Guide to the Human Genome
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Name: ARHGEF4 Sequence: fasta or formatted (690aa) NCBI GI: 15011979
Description:

Rho guanine nucleotide exchange factor 4 isoform a

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [670aa] Rho guanine nucleotide exchange factor 4 isoform b
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.2         50           2
 C cysteine            2.5         17           1
 D aspartate           6.7         46           3
 E glutamate           7.7         53           2
 F phenylalanine       3.3         23           2
 G glycine             5.5         38           4
 H histidine           3.9         27           2
 I isoleucine          4.1         28           2
 K lysine              6.1         42           2
 L leucine             9.6         66           2
 M methionine          2.0         14           1
 N asparagine          2.8         19           2
 P proline             5.1         35           1
 Q glutamine           6.2         43           3
 R arginine            7.4         51           2
 S serine              6.4         44           3
 T threonine           4.1         28           2
 V valine              5.2         36           2
 W tryptophan          2.0         14           3
 Y tyrosine            2.3         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Rho guanine nucleotide exchange factor 4 isoform a [... 
ARHGEF4               0.929   Rho guanine nucleotide exchange factor 4 isoform b [...
SPATA13               0.478   spermatogenesis associated 13 
ARHGEF9               0.426   Cdc42 guanine exchange factor 9 
LOC730032             0.202   PREDICTED: similar to Rho guanine nucleotide exchan...
PREX1                 0.142   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PREX2                 0.142   DEP domain containing 2 isoform b 
PREX2                 0.142   DEP domain containing 2 isoform a 
ARHGEF7               0.079   PAK-interacting exchange factor beta isoform d [Hom...
ARHGEF7               0.079   PAK-interacting exchange factor beta isoform c [Hom...
ARHGEF7               0.079   PAK-interacting exchange factor beta isoform b [Homo...
ARHGEF7               0.076   PAK-interacting exchange factor beta isoform a [Hom...
ARHGEF7               0.076   PAK-interacting exchange factor beta isoform a 
PLEKHG1               0.068   pleckstrin homology domain containing, family G (wit...
PLEKHG2               0.064   common-site lymphoma/leukemia guanine nucleotide ex...
FARP2                 0.064   FERM, RhoGEF and pleckstrin domain protein 2 
ITSN1                 0.059   intersectin 1 isoform ITSN-l 
ARHGEF6               0.059   Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...
MCF2L                 0.056   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.056   MCF.2 cell line derived transforming sequence-like ...
MCF2                  0.056   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.056   MCF.2 cell line derived transforming sequence isofo...
VAV1                  0.056   vav 1 guanine nucleotide exchange factor 
ITSN2                 0.056   intersectin 2 isoform 3 
ITSN2                 0.056   intersectin 2 isoform 1 
KALRN                 0.054   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.054   kalirin, RhoGEF kinase isoform 3 
PLEKHG3               0.054   pleckstrin homology domain containing, family G, mem...
FGD4                  0.054   FYVE, RhoGEF and PH domain containing 4 
FGD3                  0.053   FYVE, RhoGEF and PH domain containing 3 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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