Guide to the Human Genome
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Name: MC1R Sequence: fasta or formatted (317aa) NCBI GI: 193083134
Description:

melanocortin 1 receptor

Referenced in:

Peptide and Protein G-coupled Signals
Skin and Related Tissues

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            11.0         35           2
 C cysteine            4.4         14           2
 D aspartate           2.2          7           1
 E glutamate           2.2          7           1
 F phenylalanine       5.4         17           2
 G glycine             5.0         16           1
 H histidine           3.2         10           1
 I isoleucine          7.3         23           2
 K lysine              1.6          5           1
 L leucine            17.4         55           3
 M methionine          1.9          6           1
 N asparagine          3.2         10           1
 P proline             2.8          9           1
 Q glutamine           3.5         11           2
 R arginine            5.0         16           2
 S serine              6.6         21           2
 T threonine           4.4         14           1
 V valine              9.5         30           2
 W tryptophan          0.9          3           1
 Y tyrosine            2.5          8           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   melanocortin 1 receptor 
MC4R                  0.447   melanocortin 4 receptor 
MC3R                  0.436   melanocortin 3 receptor 
MC5R                  0.417   melanocortin 5 receptor 
MC2R                  0.331   melanocortin 2 receptor 
GPR12                 0.139   G protein-coupled receptor 12 
ADRA1A                0.129   alpha-1A-adrenergic receptor isoform 4 
ADRA1A                0.129   alpha-1A-adrenergic receptor isoform 1 
ADRA1A                0.129   alpha-1A-adrenergic receptor isoform 2 
ADRA1A                0.129   alpha-1A-adrenergic receptor isoform 3 
S1PR1                 0.124   sphingosine-1-phosphate receptor 1 
S1PR2                 0.124   endothelial differentiation, sphingolipid G-protein...
GPR6                  0.122   G protein-coupled receptor 6 
GPR3                  0.120   G protein-coupled receptor 3 
ADRA1D                0.112   alpha-1D-adrenergic receptor 
LPAR1                 0.107   lysophosphatidic acid receptor 1 
LPAR1                 0.107   lysophosphatidic acid receptor 1 
ADRA1B                0.105   alpha-1B-adrenergic receptor 
CNR1                  0.098   cannabinoid receptor 1 isoform a 
CNR1                  0.098   cannabinoid receptor 1 isoform a 
CNR1                  0.098   cannabinoid receptor 1 isoform a 
CNR1                  0.098   cannabinoid receptor 1 isoform a 
CNR1                  0.098   cannabinoid receptor 1 isoform a 
CNR1                  0.098   cannabinoid receptor 1 isoform b 
ADORA1                0.095   adenosine A1 receptor 
ADORA1                0.095   adenosine A1 receptor 
LPAR2                 0.095   lysophosphatidic acid receptor 2 
S1PR5                 0.088   endothelial differentiation, sphingolipid G-protein-...
TAAR5                 0.087   trace amine associated receptor 5 
LPAR3                 0.083   lysophosphatidic acid receptor 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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