Guide to the Human Genome
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Name: FGD2 Sequence: fasta or formatted (655aa) NCBI GI: 189217917
Description:

FYVE, RhoGEF and PH domain containing 2

Referenced in:

Rho and Rac
Zinc Finger Proteins

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.6         50           3
 C cysteine            2.0         13           1
 D aspartate           5.0         33           2
 E glutamate           8.2         54           2
 F phenylalanine       3.8         25           2
 G glycine             4.9         32           1
 H histidine           1.8         12           2
 I isoleucine          3.5         23           1
 K lysine              4.9         32           2
 L leucine            10.1         66           3
 M methionine          2.6         17           1
 N asparagine          2.9         19           2
 P proline             6.0         39           2
 Q glutamine           7.0         46           2
 R arginine            7.9         52           3
 S serine              7.0         46           2
 T threonine           4.0         26           1
 V valine              6.3         41           2
 W tryptophan          1.7         11           1
 Y tyrosine            2.7         18           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   FYVE, RhoGEF and PH domain containing 2 
FGD4                  0.439   FYVE, RhoGEF and PH domain containing 4 
FGD1                  0.427   faciogenital dysplasia protein 
FGD3                  0.342   FYVE, RhoGEF and PH domain containing 3 
FGD3                  0.342   FYVE, RhoGEF and PH domain containing 3 
FGD6                  0.198   FYVE, RhoGEF and PH domain containing 6 
FGD5                  0.132   FYVE, RhoGEF and PH domain containing 5 
FARP1                 0.078   FERM, RhoGEF, and pleckstrin domain protein 1 isoform...
FARP2                 0.072   FERM, RhoGEF and pleckstrin domain protein 2 
PREX1                 0.066   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
PREX2                 0.065   DEP domain containing 2 isoform b 
PREX2                 0.065   DEP domain containing 2 isoform a 
ARHGEF17              0.053   Rho guanine nucleotide exchange factor (GEF) 17 [Hom...
MCF2L                 0.048   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.048   MCF.2 cell line derived transforming sequence-like ...
ARHGEF5               0.048   rho guanine nucleotide exchange factor 5 
ARHGEF4               0.048   Rho guanine nucleotide exchange factor 4 isoform a [...
ARHGEF4               0.048   Rho guanine nucleotide exchange factor 4 isoform b [...
ITSN1                 0.048   intersectin 1 isoform ITSN-l 
PLEKHF2               0.047   phafin 2 
SGEF                  0.047   Src homology 3 domain-containing guanine nucleotide...
KALRN                 0.045   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.045   kalirin, RhoGEF kinase isoform 3 
ARHGEF15              0.045   Rho guanine exchange factor 15 
VAV1                  0.045   vav 1 guanine nucleotide exchange factor 
PLEKHG2               0.044   common-site lymphoma/leukemia guanine nucleotide ex...
RASGRF1               0.044   Ras protein-specific guanine nucleotide-releasing f...
RASGRF1               0.044   Ras protein-specific guanine nucleotide-releasing fa...
ECT2                  0.044   epithelial cell transforming sequence 2 oncogene pro...
TRIO                  0.044   triple functional domain (PTPRF interacting) 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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