Guide to the Human Genome
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Name: MC4R Sequence: fasta or formatted (332aa) NCBI GI: 119508433
Description:

melanocortin 4 receptor

Referenced in:

Epidermal Growth Factor
Peptide and Protein G-coupled Signals

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.3         21           2
 C cysteine            4.5         15           2
 D aspartate           3.0         10           1
 E glutamate           2.1          7           1
 F phenylalanine       5.4         18           2
 G glycine             4.8         16           2
 H histidine           3.0         10           1
 I isoleucine         11.7         39           3
 K lysine              2.4          8           1
 L leucine            12.0         40           2
 M methionine          3.9         13           1
 N asparagine          4.5         15           1
 P proline             2.4          8           1
 Q glutamine           1.8          6           1
 R arginine            3.3         11           1
 S serine             10.5         35           2
 T threonine           5.1         17           1
 V valine              7.5         25           2
 W tryptophan          0.9          3           1
 Y tyrosine            4.5         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   melanocortin 4 receptor 
MC5R                  0.574   melanocortin 5 receptor 
MC3R                  0.559   melanocortin 3 receptor 
MC1R                  0.419   melanocortin 1 receptor 
MC2R                  0.396   melanocortin 2 receptor 
LPAR1                 0.163   lysophosphatidic acid receptor 1 
LPAR1                 0.163   lysophosphatidic acid receptor 1 
GPR12                 0.153   G protein-coupled receptor 12 
S1PR1                 0.150   sphingosine-1-phosphate receptor 1 
GPR3                  0.141   G protein-coupled receptor 3 
LPAR3                 0.139   lysophosphatidic acid receptor 3 
S1PR2                 0.135   endothelial differentiation, sphingolipid G-protein...
S1PR3                 0.130   sphingosine-1-phosphate receptor 3 
LPAR2                 0.125   lysophosphatidic acid receptor 2 
ADORA2A               0.121   adenosine A2a receptor 
S1PR5                 0.114   endothelial differentiation, sphingolipid G-protein-...
GPR6                  0.111   G protein-coupled receptor 6 
ADRA1A                0.111   alpha-1A-adrenergic receptor isoform 4 
ADRA1A                0.111   alpha-1A-adrenergic receptor isoform 1 
ADRA1A                0.111   alpha-1A-adrenergic receptor isoform 2 
ADRA1A                0.111   alpha-1A-adrenergic receptor isoform 3 
CNR1                  0.108   cannabinoid receptor 1 isoform a 
CNR1                  0.108   cannabinoid receptor 1 isoform a 
CNR1                  0.108   cannabinoid receptor 1 isoform a 
CNR1                  0.108   cannabinoid receptor 1 isoform a 
CNR1                  0.108   cannabinoid receptor 1 isoform a 
CNR1                  0.108   cannabinoid receptor 1 isoform b 
ADORA3                0.103   adenosine A3 receptor isoform 2 
ADRA1B                0.100   alpha-1B-adrenergic receptor 
ADRB2                 0.094   adrenergic, beta-2-, receptor, surface 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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