Guide to the Human Genome
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Name: ARHGEF1 Sequence: fasta or formatted (927aa) NCBI GI: 39777606
Description:

Rho guanine nucleotide exchange factor 1 isoform 1

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [912aa] Rho guanine nucleotide exchange factor 1 isoform 2
alt prot [879aa] Rho guanine nucleotide exchange factor 1 isoform 3
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.0         65           2
 C cysteine            1.3         12           2
 D aspartate           5.5         51           2
 E glutamate          10.4         96           3
 F phenylalanine       3.3         31           2
 G glycine             6.0         56           3
 H histidine           2.3         21           2
 I isoleucine          2.3         21           2
 K lysine              4.7         44           3
 L leucine            12.7        118           5
 M methionine          2.4         22           1
 N asparagine          2.0         19           1
 P proline             7.7         71           2
 Q glutamine           5.1         47           2
 R arginine            8.2         76           2
 S serine              7.6         70           3
 T threonine           4.3         40           1
 V valine              5.4         50           2
 W tryptophan          1.0          9           1
 Y tyrosine            0.9          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho guanine nucleotide exchange factor 1 isoform 1 [... 
ARHGEF1               0.984   Rho guanine nucleotide exchange factor 1 isoform 2 [...
ARHGEF1               0.936   Rho guanine nucleotide exchange factor 1 isoform 3 [...
ARHGEF12              0.274   Rho guanine nucleotide exchange factor (GEF) 12 [Homo...
ARHGEF11              0.231   Rho guanine nucleotide exchange factor (GEF) 11 isof...
ARHGEF11              0.231   Rho guanine nucleotide exchange factor (GEF) 11 isofo...
AKAP13                0.090   A-kinase anchor protein 13 isoform 1 
AKAP13                0.090   A-kinase anchor protein 13 isoform 3 
AKAP13                0.090   A-kinase anchor protein 13 isoform 2 
ARHGEF18              0.085   Rho/Rac guanine nucleotide exchange factor 18 isofo...
ARHGEF18              0.083   Rho/Rac guanine nucleotide exchange factor 18 isofor...
ARHGEF2               0.078   Rho/Rac guanine nucleotide exchange factor 2 isofor...
ARHGEF2               0.078   Rho/Rac guanine nucleotide exchange factor 2 isofor...
ARHGEF2               0.078   Rho/Rac guanine nucleotide exchange factor 2 isoofor...
RGNEF                 0.068   Rho-guanine nucleotide exchange factor 
PLEKHG5               0.061   pleckstrin homology domain containing family G membe...
PLEKHG5               0.061   pleckstrin homology domain containing family G memb...
PLEKHG5               0.061   pleckstrin homology domain containing family G memb...
PLEKHG5               0.061   pleckstrin homology domain containing family G memb...
PLEKHG5               0.061   pleckstrin homology domain containing family G memb...
ITSN2                 0.049   intersectin 2 isoform 3 
ITSN2                 0.049   intersectin 2 isoform 1 
ITSN1                 0.047   intersectin 1 isoform ITSN-l 
PLEKHG6               0.043   pleckstrin homology domain-containing family G memb...
PLEKHG6               0.043   pleckstrin homology domain-containing family G memb...
PLEKHG6               0.043   pleckstrin homology domain-containing family G memb...
NET1                  0.032   neuroepithelial cell transforming gene 1 isoform 1 ...
NET1                  0.032   neuroepithelial cell transforming gene 1 isoform 2 [...
VAV1                  0.032   vav 1 guanine nucleotide exchange factor 
ARHGEF3               0.031   Rho guanine nucleotide exchange factor 3 isoform 2 ...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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