Guide to the Human Genome
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Name: HTR1B Sequence: fasta or formatted (390aa) NCBI GI: 4504533
Description:

5-hydroxytryptamine (serotonin) receptor 1B

Referenced in:

Common Drug Targets
Serotonin
DNA Transposon and Retrovirus-related Sequences

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.0         35           2
 C cysteine            2.8         11           2
 D aspartate           3.6         14           1
 E glutamate           3.3         13           3
 F phenylalanine       4.4         17           2
 G glycine             3.1         12           1
 H histidine           1.3          5           1
 I isoleucine          7.9         31           2
 K lysine              4.6         18           3
 L leucine            10.8         42           3
 M methionine          2.1          8           1
 N asparagine          2.8         11           1
 P proline             5.6         22           4
 Q glutamine           2.6         10           1
 R arginine            4.6         18           1
 S serine              9.0         35           2
 T threonine           7.9         31           2
 V valine              8.2         32           2
 W tryptophan          2.6         10           1
 Y tyrosine            3.8         15           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   5-hydroxytryptamine (serotonin) receptor 1B 
HTR1D                 0.590   5-hydroxytryptamine (serotonin) receptor 1D 
HTR1F                 0.412   5-hydroxytryptamine (serotonin) receptor 1F 
HTR1E                 0.385   5-hydroxytryptamine (serotonin) receptor 1E 
HTR1A                 0.359   5-hydroxytryptamine (serotonin) receptor 1A 
ADRA1A                0.255   alpha-1A-adrenergic receptor isoform 4 
ADRA1A                0.255   alpha-1A-adrenergic receptor isoform 1 
ADRA1A                0.255   alpha-1A-adrenergic receptor isoform 2 
ADRA1A                0.255   alpha-1A-adrenergic receptor isoform 3 
HTR7                  0.251   5-hydroxytryptamine receptor 7 isoform b 
HTR7                  0.251   5-hydroxytryptamine receptor 7 isoform d 
HTR7                  0.251   5-hydroxytryptamine receptor 7 isoform a 
HTR5A                 0.249   5-hydroxytryptamine receptor 5A 
ADRA1B                0.240   alpha-1B-adrenergic receptor 
DRD1                  0.236   dopamine receptor D1 
ADRA1D                0.235   alpha-1D-adrenergic receptor 
DRD2                  0.226   dopamine receptor D2 isoform short 
ADRB1                 0.223   beta-1-adrenergic receptor 
DRD3                  0.219   dopamine receptor D3 isoform e 
ADRB3                 0.212   adrenergic, beta-3-, receptor 
ADRB2                 0.210   adrenergic, beta-2-, receptor, surface 
DRD3                  0.207   dopamine receptor D3 isoform a 
DRD5                  0.203   dopamine receptor D5 
HTR2A                 0.193   5-hydroxytryptamine (serotonin) receptor 2A 
HTR2C                 0.190   5-hydroxytryptamine (serotonin) receptor 2C 
ADRA2A                0.181   alpha-2A-adrenergic receptor 
HRH2                  0.178   histamine receptor H2 isoform 1 
HRH2                  0.178   histamine receptor H2 isoform 2 
HTR2B                 0.178   5-hydroxytryptamine (serotonin) receptor 2B 
HTR6                  0.175   5-hydroxytryptamine (serotonin) receptor 6 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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