Guide to the Human Genome
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Name: VAV1 Sequence: fasta or formatted (845aa) NCBI GI: 7108367
Description:

vav 1 guanine nucleotide exchange factor

Referenced in:

Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.7         48           3
 C cysteine            3.0         25           3
 D aspartate           6.0         51           2
 E glutamate           8.9         75           3
 F phenylalanine       4.9         41           2
 G glycine             5.6         47           1
 H histidine           2.4         20           1
 I isoleucine          4.6         39           2
 K lysine              6.7         57           3
 L leucine            10.3         87           3
 M methionine          2.6         22           1
 N asparagine          3.8         32           2
 P proline             4.1         35           4
 Q glutamine           5.3         45           2
 R arginine            7.1         60           2
 S serine              4.9         41           2
 T threonine           4.4         37           2
 V valine              4.6         39           1
 W tryptophan          1.5         13           2
 Y tyrosine            3.7         31           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vav 1 guanine nucleotide exchange factor 
VAV3                  0.575   vav 3 guanine nucleotide exchange factor isoform 1 ...
VAV2                  0.497   vav 2 guanine nucleotide exchange factor isoform 2 [...
VAV2                  0.483   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV3                  0.145   vav 3 guanine nucleotide exchange factor isoform 2 ...
GRAP                  0.054   GRB2-related adaptor protein 
PREX1                 0.046   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PREX2                 0.045   DEP domain containing 2 isoform b 
PREX2                 0.045   DEP domain containing 2 isoform a 
ARHGEF4               0.045   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.045   Rho guanine nucleotide exchange factor 4 isoform b [...
PLEKHG1               0.044   pleckstrin homology domain containing, family G (wit...
SPATA13               0.042   spermatogenesis associated 13 
ARHGEF9               0.042   Cdc42 guanine exchange factor 9 
GRB2                  0.041   growth factor receptor-bound protein 2 isoform 1 [Hom...
PLEKHG2               0.038   common-site lymphoma/leukemia guanine nucleotide ex...
MCF2L                 0.036   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.036   MCF.2 cell line derived transforming sequence-like ...
ARHGEF12              0.034   Rho guanine nucleotide exchange factor (GEF) 12 [Homo...
FGD2                  0.034   FYVE, RhoGEF and PH domain containing 2 
MCF2                  0.034   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.034   MCF.2 cell line derived transforming sequence isofo...
ARHGEF1               0.034   Rho guanine nucleotide exchange factor 1 isoform 1 [...
ARHGEF1               0.034   Rho guanine nucleotide exchange factor 1 isoform 3 [...
ARHGEF1               0.034   Rho guanine nucleotide exchange factor 1 isoform 2 [...
PLEKHG3               0.033   pleckstrin homology domain containing, family G, mem...
TIAM1                 0.032   T-cell lymphoma invasion and metastasis 1 
ARHGEF17              0.032   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
ECT2                  0.031   epithelial cell transforming sequence 2 oncogene pro...
TIAM2                 0.031   T-cell lymphoma invasion and metastasis 2 isoform a ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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