sbjct: 1113 DNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNL 1172
Query: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLK---SKDVKLAE 340
++ ++L L + +E KD + T+ YE + L+K R K S++ +
Sbjct: 1173 -KEQIIELQSKLDSELSALERQKD--EKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQ 1229
Query: 341 AHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVS 392
Q+ C+K E + + KE FK +R K L+E ++KH N ++
Sbjct: 1230 LIQKLNCEKDEAIQTALKE----FKLER-EVVEKELLE----KVKHLENQIA 1272
>gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo
sapiens]
Length = 1594
Score = 37.7 bits (86), Expect = 0.019
Identities = 77/412 (18%), Positives = 175/412 (42%), Gaps = 46/412 (11%)
Query: 7 LLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERD-KVKFTVHTKTTLPTFQSPEFSV 65
L+++ EE+ +K++ + +L + + + L +D + H K + Q+ +
Sbjct: 881 LIKETEENENKIKKLKGEL-------VCLEEVLQNKDNEFALVKHEKEAVICLQNEKDQK 933
Query: 66 TRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMK 125
+ E+ + + I+ + I+ K + EK+Q L S+ + +++
Sbjct: 934 LLEMENIMHSQNCEIKELKQSREIVLEDLKKLHVEND-EKLQLLRAELQSLEQSHLKELE 992
Query: 126 QELEAEYLAVFKKTVSSHEVFLQRL--SSHPVLSKDRNFH--VFLEYDQDLSVRRKNTKE 181
L+ ++ F+K ++ H V L+ L + ++++ + H + E ++ L + +
Sbjct: 993 DTLQVRHIQEFEKVMTDHRVSLEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSD 1052
Query: 182 MFGGFFKSVVKSADEVLFTGVKEV--DDFFEQEKNFLINYYNRIKDSC-VKADKMTRSHK 238
+ K V+ A + T ++ ++ Q+K L + + ++ + K+ + +
Sbjct: 1053 LSDTRCKLEVELALKEAETDEIKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQ 1112
Query: 239 NVADDY------------IHTAACLHSLAL---EEPTVIKKYLLKVAELFEKLRKVEGRV 283
+ ++Y I C+ L EE ++K L KV L + ++E +
Sbjct: 1113 DNNENYQVGLAELRTLMTIEKDQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNL 1172
Query: 284 SSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLK---SKDVKLAE 340
++ ++L L + +E KD + T+ YE + L+K R K S++ +
Sbjct: 1173 -KEQIIELQSKLDSELSALERQKD--EKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQ 1229
Query: 341 AHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVS 392
Q+ C+K E + + KE FK +R K L+E ++KH N ++
Sbjct: 1230 LIQKLNCEKDEAIQTALKE----FKLER-EVVEKELLE----KVKHLENQIA 1272
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 37.0 bits (84), Expect = 0.032
Identities = 70/318 (22%), Positives = 125/318 (39%), Gaps = 46/318 (14%)
Query: 103 REKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQ----RLSSHPVLSK 158
++ Q + E E + +EE A+ K +LE K + ++ L+ +L+ L +
Sbjct: 939 KKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 159 DRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLIN 218
DR E+ +L+ + +K + + +K+ E + T ++E E+++ L
Sbjct: 999 DR----IAEFTTNLTEEEEKSKSL------AKLKNKHEAMITDLEERLRREEKQRQELEK 1048
Query: 219 YYNRIK-DSCVKADKMTRSHKNVADDYIHTAACLHSL-----ALEEPTVIKKYLLKVAEL 272
+++ DS +D++ +A+ + A L +EE K LK
Sbjct: 1049 TRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALK---- 1104
Query: 273 FEKLRKVEGRVSS-DEDLK---------------LTELLRYYMLNIEAAKDLLYRRTKAL 316
K+R++E ++S EDL+ L E L +E D + +
Sbjct: 1105 --KIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 317 IDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNL 376
E L K ++ K EA QE QK Q E E+L + KRV A +
Sbjct: 1163 SKREQEVNILKKT--LEEEAKTHEAQIQEMRQKHSQAVEELAEQL--EQTKRVKANLEKA 1218
Query: 377 IEMSELEIKHARNNVSLL 394
+ E E N V +L
Sbjct: 1219 KQTLENERGELANEVKVL 1236
>gi|8922950 meiosis-specific nuclear structural 1 [Homo sapiens]
Length = 495
Score = 37.0 bits (84), Expect = 0.032
Identities = 51/256 (19%), Positives = 112/256 (43%), Gaps = 17/256 (6%)
Query: 120 EFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNT 179
++ +MK++ E + K + H+ ++ ++ +L+ ++ L + K
Sbjct: 148 KYEQMKRDAE-----IAKTMMEEHKRIIKEENAAEDKRNKAKAQYYLDLEKQLEEQEKKK 202
Query: 180 KEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKN 239
+E + K + DE++ + E D +Q+K +N R + K + R K
Sbjct: 203 QEAYEQLLKEKLM-IDEIV-RKIYEEDQLEKQQKLEKMNAMRRYIEEFQKEQALWRKKKR 260
Query: 240 VADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYM 299
++ + A + + + KV E EK +++ ++ KL E+LR
Sbjct: 261 --EEMEEENRKIIEFANMQQQREEDRMAKVQENEEKRLQLQNALTQ----KLEEMLRQRE 314
Query: 300 LNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKE 359
++E + LY+ +A I + +K K K++K + +++ K E + ++AKE
Sbjct: 315 -DLEQVRQELYQEEQAEIYKSKLKEEAEKKLRKQKEMK--QDFEEQMALK-ELVLQAAKE 370
Query: 360 ELINFKRKRVAAFRKN 375
E NF++ +A F ++
Sbjct: 371 EEENFRKTMLAKFAED 386
>gi|23397574 sorting nexin 33 [Homo sapiens]
Length = 574
Score = 37.0 bits (84), Expect = 0.032
Identities = 66/370 (17%), Positives = 136/370 (36%), Gaps = 67/370 (18%)
Query: 33 IDIPDALSERDKVKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPP 92
++ P ++ +K + K T SP V R+++ F WL++ L+ + + +P
Sbjct: 234 VEDPTKQTKFKGIKSYISYKLTPTHAASP---VYRRYKHFDWLYNRLLHK--FTVISVPH 288
Query: 93 APTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSS 152
P K + G ++ K K+ L +++ ++S
Sbjct: 289 LPEK--------------QATGRFEEDFIEKRKRRLI---------------LWMDHMTS 319
Query: 153 HPVLSKDRNFHVFLEYDQD----LSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDF 208
HPVLS+ F FL D + RR EM G F + E +++V+D
Sbjct: 320 HPVLSQYEGFQHFLSCLDDKQWKMGKRRAEKDEMVGASFLLTFQIPTE--HQDLQDVEDR 377
Query: 209 FEQEKNFLINYYNRIKDSCVKADKMTRSH-----KNVADDYIHTAACLHSLALEEP---T 260
+ K F + + A ++ R H K A HS ++ P
Sbjct: 378 VDTFKAFSKKMDDSVLQLSTVASELVRKHVGGFRKEFQKLGSAFQAISHSFQMDPPFCSE 437
Query: 261 VIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYE 320
+ + +E + ++ ++ ++ + L Y + D+++ + A +
Sbjct: 438 ALNSAISHTGRTYEAIGEMFAEQPKNDLFQMLDTLSLYQGLLSNFPDIIHLQKGAFAKVK 497
Query: 321 NSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMS 380
S + D+ R+ + A+ ++ C + + + E+ +F ++R
Sbjct: 498 ESQRMSDEGRMVQDE---ADGIRRRC----RVVGFALQAEMNHFHQRR------------ 538
Query: 381 ELEIKHARNN 390
EL+ KH N
Sbjct: 539 ELDFKHMMQN 548
>gi|21536423 amphiphysin isoform 2 [Homo sapiens]
Length = 653
Score = 35.4 bits (80), Expect = 0.093
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 298 YMLNIEAAKDLLYRRTKALIDYENSN---KALDKARLKSKD-VKLAEAHQQECCQKFEQL 353
Y+ K+ + +R++ L+DY+++ +AL ++ K + + AE Q+ + FE+
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 354 SESAKEELINFKRKRVAAFRKNLIEMSELEIK 385
+ +EEL + +RV + +S LE K
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
>gi|4502081 amphiphysin isoform 1 [Homo sapiens]
Length = 695
Score = 35.4 bits (80), Expect = 0.093
Identities = 23/92 (25%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 298 YMLNIEAAKDLLYRRTKALIDYENSN---KALDKARLKSKD-VKLAEAHQQECCQKFEQL 353
Y+ K+ + +R++ L+DY+++ +AL ++ K + + AE Q+ + FE+
Sbjct: 124 YLGQFPDIKNRIAKRSRKLVDYDSARHHLEALQSSKRKDESRISKAEEEFQKAQKVFEEF 183
Query: 354 SESAKEELINFKRKRVAAFRKNLIEMSELEIK 385
+ +EEL + +RV + +S LE K
Sbjct: 184 NVDLQEELPSLWSRRVGFYVNTFKNVSSLEAK 215
>gi|50658065 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 35.4 bits (80), Expect = 0.093
Identities = 45/206 (21%), Positives = 91/206 (44%), Gaps = 24/206 (11%)
Query: 191 VKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAAC 250
+++ E + KE+++ N + +KD+ K +K+T+ + + +
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQ---- 392
Query: 251 LHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLY 310
L LE+ V +K LK A K +K+E ++ D++ +E K +
Sbjct: 393 ---LDLEDVQVREK--LKHAT--SKAKKLEKQLQKDKE------------KVEEFKSIPA 433
Query: 311 RRTKALIDYENSNKALDKARLKS-KDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRV 369
+ + + N AL+K + K K +K ++ Q ++ ES ++EL+ F +
Sbjct: 434 KSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVN 493
Query: 370 AAFRKNLIEMSELEIKHARNNVSLLQ 395
A K + SEL+I +R+N ++ Q
Sbjct: 494 EARSKMDVAQSELDIYLSRHNTAVSQ 519
>gi|50658063 SMC4 structural maintenance of chromosomes 4-like 1
[Homo sapiens]
Length = 1288
Score = 35.4 bits (80), Expect = 0.093
Identities = 45/206 (21%), Positives = 91/206 (44%), Gaps = 24/206 (11%)
Query: 191 VKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAAC 250
+++ E + KE+++ N + +KD+ K +K+T+ + + +
Sbjct: 337 METQKEKIHEDTKEINEKSNILSNEMKAKNKDVKDTEKKLNKITKFIEENKEKFTQ---- 392
Query: 251 LHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLY 310
L LE+ V +K LK A K +K+E ++ D++ +E K +
Sbjct: 393 ---LDLEDVQVREK--LKHAT--SKAKKLEKQLQKDKE------------KVEEFKSIPA 433
Query: 311 RRTKALIDYENSNKALDKARLKS-KDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRV 369
+ + + N AL+K + K K +K ++ Q ++ ES ++EL+ F +
Sbjct: 434 KSNNIINETTTRNNALEKEKEKEEKKLKEVMDSLKQETQGLQKEKESREKELMGFSKSVN 493
Query: 370 AAFRKNLIEMSELEIKHARNNVSLLQ 395
A K + SEL+I +R+N ++ Q
Sbjct: 494 EARSKMDVAQSELDIYLSRHNTAVSQ 519
>gi|169169660 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/92 (22%), Positives = 48/92 (52%), Gaps = 15/92 (16%)
Query: 292 TELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFE 351
T+ LR +++N++ + L ++ L N+ + + L K+V Q+ C+K E
Sbjct: 315 TKFLRRHLMNLQQSWKLYLQKCLYLA---KKNQVIQQELLSMKEV-------QQKCKKLE 364
Query: 352 QLSESAKEELINFKRKRVAAFRKNLIEMSELE 383
++++ ++E++N K KN++E ++E
Sbjct: 365 EVNKILEQEVVNLK-----THEKNMVEFGDVE 391
>gi|169169929 PREDICTED: hypothetical protein [Homo sapiens]
Length = 460
Score = 34.7 bits (78), Expect = 0.16
Identities = 21/92 (22%), Positives = 48/92 (52%), Gaps = 15/92 (16%)
Query: 292 TELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFE 351
T+ LR +++N++ + L ++ L N+ + + L K+V Q+ C+K E
Sbjct: 315 TKFLRRHLMNLQQSWKLYLQKCLYLA---KKNQVIQQELLSMKEV-------QQKCKKLE 364
Query: 352 QLSESAKEELINFKRKRVAAFRKNLIEMSELE 383
++++ ++E++N K KN++E ++E
Sbjct: 365 EVNKILEQEVVNLK-----THEKNMVEFGDVE 391
>gi|56961680 coiled-coil domain containing 147 [Homo sapiens]
Length = 872
Score = 34.3 bits (77), Expect = 0.21
Identities = 46/182 (25%), Positives = 78/182 (42%), Gaps = 19/182 (10%)
Query: 210 EQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKV 269
EQ K L KD K K+ + D YI+ A+ L L IK ++
Sbjct: 411 EQAKRNLEGEIQNYKDEAQKQRKIIFHLEKERDRYINQASDLTQKVLMNMEDIK---VRE 467
Query: 270 AELFEKLRKV-EGRVSSDEDLKLTELLR----YYMLNIEAAKDL---LYRRTKALIDYEN 321
++F+ +K+ E + + L E +R Y N+ A+D + R+ K +I +
Sbjct: 468 TQIFDYRKKIAESEIKLKQQQNLYEAVRSDRNLYSKNLVEAQDEITDMKRKLKIMIHQVD 527
Query: 322 SNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSE 381
K + +K+ L + H ++ Q+ E+ E+ K EL K ++ A K+ IE E
Sbjct: 528 EL----KEDISAKESALVKLHLEQ--QRIEKEKETLKAEL--QKLRQQALETKHFIEKQE 579
Query: 382 LE 383
E
Sbjct: 580 AE 581
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 33.9 bits (76), Expect = 0.27
Identities = 50/248 (20%), Positives = 107/248 (43%), Gaps = 25/248 (10%)
Query: 103 REKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLS-SHPVLSKDRN 161
+ K+Q + E + +EE A++K+ + + + S ++ R ++ + ++R
Sbjct: 598 QSKIQSQMKVEKAHLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERA 657
Query: 162 FHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYN 221
L+ DL+ + K+ E + T +K D ++E L +
Sbjct: 658 KKAVLKDLSDLTAQAKSRDE------------ETATIITQLKLERDVHQRELKDLTSSLQ 705
Query: 222 RIK----DSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLR 277
+K + + K + K+ A+++I T L + +LEE + K + ++ +L +
Sbjct: 706 SVKTKHEQNIQELMKHFKKEKSEAENHIRT---LKAESLEEKNMAKIHRGQLEKLKSQCD 762
Query: 278 KVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVK 337
++ ++ +E+ L+Y L KD L R K + E + +++ARL+ KD
Sbjct: 763 RLTEELTQNENENKKLKLKYQCL-----KDQLEEREKHISIEEEHLRRMEEARLQLKDQL 817
Query: 338 LAEAHQQE 345
L +QE
Sbjct: 818 LCLETEQE 825
>gi|122937396 coiled-coil domain containing 150 [Homo sapiens]
Length = 1101
Score = 33.9 bits (76), Expect = 0.27
Identities = 82/422 (19%), Positives = 164/422 (38%), Gaps = 69/422 (16%)
Query: 6 ELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQSPEFSV 65
ELL Q+++ + +L + L D + + D+ L E +K + + S
Sbjct: 274 ELLAQEQKKKEELEIATSQLKSDLTSRDDLISKLVEENK---------------NLQISF 318
Query: 66 TRQHEDFVWLHDTLI---ETTDYAGLIIPPAPTKPDFDG------PREKM------QKLG 110
++HE+ +L ++ E ++ A ++ K EK Q +
Sbjct: 319 NKEHEENAYLRSEIMSLHEASEKAQVLNDQLTKKCSELSCMLQTVTMEKARIIADHQAIL 378
Query: 111 EGEGSMTKEEFAKMKQELEAEYLAVFKK--TVSSHEVFLQRLSSHPVLSKDRNFHVFLEY 168
+ E M + F + L+A + ++ + TV + + LQ H +L ++ ++
Sbjct: 379 QVEQKMMTQTFQEQNLLLDAAHASITNELQTVQNEKTQLQAHLDHLILEHNQ----CIQK 434
Query: 169 DQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFL------------ 216
QD R KE+ +S + L ++E E+++ F
Sbjct: 435 AQDAEKRTAVQKELL----ESTIARLRGELEASMQEKKSLLEEKERFQREVNKTEKEIVQ 490
Query: 217 --INYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPT-----VIKKYLLKV 269
N + + V + +T + + + ++ H A + SL L++ T + ++ + K+
Sbjct: 491 ERCNLEKELAKNKVDINTLTHNLQTLEEENKHLADQMASLELQQVTSDYHGLAQQKVEKI 550
Query: 270 AELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKAL-IDYENSNKALDK 328
E KL G++ +K E + D L + K L Y +N L
Sbjct: 551 TESKNKLAYENGKLQIK--VKQLEEQVQSFTDTSLQNDHLRKMNKYLQTKYAQANSELSA 608
Query: 329 ARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHAR 388
R+ ++ A+AH +E + + E +KEEL + R AA +++ +LE R
Sbjct: 609 KRVH---LQQADAHLKEV----KSILERSKEELSRTVKCRNAALKESQKLKEDLEAVEDR 661
Query: 389 NN 390
N
Sbjct: 662 EN 663
Score = 30.4 bits (67), Expect = 3.0
Identities = 25/96 (26%), Positives = 42/96 (43%), Gaps = 7/96 (7%)
Query: 271 ELFEKLRKVEGRVSSDEDLKLTELLR-YYMLNIEAAKDLLYRRTKALIDYENSNKALDKA 329
E F+ E +V ++ + E LR + E K + R L KALD+A
Sbjct: 807 ETFKDRMTEESKVEAELHAERIEALRKQFQTERETTKKVAQREVAEL------KKALDEA 860
Query: 330 RLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFK 365
+S +V ++ + E++ ES KE++ N K
Sbjct: 861 NFRSVEVSRTNRELRQKLAELEKILESNKEKIKNQK 896
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.132 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,084,883
Number of Sequences: 37866
Number of extensions: 611479
Number of successful extensions: 2578
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 104
Number of HSP's that attempted gapping in prelim test: 2479
Number of HSP's gapped (non-prelim): 204
length of query: 404
length of database: 18,247,518
effective HSP length: 105
effective length of query: 299
effective length of database: 14,271,588
effective search space: 4267204812
effective search space used: 4267204812
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.