Guide to the Human Genome
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Name: VAV3 Sequence: fasta or formatted (287aa) NCBI GI: 120432042
Description:

vav 3 guanine nucleotide exchange factor isoform 2

Referenced in:

Rho and Rac

Other entries for this name:
alt prot [847aa] vav 3 guanine nucleotide exchange factor isoform 1
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.9         17           1
 C cysteine            1.4          4           1
 D aspartate           3.8         11           1
 E glutamate           7.7         22           2
 F phenylalanine       4.2         12           2
 G glycine             8.0         23           1
 H histidine           2.8          8           2
 I isoleucine          3.8         11           1
 K lysine              7.0         20           1
 L leucine             9.4         27           2
 M methionine          2.1          6           1
 N asparagine          4.2         12           2
 P proline             7.0         20           3
 Q glutamine           3.5         10           1
 R arginine            6.6         19           2
 S serine              5.9         17           1
 T threonine           5.2         15           2
 V valine              5.6         16           2
 W tryptophan          1.7          5           2
 Y tyrosine            4.2         12           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   vav 3 guanine nucleotide exchange factor isoform 2 ... 
VAV3                  0.972   vav 3 guanine nucleotide exchange factor isoform 1 ...
VAV2                  0.441   vav 2 guanine nucleotide exchange factor isoform 2 [...
VAV1                  0.435   vav 1 guanine nucleotide exchange factor 
VAV2                  0.425   vav 2 guanine nucleotide exchange factor isoform 1 ...
GRAP                  0.124   GRB2-related adaptor protein 
PLCG2                 0.100   phospholipase C, gamma 2 
PLCG1                 0.096   phospholipase C, gamma 1 isoform a 
PLCG1                 0.096   phospholipase C, gamma 1 isoform b 
GRB2                  0.094   growth factor receptor-bound protein 2 isoform 1 [Hom...
CRKL                  0.077   v-crk sarcoma virus CT10 oncogene homolog (avian)-lik...
SRC                   0.073   proto-oncogene tyrosine-protein kinase SRC 
SRC                   0.073   proto-oncogene tyrosine-protein kinase SRC 
FYN                   0.070   protein-tyrosine kinase fyn isoform a 
FYN                   0.070   protein-tyrosine kinase fyn isoform c 
FYN                   0.070   protein-tyrosine kinase fyn isoform b 
YES1                  0.068   viral oncogene yes-1 homolog 1 
MATK                  0.068   megakaryocyte-associated tyrosine kinase isoform c [...
MATK                  0.068   megakaryocyte-associated tyrosine kinase isoform b [...
MATK                  0.068   megakaryocyte-associated tyrosine kinase isoform a [...
PIK3R2                0.068   phosphoinositide-3-kinase, regulatory subunit 2 (beta...
FGR                   0.066   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.066   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.066   proto-oncogene tyrosine-protein kinase FGR 
ABL1                  0.065   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.065   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.063   arg tyrosine kinase isoform c 
ABL2                  0.063   arg tyrosine kinase isoform b 
ABL2                  0.063   arg tyrosine kinase isoform e 
ABL2                  0.063   arg tyrosine kinase isoform d 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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