Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help
Name: PLEKHG2 Sequence: fasta or formatted (1386aa) NCBI GI: 164565408
Description:

common-site lymphoma/leukemia guanine nucleotide exchange factor

Referenced in:

Inositol Pathways
Rho and Rac

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             7.9        110           3
 C cysteine            1.7         24           2
 D aspartate           3.9         54           1
 E glutamate           7.2        100           8
 F phenylalanine       2.2         31           2
 G glycine             8.4        117           6
 H histidine           2.7         38           1
 I isoleucine          3.2         45           1
 K lysine              2.5         35           1
 L leucine            11.3        156           3
 M methionine          1.2         16           1
 N asparagine          1.5         21           1
 P proline            13.2        183           5
 Q glutamine           5.5         76           2
 R arginine            6.0         83           3
 S serine             10.0        139           3
 T threonine           4.8         67           2
 V valine              4.6         64           1
 W tryptophan          0.8         11           1
 Y tyrosine            1.2         16           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   common-site lymphoma/leukemia guanine nucleotide ex... 
PLEKHG1               0.110   pleckstrin homology domain containing, family G (wit...
PLEKHG3               0.086   pleckstrin homology domain containing, family G, mem...
SPATA13               0.035   spermatogenesis associated 13 
MCF2L                 0.034   MCF.2 cell line derived transforming sequence-like ...
MCF2L                 0.034   MCF.2 cell line derived transforming sequence-like ...
ARHGEF4               0.033   Rho guanine nucleotide exchange factor 4 isoform b [...
PREX1                 0.033   phosphatidylinositol-3,4,5-trisphosphate-dependent R...
TRIO                  0.033   triple functional domain (PTPRF interacting) 
ARHGEF4               0.032   Rho guanine nucleotide exchange factor 4 isoform a [...
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
MCF2                  0.031   MCF.2 cell line derived transforming sequence isofo...
KALRN                 0.031   kalirin, RhoGEF kinase isoform 1 
KALRN                 0.031   kalirin, RhoGEF kinase isoform 2 
ARHGEF9               0.029   Cdc42 guanine exchange factor 9 
VAV2                  0.029   vav 2 guanine nucleotide exchange factor isoform 1 ...
VAV2                  0.029   vav 2 guanine nucleotide exchange factor isoform 2 [...
GEFT                  0.028   RhoA/RAC/CDC42 exchange factor isoform 1 
GEFT                  0.028   RhoA/RAC/CDC42 exchange factor isoform 3 
KALRN                 0.025   kalirin, RhoGEF kinase isoform 3 
PREX2                 0.025   DEP domain containing 2 isoform b 
PREX2                 0.025   DEP domain containing 2 isoform a 
TIAM2                 0.025   T-cell lymphoma invasion and metastasis 2 isoform b ...
TIAM2                 0.025   T-cell lymphoma invasion and metastasis 2 isoform a ...
FGD4                  0.024   FYVE, RhoGEF and PH domain containing 4 
MCF2L2                0.024   Rho family guanine-nucleotide exchange factor 
VAV1                  0.024   vav 1 guanine nucleotide exchange factor 
ARHGEF6               0.023   Rac/Cdc42 guanine nucleotide exchange factor 6 [Homo...
VAV3                  0.022   vav 3 guanine nucleotide exchange factor isoform 1 ...
TIAM1                 0.022   T-cell lymphoma invasion and metastasis 1 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press