Guide to the Human Genome
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Name: GRAP Sequence: fasta or formatted (217aa) NCBI GI: 5729856
Description:

GRB2-related adaptor protein

Referenced in:

Receptor Tyrosine Kinases

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             5.5         12           1
 C cysteine            0.9          2           1
 D aspartate           5.1         11           2
 E glutamate           8.8         19           2
 F phenylalanine       7.4         16           2
 G glycine             6.0         13           1
 H histidine           2.3          5           1
 I isoleucine          4.6         10           2
 K lysine              5.5         12           2
 L leucine             8.8         19           2
 M methionine          1.4          3           1
 N asparagine          3.7          8           1
 P proline             5.1         11           1
 Q glutamine           5.1         11           1
 R arginine            7.8         17           2
 S serine              8.3         18           2
 T threonine           2.3          5           3
 V valine              5.5         12           1
 W tryptophan          2.3          5           2
 Y tyrosine            3.7          8           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   GRB2-related adaptor protein 
GRB2                  0.605   growth factor receptor-bound protein 2 isoform 1 [Hom...
GRB2                  0.435   growth factor receptor-bound protein 2 isoform 2 [Ho...
LOC400581             0.423   hypothetical protein LOC400581 
GRAP2                 0.329   GRB2-related adaptor protein 2 
VAV1                  0.217   vav 1 guanine nucleotide exchange factor 
VAV2                  0.187   vav 2 guanine nucleotide exchange factor isoform 2 [...
ABL1                  0.182   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.182   c-abl oncogene 1, receptor tyrosine kinase isoform b...
ABL2                  0.177   arg tyrosine kinase isoform c 
ABL2                  0.177   arg tyrosine kinase isoform b 
ABL2                  0.177   arg tyrosine kinase isoform e 
ABL2                  0.177   arg tyrosine kinase isoform d 
ABL2                  0.177   arg tyrosine kinase isoform a 
NCK1                  0.177   NCK adaptor protein 1 
FRK                   0.175   fyn-related kinase 
VAV2                  0.173   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV3                  0.168   vav 3 guanine nucleotide exchange factor isoform 2 ...
VAV3                  0.168   vav 3 guanine nucleotide exchange factor isoform 1 ...
CSK                   0.163   c-src tyrosine kinase 
CSK                   0.163   c-src tyrosine kinase 
FYN                   0.163   protein-tyrosine kinase fyn isoform c 
FGR                   0.158   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.158   proto-oncogene tyrosine-protein kinase FGR 
FGR                   0.158   proto-oncogene tyrosine-protein kinase FGR 
FYN                   0.156   protein-tyrosine kinase fyn isoform b 
FYN                   0.156   protein-tyrosine kinase fyn isoform a 
CRK                   0.156   v-crk sarcoma virus CT10 oncogene homolog isoform a ...
CRK                   0.156   v-crk sarcoma virus CT10 oncogene homolog isoform b ...
NCK2                  0.156   NCK adaptor protein 2 isoform A 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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