PREX1 26431

Name: PREX1	Sequence: fasta or formatted (1659aa)		NCBI GI: 34452732
Description: phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1		Referenced in: Additional Interaction Domain Families Rho and Rac
Composition: Amino acid Percentage Count Longest homopolymer A alanine 7.0 116 3 C cysteine 2.8 47 1 D aspartate 5.0 83 2 E glutamate 8.3 138 2 F phenylalanine 3.5 58 2 G glycine 6.3 104 2 H histidine 2.7 44 2 I isoleucine 4.5 75 2 K lysine 5.9 98 2 L leucine 11.3 188 3 M methionine 2.3 38 3 N asparagine 4.0 66 3 P proline 4.3 72 2 Q glutamine 4.9 82 2 R arginine 5.8 96 3 S serine 7.5 125 2 T threonine 4.3 72 2 V valine 5.8 96 3 W tryptophan 0.7 11 1 Y tyrosine 3.0 50 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 phosphatidylinositol-3,4,5-trisphosphate-dependent R... PREX2 0.546 DEP domain containing 2 isoform a PREX2 0.340 DEP domain containing 2 isoform b ARHGEF4 0.060 Rho guanine nucleotide exchange factor 4 isoform b [... ARHGEF4 0.060 Rho guanine nucleotide exchange factor 4 isoform a [... SPATA13 0.054 spermatogenesis associated 13 ARHGEF9 0.054 Cdc42 guanine exchange factor 9 DEPDC6 0.035 DEP domain containing 6 PLEKHG1 0.029 pleckstrin homology domain containing, family G (wit... INPP4A 0.029 inositol polyphosphate-4-phosphatase, type 1 isofor... INPP4A 0.029 inositol polyphosphate-4-phosphatase, type 1 isofor... INPP4A 0.029 inositol polyphosphate-4-phosphatase, type 1 isoform ... INPP4A 0.029 inositol polyphosphate-4-phosphatase, type 1 isoform ... PLEKHG2 0.028 common-site lymphoma/leukemia guanine nucleotide ex... TIAM1 0.028 T-cell lymphoma invasion and metastasis 1 FGD3 0.026 FYVE, RhoGEF and PH domain containing 3 FGD3 0.026 FYVE, RhoGEF and PH domain containing 3 ARHGEF17 0.026 Rho guanine nucleotide exchange factor (GEF) 17 [Hom... FGD2 0.026 FYVE, RhoGEF and PH domain containing 2 FGD4 0.026 FYVE, RhoGEF and PH domain containing 4 VAV2 0.025 vav 2 guanine nucleotide exchange factor isoform 1 ... FGD1 0.025 faciogenital dysplasia protein VAV2 0.025 vav 2 guanine nucleotide exchange factor isoform 2 [... TIAM2 0.024 T-cell lymphoma invasion and metastasis 2 isoform a ... VAV1 0.024 vav 1 guanine nucleotide exchange factor TIAM2 0.024 T-cell lymphoma invasion and metastasis 2 isoform b ... FLJ41603 0.024 hypothetical protein LOC389337 DNMBP 0.023 dynamin binding protein FARP2 0.023 FERM, RhoGEF and pleckstrin domain protein 2 ARHGEF6 0.023 Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo... Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.