Guide to the Human Genome
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Search of human proteins with 7657025

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7657025 dickkopf homolog 4 precursor [Homo sapiens]
         (224 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7657025 dickkopf homolog 4 precursor [Homo sapiens]                481   e-136
gi|7657023 dickkopf homolog 2 precursor [Homo sapiens]                154   4e-38
gi|7110719 dickkopf homolog 1 precursor [Homo sapiens]                146   2e-35
gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]                72   4e-13
gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]                72   4e-13
gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]                72   4e-13
gi|14165282 prokineticin 1 [Homo sapiens]                              45   5e-05
gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens]          41   0.001
gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens]         36   0.030
gi|86990448 chromosome 1 open reading frame 187 [Homo sapiens]         35   0.040
gi|18252045 ADAM metallopeptidase domain 33 isoform alpha prepro...    35   0.068
gi|11968150 GDNF-inducible zinc finger protein 1 [Homo sapiens]        33   0.26 
gi|24041040 ADAM metallopeptidase domain 33 isoform beta preprop...    32   0.34 
gi|239751308 PREDICTED: keratin associated protein 4-9 isoform 1...    32   0.44 
gi|122937343 platelet endothelial aggregation receptor 1 [Homo s...    32   0.57 
gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Ho...    31   0.98 
gi|225690551 keratin associated protein 4-9 [Homo sapiens]             30   1.3  
gi|154759249 keratin associated protein 10-11 [Homo sapiens]           30   1.7  
gi|183396797 keratin associated protein KRTAP2.1A [Homo sapiens]       30   2.2  
gi|15082232 keratin associated protein 2-4 [Homo sapiens]              30   2.2  
gi|225690576 keratin associated protein 2-2 [Homo sapiens]             30   2.2  
gi|113427417 PREDICTED: similar to keratin associated protein 2-...    30   2.2  
gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]                30   2.2  
gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 iso...    30   2.2  
gi|118572608 keratin associated protein 4-5 [Homo sapiens]             30   2.2  
gi|22547108 tumor necrosis factor receptor superfamily, member 1...    29   2.8  
gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo ...    29   2.8  
gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo ...    29   2.8  
gi|30089980 chordin [Homo sapiens]                                     29   3.7  
gi|56699495 WAP four-disulfide core domain 2 precursor [Homo sap...    29   3.7  

>gi|7657025 dickkopf homolog 4 precursor [Homo sapiens]
          Length = 224

 Score =  481 bits (1238), Expect = e-136
 Identities = 224/224 (100%), Positives = 224/224 (100%)

Query: 1   MVAAVLLGLSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEK 60
           MVAAVLLGLSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEK
Sbjct: 1   MVAAVLLGLSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEK 60

Query: 61  PFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPV 120
           PFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPV
Sbjct: 61  PFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPV 120

Query: 121 QENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRG 180
           QENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRG
Sbjct: 121 QENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRG 180

Query: 181 HKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL 224
           HKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL
Sbjct: 181 HKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHARLRVCQKIEKL 224


>gi|7657023 dickkopf homolog 2 precursor [Homo sapiens]
          Length = 259

 Score =  154 bits (390), Expect = 4e-38
 Identities = 84/199 (42%), Positives = 110/199 (55%), Gaps = 15/199 (7%)

Query: 34  GARKGSQ------CLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVN 87
           G++KG        C SD +C   ++C  P      C  CR  ++RC RD MCCP T C N
Sbjct: 65  GSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPSTRCNN 124

Query: 88  DVCTTMEDATPILERQLDEQDGT-HAEGTTGHPVQEN---QPKRKPSIKKSQGRKGQEGE 143
            +C  + ++  IL   +   DGT H +   GH    +   Q   +P  K S   KG EG+
Sbjct: 125 GICIPVTES--ILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSH-IKGHEGD 181

Query: 144 SCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCR 203
            CLR+ DC  G CCARHFWTKICKPVL +G+VC+++  K  +   EIFQRCDC  GL C+
Sbjct: 182 PCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQ-RKKGSHGLEIFQRCDCAKGLSCK 240

Query: 204 S-QLTSNRQHARLRVCQKI 221
             +  +    ARL VCQKI
Sbjct: 241 VWKDATYSSKARLHVCQKI 259


>gi|7110719 dickkopf homolog 1 precursor [Homo sapiens]
          Length = 266

 Score =  146 bits (368), Expect = 2e-35
 Identities = 77/188 (40%), Positives = 97/188 (51%), Gaps = 15/188 (7%)

Query: 41  CLSDTDCNTRKFCLQPRDEKP----FCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDA 96
           C  D +C T ++C  P          C  CR  R+RC R AMCCPG  C N +C + +  
Sbjct: 85  CAEDEECGTDEYCASPTRGGDAGVQICLACRKRRKRCMRHAMCCPGNYCKNGICVSSDQN 144

Query: 97  --TPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPG 154
                +E  + E  G        H   +   +R     K    KGQEG  CLR+ DC  G
Sbjct: 145 HFRGEIEETITESFGND------HSTLDGYSRRTTLSSKMYHTKGQEGSVCLRSSDCASG 198

Query: 155 LCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNR--QH 212
           LCCARHFW+KICKPVL EGQVC++   K  +   EIFQRC CG GL CR Q   ++    
Sbjct: 199 LCCARHFWSKICKPVLKEGQVCTKHRRKG-SHGLEIFQRCYCGEGLSCRIQKDHHQASNS 257

Query: 213 ARLRVCQK 220
           +RL  CQ+
Sbjct: 258 SRLHTCQR 265


>gi|66346689 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 57/215 (26%), Positives = 78/215 (36%), Gaps = 65/215 (30%)

Query: 17  GALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRD 76
           G +V     I S  D  G R+  +C+ D DC    +C Q    +  C  CRG R  C RD
Sbjct: 124 GQMVFSETVITSVGDEEG-RRSHECIIDEDCGPSMYC-QFASFQYTCQPCRGQRMLCTRD 181

Query: 77  AMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQG 136
           + CC   LCV   CT M                                           
Sbjct: 182 SECCGDQLCVWGHCTKM------------------------------------------A 199

Query: 137 RKGQEGESCLRTFDCGPGLCCA--RHFWTKICKPVLLEGQVCSRRGHKDTAQAPEI---- 190
            +G  G  C    DC PGLCCA  R     +C P+ +EG++C    H   ++  ++    
Sbjct: 200 TRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELC----HDPASRLLDLITWE 255

Query: 191 ------FQRCDCGPGLLCRSQLTSNRQHARLRVCQ 219
                   RC C  GLLC+        H+ + VC+
Sbjct: 256 LEPDGALDRCPCASGLLCQP-----HSHSLVYVCK 285


>gi|40548393 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 57/215 (26%), Positives = 78/215 (36%), Gaps = 65/215 (30%)

Query: 17  GALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRD 76
           G +V     I S  D  G R+  +C+ D DC    +C Q    +  C  CRG R  C RD
Sbjct: 124 GQMVFSETVITSVGDEEG-RRSHECIIDEDCGPSMYC-QFASFQYTCQPCRGQRMLCTRD 181

Query: 77  AMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQG 136
           + CC   LCV   CT M                                           
Sbjct: 182 SECCGDQLCVWGHCTKM------------------------------------------A 199

Query: 137 RKGQEGESCLRTFDCGPGLCCA--RHFWTKICKPVLLEGQVCSRRGHKDTAQAPEI---- 190
            +G  G  C    DC PGLCCA  R     +C P+ +EG++C    H   ++  ++    
Sbjct: 200 TRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELC----HDPASRLLDLITWE 255

Query: 191 ------FQRCDCGPGLLCRSQLTSNRQHARLRVCQ 219
                   RC C  GLLC+        H+ + VC+
Sbjct: 256 LEPDGALDRCPCASGLLCQP-----HSHSLVYVCK 285


>gi|40548389 dickkopf homolog 3 precursor [Homo sapiens]
          Length = 350

 Score = 72.0 bits (175), Expect = 4e-13
 Identities = 57/215 (26%), Positives = 78/215 (36%), Gaps = 65/215 (30%)

Query: 17  GALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRD 76
           G +V     I S  D  G R+  +C+ D DC    +C Q    +  C  CRG R  C RD
Sbjct: 124 GQMVFSETVITSVGDEEG-RRSHECIIDEDCGPSMYC-QFASFQYTCQPCRGQRMLCTRD 181

Query: 77  AMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQG 136
           + CC   LCV   CT M                                           
Sbjct: 182 SECCGDQLCVWGHCTKM------------------------------------------A 199

Query: 137 RKGQEGESCLRTFDCGPGLCCA--RHFWTKICKPVLLEGQVCSRRGHKDTAQAPEI---- 190
            +G  G  C    DC PGLCCA  R     +C P+ +EG++C    H   ++  ++    
Sbjct: 200 TRGSNGTICDNQRDCQPGLCCAFQRGLLFPVCTPLPVEGELC----HDPASRLLDLITWE 255

Query: 191 ------FQRCDCGPGLLCRSQLTSNRQHARLRVCQ 219
                   RC C  GLLC+        H+ + VC+
Sbjct: 256 LEPDGALDRCPCASGLLCQP-----HSHSLVYVCK 285


>gi|14165282 prokineticin 1 [Homo sapiens]
          Length = 105

 Score = 45.1 bits (105), Expect = 5e-05
 Identities = 22/62 (35%), Positives = 27/62 (43%), Gaps = 3/62 (4%)

Query: 144 SCLRTFDCGPGLCCARHFW---TKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGL 200
           +C R   CG G CCA   W    ++C P+  EG+ C    HK           C C P L
Sbjct: 25  ACERDVQCGAGTCCAISLWLRGLRMCTPLGREGEECHPGSHKVPFFRKRKHHTCPCLPNL 84

Query: 201 LC 202
           LC
Sbjct: 85  LC 86


>gi|17530787 prokineticin 2 isoform b precursor [Homo sapiens]
          Length = 108

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 21/62 (33%), Positives = 26/62 (41%), Gaps = 3/62 (4%)

Query: 144 SCLRTFDCGPGLCCARHFWTK---ICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGL 200
           +C +   CG G+CCA   W K   IC P+   G  C     K       +   C C PGL
Sbjct: 33  ACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKVPFFGRRMHHTCPCLPGL 92

Query: 201 LC 202
            C
Sbjct: 93  AC 94


>gi|187167261 prokineticin 2 isoform a precursor [Homo sapiens]
          Length = 129

 Score = 35.8 bits (81), Expect = 0.030
 Identities = 24/83 (28%), Positives = 31/83 (37%), Gaps = 24/83 (28%)

Query: 144 SCLRTFDCGPGLCCARHFWTK---ICKPVLLEGQVC--------------SRRGHKDTAQ 186
           +C +   CG G+CCA   W K   IC P+   G  C               RR  K + +
Sbjct: 33  ACDKDSQCGGGMCCAVSIWVKSIRICTPMGKLGDSCHPLTRKNNFGNGRQERRKRKRSKR 92

Query: 187 APEI-------FQRCDCGPGLLC 202
             E+          C C PGL C
Sbjct: 93  KKEVPFFGRRMHHTCPCLPGLAC 115


>gi|86990448 chromosome 1 open reading frame 187 [Homo sapiens]
          Length = 349

 Score = 35.4 bits (80), Expect = 0.040
 Identities = 29/105 (27%), Positives = 41/105 (39%), Gaps = 26/105 (24%)

Query: 121 QENQPKRKPSIKKSQGRKGQ-----------EGESCLRTFDCGPGLCCARHFWTKICKPV 169
           ++ +P   PS KK +  +G+           EGE C    DC PG CC       +C P 
Sbjct: 239 EDLKPDGWPSAKKKEKHRGKLSSDGNETSPAEGEPCDHHQDCLPGTCC--DLREHLCTP- 295

Query: 170 LLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQLTSNRQHAR 214
                    RG  +     + F  C C  GL C ++   NR+  R
Sbjct: 296 -------HNRGLNN-----KCFDDCMCVEGLRCYAKFHRNRRVTR 328



 Score = 29.3 bits (64), Expect = 2.8
 Identities = 15/45 (33%), Positives = 19/45 (42%), Gaps = 8/45 (17%)

Query: 41  CLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLC 85
           CL  T C+ R+    P +        RGL  +C  D MC  G  C
Sbjct: 280 CLPGTCCDLREHLCTPHN--------RGLNNKCFDDCMCVEGLRC 316


>gi|18252045 ADAM metallopeptidase domain 33 isoform alpha
           preproprotein [Homo sapiens]
          Length = 813

 Score = 34.7 bits (78), Expect = 0.068
 Identities = 49/209 (23%), Positives = 68/209 (32%), Gaps = 33/209 (15%)

Query: 36  RKGSQCLSDTDCNTR-------KFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVND 88
           R G+QC +  DC  R         C Q   +      C G    C  D     G+ C   
Sbjct: 452 RPGAQC-AHGDCCVRCLLKPAGALCRQAMGDCDLPEFCTGTSSHCPPDVYLLDGSPCARG 510

Query: 89  VCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCL-- 146
                + A P LE+Q  +       G   HP  E   +   S   + G  GQ+ E     
Sbjct: 511 SGYCWDGACPTLEQQCQQ-----LWGPGSHPAPEACFQVVNSAGDAHGNCGQDSEGHFLP 565

Query: 147 ---RTFDCGPGLC-------CARHFWTKICKPVLLEGQVCSRRG-------HKDTAQAPE 189
              R   CG   C        A H    +   V L+GQ  + RG         D      
Sbjct: 566 CAGRDALCGKLQCQGGKPSLLAPHM-VPVDSTVHLDGQEVTCRGALALPSAQLDLLGLGL 624

Query: 190 IFQRCDCGPGLLCRSQLTSNRQHARLRVC 218
           +     CGP ++C+S+         L+ C
Sbjct: 625 VEPGTQCGPRMVCQSRRCRKNAFQELQRC 653


>gi|11968150 GDNF-inducible zinc finger protein 1 [Homo sapiens]
          Length = 711

 Score = 32.7 bits (73), Expect = 0.26
 Identities = 32/134 (23%), Positives = 50/134 (37%), Gaps = 25/134 (18%)

Query: 80  CPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKG 139
           CP     + V T ME        Q+ + +G  A    G  ++E   K  P  ++ +  + 
Sbjct: 260 CPQDQSPDRVGTEME--------QVSKNEGCQA----GAELEELSKKAGPEEEEEEEEED 307

Query: 140 QEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCD-CGP 198
           +EGE     F C             IC+   L  +   +        A E+  RCD CG 
Sbjct: 308 EEGEKKKSNFKC------------SICEKAFLYEKSFLKHSKHRHGVATEVVYRCDTCGQ 355

Query: 199 GLLCRSQLTSNRQH 212
               R  L S+++H
Sbjct: 356 TFANRCNLKSHQRH 369


>gi|24041040 ADAM metallopeptidase domain 33 isoform beta
           preproprotein [Homo sapiens]
          Length = 787

 Score = 32.3 bits (72), Expect = 0.34
 Identities = 47/195 (24%), Positives = 63/195 (32%), Gaps = 33/195 (16%)

Query: 36  RKGSQCLSDTDCNTR-------KFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVND 88
           R G+QC +  DC  R         C Q   +      C G    C  D     G+ C   
Sbjct: 452 RPGAQC-AHGDCCVRCLLKPAGALCRQAMGDCDLPEFCTGTSSHCPPDVYLLDGSPCARG 510

Query: 89  VCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCL-- 146
                + A P LE+Q  +       G   HP  E   +   S   + G  GQ+ E     
Sbjct: 511 SGYCWDGACPTLEQQCQQ-----LWGPGSHPAPEACFQVVNSAGDAHGNCGQDSEGHFLP 565

Query: 147 ---RTFDCGPGLC-------CARHFWTKICKPVLLEGQVCSRRG-------HKDTAQAPE 189
              R   CG   C        A H    +   V L+GQ  + RG         D      
Sbjct: 566 CAGRDALCGKLQCQGGKPSLLAPHM-VPVDSTVHLDGQEVTCRGALALPSAQLDLLGLGL 624

Query: 190 IFQRCDCGPGLLCRS 204
           +     CGP ++C S
Sbjct: 625 VEPGTQCGPRMVCNS 639


>gi|239751308 PREDICTED: keratin associated protein 4-9 isoform 1
           [Homo sapiens]
          Length = 210

 Score = 32.0 bits (71), Expect = 0.44
 Identities = 34/141 (24%), Positives = 43/141 (30%), Gaps = 20/141 (14%)

Query: 39  SQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMC---CPGTLCVNDVCTTMED 95
           S C     C +   C QP   +P C      R  C R + C   C    C   VC     
Sbjct: 47  SSCCRPQCCQS--VCCQPTCSRPSCCQTTCCRTTCYRPSCCVSSCCRPQCCQPVCCQPTC 104

Query: 96  ATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGL 155
             P           +  E T  HP        +PS   S   K Q    C ++  C P  
Sbjct: 105 CRP-----------SCCETTCCHPRCCISSCCRPSCCVSSCCKPQ----CCQSVCCQPNC 149

Query: 156 CCARHFWTKICKPVLLEGQVC 176
           C      +  C+P   E   C
Sbjct: 150 CRPSCSISSCCRPSCCESSCC 170



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)

Query: 39  SQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVC 90
           S C     C +   C QP   +P C+     R  C  ++ CC    CV  VC
Sbjct: 132 SSCCKPQCCQS--VCCQPNCCRPSCSISSCCRPSC-CESSCCRPCCCVRPVC 180


>gi|122937343 platelet endothelial aggregation receptor 1 [Homo
           sapiens]
          Length = 1037

 Score = 31.6 bits (70), Expect = 0.57
 Identities = 47/174 (27%), Positives = 55/174 (31%), Gaps = 33/174 (18%)

Query: 38  GSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRR-RCQRDAMCCPGTL---CVNDVCTTM 93
           G  C +   C     CL    E   C    G R   CQR   C PG     CV   C   
Sbjct: 573 GVNCSNTCTCKNGGTCLP---ENGNCVCAPGFRGPSCQRS--CQPGRYGKRCVPCKCANH 627

Query: 94  EDATPILERQLDEQDGTH--AEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDC 151
               P         +GT     G TG    +  P             G  GE+C +T  C
Sbjct: 628 SFCHP--------SNGTCYCLAGWTGPDCSQPCPP------------GHWGENCAQTCQC 667

Query: 152 GPGLCCARHFWTKICKPVLLEGQVCSRRGHKDTAQAPEIFQRCDCGPGLLCRSQ 205
             G  C     + IC P+   G  C       T  A    Q C CGPG  C  +
Sbjct: 668 HHGGTCHPQDGSCIC-PLGWTGHHCLEGCPLGTFGA-NCSQPCQCGPGEKCHPE 719


>gi|21464119 methyl-CpG binding domain protein 1 isoform PCM1 [Homo
           sapiens]
          Length = 556

 Score = 30.8 bits (68), Expect = 0.98
 Identities = 36/160 (22%), Positives = 51/160 (31%), Gaps = 12/160 (7%)

Query: 9   LSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRG 68
           L  LC    A  + FN  +      G      C +  DC     CL+P          + 
Sbjct: 150 LKTLCKDCRAQRIAFNREQRMFKSRGCGVCRGCQTQEDCGHCPICLRP-PRPGLRRQWKC 208

Query: 69  LRRRCQRDAMCCPGTLCVNDVCTTMEDAT----PILERQLDEQDGTHAEGTTGHPVQE-- 122
           ++RRC R         C + +            P    Q  E    H       P  E  
Sbjct: 209 VQRRCLRGKHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPHPRALAPSPPAEFI 268

Query: 123 ----NQPKRKPSIKKSQGRKGQEGESCLRTFDCGP-GLCC 157
               ++ + +P   + Q RK     +CLR  DCG    CC
Sbjct: 269 YYCVDEDELQPYTNRRQNRKCGACAACLRRMDCGRCDFCC 308


>gi|225690551 keratin associated protein 4-9 [Homo sapiens]
          Length = 210

 Score = 30.4 bits (67), Expect = 1.3
 Identities = 33/141 (23%), Positives = 42/141 (29%), Gaps = 20/141 (14%)

Query: 39  SQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMC---CPGTLCVNDVCTTMED 95
           S C     C +   C QP   +P C      R  C R + C   C    C    C     
Sbjct: 47  SSCCRPQCCQS--VCCQPTCSRPSCCQTTCCRTTCYRPSCCVSSCCRPQCCQPACCQPTC 104

Query: 96  ATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGL 155
             P           +  E T  HP        +PS   S   K Q    C ++  C P  
Sbjct: 105 CRP-----------SCCETTCCHPRCCISSCCRPSCCVSSCCKPQ----CCQSVCCQPNC 149

Query: 156 CCARHFWTKICKPVLLEGQVC 176
           C      +  C+P   E   C
Sbjct: 150 CRPSCSISSCCRPSCCESSCC 170



 Score = 28.1 bits (61), Expect = 6.3
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 3/52 (5%)

Query: 39  SQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVC 90
           S C     C +   C QP   +P C+     R  C  ++ CC    CV  VC
Sbjct: 132 SSCCKPQCCQS--VCCQPNCCRPSCSISSCCRPSC-CESSCCRPCCCVRPVC 180


>gi|154759249 keratin associated protein 10-11 [Homo sapiens]
          Length = 298

 Score = 30.0 bits (66), Expect = 1.7
 Identities = 40/170 (23%), Positives = 58/170 (34%), Gaps = 15/170 (8%)

Query: 9   LSWLCSPLGALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRG 68
           LS +C+P+  +        SS     A + S C S    +    C Q    +P C T   
Sbjct: 43  LSLVCTPVSCV--------SSPCCQAACEPSACQSGCTSSCTPSCCQQSSCQPACCTSSP 94

Query: 69  LRRRCQRDAMCCPGTLCVNDVCTTME--DATPILERQLDEQDGTHAEGTTGHPVQENQPK 126
            ++ C    +CC  T+C   VC       A     RQ   Q    A  +   P       
Sbjct: 95  CQQAC-CVPVCCK-TVCCKPVCCVPVCCGAASSCCRQSSCQPACCASSSC-QPACCVPVC 151

Query: 127 RKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVC 176
            KP    S     ++  SC +   C P  C +  +    C PV  +   C
Sbjct: 152 CKPVCCVS--TCSEDSSSCCQQSSCQPACCTSSSYQQACCVPVCCKTVYC 199


>gi|183396797 keratin associated protein KRTAP2.1A [Homo sapiens]
          Length = 128

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 19/61 (31%), Positives = 22/61 (36%), Gaps = 12/61 (19%)

Query: 41 CLSDTDCNT---RKFCLQPRDEKPFCATCR--------GLRRRCQRDAMCCPGTLCVNDV 89
          C     C T   R     PR  +P C  CR         L+  C R   CCP + C   V
Sbjct: 30 CCRPVTCQTTVCRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPSS-CTAVV 88

Query: 90 C 90
          C
Sbjct: 89 C 89


>gi|15082232 keratin associated protein 2-4 [Homo sapiens]
          Length = 128

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 19/61 (31%), Positives = 22/61 (36%), Gaps = 12/61 (19%)

Query: 41 CLSDTDCNT---RKFCLQPRDEKPFCATCR--------GLRRRCQRDAMCCPGTLCVNDV 89
          C     C T   R     PR  +P C  CR         L+  C R   CCP + C   V
Sbjct: 30 CCRPVTCQTTVCRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPSS-CTAVV 88

Query: 90 C 90
          C
Sbjct: 89 C 89


>gi|225690576 keratin associated protein 2-2 [Homo sapiens]
          Length = 123

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 19/61 (31%), Positives = 22/61 (36%), Gaps = 12/61 (19%)

Query: 41 CLSDTDCNT---RKFCLQPRDEKPFCATCR--------GLRRRCQRDAMCCPGTLCVNDV 89
          C     C T   R     PR  +P C  CR         L+  C R   CCP + C   V
Sbjct: 30 CCRPVTCQTTVCRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPSS-CTAVV 88

Query: 90 C 90
          C
Sbjct: 89 C 89


>gi|113427417 PREDICTED: similar to keratin associated protein 2-4
          [Homo sapiens]
          Length = 128

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 19/61 (31%), Positives = 22/61 (36%), Gaps = 12/61 (19%)

Query: 41 CLSDTDCNT---RKFCLQPRDEKPFCATCR--------GLRRRCQRDAMCCPGTLCVNDV 89
          C     C T   R     PR  +P C  CR         L+  C R   CCP + C   V
Sbjct: 30 CCRPVTCQTTVCRPVTCVPRCTRPICEPCRRPVCCDPCSLQEGCCRPITCCPSS-CTAVV 88

Query: 90 C 90
          C
Sbjct: 89 C 89


>gi|110347457 EGF-like-domain, multiple 3 [Homo sapiens]
          Length = 1541

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 22/67 (32%), Positives = 25/67 (37%), Gaps = 8/67 (11%)

Query: 139  GQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEGQVCS---RRGHKDTAQAPEIFQRCD 195
            G  GE C +  DC  G  C       +C P    G  C+   RRG       P     CD
Sbjct: 1424 GSFGEGCHQRCDCDGGAPCDPVTGLCLCPPG-RSGATCNLDCRRGQ----FGPSCTLHCD 1478

Query: 196  CGPGLLC 202
            CG G  C
Sbjct: 1479 CGGGADC 1485


>gi|132566527 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11
           isoform 3 [Homo sapiens]
          Length = 970

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 22/67 (32%), Positives = 33/67 (49%), Gaps = 9/67 (13%)

Query: 93  MEDATPILERQLDEQDGTHAEGTTGHPVQE-NQPKRKPSIKKSQGRKGQEGESCLRTFDC 151
           +++    L++ L  + GT  EG+ G PV E  QP  +      QG +  EG  C R+   
Sbjct: 808 LQEKMAYLDQTLSPRPGTPREGSGGEPVHEGRQPVHR------QGHQAPEG-FCQRSAP- 859

Query: 152 GPGLCCA 158
           GP +C A
Sbjct: 860 GPAICPA 866


>gi|118572608 keratin associated protein 4-5 [Homo sapiens]
          Length = 181

 Score = 29.6 bits (65), Expect = 2.2
 Identities = 17/60 (28%), Positives = 23/60 (38%), Gaps = 9/60 (15%)

Query: 39  SQCLSDTDCNT--------RKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVC 90
           S C   T C+         R +C +    +P C      R  C R   CCP + CV+  C
Sbjct: 48  SVCYQPTCCHPSCCISSCCRPYCCESSCCRPCCCQTTCCRTTCCRTTCCCP-SCCVSSCC 106


>gi|22547108 tumor necrosis factor receptor superfamily, member 10d
           precursor [Homo sapiens]
          Length = 386

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 21/73 (28%), Positives = 29/73 (39%), Gaps = 5/73 (6%)

Query: 34  GARKGSQCLS--DTDCNTRKFCLQPRDEKPFCATCR-GLRRRCQRDAMCCPGT--LCVND 88
           G    S C +  DT C   K   Q ++    C TCR G  R   + + C P +   C N+
Sbjct: 124 GQTNKSSCTTTRDTVCQCEKGSFQDKNSPEMCRTCRTGCPRGMVKVSNCTPRSDIKCKNE 183

Query: 89  VCTTMEDATPILE 101
              +    TP  E
Sbjct: 184 SAASSTGKTPAAE 196


>gi|21464115 methyl-CpG binding domain protein 1 isoform 2 [Homo
           sapiens]
          Length = 586

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 32/129 (24%), Positives = 46/129 (35%), Gaps = 27/129 (20%)

Query: 50  RKFCLQPRDEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDG 109
           R+ CL+  +    C  CRG +   Q D   CP  +C+      +      ++R+     G
Sbjct: 212 RRRCLRIVERSRGCGVCRGCQT--QEDCGHCP--ICLRPPRPGLRRQWKCVQRRCLR--G 265

Query: 110 THAEGTTG-------------------HPVQENQPKR-KPSIKKSQGRKGQEGESCLRTF 149
            HA    G                    P Q  +P   +P   + Q RK     +CLR  
Sbjct: 266 KHARRKGGCDSKMAARRRPGAQPLPPPPPSQSPEPTEPQPYTNRRQNRKCGACAACLRRM 325

Query: 150 DCGP-GLCC 157
           DCG    CC
Sbjct: 326 DCGRCDFCC 334


>gi|50658079 tubulin tyrosine ligase-like family, member 5 [Homo
           sapiens]
          Length = 1281

 Score = 29.3 bits (64), Expect = 2.8
 Identities = 32/141 (22%), Positives = 56/141 (39%), Gaps = 14/141 (9%)

Query: 17  GALVLDFNNIRSSADLHGARKGSQCLSDTDCNTRKFCLQPRDEKPFCATCRGLRRRCQRD 76
           GA  L   ++ S A LH A    + LS          L+ R  +   +  R +R +    
Sbjct: 522 GAPELKIESLNSKAKLHAALYERKLLS----------LEVRKRRRRSSRLRAMRPKYP-- 569

Query: 77  AMCCPGTLCVNDVCTTMEDATPILERQLDEQDGTHAEGTTGHPVQENQPKRKPSIKKSQG 136
            +  P  + V     + E+    L+ + +EQ+ +  E      ++ENQ K  PS+     
Sbjct: 570 VITQPAEMNVKTETESEEEEEVALDNEDEEQEASQEESAGF--LRENQAKYTPSLTALVE 627

Query: 137 RKGQEGESCLRTFDCGPGLCC 157
              +E    +R ++   G CC
Sbjct: 628 NTPKENSMKVREWNNKGGHCC 648


>gi|30089980 chordin [Homo sapiens]
          Length = 955

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 33/118 (27%), Positives = 42/118 (35%), Gaps = 23/118 (19%)

Query: 61  PFCATCRGLRRRCQRDAMCCPGTLCVN---------DVCTTMEDA--TPILERQLDEQDG 109
           P C+ C   RR    D + CP   C +          VC   +D    P L R  D  +G
Sbjct: 724 PLCSLCTCQRRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEG 783

Query: 110 TH--------AEGTTGHPVQENQPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCAR 159
            +        A GT  HPV       K ++      KG  GE       C P L CA+
Sbjct: 784 CYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTC---KGGTGEVHCEKVQC-PRLACAQ 837


>gi|56699495 WAP four-disulfide core domain 2 precursor [Homo
           sapiens]
          Length = 124

 Score = 28.9 bits (63), Expect = 3.7
 Identities = 20/75 (26%), Positives = 30/75 (40%), Gaps = 16/75 (21%)

Query: 40  QCLSDTDC---------NTRKFCLQPRDEKPFCATCR------GL-RRRCQRDAMCCPGT 83
           +C+SD++C             FC  P D++  C          GL R +CQ D+ C    
Sbjct: 48  ECVSDSECADNLKCCSAGCATFCSLPNDKEGSCPQVNINFPQLGLCRDQCQVDSQCPGQM 107

Query: 84  LCVNDVCTTMEDATP 98
            C  + C  +   TP
Sbjct: 108 KCCRNGCGKVSCVTP 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,606,556
Number of Sequences: 37866
Number of extensions: 551481
Number of successful extensions: 1661
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 9
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 1587
Number of HSP's gapped (non-prelim): 92
length of query: 224
length of database: 18,247,518
effective HSP length: 98
effective length of query: 126
effective length of database: 14,536,650
effective search space: 1831617900
effective search space used: 1831617900
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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