Guide to the Human Genome
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Search of human proteins with 7305013

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
         (351 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]            698   0.0  
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]           371   e-103
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]           371   e-103
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]            331   5e-91
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]         209   2e-54
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]         195   6e-50
gi|134244587 endothelial differentiation, sphingolipid G-protein...   189   4e-48
gi|13540517 endothelial differentiation, sphingolipid G-protein-...   189   4e-48
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa...   181   7e-46
gi|4885325 G protein-coupled receptor 3 [Homo sapiens]                134   2e-31
gi|4885341 G protein-coupled receptor 6 [Homo sapiens]                127   1e-29
gi|4885295 G protein-coupled receptor 12 [Homo sapiens]               127   2e-29
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]          117   2e-26
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]          117   2e-26
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]          117   2e-26
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]          117   2e-26
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]           117   2e-26
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]          117   2e-26
gi|5174535 melanocortin 5 receptor [Homo sapiens]                     114   1e-25
gi|119508433 melanocortin 4 receptor [Homo sapiens]                   105   6e-23
gi|170671732 melanocortin 3 receptor [Homo sapiens]                   105   8e-23
gi|5921992 adenosine A2a receptor [Homo sapiens]                      100   1e-21
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]          96   5e-20
gi|115305569 adenosine A1 receptor [Homo sapiens]                      91   2e-18
gi|4501947 adenosine A1 receptor [Homo sapiens]                        91   2e-18
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap...    90   3e-18
gi|4501951 adenosine A2b receptor [Homo sapiens]                       88   1e-17
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]                 88   1e-17
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]       83   3e-16
gi|193083134 melanocortin 1 receptor [Homo sapiens]                    82   7e-16

>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
          Length = 351

 Score =  698 bits (1801), Expect = 0.0
 Identities = 351/351 (100%), Positives = 351/351 (100%)

Query: 1   MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN 60
           MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN
Sbjct: 1   MVIMGQCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASN 60

Query: 61  RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA 120
           RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA
Sbjct: 61  RRFHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVA 120

Query: 121 TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR 180
           TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR
Sbjct: 121 TLLAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSR 180

Query: 181 MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV 240
           MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV
Sbjct: 181 MAPLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLV 240

Query: 241 KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA 300
           KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA
Sbjct: 241 KTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDA 300

Query: 301 EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL 351
           EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL
Sbjct: 301 EMRRTFRRLLCCACLRQSTRESVHYTSSAQGGASTRIMLPENGHPLMDSTL 351


>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  371 bits (953), Expect = e-103
 Identities = 176/307 (57%), Positives = 232/307 (75%), Gaps = 1/307 (0%)

Query: 6   QCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQ 65
           QC+YNE+I FFYN SGK L++ W     +V+ LG+TV + ++L NLLV+ AI  NRRFH 
Sbjct: 23  QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHF 82

Query: 66  PIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAI 125
           PIYYL+ NLAAAD FAG+AY +LMF+TGP T RL++  W LRQGL+DTSLTASVA LLAI
Sbjct: 83  PIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAI 142

Query: 126 AVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLL 185
           A+ERH +V  +QLH+R+   RVV++IV +W  A+ +G +P+  W+C+C ++ CS MAPL 
Sbjct: 143 AIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202

Query: 186 SRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVI 245
           S SYL  WA+ +L+ F++MV +Y  IF YVR+R  RM+ H S   R R+T +SL+KTVVI
Sbjct: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262

Query: 246 ILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRT 305
           +LGAF++CWTPG V+LLLD + C  C+VLA EK+FLLLAE NS +N  +YS RD EM  T
Sbjct: 263 VLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSAT 321

Query: 306 FRRLLCC 312
           FR++LCC
Sbjct: 322 FRQILCC 328


>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
          Length = 364

 Score =  371 bits (953), Expect = e-103
 Identities = 176/307 (57%), Positives = 232/307 (75%), Gaps = 1/307 (0%)

Query: 6   QCYYNETIGFFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQ 65
           QC+YNE+I FFYN SGK L++ W     +V+ LG+TV + ++L NLLV+ AI  NRRFH 
Sbjct: 23  QCFYNESIAFFYNRSGKHLATEWNTVSKLVMGLGITVCIFIMLANLLVMVAIYVNRRFHF 82

Query: 66  PIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAI 125
           PIYYL+ NLAAAD FAG+AY +LMF+TGP T RL++  W LRQGL+DTSLTASVA LLAI
Sbjct: 83  PIYYLMANLAAADFFAGLAYFYLMFNTGPNTRRLTVSTWLLRQGLIDTSLTASVANLLAI 142

Query: 126 AVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLL 185
           A+ERH +V  +QLH+R+   RVV++IV +W  A+ +G +P+  W+C+C ++ CS MAPL 
Sbjct: 143 AIERHITVFRMQLHTRMSNRRVVVVIVVIWTMAIVMGAIPSVGWNCICDIENCSNMAPLY 202

Query: 186 SRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVI 245
           S SYL  WA+ +L+ F++MV +Y  IF YVR+R  RM+ H S   R R+T +SL+KTVVI
Sbjct: 203 SDSYLVFWAIFNLVTFVVMVVLYAHIFGYVRQRTMRMSRHSSGPRRNRDTMMSLLKTVVI 262

Query: 246 ILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRT 305
           +LGAF++CWTPG V+LLLD + C  C+VLA EK+FLLLAE NS +N  +YS RD EM  T
Sbjct: 263 VLGAFIICWTPGLVLLLLD-VCCPQCDVLAYEKFFLLLAEFNSAMNPIIYSYRDKEMSAT 321

Query: 306 FRRLLCC 312
           FR++LCC
Sbjct: 322 FRQILCC 328


>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
          Length = 353

 Score =  331 bits (849), Expect = 5e-91
 Identities = 157/310 (50%), Positives = 217/310 (70%), Gaps = 1/310 (0%)

Query: 4   MGQCYYNETIGFFYNNSGKELSSHWR-PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRR 62
           M +C+Y++ + FFYN S  +    W   K V+V+ +G    + +  +N LVIAA+  NR+
Sbjct: 1   MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK 60

Query: 63  FHQPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATL 122
           FH P YYLL NLAAAD FAG+AY+FLMF+TGP +  L++  WFLRQGLLD+SLTAS+  L
Sbjct: 61  FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL 120

Query: 123 LAIAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMA 182
           L IAVERH S+M +++HS L + RV +LI+ VW  A+ +G +P   W+CLC +  CS +A
Sbjct: 121 LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA 180

Query: 183 PLLSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKT 242
           P+ SRSYL  W +S+L+ FL+MV VY RI+ YV+R+   ++ H S     R T + L+KT
Sbjct: 181 PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT 240

Query: 243 VVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEM 302
           V+ +LGAFVVCWTPG VVLLLDGL C  C V  V+++FLLLA  NS+VN  +YS +D +M
Sbjct: 241 VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM 300

Query: 303 RRTFRRLLCC 312
             T ++++CC
Sbjct: 301 YGTMKKMICC 310


>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
          Length = 382

 Score =  209 bits (533), Expect = 2e-54
 Identities = 115/304 (37%), Positives = 186/304 (61%), Gaps = 7/304 (2%)

Query: 17  YNNSGK-ELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLA 75
           YN +GK  +S+       +   + + +   ++L N+ V+  I   ++FH+P+YY +GNLA
Sbjct: 29  YNYTGKLNISADKENSIKLTSVVFILICCFIILENIFVLLTIWKTKKFHRPMYYFIGNLA 88

Query: 76  AADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMA 135
            +DL AGVAY   +  +G  T +L+   WFLR+G +  +L+ASV +LLAIA+ER+ +++ 
Sbjct: 89  LSDLLAGVAYTANLLLSGATTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLK 148

Query: 136 VQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWAL 195
           ++LH+     R+ +LI   WV +L LG LP   W+C+ AL  CS + PL  + Y+     
Sbjct: 149 MKLHNGSNNFRLFLLISACWVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTT 208

Query: 196 SSLLVFLLMVAVYTRIFFYVRRRVQRMA--EHVSCHPRYRETTLSLVKTVVIILGAFVVC 253
              L+ L +V +Y RI+  VR R +R+   +++S   R  E +L+L+KTV+I+L  F+ C
Sbjct: 209 VFTLLLLSIVILYCRIYSLVRTRSRRLTFRKNISKASRSSEKSLALLKTVIIVLSVFIAC 268

Query: 254 WTPGQVVLLLDGLGC--ESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLL- 310
           W P  ++LLLD +GC  ++C++L   +YFL+LA  NS  N  +Y+  + EMRR F R++ 
Sbjct: 269 WAPLFILLLLD-VGCKVKTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMS 327

Query: 311 CCAC 314
           CC C
Sbjct: 328 CCKC 331


>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
          Length = 378

 Score =  195 bits (495), Expect = 6e-50
 Identities = 109/311 (35%), Positives = 176/311 (56%), Gaps = 10/311 (3%)

Query: 10  NETIGFFYNNSGKELSSHWRPKD--VVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPI 67
           NET+   Y   GK         +   +   L L +   ++L NL+V+ AI  N +FH  +
Sbjct: 15  NETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRM 74

Query: 68  YYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAV 127
           Y+ +GNLA  DL AG+AY   +  +G +T  LS   WFLR+G +  +L AS  +LLAIA+
Sbjct: 75  YFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAI 134

Query: 128 ERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSR 187
           ERH +++ ++ +    R RV +LI   W+ A  LG LP   W+CL  L  CS + PL S+
Sbjct: 135 ERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSK 194

Query: 188 SYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIIL 247
            Y+A        + + +V +Y RI+F V+   +++A H        E +++L++TVVI++
Sbjct: 195 KYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANH-----NNSERSMALLRTVVIVV 249

Query: 248 GAFVVCWTPGQVVLLLDGLGC--ESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRT 305
             F+ CW+P  ++ L+D + C  ++C +L   ++F++LA  NS +N  +Y+    EMRR 
Sbjct: 250 SVFIACWSPLFILFLID-VACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRA 308

Query: 306 FRRLLCCACLR 316
           F RL+C   +R
Sbjct: 309 FFRLVCNCLVR 319


>gi|134244587 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 5 [Homo sapiens]
          Length = 353

 Score =  189 bits (479), Expect = 4e-48
 Identities = 117/325 (36%), Positives = 174/325 (53%), Gaps = 16/325 (4%)

Query: 17  YNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAA 76
           YN + + L +       V  A  + +   +++ NLLV+ A+A N +FH  +Y  LGNLAA
Sbjct: 18  YNYTKETLETQETTSRQVASAFIVILCCAIVVENLLVLIAVARNSKFHSAMYLFLGNLAA 77

Query: 77  ADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAV 136
           +DL AGVA++     +G  T RL+   WF R+G    +L+ASV +LLAIA+ERH ++  V
Sbjct: 78  SDLLAGVAFVANTLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKV 137

Query: 137 QLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALS 196
           +L+      R+++LI   W+ +L LG LP   W+CL  L+ CS + PL ++ Y+      
Sbjct: 138 KLYGSDKSCRMLLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTI 197

Query: 197 SLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTP 256
             ++ L +VA+Y RI+  VR     MA            TL+L+KTV I+LG F+VCW P
Sbjct: 198 FSIILLAIVALYVRIYCVVRSSHADMA---------APQTLALLKTVTIVLGVFIVCWLP 248

Query: 257 GQVVLLLD-GLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACL 315
              +LLLD      SC +L    YF  ++  NSL+N  +Y+ R  ++RR   R L C   
Sbjct: 249 AFSILLLDYACPVHSCPILYKAHYFFAVSTLNSLLNPVIYTWRSRDLRREVLRPLQC--- 305

Query: 316 RQSTRESVHYTSSAQGGASTRIMLP 340
               R  V      +GG     +LP
Sbjct: 306 ---WRPGVGVQGRRRGGTPGHHLLP 327


>gi|13540517 endothelial differentiation, sphingolipid
           G-protein-coupled receptor, 8 [Homo sapiens]
          Length = 398

 Score =  189 bits (479), Expect = 4e-48
 Identities = 123/346 (35%), Positives = 186/346 (53%), Gaps = 19/346 (5%)

Query: 10  NETIGFFYNNSGKELSSHWRP-----KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH 64
           +E I   YN +GK   + ++P      D VV    L V   ++L NL V+  +  + RFH
Sbjct: 12  SEVIVLHYNYTGKLRGARYQPGAGLRADAVVC---LAVCAFIVLENLAVLLVLGRHPRFH 68

Query: 65  QPIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLA 124
            P++ LLG+L  +DL AG AY   +  +GP T +LS   WF R+G +  +LTASV +LLA
Sbjct: 69  APMFLLLGSLTLSDLLAGAAYAANILLSGPLTLKLSPALWFAREGGVFVALTASVLSLLA 128

Query: 125 IAVERHRSVMAVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPL 184
           IA+ER  ++          RGR + +    W  +L LGLLPA  W+CL  LD CS + PL
Sbjct: 129 IALERSLTMARRGPAPVSSRGRTLAMAAAAWGVSLLLGLLPALGWNCLGRLDACSTVLPL 188

Query: 185 LSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRM------AEHVSCHPRYRETTLS 238
            +++Y+    L+ + +   + A+Y RI+  VR   +R+      A   S   R +  +L+
Sbjct: 189 YAKAYVLFCVLAFVGILAAICALYARIYCQVRANARRLPARPGTAGTTSTRARRKPRSLA 248

Query: 239 LVKTVVIILGAFVVCWTPGQVVLLLD-GLGCESCNVLAVEKYFLLLAEANSLVNAAVYSC 297
           L++T+ ++L AFV CW P  ++LLLD      +C VL     FL LA ANSL+N  +Y+ 
Sbjct: 249 LLRTLSVVLLAFVACWGPLFLLLLLDVACPARTCPVLLQADPFLGLAMANSLLNPIIYTL 308

Query: 298 RDAEMRRTFRRLLCC---ACLRQSTRESVHYTSSAQGGASTRIMLP 340
            + ++R    RL+CC   +C R  +  S    S+A+     R  LP
Sbjct: 309 TNRDLRHALLRLVCCGRHSCGRDPS-GSQQSASAAEASGGLRRCLP 353


>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
           sapiens]
          Length = 384

 Score =  181 bits (460), Expect = 7e-46
 Identities = 129/336 (38%), Positives = 181/336 (53%), Gaps = 15/336 (4%)

Query: 9   YNETIGFFYNNSGKELSSHWRPKDVVVVAL-GLTV--SVLVLLTNLLVIAAIASNRRFHQ 65
           ++  I   YN+SG+ L+    P+D  + AL GL+V  S LV+L NLLV+AAI S+ R  +
Sbjct: 21  HSRLIVLHYNHSGR-LAGRGGPEDGGLGALRGLSVAASCLVVLENLLVLAAITSHMRSRR 79

Query: 66  PIYYLLGNLAAADLFAGVAYLFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAI 125
            +YY L N+  +DL  G AYL  +  +G RT RL+   WFLR+GLL T+L AS  +LL  
Sbjct: 80  WVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFLREGLLFTALAASTFSLLFT 139

Query: 126 AVERHRSVMAVQLHSRLPRGRVVMLIVGV-WVAALGLGLLPAHSWHCLCALDRCSRMAPL 184
           A ER  +++     S   +   V   +G+ W+ A  LG+LP   W+CLCA DRCS + PL
Sbjct: 140 AGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPL 199

Query: 185 LSRSYLAVWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVV 244
            S+ Y+    L  L++F  ++A    ++  + R VQ   +     P  R     L+KTV+
Sbjct: 200 YSKRYI----LFCLVIFAGVLATIMGLYGAIFRLVQASGQKAP-RPAARRKARRLLKTVL 254

Query: 245 IILGAFVVCWTPGQVVLLLDGLGCE--SCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEM 302
           +IL AF+VCW P   +LL D  G    +   L    + L LA  NS VN  +YS R  E+
Sbjct: 255 MILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNSAVNPIIYSFRSREV 314

Query: 303 RRTFRRLLCCACLRQSTR---ESVHYTSSAQGGAST 335
            R     LCC CLR   R   + +     A  GAST
Sbjct: 315 CRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGAST 350


>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
          Length = 330

 Score =  134 bits (336), Expect = 2e-31
 Identities = 96/285 (33%), Positives = 149/285 (52%), Gaps = 18/285 (6%)

Query: 32  DVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFH 91
           DVV+   G  VS      N LV+A I     F  P++ L+G+LA ADL AG+    L+ H
Sbjct: 44  DVVLCISGTLVSC----ENALVVAIIVGTPAFRAPMFLLVGSLAVADLLAGLG---LVLH 96

Query: 92  TGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRVVML 150
                   S E   +  G+L  + TAS+ +LLAI V+R+ S+  A+  +S     R  ++
Sbjct: 97  FAAVFCIGSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTRTYVM 156

Query: 151 IVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTR 210
           +  VW  ALGLGLLP  +W+CL  L  C  + P LS+++L V A++  +VF +M+ +Y +
Sbjct: 157 LALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHLVVLAIAFFMVFGIMLQLYAQ 215

Query: 211 IFFYVRRRVQRMA--EHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGC 268
           I   V R  Q++A   H+     Y  T    + T+ ++LGAF  CW P  V  LL     
Sbjct: 216 ICRIVCRHAQQIALQRHLLPASHYVATRKG-IATLAVVLGAFAACWLPFTVYCLLG---- 270

Query: 269 ESCNVLAVEKYFLLL-AEANSLVNAAVYSCRDAEMRRTFRRLLCC 312
              +   +  Y  LL A  NS++N  +Y+ R+ ++++    + CC
Sbjct: 271 -DAHSPPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWAVCCC 314


>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
          Length = 362

 Score =  127 bits (319), Expect = 1e-29
 Identities = 98/286 (34%), Positives = 148/286 (51%), Gaps = 18/286 (6%)

Query: 30  PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAY-LFL 88
           P DV++   G  ++      N LV+A IAS      P++ L+G+LA ADL AG    L  
Sbjct: 74  PWDVLLCVSGTVIAG----ENALVVALIASTPALRTPMFVLVGSLATADLLAGCGLILHF 129

Query: 89  MFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRV 147
           +F     +  +SL    L  G L  S  ASV++LLAI V+R+ S+  A+  +SR     V
Sbjct: 130 VFQYLVPSETVSL----LTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGV 185

Query: 148 VMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAV 207
            +L+   W  +LGLGLLP   W+CL     CS + P L+RS++A+ + +  +VF +M+ +
Sbjct: 186 HLLLAATWTVSLGLGLLPVLGWNCLAERAACSVVRP-LARSHVALLSAAFFMVFGIMLHL 244

Query: 208 YTRIFFYVRRRVQRMAEHVSC-HPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGL 266
           Y RI   V R   ++A    C  P +   T   V T+ ++LG F   W P  +  ++   
Sbjct: 245 YVRICQVVWRHAHQIALQQHCLAPPHLAATRKGVGTLAVVLGTFGASWLPFAIYCVVG-- 302

Query: 267 GCESCNVLAVEKYFLLL-AEANSLVNAAVYSCRDAEMRRTFRRLLC 311
              S    AV  Y  LL A  NS++N  +Y+ R+ E++R    LLC
Sbjct: 303 ---SHEDPAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLC 345


>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
          Length = 334

 Score =  127 bits (318), Expect = 2e-29
 Identities = 92/295 (31%), Positives = 149/295 (50%), Gaps = 23/295 (7%)

Query: 30  PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA----Y 85
           P D+V+   G  +S      N +V+  I  N     P++ L+G+LA ADL AG+     +
Sbjct: 46  PWDIVLCTSGTLISC----ENAIVVLIIFHNPSLRAPMFLLIGSLALADLLAGIGLITNF 101

Query: 86  LFLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSV-MAVQLHSRLPR 144
           +F        T  +++       GL+  S +ASV +LLAI V+R+ S+  A+  HS    
Sbjct: 102 VFAYLLQSEATKLVTI-------GLIVASFSASVCSLLAITVDRYLSLYYALTYHSERTV 154

Query: 145 GRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLM 204
               +++V +W  ++ LGLLP   W+CL     CS + P L+++  A+ ++S L +F LM
Sbjct: 155 TFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRP-LTKNNAAILSVSFLFMFALM 213

Query: 205 VAVYTRIFFYVRRRVQRMA-EHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLL 263
           + +Y +I   V R   ++A +H      +  TT   V T+ IILG F  CW P  +  L+
Sbjct: 214 LQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKGVSTLAIILGTFAACWMPFTLYSLI 273

Query: 264 DGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQS 318
                 S    A     LL A  NS++N  +Y+ R+ E+++    L+CC C+  S
Sbjct: 274 ADYTYPSIYTYAT----LLPATYNSIINPVIYAFRNQEIQKAL-CLICCGCIPSS 323


>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
          Length = 472

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411


>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
          Length = 439

 Score =  117 bits (292), Expect = 2e-26
 Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
           + + +  L LT+    +L NLLV+  I  +R    +P Y+ +G+LA ADL   V   Y F
Sbjct: 82  QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 141

Query: 88  LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
           + FH   R  + S   +  + G +  S TASV +L   A++R+ S+     + R+  R +
Sbjct: 142 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 199

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
            V+    +W  A+ + +LP   W+C      CS + P +  +YL  W   + ++ L +V 
Sbjct: 200 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 259

Query: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
            Y  I +       RM +         H S         P      + L KT+V+IL   
Sbjct: 260 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 319

Query: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           ++CW P   +++ D  G  +  +  V  +  +L   NS VN  +Y+ R  ++R  FR +
Sbjct: 320 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 378


>gi|5174535 melanocortin 5 receptor [Homo sapiens]
          Length = 325

 Score =  114 bits (285), Expect = 1e-25
 Identities = 83/302 (27%), Positives = 145/302 (48%), Gaps = 42/302 (13%)

Query: 34  VVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA------YLF 87
           + V + LT+ V+ LL N+LVI AI  N+  H P+Y+ + +LA AD+   ++       ++
Sbjct: 38  IAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIY 97

Query: 88  LMFHTGPRTARLSLEGWFLR------QGLLDTSLTASVATLLAIAVERHRSVM-AVQLHS 140
           L+         L +   F+R        ++  S+ AS+ +LLAIAV+R+ ++  A++ H 
Sbjct: 98  LL-----NNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHH 152

Query: 141 RLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLL- 199
            +   R   +I G+W    G G+                 +  L S S   +  L S+  
Sbjct: 153 IMTARRSGAIIAGIWAFCTGCGI-----------------VFILYSESTYVILCLISMFF 195

Query: 200 -VFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQ 258
            +  L+V++Y  +F   R  V+R+A         + T++    TV ++LG F VCW P  
Sbjct: 196 AMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFF 255

Query: 259 VVLLLDGLGCES----CNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCAC 314
           + L L  L C         ++    +L+L   NS+++  +Y+ R  EMR+TF+ ++CC  
Sbjct: 256 LHLTL-MLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRG 314

Query: 315 LR 316
            R
Sbjct: 315 FR 316


>gi|119508433 melanocortin 4 receptor [Homo sapiens]
          Length = 332

 Score =  105 bits (262), Expect = 6e-23
 Identities = 74/284 (26%), Positives = 142/284 (50%), Gaps = 27/284 (9%)

Query: 40  LTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVA------YLFLMFHTG 93
           +T+ V+ LL N+LVI AIA N+  H P+Y+ + +LA AD+   V+       + L+  T 
Sbjct: 52  VTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTD 111

Query: 94  PRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVM-AVQLHSRLPRGRVVMLIV 152
                 ++    +   ++ +SL AS+ +LL+IAV+R+ ++  A+Q H+ +   RV ++I 
Sbjct: 112 TDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIIS 171

Query: 153 GVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVAVYTRIF 212
            +W A    G+L       +   D  + +  L++  +          +  LM ++Y  +F
Sbjct: 172 CIWAACTVSGIL------FIIYSDSSAVIICLITMFF---------TMLALMASLYVHMF 216

Query: 213 FYVRRRVQRMAEHVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLDGLGCES-- 270
              R  ++R+A         +   +    T+ I++G FVVCW P  + L+   + C    
Sbjct: 217 LMARLHIKRIAVLPGTGAIRQGANMKGAITLTILIGVFVVCWAPFFLHLIF-YISCPQNP 275

Query: 271 --CNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCC 312
                ++    +L+L   NS+++  +Y+ R  E+R+TF+ ++CC
Sbjct: 276 YCVCFMSHFNLYLILIMCNSIIDPLIYALRSQELRKTFKEIICC 319


>gi|170671732 melanocortin 3 receptor [Homo sapiens]
          Length = 323

 Score =  105 bits (261), Expect = 8e-23
 Identities = 88/314 (28%), Positives = 148/314 (47%), Gaps = 40/314 (12%)

Query: 15  FFYNNSGKELSSHWRPKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNL 74
           FF N S          K  V ++LG    ++ LL N+LVI A+  N   H P+Y+ L +L
Sbjct: 25  FFSNQSSSAFCEQVFIKPEVFLSLG----IVSLLENILVILAVVRNGNLHSPMYFFLCSL 80

Query: 75  AAADLFAGVA-YLFLMFHTGPRTARLSLEGWFLR------QGLLDTSLTASVATLLAIAV 127
           A AD+   V+  L  +      +  L+ E  F++        ++  SL AS+  LLAIAV
Sbjct: 81  AVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAV 140

Query: 128 ERHRSVM-AVQLHSRLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLS 186
           +R+ ++  A++ HS +   + + LIV +WV                C +  C  +  + S
Sbjct: 141 DRYVTIFYALRYHSIMTVRKALTLIVAIWVC---------------CGV--CGVVFIVYS 183

Query: 187 RSYLAVWALSSLL--VFLLMVAVYTRIFFYVRRRVQRMAEHVSCH--PRYRETTLSLVKT 242
            S + +  L ++   + LLM  +Y  +F + R  V+R+A           + + +    T
Sbjct: 184 ESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVT 243

Query: 243 VVIILGAFVVCWTPGQVVLLLDGLGCES-----CNVLAVEKYFLLLAEANSLVNAAVYSC 297
           + I+LG F+ CW P  + L+L  + C +     C       Y L+L   NS+++  +Y+ 
Sbjct: 244 ITILLGVFIFCWAPFFLHLVLI-ITCPTNPYCICYTAHFNTY-LVLIMCNSVIDPLIYAF 301

Query: 298 RDAEMRRTFRRLLC 311
           R  E+R TFR +LC
Sbjct: 302 RSLELRNTFREILC 315


>gi|5921992 adenosine A2a receptor [Homo sapiens]
          Length = 412

 Score =  100 bits (250), Expect = 1e-21
 Identities = 94/340 (27%), Positives = 152/340 (44%), Gaps = 33/340 (9%)

Query: 34  VVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYL--FLMFH 91
           V + + L ++VL +L N+LV  A+  N        Y + +LAAAD+  GV  +   +   
Sbjct: 8   VYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAIPFAITIS 67

Query: 92  TGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPRG-RVVML 150
           TG   A     G       +     +S+ +LLAIA++R+ ++     ++ L  G R   +
Sbjct: 68  TGFCAA---CHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTRAKGI 124

Query: 151 IVGVWVAALGLGLLPAHSWH--------------CLCALDRC--SRMAPLLSRSYLAVWA 194
           I   WV +  +GL P   W+              C      C    + P+    Y   +A
Sbjct: 125 IAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYFNFFA 184

Query: 195 LSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRET---TLSLVKTVVIILGAFV 251
              L+  LLM+ VY RIF   RR++++M        R R T    +   K++ II+G F 
Sbjct: 185 -CVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVGLFA 243

Query: 252 VCWTPGQVVLLLDGLGCESCNVLAVEKYFL--LLAEANSLVNAAVYSCRDAEMRRTFRRL 309
           +CW P  ++       C  C+   +   +L  +L+  NS+VN  +Y+ R  E R+TFR++
Sbjct: 244 LCWLPLHIINCFT-FFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFRKI 302

Query: 310 LCCACLRQSTRESVHYTS----SAQGGASTRIMLPENGHP 345
           +    LRQ        TS    +A G    ++ L  NGHP
Sbjct: 303 IRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHP 342


>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
          Length = 360

 Score = 95.9 bits (237), Expect = 5e-20
 Identities = 82/321 (25%), Positives = 141/321 (43%), Gaps = 18/321 (5%)

Query: 30  PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQ-PIYYLLGNLAAADLFAGVAYL-- 86
           P+   V  L   + +L  L N+ V+  I S+ +  + P Y  +G+LA AD  A V +   
Sbjct: 31  PQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLASVVFACS 90

Query: 87  FLMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRG 145
           F+ FH        ++  + L+ G +  + TASV +LL  A++R+  +     +  L  RG
Sbjct: 91  FVNFHVFHGVDSKAV--FLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKALLTRG 148

Query: 146 RVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMV 205
           R ++ +  +WV +  +  LP   W C C    CS + PL+   YL  W L    +F  ++
Sbjct: 149 RALVTLGIMWVLSALVSYLPLMGWTC-CPRP-CSELFPLIPNDYLLSWLLFIAFLFSGII 206

Query: 206 AVYTRIFFYVRRRVQRMAEH----VSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVL 261
             Y  + +   + V  ++ H    V    R R   + L KT+ ++L   ++CW P   ++
Sbjct: 207 YTYGHVLWKAHQHVASLSGHQDRQVPGMARMR-LDVRLAKTLGLVLAVLLICWFPVLALM 265

Query: 262 LLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLL-----CCACLR 316
                   S  V     +  +L   NS+VN  +Y+ R  E+R +    L     C   L 
Sbjct: 266 AHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIRSSAHHCLAHWKKCVRGLG 325

Query: 317 QSTRESVHYTSSAQGGASTRI 337
              +E    +S  +  A  +I
Sbjct: 326 SEAKEEAPRSSVTETEADGKI 346


>gi|115305569 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 78/303 (25%), Positives = 141/303 (46%), Gaps = 42/303 (13%)

Query: 36  VALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAG--VAYLFLMFHTG 93
           + + + ++++ +  N+LVI A+  N+      +  + +LA AD+  G  V  L ++ + G
Sbjct: 13  IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72

Query: 94  PRT-----ARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL--PRGR 146
           P+T       ++     L Q        +S+  LLAIAV+R+  V     +  +  PR R
Sbjct: 73  PQTYFHTCLMVACPVLILTQ--------SSILALLAIAVDRYLRVKIPLRYKMVVTPR-R 123

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRC-------------SRMAPLLSRSYLA-- 191
             + I G W+ +  +GL P   W+ L A++R                   ++S  Y+   
Sbjct: 124 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183

Query: 192 ---VWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHP-RYRETTLSLVKTVVIIL 247
              VW L  L   LLMV +Y  +F+ +R+++ +     S  P +Y    L + K++ +IL
Sbjct: 184 NFFVWVLPPL---LLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240

Query: 248 GAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYF-LLLAEANSLVNAAVYSCRDAEMRRTF 306
             F + W P  ++  +  L C SC+  ++  Y  + L   NS +N  VY+ R  + R TF
Sbjct: 241 FLFALSWLPLHILNCIT-LFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299

Query: 307 RRL 309
            ++
Sbjct: 300 LKI 302


>gi|4501947 adenosine A1 receptor [Homo sapiens]
          Length = 326

 Score = 90.9 bits (224), Expect = 2e-18
 Identities = 78/303 (25%), Positives = 141/303 (46%), Gaps = 42/303 (13%)

Query: 36  VALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAG--VAYLFLMFHTG 93
           + + + ++++ +  N+LVI A+  N+      +  + +LA AD+  G  V  L ++ + G
Sbjct: 13  IGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIG 72

Query: 94  PRT-----ARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL--PRGR 146
           P+T       ++     L Q        +S+  LLAIAV+R+  V     +  +  PR R
Sbjct: 73  PQTYFHTCLMVACPVLILTQ--------SSILALLAIAVDRYLRVKIPLRYKMVVTPR-R 123

Query: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRC-------------SRMAPLLSRSYLA-- 191
             + I G W+ +  +GL P   W+ L A++R                   ++S  Y+   
Sbjct: 124 AAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYMVYF 183

Query: 192 ---VWALSSLLVFLLMVAVYTRIFFYVRRRVQRMAEHVSCHP-RYRETTLSLVKTVVIIL 247
              VW L  L   LLMV +Y  +F+ +R+++ +     S  P +Y    L + K++ +IL
Sbjct: 184 NFFVWVLPPL---LLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL 240

Query: 248 GAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYF-LLLAEANSLVNAAVYSCRDAEMRRTF 306
             F + W P  ++  +  L C SC+  ++  Y  + L   NS +N  VY+ R  + R TF
Sbjct: 241 FLFALSWLPLHILNCIT-LFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTF 299

Query: 307 RRL 309
            ++
Sbjct: 300 LKI 302


>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
           sapiens]
          Length = 390

 Score = 89.7 bits (221), Expect = 3e-18
 Identities = 83/350 (23%), Positives = 146/350 (41%), Gaps = 73/350 (20%)

Query: 30  PKDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLM 89
           P  V++V L   +++   L+N  VIA +   R+ H P  YL+ +LA  DL   +  +   
Sbjct: 47  PWKVLLVMLLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVM--- 103

Query: 90  FHTGPRTARLSLEG-WFLRQGLLD-------TSLTASVATLLAIAVERHRSVM-AVQLHS 140
               P +   ++ G W L Q + D       T  TAS+  L  IA++R+ ++  AV+  +
Sbjct: 104 ----PISTMYTVTGRWTLGQVVCDFWLSSDITCCTASILHLCVIALDRYWAITDAVEYSA 159

Query: 141 RLPRGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLV 200
           +    R  ++I  VWV ++ +  LP   W    A +  S            V++      
Sbjct: 160 KRTPKRAAVMIALVWVFSISIS-LPPFFWRQAKAEEEVSECVVNTDHILYTVYSTVGAFY 218

Query: 201 F--LLMVAVYTRIFFYVRRRVQRM-----------AEHVSCHPRYRETTLSL-------- 239
           F  LL++A+Y RI+   R R+ +            A+ ++  P    +  S+        
Sbjct: 219 FPTLLLIALYGRIYVEARSRILKQTPNRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVP 278

Query: 240 ----------------------------------VKTVVIILGAFVVCWTPGQVVLLLDG 265
                                              KT+ IILGAF+VCW P  ++ L+  
Sbjct: 279 SESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMP 338

Query: 266 LGCESCNV-LAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCAC 314
           +  ++C   LA+  +F  L   NSL+N  +Y+  + + ++ F +L+   C
Sbjct: 339 ICKDACWFHLAIFDFFTWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKC 388


>gi|4501951 adenosine A2b receptor [Homo sapiens]
          Length = 332

 Score = 88.2 bits (217), Expect = 1e-17
 Identities = 83/327 (25%), Positives = 145/327 (44%), Gaps = 50/327 (15%)

Query: 31  KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMF 90
           +D + VAL L ++ L +  N+LV AA+ +      P  Y L +LAAAD+  G+  +    
Sbjct: 6   QDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFAI---- 61

Query: 91  HTGPRTARLSL------EGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRLPR 144
              P    +SL       G       +     +S+ +LLA+AV+R+ ++     +  L  
Sbjct: 62  ---PFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVT 118

Query: 145 G-RVVMLIVGVWVAALGLGLLPAHSWHC------------------LCALDRCSRMAPLL 185
           G R   +I  +WV A G+GL P   W+                    C L +C     ++
Sbjct: 119 GTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKC-LFENVV 177

Query: 186 SRSYLAVWALSSLLV--FLLMVAVYTRIFFYVRRRVQRMAEHVSCHPRYRETTLSLVKTV 243
             SY+  +     ++   L+M+ +Y +IF    R++QR  E +       +  +   K++
Sbjct: 178 PMSYMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQR-TELMDHSRTTLQREIHAAKSL 236

Query: 244 VIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEK--------YFLLLAEANSLVNAAVY 295
            +I+G F +CW P      +  + C +    A  K          +LL+ ANS+VN  VY
Sbjct: 237 AMIVGIFALCWLP------VHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVY 290

Query: 296 SCRDAEMRRTFRRLLCCACLRQSTRES 322
           + R+ + R TF +++    L Q+  +S
Sbjct: 291 AYRNRDFRYTFHKIISRYLLCQADVKS 317


>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
          Length = 520

 Score = 87.8 bits (216), Expect = 1e-17
 Identities = 85/337 (25%), Positives = 142/337 (42%), Gaps = 61/337 (18%)

Query: 36  VALGLTVSVLVLLT---NLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFLMFHT 92
           +++GL +   +L     N+LVI ++A NR    P  Y + NLA AD       L L F  
Sbjct: 46  ISVGLVLGAFILFAIVGNILVILSVACNRHLRTPTNYFIVNLAMAD-------LLLSFTV 98

Query: 93  GPRTARLSLEG-WFLRQGLLD-------TSLTASVATLLAIAVERHRSV-MAVQLHSRLP 143
            P +A L + G W L +   D          TAS+ +L AI+++R+  V  ++Q  + + 
Sbjct: 99  LPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVT 158

Query: 144 RGRVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVW-ALSSLLVFL 202
           R + ++ ++ VWV +  + + P   W      D   +   +    + A++ +L S  + L
Sbjct: 159 RRKAILALLSVWVLSTVISIGPLLGWKEPAPND--DKECGVTEEPFYALFSSLGSFYIPL 216

Query: 203 LMVAV-YTRIFFYVRRRVQRMAEHV------------SCHPR-YRETTLS---------- 238
            ++ V Y R++   +R  + +   V              H + + E TLS          
Sbjct: 217 AVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPR 276

Query: 239 ---------------LVKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLL 283
                            KT+ I++G F++CW P  + L L  L        AV K    L
Sbjct: 277 SSIAVKLFKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTLKPPDAVFKVVFWL 336

Query: 284 AEANSLVNAAVYSCRDAEMRRTFRRLLCCACLRQSTR 320
              NS +N  +Y C   E +R F R+L C C  +  R
Sbjct: 337 GYFNSCLNPIIYPCSSKEFKRAFVRILGCQCRGRGRR 373


>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
          Length = 413

 Score = 83.2 bits (204), Expect = 3e-16
 Identities = 92/342 (26%), Positives = 161/342 (47%), Gaps = 55/342 (16%)

Query: 32  DVVVVALGLTVSVLVLLT---NLLVIAAIASNRRFHQPIYYLLGNLAAADLFAGVAYLFL 88
           +V VV +G+ +S++VL     N+LVI AIA   R      Y + +LA ADL  G+A +  
Sbjct: 30  EVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF 89

Query: 89  MFHTGPRTARLSLEGWFLRQGLLD--TSL-----TASVATLLAIAVERHRSVMA-VQLHS 140
                   A + ++ W       +  TS+     TAS+ TL  IAV+R+ ++ +  +  S
Sbjct: 90  ------GAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQS 143

Query: 141 RLPRGRVVMLIVGVWVAALGLGLLPAH-SWHCLCALDRCSRMAPLLSRSYLA--VWALSS 197
            L + +  ++I+ VW+ +     LP    W+     +  +  A      +     +A++S
Sbjct: 144 LLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIAS 203

Query: 198 LLV-----FLLMVAVYTRIFFYVRRRVQRMAE-----HV-----------SCHPRYRETT 236
            +V      ++MV VY+R+F   +R++Q++ +     HV           + H   R + 
Sbjct: 204 SIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSK 263

Query: 237 LSL-----VKTVVIILGAFVVCWTPGQVVLLLDGLGCESCNVLAVEKYFLL--LAEANSL 289
             L     +KT+ II+G F +CW P  +V ++  +     N++  E Y LL  +   NS 
Sbjct: 264 FCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI---QDNLIRKEVYILLNWIGYVNSG 320

Query: 290 VNAAVYSCRDAEMRRTFRRLLCCACLRQSTRESVHYTSSAQG 331
            N  +Y CR  + R  F+ LL   CLR+S+ ++     S+ G
Sbjct: 321 FNPLIY-CRSPDFRIAFQELL---CLRRSSLKAYGNGYSSNG 358


>gi|193083134 melanocortin 1 receptor [Homo sapiens]
          Length = 317

 Score = 82.0 bits (201), Expect = 7e-16
 Identities = 81/292 (27%), Positives = 138/292 (47%), Gaps = 35/292 (11%)

Query: 38  LGLTVSVLVLLTNLLVIAAIASNRRFHQPIYYLLGNLAAADLFAG-----VAYLFLMFHT 92
           L L++ ++ L+ N LV+A IA NR  H P+Y  +  LA +DL           + L+   
Sbjct: 44  LFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEA 103

Query: 93  GPRTARLSLEGWFLRQ--GLLD----TSLTASVATLLAIAVERHRSVM-AVQLHSRLPRG 145
           G   AR ++    L+Q   ++D    +S+ +S+  L AIAV+R+ S+  A++ HS +   
Sbjct: 104 GALVARAAV----LQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLP 159

Query: 146 RVVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMV 205
           R    +  +WVA++    L          +     +A LL    L V+ L+ L   +LM 
Sbjct: 160 RARRAVAAIWVASVVFSTL---------FIAYYDHVAVLLC---LVVFFLAML---VLMA 204

Query: 206 AVYTRIFFYVRRRVQRMAE-HVSCHPRYRETTLSLVKTVVIILGAFVVCWTPGQVVLLLD 264
            +Y  +     +  Q +A  H    P ++   L    T+ I+LG F +CW P  + L L 
Sbjct: 205 VLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLI 264

Query: 265 GLGCE--SCNVLAVE-KYFLLLAEANSLVNAAVYSCRDAEMRRTFRRLLCCA 313
            L  E  +C  +      FL L   N++++  +Y+    E+RRT + +L C+
Sbjct: 265 VLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCS 316


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.329    0.138    0.429 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,362,280
Number of Sequences: 37866
Number of extensions: 420350
Number of successful extensions: 2369
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 390
Number of HSP's successfully gapped in prelim test: 185
Number of HSP's that attempted gapping in prelim test: 1533
Number of HSP's gapped (non-prelim): 746
length of query: 351
length of database: 18,247,518
effective HSP length: 103
effective length of query: 248
effective length of database: 14,347,320
effective search space: 3558135360
effective search space used: 3558135360
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.9 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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