Guide to the Human Genome
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Name: VAV2 Sequence: fasta or formatted (839aa) NCBI GI: 40549448
Description:

vav 2 guanine nucleotide exchange factor isoform 2

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [878aa] vav 2 guanine nucleotide exchange factor isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             4.9         41           2
 C cysteine            2.5         21           2
 D aspartate           6.7         56           3
 E glutamate           7.9         66           3
 F phenylalanine       4.9         41           2
 G glycine             5.4         45           2
 H histidine           2.6         22           2
 I isoleucine          4.9         41           2
 K lysine              7.7         65           2
 L leucine             9.5         80           3
 M methionine          3.0         25           1
 N asparagine          3.5         29           2
 P proline             4.9         41           2
 Q glutamine           4.4         37           2
 R arginine            6.1         51           1
 S serine              6.2         52           3
 T threonine           3.8         32           2
 V valine              6.2         52           2
 W tryptophan          1.4         12           2
 Y tyrosine            3.6         30           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vav 2 guanine nucleotide exchange factor isoform 2 [... 
VAV2                  0.984   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV3                  0.536   vav 3 guanine nucleotide exchange factor isoform 1 ...
VAV1                  0.503   vav 1 guanine nucleotide exchange factor 
VAV3                  0.148   vav 3 guanine nucleotide exchange factor isoform 2 ...
PREX2                 0.049   DEP domain containing 2 isoform b 
PREX2                 0.049   DEP domain containing 2 isoform a 
PREX1                 0.048   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PLEKHG2               0.048   common-site lymphoma/leukemia guanine nucleotide ex...
GRAP                  0.046   GRB2-related adaptor protein 
SPATA13               0.046   spermatogenesis associated 13 
PLEKHG1               0.045   pleckstrin homology domain containing, family G (wit...
ARHGEF4               0.044   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.044   Rho guanine nucleotide exchange factor 4 isoform b [...
ARHGEF9               0.043   Cdc42 guanine exchange factor 9 
GRB2                  0.039   growth factor receptor-bound protein 2 isoform 1 [Hom...
ARHGEF17              0.035   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
FGD3                  0.035   FYVE, RhoGEF and PH domain containing 3 
FGD3                  0.035   FYVE, RhoGEF and PH domain containing 3 
PLEKHG3               0.035   pleckstrin homology domain containing, family G, mem...
NGEF                  0.034   neuronal guanine nucleotide exchange factor isoform...
NGEF                  0.034   neuronal guanine nucleotide exchange factor isoform...
RASGRF1               0.032   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.032   Ras protein-specific guanine nucleotide-releasing fa...
MCF2L                 0.031   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.031   MCF.2 cell line derived transforming sequence-like ...
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
ITSN1                 0.031   intersectin 1 isoform ITSN-l 
DNMBP                 0.031   dynamin binding protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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