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Search of human proteins with 13899354
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13899354 RNA binding motif protein 4B [Homo sapiens]
(359 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13899354 RNA binding motif protein 4B [Homo sapiens] 728 0.0
gi|93277122 RNA binding motif protein 4 [Homo sapiens] 650 0.0
gi|5454064 RNA binding motif protein 14 [Homo sapiens] 143 3e-34
gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens] 78 1e-14
gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3 ... 72 1e-12
gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1 [... 72 1e-12
gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2 ... 72 1e-12
gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens] 72 1e-12
gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens] 71 2e-12
gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens] 69 5e-12
gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens] 69 5e-12
gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens] 69 5e-12
gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens] 69 5e-12
gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens] 69 5e-12
gi|115511032 ELAV (embryonic lethal, abnormal vision, Drosophila... 69 8e-12
gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens] 69 8e-12
gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 66 6e-11
gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 65 7e-11
gi|188219593 TIA1 protein isoform 1 [Homo sapiens] 65 9e-11
gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens] 65 9e-11
gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens] 65 9e-11
gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Ho... 65 9e-11
gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo... 65 9e-11
gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Ho... 65 9e-11
gi|224028246 non-POU domain containing, octamer-binding isoform ... 65 1e-10
gi|224028244 non-POU domain containing, octamer-binding isoform ... 65 1e-10
gi|34932414 non-POU domain containing, octamer-binding isoform 1... 65 1e-10
gi|71164894 trinucleotide repeat containing 4 [Homo sapiens] 64 2e-10
gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4... 64 2e-10
gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1 ... 64 2e-10
>gi|13899354 RNA binding motif protein 4B [Homo sapiens]
Length = 359
Score = 728 bits (1879), Expect = 0.0
Identities = 359/359 (100%), Positives = 359/359 (100%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
Sbjct: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
Query: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER 120
HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER
Sbjct: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER 120
Query: 121 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT 180
AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT
Sbjct: 121 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT 180
Query: 181 GRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASA 240
GRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASA
Sbjct: 181 GRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALDYYKRYRVRSYEAVAAAAAASA 240
Query: 241 YNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAAATTSSYYG 300
YNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAAATTSSYYG
Sbjct: 241 YNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAAATTSSYYG 300
Query: 301 RDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRARYSAF 359
RDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRARYSAF
Sbjct: 301 RDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRARYSAF 359
>gi|93277122 RNA binding motif protein 4 [Homo sapiens]
Length = 364
Score = 650 bits (1676), Expect = 0.0
Identities = 326/365 (89%), Positives = 340/365 (93%), Gaps = 7/365 (1%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL
Sbjct: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
Query: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMER 120
HGVNINVEASKNKSK STKLHVGNISPTCTN+ELRAKFEEYGPVIECDIVKDYAFVHMER
Sbjct: 61 HGVNINVEASKNKSKTSTKLHVGNISPTCTNKELRAKFEEYGPVIECDIVKDYAFVHMER 120
Query: 121 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRT 180
AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP+DR+
Sbjct: 121 AEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPIDRS 180
Query: 181 GRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGALD-YYKRYR-VRSYEAVAAAAAA 238
GRVAD TEQYNEQYGAVRTPYTM YG+S+YYN+AYGALD YYKR R RSYEAV AAAAA
Sbjct: 181 GRVADLTEQYNEQYGAVRTPYTMSYGDSLYYNNAYGALDAYYKRCRAARSYEAV-AAAAA 239
Query: 239 SAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYDRHLLPNSGAAATSAAMAAAA----AT 294
S YNYAEQT+S LPQVQ+T + SHL STS+DPYDRHLLP SGAAAT+AA AAAA A
Sbjct: 240 SVYNYAEQTLSQLPQVQNTAMASHLTSTSLDPYDRHLLPTSGAAATAAAAAAAAAAVTAA 299
Query: 295 TSSYYGRDRSPLRRAAAMLPTVGEGYGYGPESELSQASAATRNSLYDMARYEREQYVDRA 354
++SYYGRDRSPLRRA A +PTVGEGYGYG ESELSQASAA RNSLYDMARYEREQY DRA
Sbjct: 300 STSYYGRDRSPLRRATAPVPTVGEGYGYGHESELSQASAAARNSLYDMARYEREQYADRA 359
Query: 355 RYSAF 359
RYSAF
Sbjct: 360 RYSAF 364
>gi|5454064 RNA binding motif protein 14 [Homo sapiens]
Length = 669
Score = 143 bits (360), Expect = 3e-34
Identities = 117/361 (32%), Positives = 175/361 (48%), Gaps = 34/361 (9%)
Query: 2 VKLFIGNLP-REATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
+K+F+GN+ + T +E+ +LF YG V+ C ++K + FVH+ + A AI LH ++L
Sbjct: 1 MKIFVGNVDGADTTPEELAALFAPYGTVMSCAVMKQFAFVHMRENAGALRAIEALHGHEL 60
Query: 61 H-GVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHME 119
G + VE S+ + + K+ VGN+S CT+QELR+ FE G VIECD+VKDYAFVHME
Sbjct: 61 RPGRALVVEMSRPRPLNTWKIFVGNVSAACTSQELRSLFERRGRVIECDVVKDYAFVHME 120
Query: 120 RAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECP-VD 178
+ DA AI L+ E +GKR++V+LST + PG+ QSG + K G P
Sbjct: 121 KEADAKAAIAQLNGKEVKGKRINVELSTKGQKKGPGLAVQSG-DKTKKPGAGDTAFPGTG 179
Query: 179 RTGRVADFTEQYNEQYGAV------RTPYTMGYGESMYYND----AYGALDYYKRYRVRS 228
D+ + + G TP G S +Y A + R+
Sbjct: 180 GFSATFDYQQAFGNSTGGFDGQARQPTPPFFGRDRSPLRRSPPRASYVAPLTAQPATYRA 239
Query: 229 YEAVAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVD---PYDRHLL-PNSGAAAT 284
+V+ AA A A + + Q + S+ SV PY L P+S +AA
Sbjct: 240 QPSVSLGAAYRAQPSASLGVGYRTQPMTAQAASYRAQPSVSLGAPYRGQLASPSSQSAAA 299
Query: 285 SA-----AMAAAAATTSSYYGRDRSPLRRAAAMLPTVG------EGYGYGPESELSQASA 333
S+ +A+ SSY G+ AA+ L + G YG P S +QA++
Sbjct: 300 SSLGPYGGAQPSASALSSYGGQ-----AAAASSLNSYGAQGSSLASYGNQPSSYGAQAAS 354
Query: 334 A 334
+
Sbjct: 355 S 355
>gi|148833511 RNA binding motif protein 47 isoform b [Homo sapiens]
Length = 524
Score = 77.8 bits (190), Expect = 1e-14
Identities = 101/373 (27%), Positives = 151/373 (40%), Gaps = 79/373 (21%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLE-----------CDIIKNYGFVHIEDKT--AAE 49
+LFIG +P+ +EI E+ KV E D +KN GF +E ++ AA
Sbjct: 152 RLFIGGIPKMKKREEI---LEEIAKVTEGVLDVIVYASAADKMKNRGFAFVEYESHRAAA 208
Query: 50 DAIRNL---------HHYKLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEE 100
A R L H + ++ ++ + L+V N+ T ++ F +
Sbjct: 209 MARRKLMPGRIQLWGHQIAVDWAEPEIDVDEDVMETVKILYVRNLMIETTEDTIKKSFGQ 268
Query: 101 YGP--VIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGD 158
+ P V ++DYAFVH EDAV A+ L+ TE +G + V L+ P +
Sbjct: 269 FNPGCVERVKKIRDYAFVHFTSREDAVHAMNNLNGTELEGSCLEVTLA------KPVDKE 322
Query: 159 QSGCYRCGKEGHWSKECPVDRTGRVADFTEQYNEQYGAVRTPYTMGYGESMYYNDAYGAL 218
Q Y+ G G A+ +Q + Y PYT+ YY Y AL
Sbjct: 323 QYSRYQKAARG-----------GGAAEAAQQPSYVYSC--DPYTLA-----YYGYPYNAL 364
Query: 219 -----DYYKRYRVRSYEA-VAAAAAASAYNYAEQTMSHLPQVQSTTVTSHLNSTSVDPYD 272
DY+ + + + A + AA A E H TV ++ +V P
Sbjct: 365 IGPNRDYFVKVAIPAIGAQYSMFPAAPAPKMIEDGKIH-------TVEHMISPIAVQPD- 416
Query: 273 RHLLPNSGAAATSAAMAAAAA------TTSSYYGRDRSPLRRAA---AMLPTVG-EGYGY 322
P S AAA +AA AAAAA T + GR +P+ A +PT G G Y
Sbjct: 417 ----PASAAAAAAAAAAAAAAVIPTVSTPPPFQGRPITPVYTVAPNVQRIPTAGIYGASY 472
Query: 323 GPESELSQASAAT 335
P + + A+ AT
Sbjct: 473 VPFAAPATATIAT 485
Score = 40.4 bits (93), Expect = 0.002
Identities = 40/154 (25%), Positives = 68/154 (44%), Gaps = 36/154 (23%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNL 55
++F+G +PR+ E E+ +FE G++ E ++ + Y FV K A+ A+R L
Sbjct: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVREL 131
Query: 56 HHY-----KLHGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIE--CD 108
++Y +L GV +V+ + +L +G I +E+ EE V E D
Sbjct: 132 NNYEIRPGRLLGVCCSVD--------NCRLFIGGIPKMKKREEI---LEEIAKVTEGVLD 180
Query: 109 IV-----------KDYAFVHMERAEDAVEAIRGL 131
++ + +AFV E A A R L
Sbjct: 181 VIVYASAADKMKNRGFAFVEYESHRAAAMARRKL 214
Score = 28.9 bits (63), Expect = 7.5
Identities = 21/70 (30%), Positives = 31/70 (44%), Gaps = 7/70 (10%)
Query: 79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD-------YAFVHMERAEDAVEAIRGL 131
++ VG I EL FE G + E ++ D YAFV +A A+R L
Sbjct: 72 EVFVGKIPRDVYEDELVPVFEAVGRIYELRLMMDFDGKNRGYAFVMYCHKHEAKRAVREL 131
Query: 132 DNTEFQGKRM 141
+N E + R+
Sbjct: 132 NNYEIRPGRL 141
>gi|71164871 CUG triplet repeat, RNA-binding protein 1 isoform 3
[Homo sapiens]
Length = 486
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 16/126 (12%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG----------FVHIEDKTAAEDA 51
+K+F+G +PR +E+++R LFEQYG V E +++++ FV + AA +A
Sbjct: 16 IKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEA 75
Query: 52 IRNLHHYKL-----HGVNIN-VEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVI 105
LH+ K+ H + + ++ KN + KL +G IS CT ++R F +G +
Sbjct: 76 QNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIE 135
Query: 106 ECDIVK 111
EC I++
Sbjct: 136 ECRILR 141
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 49/82 (59%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVL--------ECDIIKNYGFVHIEDKTAAEDAIRNL 55
LFI +LP+E +Q++ +F +G V+ + ++ K +GFV ++ +A+ AI+++
Sbjct: 403 LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSM 462
Query: 56 HHYK--LHGVNINVEASKNKSK 75
+ ++ + + + ++ SKN SK
Sbjct: 463 NGFQIGMKRLKVQLKRSKNDSK 484
Score = 33.5 bits (75), Expect = 0.30
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYA----------FVHMERAEDAVEAI 128
K+ VG + T + ++LR FE+YG V E ++++D + FV + A+EA
Sbjct: 17 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 76
Query: 129 RGLDN 133
L N
Sbjct: 77 NALHN 81
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 8/99 (8%)
Query: 64 NINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAF 115
+I S+ + L + ++ +Q+L F +G V+ + D + F
Sbjct: 387 SIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGF 446
Query: 116 VHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAP 154
V + A AI+ ++ + KR+ VQL S+ + P
Sbjct: 447 VSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKP 485
>gi|5729794 CUG triplet repeat, RNA-binding protein 1 isoform 1
[Homo sapiens]
Length = 482
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 16/126 (12%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG----------FVHIEDKTAAEDA 51
+K+F+G +PR +E+++R LFEQYG V E +++++ FV + AA +A
Sbjct: 16 IKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEA 75
Query: 52 IRNLHHYKL-----HGVNIN-VEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVI 105
LH+ K+ H + + ++ KN + KL +G IS CT ++R F +G +
Sbjct: 76 QNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIE 135
Query: 106 ECDIVK 111
EC I++
Sbjct: 136 ECRILR 141
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 49/82 (59%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVL--------ECDIIKNYGFVHIEDKTAAEDAIRNL 55
LFI +LP+E +Q++ +F +G V+ + ++ K +GFV ++ +A+ AI+++
Sbjct: 399 LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSM 458
Query: 56 HHYK--LHGVNINVEASKNKSK 75
+ ++ + + + ++ SKN SK
Sbjct: 459 NGFQIGMKRLKVQLKRSKNDSK 480
Score = 33.5 bits (75), Expect = 0.30
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYA----------FVHMERAEDAVEAI 128
K+ VG + T + ++LR FE+YG V E ++++D + FV + A+EA
Sbjct: 17 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 76
Query: 129 RGLDN 133
L N
Sbjct: 77 NALHN 81
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 8/99 (8%)
Query: 64 NINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAF 115
+I S+ + L + ++ +Q+L F +G V+ + D + F
Sbjct: 383 SIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGF 442
Query: 116 VHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAP 154
V + A AI+ ++ + KR+ VQL S+ + P
Sbjct: 443 VSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKP 481
>gi|38570081 CUG triplet repeat, RNA-binding protein 1 isoform 2
[Homo sapiens]
Length = 483
Score = 71.6 bits (174), Expect = 1e-12
Identities = 39/126 (30%), Positives = 68/126 (53%), Gaps = 16/126 (12%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG----------FVHIEDKTAAEDA 51
+K+F+G +PR +E+++R LFEQYG V E +++++ FV + AA +A
Sbjct: 16 IKMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEA 75
Query: 52 IRNLHHYKL-----HGVNIN-VEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVI 105
LH+ K+ H + + ++ KN + KL +G IS CT ++R F +G +
Sbjct: 76 QNALHNMKVLPGMHHPIQMKPADSEKNNAVEDRKLFIGMISKKCTENDIRVMFSSFGQIE 135
Query: 106 ECDIVK 111
EC I++
Sbjct: 136 ECRILR 141
Score = 39.7 bits (91), Expect = 0.004
Identities = 22/82 (26%), Positives = 49/82 (59%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVL--------ECDIIKNYGFVHIEDKTAAEDAIRNL 55
LFI +LP+E +Q++ +F +G V+ + ++ K +GFV ++ +A+ AI+++
Sbjct: 400 LFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQSM 459
Query: 56 HHYK--LHGVNINVEASKNKSK 75
+ ++ + + + ++ SKN SK
Sbjct: 460 NGFQIGMKRLKVQLKRSKNDSK 481
Score = 33.5 bits (75), Expect = 0.30
Identities = 20/65 (30%), Positives = 33/65 (50%), Gaps = 10/65 (15%)
Query: 79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYA----------FVHMERAEDAVEAI 128
K+ VG + T + ++LR FE+YG V E ++++D + FV + A+EA
Sbjct: 17 KMFVGQVPRTWSEKDLRELFEQYGAVYEINVLRDRSQNPPQSKGCCFVTFYTRKAALEAQ 76
Query: 129 RGLDN 133
L N
Sbjct: 77 NALHN 81
Score = 30.0 bits (66), Expect = 3.3
Identities = 21/99 (21%), Positives = 41/99 (41%), Gaps = 8/99 (8%)
Query: 64 NINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAF 115
+I S+ + L + ++ +Q+L F +G V+ + D + F
Sbjct: 384 SIGAAGSQKEGPEGANLFIYHLPQEFGDQDLLQMFMPFGNVVSAKVFIDKQTNLSKCFGF 443
Query: 116 VHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAP 154
V + A AI+ ++ + KR+ VQL S+ + P
Sbjct: 444 VSYDNPVSAQAAIQSMNGFQIGMKRLKVQLKRSKNDSKP 482
>gi|46367787 poly(A) binding protein, cytoplasmic 1 [Homo sapiens]
Length = 636
Score = 71.6 bits (174), Expect = 1e-12
Identities = 43/163 (26%), Positives = 78/163 (47%), Gaps = 23/163 (14%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII------KNYGFVHIEDKTAAEDAIRNLHH 57
+FI NL + + + F +G +L C ++ K YGFVH E + AAE AI ++
Sbjct: 101 IFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYGFVHFETQEAAERAIEKMNG 160
Query: 58 YKLHGVNINVEASKN----------KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIEC 107
L+ + V K+ ++K T +++ N ++ L+ F ++GP +
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGARAKEFTNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 108 DIVKD-------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
++ D + FV ER EDA +A+ ++ E GK+++V
Sbjct: 221 KVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
Score = 51.2 bits (121), Expect = 1e-06
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 18/175 (10%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAI 52
M L++G+L + TE + F G +L + ++ Y +V+ + AE A+
Sbjct: 10 MASLYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 53 RNLHHYKLHGVNINVEASKN----KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECD 108
++ + G + + S+ + + + N+ + N+ L F +G ++ C
Sbjct: 70 DTMNFDVIKGKPVRIMWSQRDPSLRKSGVGNIFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 109 IV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMG 157
+V K Y FVH E E A AI ++ +++ V SR +G
Sbjct: 130 VVCDENGSKGYGFVHFETQEAAERAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
Score = 46.6 bits (109), Expect = 3e-05
Identities = 35/176 (19%), Positives = 75/176 (42%), Gaps = 33/176 (18%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNLH 56
++I N + ++ ++ LF ++G L ++ K +GFV E A+ A+ ++
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 57 HYKLHGVNINVEASKNKSKASTK--------------------LHVGNISPTCTNQELRA 96
+L+G I V ++ K + T+ L+V N+ ++ LR
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRK 312
Query: 97 KFEEYGPVIECDIV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLS 146
+F +G + ++ K + FV E+A +A+ ++ K ++V L+
Sbjct: 313 EFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
>gi|45238849 poly(A) binding protein, cytoplasmic 3 [Homo sapiens]
Length = 631
Score = 70.9 bits (172), Expect = 2e-12
Identities = 41/163 (25%), Positives = 78/163 (47%), Gaps = 23/163 (14%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII------KNYGFVHIEDKTAAEDAIRNLHH 57
+F+ NL + + + +G +L C+++ K YGFVH E AAE AI+ ++
Sbjct: 101 IFVKNLDKSINNKALYDTVSAFGNILSCNVVCDENGSKGYGFVHFETHEAAERAIKKMNG 160
Query: 58 YKLHGVNINVEASKNKSKASTKL----------HVGNISPTCTNQELRAKFEEYGPVIEC 107
L+G + V K++ + +L ++ N ++ L+ F ++GP +
Sbjct: 161 MLLNGRKVFVGQFKSRKEREAELGARAKEFPNVYIKNFGEDMDDERLKDLFGKFGPALSV 220
Query: 108 DIVKD-------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
++ D + FV ER EDA +A+ ++ E GK+++V
Sbjct: 221 KVMTDESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYV 263
Score = 53.1 bits (126), Expect = 4e-07
Identities = 39/172 (22%), Positives = 73/172 (42%), Gaps = 18/172 (10%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIK--------NYGFVHIEDKTAAEDAIRNL 55
L++G+L + TE + F G +L I + NY +V+ + AE A+ +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAEHALDTM 72
Query: 56 HHYKLHGVNINVEASKN----KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIV- 110
+ + G + + S+ + + V N+ + N+ L +G ++ C++V
Sbjct: 73 NFDVIKGKPVRIMWSQRDPSLRKSGVGNIFVKNLDKSINNKALYDTVSAFGNILSCNVVC 132
Query: 111 -----KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMG 157
K Y FVH E E A AI+ ++ G+++ V SR +G
Sbjct: 133 DENGSKGYGFVHFETHEAAERAIKKMNGMLLNGRKVFVGQFKSRKEREAELG 184
Score = 45.8 bits (107), Expect = 6e-05
Identities = 35/176 (19%), Positives = 74/176 (42%), Gaps = 33/176 (18%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII-------KNYGFVHIEDKTAAEDAIRNLH 56
++I N + ++ ++ LF ++G L ++ K +GFV E A+ A+ ++
Sbjct: 193 VYIKNFGEDMDDERLKDLFGKFGPALSVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Query: 57 HYKLHGVNINVEASKNKSKASTK--------------------LHVGNISPTCTNQELRA 96
+L+G I V ++ K + T+ L+V N+ ++ LR
Sbjct: 253 GKELNGKQIYVGRAQKKVERQTELKRTFEQMKQDRITRYQVVNLYVKNLDDGIDDERLRK 312
Query: 97 KFEEYGPVIECDIV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLS 146
F +G + ++ K + FV E+A +A+ ++ K ++V L+
Sbjct: 313 AFSPFGTITSAKVMMEGGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYVALA 368
Score = 38.5 bits (88), Expect = 0.009
Identities = 22/81 (27%), Positives = 39/81 (48%), Gaps = 8/81 (9%)
Query: 74 SKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAV 125
S + L+VG++ P T L KF GP++ I +D YA+V+ + +DA
Sbjct: 7 SYPTASLYVGDLHPDVTEAMLYEKFSPAGPILSIRICRDLITSGSSNYAYVNFQHTKDAE 66
Query: 126 EAIRGLDNTEFQGKRMHVQLS 146
A+ ++ +GK + + S
Sbjct: 67 HALDTMNFDVIKGKPVRIMWS 87
>gi|221316765 ELAV-like 4 isoform 1 [Homo sapiens]
Length = 380
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E RSLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 108 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 167
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 168 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ S++
Sbjct: 194 NGQKPSGATEPITVKFANNPSQKSSQ 219
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 76 ASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEA 127
+ T L V + T +E R+ F G + C +V+D Y FV+ +DA +A
Sbjct: 44 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103
Query: 128 IRGLDNTEFQGKRMHV 143
I L+ Q K + V
Sbjct: 104 INTLNGLRLQTKTIKV 119
Score = 32.3 bits (72), Expect = 0.67
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL ++ E + LF +G V +I K +GFV + + A AI +L
Sbjct: 299 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 358
Query: 56 HHYKLHGVNINVEASKNKSKAS 77
+ Y+L + V NK+ S
Sbjct: 359 NGYRLGDRVLQVSFKTNKAHKS 380
>gi|221316773 ELAV-like 4 isoform 5 [Homo sapiens]
Length = 369
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E RSLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 51 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 110
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 111 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 170
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 171 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 203
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 137 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 196
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ S++
Sbjct: 197 NGQKPSGATEPITVKFANNPSQKSSQ 222
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 76 ASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEA 127
+ T L V + T +E R+ F G + C +V+D Y FV+ +DA +A
Sbjct: 47 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 106
Query: 128 IRGLDNTEFQGKRMHV 143
I L+ Q K + V
Sbjct: 107 INTLNGLRLQTKTIKV 122
Score = 32.3 bits (72), Expect = 0.67
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL ++ E + LF +G V +I K +GFV + + A AI +L
Sbjct: 288 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 347
Query: 56 HHYKLHGVNINVEASKNKSKAS 77
+ Y+L + V NK+ S
Sbjct: 348 NGYRLGDRVLQVSFKTNKAHKS 369
>gi|221316771 ELAV-like 4 isoform 4 [Homo sapiens]
Length = 366
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E RSLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 108 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 167
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 168 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ S++
Sbjct: 194 NGQKPSGATEPITVKFANNPSQKSSQ 219
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 76 ASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEA 127
+ T L V + T +E R+ F G + C +V+D Y FV+ +DA +A
Sbjct: 44 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103
Query: 128 IRGLDNTEFQGKRMHV 143
I L+ Q K + V
Sbjct: 104 INTLNGLRLQTKTIKV 119
Score = 32.3 bits (72), Expect = 0.67
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL ++ E + LF +G V +I K +GFV + + A AI +L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 56 HHYKLHGVNINVEASKNKSKAS 77
+ Y+L + V NK+ S
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHKS 366
>gi|221316769 ELAV-like 4 isoform 3 [Homo sapiens]
Length = 383
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E RSLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 65 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 124
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 125 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 184
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 185 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 217
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 151 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 210
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ S++
Sbjct: 211 NGQKPSGATEPITVKFANNPSQKSSQ 236
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 76 ASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEA 127
+ T L V + T +E R+ F G + C +V+D Y FV+ +DA +A
Sbjct: 61 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 120
Query: 128 IRGLDNTEFQGKRMHV 143
I L+ Q K + V
Sbjct: 121 INTLNGLRLQTKTIKV 136
Score = 32.3 bits (72), Expect = 0.67
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL ++ E + LF +G V +I K +GFV + + A AI +L
Sbjct: 302 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 361
Query: 56 HHYKLHGVNINVEASKNKSKAS 77
+ Y+L + V NK+ S
Sbjct: 362 NGYRLGDRVLQVSFKTNKAHKS 383
>gi|221316767 ELAV-like 4 isoform 2 [Homo sapiens]
Length = 366
Score = 69.3 bits (168), Expect = 5e-12
Identities = 45/153 (29%), Positives = 74/153 (48%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E RSLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 48 LIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 107
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 108 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 167
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 168 VTGVSRGVGFIRFDKRIEAEEAIKGLNGQKPSG 200
Score = 47.4 bits (111), Expect = 2e-05
Identities = 25/86 (29%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 134 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 193
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ S++
Sbjct: 194 NGQKPSGATEPITVKFANNPSQKSSQ 219
Score = 34.3 bits (77), Expect = 0.18
Identities = 22/76 (28%), Positives = 34/76 (44%), Gaps = 8/76 (10%)
Query: 76 ASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEA 127
+ T L V + T +E R+ F G + C +V+D Y FV+ +DA +A
Sbjct: 44 SKTNLIVNYLPQNMTQEEFRSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKA 103
Query: 128 IRGLDNTEFQGKRMHV 143
I L+ Q K + V
Sbjct: 104 INTLNGLRLQTKTIKV 119
Score = 32.3 bits (72), Expect = 0.67
Identities = 23/82 (28%), Positives = 38/82 (46%), Gaps = 8/82 (9%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL ++ E + LF +G V +I K +GFV + + A AI +L
Sbjct: 285 IFVYNLSPDSDESVLWQLFGPFGAVNNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 344
Query: 56 HHYKLHGVNINVEASKNKSKAS 77
+ Y+L + V NK+ S
Sbjct: 345 NGYRLGDRVLQVSFKTNKAHKS 366
>gi|115511032 ELAV (embryonic lethal, abnormal vision,
Drosophila)-like 2 (Hu antigen B) [Homo sapiens]
Length = 359
Score = 68.6 bits (166), Expect = 8e-12
Identities = 44/153 (28%), Positives = 75/153 (49%), Gaps = 18/153 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T++E++SLF G++ C ++++ YGFV+ D AE AI L
Sbjct: 41 LIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDPKDAEKAINTL 100
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ +L I V ++ S + L+V + T T +EL F +YG +I I+ D
Sbjct: 101 NGLRLQTKTIKVSYARPSSASIRDANLYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQ 160
Query: 113 -------YAFVHMERAEDAVEAIRGLDNTEFQG 138
F+ ++ +A EAI+GL+ + G
Sbjct: 161 VTGISRGVGFIRFDKRIEAEEAIKGLNGQKPPG 193
Score = 45.4 bits (106), Expect = 8e-05
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 10/86 (11%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ T++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 127 LYVSGLPKTMTQKELEQLFSQYGRIITSRILVDQVTGISRGVGFIRFDKRIEAEEAIKGL 186
Query: 56 HHYKLHGVN--INVEASKNKSKASTK 79
+ K G I V+ + N S+ + +
Sbjct: 187 NGQKPPGATEPITVKFANNPSQKTNQ 212
Score = 37.0 bits (84), Expect = 0.027
Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 8/82 (9%)
Query: 70 SKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERA 121
S N + T L V + T +EL++ F G + C +V+D Y FV+
Sbjct: 31 SGNTEDSKTNLIVNYLPQNMTQEELKSLFGSIGEIESCKLVRDKITGQSLGYGFVNYIDP 90
Query: 122 EDAVEAIRGLDNTEFQGKRMHV 143
+DA +AI L+ Q K + V
Sbjct: 91 KDAEKAINTLNGLRLQTKTIKV 112
Score = 32.3 bits (72), Expect = 0.67
Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 8/79 (10%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL +A E + +F +G V +I K +GFV + + A AI +L
Sbjct: 278 IFVYNLAPDADESILWQMFGPFGAVTNVKVIRDFNTNKCKGFGFVTMTNYDEAAMAIASL 337
Query: 56 HHYKLHGVNINVEASKNKS 74
+ Y+L + V NK+
Sbjct: 338 NGYRLGDRVLQVSFKTNKT 356
>gi|4506903 splicing factor, arginine/serine-rich 9 [Homo sapiens]
Length = 221
Score = 68.6 bits (166), Expect = 8e-12
Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 27/201 (13%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG-----FVHIEDKTAAEDAIRNLHH 57
++++GNLP + E+++ LF +YG++ E ++ +G FV ED AEDAI +
Sbjct: 15 RIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRDAEDAIYGRNG 74
Query: 58 YKLHGVNINVEASKN----------------KSKASTKLHVGNISPTCTNQELRAKFEEY 101
Y + VE + ++ ++ V + P+ + Q+L+ E
Sbjct: 75 YDYGQCRLRVEFPRTYGGRGGWPRGGRNGPPTRRSDFRVLVSGLPPSGSWQDLKDHMREA 134
Query: 102 GPVIECDIVKD-YAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQS 160
G V D+ KD V R ED A+R LD+T+F R H + TS +R P
Sbjct: 135 GDVCYADVQKDGVGMVEYLRKEDMEYALRKLDDTKF---RSH-EGETSYIRVYPERSTSY 190
Query: 161 GCYRCGKEGHWSKECPVDRTG 181
G Y + G ++ P G
Sbjct: 191 G-YSRSRSGSRGRDSPYQSRG 210
Score = 36.6 bits (83), Expect = 0.036
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 12/106 (11%)
Query: 69 ASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDI-----VKDYAFVHMERAED 123
A + + +++VGN+ ++L F +YG + E ++ + +AFV E D
Sbjct: 5 ADERGGEGDGRIYVGNLPTDVREKDLEDLFYKYGRIREIELKNRHGLVPFAFVRFEDPRD 64
Query: 124 AVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMGDQSGCYRCGKEG 169
A +AI G + ++ R+ V+ RT G G G R G+ G
Sbjct: 65 AEDAIYGRNGYDYGQCRLRVEFP----RTYGGRG---GWPRGGRNG 103
>gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens]
Length = 238
Score = 65.9 bits (159), Expect = 6e-11
Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 11/109 (10%)
Query: 78 TKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD---YAFVHMERAEDAVEAIRGLDNT 134
TK++VGN+ EL F YGP+ I ++ +AFV E DA +A+RGLD
Sbjct: 11 TKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGK 70
Query: 135 EFQGKRMHVQLST-----SRLRTAPG---MGDQSGCYRCGKEGHWSKEC 175
G R+ V+LST SR P CY CG++GH++ +C
Sbjct: 71 VICGSRVRVELSTGMPRRSRFDRPPARRPFDPNDRCYECGEKGHYAYDC 119
Score = 43.1 bits (100), Expect = 4e-04
Identities = 26/78 (33%), Positives = 38/78 (48%), Gaps = 3/78 (3%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN---YGFVHIEDKTAAEDAIRNLHHYK 59
K+++GNL A + E+ F YG + I +N + FV ED AEDA+R L
Sbjct: 12 KVYVGNLGTGAGKGELERAFSYYGPLRTVWIARNPPGFAFVEFEDPRDAEDAVRGLDGKV 71
Query: 60 LHGVNINVEASKNKSKAS 77
+ G + VE S + S
Sbjct: 72 ICGSRVRVELSTGMPRRS 89
>gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens]
Length = 494
Score = 65.5 bits (158), Expect = 7e-11
Identities = 44/172 (25%), Positives = 76/172 (44%), Gaps = 29/172 (16%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYGFVHIEDKTAAEDAIRNLHHYKL 60
M +++IG L +A E+++ F+ YGK+LE D+ YGFV +D A+DA+ L+ L
Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDL 60
Query: 61 HGVNINVEASKN--------------------------KSKASTKLHVGNISPTCTNQEL 94
G + VE ++ ++ +L V N+S C+ Q+L
Sbjct: 61 CGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLSSRCSWQDL 120
Query: 95 RAKFEEYGPVIECDI---VKDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
+ + G V D K+ + D A+ LD TE G+++ +
Sbjct: 121 KDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRL 172
Score = 43.5 bits (101), Expect = 3e-04
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 8/103 (7%)
Query: 79 KLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAEDAVEAIRGLDNTEFQG 138
++++G +S +++ F+ YG ++E D+ Y FV + DA +A+ L+ + G
Sbjct: 3 RVYIGRLSYQARERDVERFFKGYGKILEVDLKNGYGFVEFDDLRDADDAVYELNGKDLCG 62
Query: 139 KRMHVQLSTSRLRTAPGMGDQSGCYRCGKEGHWSKECPVDRTG 181
+R+ V+ + R G Y G+ G+ + D+ G
Sbjct: 63 ERVIVEHARGPRR--------DGSYGSGRSGYGYRRSGRDKYG 97
>gi|188219593 TIA1 protein isoform 1 [Homo sapiens]
Length = 375
Score = 65.1 bits (157), Expect = 9e-11
Identities = 46/166 (27%), Positives = 76/166 (45%), Gaps = 20/166 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN------YGFVHIEDKTAAEDAIRNLHH 57
L++GNL R+ TE I LF Q G C +I + Y FV + A A+ ++
Sbjct: 9 LYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNG 68
Query: 58 YKLHG--VNINVEASKNKSKASTKLH----VGNISPTCTNQELRAKFEEYGPVIECDIVK 111
K+ G V +N + + K T H VG++SP T ++++A F +G + + +VK
Sbjct: 69 RKIMGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVK 128
Query: 112 D--------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSR 149
D Y FV DA AI+ + G+++ +T +
Sbjct: 129 DMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRK 174
Score = 57.4 bits (137), Expect = 2e-08
Identities = 42/169 (24%), Positives = 77/169 (45%), Gaps = 34/169 (20%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
+F+G+L E T ++I++ F +G++ + ++K+ YGFV +K AE+AI+ +
Sbjct: 97 VFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQM 156
Query: 56 HHYKLHGVNINVE-------ASKNKSKASTK-----------------LHVGNISPTCTN 91
L G I A K+ +++TK ++ G ++ T
Sbjct: 157 GGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTE 216
Query: 92 QELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTEFQG 138
Q +R F +G ++E + D Y+FV E A AI ++ T +G
Sbjct: 217 QLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEG 265
>gi|49355761 ELAV-like protein 3 isoform 1 [Homo sapiens]
Length = 367
Score = 65.1 bits (157), Expect = 9e-11
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 18/147 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T+ E +SLF G + C ++++ YGFV+ D A+ AI L
Sbjct: 41 LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ KL I V ++ S + L+V + T + +E+ F +YG +I I+ D
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQ 160
Query: 113 -------YAFVHMERAEDAVEAIRGLD 132
F+ ++ +A EAI+GL+
Sbjct: 161 VTGVSRGVGFIRFDKRIEAEEAIKGLN 187
Score = 42.0 bits (97), Expect = 9e-04
Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ +++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 56 HHYKLHGV--NINVEASKNKSK 75
+ K G I V+ + N S+
Sbjct: 187 NGQKPLGAAEPITVKFANNPSQ 208
Score = 32.3 bits (72), Expect = 0.67
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 8/65 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL EA E + LF +G V +I K +GFV + + A AI +L
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 56 HHYKL 60
+ Y+L
Sbjct: 346 NGYRL 350
Score = 29.3 bits (64), Expect = 5.7
Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 80 LHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEAIRGL 131
+ V N+SP L F +G V +++D + FV M ++A AI L
Sbjct: 286 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 345
Query: 132 DNTEFQGKRMHVQLSTSRLRTA 153
+ + + V TS+ A
Sbjct: 346 NGYRLGERVLQVSFKTSKQHKA 367
>gi|49355765 ELAV-like protein 3 isoform 2 [Homo sapiens]
Length = 360
Score = 65.1 bits (157), Expect = 9e-11
Identities = 41/147 (27%), Positives = 70/147 (47%), Gaps = 18/147 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIRNL 55
L + LP+ T+ E +SLF G + C ++++ YGFV+ D A+ AI L
Sbjct: 41 LIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTL 100
Query: 56 HHYKLHGVNINVEASKNKSKA--STKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD- 112
+ KL I V ++ S + L+V + T + +E+ F +YG +I I+ D
Sbjct: 101 NGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQ 160
Query: 113 -------YAFVHMERAEDAVEAIRGLD 132
F+ ++ +A EAI+GL+
Sbjct: 161 VTGVSRGVGFIRFDKRIEAEEAIKGLN 187
Score = 42.0 bits (97), Expect = 9e-04
Identities = 23/82 (28%), Positives = 44/82 (53%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
L++ LP+ +++E+ LF QYG+++ I+ + GF+ + + AE+AI+ L
Sbjct: 127 LYVSGLPKTMSQKEMEQLFSQYGRIITSRILVDQVTGVSRGVGFIRFDKRIEAEEAIKGL 186
Query: 56 HHYKLHGV--NINVEASKNKSK 75
+ K G I V+ + N S+
Sbjct: 187 NGQKPLGAAEPITVKFANNPSQ 208
Score = 32.3 bits (72), Expect = 0.67
Identities = 21/65 (32%), Positives = 32/65 (49%), Gaps = 8/65 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+F+ NL EA E + LF +G V +I K +GFV + + A AI +L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 56 HHYKL 60
+ Y+L
Sbjct: 339 NGYRL 343
Score = 29.3 bits (64), Expect = 5.7
Identities = 20/82 (24%), Positives = 33/82 (40%), Gaps = 8/82 (9%)
Query: 80 LHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--------YAFVHMERAEDAVEAIRGL 131
+ V N+SP L F +G V +++D + FV M ++A AI L
Sbjct: 279 IFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASL 338
Query: 132 DNTEFQGKRMHVQLSTSRLRTA 153
+ + + V TS+ A
Sbjct: 339 NGYRLGERVLQVSFKTSKQHKA 360
>gi|208431836 poly A binding protein, cytoplasmic 4 isoform 3 [Homo
sapiens]
Length = 631
Score = 65.1 bits (157), Expect = 9e-11
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 23/163 (14%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII------KNYGFVHIEDKTAAEDAIRNLHH 57
+FI NL + + + F +G +L C ++ K Y FVH E + AA+ AI ++
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 58 YKLHGVNINVEASKN----------KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIEC 107
L+ + V K+ K+K T +++ N ++ L+ F ++G +
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 108 DIVKD-------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
+++D + FV E+ EDA +A+ ++ E GK + V
Sbjct: 221 KVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 18/175 (10%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAI 52
M L++G+L + TE + F G VL + ++ Y +V+ + AE A+
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 53 RNLHHYKLHGVNINVEASKN----KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECD 108
++ + G I + S+ + + + N+ + N+ L F +G ++ C
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 109 IV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMG 157
+V K YAFVH E E A +AI ++ +++ V SR +G
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
>gi|4504715 poly A binding protein, cytoplasmic 4 isoform 2 [Homo
sapiens]
Length = 644
Score = 65.1 bits (157), Expect = 9e-11
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 23/163 (14%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII------KNYGFVHIEDKTAAEDAIRNLHH 57
+FI NL + + + F +G +L C ++ K Y FVH E + AA+ AI ++
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 58 YKLHGVNINVEASKN----------KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIEC 107
L+ + V K+ K+K T +++ N ++ L+ F ++G +
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 108 DIVKD-------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
+++D + FV E+ EDA +A+ ++ E GK + V
Sbjct: 221 KVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 18/175 (10%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAI 52
M L++G+L + TE + F G VL + ++ Y +V+ + AE A+
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 53 RNLHHYKLHGVNINVEASKN----KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECD 108
++ + G I + S+ + + + N+ + N+ L F +G ++ C
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 109 IV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMG 157
+V K YAFVH E E A +AI ++ +++ V SR +G
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
>gi|208431833 poly A binding protein, cytoplasmic 4 isoform 1 [Homo
sapiens]
Length = 660
Score = 65.1 bits (157), Expect = 9e-11
Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 23/163 (14%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII------KNYGFVHIEDKTAAEDAIRNLHH 57
+FI NL + + + F +G +L C ++ K Y FVH E + AA+ AI ++
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENGSKGYAFVHFETQEAADKAIEKMNG 160
Query: 58 YKLHGVNINVEASKN----------KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIEC 107
L+ + V K+ K+K T +++ N ++ L+ F ++G +
Sbjct: 161 MLLNDRKVFVGRFKSRKEREAELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSV 220
Query: 108 DIVKD-------YAFVHMERAEDAVEAIRGLDNTEFQGKRMHV 143
+++D + FV E+ EDA +A+ ++ E GK + V
Sbjct: 221 KVMRDPNGKSKGFGFVSYEKHEDANKAVEEMNGKEISGKIIFV 263
Score = 53.5 bits (127), Expect = 3e-07
Identities = 40/175 (22%), Positives = 74/175 (42%), Gaps = 18/175 (10%)
Query: 1 MVKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAI 52
M L++G+L + TE + F G VL + ++ Y +V+ + AE A+
Sbjct: 10 MASLYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERAL 69
Query: 53 RNLHHYKLHGVNINVEASKN----KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECD 108
++ + G I + S+ + + + N+ + N+ L F +G ++ C
Sbjct: 70 DTMNFDVIKGKPIRIMWSQRDPSLRKSGVGNVFIKNLDKSIDNKALYDTFSAFGNILSCK 129
Query: 109 IV------KDYAFVHMERAEDAVEAIRGLDNTEFQGKRMHVQLSTSRLRTAPGMG 157
+V K YAFVH E E A +AI ++ +++ V SR +G
Sbjct: 130 VVCDENGSKGYAFVHFETQEAADKAIEKMNGMLLNDRKVFVGRFKSRKEREAELG 184
>gi|224028246 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 64.7 bits (156), Expect = 1e-10
Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 6/112 (5%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--YGFVHIEDKTAAEDAIRNLHHYKL 60
+LF+GNLP + TE+E+R LFE+YGK E I K+ +GF+ +E +T AE A L + L
Sbjct: 75 RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPL 134
Query: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD 112
G + V + + S L V N+ +N+ L F +G V ++ D
Sbjct: 135 RGKQLRVRFACH----SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVD 182
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 78 TKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTE 135
++L VGN+ P T +E+R FE+YG E I KD + F+ +E A A LDN
Sbjct: 74 SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMP 133
Query: 136 FQGKRMHVQLS 146
+GK++ V+ +
Sbjct: 134 LRGKQLRVRFA 144
>gi|224028244 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 64.7 bits (156), Expect = 1e-10
Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 6/112 (5%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--YGFVHIEDKTAAEDAIRNLHHYKL 60
+LF+GNLP + TE+E+R LFE+YGK E I K+ +GF+ +E +T AE A L + L
Sbjct: 75 RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPL 134
Query: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD 112
G + V + + S L V N+ +N+ L F +G V ++ D
Sbjct: 135 RGKQLRVRFACH----SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVD 182
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 78 TKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTE 135
++L VGN+ P T +E+R FE+YG E I KD + F+ +E A A LDN
Sbjct: 74 SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMP 133
Query: 136 FQGKRMHVQLS 146
+GK++ V+ +
Sbjct: 134 LRGKQLRVRFA 144
>gi|34932414 non-POU domain containing, octamer-binding isoform 1
[Homo sapiens]
Length = 471
Score = 64.7 bits (156), Expect = 1e-10
Identities = 40/112 (35%), Positives = 61/112 (54%), Gaps = 6/112 (5%)
Query: 3 KLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--YGFVHIEDKTAAEDAIRNLHHYKL 60
+LF+GNLP + TE+E+R LFE+YGK E I K+ +GF+ +E +T AE A L + L
Sbjct: 75 RLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMPL 134
Query: 61 HGVNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD 112
G + V + + S L V N+ +N+ L F +G V ++ D
Sbjct: 135 RGKQLRVRFACH----SASLTVRNLPQYVSNELLEEAFSVFGQVERAVVIVD 182
Score = 45.4 bits (106), Expect = 8e-05
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 2/71 (2%)
Query: 78 TKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD--YAFVHMERAEDAVEAIRGLDNTE 135
++L VGN+ P T +E+R FE+YG E I KD + F+ +E A A LDN
Sbjct: 74 SRLFVGNLPPDITEEEMRKLFEKYGKAGEVFIHKDKGFGFIRLETRTLAEIAKVELDNMP 133
Query: 136 FQGKRMHVQLS 146
+GK++ V+ +
Sbjct: 134 LRGKQLRVRFA 144
>gi|71164894 trinucleotide repeat containing 4 [Homo sapiens]
Length = 465
Score = 64.3 bits (155), Expect = 2e-10
Identities = 45/152 (29%), Positives = 80/152 (52%), Gaps = 19/152 (12%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKN--------YGFVHIEDKTAAEDAIR 53
+KLF+G +PR E++++ +FEQ+G++ E +IK+ F+ + +A A
Sbjct: 7 IKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLHKGCAFLTYCARDSALKAQS 66
Query: 54 NLHHYK-LHGVN--INVEASKNKSKA-STKLHVGNISPTCTNQELRAKFEEYGPVIECDI 109
LH K L G+N I V+ + ++S+ KL VG + T++++R FE +G + EC +
Sbjct: 67 ALHEQKTLPGMNRPIQVKPADSESRGEDRKLFVGMLGKQQTDEDVRKMFEPFGTIDECTV 126
Query: 110 V-------KDYAFVHMERAEDAVEAIRGLDNT 134
+ K AFV + +A AI L ++
Sbjct: 127 LRGPDGTSKGCAFVKFQTHAEAQAAINTLHSS 158
Score = 38.1 bits (87), Expect = 0.012
Identities = 20/78 (25%), Positives = 42/78 (53%), Gaps = 8/78 (10%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVLECDII--------KNYGFVHIEDKTAAEDAIRNL 55
+FI +LP+E T+ EI +F +G V+ + K +GFV ++ +A+ AI+ +
Sbjct: 382 IFIYHLPQEFTDSEILQMFVPFGHVISAKVFVDRATNQSKCFGFVSFDNPASAQAAIQAM 441
Query: 56 HHYKLHGVNINVEASKNK 73
+ +++ + V+ + K
Sbjct: 442 NGFQIGMKRLKVQLKRPK 459
Score = 30.0 bits (66), Expect = 3.3
Identities = 15/46 (32%), Positives = 25/46 (54%), Gaps = 1/46 (2%)
Query: 73 KSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKD-YAFVH 117
K + KL VG I ++L+ FE++G + E ++KD Y +H
Sbjct: 2 KEPDAIKLFVGQIPRHLEEKDLKPIFEQFGRIFELTVIKDKYTGLH 47
>gi|134152719 CUG triplet repeat, RNA binding protein 2 isoform 4
[Homo sapiens]
Length = 488
Score = 63.9 bits (154), Expect = 2e-10
Identities = 40/157 (25%), Positives = 75/157 (47%), Gaps = 23/157 (14%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG----------FVHIEDKTAAEDA 51
+K+F+G +PR +E+E++ LFE YG V + +++++ FV + AA +A
Sbjct: 16 IKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEA 75
Query: 52 IRNLHHYKL-----HGVNIN-VEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVI 105
LH+ K H + + ++ K+ + KL +G +S C ++R F +G +
Sbjct: 76 QNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIE 135
Query: 106 ECDIV-------KDYAFVHMERAEDAVEAIRGLDNTE 135
EC I+ + AFV A AI+ + ++
Sbjct: 136 ECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQ 172
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVL--------ECDIIKNYGFVHIEDKTAAEDAIRNL 55
LFI +LP+E +Q+I +F +G V+ + ++ K +GFV ++ +A+ AI+ +
Sbjct: 405 LFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAM 464
Query: 56 HHYK--LHGVNINVEASKNKSK 75
+ ++ + + + ++ SKN SK
Sbjct: 465 NGFQIGMKRLKVQLKRSKNDSK 486
Score = 30.8 bits (68), Expect = 2.0
Identities = 22/96 (22%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 63 VNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAE 122
+N ++ S + K+ VG I + + +EL+ FE YG V + ++++D R++
Sbjct: 1 MNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRD-------RSQ 53
Query: 123 DAVEAIRGLDNTEFQGKR--MHVQLSTSRLRTAPGM 156
+ ++ +G F ++ + Q + ++T PGM
Sbjct: 54 NPPQS-KGCCFVTFYTRKAALEAQNALHNIKTLPGM 88
>gi|68303645 CUG triplet repeat, RNA binding protein 2 isoform 1
[Homo sapiens]
Length = 490
Score = 63.9 bits (154), Expect = 2e-10
Identities = 40/157 (25%), Positives = 75/157 (47%), Gaps = 23/157 (14%)
Query: 2 VKLFIGNLPREATEQEIRSLFEQYGKVLECDIIKNYG----------FVHIEDKTAAEDA 51
+K+F+G +PR +E+E++ LFE YG V + +++++ FV + AA +A
Sbjct: 16 IKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAALEA 75
Query: 52 IRNLHHYKL-----HGVNIN-VEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVI 105
LH+ K H + + ++ K+ + KL +G +S C ++R F +G +
Sbjct: 76 QNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIE 135
Query: 106 ECDIV-------KDYAFVHMERAEDAVEAIRGLDNTE 135
EC I+ + AFV A AI+ + ++
Sbjct: 136 ECRILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQ 172
Score = 39.7 bits (91), Expect = 0.004
Identities = 23/82 (28%), Positives = 48/82 (58%), Gaps = 10/82 (12%)
Query: 4 LFIGNLPREATEQEIRSLFEQYGKVL--------ECDIIKNYGFVHIEDKTAAEDAIRNL 55
LFI +LP+E +Q+I +F +G V+ + ++ K +GFV ++ +A+ AI+ +
Sbjct: 407 LFIYHLPQEFGDQDILQMFMPFGNVISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAM 466
Query: 56 HHYK--LHGVNINVEASKNKSK 75
+ ++ + + + ++ SKN SK
Sbjct: 467 NGFQIGMKRLKVQLKRSKNDSK 488
Score = 30.8 bits (68), Expect = 2.0
Identities = 22/96 (22%), Positives = 48/96 (50%), Gaps = 10/96 (10%)
Query: 63 VNINVEASKNKSKASTKLHVGNISPTCTNQELRAKFEEYGPVIECDIVKDYAFVHMERAE 122
+N ++ S + K+ VG I + + +EL+ FE YG V + ++++D R++
Sbjct: 1 MNGALDHSDQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRD-------RSQ 53
Query: 123 DAVEAIRGLDNTEFQGKR--MHVQLSTSRLRTAPGM 156
+ ++ +G F ++ + Q + ++T PGM
Sbjct: 54 NPPQS-KGCCFVTFYTRKAALEAQNALHNIKTLPGM 88
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.129 0.374
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,564,525
Number of Sequences: 37866
Number of extensions: 514967
Number of successful extensions: 3250
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 242
Number of HSP's successfully gapped in prelim test: 97
Number of HSP's that attempted gapping in prelim test: 2207
Number of HSP's gapped (non-prelim): 827
length of query: 359
length of database: 18,247,518
effective HSP length: 103
effective length of query: 256
effective length of database: 14,347,320
effective search space: 3672913920
effective search space used: 3672913920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.