Guide to the Human Genome
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Name: VAV2 Sequence: fasta or formatted (878aa) NCBI GI: 197304715
Description:

vav 2 guanine nucleotide exchange factor isoform 1

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [839aa] vav 2 guanine nucleotide exchange factor isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.1         45           2
 C cysteine            2.5         22           2
 D aspartate           6.4         56           3
 E glutamate           7.5         66           3
 F phenylalanine       5.1         45           2
 G glycine             5.5         48           2
 H histidine           2.6         23           2
 I isoleucine          4.8         42           2
 K lysine              7.5         66           2
 L leucine             9.3         82           3
 M methionine          3.1         27           1
 N asparagine          3.4         30           2
 P proline             5.0         44           2
 Q glutamine           4.6         40           2
 R arginine            5.9         52           1
 S serine              6.9         61           3
 T threonine           3.6         32           2
 V valine              5.9         52           2
 W tryptophan          1.5         13           2
 Y tyrosine            3.6         32           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vav 2 guanine nucleotide exchange factor isoform 1 ... 
VAV2                  0.939   vav 2 guanine nucleotide exchange factor isoform 2 [...
VAV3                  0.501   vav 3 guanine nucleotide exchange factor isoform 1 ...
VAV1                  0.466   vav 1 guanine nucleotide exchange factor 
VAV3                  0.137   vav 3 guanine nucleotide exchange factor isoform 2 ...
PREX2                 0.048   DEP domain containing 2 isoform b 
PREX2                 0.048   DEP domain containing 2 isoform a 
PREX1                 0.047   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PLEKHG2               0.046   common-site lymphoma/leukemia guanine nucleotide ex...
SPATA13               0.044   spermatogenesis associated 13 
PLEKHG1               0.042   pleckstrin homology domain containing, family G (wit...
ARHGEF9               0.042   Cdc42 guanine exchange factor 9 
ARHGEF4               0.042   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.042   Rho guanine nucleotide exchange factor 4 isoform b [...
GRAP                  0.038   GRB2-related adaptor protein 
ARHGEF17              0.034   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
GRB2                  0.033   growth factor receptor-bound protein 2 isoform 1 [Hom...
PLEKHG3               0.033   pleckstrin homology domain containing, family G, mem...
RASGRF1               0.031   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.031   Ras protein-specific guanine nucleotide-releasing fa...
NGEF                  0.031   neuronal guanine nucleotide exchange factor isoform...
NGEF                  0.031   neuronal guanine nucleotide exchange factor isoform...
FGD3                  0.031   FYVE, RhoGEF and PH domain containing 3 
FGD3                  0.031   FYVE, RhoGEF and PH domain containing 3 
MCF2                  0.030   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.030   MCF.2 cell line derived transforming sequence isofo...
ITSN1                 0.029   intersectin 1 isoform ITSN-l 
MCF2L                 0.029   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.029   MCF.2 cell line derived transforming sequence-like ...
DNMBP                 0.028   dynamin binding protein 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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