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Search of human proteins with 7019405
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|7019405 host cell factor C2 [Homo sapiens]
(792 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|7019405 host cell factor C2 [Homo sapiens] 1632 0.0
gi|98986457 host cell factor 1 [Homo sapiens] 594 e-169
gi|16945972 kelch domain containing 3 [Homo sapiens] 114 4e-25
gi|7657301 kelch domain containing 2 [Homo sapiens] 96 1e-19
gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens] 94 5e-19
gi|47717139 leucine-zipper-like transcription regulator 1 [Homo ... 82 3e-15
gi|26190616 kelch domain containing 1 [Homo sapiens] 82 3e-15
gi|62955044 F-box protein 42 [Homo sapiens] 70 8e-12
gi|44917619 kelch domain containing 10 [Homo sapiens] 69 1e-11
gi|46410931 attractin-like 1 [Homo sapiens] 64 7e-10
gi|21314675 kelch domain containing 4 [Homo sapiens] 63 1e-09
gi|205360934 fibronectin type III domain containing 3B [Homo sap... 55 3e-07
gi|205360932 fibronectin type III domain containing 3B [Homo sap... 55 3e-07
gi|21450863 attractin isoform 2 [Homo sapiens] 53 1e-06
gi|21450861 attractin isoform 1 [Homo sapiens] 53 1e-06
gi|145701025 multiple EGF-like-domains 8 [Homo sapiens] 52 2e-06
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 50 8e-06
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 50 8e-06
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 50 8e-06
gi|110349719 titin isoform N2-A [Homo sapiens] 50 8e-06
gi|110349717 titin isoform novex-2 [Homo sapiens] 50 8e-06
gi|110349713 titin isoform novex-1 [Homo sapiens] 50 8e-06
gi|110349715 titin isoform N2-B [Homo sapiens] 50 8e-06
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 49 2e-05
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 49 2e-05
gi|222352127 sidekick 2 [Homo sapiens] 46 1e-04
gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens] 46 2e-04
gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain contai... 46 2e-04
gi|158508542 kelch-like 33 [Homo sapiens] 45 2e-04
gi|239740773 PREDICTED: similar to diffuse panbronchiolitis crit... 45 2e-04
>gi|7019405 host cell factor C2 [Homo sapiens]
Length = 792
Score = 1632 bits (4227), Expect = 0.0
Identities = 792/792 (100%), Positives = 792/792 (100%)
Query: 1 MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWF 60
MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWF
Sbjct: 1 MAAPSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWF 60
Query: 61 LPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPS 120
LPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPS
Sbjct: 61 LPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPS 120
Query: 121 GLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIP 180
GLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIP
Sbjct: 121 GLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIP 180
Query: 181 VTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGT 240
VTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGT
Sbjct: 181 VTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGT 240
Query: 241 VPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLV 300
VPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLV
Sbjct: 241 VPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLV 300
Query: 301 SDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAP 360
SDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAP
Sbjct: 301 SDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAP 360
Query: 361 SQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAPNMQGVRMDPHRQG 420
SQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAPNMQGVRMDPHRQG
Sbjct: 361 SQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAPNMQGVRMDPHRQG 420
Query: 421 SNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVV 480
SNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVV
Sbjct: 421 SNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVV 480
Query: 481 DMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAV 540
DMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAV
Sbjct: 481 DMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAV 540
Query: 541 VKDETSLTTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVATVKAGERQWCD 600
VKDETSLTTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVATVKAGERQWCD
Sbjct: 541 VKDETSLTTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVATVKAGERQWCD 600
Query: 601 VGIFKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCG 660
VGIFKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCG
Sbjct: 601 VGIFKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCG 660
Query: 661 IGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQ 720
IGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQ
Sbjct: 661 IGPFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQ 720
Query: 721 IQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVR 780
IQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVR
Sbjct: 721 IQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQVR 780
Query: 781 WLQGNNKKAPLN 792
WLQGNNKKAPLN
Sbjct: 781 WLQGNNKKAPLN 792
>gi|98986457 host cell factor 1 [Homo sapiens]
Length = 2035
Score = 594 bits (1531), Expect = e-169
Identities = 301/581 (51%), Positives = 382/581 (65%), Gaps = 31/581 (5%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGDI 68
W+RV ++GPVPR RHGHRAVAI+EL+++FGGGNEGI DELHVYNTATNQWF+PAVRGDI
Sbjct: 19 WKRVVGWSGPVPRPRHGHRAVAIKELIVVFGGGNEGIVDELHVYNTATNQWFIPAVRGDI 78
Query: 69 PPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCPRL 128
PPGCAA+GFVCDGTR+LVFGGMVEYG+YSN+LYELQASRW WK++K P +G PPCPRL
Sbjct: 79 PPGCAAYGFVCDGTRLLVFGGMVEYGKYSNDLYELQASRWEWKRLKAKTPKNGPPPCPRL 138
Query: 129 GHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPS 188
GHSFSL GNKCYLFGGLAN+SED NN+PRYLND Y LEL+ GSGVV W IP+T GV+P
Sbjct: 139 GHSFSLVGNKCYLFGGLANDSEDPKNNIPRYLNDLYILELRPGSGVVAWDIPITYGVLPP 198
Query: 189 PRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKPETKGTVPLPRSLH 248
PRESHTAV+Y +KD+ K+ ++GGM G RL DLW LD++T++W+KP G PLPRSLH
Sbjct: 199 PRESHTAVVYTEKDNKKSKLVIYGGMSGCRLGDLWTLDIDTLTWNKPSLSGVAPLPRSLH 258
Query: 249 TASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKK 308
+A+ IGNKMY+FGGWVP ++ + + H+ EW+CT++ + LNLDT W T++ D+ ED
Sbjct: 259 SATTIGNKMYVFGGWVPLVMDDVKVATHEKEWKCTNTLACLNLDTMAWETILMDTLED-- 316
Query: 309 NSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEKPPAPSQVQLIKA 368
+ PR RAGHCAVAI TRLY WSGRDGY+KA N+QVCCKDLWYL+TEKPP P++VQL++A
Sbjct: 317 -NIPRARAGHCAVAINTRLYIWSGRDGYRKAWNNQVCCKDLWYLETEKPPPPARVQLVRA 375
Query: 369 TTNSFHVKWDEVSTVEGYLLQLST-DLPYQAASSDS---------------SAAPNMQGV 412
TNS V W V+T + YLLQL D+P AA++ S S AP
Sbjct: 376 NTNSLEVSWGAVATADSYLLQLQKYDIPATAATATSPTPNPVPSVPANPPKSPAPAAAAP 435
Query: 413 RMDPHRQGSNNIVPNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNA 472
+ P Q ++P + +T + T S + P A+L +
Sbjct: 436 AVQPLTQVGITLLPQAAPAPPTTTTIQVLPTVPGSSISVPTAARTQGVPAVL--KVTGPQ 493
Query: 473 SNHNSHVVDMLRKNEGPHTSANVGVLSSCLDVRTVIPETSVSSTV-SSTQTMVTQQTIKT 531
+ + +V M ++ A V V S VR V+P S TV S+ M +
Sbjct: 494 ATTGTPLVTMRPASQA--GKAPVTVTSLPAGVRMVVPTQSAQGTVIGSSPQMSGMAALAA 551
Query: 532 ESSSTN-------GAVVKDETSLTTFSTKSEVDETYALPAT 565
+++T V+ T T + T LPAT
Sbjct: 552 AAAATQKIPPSSAPTVLSVPAGTTIVKTMAVTPGTTTLPAT 592
Score = 244 bits (624), Expect = 2e-64
Identities = 128/281 (45%), Positives = 173/281 (61%), Gaps = 17/281 (6%)
Query: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572
++ TV ST ++ TES + + V + + K + A ++ V
Sbjct: 1736 LAGTVPSTVALLPSTA--TESLAPSNTFVAPQPVVVASPAKLQA-------AATLTEVAN 1786
Query: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGK-QSISKVGNAD 631
+ + P P E QW DVG+ K +V+ ++L P S +G
Sbjct: 1787 GIESLGVKPDLPPPPSKAPMKKENQWFDVGVIKGTNVMVTHYFLPPDDAVPSDDDLGT-- 1844
Query: 632 VPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVE 691
VPDY+ LKKQ+L PGT Y+FRVA IN CG GPFS+IS FKTC+PGFPGAP A++ISK+ +
Sbjct: 1845 VPDYNQLKKQELQPGTAYKFRVAGINACGRGPFSEISAFKTCLPGFPGAPCAIKISKSPD 1904
Query: 692 GIHLSWEPPTSPSGNILEYSAYLAIRTAQI-----QDNPSQLVFMRIYCGLKTSCIVTAG 746
G HL+WEPP+ SG I+EYS YLAI+++Q P+QL FMR+YCG SC+V +
Sbjct: 1905 GAHLTWEPPSVTSGKIIEYSVYLAIQSSQAGGELKSSTPAQLAFMRVYCGPSPSCLVQSS 1964
Query: 747 QLANAHIDYTSRPAIVFRISAKNEKGYGPATQVRWLQGNNK 787
L+NAHIDYT++PAI+FRI+A+NEKGYGPATQVRWLQ +K
Sbjct: 1965 SLSNAHIDYTTKPAIIFRIAARNEKGYGPATQVRWLQETSK 2005
>gi|16945972 kelch domain containing 3 [Homo sapiens]
Length = 382
Score = 114 bits (285), Expect = 4e-25
Identities = 77/258 (29%), Positives = 124/258 (48%), Gaps = 22/258 (8%)
Query: 19 VPRARHGHRAVAIRELMIIFGGGN--EGIADELHVYNTATNQWFLPAVRGDIPPGCAAHG 76
VP R+GH V I + ++++GG N EG + L+ ++ T++WF P V G +P H
Sbjct: 73 VPYMRYGHSTVLIDDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPRVSGTVPGARDGHS 132
Query: 77 FVCDGTRILVFGGMVEYGR-YSNELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLY 135
G + +FGG + +SN++++L S W + G P R HS ++
Sbjct: 133 ACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICT----KGSPARWRDFHSATML 188
Query: 136 GNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTA 195
G+ Y+FGG A+ ++N Y N + + W V+P R SH+A
Sbjct: 189 GSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTR----TEAWLDCPPTPVLPEGRRSHSA 244
Query: 196 VIYCKKDSGSPKMYVFGGMCGARLD----DLWQLDLETMSWSKPETKGTVPLPRSLHTAS 251
Y + ++Y+FGG ARL+ DLW+ + + +W K E KG P PR
Sbjct: 245 FGY------NGELYIFGGY-NARLNRHFHDLWKFNPVSFTWKKIEPKGKGPCPRRRQCCC 297
Query: 252 VIGNKMYIFGGWVPHKGE 269
++G+K+ +FGG P E
Sbjct: 298 IVGDKIVLFGGTSPSPEE 315
Score = 62.8 bits (151), Expect = 1e-09
Identities = 56/211 (26%), Positives = 89/211 (42%), Gaps = 36/211 (17%)
Query: 16 TGPVPRARHGHRAVAIRELMIIFGGGNEG---IADELHVYNTATNQWFLPAVRGDIPPGC 72
+G VP AR GH A + ++M IFGG + ++++H +T+T W L +G
Sbjct: 121 SGTVPGARDGHSACVLGKIMYIFGGYEQQADCFSNDIHKLDTSTMTWTLICTKGSPARWR 180
Query: 73 AAHGFVCDGTRILVFGGMVE-YGRY--SNELY-------ELQASRWLWKKVKPHPPPSGL 122
H G+ + VFGG + +G + +NE+Y + + WL PP+ +
Sbjct: 181 DFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDTRTEAWL------DCPPTPV 234
Query: 123 PPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVT 182
P R HS Y + Y+FGG N + R+ +D ++ + W
Sbjct: 235 LPEGRRSHSAFGYNGELYIFGGY-------NARLNRHFHDLWKFNPVSFT----WKKIEP 283
Query: 183 KGVVPSPRESHTAVIYCKKDSGSPKMYVFGG 213
KG P PR I K+ +FGG
Sbjct: 284 KGKGPCPRRRQCCCIV------GDKIVLFGG 308
Score = 61.2 bits (147), Expect = 4e-09
Identities = 66/252 (26%), Positives = 103/252 (40%), Gaps = 50/252 (19%)
Query: 127 RLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWS-IPVTKG- 184
R+ H+ G++ Y FGG + ED ++ F + L+ W+ +P K
Sbjct: 14 RVNHAAVAVGHRVYSFGGYCS-GEDYETLRQIDVHIFNAVSLR-------WTKLPPVKSA 65
Query: 185 ------VVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGAR--LDDLWQLDLETMSWSKPE 236
VVP R H+ V+ + ++GG + L+ D+ T W P
Sbjct: 66 IRGQAPVVPYMRYGHSTVLI------DDTVLLWGGRNDTEGACNVLYAFDVNTHKWFTPR 119
Query: 237 TKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEW 296
GTVP R H+A V+G MYIFGG+ DC ++ L+ T W
Sbjct: 120 VSGTVPGARDGHSACVLGKIMYIFGGY---------EQQADC---FSNDIHKLDTSTMTW 167
Query: 297 TTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGR-DGYKK-ALNSQVCCKDLWYLDT 354
T + + K S R R H A +G+ +Y + GR D + N+++ C + DT
Sbjct: 168 TLICT------KGSPARWRDFHSATMLGSHMYVFGGRADRFGPFHSNNEIYCNRIRVFDT 221
Query: 355 ------EKPPAP 360
+ PP P
Sbjct: 222 RTEAWLDCPPTP 233
>gi|7657301 kelch domain containing 2 [Homo sapiens]
Length = 406
Score = 95.9 bits (237), Expect = 1e-19
Identities = 81/277 (29%), Positives = 123/277 (44%), Gaps = 43/277 (15%)
Query: 20 PRARHGHRAVAIRELMIIFGGGNE----GIAD------ELHVYNTATNQWFLPAVRGDIP 69
P R GH AV+ M ++GG G+ D EL +YN T +W GD+P
Sbjct: 29 PAERSGHVAVSDGRHMFVWGGYKSNQVRGLYDFYLPREELWIYNMETGRWKKINTEGDVP 88
Query: 70 PGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQA---SRWL-WKKVKPHPPPSGLPPC 125
P + VC + +FGG G +N+ Y L + R L W+++ G+PP
Sbjct: 89 PSMSGSCAVCVDRVLYLFGGHHSRGN-TNKFYMLDSRSTDRVLQWERI----DCQGIPPS 143
Query: 126 PRLGHSFSLYGNKCYLFGGLANESEDS-------------NNNVPRYLNDFYELELQHGS 172
+ +Y NK FGG ED N++ PR ND + +
Sbjct: 144 SKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWNDHVHI---LDT 200
Query: 173 GVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMC-GARLDDLWQLDLETMS 231
WS P+T G PSPR +H + +VFGG AR++DL L+L+T
Sbjct: 201 ETFTWSQPITTGKAPSPRAAHACATVGNRG------FVFGGRYRDARMNDLHYLNLDTWE 254
Query: 232 WSKPETKGTVPLPRSLHTAS-VIGNKMYIFGGWVPHK 267
W++ +G P+ RS H+ + V + +++FGG+ K
Sbjct: 255 WNELIPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDK 291
Score = 58.5 bits (140), Expect = 2e-08
Identities = 49/171 (28%), Positives = 72/171 (42%), Gaps = 24/171 (14%)
Query: 44 GIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYEL 103
G D +H+ +T T W P G P AAH G R VFGG R N+L+ L
Sbjct: 190 GWNDHVHILDTETFTWSQPITTGKAPSPRAAHACATVGNRGFVFGGRYRDAR-MNDLHYL 248
Query: 104 QASRWLWKKVKPHPPPSGLPPCPRLGHSFS-LYGNKCYLFGGLANESEDSNNNVPRYLND 162
W W ++ P G+ P R HS + + + +LFGG + + ++ ++
Sbjct: 249 NLDTWEWNEL----IPQGICPVGRSWHSLTPVSSDHLFLFGGFTTDKQPLSDAWTYCISK 304
Query: 163 FYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGG 213
++ H P T+ PR HTA C D G ++ VFGG
Sbjct: 305 NEWIQFNH---------PYTE----KPRLWHTA---CASDEG--EVIVFGG 337
Score = 43.5 bits (101), Expect = 8e-04
Identities = 64/252 (25%), Positives = 92/252 (36%), Gaps = 49/252 (19%)
Query: 124 PCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFY----ELELQHGSGVVGWSI 179
P R GH G +++GG +N R L DFY EL + + W
Sbjct: 29 PAERSGHVAVSDGRHMFVWGGY-------KSNQVRGLYDFYLPREELWI-YNMETGRWKK 80
Query: 180 PVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCG-ARLDDLWQLDLET----MSWSK 234
T+G VP AV + +Y+FGG + + LD + + W +
Sbjct: 81 INTEGDVPPSMSGSCAVCVDRV------LYLFGGHHSRGNTNKFYMLDSRSTDRVLQWER 134
Query: 235 PETKGTVPLPRSLHTASVIGNKMYIFGGW-------VPHKGENTETS----PHDCEWRCT 283
+ +G P + V NK+ FGG+ V E ETS H W
Sbjct: 135 IDCQGIPPSSKDKLGVWVYKNKLIFFGGYGYLPEDKVLGTFEFDETSFWNSSHPRGWN-- 192
Query: 284 SSFSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQ 343
L+ +T W SQ P PRA H +G R + + GR Y+ A
Sbjct: 193 DHVHILDTETFTW------SQPITTGKAPSPRAAHACATVGNRGFVFGGR--YRDAR--- 241
Query: 344 VCCKDLWYLDTE 355
DL YL+ +
Sbjct: 242 --MNDLHYLNLD 251
>gi|33695109 Rab9 effector protein with kelch motifs [Homo sapiens]
Length = 372
Score = 94.0 bits (232), Expect = 5e-19
Identities = 83/279 (29%), Positives = 115/279 (41%), Gaps = 34/279 (12%)
Query: 17 GPVPRARHGHRAV-------AIRELMIIFGGGNEGIA-DELHVYNTATNQWFLPAVRGDI 68
G P AR GH A R + I GG N + ++H + +QW L +G +
Sbjct: 25 GDSPCARVGHSCSYLPPVGNAKRGKVFIVGGANPNRSFSDVHTMDLGKHQWDLDTCKGLL 84
Query: 69 PPGCAAHGFV--CDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCP 126
P A F+ C RI VFGG + G N L L W P + PP P
Sbjct: 85 PRYEHA-SFIPSCTPDRIWVFGGANQSGN-RNCLQVLNPETRTWTT----PEVTSPPPSP 138
Query: 127 RLGHSFSL-YGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGV 185
R H+ S GN+ Y+FGG ++ + + + + WS P T G
Sbjct: 139 RTFHTSSAAIGNQLYVFGGGERGAQPVQDTKLHVFD----------ANTLTWSQPETLGN 188
Query: 186 VPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARL-DDLWQLDLETMSWSKPETKGTVPLP 244
PSPR H V + K+++ GG+ G R DDL +D+ M W K G P
Sbjct: 189 PPSPRHGHVMV------AAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPTGAAPAG 242
Query: 245 RSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCT 283
+ H+A +G +YIFGG P +T H E T
Sbjct: 243 CAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWT 281
Score = 79.3 bits (194), Expect = 1e-14
Identities = 72/226 (31%), Positives = 102/226 (45%), Gaps = 48/226 (21%)
Query: 121 GLPPCPRLGHSFSLY---GN----KCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSG 173
G PC R+GHS S GN K ++ GG N R +D + ++L G
Sbjct: 25 GDSPCARVGHSCSYLPPVGNAKRGKVFIVGGA---------NPNRSFSDVHTMDL----G 71
Query: 174 VVGWSIPVTKGVVPSPRESHTAVI-YCKKDSGSPKMYVFGG--MCGARLDDLWQLDLETM 230
W + KG++P R H + I C D +++VFGG G R + L L+ ET
Sbjct: 72 KHQWDLDTCKGLLP--RYEHASFIPSCTPD----RIWVFGGANQSGNR-NCLQVLNPETR 124
Query: 231 SWSKPETKGTVPLPRSLHTASV-IGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYL 289
+W+ PE P PR+ HT+S IGN++Y+FGG GE D +
Sbjct: 125 TWTTPEVTSPPPSPRTFHTSSAAIGNQLYVFGG-----GERGAQPVQD------TKLHVF 173
Query: 290 NLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDG 335
+ +T W SQ + + P PR GH VA GT+L+ G G
Sbjct: 174 DANTLTW------SQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAG 213
Score = 65.1 bits (157), Expect = 2e-10
Identities = 62/212 (29%), Positives = 80/212 (37%), Gaps = 37/212 (17%)
Query: 7 LNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGG-GNEGIADELHVYNTATNQWFLPAVR 65
L W + + P P RHGH VA + I GG + D+LH + + +W
Sbjct: 178 LTWSQPETLGNP-PSPRHGHVMVAAGTKLFIHGGLAGDRFYDDLHCIDISDMKWQKLNPT 236
Query: 66 GDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNEL-YELQASRWLWKKVKPHPPPSGLPP 124
G P GCAAH V G + +FGGM G Y + W K PP
Sbjct: 237 GAAPAGCAAHSAVAMGKHVYIFGGMTPAGALDTMYQYHTEEQHWTLLKFDTLLPPG---- 292
Query: 125 CPRLGHSFSL--YGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVT 182
RL HS + + C A+E EDSN+ L L H + + V
Sbjct: 293 --RLDHSMCIIPWPVTC------ASEKEDSNS-----------LTLNHEAEKEDSADKVM 333
Query: 183 KGVVPSPRESHTAVIYCKKDSGSPKMYVFGGM 214
S ES TA + C VFGGM
Sbjct: 334 SHSGDSHEESQTATLLC---------LVFGGM 356
Score = 62.0 bits (149), Expect = 2e-09
Identities = 75/296 (25%), Positives = 112/296 (37%), Gaps = 75/296 (25%)
Query: 59 WFLPAVRGDIPPGCAAHGFVCDGT---------RILVFGGMVEYGRYSNELYELQASRWL 109
W+ V GD P CA G C ++ + GG R ++++ + +
Sbjct: 18 WYTLTVPGDSP--CARVGHSCSYLPPVGNAKRGKVFIVGG-ANPNRSFSDVHTMDLGKHQ 74
Query: 110 WKKVKPHPPPSGLPPC----PRLGHSF---SLYGNKCYLFGGLANESEDSNNNVPRYLND 162
W L C PR H+ S ++ ++FGG AN+S N N + LN
Sbjct: 75 WD----------LDTCKGLLPRYEHASFIPSCTPDRIWVFGG-ANQS--GNRNCLQVLNP 121
Query: 163 FYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGAR---- 218
W+ P PSPR HT+ + ++YVFGG G R
Sbjct: 122 ETRT----------WTTPEVTSPPPSPRTFHTS-----SAAIGNQLYVFGG--GERGAQP 164
Query: 219 LDD--LWQLDLETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPH 276
+ D L D T++WS+PET G P PR H G K++I GG
Sbjct: 165 VQDTKLHVFDANTLTWSQPETLGNPPSPRHGHVMVAAGTKLFIHGGLAGD---------- 214
Query: 277 DCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
R +++ +W L + + P A H AVA+G +Y + G
Sbjct: 215 ----RFYDDLHCIDISDMKWQKL------NPTGAAPAGCAAHSAVAMGKHVYIFGG 260
>gi|47717139 leucine-zipper-like transcription regulator 1 [Homo
sapiens]
Length = 840
Score = 81.6 bits (200), Expect = 3e-15
Identities = 80/296 (27%), Positives = 127/296 (42%), Gaps = 41/296 (13%)
Query: 75 HGFVCDGTRILVFGGMVEYGRYS-NELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFS 133
H V I VFGG + G+ N+L W + +G PP PR HS
Sbjct: 71 HTVVAYKDAIYVFGG--DNGKTMLNDLLRFDVKDCSWCRAFT----TGTPPAPRYHHSAV 124
Query: 134 LYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESH 193
+YG+ ++FGG + SN+N+ + ND +E + G W+ +G +P R +H
Sbjct: 125 VYGSSMFVFGGYTGDIY-SNSNL-KNKNDLFEYKFATGQ----WTEWKIEGRLPVARSAH 178
Query: 194 TAVIYCKKDSGSPKMYVFGGMCG-ARLDDLWQL---DLETMSWSKPETKGTVPLPRSLHT 249
A +Y S K+++F G G ARL+D+W + D E W + G +P
Sbjct: 179 GATVY------SDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSGEIPPSCCNFP 232
Query: 250 ASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQEDKKN 309
+V +KM++F G K N + F + D T WT + ++
Sbjct: 233 VAVCRDKMFVFSGQSGAKITN-------------NLFQFEFKDKT-WTRIPTEHLLRGSP 278
Query: 310 SRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTE--KPPAPSQV 363
P+ R GH VA LY + G L +++ C D+ + E +P + S+V
Sbjct: 279 PPPQRRYGHTMVAFDRHLYVFGG--AADNTLPNELHCYDVDFQTWEVVQPSSDSEV 332
Score = 75.9 bits (185), Expect = 1e-13
Identities = 68/268 (25%), Positives = 114/268 (42%), Gaps = 34/268 (12%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGN-EGIADELHVYNTATNQWFLPAVRGD 67
WRR+ V R H VA ++ + +FGG N + + ++L ++ W G
Sbjct: 54 WRRLPPCDEFVGARRSKHTVVAYKDAIYVFGGDNGKTMLNDLLRFDVKDCSWCRAFTTGT 113
Query: 68 IPPGCAAHGFVCDGTRILVFGGMV------EYGRYSNELYELQASRWLWKKVKPHPPPSG 121
P H V G+ + VFGG + N+L+E + + W + K G
Sbjct: 114 PPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQWTEWK----IEG 169
Query: 122 LPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPV 181
P R H ++Y +K ++F G + LND + + LQ + W
Sbjct: 170 RLPVARSAHGATVYSDKLWIFAGYDGNAR---------LNDMWTIGLQDRE-LTCWEEVA 219
Query: 182 TKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARL-DDLWQLDLETMSWSKPET--- 237
G +P P + V C+ KM+VF G GA++ ++L+Q + + +W++ T
Sbjct: 220 QSGEIP-PSCCNFPVAVCR-----DKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHL 273
Query: 238 -KGTVPLP--RSLHTASVIGNKMYIFGG 262
+G+ P P R HT +Y+FGG
Sbjct: 274 LRGSPPPPQRRYGHTMVAFDRHLYVFGG 301
Score = 65.5 bits (158), Expect = 2e-10
Identities = 52/159 (32%), Positives = 74/159 (46%), Gaps = 22/159 (13%)
Query: 179 IPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCG-ARLDDLWQLDLETMSWSKPET 237
+P V + R HT V Y KD+ +YVFGG G L+DL + D++ SW + T
Sbjct: 57 LPPCDEFVGARRSKHTVVAY--KDA----IYVFGGDNGKTMLNDLLRFDVKDCSWCRAFT 110
Query: 238 KGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWT 297
GT P PR H+A V G+ M++FGG+ N+ + F Y T +WT
Sbjct: 111 TGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKN------DLFEY-KFATGQWT 163
Query: 298 TLVSDSQEDKKNSR-PRPRAGHCAVAIGTRLYFWSGRDG 335
E K R P R+ H A +L+ ++G DG
Sbjct: 164 -------EWKIEGRLPVARSAHGATVYSDKLWIFAGYDG 195
Score = 56.6 bits (135), Expect = 9e-08
Identities = 80/346 (23%), Positives = 121/346 (34%), Gaps = 81/346 (23%)
Query: 8 NWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGI--------ADELHVYNTATNQW 59
+W R + TG P R+ H AV M +FGG I ++L Y AT QW
Sbjct: 104 SWCRAFT-TGTPPAPRYHHSAVVYGSSMFVFGGYTGDIYSNSNLKNKNDLFEYKFATGQW 162
Query: 60 FLPAVRGDIPPGCAAHGFVCDGTRILVFGG---------MVEYGRYSNEL---------- 100
+ G +P +AHG ++ +F G M G EL
Sbjct: 163 TEWKIEGRLPVARSAHGATVYSDKLWIFAGYDGNARLNDMWTIGLQDRELTCWEEVAQSG 222
Query: 101 ---------------------------------YELQASRWLWKKVKPHPPPSGLPPCP- 126
++ + W ++ G PP P
Sbjct: 223 EIPPSCCNFPVAVCRDKMFVFSGQSGAKITNNLFQFEFKDKTWTRIPTEHLLRGSPPPPQ 282
Query: 127 -RLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGV 185
R GH+ + Y+FGG A +N +P L+ Y+++ Q VV S G
Sbjct: 283 RRYGHTMVAFDRHLYVFGGAA------DNTLPNELH-CYDVDFQTWE-VVQPSSDSEVGG 334
Query: 186 VPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLWQLDLETMSWSKP-ETKGTVPLP 244
P + C + P + + + D++ LD T S +P + +P
Sbjct: 335 AEVPERA------CASEE-VPTLTYEERVGFKKSRDVFGLDFGTTSAKQPTQPASELPSG 387
Query: 245 RSLHTASVIGNKMYIFGGWVPHKGENTE--TSPHDCEWRCTSSFSY 288
R H A+VI + MYIFGG V + + E C +CT Y
Sbjct: 388 RLFHAAAVISDAMYIFGGTVDNNIRSGEMYRFQFSCYPKCTLHEDY 433
>gi|26190616 kelch domain containing 1 [Homo sapiens]
Length = 406
Score = 81.6 bits (200), Expect = 3e-15
Identities = 74/268 (27%), Positives = 117/268 (43%), Gaps = 34/268 (12%)
Query: 19 VPRARHGHRAVAIRELMIIFGG-----GNEGIA--DELHVYNTATNQWFLPAVRGDIPPG 71
V R GH AV + ++GG NE DE+ Y+ + W + + G++P
Sbjct: 9 VAEERSGHCAVVDGNFLYVWGGYVSIEDNEVYLPNDEIWTYDIDSGLWRMHLMEGELPAS 68
Query: 72 CAAHGFVCDGTRILVFGGMVEYGRYSNELY----ELQASRWLWKKVKPHPPPSGLPPCPR 127
+ C ++ +FGG + G YSN LY + ++W+K+ G PP PR
Sbjct: 69 MSGSCGACINGKLYIFGGYDDKG-YSNRLYFVNLRTRDETYIWEKITDF---EGQPPTPR 124
Query: 128 LGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHG---------SGVVGWS 178
S +Y ++ FGG + + +E ++ G + W
Sbjct: 125 DKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHNDVHIFDTKTQTWF 184
Query: 179 IPVTK-GVVPSPRESHTAVIYCKKDSGSPKMYVFGG-MCGARLDDLWQLDLETMSWSKPE 236
P K GV P PR +HT + K Y+FGG + R++DL L+L+T +WS
Sbjct: 185 QPEIKGGVPPQPRAAHTCAVLGNKG------YIFGGRVLQTRMNDLHYLNLDTWTWSGRI 238
Query: 237 T-KGTVPLPRSLHTASVIG-NKMYIFGG 262
T G P RS HT + I +K+++ GG
Sbjct: 239 TINGESPKHRSWHTLTPIADDKLFLCGG 266
Score = 72.0 bits (175), Expect = 2e-12
Identities = 87/326 (26%), Positives = 126/326 (38%), Gaps = 82/326 (25%)
Query: 73 AAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRW-------LWKKVKPHPPPSGLPPC 125
+ H V DG + V+GG V NE+Y W LW+ G P
Sbjct: 14 SGHCAVVDGNFLYVWGGYVSIE--DNEVYLPNDEIWTYDIDSGLWRMHLME----GELPA 67
Query: 126 PRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWS-IPVTKG 184
G + K Y+FGG ++ Y N Y + L+ W I +G
Sbjct: 68 SMSGSCGACINGKLYIFGGYDDKG---------YSNRLYFVNLRTRDETYIWEKITDFEG 118
Query: 185 VVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDL----------WQ---------- 224
P+PR+ + +Y KD ++ FGG R +L W+
Sbjct: 119 QPPTPRDKLSCWVY--KD----RLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGWHND 172
Query: 225 ---LDLETMSWSKPETKGTVP-LPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEW 280
D +T +W +PE KG VP PR+ HT +V+GNK YIFGG V +T +D
Sbjct: 173 VHIFDTKTQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRV------LQTRMND--- 223
Query: 281 RCTSSFSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG-------- 332
YLNLDT W+ ++ + E P+ R+ H I F G
Sbjct: 224 -----LHYLNLDTWTWSGRITINGES-----PKHRSWHTLTPIADDKLFLCGGLSADNIP 273
Query: 333 -RDGYKKALNSQVCCKDLWYLDTEKP 357
DG+ + + C K L +L +P
Sbjct: 274 LSDGWIHNVTTN-CWKQLTHLPKTRP 298
Score = 57.0 bits (136), Expect = 7e-08
Identities = 63/243 (25%), Positives = 98/243 (40%), Gaps = 51/243 (20%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGN-----------------------EGI 45
W +++ F G P R ++ +I FGG G
Sbjct: 110 WEKITDFEGQPPTPRDKLSCWVYKDRLIYFGGYGCRRHSELQDCFDVHDASWEEQIFWGW 169
Query: 46 ADELHVYNTATNQWFLPAVRGDIPP-GCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQ 104
+++H+++T T WF P ++G +PP AAH G + +FGG V R N+L+ L
Sbjct: 170 HNDVHIFDTKTQTWFQPEIKGGVPPQPRAAHTCAVLGNKGYIFGGRVLQTR-MNDLHYLN 228
Query: 105 ASRWLWKKVKPHPPPSGLPPCPRLGHSFS-LYGNKCYLFGGLANESEDSNNNVPRYLNDF 163
W W +G P R H+ + + +K +L GGL S +N+P L+D
Sbjct: 229 LDTWTW---SGRITINGESPKHRSWHTLTPIADDKLFLCGGL------SADNIP--LSDG 277
Query: 164 YELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDLW 223
+ + +P T+ PR HTA + ++ VFGG DDL
Sbjct: 278 WIHNVTTNCWKQLTHLPKTR-----PRLWHTACL-----GKENEIMVFGG----SKDDLL 323
Query: 224 QLD 226
LD
Sbjct: 324 ALD 326
Score = 36.6 bits (83), Expect = 0.094
Identities = 28/98 (28%), Positives = 44/98 (44%), Gaps = 16/98 (16%)
Query: 245 RSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTLVSDSQ 304
RS H A V GN +Y++GG+V + +N P+D W ++D+ W + + +
Sbjct: 13 RSGHCAVVDGNFLYVWGGYVSIE-DNEVYLPNDEIWT-------YDIDSGLWRMHLMEGE 64
Query: 305 EDKKNSRPRPRAGHCAVAIGTRLYFWSGRD--GYKKAL 340
P +G C I +LY + G D GY L
Sbjct: 65 ------LPASMSGSCGACINGKLYIFGGYDDKGYSNRL 96
>gi|62955044 F-box protein 42 [Homo sapiens]
Length = 717
Score = 70.1 bits (170), Expect = 8e-12
Identities = 52/179 (29%), Positives = 76/179 (42%), Gaps = 30/179 (16%)
Query: 184 GVVPSPRESHTAVIYCKKDSGSPKMYVFGGM----CGARLDDLWQLDLETMSWSKPETKG 239
G + R SH+A Y S MYVFGG C A +DLW+LDL + W +P G
Sbjct: 113 GTPITQRFSHSACYYDANQS----MYVFGGCTQSSCNAAFNDLWRLDLNSKEWIRPLASG 168
Query: 240 TVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEW--RCTSSFSYLNLDTTEWT 297
+ P P++ T V + + +FGGW T SP+ R + W
Sbjct: 169 SYPSPKAGATLVVYKDLLVLFGGW-------TRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
Query: 298 TLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGYKKALNSQVCCKDLWYLDTEK 356
+V+ P P AGH + I ++ + G +L S+ D+W LD E+
Sbjct: 222 CIVT-------THGPPPMAGHSSCVIDDKMIVFGG------SLGSRQMSNDVWVLDLEQ 267
Score = 64.7 bits (156), Expect = 3e-10
Identities = 54/182 (29%), Positives = 81/182 (44%), Gaps = 20/182 (10%)
Query: 86 VFGGMVEYGRYS--NELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFG 143
VFGG + + N+L+ L + W + P SG P P+ G + +Y + LFG
Sbjct: 135 VFGGCTQSSCNAAFNDLWRLDLNSKEWIR----PLASGSYPSPKAGATLVVYKDLLVLFG 190
Query: 144 GLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDS 203
G S + R+ ++ + + W+ VT P P H++ +
Sbjct: 191 GWTRPSPYPLHQPERFFDEIHT----YSPSKNWWNCIVTTHG-PPPMAGHSSCVI----- 240
Query: 204 GSPKMYVFGGMCGARL--DDLWQLDLETMSWSKPETKGTVPLPRSLHTASVIGN-KMYIF 260
KM VFGG G+R +D+W LDLE +WSKP G P PR + VI + + I
Sbjct: 241 -DDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSKPNISGPSPHPRGGQSQIVIDDATILIL 299
Query: 261 GG 262
GG
Sbjct: 300 GG 301
Score = 59.3 bits (142), Expect = 1e-08
Identities = 38/126 (30%), Positives = 58/126 (46%), Gaps = 15/126 (11%)
Query: 16 TGPVPRARHGHRAVAIRELMIIFGGGN----------EGIADELHVYNTATNQWFLPAVR 65
+G P + G V ++L+++FGG E DE+H Y+ + N W+ V
Sbjct: 167 SGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKN-WWNCIVT 225
Query: 66 GDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGLPPC 125
PP A H +++VFGG + + SN+++ L +W W K P SG P
Sbjct: 226 THGPPPMAGHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWSK----PNISGPSPH 281
Query: 126 PRLGHS 131
PR G S
Sbjct: 282 PRGGQS 287
Score = 50.4 bits (119), Expect = 6e-06
Identities = 57/246 (23%), Positives = 93/246 (37%), Gaps = 43/246 (17%)
Query: 7 LNWR-RVSSFTGPVPRARHGHRAVAI--RELMIIFGGGNEGIAD----ELHVYNTATNQW 59
+ W R + G R H A + M +FGG + + +L + + +W
Sbjct: 102 IQWESRTYPYPGTPITQRFSHSACYYDANQSMYVFGGCTQSSCNAAFNDLWRLDLNSKEW 161
Query: 60 FLPAVRGDIPPGCAAHGFVCDGTRILVFGG--------MVEYGRYSNELYELQASRWLWK 111
P G P A V +++FGG + + R+ +E++ S+ W
Sbjct: 162 IRPLASGSYPSPKAGATLVVYKDLLVLFGGWTRPSPYPLHQPERFFDEIHTYSPSKNWWN 221
Query: 112 -KVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQH 170
V H PP P GHS + +K +FGG + S ND + L+L+
Sbjct: 222 CIVTTHGPP------PMAGHSSCVIDDKMIVFGGSLGSRQMS--------NDVWVLDLEQ 267
Query: 171 GSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCG---ARLDDLWQLDL 227
+ WS P G P PR + ++ + + GG CG A D W L +
Sbjct: 268 WA----WSKPNISGPSPHPRGGQSQIVI-----DDATILILGG-CGGPNALFKDAWLLHM 317
Query: 228 ETMSWS 233
+ W+
Sbjct: 318 HSGPWA 323
Score = 45.4 bits (106), Expect = 2e-04
Identities = 34/126 (26%), Positives = 54/126 (42%), Gaps = 7/126 (5%)
Query: 3 APSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGG--GNEGIADELHVYNTATNQWF 60
+PS W + + GP P A GH + I + MI+FGG G+ +++++ V + W
Sbjct: 214 SPSKNWWNCIVTTHGPPPMA--GHSSCVIDDKMIVFGGSLGSRQMSNDVWVLDLEQWAWS 271
Query: 61 LPAVRGDIP-PGCAAHGFVCDGTRILVFGGMVEYGRYSNE--LYELQASRWLWKKVKPHP 117
P + G P P V D IL+ GG + L + + W W+ +K
Sbjct: 272 KPNISGPSPHPRGGQSQIVIDDATILILGGCGGPNALFKDAWLLHMHSGPWAWQPLKVEN 331
Query: 118 PPSGLP 123
G P
Sbjct: 332 EEHGAP 337
>gi|44917619 kelch domain containing 10 [Homo sapiens]
Length = 442
Score = 69.3 bits (168), Expect = 1e-11
Identities = 84/320 (26%), Positives = 120/320 (37%), Gaps = 84/320 (26%)
Query: 20 PRARHGHRAVAIRELMIIFGGGNEGIAD-------------ELHVYNTATNQWFLPAVRG 66
P AR GHR VA + +FGG N + EL Y+ AT W G
Sbjct: 89 PPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWHQMGTDG 148
Query: 67 DIPPGCAAHGFVCDGTRILVFGGM----------------VEYGR--------------- 95
+P A+ V G +LVFGG V+Y R
Sbjct: 149 YMPRELASMSLVLHGNNLLVFGGTGIPFGESNGNDVHVCNVKYKRWALLSCRGKKPSRIY 208
Query: 96 ---------------------YSNELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSL 134
YS +L++L + W ++KP+ LP R H +
Sbjct: 209 GQAMAIINGSLYVFGGTTGYIYSTDLHKLDLNTREWTQLKPNNLSCDLPE-ERYRHEIAH 267
Query: 135 YGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHT 194
G + Y+ GG + + S N + Y LE + + P K P+ R H+
Sbjct: 268 DGQRIYILGGGTSWTAYSLNKI-----HAYNLETNAWEEIA--TKPHEKIGFPAARRCHS 320
Query: 195 AVIYCKKDSGSPKMYVFGGMCG-ARLDDLWQLDLETMSWSKPETKGTVPLPRSLHTASVI 253
V K D +++ GG G L D+W+L+L+T W K T+P P H A+V
Sbjct: 321 CV-QIKND-----VFICGGYNGEVILGDIWKLNLQTFQWVK--LPATMPEPVYFHCAAVT 372
Query: 254 -GNKMYIFGGWVP-HKGENT 271
MYI GG V H+ + T
Sbjct: 373 PAGCMYIHGGVVNIHENKRT 392
Score = 40.8 bits (94), Expect = 0.005
Identities = 52/215 (24%), Positives = 78/215 (36%), Gaps = 30/215 (13%)
Query: 123 PPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQH-GSGVVGWSIPV 181
PP R GH Y+FGG + ++S F EL H +GV W
Sbjct: 88 PPPARSGHRCVADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGV--WHQMG 145
Query: 182 TKGVVPSPRESHTAVIYCKKDSGSPKMYVFGG----MCGARLDDLWQLDLETMSWSKPET 237
T G +P S + V++ + VFGG + +D+ +++ W+
Sbjct: 146 TDGYMPRELASMSLVLH------GNNLLVFGGTGIPFGESNGNDVHVCNVKYKRWALLSC 199
Query: 238 KGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWT 297
+G P ++I +Y+FGG G T H L+L+T EWT
Sbjct: 200 RGKKPSRIYGQAMAIINGSLYVFGGTT---GYIYSTDLHK-----------LDLNTREWT 245
Query: 298 TLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
L + P R H G R+Y G
Sbjct: 246 QL---KPNNLSCDLPEERYRHEIAHDGQRIYILGG 277
Score = 37.4 bits (85), Expect = 0.055
Identities = 45/165 (27%), Positives = 60/165 (36%), Gaps = 40/165 (24%)
Query: 187 PSPRESHTAVIYCKKDSGSPKMYVFGGMC-------GARLDD------LWQLDLETMSWS 233
P R H V + + +YVFGG G +D LW+ T W
Sbjct: 89 PPARSGHRCV------ADNTNLYVFGGYNPDYDESGGPDNEDYPLFRELWRYHFATGVWH 142
Query: 234 KPETKGTVPLPRSLHTASVI--GNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNL 291
+ T G +PR L + S++ GN + +FGG GE+ H C N+
Sbjct: 143 QMGTDGY--MPRELASMSLVLHGNNLLVFGGTGIPFGESNGNDVHVC-----------NV 189
Query: 292 DTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSGRDGY 336
W L S KK SR G I LY + G GY
Sbjct: 190 KYKRWALL---SCRGKKPSR---IYGQAMAIINGSLYVFGGTTGY 228
>gi|46410931 attractin-like 1 [Homo sapiens]
Length = 1379
Score = 63.5 bits (153), Expect = 7e-10
Identities = 82/333 (24%), Positives = 123/333 (36%), Gaps = 84/333 (25%)
Query: 59 WFLPAVRGDIPP-GCAAHGFVCDGTRILVFGGMV-EYGRYSNEL-YELQASRWLWKKVKP 115
W LP V+ P G A+H V G + V GG Y + L Y L++S W
Sbjct: 291 WILPNVKPFSPSVGRASHKAVLHGKFMWVIGGYTFNYSSFQMVLNYNLESSIW-----NV 345
Query: 116 HPPPSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELE-------- 167
P G P R GHS +LY +++GG E+ D N ++ + +
Sbjct: 346 GTPSRG--PLQRYGHSLALYQENIFMYGGRI-ETNDGNVTDELWVFNIHSQSWSTKTPTV 402
Query: 168 LQHG----------------------------SGVVG--------------WSIPVTKGV 185
L HG S + G W +P TKG
Sbjct: 403 LGHGQQYAVEGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGA 462
Query: 186 VPSPRESHTAVIYCKKDSGSPKMYVFGGMCG------ARLDDLWQLDLETMSWSKPETKG 239
+ HT+V D + +YV GG +DDL++ ++ T +W+ + G
Sbjct: 463 IVQGGYGHTSVY----DEITKSIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESG 518
Query: 240 TVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLNLDTTEWTTL 299
R LH+A +I M IFGG + +TS + ++ F ++ EW L
Sbjct: 519 ---FARYLHSAVLINGAMLIFGG-----NTHNDTSLSNGAKCFSADFLAYDIACDEWKIL 570
Query: 300 VSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
+ N R GH AV I +Y + G
Sbjct: 571 PKPNLHRDVN-----RFGHSAVVINGSMYIFGG 598
Score = 48.1 bits (113), Expect = 3e-05
Identities = 74/274 (27%), Positives = 110/274 (40%), Gaps = 56/274 (20%)
Query: 20 PRARHGHRAVAIRELMIIFGGG---NEG-IADELHVYNTATNQWFL--PAVRGD----IP 69
P R+GH +E + ++GG N+G + DEL V+N + W P V G
Sbjct: 352 PLQRYGHSLALYQENIFMYGGRIETNDGNVTDELWVFNIHSQSWSTKTPTVLGHGQQYAV 411
Query: 70 PGCAAHGFVCDG---TRILVFGGMVEYGRYSN-ELYELQASRWLWKKVKPHPPPSGLPPC 125
G +AH D I++FG YG S+ + Y + ++ WL + K G
Sbjct: 412 EGHSAHIMELDSRDVVMIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGY--- 468
Query: 126 PRLGHSFSLYGN---KCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVT 182
GH+ S+Y Y+ GG + N ++D Y+ E+ + W+I
Sbjct: 469 ---GHT-SVYDEITKSIYVHGGY----KALPGNKYGLVDDLYKYEVNTKT----WTILKE 516
Query: 183 KGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMC--------GARL--DDLWQLDLETMSW 232
G R H+AV+ + M +FGG GA+ D D+ W
Sbjct: 517 SGFA---RYLHSAVLI------NGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEW 567
Query: 233 S---KPETKGTVPLPRSLHTASVIGNKMYIFGGW 263
KP V R H+A VI MYIFGG+
Sbjct: 568 KILPKPNLHRDVN--RFGHSAVVINGSMYIFGGF 599
Score = 46.2 bits (108), Expect = 1e-04
Identities = 54/204 (26%), Positives = 82/204 (40%), Gaps = 39/204 (19%)
Query: 34 LMIIFG-GGNEGIADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTR--ILVFGGM 90
++IIFG G + Y+ ++N W +P +G I G H V D I V GG
Sbjct: 428 MIIIFGYSAIYGYTSSIQEYHISSNTWLVPETKGAIVQGGYGHTSVYDEITKSIYVHGGY 487
Query: 91 V-----EYGRYSNELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFGGL 145
+YG ++LY+ + + W +K SG R HS L +FGG
Sbjct: 488 KALPGNKYGLV-DDLYKYEVNTKTWTILKE----SGFA---RYLHSAVLINGAMLIFGGN 539
Query: 146 ANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSP-------RESHTAVIY 198
+ +N + DF ++ W I +P P R H+AV+
Sbjct: 540 THNDTSLSNGAKCFSADFLAYDIACDE----WKI------LPKPNLHRDVNRFGHSAVVI 589
Query: 199 CKKDSGSPKMYVFGGMCGARLDDL 222
+GS MY+FGG L+D+
Sbjct: 590 ----NGS--MYIFGGFSSVLLNDI 607
Score = 34.7 bits (78), Expect = 0.36
Identities = 35/149 (23%), Positives = 57/149 (38%), Gaps = 26/149 (17%)
Query: 17 GPVPRARHGHRAV--AIRELMIIFGG-----GNE-GIADELHVYNTATNQWFLPAVRGDI 68
G + + +GH +V I + + + GG GN+ G+ D+L+ Y T W + G
Sbjct: 461 GAIVQGGYGHTSVYDEITKSIYVHGGYKALPGNKYGLVDDLYKYEVNTKTWTILKESGFA 520
Query: 69 PPGCAAHGFVCDGTRILVFGGMVEYGRYSNE----------LYELQASRWLWKKVKPHPP 118
H V +L+FGG + Y++ W K P
Sbjct: 521 R---YLHSAVLINGAMLIFGGNTHNDTSLSNGAKCFSADFLAYDIACDEW-----KILPK 572
Query: 119 PSGLPPCPRLGHSFSLYGNKCYLFGGLAN 147
P+ R GHS + Y+FGG ++
Sbjct: 573 PNLHRDVNRFGHSAVVINGSMYIFGGFSS 601
>gi|21314675 kelch domain containing 4 [Homo sapiens]
Length = 520
Score = 62.8 bits (151), Expect = 1e-09
Identities = 50/176 (28%), Positives = 82/176 (46%), Gaps = 27/176 (15%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIAD-----ELHVYNTATNQWFLPA 63
W +V S GP R GHR VA + +I+FGG +E D +++ +N T W +
Sbjct: 165 WEQVKSTGGP--SGRSGHRMVAWKRQLILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLS 222
Query: 64 VRGDIP-PGCAAHGFVCDGTRILVFGGM--------VEYGRYSNELYELQAS-----RWL 109
G P P V I+V+GG V+ G ++++ L+ +W+
Sbjct: 223 PSGTGPTPRSGCQMSVTPQGGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGREDKWV 282
Query: 110 WKKVKPHPPPSGLPPCPRLGHSFSLYGN-KCYLFGGLANESEDSNNNVPRYLNDFY 164
W ++ P SG+ P PR G S ++ N + FGG+ +E E+ + + + ND Y
Sbjct: 283 WTRMNP----SGVKPTPRSGFSVAMAPNHQTLFFGGVCDEEEEESLS-GEFFNDLY 333
Score = 62.0 bits (149), Expect = 2e-09
Identities = 74/286 (25%), Positives = 109/286 (38%), Gaps = 50/286 (17%)
Query: 18 PVPRARHGHRAVAIRELMIIFGGG-----NEGIADELHVYNTATNQWFLPAVRGDIPPGC 72
P PR ++ +I+FGG + +EL+VYNT + W + P C
Sbjct: 61 PSPRLNASLSVHPEKDELILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDIPSPPPRRC 120
Query: 73 AAHGFVC--DGTRILVFGGMV-----EYGRYSNELYELQASRWLWKKVKPHPPPSGLPPC 125
A V G ++ VFGG E + +L+ L + W++VK PSG
Sbjct: 121 AHQAVVVPQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATKTWEQVKSTGGPSG---- 176
Query: 126 PRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGV 185
R GH + + LFGG + D Y ND Y L WS G
Sbjct: 177 -RSGHRMVAWKRQLILFGGFHESTRDY-----IYYNDVYAFNLD----TFTWSKLSPSGT 226
Query: 186 VPSPRESHTAVIYCKKDSGSPK--MYVFGGMC----------GARLDDLWQLDLE----- 228
P+PR C+ S +P+ + V+GG G R D++ L E
Sbjct: 227 GPTPRSG------CQM-SVTPQGGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGRED 279
Query: 229 TMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETS 274
W++ G P PRS + ++ N +F G V + E S
Sbjct: 280 KWVWTRMNPSGVKPTPRSGFSVAMAPNHQTLFFGGVCDEEEEESLS 325
Score = 51.6 bits (122), Expect = 3e-06
Identities = 66/249 (26%), Positives = 102/249 (40%), Gaps = 50/249 (20%)
Query: 123 PPCPRLGHSFSLYGNK--CYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIP 180
PP PRL S S++ K LFGG E N N+ Y + + W
Sbjct: 60 PPSPRLNASLSVHPEKDELILFGG-----EYFNGQKTFLYNELYVYNTRKDT----W--- 107
Query: 181 VTKGVVPSP---RESHTAVIYCKKDSGSPKMYVFGGMCGA-------RLDDLWQLDLETM 230
TK +PSP R +H AV+ G +++VFGG + DLW L L T
Sbjct: 108 -TKVDIPSPPPRRCAHQAVVV---PQGGGQLWVFGGEFASPNGEQFYHYKDLWVLHLATK 163
Query: 231 SWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYLN 290
+W + ++ G P RS H ++ +FGG+ E+T ++ + N
Sbjct: 164 TWEQVKSTGG-PSGRSGHRMVAWKRQLILFGGF----HESTR------DYIYYNDVYAFN 212
Query: 291 LDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAI----GTRLYFWSGRDGYKKALNSQVCC 346
LDT W+ L + P PR+G C +++ G +Y + KK ++
Sbjct: 213 LDTFTWSKL------SPSGTGPTPRSG-CQMSVTPQGGIVVYGGYSKQRVKKDVDKGTRH 265
Query: 347 KDLWYLDTE 355
D++ L E
Sbjct: 266 SDMFLLKPE 274
Score = 50.4 bits (119), Expect = 6e-06
Identities = 68/265 (25%), Positives = 104/265 (39%), Gaps = 44/265 (16%)
Query: 84 ILVFGGMVEYGRYS---NELYELQASRWLWKKVK-PHPPPSGLPPCPRLGHSFSLYGNKC 139
+++FGG G+ + NELY + W KV P PPP C G +
Sbjct: 78 LILFGGEYFNGQKTFLYNELYVYNTRKDTWTKVDIPSPPPRR---CAHQAVVVPQGGGQL 134
Query: 140 YLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYC 199
++FGG E N + D + L L + W + G PS R H V +
Sbjct: 135 WVFGG---EFASPNGEQFYHYKDLWVLHLATKT----WEQVKSTGG-PSGRSGHRMVAWK 186
Query: 200 KKDSGSPKMYVFGGMCGARLD-----DLWQLDLETMSWSKPETKGTVPLPRSLHTASVIG 254
++ + +FGG + D D++ +L+T +WSK GT P PRS SV
Sbjct: 187 RQ------LILFGGFHESTRDYIYYNDVYAFNLDTFTWSKLSPSGTGPTPRSGCQMSVTP 240
Query: 255 NKMYIFGGWVPHKGENTETSPHDCEWRCTSSFSYL------NLDTTEWTTLVSDSQEDKK 308
GG V + G + + D + S +L D WT + +
Sbjct: 241 Q-----GGIVVYGGYSKQRVKKDVDKGTRHSDMFLLKPEDGREDKWVWTRM------NPS 289
Query: 309 NSRPRPRAG-HCAVAIGTRLYFWSG 332
+P PR+G A+A + F+ G
Sbjct: 290 GVKPTPRSGFSVAMAPNHQTLFFGG 314
>gi|205360934 fibronectin type III domain containing 3B [Homo
sapiens]
Length = 1204
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/70 (45%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEG-IHLSWEPP 700
+L+PGT YRFRV A+N G GP+S +SE T G PG A IS +G + + WE P
Sbjct: 732 NLLPGTVYRFRVRALNDGGYGPYSDVSEITTA-AGPPGQCKAPCISCTPDGCVLVGWESP 790
Query: 701 TSPSGNILEY 710
S +I EY
Sbjct: 791 DSSGADISEY 800
Score = 47.4 bits (111), Expect = 5e-05
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 23/164 (14%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI 674
Y + G SI+ VGN ++ +DL+P T YR R+ AIN G GPFS+ + KT
Sbjct: 903 YTIDLGDTSIT-VGNT-----TMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKT-R 955
Query: 675 PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIY 734
P P P + + + L W S + ++A + T Q++D + F+ IY
Sbjct: 956 PLPPLPPRLECAAAGPQSLKLKWGDSNSKT-----HAAEDIVYTLQLEDRNKR--FISIY 1008
Query: 735 CGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQ 778
G + V T FRI A +E G GP ++
Sbjct: 1009 RGPSHTYKVQR---------LTEFTCYSFRIQAASEAGEGPFSE 1043
Score = 43.5 bits (101), Expect = 8e-04
Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC--IPGFPGAPSAVRISKNVEGIHLSWEPP 700
L PGT Y+ R I+ G S+ +T PG P + K+ E +HL W+ P
Sbjct: 637 LKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKE-VHLEWDVP 695
Query: 701 TSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S SG + EYS + + +D S+ +Y G + C T G L +
Sbjct: 696 ASESGCEVSEYS----VEMTEPEDVASE-----VYHGPELEC--TVGNLLPGTV------ 738
Query: 760 AIVFRISAKNEKGYGPATQV 779
FR+ A N+ GYGP + V
Sbjct: 739 -YRFRVRALNDGGYGPYSDV 757
Score = 40.4 bits (93), Expect = 0.006
Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 21/144 (14%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC--IPGFPGAPSAVRISKNVEGIHLS 696
K L P GY FR+AA N G +S+ T IP P AP VR + + L
Sbjct: 437 KLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVR--AGITWVTLQ 494
Query: 697 WEPPTSPS-GNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P S ++ Y T +IQ++ + +F Y G +C V + + +
Sbjct: 495 WSKPEGCSPEEVITY-------TLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQY--- 544
Query: 756 TSRPAIVFRISAKNEKGYGPATQV 779
FR++A N +G ++V
Sbjct: 545 ------KFRLTASNTEGKSCPSEV 562
Score = 35.0 bits (79), Expect = 0.27
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKT--CIPGFPGAPSAVRISKNVEGIHLS 696
K Q L T Y FR+ A + G GPFS+ F T +P AP ++ N +
Sbjct: 1016 KVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGN--SCEIL 1073
Query: 697 WEPPTSPSGNILEY 710
WE S G+ + Y
Sbjct: 1074 WETVPSMKGDPVNY 1087
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 25/88 (28%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKT-----------CI------PGFPGAPSA 683
+DL+P Y R+ A N G GP+S++ +T C+ +P +PSA
Sbjct: 825 RDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSA 884
Query: 684 VRISKNVEGIHLSWEPPTSPSGNILEYS 711
+ L+WE P + IL Y+
Sbjct: 885 CLV--------LNWEEPCNNGSEILAYT 904
Score = 33.9 bits (76), Expect = 0.61
Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 22/154 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKT--CIPGFPGAPSAVRISKNVEGIHLSWE 698
+DL P T Y RV A+ G S+ F T C P P P SK+ + L W+
Sbjct: 343 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKS--SLTLQWK 400
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P I Y + + F + + G + C +T +L A + YT
Sbjct: 401 APIDNGSKITNY-------LLEWDEGKRNSGFRQCFFGSQKHCKLT--KLCPA-MGYT-- 448
Query: 759 PAIVFRISAKNEKGYGPATQ--VRWLQGNNKKAP 790
FR++A+N+ G +Q V + GN + P
Sbjct: 449 ----FRLAARNDIGTSGYSQEVVCYTLGNIPQMP 478
>gi|205360932 fibronectin type III domain containing 3B [Homo
sapiens]
Length = 1204
Score = 55.1 bits (131), Expect = 3e-07
Identities = 32/70 (45%), Positives = 41/70 (58%), Gaps = 2/70 (2%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNVEG-IHLSWEPP 700
+L+PGT YRFRV A+N G GP+S +SE T G PG A IS +G + + WE P
Sbjct: 732 NLLPGTVYRFRVRALNDGGYGPYSDVSEITTA-AGPPGQCKAPCISCTPDGCVLVGWESP 790
Query: 701 TSPSGNILEY 710
S +I EY
Sbjct: 791 DSSGADISEY 800
Score = 47.4 bits (111), Expect = 5e-05
Identities = 48/164 (29%), Positives = 72/164 (43%), Gaps = 23/164 (14%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI 674
Y + G SI+ VGN ++ +DL+P T YR R+ AIN G GPFS+ + KT
Sbjct: 903 YTIDLGDTSIT-VGNT-----TMHVMKDLLPETTYRIRIQAINEIGAGPFSQFIKAKT-R 955
Query: 675 PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIY 734
P P P + + + L W S + ++A + T Q++D + F+ IY
Sbjct: 956 PLPPLPPRLECAAAGPQSLKLKWGDSNSKT-----HAAEDIVYTLQLEDRNKR--FISIY 1008
Query: 735 CGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQ 778
G + V T FRI A +E G GP ++
Sbjct: 1009 RGPSHTYKVQR---------LTEFTCYSFRIQAASEAGEGPFSE 1043
Score = 43.5 bits (101), Expect = 8e-04
Identities = 42/140 (30%), Positives = 61/140 (43%), Gaps = 22/140 (15%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC--IPGFPGAPSAVRISKNVEGIHLSWEPP 700
L PGT Y+ R I+ G S+ +T PG P + K+ E +HL W+ P
Sbjct: 637 LKPGTLYKLRACCISTGGHSQCSESLPVRTLSIAPGQCRPPRVLGRPKHKE-VHLEWDVP 695
Query: 701 TSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S SG + EYS + + +D S+ +Y G + C T G L +
Sbjct: 696 ASESGCEVSEYS----VEMTEPEDVASE-----VYHGPELEC--TVGNLLPGTV------ 738
Query: 760 AIVFRISAKNEKGYGPATQV 779
FR+ A N+ GYGP + V
Sbjct: 739 -YRFRVRALNDGGYGPYSDV 757
Score = 40.4 bits (93), Expect = 0.006
Identities = 39/144 (27%), Positives = 60/144 (41%), Gaps = 21/144 (14%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC--IPGFPGAPSAVRISKNVEGIHLS 696
K L P GY FR+AA N G +S+ T IP P AP VR + + L
Sbjct: 437 KLTKLCPAMGYTFRLAARNDIGTSGYSQEVVCYTLGNIPQMPSAPRLVR--AGITWVTLQ 494
Query: 697 WEPPTSPS-GNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P S ++ Y T +IQ++ + +F Y G +C V + + +
Sbjct: 495 WSKPEGCSPEEVITY-------TLEIQEDENDNLFHPKYTGEDLTCTVKNLKRSTQY--- 544
Query: 756 TSRPAIVFRISAKNEKGYGPATQV 779
FR++A N +G ++V
Sbjct: 545 ------KFRLTASNTEGKSCPSEV 562
Score = 35.0 bits (79), Expect = 0.27
Identities = 24/74 (32%), Positives = 33/74 (44%), Gaps = 4/74 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKT--CIPGFPGAPSAVRISKNVEGIHLS 696
K Q L T Y FR+ A + G GPFS+ F T +P AP ++ N +
Sbjct: 1016 KVQRLTEFTCYSFRIQAASEAGEGPFSETYTFSTTKSVPPTIKAPRVTQLEGN--SCEIL 1073
Query: 697 WEPPTSPSGNILEY 710
WE S G+ + Y
Sbjct: 1074 WETVPSMKGDPVNY 1087
Score = 34.3 bits (77), Expect = 0.46
Identities = 24/88 (27%), Positives = 38/88 (43%), Gaps = 25/88 (28%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKT-----------CI------PGFPGAPSA 683
+DL+P Y R+ A N G GP+S++ +T C+ +P +PSA
Sbjct: 825 RDLLPAAQYCCRLQAFNQAGAGPYSELVLCQTPASAPDPVSTLCVLEEEPLDAYPDSPSA 884
Query: 684 VRISKNVEGIHLSWEPPTSPSGNILEYS 711
+ L+WE P + IL Y+
Sbjct: 885 CLV--------LNWEEPCNNGSEILAYT 904
Score = 33.9 bits (76), Expect = 0.61
Identities = 41/154 (26%), Positives = 62/154 (40%), Gaps = 22/154 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKT--CIPGFPGAPSAVRISKNVEGIHLSWE 698
+DL P T Y RV A+ G S+ F T C P P P SK+ + L W+
Sbjct: 343 KDLRPATDYHVRVYAMYNSVKGSCSEPVSFTTHSCAPECPFPPKLAHRSKS--SLTLQWK 400
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P I Y + + F + + G + C +T +L A + YT
Sbjct: 401 APIDNGSKITNY-------LLEWDEGKRNSGFRQCFFGSQKHCKLT--KLCPA-MGYT-- 448
Query: 759 PAIVFRISAKNEKGYGPATQ--VRWLQGNNKKAP 790
FR++A+N+ G +Q V + GN + P
Sbjct: 449 ----FRLAARNDIGTSGYSQEVVCYTLGNIPQMP 478
>gi|21450863 attractin isoform 2 [Homo sapiens]
Length = 1272
Score = 53.1 bits (126), Expect = 1e-06
Identities = 82/347 (23%), Positives = 129/347 (37%), Gaps = 67/347 (19%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGG--NEGIADELHVYNTATNQWFLPAVRG 66
W R +PRA H+AV +M + GG N + + Y+ A+ +W LP R
Sbjct: 329 WTREEYSNLKLPRA--SHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREW-LPLNRS 385
Query: 67 -DIPPGCAAHGFVCDGTRILVFGGMVEY-GRYSNELYELQASRWLWKKVKPHPPPSGLPP 124
+ H +I ++GG ++ G +NEL W + P
Sbjct: 386 VNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAV- 444
Query: 125 CPRLGHSFSLYGNK------------CYLFGGLANESEDSNNNVPRYLNDFYELELQHGS 172
+GHS + K C L+G ++N E Y+L+
Sbjct: 445 ---VGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQE-------------YDLDKNT-- 486
Query: 173 GVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARL------DDLWQLD 226
WSI T+G + H++V D + +YV GG DDL++ D
Sbjct: 487 ----WSILHTQGALVQGGYGHSSVY----DHRTRALYVHGGYKAFSANKYRLADDLYRYD 538
Query: 227 LETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSS- 285
++T W+ + R LHTA ++ M +FGG N + H +C SS
Sbjct: 539 VDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGG----NTHNDTSMSHGA--KCFSSD 589
Query: 286 FSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
F ++ W+ L N R GH AV + +Y + G
Sbjct: 590 FMAYDIACDRWSVLPRPDLHHDVN-----RFGHSAVLHNSTMYVFGG 631
Score = 38.9 bits (89), Expect = 0.019
Identities = 67/267 (25%), Positives = 103/267 (38%), Gaps = 52/267 (19%)
Query: 23 RHGHRAVAIRELMIIFGG---GNEGIADELHVYNTATNQWFLPAVRGD---IPPGCAAHG 76
R+GH ++ + ++GG + +EL V++ W L + G +AH
Sbjct: 392 RYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHI 451
Query: 77 FVCDGTRIL---VFGGMVEYGRYSN-ELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSF 132
R++ +FG YG SN + Y+L + W + G GHS
Sbjct: 452 VTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGY------GHS- 504
Query: 133 SLYGNKC---YLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSP 189
S+Y ++ Y+ GG S N R +D Y ++ W+I
Sbjct: 505 SVYDHRTRALYVHGGYKAFSA----NKYRLADDLYRYDVDTQM----WTILKDSRFF--- 553
Query: 190 RESHTAVIYCKKDSGSPKMYVFGGMC--------GARL--DDLWQLDLETMSWS---KPE 236
R HTAVI S M VFGG GA+ D D+ WS +P+
Sbjct: 554 RYLHTAVIV------SGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPD 607
Query: 237 TKGTVPLPRSLHTASVIGNKMYIFGGW 263
V R H+A + + MY+FGG+
Sbjct: 608 LHHDVN--RFGHSAVLHNSTMYVFGGF 632
>gi|21450861 attractin isoform 1 [Homo sapiens]
Length = 1429
Score = 53.1 bits (126), Expect = 1e-06
Identities = 82/347 (23%), Positives = 129/347 (37%), Gaps = 67/347 (19%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRELMIIFGGG--NEGIADELHVYNTATNQWFLPAVRG 66
W R +PRA H+AV +M + GG N + + Y+ A+ +W LP R
Sbjct: 329 WTREEYSNLKLPRA--SHKAVVNGNIMWVVGGYMFNHSDYNMVLAYDLASREW-LPLNRS 385
Query: 67 -DIPPGCAAHGFVCDGTRILVFGGMVEY-GRYSNELYELQASRWLWKKVKPHPPPSGLPP 124
+ H +I ++GG ++ G +NEL W + P
Sbjct: 386 VNNVVVRYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAV- 444
Query: 125 CPRLGHSFSLYGNK------------CYLFGGLANESEDSNNNVPRYLNDFYELELQHGS 172
+GHS + K C L+G ++N E Y+L+
Sbjct: 445 ---VGHSAHIVTLKNGRVVMLVIFGHCPLYGYISNVQE-------------YDLDKNT-- 486
Query: 173 GVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARL------DDLWQLD 226
WSI T+G + H++V D + +YV GG DDL++ D
Sbjct: 487 ----WSILHTQGALVQGGYGHSSVY----DHRTRALYVHGGYKAFSANKYRLADDLYRYD 538
Query: 227 LETMSWSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRCTSS- 285
++T W+ + R LHTA ++ M +FGG N + H +C SS
Sbjct: 539 VDTQMWTILKDSRFF---RYLHTAVIVSGTMLVFGG----NTHNDTSMSHGA--KCFSSD 589
Query: 286 FSYLNLDTTEWTTLVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
F ++ W+ L N R GH AV + +Y + G
Sbjct: 590 FMAYDIACDRWSVLPRPDLHHDVN-----RFGHSAVLHNSTMYVFGG 631
Score = 38.9 bits (89), Expect = 0.019
Identities = 67/267 (25%), Positives = 103/267 (38%), Gaps = 52/267 (19%)
Query: 23 RHGHRAVAIRELMIIFGG---GNEGIADELHVYNTATNQWFLPAVRGD---IPPGCAAHG 76
R+GH ++ + ++GG + +EL V++ W L + G +AH
Sbjct: 392 RYGHSLALYKDKIYMYGGKIDSTGNVTNELRVFHIHNESWVLLTPKAKEQYAVVGHSAHI 451
Query: 77 FVCDGTRIL---VFGGMVEYGRYSN-ELYELQASRWLWKKVKPHPPPSGLPPCPRLGHSF 132
R++ +FG YG SN + Y+L + W + G GHS
Sbjct: 452 VTLKNGRVVMLVIFGHCPLYGYISNVQEYDLDKNTWSILHTQGALVQGGY------GHS- 504
Query: 133 SLYGNKC---YLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSIPVTKGVVPSP 189
S+Y ++ Y+ GG S N R +D Y ++ W+I
Sbjct: 505 SVYDHRTRALYVHGGYKAFSA----NKYRLADDLYRYDVDTQM----WTILKDSRFF--- 553
Query: 190 RESHTAVIYCKKDSGSPKMYVFGGMC--------GARL--DDLWQLDLETMSWS---KPE 236
R HTAVI S M VFGG GA+ D D+ WS +P+
Sbjct: 554 RYLHTAVIV------SGTMLVFGGNTHNDTSMSHGAKCFSSDFMAYDIACDRWSVLPRPD 607
Query: 237 TKGTVPLPRSLHTASVIGNKMYIFGGW 263
V R H+A + + MY+FGG+
Sbjct: 608 LHHDVN--RFGHSAVLHNSTMYVFGGF 632
>gi|145701025 multiple EGF-like-domains 8 [Homo sapiens]
Length = 2778
Score = 52.0 bits (123), Expect = 2e-06
Identities = 84/345 (24%), Positives = 131/345 (37%), Gaps = 50/345 (14%)
Query: 9 WRRVSSFTGPVPRARHGHRAVAIRE--LMIIFGGG--NEGIADELHVYNTATNQWFLPAV 64
W VS+ P AR G + L+ +FGG N + D L +YN + N W
Sbjct: 215 WHNVSA-RDPAFSARIGAAGAFLSPPGLLAVFGGQDLNNALGD-LVLYNFSANTW----E 268
Query: 65 RGDIPPGCAA---HGFVCDGTRILVFGGMVEYGRYSNELYELQA-SRWLWKKVKPHPPPS 120
D+ P AA H V +++ GG + G +N+++ R W+ + P S
Sbjct: 269 SWDLSPAPAARHSHVAVAWAGSLVLMGGELADGSLTNDVWAFSPLGRGHWELLAPPASSS 328
Query: 121 GLPPCPRLGHSFSLYGNK-CYLFGGLANESEDSNNNVPRYLNDFYELELQHGSGVVGWSI 179
PP GH+ +L + Y+ GG S+ + L SG W
Sbjct: 329 SGPP-GLAGHAAALVDDVWLYVSGGRTPHDLFSSG--------LFRFRLDSTSGGY-WEQ 378
Query: 180 PVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGM--CGARLD------DLWQLDLETMS 231
+ G P H+ V + S + V GG AR +L+ +D +
Sbjct: 379 VIPAGGRPPAATGHSMVFHAP----SRALLVHGGHRPSTARFSVRVNSTELFHVDRHVWT 434
Query: 232 WSKPETKGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWRC-TSSFSYLN 290
K P R+ HTASV+GN M ++GG N T H E +C + +
Sbjct: 435 TLKGRDGLQGPRERAFHTASVLGNYMVVYGG-------NVHT--HYQEEKCYEDGIFFYH 485
Query: 291 LDTTEWTT---LVSDSQEDKKNSRPRPRAGHCAVAIGTRLYFWSG 332
L +W + L + + + P R H A +G + +G
Sbjct: 486 LGCHQWVSGAELAPPGTPEGRAAPPSGRYSHVAAVLGGSVLLVAG 530
Score = 46.2 bits (108), Expect = 1e-04
Identities = 31/92 (33%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
Query: 184 GVVPSPRESHTAVIYCKKDSGSPKMYVFGGM-CGARLDDLWQLDLETMSWSKPETKGTVP 242
G PSPR H A +G MY+ GG+ G D W L+L T+ W + + TV
Sbjct: 1493 GPGPSPRSFHAAAYV---PAGRGAMYLLGGLTAGGVTRDFWVLNLTTLQWRQEKAPQTVE 1549
Query: 243 LPR-SLHTASV-IGNKMYIFGGWVPHKGENTE 272
LP + HT + G + + GG+ P G N +
Sbjct: 1550 LPAVAGHTLTARRGLSLLLVGGYSPENGFNQQ 1581
Score = 33.5 bits (75), Expect = 0.79
Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 7/77 (9%)
Query: 20 PRARHGHRAVAIRELMIIFGGGN--EGIADELHVYNTATNQWFLPAVRGDIPPG-----C 72
PR R H + + + M++ GG + + + ++ +Y N W LP + G
Sbjct: 1715 PRPRLFHASALLGDTMVVLGGRSDPDEFSSDVLLYQVNCNAWLLPDLTRSASVGPPMEES 1774
Query: 73 AAHGFVCDGTRILVFGG 89
AH G+R+ + GG
Sbjct: 1775 VAHAVAAVGSRLYISGG 1791
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 50.1 bits (118), Expect = 8e-06
Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSWEPPT 701
L P + Y+ + +NG G GP S+ EF T G P AP R+ + N+E I+L W+ P
Sbjct: 894 LFPYSNYKLEMVVVNGRGDGPRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPE 952
Query: 702 SPSGNILEYS-AYLAIRTAQI 721
P+G ++ Y+ Y+A ++
Sbjct: 953 HPNGIMIGYTLKYVAFNGTKV 973
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 50.1 bits (118), Expect = 8e-06
Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSWEPPT 701
L P + Y+ + +NG G GP S+ EF T G P AP R+ + N+E I+L W+ P
Sbjct: 909 LFPYSNYKLEMVVVNGRGDGPRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPE 967
Query: 702 SPSGNILEYS-AYLAIRTAQI 721
P+G ++ Y+ Y+A ++
Sbjct: 968 HPNGIMIGYTLKYVAFNGTKV 988
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 50.1 bits (118), Expect = 8e-06
Identities = 28/81 (34%), Positives = 45/81 (55%), Gaps = 3/81 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSWEPPT 701
L P + Y+ + +NG G GP S+ EF T G P AP R+ + N+E I+L W+ P
Sbjct: 894 LFPYSNYKLEMVVVNGRGDGPRSETKEF-TTPEGVPSAPRRFRVRQPNLETINLEWDHPE 952
Query: 702 SPSGNILEYS-AYLAIRTAQI 721
P+G ++ Y+ Y+A ++
Sbjct: 953 HPNGIMIGYTLKYVAFNGTKV 973
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 50.1 bits (118), Expect = 8e-06
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 44/208 (21%)
Query: 533 SSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETH-------ATATPFSKET-- 583
SS N V K +TS TT+ V T A K R++T A + K T
Sbjct: 22271 SSINNYIVEKRDTSTTTWQI---VSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYL 22327
Query: 584 ----------------PSNPVATVKAG---ERQWCDVGIFKNNTALVSQFYLLPKGKQSI 624
P PV T+ + E QW + + + V ++L K + SI
Sbjct: 22328 NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP--ISDGGSRVIGYHLERKERNSI 22385
Query: 625 S--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFP 678
K+ +P + K L G Y FRV+A N GIG SK+SE C P P
Sbjct: 22386 LWVKLNKTPIPQ-TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP--P 22442
Query: 679 GAPSAVRISKNVEGIHLSWEPPTSPSGN 706
G P A+ +++N + L W+ PT G+
Sbjct: 22443 GRPEAIIVTRN--SVTLQWKKPTYDGGS 22468
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/199 (28%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 536 TNGAVVKDETSLTTFSTKSEVDETYALPATKISR----------VETHATATPFSKETPS 585
T+ V K ETS +S SE E + TKI + V + P ++
Sbjct: 26999 THYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 27058
Query: 586 NPVATVKAGERQWCDVG-IFKNNTALV------------SQFYLLPKGKQSIS--KVGNA 630
A V G +V I KN+ +V S ++L + K+S+ KV
Sbjct: 27059 AKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKE 27118
Query: 631 DVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISK 688
+ D + K L + Y++RV A+N G GPFS+ SEF K P PG P+ +RI+
Sbjct: 27119 TIRD-TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 27177
Query: 689 NVE-GIHLSWEPPTSPSGN 706
+ + I L W P G+
Sbjct: 27178 STKSSITLGWSKPVYDGGS 27196
Score = 43.9 bits (102), Expect = 6e-04
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 30/207 (14%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRV 570
T+V VS+T T + K ++ + E F+ ++ +++AL + I
Sbjct: 23367 TTVWDVVSATVARTTLKVTKLKTGT--------EYQFRIFA-ENRYGQSFALESDPIVAQ 23417
Query: 571 ETHATATPFSKETPSNPVATVKAGER---QWCDVGIFKNNTALVSQFYLLPKGKQSI--S 625
+ P P P AT + + QW + N + V ++L K + SI +
Sbjct: 23418 YPYKEPGP-----PGTPFATAISKDSMVIQWHEP--VNNGGSPVIGYHLERKERNSILWT 23470
Query: 626 KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFPGAP 681
KV + D + K Q+L G Y FRV A N G+G SK SE C P PG P
Sbjct: 23471 KVNKTIIHD-TQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP--PGTP 23527
Query: 682 SAVRISKNVEGIHLSWEPPTSPSGNIL 708
+ + +N I L W P G+++
Sbjct: 23528 EPIMVKRN--EITLQWTKPVYDGGSMI 23552
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGF-PGAPSAVRI-SKNVEGIHLSWEP 699
L+ G Y+FR AIN GIGP S+ S+ + P F PG PS + K I L W+P
Sbjct: 15668 LLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKP 15727
Query: 700 PTSPSGN 706
P G+
Sbjct: 15728 PAKDGGS 15734
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 611 VSQFYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKIS 668
+S + + + K+S+ ++V V + LK L+ G Y+FRV A+N G S+ S
Sbjct: 29271 ISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 29330
Query: 669 EFKTC-----IPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
F +C PG P AP V +K+ I L+W P G
Sbjct: 29331 NFISCREPSYTPGPPSAPRVVDTTKH--SISLAWTKPMYDGG 29370
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 38/215 (17%)
Query: 581 KETPSNPVATVK----AGERQ--WCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPD 634
++TP V ++ GE+ W D + N+ Y++ K + S++ A + D
Sbjct: 28049 QDTPGKVVGPIRFTNITGEKMTLWWDAPL--NDGCAPITHYIIEK--RETSRLAWALIED 28104
Query: 635 ------YSLLKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAV 684
Y+ +K L+ G Y+FRV+A+N G+G P +++ + +P PG P
Sbjct: 28105 KCEAQSYTAIK---LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPS 28161
Query: 685 RISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVT 744
I+ N I L+W P S G+ E Y+ R + +++ R +T VT
Sbjct: 28162 NITGN--SITLTWARPESDGGS--EIQQYILERREKKSTRWVKVISKRPIS--ETRFKVT 28215
Query: 745 AGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQV 779
N + F + A+N G GPA+ +
Sbjct: 28216 GLTEGNEY---------EFHVMAENAAGVGPASGI 28241
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 23/200 (11%)
Query: 530 KTESSSTNGAVVKDETSLTTFSTKSEVDET-----------YALPATKISR--VETHATA 576
K E+S TN +V + TTF + V + Y + +S V H
Sbjct: 27696 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 27755
Query: 577 TPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSI--SKVGNADVPD 634
P P T W D ++ + V+ F++ K + SI KV + +
Sbjct: 27756 IPGPPGKPVIYNVTSDGMSLTW-DAPVYDGGSE-VTGFHVEKKERNSILWQKVNTSPISG 27813
Query: 635 YSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEG 692
+ LV G Y+FRV A N G+ S S+F + PG P + +++ E
Sbjct: 27814 REY-RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTR--ET 27870
Query: 693 IHLSWEPPTSPSGN-ILEYS 711
I L W PP G+ I+ YS
Sbjct: 27871 ITLKWNPPLRDGGSKIVGYS 27890
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 614 FYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF- 670
++L K K SI K+ + D + K L G Y F+V+A N GIG SK+SE
Sbjct: 24539 YHLEQKEKNSILWVKLNKTPIQD-TKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 24597
Query: 671 ---KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
C P PG P A+ I++N + L W+ P G+
Sbjct: 24598 VARDPCDP--PGRPEAIVITRN--NVTLKWKKPAYDGGS 24632
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHL 695
Q L+ G Y FR+AA N G+GPF + SE +P P ++KN + L
Sbjct: 16678 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNT--VTL 16735
Query: 696 SWEPPTSPSGN-ILEY 710
+W PP G+ I+ Y
Sbjct: 16736 TWNPPKYDGGSEIINY 16751
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L G Y+FRV A N G+GP ++ + +PG PG P ++K + +
Sbjct: 21219 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTK--DSMT 21276
Query: 695 LSWEPPTSPSGN-ILEY 710
+SW P S G+ IL Y
Sbjct: 21277 ISWHEPLSDGGSPILGY 21293
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L+ G+ Y+FRV AIN G+GP S S+ T PG P L
Sbjct: 16381 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLE 16440
Query: 697 WEPPTSPSGN-----ILEY 710
W PP G+ I+EY
Sbjct: 16441 WSPPLKDGGSKVTGYIVEY 16459
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPF--SKISEFKTCIPGFPGAPSAVRI-SKNVEG 692
S K L G Y FRVAA N GIG + S++ E ++ I PG P ++I + +G
Sbjct: 29889 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI-RIPGPPETLQIFDVSRDG 29947
Query: 693 IHLSWEPPTSPSGN 706
+ L+W PP G+
Sbjct: 29948 MTLTWYPPEDDGGS 29961
Score = 39.7 bits (91), Expect = 0.011
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 615 YLLPKGKQSISK----VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG---PFSKI 667
Y+L K ++++SK V + Y+ + DL+ G Y FRV+A N GIG P SK
Sbjct: 17045 YILEK-RETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 17103
Query: 668 SEFKTCI--PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN-ILEY 710
K I P P P A+ + N + L+W+PP G+ IL Y
Sbjct: 17104 VFAKDPIAKPSPPVNPEAIDTTCN--SVDLTWQPPRHDGGSKILGY 17147
Score = 38.5 bits (88), Expect = 0.025
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 34/147 (23%)
Query: 643 LVPGTGYRFRVAAINGCGIG------PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
L+ G Y FRV+A+N G G P + F PG P P ++KN + S
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGP--PGPPEKPEVSNVTKNTATV--S 20591
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTS-----CIVTAGQLANA 751
W+ P G+ E + Y R + +R +KT C VT Q +
Sbjct: 20592 WKRPVDDGGS--EITGYHVERREKKS--------LRWVRAIKTPVSDLRCKVTGLQEGST 20641
Query: 752 HIDYTSRPAIVFRISAKNEKGYGPATQ 778
+ FR+SA+N G GP ++
Sbjct: 20642 Y---------EFRVSAENRAGIGPPSE 20659
Score = 37.7 bits (86), Expect = 0.042
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 25/145 (17%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISKNVE-GIHLSWE 698
D+V G Y FRV A N G+G S + F K P P P + S + + L WE
Sbjct: 13254 DVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWE 13313
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLK----TSCIVTAGQLANAHID 754
PP G+ + Y+ R + +DN I C +K + VT + N ++
Sbjct: 13314 PPLKDGGSPI--LGYIIERCEEGKDN-------WIRCNMKLVPELTYKVTGLEKGNKYL- 13363
Query: 755 YTSRPAIVFRISAKNEKGYGPATQV 779
+R+SA+N+ G +++
Sbjct: 13364 --------YRVSAENKAGVSDPSEI 13380
Score = 37.7 bits (86), Expect = 0.042
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGFPGAPSAVRIS-KNVEGIHLSWEPP 700
L+ G Y FRV A N G G FS S+ KT P P P R++ + I L WEPP
Sbjct: 14966 LLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPP 15025
Query: 701 T-SPSGNILEY 710
+ G I+ Y
Sbjct: 15026 AFNGGGEIVGY 15036
Score = 37.7 bits (86), Expect = 0.042
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVE-GIHL 695
K L G Y F V A N G+GP S IS C PG P+ V+++ + + L
Sbjct: 28213 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSL 28272
Query: 696 SWEPPTSPSG 705
W P G
Sbjct: 28273 EWSKPVFDGG 28282
Score = 37.4 bits (85), Expect = 0.055
Identities = 50/230 (21%), Positives = 97/230 (42%), Gaps = 26/230 (11%)
Query: 495 VGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKS 554
+ + + D++ +PE S + T +V ++ ++ + T VKD T T+
Sbjct: 14093 INITKNTADLKWTVPEKDGGSPI--TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 14150
Query: 555 E-----VDETYALPATKISRVETHATATP-FSKETPSNPVATVKAGER----QWCDVGIF 604
V A+ + + +E A F+ P +A V +R +W
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP--- 14207
Query: 605 KNNTALVSQFYLLPKGKQSIS---KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGI 661
KN+ Q Y++ K ++ + K G PD + + D++ GT +F+V A N G+
Sbjct: 14208 KNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF-RVTDVIEGTEVQFQVRAENEAGV 14266
Query: 662 GPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHLSWEPPTSPSGN 706
G S+ +E + P +P + + +V + I ++W+PP G+
Sbjct: 14267 GHPSEPTEILSIED--PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 14314
Score = 37.4 bits (85), Expect = 0.055
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSK----ISEFKTCIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FRV A N G GP ++ I++ K PG P P ++SK E + + W
Sbjct: 18360 LIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK--EEMTVVWN 18417
Query: 699 PPTSPSG 705
PP G
Sbjct: 18418 PPEYDGG 18424
Score = 37.4 bits (85), Expect = 0.055
Identities = 39/135 (28%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 649 YRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVE-GIHLSWEPPTSPSG 705
Y FRV+A N G+G P +K C P F PG P+ I + I L+W P G
Sbjct: 23889 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 23948
Query: 706 N-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFR 764
+ IL Y + + + Q+V +T VT +++ T R
Sbjct: 23949 SEILGY----VVEICKADEEEWQIVTP------QTGLRVTRFEISK----LTEHQEYKIR 23994
Query: 765 ISAKNEKGYGPATQV 779
+ A N+ G G AT V
Sbjct: 23995 VCALNKVGLGEATSV 24009
Score = 37.4 bits (85), Expect = 0.055
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGI------GPFSKISEFKTCIPGFPGAPSAVRISKNVEG 692
K L+PG Y FRV A+N GI GP + + +K PG P P I+K +
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITK--DS 24917
Query: 693 IHLSWEPPTSPSGNILE 709
+ ++W P G +E
Sbjct: 24918 MVVTWARPVDDGGTEIE 24934
Score = 37.4 bits (85), Expect = 0.055
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 20/141 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVEGIHLSWE 698
++L G Y FRV A N GIG P K P PG + V +++N I WE
Sbjct: 25260 ENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI--KWE 25317
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P S G+ + + Y+ ++Q S+ K S L T+
Sbjct: 25318 KPESDGGS--KITGYV----VEMQTKGSE----------KWSTCTQVKTLEATISGLTAG 25361
Query: 759 PAIVFRISAKNEKGYGPATQV 779
VFR++A NEKG Q+
Sbjct: 25362 EEYVFRVAAVNEKGRSDPRQL 25382
Score = 37.0 bits (84), Expect = 0.072
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 27/140 (19%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISE-------FKTCIPGFPGAPSAVRISKNVEGIHL 695
L G+ Y FRVAA N G +++I + F T PG P A + V ++K + L
Sbjct: 14147 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PGPPYALAVVDVTKR--HVDL 14202
Query: 696 SWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WEPP + G ++ + + +L + G TAG N + D
Sbjct: 14203 KWEPPKNDGGRPIQ---------RYVIEKKERLGTRWVKAG------KTAGPDCNFRVTD 14247
Query: 755 YTSRPAIVFRISAKNEKGYG 774
+ F++ A+NE G G
Sbjct: 14248 VIEGTEVQFQVRAENEAGVG 14267
Score = 36.6 bits (83), Expect = 0.094
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQD---LVPGTGYRFRVAAINGCGIGPFSK----I 667
Y++ K S K +V + ++ K+ L+P Y FRV A+N GI K +
Sbjct: 15532 YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 15591
Query: 668 SEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
+ +PG PG P + +K + +SW PP G+
Sbjct: 15592 IQDPYRLPGPPGKPKVLARTKG--SMLVSWTPPLDNGGS 15628
Score = 36.6 bits (83), Expect = 0.094
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLSW 697
LVP Y+FR+ A N G+ S SE C P PG + ISK + + L W
Sbjct: 30394 LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK--DSVTLQW 30451
Query: 698 EPPTSPSG-NILEY 710
E P G IL Y
Sbjct: 30452 EKPECDGGKEILGY 30465
Score = 36.2 bits (82), Expect = 0.12
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IP-GFPGAPSAVRISKNVEGIHLSWEPP 700
LV G Y FR+ A+N G P SK +E+ T +P PG P + ++K+ + L W P
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST--VSLIWARP 19213
Query: 701 TSPSGN 706
G+
Sbjct: 19214 KHDGGS 19219
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 646 GTGYRFRVAAINGCGIG-------PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSW 697
G Y FRV+A N G G P S++ PG P V I+ N G+ L+W
Sbjct: 13157 GVEYLFRVSARNRVGTGEPVETDNPVEARSKYDV-----PGPPLNVTITDVNRFGVSLTW 13211
Query: 698 EPPTSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
EPP G I Y L +T+ D T+ V A L+ D
Sbjct: 13212 EPPEYDGGAEITNYVIELRDKTSIRWD---------------TAMTVRAEDLSATVTDVV 13256
Query: 757 SRPAIVFRISAKNEKGYG 774
FR+ A+N G G
Sbjct: 13257 EGQEYSFRVRAQNRIGVG 13274
Score = 35.8 bits (81), Expect = 0.16
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISK-NVEGIHLSWEPP 700
L+PG Y FRV A N GI + P G P P R++K N + I ++W+ P
Sbjct: 19056 LIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP 19115
Query: 701 TSPSGN 706
S G+
Sbjct: 19116 DSDGGS 19121
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L G Y FRV AIN G+G S SE + PG P + I++N + L
Sbjct: 20236 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRN--SVTLI 20293
Query: 697 WEPPTSPSGNIL 708
W P G+ L
Sbjct: 20294 WTEPKYDGGHKL 20305
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTC----IPGFPGAPSAVRISKNVEG 692
L+ L G Y FRVAA N G+G S+ S F + C PG P P S++
Sbjct: 24961 LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS--S 25018
Query: 693 IHLSWEPPTSPSG 705
+ L+W P G
Sbjct: 25019 VSLAWSKPIYDGG 25031
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLS 696
+L GY FRV+A N GI ++S PG PG P+ ++K + ++
Sbjct: 30787 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTK--DSCVVA 30844
Query: 697 WEPPTSPSG 705
W+PP S G
Sbjct: 30845 WKPPASDGG 30853
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISE-FKTCIPG-FPGAPSAVR-ISKNVEGIHLSWE 698
DLV G Y F+V A N CG G + + E P P P V+ + I L+W+
Sbjct: 13550 DLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWD 13609
Query: 699 PPTSPSGN 706
PP + G+
Sbjct: 13610 PPKNDGGS 13617
Score = 35.4 bits (80), Expect = 0.21
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L G Y FRV A N G+GP +++ K P PG P I++N +
Sbjct: 17663 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 17722
Query: 694 HLSWEPPTSPSGN 706
SW P S G+
Sbjct: 17723 --SWTLPKSDGGS 17733
Score = 35.4 bits (80), Expect = 0.21
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L+ G Y FR+ A+N G+G P +++ +P P AP ++K + +
Sbjct: 22697 KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTK--DSMI 22754
Query: 695 LSWEPPTSPSGN-ILEY 710
+ WE P S G+ IL Y
Sbjct: 22755 VVWERPASDGGSEILGY 22771
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 18/132 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
DL T + FRV A N GIG P K P +++ S I LSW P
Sbjct: 27428 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSWTKP 27486
Query: 701 TSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPA 760
G+++ + Y+ R + + S + G+ +C + QL +
Sbjct: 27487 DFDGGSVI--TEYVVERKGKGEQTWS-------HAGISKTCEIEVSQLKEQSV------- 27530
Query: 761 IVFRISAKNEKG 772
+ FR+ AKNEKG
Sbjct: 27531 LEFRVFAKNEKG 27542
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGP-FSKISEFKTCIPGFPGAPSAVR----ISKNVEGIHLS 696
DL+ Y FRV A N GIGP I P +P P I+KN +HLS
Sbjct: 15974 DLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT--VHLS 16031
Query: 697 WEPPTSPSGN 706
W+PP + G+
Sbjct: 16032 WKPPKNDGGS 16041
Score = 34.7 bits (78), Expect = 0.36
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 34/243 (13%)
Query: 502 LDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVV-KDETSLTTFSTKSEVDETY 560
LDV +S+ + T+ ++ S ++ K ETS ++ SE ++
Sbjct: 20470 LDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSC 20529
Query: 561 ALPATKISRVETH----ATATPFSKETP--SNPVATVKA----GERQWCDVGIFKNNTAL 610
ATK+ + + + + K P S PV V G + +V NTA
Sbjct: 20530 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTAT 20589
Query: 611 VSQ-------------FYLLPKGKQSISKVGNADVPDYSL-LKKQDLVPGTGYRFRVAAI 656
VS +++ + K+S+ V P L K L G+ Y FRV+A
Sbjct: 20590 VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 20649
Query: 657 NGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYS 711
N GIGP S+ S+ PG P P +K + L+W P G LE +
Sbjct: 20650 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTK--KSASLAWGKPHYDGG--LEIT 20705
Query: 712 AYL 714
Y+
Sbjct: 20706 GYV 20708
Score = 34.3 bits (77), Expect = 0.46
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 24/138 (17%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLS 696
K ++L G Y FRV A N G+G P + K P P P V ++ + L
Sbjct: 24175 KVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--PSPPGKVTLTDVSQTSASLM 24232
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WE P G+ +L Y + + G + IV ++ NA +
Sbjct: 24233 WEKPEHDGGSRVLGYVVEMQPK------------------GTEKWSIVAESKVCNAVVTG 24274
Query: 755 YTSRPAIVFRISAKNEKG 772
+S FR+ A NEKG
Sbjct: 24275 LSSGQEYQFRVKAYNEKG 24292
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 24/180 (13%)
Query: 611 VSQFYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PF 664
++ ++L K K S V + +P+ + K Q+L+P Y+FRV A N GIG P
Sbjct: 18427 ITGYFLEKKEKHSTRWVPVNKSAIPERRM-KVQNLLPDHEYQFRVKAENEIGIGEPSLPS 18485
Query: 665 SKISEFKTCIPGFPGAPSAVRISKNVE-GIHLSWEPPTSPSGNILEYSAYLAIRTAQIQD 723
+ P PG P+ R+ + I L W P G Y+ +I D
Sbjct: 18486 RPVVAKDPIEP--PGPPTNFRVVDTTKHSITLGWGKPVYDGG--APIIGYVVEMRPKIAD 18541
Query: 724 NPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTS---RPAIVFRISAKNEKGYGPATQVR 780
+ R C A QL TS FR+ A+N+ G G +++
Sbjct: 18542 ASPDEGWKR--CN-------AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK 18592
Score = 33.9 bits (76), Expect = 0.61
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 22/137 (16%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTC-IPGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG P K +P PG + +++N + LS
Sbjct: 23093 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRN--SVSLS 23150
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P G+ I++Y +V M+ K S L +
Sbjct: 23151 WTKPEHDGGSKIIQY-----------------IVEMQAKHSEKWSECARVKSLQAVITNL 23193
Query: 756 TSRPAIVFRISAKNEKG 772
T +FR+ A NEKG
Sbjct: 23194 TQGEEYLFRVVAVNEKG 23210
Score = 33.5 bits (75), Expect = 0.79
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISKNVEG-IHLSWEPP 700
L+ G Y+FRV A N G GP +I P G P +P + ++ + I L W+ P
Sbjct: 15259 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 15318
Query: 701 TSPSGNILE 709
S G+ ++
Sbjct: 15319 RSNGGSPIQ 15327
Score = 33.5 bits (75), Expect = 0.79
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 651 FRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-EGIHLSWEPPTSPSGNILE 709
+ + A N G SK + K + PG P++V+I+K + LSWEPP G+ E
Sbjct: 19366 YTITAENSSG----SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS--E 19419
Query: 710 YSAYLAIRTAQIQDNPSQL-VFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAK 768
+ Y+ + + N +Q+ + I TSC V +L H +Y FRI A+
Sbjct: 19420 ITNYIVDKRETSRPNWAQVSATVPI-----TSCSVE--KLIEGH-EYQ------FRICAE 19465
Query: 769 NEKGYG 774
N+ G G
Sbjct: 19466 NKYGVG 19471
Score = 33.5 bits (75), Expect = 0.79
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRI-SKNVEGIHLS 696
K L+ G Y FRV +N G+G + K P P P+++ I S E + L
Sbjct: 25943 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLC 26002
Query: 697 WEPPTSPSGNILEYSAYLAIR 717
W P S G+ E S Y+ R
Sbjct: 26003 WSRPESDGGS--EISGYIIER 26021
Score = 33.1 bits (74), Expect = 1.0
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEG 692
LK L GT Y FRV AIN G G S S+ PG P P +++
Sbjct: 19547 LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRS--S 19604
Query: 693 IHLSWEPPTSPSGN 706
+ LSW P G+
Sbjct: 19605 VSLSWGKPAYDGGS 19618
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI--PGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG ++ +E P PG + + +++N + LS
Sbjct: 22011 KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRN--SVSLS 22068
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
WE P G+ Y+ + D + +++ T +T G +
Sbjct: 22069 WEKPEHDGGS--RILGYIVEMQTKGSDKWATCATVKV-----TEATIT-GLIQGEEYS-- 22118
Query: 757 SRPAIVFRISAKNEKGYGPATQV 779
FR+SA+NEKG Q+
Sbjct: 22119 ------FRVSAQNEKGISDPRQL 22135
Score = 33.1 bits (74), Expect = 1.0
Identities = 65/270 (24%), Positives = 98/270 (36%), Gaps = 46/270 (17%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDE---TYALPATKI 567
T VS+TV+ T V + T E +K E F +D T LP T
Sbjct: 26618 TEVSATVARTMMKVMKLTTGEEYQFR----IKAENR---FGISDHIDSACVTVKLPYT-- 26668
Query: 568 SRVETHATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSIS-K 626
TP TP T ++ W + N + V ++L K + SI +
Sbjct: 26669 ---------TPGPPSTPWVTNVTRESITVGWHEP--VSNGGSAVVGYHLEMKDRNSILWQ 26717
Query: 627 VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PFSKISEFKTCIPGFPGAPS 682
N V + K + G Y FRV A N G+G P + C P P
Sbjct: 26718 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP--PRNVR 26775
Query: 683 AVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCI 742
ISKN + LSW+ P G+ + + Y+ R +D P + + +
Sbjct: 26776 ITDISKN--SVSLSWQQPAFDGGS--KITGYIVER----RDLPDGRWTKASFTNVTETQF 26827
Query: 743 VTAGQLANAHIDYTSRPAIVFRISAKNEKG 772
+ +G N+ + FR+ A+N G
Sbjct: 26828 IISGLTQNSQYE--------FRVFARNAVG 26849
Score = 33.1 bits (74), Expect = 1.0
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572
V+S+V TQ VT T E S F SE + P +
Sbjct: 28791 VNSSVKRTQIKVTHLTKYMEYS---------------FRVSSENRFGVSKPLESAPIIAE 28835
Query: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADV 632
H P + P + A +W + + + + + +++ K + +I V V
Sbjct: 28836 HPFVPPSAPTRPEVYHVSANAMSIRWEEP--YHDGGSKIIGYWVEKKERNTILWVKENKV 28893
Query: 633 PDYSL-LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPG-----FPGAPSAVRI 686
P K LV G Y+FR A+N G+ SK SE I PG P +
Sbjct: 28894 PCLECNYKVTGLVEGLEYQFRTYALNAAGV---SKASEASRPIMAQNPVDAPGRPEVTDV 28950
Query: 687 SKNVEGIHLSWEPPTSPSGN 706
+++ + L W P G+
Sbjct: 28951 TRST--VSLIWSAPAYDGGS 28968
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/54 (29%), Positives = 27/54 (50%)
Query: 616 LLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE 669
+ P G + +V + + D ++ +VP Y RV A+N G+ S+ISE
Sbjct: 14323 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 14376
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 26/144 (18%)
Query: 643 LVPGTGYRFRVAAINGCGIG-PFSKISEFKT---CIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FR+ A N GIG P E +PG P P+ +++N + ++WE
Sbjct: 16281 LLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRN--SMTVNWE 16338
Query: 699 PPT----SP-SGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
P SP +G LE + R ++ +P + M + K + ++
Sbjct: 16339 EPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDP--IKAMTLGVSYKVTGLIEGS------- 16389
Query: 754 DYTSRPAIVFRISAKNEKGYGPAT 777
DY FR+ A N G GPA+
Sbjct: 16390 DYQ------FRVYAINAAGVGPAS 16407
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 18/139 (12%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGI 693
+L + LV GT Y FRV N GIG + S+ + +P P V ++K+ +
Sbjct: 29594 TLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST--V 29651
Query: 694 HLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
L+WE P G+ L A + + +M++ LK + + N
Sbjct: 29652 TLAWEKPLYDGGSRLTGYVLEACKAGTER-------WMKVVT-LKPTVLEHTVTSLNEGE 29703
Query: 754 DYTSRPAIVFRISAKNEKG 772
Y +FRI A+NEKG
Sbjct: 29704 QY------LFRIRAQNEKG 29716
Score = 31.6 bits (70), Expect = 3.0
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF-----PGAPSAVRIS-KNVE 691
L K +L+ Y FRV A N G+GP E KT I PG P + I+ K
Sbjct: 18059 LIKANLLANNEYYFRVCAENKVGVGP---TIETKTPILAINPIDRPGEPENLHIADKGKT 18115
Query: 692 GIHLSWEPPTSPSGN 706
++L W P G+
Sbjct: 18116 FVYLKWRRPDYDGGS 18130
Score = 31.6 bits (70), Expect = 3.0
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
Query: 614 FYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE-- 669
++L K + SI SK + D + +K L G Y +RV A N GIG SK E
Sbjct: 25621 YHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 25679
Query: 670 --FKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
C P PG P I++ + + L W P G
Sbjct: 25680 PARDPCDP--PGQPEVTNITR--KSVSLKWSKPHYDGG 25713
Score = 30.8 bits (68), Expect = 5.1
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHL 695
+DL+P Y FRV A+N G G + ++ I P P + V E + +
Sbjct: 14541 KDLIPNGEYFFRVKAVNKVGGGEYIELK--NPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 14598
Query: 696 SWEPPTSPSGN 706
+W+PP G+
Sbjct: 14599 TWKPPLYDGGS 14609
Score = 30.8 bits (68), Expect = 5.1
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 20/139 (14%)
Query: 637 LLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGIH 694
+ K DL G Y FRV+A+N G+G ++ E T P P V SK+
Sbjct: 28506 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKS--SAV 28563
Query: 695 LSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHID 754
L+W P G+ + YL + D + G T +L
Sbjct: 28564 LAWLKPDHDGGS--RITGYLLEMRQKGSD-------FWVEAGHTKQLTFTVERL------ 28608
Query: 755 YTSRPAIVFRISAKNEKGY 773
+ FR+ AKN+ GY
Sbjct: 28609 -VEKTEYEFRVKAKNDAGY 28626
Score = 30.4 bits (67), Expect = 6.7
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-----PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
+LVPG Y FRV A+N G G P ++ P P ++KN L+
Sbjct: 18761 NLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN--SATLA 18818
Query: 697 WEPPTSPSG 705
W PP G
Sbjct: 18819 WLPPLRDGG 18827
Score = 30.4 bits (67), Expect = 6.7
Identities = 39/151 (25%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
+L G Y FRV A N GIG P K P VR S + + W+ P
Sbjct: 19849 NLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVR-SVSKSSCSIGWKKP 19907
Query: 701 TSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S G+ I+ Y + ++N Q V + L + D T
Sbjct: 19908 HSDGGSRIIGY-----VVDFLTEENKWQRVMKSL-------------SLQYSAKDLTEGK 19949
Query: 760 AIVFRISAKNEKGYGPATQVRWLQGNNKKAP 790
FR+SA+NE G G +++ + ++ AP
Sbjct: 19950 EYTFRVSAENENGEGTPSEITVVARDDVVAP 19980
Score = 30.4 bits (67), Expect = 6.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L+ G Y FR+ A+N G+G P + + +PG P + I+K + +
Sbjct: 23778 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK--DSM 23835
Query: 694 HLSWEPPTSPSGN 706
+ W P S G+
Sbjct: 23836 TVCWNRPDSDGGS 23848
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 50.1 bits (118), Expect = 8e-06
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 44/208 (21%)
Query: 533 SSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETH-------ATATPFSKET-- 583
SS N V K +TS TT+ V T A K R++T A + K T
Sbjct: 15966 SSINNYIVEKRDTSTTTWQI---VSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYL 16022
Query: 584 ----------------PSNPVATVKAG---ERQWCDVGIFKNNTALVSQFYLLPKGKQSI 624
P PV T+ + E QW + + + V ++L K + SI
Sbjct: 16023 NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP--ISDGGSRVIGYHLERKERNSI 16080
Query: 625 S--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFP 678
K+ +P + K L G Y FRV+A N GIG SK+SE C P P
Sbjct: 16081 LWVKLNKTPIPQ-TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP--P 16137
Query: 679 GAPSAVRISKNVEGIHLSWEPPTSPSGN 706
G P A+ +++N + L W+ PT G+
Sbjct: 16138 GRPEAIIVTRN--SVTLQWKKPTYDGGS 16163
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/199 (28%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 536 TNGAVVKDETSLTTFSTKSEVDETYALPATKISR----------VETHATATPFSKETPS 585
T+ V K ETS +S SE E + TKI + V + P ++
Sbjct: 20694 THYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 20753
Query: 586 NPVATVKAGERQWCDVG-IFKNNTALV------------SQFYLLPKGKQSIS--KVGNA 630
A V G +V I KN+ +V S ++L + K+S+ KV
Sbjct: 20754 AKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKE 20813
Query: 631 DVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISK 688
+ D + K L + Y++RV A+N G GPFS+ SEF K P PG P+ +RI+
Sbjct: 20814 TIRD-TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20872
Query: 689 NVE-GIHLSWEPPTSPSGN 706
+ + I L W P G+
Sbjct: 20873 STKSSITLGWSKPVYDGGS 20891
Score = 43.9 bits (102), Expect = 6e-04
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 30/207 (14%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRV 570
T+V VS+T T + K ++ + E F+ ++ +++AL + I
Sbjct: 17062 TTVWDVVSATVARTTLKVTKLKTGT--------EYQFRIFA-ENRYGQSFALESDPIVAQ 17112
Query: 571 ETHATATPFSKETPSNPVATVKAGER---QWCDVGIFKNNTALVSQFYLLPKGKQSI--S 625
+ P P P AT + + QW + N + V ++L K + SI +
Sbjct: 17113 YPYKEPGP-----PGTPFATAISKDSMVIQWHEP--VNNGGSPVIGYHLERKERNSILWT 17165
Query: 626 KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFPGAP 681
KV + D + K Q+L G Y FRV A N G+G SK SE C P PG P
Sbjct: 17166 KVNKTIIHD-TQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP--PGTP 17222
Query: 682 SAVRISKNVEGIHLSWEPPTSPSGNIL 708
+ + +N I L W P G+++
Sbjct: 17223 EPIMVKRN--EITLQWTKPVYDGGSMI 17247
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGF-PGAPSAVRI-SKNVEGIHLSWEP 699
L+ G Y+FR AIN GIGP S+ S+ + P F PG PS + K I L W+P
Sbjct: 9363 LLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKP 9422
Query: 700 PTSPSGN 706
P G+
Sbjct: 9423 PAKDGGS 9429
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 611 VSQFYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKIS 668
+S + + + K+S+ ++V V + LK L+ G Y+FRV A+N G S+ S
Sbjct: 22966 ISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 23025
Query: 669 EFKTC-----IPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
F +C PG P AP V +K+ I L+W P G
Sbjct: 23026 NFISCREPSYTPGPPSAPRVVDTTKH--SISLAWTKPMYDGG 23065
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 38/215 (17%)
Query: 581 KETPSNPVATVK----AGERQ--WCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPD 634
++TP V ++ GE+ W D + N+ Y++ K + S++ A + D
Sbjct: 21744 QDTPGKVVGPIRFTNITGEKMTLWWDAPL--NDGCAPITHYIIEK--RETSRLAWALIED 21799
Query: 635 ------YSLLKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAV 684
Y+ +K L+ G Y+FRV+A+N G+G P +++ + +P PG P
Sbjct: 21800 KCEAQSYTAIK---LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPS 21856
Query: 685 RISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVT 744
I+ N I L+W P S G+ E Y+ R + +++ R +T VT
Sbjct: 21857 NITGN--SITLTWARPESDGGS--EIQQYILERREKKSTRWVKVISKRPIS--ETRFKVT 21910
Query: 745 AGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQV 779
N + F + A+N G GPA+ +
Sbjct: 21911 GLTEGNEY---------EFHVMAENAAGVGPASGI 21936
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 23/200 (11%)
Query: 530 KTESSSTNGAVVKDETSLTTFSTKSEVDET-----------YALPATKISR--VETHATA 576
K E+S TN +V + TTF + V + Y + +S V H
Sbjct: 21391 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21450
Query: 577 TPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSI--SKVGNADVPD 634
P P T W D ++ + V+ F++ K + SI KV + +
Sbjct: 21451 IPGPPGKPVIYNVTSDGMSLTW-DAPVYDGGSE-VTGFHVEKKERNSILWQKVNTSPISG 21508
Query: 635 YSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEG 692
+ LV G Y+FRV A N G+ S S+F + PG P + +++ E
Sbjct: 21509 REY-RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTR--ET 21565
Query: 693 IHLSWEPPTSPSGN-ILEYS 711
I L W PP G+ I+ YS
Sbjct: 21566 ITLKWNPPLRDGGSKIVGYS 21585
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 614 FYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF- 670
++L K K SI K+ + D + K L G Y F+V+A N GIG SK+SE
Sbjct: 18234 YHLEQKEKNSILWVKLNKTPIQD-TKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 18292
Query: 671 ---KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
C P PG P A+ I++N + L W+ P G+
Sbjct: 18293 VARDPCDP--PGRPEAIVITRN--NVTLKWKKPAYDGGS 18327
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHL 695
Q L+ G Y FR+AA N G+GPF + SE +P P ++KN + L
Sbjct: 10373 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNT--VTL 10430
Query: 696 SWEPPTSPSGN-ILEY 710
+W PP G+ I+ Y
Sbjct: 10431 TWNPPKYDGGSEIINY 10446
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L G Y+FRV A N G+GP ++ + +PG PG P ++K + +
Sbjct: 14914 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTK--DSMT 14971
Query: 695 LSWEPPTSPSGN-ILEY 710
+SW P S G+ IL Y
Sbjct: 14972 ISWHEPLSDGGSPILGY 14988
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L+ G+ Y+FRV AIN G+GP S S+ T PG P L
Sbjct: 10076 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLE 10135
Query: 697 WEPPTSPSGN-----ILEY 710
W PP G+ I+EY
Sbjct: 10136 WSPPLKDGGSKVTGYIVEY 10154
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPF--SKISEFKTCIPGFPGAPSAVRI-SKNVEG 692
S K L G Y FRVAA N GIG + S++ E ++ I PG P ++I + +G
Sbjct: 23584 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI-RIPGPPETLQIFDVSRDG 23642
Query: 693 IHLSWEPPTSPSGN 706
+ L+W PP G+
Sbjct: 23643 MTLTWYPPEDDGGS 23656
Score = 39.7 bits (91), Expect = 0.011
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 615 YLLPKGKQSISK----VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG---PFSKI 667
Y+L K ++++SK V + Y+ + DL+ G Y FRV+A N GIG P SK
Sbjct: 10740 YILEK-RETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10798
Query: 668 SEFKTCI--PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN-ILEY 710
K I P P P A+ + N + L+W+PP G+ IL Y
Sbjct: 10799 VFAKDPIAKPSPPVNPEAIDTTCN--SVDLTWQPPRHDGGSKILGY 10842
Score = 38.5 bits (88), Expect = 0.025
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 34/147 (23%)
Query: 643 LVPGTGYRFRVAAINGCGIG------PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
L+ G Y FRV+A+N G G P + F PG P P ++KN + S
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGP--PGPPEKPEVSNVTKNTATV--S 14286
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTS-----CIVTAGQLANA 751
W+ P G+ E + Y R + +R +KT C VT Q +
Sbjct: 14287 WKRPVDDGGS--EITGYHVERREKKS--------LRWVRAIKTPVSDLRCKVTGLQEGST 14336
Query: 752 HIDYTSRPAIVFRISAKNEKGYGPATQ 778
+ FR+SA+N G GP ++
Sbjct: 14337 Y---------EFRVSAENRAGIGPPSE 14354
Score = 37.7 bits (86), Expect = 0.042
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 25/145 (17%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISKNVE-GIHLSWE 698
D+V G Y FRV A N G+G S + F K P P P + S + + L WE
Sbjct: 6949 DVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWE 7008
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLK----TSCIVTAGQLANAHID 754
PP G+ + Y+ R + +DN I C +K + VT + N ++
Sbjct: 7009 PPLKDGGSPI--LGYIIERCEEGKDN-------WIRCNMKLVPELTYKVTGLEKGNKYL- 7058
Query: 755 YTSRPAIVFRISAKNEKGYGPATQV 779
+R+SA+N+ G +++
Sbjct: 7059 --------YRVSAENKAGVSDPSEI 7075
Score = 37.7 bits (86), Expect = 0.042
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGFPGAPSAVRIS-KNVEGIHLSWEPP 700
L+ G Y FRV A N G G FS S+ KT P P P R++ + I L WEPP
Sbjct: 8661 LLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPP 8720
Query: 701 T-SPSGNILEY 710
+ G I+ Y
Sbjct: 8721 AFNGGGEIVGY 8731
Score = 37.7 bits (86), Expect = 0.042
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVE-GIHL 695
K L G Y F V A N G+GP S IS C PG P+ V+++ + + L
Sbjct: 21908 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSL 21967
Query: 696 SWEPPTSPSG 705
W P G
Sbjct: 21968 EWSKPVFDGG 21977
Score = 37.4 bits (85), Expect = 0.055
Identities = 50/230 (21%), Positives = 97/230 (42%), Gaps = 26/230 (11%)
Query: 495 VGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKS 554
+ + + D++ +PE S + T +V ++ ++ + T VKD T T+
Sbjct: 7788 INITKNTADLKWTVPEKDGGSPI--TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7845
Query: 555 E-----VDETYALPATKISRVETHATATP-FSKETPSNPVATVKAGER----QWCDVGIF 604
V A+ + + +E A F+ P +A V +R +W
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP--- 7902
Query: 605 KNNTALVSQFYLLPKGKQSIS---KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGI 661
KN+ Q Y++ K ++ + K G PD + + D++ GT +F+V A N G+
Sbjct: 7903 KNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF-RVTDVIEGTEVQFQVRAENEAGV 7961
Query: 662 GPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHLSWEPPTSPSGN 706
G S+ +E + P +P + + +V + I ++W+PP G+
Sbjct: 7962 GHPSEPTEILSIED--PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 8009
Score = 37.4 bits (85), Expect = 0.055
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSK----ISEFKTCIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FRV A N G GP ++ I++ K PG P P ++SK E + + W
Sbjct: 12055 LIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK--EEMTVVWN 12112
Query: 699 PPTSPSG 705
PP G
Sbjct: 12113 PPEYDGG 12119
Score = 37.4 bits (85), Expect = 0.055
Identities = 39/135 (28%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 649 YRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVE-GIHLSWEPPTSPSG 705
Y FRV+A N G+G P +K C P F PG P+ I + I L+W P G
Sbjct: 17584 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17643
Query: 706 N-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFR 764
+ IL Y + + + Q+V +T VT +++ T R
Sbjct: 17644 SEILGY----VVEICKADEEEWQIVTP------QTGLRVTRFEISK----LTEHQEYKIR 17689
Query: 765 ISAKNEKGYGPATQV 779
+ A N+ G G AT V
Sbjct: 17690 VCALNKVGLGEATSV 17704
Score = 37.4 bits (85), Expect = 0.055
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGI------GPFSKISEFKTCIPGFPGAPSAVRISKNVEG 692
K L+PG Y FRV A+N GI GP + + +K PG P P I+K +
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITK--DS 18612
Query: 693 IHLSWEPPTSPSGNILE 709
+ ++W P G +E
Sbjct: 18613 MVVTWARPVDDGGTEIE 18629
Score = 37.4 bits (85), Expect = 0.055
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 20/141 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVEGIHLSWE 698
++L G Y FRV A N GIG P K P PG + V +++N I WE
Sbjct: 18955 ENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI--KWE 19012
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P S G+ + + Y+ ++Q S+ K S L T+
Sbjct: 19013 KPESDGGS--KITGYV----VEMQTKGSE----------KWSTCTQVKTLEATISGLTAG 19056
Query: 759 PAIVFRISAKNEKGYGPATQV 779
VFR++A NEKG Q+
Sbjct: 19057 EEYVFRVAAVNEKGRSDPRQL 19077
Score = 37.0 bits (84), Expect = 0.072
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 27/140 (19%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISE-------FKTCIPGFPGAPSAVRISKNVEGIHL 695
L G+ Y FRVAA N G +++I + F T PG P A + V ++K + L
Sbjct: 7842 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PGPPYALAVVDVTKR--HVDL 7897
Query: 696 SWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WEPP + G ++ + + +L + G TAG N + D
Sbjct: 7898 KWEPPKNDGGRPIQ---------RYVIEKKERLGTRWVKAG------KTAGPDCNFRVTD 7942
Query: 755 YTSRPAIVFRISAKNEKGYG 774
+ F++ A+NE G G
Sbjct: 7943 VIEGTEVQFQVRAENEAGVG 7962
Score = 36.6 bits (83), Expect = 0.094
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQD---LVPGTGYRFRVAAINGCGIGPFSK----I 667
Y++ K S K +V + ++ K+ L+P Y FRV A+N GI K +
Sbjct: 9227 YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9286
Query: 668 SEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
+ +PG PG P + +K + +SW PP G+
Sbjct: 9287 IQDPYRLPGPPGKPKVLARTKG--SMLVSWTPPLDNGGS 9323
Score = 36.6 bits (83), Expect = 0.094
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLSW 697
LVP Y+FR+ A N G+ S SE C P PG + ISK + + L W
Sbjct: 24089 LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK--DSVTLQW 24146
Query: 698 EPPTSPSG-NILEY 710
E P G IL Y
Sbjct: 24147 EKPECDGGKEILGY 24160
Score = 36.2 bits (82), Expect = 0.12
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IP-GFPGAPSAVRISKNVEGIHLSWEPP 700
LV G Y FR+ A+N G P SK +E+ T +P PG P + ++K+ + L W P
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST--VSLIWARP 12908
Query: 701 TSPSGN 706
G+
Sbjct: 12909 KHDGGS 12914
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 646 GTGYRFRVAAINGCGIG-------PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSW 697
G Y FRV+A N G G P S++ PG P V I+ N G+ L+W
Sbjct: 6852 GVEYLFRVSARNRVGTGEPVETDNPVEARSKYDV-----PGPPLNVTITDVNRFGVSLTW 6906
Query: 698 EPPTSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
EPP G I Y L +T+ D T+ V A L+ D
Sbjct: 6907 EPPEYDGGAEITNYVIELRDKTSIRWD---------------TAMTVRAEDLSATVTDVV 6951
Query: 757 SRPAIVFRISAKNEKGYG 774
FR+ A+N G G
Sbjct: 6952 EGQEYSFRVRAQNRIGVG 6969
Score = 35.8 bits (81), Expect = 0.16
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISK-NVEGIHLSWEPP 700
L+PG Y FRV A N GI + P G P P R++K N + I ++W+ P
Sbjct: 12751 LIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP 12810
Query: 701 TSPSGN 706
S G+
Sbjct: 12811 DSDGGS 12816
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L G Y FRV AIN G+G S SE + PG P + I++N + L
Sbjct: 13931 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRN--SVTLI 13988
Query: 697 WEPPTSPSGNIL 708
W P G+ L
Sbjct: 13989 WTEPKYDGGHKL 14000
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTC----IPGFPGAPSAVRISKNVEG 692
L+ L G Y FRVAA N G+G S+ S F + C PG P P S++
Sbjct: 18656 LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS--S 18713
Query: 693 IHLSWEPPTSPSG 705
+ L+W P G
Sbjct: 18714 VSLAWSKPIYDGG 18726
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLS 696
+L GY FRV+A N GI ++S PG PG P+ ++K + ++
Sbjct: 24482 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTK--DSCVVA 24539
Query: 697 WEPPTSPSG 705
W+PP S G
Sbjct: 24540 WKPPASDGG 24548
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISE-FKTCIPG-FPGAPSAVR-ISKNVEGIHLSWE 698
DLV G Y F+V A N CG G + + E P P P V+ + I L+W+
Sbjct: 7245 DLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWD 7304
Query: 699 PPTSPSGN 706
PP + G+
Sbjct: 7305 PPKNDGGS 7312
Score = 35.4 bits (80), Expect = 0.21
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L G Y FRV A N G+GP +++ K P PG P I++N +
Sbjct: 11358 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11417
Query: 694 HLSWEPPTSPSGN 706
SW P S G+
Sbjct: 11418 --SWTLPKSDGGS 11428
Score = 35.4 bits (80), Expect = 0.21
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L+ G Y FR+ A+N G+G P +++ +P P AP ++K + +
Sbjct: 16392 KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTK--DSMI 16449
Query: 695 LSWEPPTSPSGN-ILEY 710
+ WE P S G+ IL Y
Sbjct: 16450 VVWERPASDGGSEILGY 16466
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 18/132 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
DL T + FRV A N GIG P K P +++ S I LSW P
Sbjct: 21123 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSWTKP 21181
Query: 701 TSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPA 760
G+++ + Y+ R + + S + G+ +C + QL +
Sbjct: 21182 DFDGGSVI--TEYVVERKGKGEQTWS-------HAGISKTCEIEVSQLKEQSV------- 21225
Query: 761 IVFRISAKNEKG 772
+ FR+ AKNEKG
Sbjct: 21226 LEFRVFAKNEKG 21237
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGP-FSKISEFKTCIPGFPGAPSAVR----ISKNVEGIHLS 696
DL+ Y FRV A N GIGP I P +P P I+KN +HLS
Sbjct: 9669 DLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT--VHLS 9726
Query: 697 WEPPTSPSGN 706
W+PP + G+
Sbjct: 9727 WKPPKNDGGS 9736
Score = 34.7 bits (78), Expect = 0.36
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 34/243 (13%)
Query: 502 LDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVV-KDETSLTTFSTKSEVDETY 560
LDV +S+ + T+ ++ S ++ K ETS ++ SE ++
Sbjct: 14165 LDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSC 14224
Query: 561 ALPATKISRVETH----ATATPFSKETP--SNPVATVKA----GERQWCDVGIFKNNTAL 610
ATK+ + + + + K P S PV V G + +V NTA
Sbjct: 14225 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTAT 14284
Query: 611 VSQ-------------FYLLPKGKQSISKVGNADVPDYSL-LKKQDLVPGTGYRFRVAAI 656
VS +++ + K+S+ V P L K L G+ Y FRV+A
Sbjct: 14285 VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14344
Query: 657 NGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYS 711
N GIGP S+ S+ PG P P +K + L+W P G LE +
Sbjct: 14345 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTK--KSASLAWGKPHYDGG--LEIT 14400
Query: 712 AYL 714
Y+
Sbjct: 14401 GYV 14403
Score = 34.3 bits (77), Expect = 0.46
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 24/138 (17%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLS 696
K ++L G Y FRV A N G+G P + K P P P V ++ + L
Sbjct: 17870 KVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--PSPPGKVTLTDVSQTSASLM 17927
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WE P G+ +L Y + + G + IV ++ NA +
Sbjct: 17928 WEKPEHDGGSRVLGYVVEMQPK------------------GTEKWSIVAESKVCNAVVTG 17969
Query: 755 YTSRPAIVFRISAKNEKG 772
+S FR+ A NEKG
Sbjct: 17970 LSSGQEYQFRVKAYNEKG 17987
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 24/180 (13%)
Query: 611 VSQFYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PF 664
++ ++L K K S V + +P+ + K Q+L+P Y+FRV A N GIG P
Sbjct: 12122 ITGYFLEKKEKHSTRWVPVNKSAIPERRM-KVQNLLPDHEYQFRVKAENEIGIGEPSLPS 12180
Query: 665 SKISEFKTCIPGFPGAPSAVRISKNVE-GIHLSWEPPTSPSGNILEYSAYLAIRTAQIQD 723
+ P PG P+ R+ + I L W P G Y+ +I D
Sbjct: 12181 RPVVAKDPIEP--PGPPTNFRVVDTTKHSITLGWGKPVYDGG--APIIGYVVEMRPKIAD 12236
Query: 724 NPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTS---RPAIVFRISAKNEKGYGPATQVR 780
+ R C A QL TS FR+ A+N+ G G +++
Sbjct: 12237 ASPDEGWKR--CN-------AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK 12287
Score = 33.9 bits (76), Expect = 0.61
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 22/137 (16%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTC-IPGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG P K +P PG + +++N + LS
Sbjct: 16788 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRN--SVSLS 16845
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P G+ I++Y +V M+ K S L +
Sbjct: 16846 WTKPEHDGGSKIIQY-----------------IVEMQAKHSEKWSECARVKSLQAVITNL 16888
Query: 756 TSRPAIVFRISAKNEKG 772
T +FR+ A NEKG
Sbjct: 16889 TQGEEYLFRVVAVNEKG 16905
Score = 33.5 bits (75), Expect = 0.79
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISKNVEG-IHLSWEPP 700
L+ G Y+FRV A N G GP +I P G P +P + ++ + I L W+ P
Sbjct: 8954 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 9013
Query: 701 TSPSGNILE 709
S G+ ++
Sbjct: 9014 RSNGGSPIQ 9022
Score = 33.5 bits (75), Expect = 0.79
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 651 FRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-EGIHLSWEPPTSPSGNILE 709
+ + A N G SK + K + PG P++V+I+K + LSWEPP G+ E
Sbjct: 13061 YTITAENSSG----SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS--E 13114
Query: 710 YSAYLAIRTAQIQDNPSQL-VFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAK 768
+ Y+ + + N +Q+ + I TSC V +L H +Y FRI A+
Sbjct: 13115 ITNYIVDKRETSRPNWAQVSATVPI-----TSCSVE--KLIEGH-EYQ------FRICAE 13160
Query: 769 NEKGYG 774
N+ G G
Sbjct: 13161 NKYGVG 13166
Score = 33.5 bits (75), Expect = 0.79
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRI-SKNVEGIHLS 696
K L+ G Y FRV +N G+G + K P P P+++ I S E + L
Sbjct: 19638 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLC 19697
Query: 697 WEPPTSPSGNILEYSAYLAIR 717
W P S G+ E S Y+ R
Sbjct: 19698 WSRPESDGGS--EISGYIIER 19716
Score = 33.1 bits (74), Expect = 1.0
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEG 692
LK L GT Y FRV AIN G G S S+ PG P P +++
Sbjct: 13242 LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRS--S 13299
Query: 693 IHLSWEPPTSPSGN 706
+ LSW P G+
Sbjct: 13300 VSLSWGKPAYDGGS 13313
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI--PGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG ++ +E P PG + + +++N + LS
Sbjct: 15706 KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRN--SVSLS 15763
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
WE P G+ Y+ + D + +++ T +T G +
Sbjct: 15764 WEKPEHDGGS--RILGYIVEMQTKGSDKWATCATVKV-----TEATIT-GLIQGEEYS-- 15813
Query: 757 SRPAIVFRISAKNEKGYGPATQV 779
FR+SA+NEKG Q+
Sbjct: 15814 ------FRVSAQNEKGISDPRQL 15830
Score = 33.1 bits (74), Expect = 1.0
Identities = 65/270 (24%), Positives = 98/270 (36%), Gaps = 46/270 (17%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDE---TYALPATKI 567
T VS+TV+ T V + T E +K E F +D T LP T
Sbjct: 20313 TEVSATVARTMMKVMKLTTGEEYQFR----IKAENR---FGISDHIDSACVTVKLPYT-- 20363
Query: 568 SRVETHATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSIS-K 626
TP TP T ++ W + N + V ++L K + SI +
Sbjct: 20364 ---------TPGPPSTPWVTNVTRESITVGWHEP--VSNGGSAVVGYHLEMKDRNSILWQ 20412
Query: 627 VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PFSKISEFKTCIPGFPGAPS 682
N V + K + G Y FRV A N G+G P + C P P
Sbjct: 20413 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP--PRNVR 20470
Query: 683 AVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCI 742
ISKN + LSW+ P G+ + + Y+ R +D P + + +
Sbjct: 20471 ITDISKN--SVSLSWQQPAFDGGS--KITGYIVER----RDLPDGRWTKASFTNVTETQF 20522
Query: 743 VTAGQLANAHIDYTSRPAIVFRISAKNEKG 772
+ +G N+ + FR+ A+N G
Sbjct: 20523 IISGLTQNSQYE--------FRVFARNAVG 20544
Score = 33.1 bits (74), Expect = 1.0
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572
V+S+V TQ VT T E S F SE + P +
Sbjct: 22486 VNSSVKRTQIKVTHLTKYMEYS---------------FRVSSENRFGVSKPLESAPIIAE 22530
Query: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADV 632
H P + P + A +W + + + + + +++ K + +I V V
Sbjct: 22531 HPFVPPSAPTRPEVYHVSANAMSIRWEEP--YHDGGSKIIGYWVEKKERNTILWVKENKV 22588
Query: 633 PDYSL-LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPG-----FPGAPSAVRI 686
P K LV G Y+FR A+N G+ SK SE I PG P +
Sbjct: 22589 PCLECNYKVTGLVEGLEYQFRTYALNAAGV---SKASEASRPIMAQNPVDAPGRPEVTDV 22645
Query: 687 SKNVEGIHLSWEPPTSPSGN 706
+++ + L W P G+
Sbjct: 22646 TRST--VSLIWSAPAYDGGS 22663
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/54 (29%), Positives = 27/54 (50%)
Query: 616 LLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE 669
+ P G + +V + + D ++ +VP Y RV A+N G+ S+ISE
Sbjct: 8018 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 8071
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 26/144 (18%)
Query: 643 LVPGTGYRFRVAAINGCGIG-PFSKISEFKT---CIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FR+ A N GIG P E +PG P P+ +++N + ++WE
Sbjct: 9976 LLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRN--SMTVNWE 10033
Query: 699 PPT----SP-SGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
P SP +G LE + R ++ +P + M + K + ++
Sbjct: 10034 EPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDP--IKAMTLGVSYKVTGLIEGS------- 10084
Query: 754 DYTSRPAIVFRISAKNEKGYGPAT 777
DY FR+ A N G GPA+
Sbjct: 10085 DYQ------FRVYAINAAGVGPAS 10102
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 18/139 (12%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGI 693
+L + LV GT Y FRV N GIG + S+ + +P P V ++K+ +
Sbjct: 23289 TLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST--V 23346
Query: 694 HLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
L+WE P G+ L A + + +M++ LK + + N
Sbjct: 23347 TLAWEKPLYDGGSRLTGYVLEACKAGTER-------WMKVVT-LKPTVLEHTVTSLNEGE 23398
Query: 754 DYTSRPAIVFRISAKNEKG 772
Y +FRI A+NEKG
Sbjct: 23399 QY------LFRIRAQNEKG 23411
Score = 31.6 bits (70), Expect = 3.0
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF-----PGAPSAVRIS-KNVE 691
L K +L+ Y FRV A N G+GP E KT I PG P + I+ K
Sbjct: 11754 LIKANLLANNEYYFRVCAENKVGVGP---TIETKTPILAINPIDRPGEPENLHIADKGKT 11810
Query: 692 GIHLSWEPPTSPSGN 706
++L W P G+
Sbjct: 11811 FVYLKWRRPDYDGGS 11825
Score = 31.6 bits (70), Expect = 3.0
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
Query: 614 FYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE-- 669
++L K + SI SK + D + +K L G Y +RV A N GIG SK E
Sbjct: 19316 YHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19374
Query: 670 --FKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
C P PG P I++ + + L W P G
Sbjct: 19375 PARDPCDP--PGQPEVTNITR--KSVSLKWSKPHYDGG 19408
Score = 30.8 bits (68), Expect = 5.1
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHL 695
+DL+P Y FRV A+N G G + ++ I P P + V E + +
Sbjct: 8236 KDLIPNGEYFFRVKAVNKVGGGEYIELK--NPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8293
Query: 696 SWEPPTSPSGN 706
+W+PP G+
Sbjct: 8294 TWKPPLYDGGS 8304
Score = 30.8 bits (68), Expect = 5.1
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 20/139 (14%)
Query: 637 LLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGIH 694
+ K DL G Y FRV+A+N G+G ++ E T P P V SK+
Sbjct: 22201 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKS--SAV 22258
Query: 695 LSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHID 754
L+W P G+ + YL + D + G T +L
Sbjct: 22259 LAWLKPDHDGGS--RITGYLLEMRQKGSD-------FWVEAGHTKQLTFTVERL------ 22303
Query: 755 YTSRPAIVFRISAKNEKGY 773
+ FR+ AKN+ GY
Sbjct: 22304 -VEKTEYEFRVKAKNDAGY 22321
Score = 30.4 bits (67), Expect = 6.7
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-----PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
+LVPG Y FRV A+N G G P ++ P P ++KN L+
Sbjct: 12456 NLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN--SATLA 12513
Query: 697 WEPPTSPSG 705
W PP G
Sbjct: 12514 WLPPLRDGG 12522
Score = 30.4 bits (67), Expect = 6.7
Identities = 39/151 (25%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
+L G Y FRV A N GIG P K P VR S + + W+ P
Sbjct: 13544 NLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVR-SVSKSSCSIGWKKP 13602
Query: 701 TSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S G+ I+ Y + ++N Q V + L + D T
Sbjct: 13603 HSDGGSRIIGY-----VVDFLTEENKWQRVMKSL-------------SLQYSAKDLTEGK 13644
Query: 760 AIVFRISAKNEKGYGPATQVRWLQGNNKKAP 790
FR+SA+NE G G +++ + ++ AP
Sbjct: 13645 EYTFRVSAENENGEGTPSEITVVARDDVVAP 13675
Score = 30.4 bits (67), Expect = 6.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L+ G Y FR+ A+N G+G P + + +PG P + I+K + +
Sbjct: 17473 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK--DSM 17530
Query: 694 HLSWEPPTSPSGN 706
+ W P S G+
Sbjct: 17531 TVCWNRPDSDGGS 17543
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 50.1 bits (118), Expect = 8e-06
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 44/208 (21%)
Query: 533 SSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETH-------ATATPFSKET-- 583
SS N V K +TS TT+ V T A K R++T A + K T
Sbjct: 15899 SSINNYIVEKRDTSTTTWQI---VSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYL 15955
Query: 584 ----------------PSNPVATVKAG---ERQWCDVGIFKNNTALVSQFYLLPKGKQSI 624
P PV T+ + E QW + + + V ++L K + SI
Sbjct: 15956 NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP--ISDGGSRVIGYHLERKERNSI 16013
Query: 625 S--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFP 678
K+ +P + K L G Y FRV+A N GIG SK+SE C P P
Sbjct: 16014 LWVKLNKTPIPQ-TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP--P 16070
Query: 679 GAPSAVRISKNVEGIHLSWEPPTSPSGN 706
G P A+ +++N + L W+ PT G+
Sbjct: 16071 GRPEAIIVTRN--SVTLQWKKPTYDGGS 16096
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/199 (28%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 536 TNGAVVKDETSLTTFSTKSEVDETYALPATKISR----------VETHATATPFSKETPS 585
T+ V K ETS +S SE E + TKI + V + P ++
Sbjct: 20627 THYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 20686
Query: 586 NPVATVKAGERQWCDVG-IFKNNTALV------------SQFYLLPKGKQSIS--KVGNA 630
A V G +V I KN+ +V S ++L + K+S+ KV
Sbjct: 20687 AKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKE 20746
Query: 631 DVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISK 688
+ D + K L + Y++RV A+N G GPFS+ SEF K P PG P+ +RI+
Sbjct: 20747 TIRD-TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20805
Query: 689 NVE-GIHLSWEPPTSPSGN 706
+ + I L W P G+
Sbjct: 20806 STKSSITLGWSKPVYDGGS 20824
Score = 43.9 bits (102), Expect = 6e-04
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 30/207 (14%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRV 570
T+V VS+T T + K ++ + E F+ ++ +++AL + I
Sbjct: 16995 TTVWDVVSATVARTTLKVTKLKTGT--------EYQFRIFA-ENRYGQSFALESDPIVAQ 17045
Query: 571 ETHATATPFSKETPSNPVATVKAGER---QWCDVGIFKNNTALVSQFYLLPKGKQSI--S 625
+ P P P AT + + QW + N + V ++L K + SI +
Sbjct: 17046 YPYKEPGP-----PGTPFATAISKDSMVIQWHEP--VNNGGSPVIGYHLERKERNSILWT 17098
Query: 626 KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFPGAP 681
KV + D + K Q+L G Y FRV A N G+G SK SE C P PG P
Sbjct: 17099 KVNKTIIHD-TQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP--PGTP 17155
Query: 682 SAVRISKNVEGIHLSWEPPTSPSGNIL 708
+ + +N I L W P G+++
Sbjct: 17156 EPIMVKRN--EITLQWTKPVYDGGSMI 17180
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGF-PGAPSAVRI-SKNVEGIHLSWEP 699
L+ G Y+FR AIN GIGP S+ S+ + P F PG PS + K I L W+P
Sbjct: 9296 LLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKP 9355
Query: 700 PTSPSGN 706
P G+
Sbjct: 9356 PAKDGGS 9362
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 611 VSQFYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKIS 668
+S + + + K+S+ ++V V + LK L+ G Y+FRV A+N G S+ S
Sbjct: 22899 ISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22958
Query: 669 EFKTC-----IPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
F +C PG P AP V +K+ I L+W P G
Sbjct: 22959 NFISCREPSYTPGPPSAPRVVDTTKH--SISLAWTKPMYDGG 22998
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 38/215 (17%)
Query: 581 KETPSNPVATVK----AGERQ--WCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPD 634
++TP V ++ GE+ W D + N+ Y++ K + S++ A + D
Sbjct: 21677 QDTPGKVVGPIRFTNITGEKMTLWWDAPL--NDGCAPITHYIIEK--RETSRLAWALIED 21732
Query: 635 ------YSLLKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAV 684
Y+ +K L+ G Y+FRV+A+N G+G P +++ + +P PG P
Sbjct: 21733 KCEAQSYTAIK---LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPS 21789
Query: 685 RISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVT 744
I+ N I L+W P S G+ E Y+ R + +++ R +T VT
Sbjct: 21790 NITGN--SITLTWARPESDGGS--EIQQYILERREKKSTRWVKVISKRPIS--ETRFKVT 21843
Query: 745 AGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQV 779
N + F + A+N G GPA+ +
Sbjct: 21844 GLTEGNEY---------EFHVMAENAAGVGPASGI 21869
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 23/200 (11%)
Query: 530 KTESSSTNGAVVKDETSLTTFSTKSEVDET-----------YALPATKISR--VETHATA 576
K E+S TN +V + TTF + V + Y + +S V H
Sbjct: 21324 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21383
Query: 577 TPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSI--SKVGNADVPD 634
P P T W D ++ + V+ F++ K + SI KV + +
Sbjct: 21384 IPGPPGKPVIYNVTSDGMSLTW-DAPVYDGGSE-VTGFHVEKKERNSILWQKVNTSPISG 21441
Query: 635 YSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEG 692
+ LV G Y+FRV A N G+ S S+F + PG P + +++ E
Sbjct: 21442 REY-RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTR--ET 21498
Query: 693 IHLSWEPPTSPSGN-ILEYS 711
I L W PP G+ I+ YS
Sbjct: 21499 ITLKWNPPLRDGGSKIVGYS 21518
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 614 FYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF- 670
++L K K SI K+ + D + K L G Y F+V+A N GIG SK+SE
Sbjct: 18167 YHLEQKEKNSILWVKLNKTPIQD-TKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 18225
Query: 671 ---KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
C P PG P A+ I++N + L W+ P G+
Sbjct: 18226 VARDPCDP--PGRPEAIVITRN--NVTLKWKKPAYDGGS 18260
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHL 695
Q L+ G Y FR+AA N G+GPF + SE +P P ++KN + L
Sbjct: 10306 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNT--VTL 10363
Query: 696 SWEPPTSPSGN-ILEY 710
+W PP G+ I+ Y
Sbjct: 10364 TWNPPKYDGGSEIINY 10379
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L G Y+FRV A N G+GP ++ + +PG PG P ++K + +
Sbjct: 14847 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTK--DSMT 14904
Query: 695 LSWEPPTSPSGN-ILEY 710
+SW P S G+ IL Y
Sbjct: 14905 ISWHEPLSDGGSPILGY 14921
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L+ G+ Y+FRV AIN G+GP S S+ T PG P L
Sbjct: 10009 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLE 10068
Query: 697 WEPPTSPSGN-----ILEY 710
W PP G+ I+EY
Sbjct: 10069 WSPPLKDGGSKVTGYIVEY 10087
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPF--SKISEFKTCIPGFPGAPSAVRI-SKNVEG 692
S K L G Y FRVAA N GIG + S++ E ++ I PG P ++I + +G
Sbjct: 23517 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI-RIPGPPETLQIFDVSRDG 23575
Query: 693 IHLSWEPPTSPSGN 706
+ L+W PP G+
Sbjct: 23576 MTLTWYPPEDDGGS 23589
Score = 39.7 bits (91), Expect = 0.011
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 615 YLLPKGKQSISK----VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG---PFSKI 667
Y+L K ++++SK V + Y+ + DL+ G Y FRV+A N GIG P SK
Sbjct: 10673 YILEK-RETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10731
Query: 668 SEFKTCI--PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN-ILEY 710
K I P P P A+ + N + L+W+PP G+ IL Y
Sbjct: 10732 VFAKDPIAKPSPPVNPEAIDTTCN--SVDLTWQPPRHDGGSKILGY 10775
Score = 38.5 bits (88), Expect = 0.025
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 34/147 (23%)
Query: 643 LVPGTGYRFRVAAINGCGIG------PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
L+ G Y FRV+A+N G G P + F PG P P ++KN + S
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGP--PGPPEKPEVSNVTKNTATV--S 14219
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTS-----CIVTAGQLANA 751
W+ P G+ E + Y R + +R +KT C VT Q +
Sbjct: 14220 WKRPVDDGGS--EITGYHVERREKKS--------LRWVRAIKTPVSDLRCKVTGLQEGST 14269
Query: 752 HIDYTSRPAIVFRISAKNEKGYGPATQ 778
+ FR+SA+N G GP ++
Sbjct: 14270 Y---------EFRVSAENRAGIGPPSE 14287
Score = 37.7 bits (86), Expect = 0.042
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 25/145 (17%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISKNVE-GIHLSWE 698
D+V G Y FRV A N G+G S + F K P P P + S + + L WE
Sbjct: 6882 DVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWE 6941
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLK----TSCIVTAGQLANAHID 754
PP G+ + Y+ R + +DN I C +K + VT + N ++
Sbjct: 6942 PPLKDGGSPI--LGYIIERCEEGKDN-------WIRCNMKLVPELTYKVTGLEKGNKYL- 6991
Query: 755 YTSRPAIVFRISAKNEKGYGPATQV 779
+R+SA+N+ G +++
Sbjct: 6992 --------YRVSAENKAGVSDPSEI 7008
Score = 37.7 bits (86), Expect = 0.042
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGFPGAPSAVRIS-KNVEGIHLSWEPP 700
L+ G Y FRV A N G G FS S+ KT P P P R++ + I L WEPP
Sbjct: 8594 LLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPP 8653
Query: 701 T-SPSGNILEY 710
+ G I+ Y
Sbjct: 8654 AFNGGGEIVGY 8664
Score = 37.7 bits (86), Expect = 0.042
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVE-GIHL 695
K L G Y F V A N G+GP S IS C PG P+ V+++ + + L
Sbjct: 21841 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSL 21900
Query: 696 SWEPPTSPSG 705
W P G
Sbjct: 21901 EWSKPVFDGG 21910
Score = 37.4 bits (85), Expect = 0.055
Identities = 50/230 (21%), Positives = 97/230 (42%), Gaps = 26/230 (11%)
Query: 495 VGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKS 554
+ + + D++ +PE S + T +V ++ ++ + T VKD T T+
Sbjct: 7721 INITKNTADLKWTVPEKDGGSPI--TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7778
Query: 555 E-----VDETYALPATKISRVETHATATP-FSKETPSNPVATVKAGER----QWCDVGIF 604
V A+ + + +E A F+ P +A V +R +W
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP--- 7835
Query: 605 KNNTALVSQFYLLPKGKQSIS---KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGI 661
KN+ Q Y++ K ++ + K G PD + + D++ GT +F+V A N G+
Sbjct: 7836 KNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF-RVTDVIEGTEVQFQVRAENEAGV 7894
Query: 662 GPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHLSWEPPTSPSGN 706
G S+ +E + P +P + + +V + I ++W+PP G+
Sbjct: 7895 GHPSEPTEILSIED--PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 7942
Score = 37.4 bits (85), Expect = 0.055
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSK----ISEFKTCIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FRV A N G GP ++ I++ K PG P P ++SK E + + W
Sbjct: 11988 LIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK--EEMTVVWN 12045
Query: 699 PPTSPSG 705
PP G
Sbjct: 12046 PPEYDGG 12052
Score = 37.4 bits (85), Expect = 0.055
Identities = 39/135 (28%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 649 YRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVE-GIHLSWEPPTSPSG 705
Y FRV+A N G+G P +K C P F PG P+ I + I L+W P G
Sbjct: 17517 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17576
Query: 706 N-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFR 764
+ IL Y + + + Q+V +T VT +++ T R
Sbjct: 17577 SEILGY----VVEICKADEEEWQIVTP------QTGLRVTRFEISK----LTEHQEYKIR 17622
Query: 765 ISAKNEKGYGPATQV 779
+ A N+ G G AT V
Sbjct: 17623 VCALNKVGLGEATSV 17637
Score = 37.4 bits (85), Expect = 0.055
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGI------GPFSKISEFKTCIPGFPGAPSAVRISKNVEG 692
K L+PG Y FRV A+N GI GP + + +K PG P P I+K +
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITK--DS 18545
Query: 693 IHLSWEPPTSPSGNILE 709
+ ++W P G +E
Sbjct: 18546 MVVTWARPVDDGGTEIE 18562
Score = 37.4 bits (85), Expect = 0.055
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 20/141 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVEGIHLSWE 698
++L G Y FRV A N GIG P K P PG + V +++N I WE
Sbjct: 18888 ENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI--KWE 18945
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P S G+ + + Y+ ++Q S+ K S L T+
Sbjct: 18946 KPESDGGS--KITGYV----VEMQTKGSE----------KWSTCTQVKTLEATISGLTAG 18989
Query: 759 PAIVFRISAKNEKGYGPATQV 779
VFR++A NEKG Q+
Sbjct: 18990 EEYVFRVAAVNEKGRSDPRQL 19010
Score = 37.0 bits (84), Expect = 0.072
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 27/140 (19%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISE-------FKTCIPGFPGAPSAVRISKNVEGIHL 695
L G+ Y FRVAA N G +++I + F T PG P A + V ++K + L
Sbjct: 7775 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PGPPYALAVVDVTKR--HVDL 7830
Query: 696 SWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WEPP + G ++ + + +L + G TAG N + D
Sbjct: 7831 KWEPPKNDGGRPIQ---------RYVIEKKERLGTRWVKAG------KTAGPDCNFRVTD 7875
Query: 755 YTSRPAIVFRISAKNEKGYG 774
+ F++ A+NE G G
Sbjct: 7876 VIEGTEVQFQVRAENEAGVG 7895
Score = 36.6 bits (83), Expect = 0.094
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQD---LVPGTGYRFRVAAINGCGIGPFSK----I 667
Y++ K S K +V + ++ K+ L+P Y FRV A+N GI K +
Sbjct: 9160 YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9219
Query: 668 SEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
+ +PG PG P + +K + +SW PP G+
Sbjct: 9220 IQDPYRLPGPPGKPKVLARTKG--SMLVSWTPPLDNGGS 9256
Score = 36.6 bits (83), Expect = 0.094
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLSW 697
LVP Y+FR+ A N G+ S SE C P PG + ISK + + L W
Sbjct: 24022 LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK--DSVTLQW 24079
Query: 698 EPPTSPSG-NILEY 710
E P G IL Y
Sbjct: 24080 EKPECDGGKEILGY 24093
Score = 36.2 bits (82), Expect = 0.12
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IP-GFPGAPSAVRISKNVEGIHLSWEPP 700
LV G Y FR+ A+N G P SK +E+ T +P PG P + ++K+ + L W P
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST--VSLIWARP 12841
Query: 701 TSPSGN 706
G+
Sbjct: 12842 KHDGGS 12847
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 646 GTGYRFRVAAINGCGIG-------PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSW 697
G Y FRV+A N G G P S++ PG P V I+ N G+ L+W
Sbjct: 6785 GVEYLFRVSARNRVGTGEPVETDNPVEARSKYDV-----PGPPLNVTITDVNRFGVSLTW 6839
Query: 698 EPPTSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
EPP G I Y L +T+ D T+ V A L+ D
Sbjct: 6840 EPPEYDGGAEITNYVIELRDKTSIRWD---------------TAMTVRAEDLSATVTDVV 6884
Query: 757 SRPAIVFRISAKNEKGYG 774
FR+ A+N G G
Sbjct: 6885 EGQEYSFRVRAQNRIGVG 6902
Score = 35.8 bits (81), Expect = 0.16
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISK-NVEGIHLSWEPP 700
L+PG Y FRV A N GI + P G P P R++K N + I ++W+ P
Sbjct: 12684 LIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP 12743
Query: 701 TSPSGN 706
S G+
Sbjct: 12744 DSDGGS 12749
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L G Y FRV AIN G+G S SE + PG P + I++N + L
Sbjct: 13864 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRN--SVTLI 13921
Query: 697 WEPPTSPSGNIL 708
W P G+ L
Sbjct: 13922 WTEPKYDGGHKL 13933
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTC----IPGFPGAPSAVRISKNVEG 692
L+ L G Y FRVAA N G+G S+ S F + C PG P P S++
Sbjct: 18589 LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS--S 18646
Query: 693 IHLSWEPPTSPSG 705
+ L+W P G
Sbjct: 18647 VSLAWSKPIYDGG 18659
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLS 696
+L GY FRV+A N GI ++S PG PG P+ ++K + ++
Sbjct: 24415 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTK--DSCVVA 24472
Query: 697 WEPPTSPSG 705
W+PP S G
Sbjct: 24473 WKPPASDGG 24481
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISE-FKTCIPG-FPGAPSAVR-ISKNVEGIHLSWE 698
DLV G Y F+V A N CG G + + E P P P V+ + I L+W+
Sbjct: 7178 DLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWD 7237
Query: 699 PPTSPSGN 706
PP + G+
Sbjct: 7238 PPKNDGGS 7245
Score = 35.4 bits (80), Expect = 0.21
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L G Y FRV A N G+GP +++ K P PG P I++N +
Sbjct: 11291 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11350
Query: 694 HLSWEPPTSPSGN 706
SW P S G+
Sbjct: 11351 --SWTLPKSDGGS 11361
Score = 35.4 bits (80), Expect = 0.21
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L+ G Y FR+ A+N G+G P +++ +P P AP ++K + +
Sbjct: 16325 KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTK--DSMI 16382
Query: 695 LSWEPPTSPSGN-ILEY 710
+ WE P S G+ IL Y
Sbjct: 16383 VVWERPASDGGSEILGY 16399
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 18/132 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
DL T + FRV A N GIG P K P +++ S I LSW P
Sbjct: 21056 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSWTKP 21114
Query: 701 TSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPA 760
G+++ + Y+ R + + S + G+ +C + QL +
Sbjct: 21115 DFDGGSVI--TEYVVERKGKGEQTWS-------HAGISKTCEIEVSQLKEQSV------- 21158
Query: 761 IVFRISAKNEKG 772
+ FR+ AKNEKG
Sbjct: 21159 LEFRVFAKNEKG 21170
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGP-FSKISEFKTCIPGFPGAPSAVR----ISKNVEGIHLS 696
DL+ Y FRV A N GIGP I P +P P I+KN +HLS
Sbjct: 9602 DLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT--VHLS 9659
Query: 697 WEPPTSPSGN 706
W+PP + G+
Sbjct: 9660 WKPPKNDGGS 9669
Score = 34.7 bits (78), Expect = 0.36
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 34/243 (13%)
Query: 502 LDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVV-KDETSLTTFSTKSEVDETY 560
LDV +S+ + T+ ++ S ++ K ETS ++ SE ++
Sbjct: 14098 LDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSC 14157
Query: 561 ALPATKISRVETH----ATATPFSKETP--SNPVATVKA----GERQWCDVGIFKNNTAL 610
ATK+ + + + + K P S PV V G + +V NTA
Sbjct: 14158 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTAT 14217
Query: 611 VSQ-------------FYLLPKGKQSISKVGNADVPDYSL-LKKQDLVPGTGYRFRVAAI 656
VS +++ + K+S+ V P L K L G+ Y FRV+A
Sbjct: 14218 VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14277
Query: 657 NGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYS 711
N GIGP S+ S+ PG P P +K + L+W P G LE +
Sbjct: 14278 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTK--KSASLAWGKPHYDGG--LEIT 14333
Query: 712 AYL 714
Y+
Sbjct: 14334 GYV 14336
Score = 34.3 bits (77), Expect = 0.46
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 24/138 (17%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLS 696
K ++L G Y FRV A N G+G P + K P P P V ++ + L
Sbjct: 17803 KVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--PSPPGKVTLTDVSQTSASLM 17860
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WE P G+ +L Y + + G + IV ++ NA +
Sbjct: 17861 WEKPEHDGGSRVLGYVVEMQPK------------------GTEKWSIVAESKVCNAVVTG 17902
Query: 755 YTSRPAIVFRISAKNEKG 772
+S FR+ A NEKG
Sbjct: 17903 LSSGQEYQFRVKAYNEKG 17920
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 24/180 (13%)
Query: 611 VSQFYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PF 664
++ ++L K K S V + +P+ + K Q+L+P Y+FRV A N GIG P
Sbjct: 12055 ITGYFLEKKEKHSTRWVPVNKSAIPERRM-KVQNLLPDHEYQFRVKAENEIGIGEPSLPS 12113
Query: 665 SKISEFKTCIPGFPGAPSAVRISKNVE-GIHLSWEPPTSPSGNILEYSAYLAIRTAQIQD 723
+ P PG P+ R+ + I L W P G Y+ +I D
Sbjct: 12114 RPVVAKDPIEP--PGPPTNFRVVDTTKHSITLGWGKPVYDGG--APIIGYVVEMRPKIAD 12169
Query: 724 NPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTS---RPAIVFRISAKNEKGYGPATQVR 780
+ R C A QL TS FR+ A+N+ G G +++
Sbjct: 12170 ASPDEGWKR--CN-------AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK 12220
Score = 33.9 bits (76), Expect = 0.61
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 22/137 (16%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTC-IPGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG P K +P PG + +++N + LS
Sbjct: 16721 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRN--SVSLS 16778
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P G+ I++Y +V M+ K S L +
Sbjct: 16779 WTKPEHDGGSKIIQY-----------------IVEMQAKHSEKWSECARVKSLQAVITNL 16821
Query: 756 TSRPAIVFRISAKNEKG 772
T +FR+ A NEKG
Sbjct: 16822 TQGEEYLFRVVAVNEKG 16838
Score = 33.5 bits (75), Expect = 0.79
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISKNVEG-IHLSWEPP 700
L+ G Y+FRV A N G GP +I P G P +P + ++ + I L W+ P
Sbjct: 8887 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 8946
Query: 701 TSPSGNILE 709
S G+ ++
Sbjct: 8947 RSNGGSPIQ 8955
Score = 33.5 bits (75), Expect = 0.79
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 651 FRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-EGIHLSWEPPTSPSGNILE 709
+ + A N G SK + K + PG P++V+I+K + LSWEPP G+ E
Sbjct: 12994 YTITAENSSG----SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS--E 13047
Query: 710 YSAYLAIRTAQIQDNPSQL-VFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAK 768
+ Y+ + + N +Q+ + I TSC V +L H +Y FRI A+
Sbjct: 13048 ITNYIVDKRETSRPNWAQVSATVPI-----TSCSVE--KLIEGH-EYQ------FRICAE 13093
Query: 769 NEKGYG 774
N+ G G
Sbjct: 13094 NKYGVG 13099
Score = 33.5 bits (75), Expect = 0.79
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRI-SKNVEGIHLS 696
K L+ G Y FRV +N G+G + K P P P+++ I S E + L
Sbjct: 19571 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLC 19630
Query: 697 WEPPTSPSGNILEYSAYLAIR 717
W P S G+ E S Y+ R
Sbjct: 19631 WSRPESDGGS--EISGYIIER 19649
Score = 33.1 bits (74), Expect = 1.0
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEG 692
LK L GT Y FRV AIN G G S S+ PG P P +++
Sbjct: 13175 LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRS--S 13232
Query: 693 IHLSWEPPTSPSGN 706
+ LSW P G+
Sbjct: 13233 VSLSWGKPAYDGGS 13246
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI--PGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG ++ +E P PG + + +++N + LS
Sbjct: 15639 KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRN--SVSLS 15696
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
WE P G+ Y+ + D + +++ T +T G +
Sbjct: 15697 WEKPEHDGGS--RILGYIVEMQTKGSDKWATCATVKV-----TEATIT-GLIQGEEYS-- 15746
Query: 757 SRPAIVFRISAKNEKGYGPATQV 779
FR+SA+NEKG Q+
Sbjct: 15747 ------FRVSAQNEKGISDPRQL 15763
Score = 33.1 bits (74), Expect = 1.0
Identities = 65/270 (24%), Positives = 98/270 (36%), Gaps = 46/270 (17%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDE---TYALPATKI 567
T VS+TV+ T V + T E +K E F +D T LP T
Sbjct: 20246 TEVSATVARTMMKVMKLTTGEEYQFR----IKAENR---FGISDHIDSACVTVKLPYT-- 20296
Query: 568 SRVETHATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSIS-K 626
TP TP T ++ W + N + V ++L K + SI +
Sbjct: 20297 ---------TPGPPSTPWVTNVTRESITVGWHEP--VSNGGSAVVGYHLEMKDRNSILWQ 20345
Query: 627 VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PFSKISEFKTCIPGFPGAPS 682
N V + K + G Y FRV A N G+G P + C P P
Sbjct: 20346 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP--PRNVR 20403
Query: 683 AVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCI 742
ISKN + LSW+ P G+ + + Y+ R +D P + + +
Sbjct: 20404 ITDISKN--SVSLSWQQPAFDGGS--KITGYIVER----RDLPDGRWTKASFTNVTETQF 20455
Query: 743 VTAGQLANAHIDYTSRPAIVFRISAKNEKG 772
+ +G N+ + FR+ A+N G
Sbjct: 20456 IISGLTQNSQYE--------FRVFARNAVG 20477
Score = 33.1 bits (74), Expect = 1.0
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572
V+S+V TQ VT T E S F SE + P +
Sbjct: 22419 VNSSVKRTQIKVTHLTKYMEYS---------------FRVSSENRFGVSKPLESAPIIAE 22463
Query: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADV 632
H P + P + A +W + + + + + +++ K + +I V V
Sbjct: 22464 HPFVPPSAPTRPEVYHVSANAMSIRWEEP--YHDGGSKIIGYWVEKKERNTILWVKENKV 22521
Query: 633 PDYSL-LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPG-----FPGAPSAVRI 686
P K LV G Y+FR A+N G+ SK SE I PG P +
Sbjct: 22522 PCLECNYKVTGLVEGLEYQFRTYALNAAGV---SKASEASRPIMAQNPVDAPGRPEVTDV 22578
Query: 687 SKNVEGIHLSWEPPTSPSGN 706
+++ + L W P G+
Sbjct: 22579 TRST--VSLIWSAPAYDGGS 22596
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/54 (29%), Positives = 27/54 (50%)
Query: 616 LLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE 669
+ P G + +V + + D ++ +VP Y RV A+N G+ S+ISE
Sbjct: 7951 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 8004
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 26/144 (18%)
Query: 643 LVPGTGYRFRVAAINGCGIG-PFSKISEFKT---CIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FR+ A N GIG P E +PG P P+ +++N + ++WE
Sbjct: 9909 LLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRN--SMTVNWE 9966
Query: 699 PPT----SP-SGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
P SP +G LE + R ++ +P + M + K + ++
Sbjct: 9967 EPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDP--IKAMTLGVSYKVTGLIEGS------- 10017
Query: 754 DYTSRPAIVFRISAKNEKGYGPAT 777
DY FR+ A N G GPA+
Sbjct: 10018 DYQ------FRVYAINAAGVGPAS 10035
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 18/139 (12%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGI 693
+L + LV GT Y FRV N GIG + S+ + +P P V ++K+ +
Sbjct: 23222 TLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST--V 23279
Query: 694 HLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
L+WE P G+ L A + + +M++ LK + + N
Sbjct: 23280 TLAWEKPLYDGGSRLTGYVLEACKAGTER-------WMKVVT-LKPTVLEHTVTSLNEGE 23331
Query: 754 DYTSRPAIVFRISAKNEKG 772
Y +FRI A+NEKG
Sbjct: 23332 QY------LFRIRAQNEKG 23344
Score = 31.6 bits (70), Expect = 3.0
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF-----PGAPSAVRIS-KNVE 691
L K +L+ Y FRV A N G+GP E KT I PG P + I+ K
Sbjct: 11687 LIKANLLANNEYYFRVCAENKVGVGP---TIETKTPILAINPIDRPGEPENLHIADKGKT 11743
Query: 692 GIHLSWEPPTSPSGN 706
++L W P G+
Sbjct: 11744 FVYLKWRRPDYDGGS 11758
Score = 31.6 bits (70), Expect = 3.0
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
Query: 614 FYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE-- 669
++L K + SI SK + D + +K L G Y +RV A N GIG SK E
Sbjct: 19249 YHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19307
Query: 670 --FKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
C P PG P I++ + + L W P G
Sbjct: 19308 PARDPCDP--PGQPEVTNITR--KSVSLKWSKPHYDGG 19341
Score = 30.8 bits (68), Expect = 5.1
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHL 695
+DL+P Y FRV A+N G G + ++ I P P + V E + +
Sbjct: 8169 KDLIPNGEYFFRVKAVNKVGGGEYIELK--NPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8226
Query: 696 SWEPPTSPSGN 706
+W+PP G+
Sbjct: 8227 TWKPPLYDGGS 8237
Score = 30.8 bits (68), Expect = 5.1
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 20/139 (14%)
Query: 637 LLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGIH 694
+ K DL G Y FRV+A+N G+G ++ E T P P V SK+
Sbjct: 22134 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKS--SAV 22191
Query: 695 LSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHID 754
L+W P G+ + YL + D + G T +L
Sbjct: 22192 LAWLKPDHDGGS--RITGYLLEMRQKGSD-------FWVEAGHTKQLTFTVERL------ 22236
Query: 755 YTSRPAIVFRISAKNEKGY 773
+ FR+ AKN+ GY
Sbjct: 22237 -VEKTEYEFRVKAKNDAGY 22254
Score = 30.4 bits (67), Expect = 6.7
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-----PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
+LVPG Y FRV A+N G G P ++ P P ++KN L+
Sbjct: 12389 NLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN--SATLA 12446
Query: 697 WEPPTSPSG 705
W PP G
Sbjct: 12447 WLPPLRDGG 12455
Score = 30.4 bits (67), Expect = 6.7
Identities = 39/151 (25%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
+L G Y FRV A N GIG P K P VR S + + W+ P
Sbjct: 13477 NLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVR-SVSKSSCSIGWKKP 13535
Query: 701 TSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S G+ I+ Y + ++N Q V + L + D T
Sbjct: 13536 HSDGGSRIIGY-----VVDFLTEENKWQRVMKSL-------------SLQYSAKDLTEGK 13577
Query: 760 AIVFRISAKNEKGYGPATQVRWLQGNNKKAP 790
FR+SA+NE G G +++ + ++ AP
Sbjct: 13578 EYTFRVSAENENGEGTPSEITVVARDDVVAP 13608
Score = 30.4 bits (67), Expect = 6.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L+ G Y FR+ A+N G+G P + + +PG P + I+K + +
Sbjct: 17406 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK--DSM 17463
Query: 694 HLSWEPPTSPSGN 706
+ W P S G+
Sbjct: 17464 TVCWNRPDSDGGS 17476
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 50.1 bits (118), Expect = 8e-06
Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 44/208 (21%)
Query: 533 SSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETH-------ATATPFSKET-- 583
SS N V K +TS TT+ V T A K R++T A + K T
Sbjct: 15774 SSINNYIVEKRDTSTTTWQI---VSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYL 15830
Query: 584 ----------------PSNPVATVKAG---ERQWCDVGIFKNNTALVSQFYLLPKGKQSI 624
P PV T+ + E QW + + + V ++L K + SI
Sbjct: 15831 NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP--ISDGGSRVIGYHLERKERNSI 15888
Query: 625 S--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFP 678
K+ +P + K L G Y FRV+A N GIG SK+SE C P P
Sbjct: 15889 LWVKLNKTPIPQ-TKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCDP--P 15945
Query: 679 GAPSAVRISKNVEGIHLSWEPPTSPSGN 706
G P A+ +++N + L W+ PT G+
Sbjct: 15946 GRPEAIIVTRN--SVTLQWKKPTYDGGS 15971
Score = 48.5 bits (114), Expect = 2e-05
Identities = 57/199 (28%), Positives = 85/199 (42%), Gaps = 29/199 (14%)
Query: 536 TNGAVVKDETSLTTFSTKSEVDETYALPATKISR----------VETHATATPFSKETPS 585
T+ V K ETS +S SE E + TKI + V + P ++
Sbjct: 20502 THYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVV 20561
Query: 586 NPVATVKAGERQWCDVG-IFKNNTALV------------SQFYLLPKGKQSIS--KVGNA 630
A V G +V I KN+ +V S ++L + K+S+ KV
Sbjct: 20562 AKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKE 20621
Query: 631 DVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISK 688
+ D + K L + Y++RV A+N G GPFS+ SEF K P PG P+ +RI+
Sbjct: 20622 TIRD-TRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIAD 20680
Query: 689 NVE-GIHLSWEPPTSPSGN 706
+ + I L W P G+
Sbjct: 20681 STKSSITLGWSKPVYDGGS 20699
Score = 43.9 bits (102), Expect = 6e-04
Identities = 55/207 (26%), Positives = 87/207 (42%), Gaps = 30/207 (14%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRV 570
T+V VS+T T + K ++ + E F+ ++ +++AL + I
Sbjct: 16870 TTVWDVVSATVARTTLKVTKLKTGT--------EYQFRIFA-ENRYGQSFALESDPIVAQ 16920
Query: 571 ETHATATPFSKETPSNPVATVKAGER---QWCDVGIFKNNTALVSQFYLLPKGKQSI--S 625
+ P P P AT + + QW + N + V ++L K + SI +
Sbjct: 16921 YPYKEPGP-----PGTPFATAISKDSMVIQWHEP--VNNGGSPVIGYHLERKERNSILWT 16973
Query: 626 KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF----KTCIPGFPGAP 681
KV + D + K Q+L G Y FRV A N G+G SK SE C P PG P
Sbjct: 16974 KVNKTIIHD-TQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDP--PGTP 17030
Query: 682 SAVRISKNVEGIHLSWEPPTSPSGNIL 708
+ + +N I L W P G+++
Sbjct: 17031 EPIMVKRN--EITLQWTKPVYDGGSMI 17055
Score = 43.1 bits (100), Expect = 0.001
Identities = 27/67 (40%), Positives = 35/67 (52%), Gaps = 3/67 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGF-PGAPSAVRI-SKNVEGIHLSWEP 699
L+ G Y+FR AIN GIGP S+ S+ + P F PG PS + K I L W+P
Sbjct: 9171 LLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKP 9230
Query: 700 PTSPSGN 706
P G+
Sbjct: 9231 PAKDGGS 9237
Score = 43.1 bits (100), Expect = 0.001
Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 9/102 (8%)
Query: 611 VSQFYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKIS 668
+S + + + K+S+ ++V V + LK L+ G Y+FRV A+N G S+ S
Sbjct: 22774 ISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22833
Query: 669 EFKTC-----IPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
F +C PG P AP V +K+ I L+W P G
Sbjct: 22834 NFISCREPSYTPGPPSAPRVVDTTKH--SISLAWTKPMYDGG 22873
Score = 42.7 bits (99), Expect = 0.001
Identities = 53/215 (24%), Positives = 92/215 (42%), Gaps = 38/215 (17%)
Query: 581 KETPSNPVATVK----AGERQ--WCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADVPD 634
++TP V ++ GE+ W D + N+ Y++ K + S++ A + D
Sbjct: 21552 QDTPGKVVGPIRFTNITGEKMTLWWDAPL--NDGCAPITHYIIEK--RETSRLAWALIED 21607
Query: 635 ------YSLLKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAV 684
Y+ +K L+ G Y+FRV+A+N G+G P +++ + +P PG P
Sbjct: 21608 KCEAQSYTAIK---LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPS 21664
Query: 685 RISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVT 744
I+ N I L+W P S G+ E Y+ R + +++ R +T VT
Sbjct: 21665 NITGN--SITLTWARPESDGGS--EIQQYILERREKKSTRWVKVISKRPIS--ETRFKVT 21718
Query: 745 AGQLANAHIDYTSRPAIVFRISAKNEKGYGPATQV 779
N + F + A+N G GPA+ +
Sbjct: 21719 GLTEGNEY---------EFHVMAENAAGVGPASGI 21744
Score = 42.4 bits (98), Expect = 0.002
Identities = 52/200 (26%), Positives = 79/200 (39%), Gaps = 23/200 (11%)
Query: 530 KTESSSTNGAVVKDETSLTTFSTKSEVDET-----------YALPATKISR--VETHATA 576
K E+S TN +V + TTF + V + Y + +S V H
Sbjct: 21199 KRETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFR 21258
Query: 577 TPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSI--SKVGNADVPD 634
P P T W D ++ + V+ F++ K + SI KV + +
Sbjct: 21259 IPGPPGKPVIYNVTSDGMSLTW-DAPVYDGGSE-VTGFHVEKKERNSILWQKVNTSPISG 21316
Query: 635 YSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEG 692
+ LV G Y+FRV A N G+ S S+F + PG P + +++ E
Sbjct: 21317 REY-RATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTR--ET 21373
Query: 693 IHLSWEPPTSPSGN-ILEYS 711
I L W PP G+ I+ YS
Sbjct: 21374 ITLKWNPPLRDGGSKIVGYS 21393
Score = 41.6 bits (96), Expect = 0.003
Identities = 34/99 (34%), Positives = 48/99 (48%), Gaps = 11/99 (11%)
Query: 614 FYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF- 670
++L K K SI K+ + D + K L G Y F+V+A N GIG SK+SE
Sbjct: 18042 YHLEQKEKNSILWVKLNKTPIQD-TKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECF 18100
Query: 671 ---KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
C P PG P A+ I++N + L W+ P G+
Sbjct: 18101 VARDPCDP--PGRPEAIVITRN--NVTLKWKKPAYDGGS 18135
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/76 (34%), Positives = 37/76 (48%), Gaps = 8/76 (10%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHL 695
Q L+ G Y FR+AA N G+GPF + SE +P P ++KN + L
Sbjct: 10181 QGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNT--VTL 10238
Query: 696 SWEPPTSPSGN-ILEY 710
+W PP G+ I+ Y
Sbjct: 10239 TWNPPKYDGGSEIINY 10254
Score = 41.2 bits (95), Expect = 0.004
Identities = 26/77 (33%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L G Y+FRV A N G+GP ++ + +PG PG P ++K + +
Sbjct: 14722 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTK--DSMT 14779
Query: 695 LSWEPPTSPSGN-ILEY 710
+SW P S G+ IL Y
Sbjct: 14780 ISWHEPLSDGGSPILGY 14796
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/79 (34%), Positives = 34/79 (43%), Gaps = 7/79 (8%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L+ G+ Y+FRV AIN G+GP S S+ T PG P L
Sbjct: 9884 KVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLE 9943
Query: 697 WEPPTSPSGN-----ILEY 710
W PP G+ I+EY
Sbjct: 9944 WSPPLKDGGSKVTGYIVEY 9962
Score = 40.0 bits (92), Expect = 0.008
Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 4/74 (5%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPF--SKISEFKTCIPGFPGAPSAVRI-SKNVEG 692
S K L G Y FRVAA N GIG + S++ E ++ I PG P ++I + +G
Sbjct: 23392 STFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI-RIPGPPETLQIFDVSRDG 23450
Query: 693 IHLSWEPPTSPSGN 706
+ L+W PP G+
Sbjct: 23451 MTLTWYPPEDDGGS 23464
Score = 39.7 bits (91), Expect = 0.011
Identities = 37/106 (34%), Positives = 53/106 (50%), Gaps = 13/106 (12%)
Query: 615 YLLPKGKQSISK----VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG---PFSKI 667
Y+L K ++++SK V + Y+ + DL+ G Y FRV+A N GIG P SK
Sbjct: 10548 YILEK-RETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKP 10606
Query: 668 SEFKTCI--PGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN-ILEY 710
K I P P P A+ + N + L+W+PP G+ IL Y
Sbjct: 10607 VFAKDPIAKPSPPVNPEAIDTTCN--SVDLTWQPPRHDGGSKILGY 10650
Score = 38.5 bits (88), Expect = 0.025
Identities = 40/147 (27%), Positives = 59/147 (40%), Gaps = 34/147 (23%)
Query: 643 LVPGTGYRFRVAAINGCGIG------PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
L+ G Y FRV+A+N G G P + F PG P P ++KN + S
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGP--PGPPEKPEVSNVTKNTATV--S 14094
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTS-----CIVTAGQLANA 751
W+ P G+ E + Y R + +R +KT C VT Q +
Sbjct: 14095 WKRPVDDGGS--EITGYHVERREKKS--------LRWVRAIKTPVSDLRCKVTGLQEGST 14144
Query: 752 HIDYTSRPAIVFRISAKNEKGYGPATQ 778
+ FR+SA+N G GP ++
Sbjct: 14145 Y---------EFRVSAENRAGIGPPSE 14162
Score = 37.7 bits (86), Expect = 0.042
Identities = 39/145 (26%), Positives = 62/145 (42%), Gaps = 25/145 (17%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEF-KTCIP-GFPGAPSAVRISKNVE-GIHLSWE 698
D+V G Y FRV A N G+G S + F K P P P + S + + L WE
Sbjct: 6757 DVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWE 6816
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLK----TSCIVTAGQLANAHID 754
PP G+ + Y+ R + +DN I C +K + VT + N ++
Sbjct: 6817 PPLKDGGSPI--LGYIIERCEEGKDN-------WIRCNMKLVPELTYKVTGLEKGNKYL- 6866
Query: 755 YTSRPAIVFRISAKNEKGYGPATQV 779
+R+SA+N+ G +++
Sbjct: 6867 --------YRVSAENKAGVSDPSEI 6883
Score = 37.7 bits (86), Expect = 0.042
Identities = 28/71 (39%), Positives = 35/71 (49%), Gaps = 3/71 (4%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IPGFPGAPSAVRIS-KNVEGIHLSWEPP 700
L+ G Y FRV A N G G FS S+ KT P P P R++ + I L WEPP
Sbjct: 8469 LLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEPP 8528
Query: 701 T-SPSGNILEY 710
+ G I+ Y
Sbjct: 8529 AFNGGGEIVGY 8539
Score = 37.7 bits (86), Expect = 0.042
Identities = 23/70 (32%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVE-GIHL 695
K L G Y F V A N G+GP S IS C PG P+ V+++ + + L
Sbjct: 21716 KVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSL 21775
Query: 696 SWEPPTSPSG 705
W P G
Sbjct: 21776 EWSKPVFDGG 21785
Score = 37.4 bits (85), Expect = 0.055
Identities = 50/230 (21%), Positives = 97/230 (42%), Gaps = 26/230 (11%)
Query: 495 VGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKS 554
+ + + D++ +PE S + T +V ++ ++ + T VKD T T+
Sbjct: 7596 INITKNTADLKWTVPEKDGGSPI--TNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7653
Query: 555 E-----VDETYALPATKISRVETHATATP-FSKETPSNPVATVKAGER----QWCDVGIF 604
V A+ + + +E A F+ P +A V +R +W
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPP--- 7710
Query: 605 KNNTALVSQFYLLPKGKQSIS---KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGI 661
KN+ Q Y++ K ++ + K G PD + + D++ GT +F+V A N G+
Sbjct: 7711 KNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF-RVTDVIEGTEVQFQVRAENEAGV 7769
Query: 662 GPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHLSWEPPTSPSGN 706
G S+ +E + P +P + + +V + I ++W+PP G+
Sbjct: 7770 GHPSEPTEILSIED--PTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGS 7817
Score = 37.4 bits (85), Expect = 0.055
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 6/67 (8%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSK----ISEFKTCIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FRV A N G GP ++ I++ K PG P P ++SK E + + W
Sbjct: 11863 LIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK--EEMTVVWN 11920
Query: 699 PPTSPSG 705
PP G
Sbjct: 11921 PPEYDGG 11927
Score = 37.4 bits (85), Expect = 0.055
Identities = 39/135 (28%), Positives = 56/135 (41%), Gaps = 18/135 (13%)
Query: 649 YRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVE-GIHLSWEPPTSPSG 705
Y FRV+A N G+G P +K C P F PG P+ I + I L+W P G
Sbjct: 17392 YEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGG 17451
Query: 706 N-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFR 764
+ IL Y + + + Q+V +T VT +++ T R
Sbjct: 17452 SEILGY----VVEICKADEEEWQIVTP------QTGLRVTRFEISK----LTEHQEYKIR 17497
Query: 765 ISAKNEKGYGPATQV 779
+ A N+ G G AT V
Sbjct: 17498 VCALNKVGLGEATSV 17512
Score = 37.4 bits (85), Expect = 0.055
Identities = 25/77 (32%), Positives = 36/77 (46%), Gaps = 10/77 (12%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGI------GPFSKISEFKTCIPGFPGAPSAVRISKNVEG 692
K L+PG Y FRV A+N GI GP + + +K PG P P I+K +
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKP--PGPPSTPEVSAITK--DS 18420
Query: 693 IHLSWEPPTSPSGNILE 709
+ ++W P G +E
Sbjct: 18421 MVVTWARPVDDGGTEIE 18437
Score = 37.4 bits (85), Expect = 0.055
Identities = 40/141 (28%), Positives = 57/141 (40%), Gaps = 20/141 (14%)
Query: 641 QDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGF-PGAPSAVRISKNVEGIHLSWE 698
++L G Y FRV A N GIG P K P PG + V +++N I WE
Sbjct: 18763 ENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATI--KWE 18820
Query: 699 PPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSR 758
P S G+ + + Y+ ++Q S+ K S L T+
Sbjct: 18821 KPESDGGS--KITGYV----VEMQTKGSE----------KWSTCTQVKTLEATISGLTAG 18864
Query: 759 PAIVFRISAKNEKGYGPATQV 779
VFR++A NEKG Q+
Sbjct: 18865 EEYVFRVAAVNEKGRSDPRQL 18885
Score = 37.0 bits (84), Expect = 0.072
Identities = 38/140 (27%), Positives = 59/140 (42%), Gaps = 27/140 (19%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISE-------FKTCIPGFPGAPSAVRISKNVEGIHL 695
L G+ Y FRVAA N G +++I + F T PG P A + V ++K + L
Sbjct: 7650 LTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTT--PGPPYALAVVDVTKR--HVDL 7705
Query: 696 SWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WEPP + G ++ + + +L + G TAG N + D
Sbjct: 7706 KWEPPKNDGGRPIQ---------RYVIEKKERLGTRWVKAG------KTAGPDCNFRVTD 7750
Query: 755 YTSRPAIVFRISAKNEKGYG 774
+ F++ A+NE G G
Sbjct: 7751 VIEGTEVQFQVRAENEAGVG 7770
Score = 36.6 bits (83), Expect = 0.094
Identities = 28/99 (28%), Positives = 45/99 (45%), Gaps = 9/99 (9%)
Query: 615 YLLPKGKQSISKVGNADVPDYSLLKKQD---LVPGTGYRFRVAAINGCGIGPFSK----I 667
Y++ K S K +V + ++ K+ L+P Y FRV A+N GI K +
Sbjct: 9035 YVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVV 9094
Query: 668 SEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGN 706
+ +PG PG P + +K + +SW PP G+
Sbjct: 9095 IQDPYRLPGPPGKPKVLARTKG--SMLVSWTPPLDNGGS 9131
Score = 36.6 bits (83), Expect = 0.094
Identities = 27/74 (36%), Positives = 33/74 (44%), Gaps = 8/74 (10%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLSW 697
LVP Y+FR+ A N G+ S SE C P PG + ISK + + L W
Sbjct: 23897 LVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISK--DSVTLQW 23954
Query: 698 EPPTSPSG-NILEY 710
E P G IL Y
Sbjct: 23955 EKPECDGGKEILGY 23968
Score = 36.2 bits (82), Expect = 0.12
Identities = 23/66 (34%), Positives = 34/66 (51%), Gaps = 4/66 (6%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTC-IP-GFPGAPSAVRISKNVEGIHLSWEPP 700
LV G Y FR+ A+N G P SK +E+ T +P PG P + ++K+ + L W P
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKST--VSLIWARP 12716
Query: 701 TSPSGN 706
G+
Sbjct: 12717 KHDGGS 12722
Score = 35.8 bits (81), Expect = 0.16
Identities = 40/138 (28%), Positives = 52/138 (37%), Gaps = 29/138 (21%)
Query: 646 GTGYRFRVAAINGCGIG-------PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSW 697
G Y FRV+A N G G P S++ PG P V I+ N G+ L+W
Sbjct: 6660 GVEYLFRVSARNRVGTGEPVETDNPVEARSKYDV-----PGPPLNVTITDVNRFGVSLTW 6714
Query: 698 EPPTSPSG-NILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
EPP G I Y L +T+ D T+ V A L+ D
Sbjct: 6715 EPPEYDGGAEITNYVIELRDKTSIRWD---------------TAMTVRAEDLSATVTDVV 6759
Query: 757 SRPAIVFRISAKNEKGYG 774
FR+ A+N G G
Sbjct: 6760 EGQEYSFRVRAQNRIGVG 6777
Score = 35.8 bits (81), Expect = 0.16
Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISK-NVEGIHLSWEPP 700
L+PG Y FRV A N GI + P G P P R++K N + I ++W+ P
Sbjct: 12559 LIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP 12618
Query: 701 TSPSGN 706
S G+
Sbjct: 12619 DSDGGS 12624
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/72 (34%), Positives = 32/72 (44%), Gaps = 4/72 (5%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF--PGAPSAVRISKNVEGIHLS 696
K L G Y FRV AIN G+G S SE + PG P + I++N + L
Sbjct: 13739 KVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRN--SVTLI 13796
Query: 697 WEPPTSPSGNIL 708
W P G+ L
Sbjct: 13797 WTEPKYDGGHKL 13808
Score = 35.8 bits (81), Expect = 0.16
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 7/73 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEF-KTC----IPGFPGAPSAVRISKNVEG 692
L+ L G Y FRVAA N G+G S+ S F + C PG P P S++
Sbjct: 18464 LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS--S 18521
Query: 693 IHLSWEPPTSPSG 705
+ L+W P G
Sbjct: 18522 VSLAWSKPIYDGG 18534
Score = 35.8 bits (81), Expect = 0.16
Identities = 22/69 (31%), Positives = 33/69 (47%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEGIHLS 696
+L GY FRV+A N GI ++S PG PG P+ ++K + ++
Sbjct: 24290 NLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTK--DSCVVA 24347
Query: 697 WEPPTSPSG 705
W+PP S G
Sbjct: 24348 WKPPASDGG 24356
Score = 35.4 bits (80), Expect = 0.21
Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)
Query: 642 DLVPGTGYRFRVAAINGCGIGPFSKISE-FKTCIPG-FPGAPSAVR-ISKNVEGIHLSWE 698
DLV G Y F+V A N CG G + + E P P P V+ + I L+W+
Sbjct: 7053 DLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWD 7112
Query: 699 PPTSPSGN 706
PP + G+
Sbjct: 7113 PPKNDGGS 7120
Score = 35.4 bits (80), Expect = 0.21
Identities = 25/73 (34%), Positives = 33/73 (45%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGP----FSKISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L G Y FRV A N G+GP +++ K P PG P I++N +
Sbjct: 11166 LKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATV 11225
Query: 694 HLSWEPPTSPSGN 706
SW P S G+
Sbjct: 11226 --SWTLPKSDGGS 11236
Score = 35.4 bits (80), Expect = 0.21
Identities = 24/77 (31%), Positives = 38/77 (49%), Gaps = 7/77 (9%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGIH 694
K L+ G Y FR+ A+N G+G P +++ +P P AP ++K + +
Sbjct: 16200 KVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTK--DSMI 16257
Query: 695 LSWEPPTSPSGN-ILEY 710
+ WE P S G+ IL Y
Sbjct: 16258 VVWERPASDGGSEILGY 16274
Score = 35.4 bits (80), Expect = 0.21
Identities = 36/132 (27%), Positives = 54/132 (40%), Gaps = 18/132 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
DL T + FRV A N GIG P K P +++ S I LSW P
Sbjct: 20931 DLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSWTKP 20989
Query: 701 TSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRPA 760
G+++ + Y+ R + + S + G+ +C + QL +
Sbjct: 20990 DFDGGSVI--TEYVVERKGKGEQTWS-------HAGISKTCEIEVSQLKEQSV------- 21033
Query: 761 IVFRISAKNEKG 772
+ FR+ AKNEKG
Sbjct: 21034 LEFRVFAKNEKG 21045
Score = 35.0 bits (79), Expect = 0.27
Identities = 26/70 (37%), Positives = 33/70 (47%), Gaps = 7/70 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIGP-FSKISEFKTCIPGFPGAPSAVR----ISKNVEGIHLS 696
DL+ Y FRV A N GIGP I P +P P I+KN +HLS
Sbjct: 9477 DLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNT--VHLS 9534
Query: 697 WEPPTSPSGN 706
W+PP + G+
Sbjct: 9535 WKPPKNDGGS 9544
Score = 34.7 bits (78), Expect = 0.36
Identities = 60/243 (24%), Positives = 94/243 (38%), Gaps = 34/243 (13%)
Query: 502 LDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVV-KDETSLTTFSTKSEVDETY 560
LDV +S+ + T+ ++ S ++ K ETS ++ SE ++
Sbjct: 13973 LDVPGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSC 14032
Query: 561 ALPATKISRVETH----ATATPFSKETP--SNPVATVKA----GERQWCDVGIFKNNTAL 610
ATK+ + + + + K P S PV V G + +V NTA
Sbjct: 14033 RHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTAT 14092
Query: 611 VSQ-------------FYLLPKGKQSISKVGNADVPDYSL-LKKQDLVPGTGYRFRVAAI 656
VS +++ + K+S+ V P L K L G+ Y FRV+A
Sbjct: 14093 VSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14152
Query: 657 NGCGIGPFSKISEF-----KTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSGNILEYS 711
N GIGP S+ S+ PG P P +K + L+W P G LE +
Sbjct: 14153 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTK--KSASLAWGKPHYDGG--LEIT 14208
Query: 712 AYL 714
Y+
Sbjct: 14209 GYV 14211
Score = 34.3 bits (77), Expect = 0.46
Identities = 37/138 (26%), Positives = 54/138 (39%), Gaps = 24/138 (17%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLS 696
K ++L G Y FRV A N G+G P + K P P P V ++ + L
Sbjct: 17678 KVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEP--PSPPGKVTLTDVSQTSASLM 17735
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI-D 754
WE P G+ +L Y + + G + IV ++ NA +
Sbjct: 17736 WEKPEHDGGSRVLGYVVEMQPK------------------GTEKWSIVAESKVCNAVVTG 17777
Query: 755 YTSRPAIVFRISAKNEKG 772
+S FR+ A NEKG
Sbjct: 17778 LSSGQEYQFRVKAYNEKG 17795
Score = 33.9 bits (76), Expect = 0.61
Identities = 46/180 (25%), Positives = 70/180 (38%), Gaps = 24/180 (13%)
Query: 611 VSQFYLLPKGKQSIS--KVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PF 664
++ ++L K K S V + +P+ + K Q+L+P Y+FRV A N GIG P
Sbjct: 11930 ITGYFLEKKEKHSTRWVPVNKSAIPERRM-KVQNLLPDHEYQFRVKAENEIGIGEPSLPS 11988
Query: 665 SKISEFKTCIPGFPGAPSAVRISKNVE-GIHLSWEPPTSPSGNILEYSAYLAIRTAQIQD 723
+ P PG P+ R+ + I L W P G Y+ +I D
Sbjct: 11989 RPVVAKDPIEP--PGPPTNFRVVDTTKHSITLGWGKPVYDGG--APIIGYVVEMRPKIAD 12044
Query: 724 NPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTS---RPAIVFRISAKNEKGYGPATQVR 780
+ R C A QL TS FR+ A+N+ G G +++
Sbjct: 12045 ASPDEGWKR--CN-------AAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELK 12095
Score = 33.9 bits (76), Expect = 0.61
Identities = 38/137 (27%), Positives = 52/137 (37%), Gaps = 22/137 (16%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIG-PFSKISEFKTC-IPGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG P K +P PG + +++N + LS
Sbjct: 16596 KIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRN--SVSLS 16653
Query: 697 WEPPTSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDY 755
W P G+ I++Y +V M+ K S L +
Sbjct: 16654 WTKPEHDGGSKIIQY-----------------IVEMQAKHSEKWSECARVKSLQAVITNL 16696
Query: 756 TSRPAIVFRISAKNEKG 772
T +FR+ A NEKG
Sbjct: 16697 TQGEEYLFRVVAVNEKG 16713
Score = 33.5 bits (75), Expect = 0.79
Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 2/69 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRISKNVEG-IHLSWEPP 700
L+ G Y+FRV A N G GP +I P G P +P + ++ + I L W+ P
Sbjct: 8762 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 8821
Query: 701 TSPSGNILE 709
S G+ ++
Sbjct: 8822 RSNGGSPIQ 8830
Score = 33.5 bits (75), Expect = 0.79
Identities = 38/126 (30%), Positives = 59/126 (46%), Gaps = 22/126 (17%)
Query: 651 FRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-EGIHLSWEPPTSPSGNILE 709
+ + A N G SK + K + PG P++V+I+K + LSWEPP G+ E
Sbjct: 12869 YTITAENSSG----SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGS--E 12922
Query: 710 YSAYLAIRTAQIQDNPSQL-VFMRIYCGLKTSCIVTAGQLANAHIDYTSRPAIVFRISAK 768
+ Y+ + + N +Q+ + I TSC V +L H +Y FRI A+
Sbjct: 12923 ITNYIVDKRETSRPNWAQVSATVPI-----TSCSVE--KLIEGH-EYQ------FRICAE 12968
Query: 769 NEKGYG 774
N+ G G
Sbjct: 12969 NKYGVG 12974
Score = 33.5 bits (75), Expect = 0.79
Identities = 26/81 (32%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIP-GFPGAPSAVRI-SKNVEGIHLS 696
K L+ G Y FRV +N G+G + K P P P+++ I S E + L
Sbjct: 19446 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLC 19505
Query: 697 WEPPTSPSGNILEYSAYLAIR 717
W P S G+ E S Y+ R
Sbjct: 19506 WSRPESDGGS--EISGYIIER 19524
Score = 33.1 bits (74), Expect = 1.0
Identities = 25/74 (33%), Positives = 31/74 (41%), Gaps = 7/74 (9%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTC-----IPGFPGAPSAVRISKNVEG 692
LK L GT Y FRV AIN G G S S+ PG P P +++
Sbjct: 13050 LKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRS--S 13107
Query: 693 IHLSWEPPTSPSGN 706
+ LSW P G+
Sbjct: 13108 VSLSWGKPAYDGGS 13121
Score = 33.1 bits (74), Expect = 1.0
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 20/143 (13%)
Query: 639 KKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCI--PGFPGAPSAVRISKNVEGIHLS 696
K L G Y FRV A N GIG ++ +E P PG + + +++N + LS
Sbjct: 15514 KVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRN--SVSLS 15571
Query: 697 WEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYT 756
WE P G+ Y+ + D + +++ T +T G +
Sbjct: 15572 WEKPEHDGGS--RILGYIVEMQTKGSDKWATCATVKV-----TEATIT-GLIQGEEYS-- 15621
Query: 757 SRPAIVFRISAKNEKGYGPATQV 779
FR+SA+NEKG Q+
Sbjct: 15622 ------FRVSAQNEKGISDPRQL 15638
Score = 33.1 bits (74), Expect = 1.0
Identities = 65/270 (24%), Positives = 98/270 (36%), Gaps = 46/270 (17%)
Query: 511 TSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDE---TYALPATKI 567
T VS+TV+ T V + T E +K E F +D T LP T
Sbjct: 20121 TEVSATVARTMMKVMKLTTGEEYQFR----IKAENR---FGISDHIDSACVTVKLPYT-- 20171
Query: 568 SRVETHATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSIS-K 626
TP TP T ++ W + N + V ++L K + SI +
Sbjct: 20172 ---------TPGPPSTPWVTNVTRESITVGWHEP--VSNGGSAVVGYHLEMKDRNSILWQ 20220
Query: 627 VGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIG----PFSKISEFKTCIPGFPGAPS 682
N V + K + G Y FRV A N G+G P + C P P
Sbjct: 20221 KANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEP--PRNVR 20278
Query: 683 AVRISKNVEGIHLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCI 742
ISKN + LSW+ P G+ + + Y+ R +D P + + +
Sbjct: 20279 ITDISKN--SVSLSWQQPAFDGGS--KITGYIVER----RDLPDGRWTKASFTNVTETQF 20330
Query: 743 VTAGQLANAHIDYTSRPAIVFRISAKNEKG 772
+ +G N+ + FR+ A+N G
Sbjct: 20331 IISGLTQNSQYE--------FRVFARNAVG 20352
Score = 33.1 bits (74), Expect = 1.0
Identities = 46/200 (23%), Positives = 72/200 (36%), Gaps = 28/200 (14%)
Query: 513 VSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVET 572
V+S+V TQ VT T E S F SE + P +
Sbjct: 22294 VNSSVKRTQIKVTHLTKYMEYS---------------FRVSSENRFGVSKPLESAPIIAE 22338
Query: 573 HATATPFSKETPSNPVATVKAGERQWCDVGIFKNNTALVSQFYLLPKGKQSISKVGNADV 632
H P + P + A +W + + + + + +++ K + +I V V
Sbjct: 22339 HPFVPPSAPTRPEVYHVSANAMSIRWEEP--YHDGGSKIIGYWVEKKERNTILWVKENKV 22396
Query: 633 PDYSL-LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPG-----FPGAPSAVRI 686
P K LV G Y+FR A+N G+ SK SE I PG P +
Sbjct: 22397 PCLECNYKVTGLVEGLEYQFRTYALNAAGV---SKASEASRPIMAQNPVDAPGRPEVTDV 22453
Query: 687 SKNVEGIHLSWEPPTSPSGN 706
+++ + L W P G+
Sbjct: 22454 TRST--VSLIWSAPAYDGGS 22471
Score = 32.7 bits (73), Expect = 1.4
Identities = 16/54 (29%), Positives = 27/54 (50%)
Query: 616 LLPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE 669
+ P G + +V + + D ++ +VP Y RV A+N G+ S+ISE
Sbjct: 7826 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISE 7879
Score = 32.7 bits (73), Expect = 1.4
Identities = 39/144 (27%), Positives = 61/144 (42%), Gaps = 26/144 (18%)
Query: 643 LVPGTGYRFRVAAINGCGIG-PFSKISEFKT---CIPGFPGAPSAVRISKNVEGIHLSWE 698
L+ G Y FR+ A N GIG P E +PG P P+ +++N + ++WE
Sbjct: 9784 LLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRN--SMTVNWE 9841
Query: 699 PPT----SP-SGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
P SP +G LE + R ++ +P + M + K + ++
Sbjct: 9842 EPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDP--IKAMTLGVSYKVTGLIEGS------- 9892
Query: 754 DYTSRPAIVFRISAKNEKGYGPAT 777
DY FR+ A N G GPA+
Sbjct: 9893 DYQ------FRVYAINAAGVGPAS 9910
Score = 32.0 bits (71), Expect = 2.3
Identities = 38/139 (27%), Positives = 59/139 (42%), Gaps = 18/139 (12%)
Query: 636 SLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGI 693
+L + LV GT Y FRV N GIG + S+ + +P P V ++K+ +
Sbjct: 23097 TLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKST--V 23154
Query: 694 HLSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHI 753
L+WE P G+ L A + + +M++ LK + + N
Sbjct: 23155 TLAWEKPLYDGGSRLTGYVLEACKAGTER-------WMKVVT-LKPTVLEHTVTSLNEGE 23206
Query: 754 DYTSRPAIVFRISAKNEKG 772
Y +FRI A+NEKG
Sbjct: 23207 QY------LFRIRAQNEKG 23219
Score = 31.6 bits (70), Expect = 3.0
Identities = 25/75 (33%), Positives = 33/75 (44%), Gaps = 9/75 (12%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGF-----PGAPSAVRIS-KNVE 691
L K +L+ Y FRV A N G+GP E KT I PG P + I+ K
Sbjct: 11562 LIKANLLANNEYYFRVCAENKVGVGP---TIETKTPILAINPIDRPGEPENLHIADKGKT 11618
Query: 692 GIHLSWEPPTSPSGN 706
++L W P G+
Sbjct: 11619 FVYLKWRRPDYDGGS 11633
Score = 31.6 bits (70), Expect = 3.0
Identities = 31/98 (31%), Positives = 42/98 (42%), Gaps = 11/98 (11%)
Query: 614 FYLLPKGKQSI--SKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE-- 669
++L K + SI SK + D + +K L G Y +RV A N GIG SK E
Sbjct: 19124 YHLEYKERSSILWSKANKILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPV 19182
Query: 670 --FKTCIPGFPGAPSAVRISKNVEGIHLSWEPPTSPSG 705
C P PG P I++ + + L W P G
Sbjct: 19183 PARDPCDP--PGQPEVTNITR--KSVSLKWSKPHYDGG 19216
Score = 30.8 bits (68), Expect = 5.1
Identities = 20/71 (28%), Positives = 32/71 (45%), Gaps = 7/71 (9%)
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISKNV-----EGIHL 695
+DL+P Y FRV A+N G G + ++ I P P + V E + +
Sbjct: 8044 KDLIPNGEYFFRVKAVNKVGGGEYIELK--NPVIAQDPKQPPDPPVDVEVHNPTAEAMTI 8101
Query: 696 SWEPPTSPSGN 706
+W+PP G+
Sbjct: 8102 TWKPPLYDGGS 8112
Score = 30.8 bits (68), Expect = 5.1
Identities = 36/139 (25%), Positives = 52/139 (37%), Gaps = 20/139 (14%)
Query: 637 LLKKQDLVPGTGYRFRVAAINGCGIGPFSKISE--FKTCIPGFPGAPSAVRISKNVEGIH 694
+ K DL G Y FRV+A+N G+G ++ E T P P V SK+
Sbjct: 22009 IFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKS--SAV 22066
Query: 695 LSWEPPTSPSGNILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHID 754
L+W P G+ + YL + D + G T +L
Sbjct: 22067 LAWLKPDHDGGS--RITGYLLEMRQKGSD-------FWVEAGHTKQLTFTVERL------ 22111
Query: 755 YTSRPAIVFRISAKNEKGY 773
+ FR+ AKN+ GY
Sbjct: 22112 -VEKTEYEFRVKAKNDAGY 22129
Score = 30.4 bits (67), Expect = 6.7
Identities = 22/69 (31%), Positives = 29/69 (42%), Gaps = 7/69 (10%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-----PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLS 696
+LVPG Y FRV A+N G G P ++ P P ++KN L+
Sbjct: 12264 NLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKN--SATLA 12321
Query: 697 WEPPTSPSG 705
W PP G
Sbjct: 12322 WLPPLRDGG 12330
Score = 30.4 bits (67), Expect = 6.7
Identities = 39/151 (25%), Positives = 58/151 (38%), Gaps = 21/151 (13%)
Query: 642 DLVPGTGYRFRVAAINGCGIG-PFSKISEFKTCIPGFPGAPSAVRISKNVEGIHLSWEPP 700
+L G Y FRV A N GIG P K P VR S + + W+ P
Sbjct: 13352 NLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVR-SVSKSSCSIGWKKP 13410
Query: 701 TSPSGN-ILEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTSRP 759
S G+ I+ Y + ++N Q V + L + D T
Sbjct: 13411 HSDGGSRIIGY-----VVDFLTEENKWQRVMKSL-------------SLQYSAKDLTEGK 13452
Query: 760 AIVFRISAKNEKGYGPATQVRWLQGNNKKAP 790
FR+SA+NE G G +++ + ++ AP
Sbjct: 13453 EYTFRVSAENENGEGTPSEITVVARDDVVAP 13483
Score = 30.4 bits (67), Expect = 6.7
Identities = 21/73 (28%), Positives = 34/73 (46%), Gaps = 6/73 (8%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIG-PFSK---ISEFKTCIPGFPGAPSAVRISKNVEGI 693
LK L+ G Y FR+ A+N G+G P + + +PG P + I+K + +
Sbjct: 17281 LKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK--DSM 17338
Query: 694 HLSWEPPTSPSGN 706
+ W P S G+
Sbjct: 17339 TVCWNRPDSDGGS 17351
>gi|81158226 neuronal cell adhesion molecule isoform A precursor
[Homo sapiens]
Length = 1304
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRI-SKNVEGIHLSWEPPT 701
L P + Y V +NG G GP S F T G P APS+++I + ++ + L W+PP+
Sbjct: 918 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTP-EGVPSAPSSLKIVNPTLDSLTLEWDPPS 976
Query: 702 SPSGNILEYS 711
P+G + EY+
Sbjct: 977 HPNGILTEYT 986
Score = 31.2 bits (69), Expect = 3.9
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Query: 357 PPAPSQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAP 407
P APS ++++ T +S ++WD S G L + + L YQ +S P
Sbjct: 952 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYT--LKYQPINSTHELGP 1000
>gi|81158224 neuronal cell adhesion molecule isoform B precursor
[Homo sapiens]
Length = 1183
Score = 48.5 bits (114), Expect = 2e-05
Identities = 26/70 (37%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRI-SKNVEGIHLSWEPPT 701
L P + Y V +NG G GP S F T G P APS+++I + ++ + L W+PP+
Sbjct: 902 LEPFSHYTLNVRVVNGKGEGPASPDRVFNTP-EGVPSAPSSLKIVNPTLDSLTLEWDPPS 960
Query: 702 SPSGNILEYS 711
P+G + EY+
Sbjct: 961 HPNGILTEYT 970
Score = 31.2 bits (69), Expect = 3.9
Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%)
Query: 357 PPAPSQVQLIKATTNSFHVKWDEVSTVEGYLLQLSTDLPYQAASSDSSAAP 407
P APS ++++ T +S ++WD S G L + + L YQ +S P
Sbjct: 936 PSAPSSLKIVNPTLDSLTLEWDPPSHPNGILTEYT--LKYQPINSTHELGP 984
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 46.2 bits (108), Expect = 1e-04
Identities = 33/128 (25%), Positives = 59/128 (46%), Gaps = 5/128 (3%)
Query: 584 PSNPVATVKAGERQWCDVGI---FKNNTALVSQFYLLPKGKQSISKVGNADVPDYSLLKK 640
P +PVAT+ ER+ ++ F N+ L+ + + + + + P + +
Sbjct: 593 PEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTV 652
Query: 641 QDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAP--SAVRISKNVEGIHLSWE 698
+ LVP Y+FR+ A+N G G FSK +E + P AP + + + + I + W+
Sbjct: 653 KGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQ 712
Query: 699 PPTSPSGN 706
PP N
Sbjct: 713 PPPESHQN 720
Score = 42.0 bits (97), Expect = 0.002
Identities = 28/73 (38%), Positives = 41/73 (56%), Gaps = 3/73 (4%)
Query: 638 LKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLS 696
+K ++L T Y VAA N G GP S ++ +T P APS+V+ S+ +++S
Sbjct: 1685 VKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQ-QAAPSAPSSVKFSELTTTSVNVS 1743
Query: 697 WEPPTSPSGNILE 709
WE P P+G ILE
Sbjct: 1744 WEAPQFPNG-ILE 1755
Score = 38.9 bits (89), Expect = 0.019
Identities = 33/136 (24%), Positives = 51/136 (37%), Gaps = 25/136 (18%)
Query: 649 YRFRVAAINGCGIGPFSKISEFKTCIPGFPGAPSAVRISK-NVEGIHLSWEPPTSPSGNI 707
Y +V A G G S + + PG P + + + L W+PP +P+G I
Sbjct: 1272 YEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGII 1331
Query: 708 LEYSAYLAIRTAQIQDNPSQLVFMRIYCGLKTSCIVTAGQLANAHIDYTS-----RPAIV 762
L Y + T T+ T LA + YT+ +
Sbjct: 1332 LAYQITHRLNTT-------------------TANTATVEVLAPSARQYTATGLKPESVYL 1372
Query: 763 FRISAKNEKGYGPATQ 778
FRI+A+ KG+G A +
Sbjct: 1373 FRITAQTRKGWGEAAE 1388
Score = 37.0 bits (84), Expect = 0.072
Identities = 22/66 (33%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 643 LVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPG-APSAVRISKN-VEGIHLSWEPP 700
L P T Y+FRV A N G FS+ SE T + P AP+ + ++ + + + W+PP
Sbjct: 1466 LKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPP 1525
Query: 701 TSPSGN 706
N
Sbjct: 1526 AEDKIN 1531
Score = 34.7 bits (78), Expect = 0.36
Identities = 28/88 (31%), Positives = 43/88 (48%), Gaps = 9/88 (10%)
Query: 617 LPKGKQSISKVGNADVPDYSLLKKQDLVPGTGYRFRVAAINGCGIGPF-SKISEFKTCIP 675
LP G Q + +ADV + L +DL+ T Y VAA N G+G + SK++E+ +
Sbjct: 735 LPVGYQ-FKNITDADVNNLLL---EDLIIWTNYEIEVAAYNSAGLGVYSSKVTEW--TLQ 788
Query: 676 GFPGAP--SAVRISKNVEGIHLSWEPPT 701
G P P + + N I +W P+
Sbjct: 789 GVPTVPPGNVHAEATNSTTIRFTWNAPS 816
Score = 32.0 bits (71), Expect = 2.3
Identities = 27/89 (30%), Positives = 35/89 (39%), Gaps = 3/89 (3%)
Query: 624 ISKVGNADVPDYS--LLKKQDLVPGTGYRFRVAAINGCGIGPFSKISEFKTCIPGFPGAP 681
+SK+ DV S LK +DL G YRFR+ A GP + + G PG P
Sbjct: 1770 VSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRA-KTFTYGPEIEANVTTGPGEGAPGPP 1828
Query: 682 SAVRISKNVEGIHLSWEPPTSPSGNILEY 710
I + I + W G I Y
Sbjct: 1829 GVPIIVRYSSAIAIHWSSGDPGKGPITRY 1857
>gi|239753123 PREDICTED: kelch-like 29 (Drosophila) [Homo sapiens]
Length = 875
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 8/103 (7%)
Query: 8 NWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGD 67
NW VS T VPR RH + V ++ + G G G D + Y+T TNQW A
Sbjct: 662 NWNLVSRMT--VPRCRH-NSLVYDGKIYTLGGLGVAGNVDHVERYDTITNQWEAVA---P 715
Query: 68 IPPGCAAHGFVCDGTRILVFGGMVEYGRYSNEL--YELQASRW 108
+P + G +I VFGG+ E GR + L Y Q + W
Sbjct: 716 LPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTW 758
Score = 43.5 bits (101), Expect = 8e-04
Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 41/220 (18%)
Query: 46 ADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQA 105
A H+ A + P R + G A V G R +V GM + + + Q
Sbjct: 556 AKRYHMLPHARQEMQTPRTRPRLSAG-VAEVIVLVGGRQMV--GMTQRSLVAVTCWNPQN 612
Query: 106 SRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYE 165
++W P + LP R S G+ YL GG+ ES + +V Y+
Sbjct: 613 NKWY--------PLASLPFYDREFFSVVSAGDNIYLSGGM--ESGVTLADVWCYM----- 657
Query: 166 LELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGM-CGARLDDLWQ 224
S + W++ V++ VP R H +++Y K+Y GG+ +D + +
Sbjct: 658 ------SLLDNWNL-VSRMTVPRCR--HNSLVY------DGKIYTLGGLGVAGNVDHVER 702
Query: 225 LDLETMSWSKPETKGTVPLPRSLHTAS--VIGNKMYIFGG 262
D T W + PLP+++H+A+ V G K+Y+FGG
Sbjct: 703 YDTITNQW-----EAVAPLPKAVHSAAATVCGGKIYVFGG 737
>gi|239741555 PREDICTED: kelch repeat and BTB (POZ) domain
containing 9 [Homo sapiens]
Length = 875
Score = 45.8 bits (107), Expect = 2e-04
Identities = 36/103 (34%), Positives = 48/103 (46%), Gaps = 8/103 (7%)
Query: 8 NWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPAVRGD 67
NW VS T VPR RH + V ++ + G G G D + Y+T TNQW A
Sbjct: 662 NWNLVSRMT--VPRCRH-NSLVYDGKIYTLGGLGVAGNVDHVERYDTITNQWEAVA---P 715
Query: 68 IPPGCAAHGFVCDGTRILVFGGMVEYGRYSNEL--YELQASRW 108
+P + G +I VFGG+ E GR + L Y Q + W
Sbjct: 716 LPKAVHSAAATVCGGKIYVFGGVNEAGRAAGVLQSYVPQTNTW 758
Score = 43.5 bits (101), Expect = 8e-04
Identities = 57/220 (25%), Positives = 93/220 (42%), Gaps = 41/220 (18%)
Query: 46 ADELHVYNTATNQWFLPAVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQA 105
A H+ A + P R + G A V G R +V GM + + + Q
Sbjct: 556 AKRYHMLPHARQEMQTPRTRPRLSAG-VAEVIVLVGGRQMV--GMTQRSLVAVTCWNPQN 612
Query: 106 SRWLWKKVKPHPPPSGLPPCPRLGHSFSLYGNKCYLFGGLANESEDSNNNVPRYLNDFYE 165
++W P + LP R S G+ YL GG+ ES + +V Y+
Sbjct: 613 NKWY--------PLASLPFYDREFFSVVSAGDNIYLSGGM--ESGVTLADVWCYM----- 657
Query: 166 LELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGM-CGARLDDLWQ 224
S + W++ V++ VP R H +++Y K+Y GG+ +D + +
Sbjct: 658 ------SLLDNWNL-VSRMTVPRCR--HNSLVY------DGKIYTLGGLGVAGNVDHVER 702
Query: 225 LDLETMSWSKPETKGTVPLPRSLHTAS--VIGNKMYIFGG 262
D T W + PLP+++H+A+ V G K+Y+FGG
Sbjct: 703 YDTITNQW-----EAVAPLPKAVHSAAATVCGGKIYVFGG 737
>gi|158508542 kelch-like 33 [Homo sapiens]
Length = 453
Score = 45.4 bits (106), Expect = 2e-04
Identities = 44/151 (29%), Positives = 63/151 (41%), Gaps = 19/151 (12%)
Query: 4 PSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIA-DELHVYNTATNQWFLP 62
PS +W ++ P+ +AR VA+ + GG + +A D + YN N W P
Sbjct: 217 PSQEDWEEMA----PLSQARSLFSLVALDGKLYALGGRHNDVALDSVETYNPELNVW-RP 271
Query: 63 AVRGDIPPGCAAHGFVCDGTRILVFGGMVEYGRYSNELYELQASRWLWKKVKPHPPPSGL 122
A +P C AH ++ V GG G+Y L K P + L
Sbjct: 272 APA--LPAPCFAHAAAILEGQLYVSGGCGGTGQYLASLMHYDP--------KLEKPGTFL 321
Query: 123 PPC--PRLGHSFSLYGNKCYLFGGLANESED 151
P PR GH + G + Y+ GGL E+ED
Sbjct: 322 SPMGVPRAGHVMAALGGRLYVAGGL-GETED 351
Score = 34.7 bits (78), Expect = 0.36
Identities = 78/318 (24%), Positives = 116/318 (36%), Gaps = 77/318 (24%)
Query: 4 PSLLNWRRVSSFTGPVPRARHGHRAVAIRELMIIFGGGNEGIADELHVYNTATNQWFLPA 63
P LL+ V + R R RA +++ GG +G+ ++ + + W+ A
Sbjct: 106 PDLLHQLMVEADVPGQERRREPDRA------LVVIGG--DGLRPDMALRQPSRAVWWARA 157
Query: 64 VR-----------GDIP----PGCAAHGFVC-DGTRILVFGGMVEYGRYSNELYEL---Q 104
R G +P PG HG G+ + V GG Y +SN L +
Sbjct: 158 FRCGVGLVRTVEWGQLPALPAPGRFRHGAASLAGSELYVCGGQDFYS-HSNTLASTLRWE 216
Query: 105 ASRWLWKKVKPHPPPSGLPPCPRLGHSFSLYG--NKCYLFGGLANESEDSNNNVPRYLND 162
S+ W+++ P L FSL K Y GG +N+V +
Sbjct: 217 PSQEDWEEMAPLSQARSL---------FSLVALDGKLYALGG-------RHNDVALDSVE 260
Query: 163 FYELELQHGSGVVGWSIPVTKGVVPSPRESHTAVIYCKKDSGSPKMYVFGGMCGARLDDL 222
Y EL V P +P+P +H A I ++YV GG CG L
Sbjct: 261 TYNPELN-----VWRPAPA----LPAPCFAHAAAIL------EGQLYVSGG-CGGTGQYL 304
Query: 223 WQLDLETMSWSKPET-KGTVPLPRSLHTASVIGNKMYIFGGWVPHKGENTETSPHDCEWR 281
L KP T + +PR+ H + +G ++Y+ GG GE +
Sbjct: 305 ASLMHYDPKLEKPGTFLSPMGVPRAGHVMAALGGRLYVAGG----LGETED--------- 351
Query: 282 CTSSFSYLNLDTTEWTTL 299
SF L T WT L
Sbjct: 352 -LLSFEAYELRTDSWTHL 368
>gi|239740773 PREDICTED: similar to diffuse panbronchiolitis critical
region 1 [Homo sapiens]
Length = 1400
Score = 45.4 bits (106), Expect = 2e-04
Identities = 38/164 (23%), Positives = 67/164 (40%), Gaps = 5/164 (3%)
Query: 430 NDTINSTKTEQPATKETS-MKNKPDFKALTDSNAILYPSLASNASNHNSHVVDMLRKNEG 488
N T +ST T P T TS KN +A I ++ ++ S ++
Sbjct: 1058 NTTTSSTVTSVPTTASTSGSKNTTACEATMSETTIA--AITASEDTTVSTQTSVIAAESV 1115
Query: 489 PHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSL- 547
PHT+ ++ V +P+ + S ++ST + KT ++++ TSL
Sbjct: 1116 PHTATKTPTDTTTASVSATVPKNNTLSVITSTPSTAPNTASKTMTTASKTTTTSTITSLP 1175
Query: 548 -TTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVAT 590
T F+T S++ +P + T A +T S T + +T
Sbjct: 1176 TTVFTTTSKITAGSEIPTASTTDSATTAISTKASGTTVESAPST 1219
Score = 33.9 bits (76), Expect = 0.61
Identities = 37/170 (21%), Positives = 67/170 (39%), Gaps = 13/170 (7%)
Query: 434 NSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVVDMLRKNEGPHTSA 493
N+T+ +P K T D K+ TD N P+ N+SN + +++ P S
Sbjct: 150 NTTRHSKPTDKPTGNSKTIDHKSSTD-NHEAPPTSEENSSNQGKDPMIRNQRSVDPADST 208
Query: 494 NVGVLSSCLDVRTVIPETSVSSTVSST-QTMVTQQTIKTESSSTNGAVVKDETSLTTFST 552
S+ T P++ ++ S+T ++ VT+++ KT D+TS ++ T
Sbjct: 209 TTHKESAGKKHITPAPKSKINCRKSTTGKSTVTRKSDKTGRPLEKSMSTLDKTSTSSHKT 268
Query: 553 KS-----------EVDETYALPATKISRVETHATATPFSKETPSNPVATV 591
+ + ++ T S+ T TP E + TV
Sbjct: 269 TTSFHNSGNSQTKQKSTSFPEKITAASKTTYKTTGTPEESEKTEDSRTTV 318
Score = 30.8 bits (68), Expect = 5.1
Identities = 22/87 (25%), Positives = 37/87 (42%)
Query: 491 TSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMVTQQTIKTESSSTNGAVVKDETSLTTF 550
T + S + T+ + SST SST + +T + SST ++ T+++
Sbjct: 980 TGSESSTASEIITSSTMSVSATASSTASSTASEITMSSAAIPVSSTAYETIRFSTAVSEP 1039
Query: 551 STKSEVDETYALPATKISRVETHATAT 577
T S + L T +S T +T T
Sbjct: 1040 VTASILALESTLAFTTVSNTTTSSTVT 1066
Score = 30.4 bits (67), Expect = 6.7
Identities = 39/179 (21%), Positives = 65/179 (36%), Gaps = 14/179 (7%)
Query: 426 PNSINDTINSTKTEQPATKETSMKNKPDFKALTDSNAILYPSLASNASNHNSHVVDMLRK 485
P++ +T + T T T TS T ++ I S AS +S + K
Sbjct: 1148 PSTAPNTASKTMTTASKTTTTSTITSLPTTVFTTTSKITAGSEIPTASTTDSATTAISTK 1207
Query: 486 NEG----------PHTSANVGVLSSCLDVRTVIPETSVSSTVSSTQTMV----TQQTIKT 531
G P T A S T E + TVSS T V ++ + +
Sbjct: 1208 ASGTTVESAPSTAPPTPAETTTASVPTTTSTTGSENTGHHTVSSVPTTVFATASESSTGS 1267
Query: 532 ESSSTNGAVVKDETSLTTFSTKSEVDETYALPATKISRVETHATATPFSKETPSNPVAT 590
E++ + + + T++TT T + A + +TAT +T + V+T
Sbjct: 1268 ETTRASTSATEVTTAMTTAMTTGSETAVVSTKAPVTTTQSGFSTATVMPAKTTTASVST 1326
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,686,344
Number of Sequences: 37866
Number of extensions: 1611372
Number of successful extensions: 6632
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 48
Number of HSP's successfully gapped in prelim test: 156
Number of HSP's that attempted gapping in prelim test: 4729
Number of HSP's gapped (non-prelim): 1593
length of query: 792
length of database: 18,247,518
effective HSP length: 110
effective length of query: 682
effective length of database: 14,082,258
effective search space: 9604099956
effective search space used: 9604099956
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.