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Search of human proteins with 136255216
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|136255216 proline-rich transmembrane protein 3 [Homo
sapiens]
(981 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens] 1998 0.0
gi|168229226 hypothetical protein LOC401399 [Homo sapiens] 140 6e-33
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 79 2e-14
gi|163965366 nascent polypeptide-associated complex alpha subuni... 72 2e-12
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 70 1e-11
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens] 67 6e-11
gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens] 67 8e-11
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin... 65 2e-10
gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens] 65 4e-10
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 65 4e-10
gi|110349719 titin isoform N2-A [Homo sapiens] 63 2e-09
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 63 2e-09
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 63 2e-09
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 62 2e-09
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 62 3e-09
gi|38373671 SEC24-related protein C [Homo sapiens] 61 4e-09
gi|38373669 SEC24-related protein C [Homo sapiens] 61 4e-09
gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sap... 61 4e-09
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 60 1e-08
gi|54860079 nadrin isoform 1 [Homo sapiens] 60 1e-08
gi|110832843 TBP-associated factor 4 [Homo sapiens] 59 2e-08
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 59 2e-08
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 59 3e-08
gi|40353727 synaptopodin isoform A [Homo sapiens] 59 3e-08
gi|41281612 zinc finger protein 828 [Homo sapiens] 59 3e-08
gi|150170670 piccolo isoform 2 [Homo sapiens] 59 3e-08
gi|150378539 piccolo isoform 1 [Homo sapiens] 59 3e-08
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 59 3e-08
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 59 3e-08
gi|112382226 atrophin-1 like protein isoform b [Homo sapiens] 59 3e-08
>gi|136255216 proline-rich transmembrane protein 3 [Homo sapiens]
Length = 981
Score = 1998 bits (5176), Expect = 0.0
Identities = 981/981 (100%), Positives = 981/981 (100%)
Query: 1 MASSPWGCVCGLLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDV 60
MASSPWGCVCGLLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDV
Sbjct: 1 MASSPWGCVCGLLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDV 60
Query: 61 FPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQ 120
FPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQ
Sbjct: 61 FPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQ 120
Query: 121 GPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQ 180
GPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQ
Sbjct: 121 GPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQ 180
Query: 181 WPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGP 240
WPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGP
Sbjct: 181 WPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGP 240
Query: 241 HFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEV 300
HFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEV
Sbjct: 241 HFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEV 300
Query: 301 SSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEA 360
SSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEA
Sbjct: 301 SSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEA 360
Query: 361 PGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLI 420
PGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLI
Sbjct: 361 PGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLI 420
Query: 421 RVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGV 480
RVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGV
Sbjct: 421 RVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLRRVLSFSWELHVYGVGV 480
Query: 481 LFLLPALLALAALAAAPAGPRLALVAAVLVLVASALRSAYMLTDPYGSQARLGVRGGLVL 540
LFLLPALLALAALAAAPAGPRLALVAAVLVLVASALRSAYMLTDPYGSQARLGVRGGLVL
Sbjct: 481 LFLLPALLALAALAAAPAGPRLALVAAVLVLVASALRSAYMLTDPYGSQARLGVRGGLVL 540
Query: 541 YNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLSTWSVLNLL 600
YNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLSTWSVLNLL
Sbjct: 541 YNLPFPLLLTALAALTLLGLGAGLPPPLQNPLLLGAVALVHGVGLLATDLLSTWSVLNLL 600
Query: 601 TQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAGALGLLASGLQLAAALW 660
TQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAGALGLLASGLQLAAALW
Sbjct: 601 TQGLSCAWGAAVALGTLCLCRRRLLDGPRGWDASPGPRLLAVAGALGLLASGLQLAAALW 660
Query: 661 LYPGPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRLAC 720
LYPGPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRLAC
Sbjct: 661 LYPGPGRVGRFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRLAC 720
Query: 721 PAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGR 780
PAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGR
Sbjct: 721 PAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGR 780
Query: 781 GPQGGPGLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRGLA 840
GPQGGPGLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRGLA
Sbjct: 781 GPQGGPGLSRNGVGPAPSLSELDLRPPSPINLSRSIDAALFREHLVRDSVFQRCGLRGLA 840
Query: 841 SPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRVRGPVPQHVVEAPDGAAAAAS 900
SPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRVRGPVPQHVVEAPDGAAAAAS
Sbjct: 841 SPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRVRGPVPQHVVEAPDGAAAAAS 900
Query: 901 GSSLDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPAPTPAPDSTAARQGDGQG 960
GSSLDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPAPTPAPDSTAARQGDGQG
Sbjct: 901 GSSLDSFSRGSLKISWNPWRHGLSSVDSLPLDELPSTVQLLPAPTPAPDSTAARQGDGQG 960
Query: 961 EVQPRGKPGESRSASSDTIEL 981
EVQPRGKPGESRSASSDTIEL
Sbjct: 961 EVQPRGKPGESRSASSDTIEL 981
>gi|168229226 hypothetical protein LOC401399 [Homo sapiens]
Length = 899
Score = 140 bits (353), Expect = 6e-33
Identities = 174/543 (32%), Positives = 217/543 (39%), Gaps = 97/543 (17%)
Query: 405 PAPPVQAPSTSRRGLIRVTTQRALGQP---PPPEPTASSMASAPA-SSPPANATAP---- 456
P P+ P ++ +LG P P P + S+ P P A P
Sbjct: 294 PTVPISGPDD-------LSPPASLGNPSGQPECGPGSCSVGELPEREGQPPEAPRPLFFL 346
Query: 457 --PLRWGPLRRVLSFSWELHVYGVGVLFLLPALLALAALA-----AAPAGPRLALVAAVL 509
W R +WE HVYGVG LF L ALLAL ALA P P LAL+ +L
Sbjct: 347 TLEADWAEARARWGLAWEAHVYGVGALFGLVALLALLALALLPWRCPPGAPCLALL-DLL 405
Query: 510 VLVASALRSAYMLTDPYGSQARLGVRGGLVLYNLPFPLLLTALAALTLLGLGAGLPPPLQ 569
+L A R+ + D YG + RL L+L +LP P L L LL P P +
Sbjct: 406 LLSAGTTRAFPLFYDAYGHRDRLPALAWLLLQDLPLPCLAAGLGLACLL---LARPRPPR 462
Query: 570 NPLLLGAVALVHGVGLLATDLLSTWS-----VLNLLTQGLSCAWGAAVALGTLCLC---- 620
P L A+ L+ G+GL A L + + L L ++GL A+ AA G L
Sbjct: 463 CPTGLAALLLL-GLGLAAAAALGSAAHRPLRPLRLASRGLH-AFLAAFLSGLLLALSCWG 520
Query: 621 -RRRLLDGPRGWD----ASPGP----------------RLLAVAGALGLLASGLQLAAAL 659
RRR P G A+P P R VAG GLL+ LQ L
Sbjct: 521 GRRRRAGAPLGGSGFKGATPLPQGRSPFAPRESWRRAARTAPVAGTFGLLSGALQGYEVL 580
Query: 660 WLYPGPGRVG-RFSWAWWGVHFWLRLLELTWALALALAAVAAARPRPPTEHACWAKLMRL 718
G+ G W WW LRL E+ AL LAL + A P CWAKL RL
Sbjct: 581 HALGYGGQSGLEGPWPWWAFQLGLRLGEVGVALPLALLGLYPALCSPRVPPRCWAKLFRL 640
Query: 719 ACPAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASL 778
S P P GP + + ++ R AE QL +G
Sbjct: 641 -----SPGHAAPLLPGGWVTGPPD----KEPLGSAIARGDAELLQLCA-LAGPGPDLLLQ 690
Query: 779 GRGPQGGPGLSRNGVGPAPSLSE-------LDLRPPSPINLSRSIDAALFREHLVRDSVF 831
G G +G G + N PAPS + +D RPPSPINL RSI+ AL E L+ +F
Sbjct: 691 GGGCRGFEGAAAN---PAPSPASSPCSDYTVDFRPPSPINLRRSIEEALCSEALLAPGLF 747
Query: 832 Q---------RCGLRGLASPPPGGALRPRRG--SHPKAELD-------DAGSSLLRGRCR 873
Q GL AS GG R G S P A + AGSS+ G
Sbjct: 748 QGPAFEDALPGLGLYRTASLGTGGRASERSGEASGPAAPPELPSPGAWPAGSSVSSGSFC 807
Query: 874 SLS 876
LS
Sbjct: 808 GLS 810
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 79.0 bits (193), Expect = 2e-14
Identities = 82/330 (24%), Positives = 119/330 (36%), Gaps = 31/330 (9%)
Query: 141 AVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTS 200
A P P G + + P + VA++ SL+ E + A ++ VP +
Sbjct: 861 AAVPAPEGTAVVAALVPFPHEDILVASIV-SLEEEDVTAA------AVSAPERATVPAVT 913
Query: 201 PSDHQG---------PPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPD 251
S +G P T + + + + + GF A T++D P+
Sbjct: 914 VSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEED-GTPE 972
Query: 252 VGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPG---PPPK 308
G V P V++ E +PD A R P E A E +SP P P+
Sbjct: 973 -GPVTPATTVHAPE---EPDTAAVRVSTPEEP----ASPAAAVPTPEEPTSPAAAVPTPE 1024
Query: 309 QADLPDAKDSPGPQPTDPPAS-EAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSL 367
+ P A P +PT P A+ P+ P+ P A +P SP E P +P +
Sbjct: 1025 EPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAA 1084
Query: 368 IPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRA 427
+P P +P +P P A P P S PA V P V T
Sbjct: 1085 VPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPAS--PAAAVPTPEEPASPAAAVPTPEE 1142
Query: 428 LGQPPPPEPTASSMASAPASSPPANATAPP 457
P P PT ASA + P +A P
Sbjct: 1143 PAFPAPAVPTPEESASAAVAVPTPEESASP 1172
Score = 65.9 bits (159), Expect = 2e-10
Identities = 68/270 (25%), Positives = 96/270 (35%), Gaps = 25/270 (9%)
Query: 211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVY--SQEPGA 268
+ GT + PV + A T ++PA+P P E + P
Sbjct: 964 ITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAVPTP 1023
Query: 269 QPDLALARSLPPAEE-----LPVETPKR-----AGAEVSWEVSSPG---PPPKQADLPDA 315
+ + A ++PP EE V TP+ A E +SP P P++ P A
Sbjct: 1024 EEPTSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAA 1083
Query: 316 KDSPGPQPTDPPAS-EAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSD- 373
+PT P A+ P+ P+ P A +P SP E P +P + +P P +
Sbjct: 1084 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEP 1143
Query: 374 --PGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQP 431
P PAV E A E P + P P A + + T A P
Sbjct: 1144 AFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEPTSPAASVP 1203
Query: 432 PPP------EPTASSMASAPASSPPANATA 455
P E S AS P S PA+ A
Sbjct: 1204 TPAAMVATLEEFTSPAASVPTSEEPASLAA 1233
Score = 60.5 bits (145), Expect = 8e-09
Identities = 101/473 (21%), Positives = 158/473 (33%), Gaps = 57/473 (12%)
Query: 25 ALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENP----RADSHRNSDVRHAPA 80
AL P P E + I +P P+G+ + A FP S DV A A
Sbjct: 846 ALDAALPSPEEGTSIAAVPA--PEGT--AVVAALVPFPHEDILVASIVSLEEEDVT-AAA 900
Query: 81 EEMPEK---PVASPLGPALYGPKAAQGAQRERLP-----VTDDLQMAQGPSSHGWTGPLD 132
PE+ P + P AA + E P +T + A S W
Sbjct: 901 VSAPERATVPAVTVSVPEGTAAVAAVSSPEETAPAVAAAITQEGMSAVAGFSPEWAALAI 960
Query: 133 SQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKT 192
+ + +++ PV P P + P P A
Sbjct: 961 TVPITEEDGTPEGPVTPATTVHAPEEPDTAAVRVSTPEEPASPAAAVPTPEEPTSPAAAV 1020
Query: 193 KSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDV 252
+ PTSP+ PP S + V P EE AA P T ++P +P
Sbjct: 1021 PTPEEPTSPAAAVPPPEEPTSPAAAVPTP--------EEPTSPAAAVP--TPEEPTSPAA 1070
Query: 253 GSVPPVEVVY--SQEPGAQPDLALARSLPPAEE-----LPVETPKRAGAEVSWEVSSPGP 305
P E + P + + A ++P EE V TP+ + + + P
Sbjct: 1071 AVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPASPAAAVPTPEEP 1130
Query: 306 PPKQADLPDAKDSPGPQPTDPPASEA---------PDRPSKPERAAMNGADPISPQRVRG 356
A +P ++ P P P E+ P+ + P A A+ S V
Sbjct: 1131 ASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVA 1190
Query: 357 AVEAPGTPKSLIPGP----------SDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPA 406
+E P +P + +P P + P +V +E P E P P +
Sbjct: 1191 TLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAA--AV 1248
Query: 407 PPVQAPSTSRRGLI--RVTTQRALGQPPPPEPTASSMASAPASSPPANATAPP 457
P ++ P++S ++ + A P P EP + + A + P + A A P
Sbjct: 1249 PTLEEPTSSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVP 1301
Score = 54.7 bits (130), Expect = 4e-07
Identities = 95/403 (23%), Positives = 131/403 (32%), Gaps = 47/403 (11%)
Query: 77 HAPAE-EMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQE 135
HAP E + V++P PA P AA E P+S P +
Sbjct: 982 HAPEEPDTAAVRVSTPEEPA--SPAAAVPTPEE-------------PTSPAAAVPTPEEP 1026
Query: 136 LLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSR 195
AV P +PT A VP + P +E
Sbjct: 1027 TSPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVP 1086
Query: 196 VP--PTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVG 253
P PTSP+ P S + V P EE AA P T ++PA+P
Sbjct: 1087 TPEEPTSPAAAVPTPEEPTSPAAAVPTP--------EEPASPAAAVP--TPEEPASP-AA 1135
Query: 254 SVP-------PVEVVYSQEPGAQPDLALA---RSLPPAEELPVETPKRAGAEVSWEVSSP 303
+VP P V + E A +A+ S PA +P + A V + P
Sbjct: 1136 AVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAAVVATLEEP 1195
Query: 304 GPPPKQADLPDAKDSPGPQPTDPPAS-EAPDRPSKPERAAMNGADPISPQRVRGAVEAPG 362
P P A + + T P AS + P+ A N +P SP +E P
Sbjct: 1196 TSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPT 1255
Query: 363 TPKSLIPGP---SDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGL 419
+ + + P S P +V E P E P P + P P V A +
Sbjct: 1256 SSAAAVLTPEELSSPAASVPTPEEPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPT 1315
Query: 420 IRVTTQRALGQPPPPEPTASSM----ASAPASSPPANATAPPL 458
V A PP E + + SA S P + P+
Sbjct: 1316 PEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPV 1358
Score = 42.7 bits (99), Expect = 0.002
Identities = 81/380 (21%), Positives = 115/380 (30%), Gaps = 42/380 (11%)
Query: 53 SEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVAS-PLGPALYGPKAAQGAQRERLP 111
+ P A PE P S P E P P A+ P P AA E
Sbjct: 1001 ASPAAAVPTPEEP------TSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPTS 1054
Query: 112 VTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPS 171
+ + P+S P + AV +PT A VP
Sbjct: 1055 PAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTP 1114
Query: 172 LQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEE 231
+ P +E P P S S V P E
Sbjct: 1115 EEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAA 1174
Query: 232 HLQEAAQGPHF-----TQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPV 286
+ A+ F T ++P +P P +V + E P A S+P +EE
Sbjct: 1175 AVPTPAESASFAAVVATLEEPTSPAASVPTPAAMVATLEEFTSP----AASVPTSEE--- 1227
Query: 287 ETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGA 346
A ++ VS+P P A + P + A P+ S P +
Sbjct: 1228 ------PASLAAAVSNPEEPTSPAAAVPTLEEP---TSSAAAVLTPEELSSPAASVPTPE 1278
Query: 347 DPISPQRVRGAVEAPGTPKSLIPGP--------SDPGPAVNRTESPMGALQPDEAEEWPG 398
+P SP +E P +P + +P P S P P V P A+ P E G
Sbjct: 1279 EPASPAAAVSNLEEPASPAAAVPTPEVAAIPAASVPTPEV--PAIPAAAVPPMEEVSPIG 1336
Query: 399 RP----QSHPPAPPVQAPST 414
P +H + P+ T
Sbjct: 1337 VPFLGVSAHTDSVPISEEGT 1356
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 72.4 bits (176), Expect = 2e-12
Identities = 125/472 (26%), Positives = 159/472 (33%), Gaps = 90/472 (19%)
Query: 17 LPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDV- 75
L + + P R P P IP P PKG+ P P +P+ S
Sbjct: 911 LSMTSSSPKKARATPAP---KGIPASPS--PKGA----PTPPAATPPSPKGGPATPSPKW 961
Query: 76 RHAPAEEMPEKPVASPLGPALYG---PKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLD 132
P P P P P+ G P AA + P T PS G P
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPAT--------PSPKGAPTP-- 1011
Query: 133 SQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKT 192
P P G P T P + A+ PP+ PP +G A T
Sbjct: 1012 ------PAVTPPSPKGSPAATPFP-------KGASTPPAAT--------PPSPKGSPAAT 1050
Query: 193 KSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDV 252
+P +P+ P TL S G P L+G + +G T AP
Sbjct: 1051 P--LPKGAPTT---PAATLPSPKGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAP-- 1103
Query: 253 GSVPPVEVVYSQEPG-AQPDLALA----RSLPPAEELPVETPKRAGAEVSWEVSSPGP-- 305
+PP S + G A P A + PP+ + + TP GA + + P P
Sbjct: 1104 --MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKG 1161
Query: 306 -----PPKQADLPDAKDSPGPQP--TDPPASEAPDRPSKPERAAMNGADPISPQRVRGAV 358
PPK A A P P+ P AP P+ + G SP+
Sbjct: 1162 GLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKG----- 1216
Query: 359 EAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHP--------PAPPVQ 410
AP TP + P P G A T SP GA P P P+ P P PP
Sbjct: 1217 -APTTPAATPPSPKG-GLA---TPSPKGA--PTTPAATPPSPKGGPATPPPKGAPTPPAA 1269
Query: 411 APSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
P + + GL T G P P T S PA+SPP A PP P
Sbjct: 1270 TPPSLKGGL---ATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPP 1318
Score = 64.7 bits (156), Expect = 4e-10
Identities = 108/464 (23%), Positives = 156/464 (33%), Gaps = 92/464 (19%)
Query: 21 GTGPALGRGFP---RPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRAD-SHRNSDVR 76
GT P G P P P +P P G + P P A SH+
Sbjct: 1325 GTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAM 1384
Query: 77 HAPAEEMPE---KPVASPLGPALY--GPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPL 131
P+ + P P PA+ PK A PVT + A PS T P
Sbjct: 1385 TPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPAT-----PVTRE--GAATPSKGDLTPPA 1437
Query: 132 DSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAK 191
+ L++ P G P P++ A PPS + PP + +
Sbjct: 1438 VTPVSLKKAPATSAPKGGPAT---PSSKGDPTLPAVTPPSPKE-------PPAPKQVATS 1487
Query: 192 TKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPD 251
+ + P +P+ P V S + P +++DP AP
Sbjct: 1488 SSPKKAPATPAPMGAPTLPAVIPSSPKEVPATPS-----------------SRRDPIAPT 1530
Query: 252 VGSVPPVEVVYSQEPGA-QPDLALARSLPPAEELP-------VETPKRAGAEVSW-EVSS 302
++ + P P AL +PPA +P + TPK A A S E SS
Sbjct: 1531 A------TLLSKKTPATLAPKEAL---IPPAMTVPSPKKTPAIPTPKEAPATPSSKEASS 1581
Query: 303 P----------GPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQ 352
P P PK+ +P A SP P+ P + P P K P SP
Sbjct: 1582 PPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSP- 1640
Query: 353 RVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAP 412
P TP SL P+ P + MGA P ++ P + + AP
Sbjct: 1641 --------PVTPSSLKDSPTSPASVTCK----MGATVPQASKGLPAKKGPTALKEVLVAP 1688
Query: 413 STSRRGLIRVTTQR--------ALGQPPPPEPTASSMASAPASS 448
+ +I T++ A P P+P+A + + P S+
Sbjct: 1689 APESTPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLST 1732
Score = 63.9 bits (154), Expect = 7e-10
Identities = 119/484 (24%), Positives = 155/484 (32%), Gaps = 61/484 (12%)
Query: 31 PRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPA-EEMPEKPVA 89
P P S P PKGS + P P P A P+ + P P A
Sbjct: 1027 PFPKGASTPPAATPPSPKGSPAATPLPKGA-PTTPAATLPSPKGGPATPSLKGAPTPPAA 1085
Query: 90 SPL----GPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPH 145
+P GPA PK A P + +A P T P + + P
Sbjct: 1086 TPPSPKGGPATPSPKGAP-MPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPP 1144
Query: 146 PVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQ 205
P G P T T P + +AT PP P GL + P T +
Sbjct: 1145 PKGAP-TTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPP 1203
Query: 206 GPPHTLVSHS--GTVKRPVL---EGQGGFEEHLQEAAQGPHFTQQDPAAPDVG-SVPPVE 259
P L + S G P +GG + A P P +P G + PP +
Sbjct: 1204 SPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGA--PTTPAATPPSPKGGPATPPPK 1261
Query: 260 VVYSQEPGAQPDLALARSLPP-------------------AEELPVETPKRAGAEVSWEV 300
+ P L + PP A P P A
Sbjct: 1262 GAPTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAATPPSPK 1321
Query: 301 SSPG-PPPKQADLPDAKDSPGPQ---------------PTDPPASEAPDRPSK-PERAAM 343
SPG PPPK A P A P P+ PT P + E P P+ P
Sbjct: 1322 GSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG 1381
Query: 344 NGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGR--PQ 401
P SP+R G P S P P A + GA P + + P P
Sbjct: 1382 PAMTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPV 1441
Query: 402 SHPPAPPVQAP-----STSRRG--LIRVTTQRALGQPPPPEPTASSMASAPASSPPANAT 454
S AP AP + S +G + T + +PP P+ A+S + A + PA
Sbjct: 1442 SLKKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMG 1501
Query: 455 APPL 458
AP L
Sbjct: 1502 APTL 1505
Score = 62.4 bits (150), Expect = 2e-09
Identities = 112/464 (24%), Positives = 162/464 (34%), Gaps = 61/464 (13%)
Query: 33 PLENSEIPMIPGAHP--KGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVAS 90
P + + P HP +G++ + P P A S +N+ A PE P +
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 91 PLGPALYGPKAAQGAQR-ERLPVTDDLQ-MAQGPSS-----HGWTGPLDSQELLQQEAVA 143
P P+L G ++ + + T L +A P G + S+ L A +
Sbjct: 735 P-SPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADS 793
Query: 144 PHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSD 203
P P+G ++ P T R + + P P + S +P S S
Sbjct: 794 PSPLG---VSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEA-------SFLPENSLSF 843
Query: 204 HQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYS 263
+HS T P +G + +G ++ P V ++P +
Sbjct: 844 QGSKDSPATTHSPTPPSP--KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLP-----FP 896
Query: 264 QEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQ- 322
+E A P A PA + +PK+A A + + P PK A P A P P+
Sbjct: 897 KEGPATP----APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKG 952
Query: 323 -PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAP-GTPKSLIPGPSDPGP---- 376
P P AP P+ + G SP +GA P TP S GP+ P P
Sbjct: 953 GPATPSPKWAPTPPAATPPSPKGGPATPSP---KGAPTPPAATPPSPKGGPATPSPKGAP 1009
Query: 377 ------------AVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQ--APSTSRRGLIR- 421
+ T P GA P A P P+ P A P+ AP+T L
Sbjct: 1010 TPPAVTPPSPKGSPAATPFPKGASTPPAAT--PPSPKGSPAATPLPKGAPTTPAATLPSP 1067
Query: 422 ---VTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
T G P PP T S PA+ P A PP P
Sbjct: 1068 KGGPATPSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPAATPP 1111
Score = 60.1 bits (144), Expect = 1e-08
Identities = 120/504 (23%), Positives = 155/504 (30%), Gaps = 78/504 (15%)
Query: 16 LLPLLGTGPALGRGFPRPLENSEIPMIPGAH-PKGSVGSEPQAFDVFPENPRADSHRNSD 74
+LPL+ P F + EIP+ P A K S+G EP + + NS
Sbjct: 559 VLPLVQAAPKNSPSFQSTSSSPEIPLSPEATLAKKSLG-EPLPIGKPASSMTSPLGVNSS 617
Query: 75 VRHAPAEEMPEKPVASP-LGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDS 133
+ A P L +L P A P A+G S++ T S
Sbjct: 618 ASVIKTDSYAGPDSAGPLLKSSLITPTVAAFPLESADPAGVAPTTAKGTSTYTTTA---S 674
Query: 134 QELLQQEAVAP--HPVGHPHLTFIPTTPRRQLRVATVP---------------------- 169
L ++AP HPV LT +P P P
Sbjct: 675 PFLEGTVSLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSV 734
Query: 170 --PSLQHEG----------------------QEGQWPPRDEGLKAKTKSRVPPTSPSDHQ 205
PSL G + P D G A S+ T +D
Sbjct: 735 PSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSP 794
Query: 206 GPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQE 265
P VS T + P +G G P P +P S P + Q
Sbjct: 795 SPLGVSVSPQ-TKRPPTKKGSAG--------PDTPIGNLSSPVSPVEASFLPENSLSFQ- 844
Query: 266 PGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSP---GPPPKQADLPDAKDSPG-P 321
G++ A S P TP V+ P P P +LP K+ P P
Sbjct: 845 -GSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATP 903
Query: 322 QPTDPPA-SEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNR 380
P PA S P K P SP TP S GP+ P P
Sbjct: 904 APKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAP 963
Query: 381 TESPMGALQPDEAEEWPGRPQ-SHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTAS 439
T A P + P P P PP P + + G T G P PP T
Sbjct: 964 TPP---AATPPSPKGGPATPSPKGAPTPPAATPPSPKGG---PATPSPKGAPTPPAVTPP 1017
Query: 440 SMASAPASSP-PANATAPPLRWGP 462
S +PA++P P A+ PP P
Sbjct: 1018 SPKGSPAATPFPKGASTPPAATPP 1041
Score = 57.4 bits (137), Expect = 6e-08
Identities = 85/351 (24%), Positives = 115/351 (32%), Gaps = 52/351 (14%)
Query: 144 PHPVGHPHLTFIPTTPRRQLRVAT---VPPSLQHEGQE---GQWPPRDEGLKAKTKSRVP 197
P P P L+ ++P++ +P S +G PP +G A +
Sbjct: 903 PAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWA 962
Query: 198 PTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPP 257
PT P+ PP S G P +G A P + PA P P
Sbjct: 963 PTPPA--ATPP----SPKGGPATPSPKGAP------TPPAATPPSPKGGPATPSPKGAPT 1010
Query: 258 VEVVYSQEPGAQP---DLALARSLPPA------EELPVETPKRAGAEVSWEVSSPGPPPK 308
V P P S PPA + P TP GA + + P P
Sbjct: 1011 PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG 1070
Query: 309 QADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE------APG 362
A P K +P P PP+ + P+ A M A +P +G + AP
Sbjct: 1071 PAT-PSLKGAPTPPAATPPSPKGGPATPSPKGAPMPPA--ATPPSPKGGLATPPHKGAPT 1127
Query: 363 TPKSLIPGPSD----------PGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAP 412
TP + P P P SP G L + P P + PP+P
Sbjct: 1128 TPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLA 1187
Query: 413 STSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPL 463
+ S +G TT A PP P +P +P A PP G L
Sbjct: 1188 TPSPKGA--PTTPAAT----PPSPKGGLATPSPKGAPTTPAATPPSPKGGL 1232
Score = 55.5 bits (132), Expect = 2e-07
Identities = 89/371 (23%), Positives = 120/371 (32%), Gaps = 68/371 (18%)
Query: 150 PHLTFIPTTPRRQLRVATVPPSLQHEGQEG-QWPPRDEGLKAKTKSRVP---PTSPSDHQ 205
P T PT P + A P ++ +G PP++ + P P +P+ Q
Sbjct: 850 PATTHSPTPPSP--KGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGPATPAPKQ 907
Query: 206 GPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAA-------------PDV 252
P ++ S S R +G A+ P PAA P
Sbjct: 908 APALSMTSSSPKKARATPAPKG------IPASPSPKGAPTPPAATPPSPKGGPATPSPKW 961
Query: 253 GSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE-----TPKRAGAEVSWEVSSPGPP- 306
PP S + G PPA P TP GA V+ P P
Sbjct: 962 APTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTPPSPKG 1021
Query: 307 -------PKQADLPDAKDSPGPQPTD---PPASEAPDRPSKPERAAMNGADPISPQRVRG 356
PK A P A P P+ + P AP P+ + G P +P ++G
Sbjct: 1022 SPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGG--PATPS-LKG 1078
Query: 357 AVEAPG-TPKSLIPGPSDPGPA------VNRTESPMGALQPDEAEEWPGRPQSHPPAP-- 407
A P TP S GP+ P P SP G L + P P + PP+P
Sbjct: 1079 APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKG 1138
Query: 408 -------------PVQAPSTSRRGLIRVTTQRALGQPP--PPEPTASSMASAPASSPPAN 452
P P + + GL + A P PP P +P +P
Sbjct: 1139 GLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTP 1198
Query: 453 ATAPPLRWGPL 463
A PP G L
Sbjct: 1199 AATPPSPKGGL 1209
Score = 32.0 bits (71), Expect = 2.9
Identities = 31/97 (31%), Positives = 38/97 (39%), Gaps = 13/97 (13%)
Query: 718 LACPAPSGK----SEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPS-SGAW 772
LA P+P G + P P A P GA + + P+ G LATP GA
Sbjct: 1232 LATPSPKGAPTTPAATPPSPKGGPATPPPKGAPTPPAATP----PSLKGGLATPPHKGAP 1287
Query: 773 GSAASLGRGPQGGPGLSRNGVGPAPSLSELDLRPPSP 809
A P+GGP S P P + PPSP
Sbjct: 1288 NPAVVTPPSPKGGPATSPPKGAPTPPAA----TPPSP 1320
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 69.7 bits (169), Expect = 1e-11
Identities = 97/387 (25%), Positives = 149/387 (38%), Gaps = 57/387 (14%)
Query: 94 PALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGH--PH 151
PA GP A Q LP PS+ L++ + L Q A G P
Sbjct: 572 PAPAGPAATTVLQGVTLP----------PSA---VAMLNTPDGLVQPATPAAATGEAAPV 618
Query: 152 LTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKT--KSRVPPTSPSDHQGPPH 209
LT P P+ V+T P L + + Q PP+ +A ++ P SP P
Sbjct: 619 LTVQPA-PQAPPAVST-PLPLGLQQPQAQQPPQAPTPQAAAPPQATTPQPSPGLASSPEK 676
Query: 210 TLVSHSGTVKRPVLEGQGGFEEHLQE-------AAQGPHFTQQDPAAPDVGSVPPVEVVY 262
++ + + Q + L + +A+GPH + PA+ V + PP +
Sbjct: 677 IVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGPHLSV--PASVIVSAPPPAQDPA 734
Query: 263 SQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPP-----PKQADLPDAKD 317
P A+ L P ++ P P+ A + PGP P QA L D+
Sbjct: 735 PATPVAK-GAGLGPQAPDSQASPAPAPQIPAAA---PLKGPGPSSSPSLPHQAPLGDSPH 790
Query: 318 SPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSD---P 374
P P PT PP+ PS+P+ + ++P P +AP T + + P
Sbjct: 791 LPSPHPTRPPSRP----PSRPQSVSRPPSEP--PLHPCPPPQAPPTLPGIFVIQNQLGVP 844
Query: 375 GPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPV----QAPSTSRRGLIRVTTQRALGQ 430
PA N + G QP P RPQS PP P+ P +S + +++ + +
Sbjct: 845 PPASNPAPTAPGPPQP------PLRPQSQPPEGPLPPAPHLPPSSTSSAVASSSETS-SR 897
Query: 431 PPPPEPTASSMASAPASSPPANATAPP 457
P P P+ + P+ P + T PP
Sbjct: 898 LPAPTPSDFQLQFPPSQGPHKSPTPPP 924
Score = 59.7 bits (143), Expect = 1e-08
Identities = 82/295 (27%), Positives = 106/295 (35%), Gaps = 47/295 (15%)
Query: 170 PSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKR--PVLEGQG 227
PSL H+ G P + SR PP+ P PP H + P L G
Sbjct: 777 PSLPHQAPLGDSPHLPSPHPTRPPSR-PPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF 835
Query: 228 GFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE 287
+ L P + P AP PP+ P +QP LPPA LP
Sbjct: 836 VIQNQL---GVPPPASNPAPTAPGPPQ-PPLR------PQSQPPEG---PLPPAPHLPPS 882
Query: 288 TPKRAGA---EVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMN 344
+ A A E S + +P P Q P ++ P PT PP P+ P
Sbjct: 883 STSSAVASSSETSSRLPAPTPSDFQLQFPPSQ-GPHKSPTPPPTLHLVPEPAAP------ 935
Query: 345 GADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTES-PMGALQPDEAEEWPGRPQSH 403
P P R V P P P + R P G + ++A P PQ+
Sbjct: 936 ---PPPPPRTFQMVTTP------FPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTS 986
Query: 404 PPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPL 458
P+ +P+ S + V+ GQ P PTA S A APA P A PPL
Sbjct: 987 TSLGPLTSPAAS----VLVS-----GQAPSGTPTAPSHAPAPA--PMAATGLPPL 1030
Score = 43.5 bits (101), Expect = 0.001
Identities = 79/321 (24%), Positives = 111/321 (34%), Gaps = 40/321 (12%)
Query: 141 AVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTS 200
A+ P +LTF+ Q V + P+ + + PP A T PP
Sbjct: 386 ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAPALQANVFKQPP------ATTTGAAPPQP 439
Query: 201 PSDHQGPPHT-LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAP-DVGSVPPV 258
P P L++ ++ P G + L A QQ A P +VG
Sbjct: 440 PGALSKPMSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQLPQQLSALPANVGG---- 495
Query: 259 EVVYSQEPG------AQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADL 312
+++ + P A P L P PV P +GA + +S+ P Q
Sbjct: 496 QILAAAAPHTGGQLIANPILTNQNLAGPLSLGPVLAP-HSGAHSAHILSAA---PIQVGQ 551
Query: 313 PDAKDSP------------GPQPTDPPASEAPDRPSKPERAA--MNGADPISPQRVRGAV 358
P P P P P A+ + P A +N D + A
Sbjct: 552 PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAMLNTPDGLVQPATPAAA 611
Query: 359 EAPGTPKSLI-PGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRR 417
P + P P P PAV+ T P+G QP +A++ P P APP
Sbjct: 612 TGEAAPVLTVQPAPQAP-PAVS-TPLPLGLQQP-QAQQPPQAPTPQAAAPPQATTPQPSP 668
Query: 418 GLIRVTTQRALGQPPPPEPTA 438
GL + LGQPP PTA
Sbjct: 669 GLASSPEKIVLGQPPSATPTA 689
Score = 37.4 bits (85), Expect = 0.069
Identities = 42/145 (28%), Positives = 54/145 (37%), Gaps = 31/145 (21%)
Query: 305 PPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTP 364
PPP A L A+ P P P PP + P P +P+R
Sbjct: 1333 PPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHP--------PPAAPER----------- 1373
Query: 365 KSLIPGPSDPGPAVNRT--ESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRV 422
K L P P + +T E+ G P+ GR + PAP + GLIR
Sbjct: 1374 KPLGTAPHCPRLPLRKTYRENVGGPGAPEGTP--AGRARGGSPAPLPAKVDEATSGLIRE 1431
Query: 423 TT-------QRALGQPPPPEPTASS 440
QR L + PPPEP AS+
Sbjct: 1432 LAAVEDELYQRML-KGPPPEPAASA 1455
Score = 34.7 bits (78), Expect = 0.45
Identities = 85/386 (22%), Positives = 117/386 (30%), Gaps = 95/386 (24%)
Query: 18 PLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH 77
PL G GP+ P + P +P HP S P P P++ S
Sbjct: 767 PLKGPGPSSSPSLPHQAPLGDSPHLPSPHPT-RPPSRP------PSRPQSVSR------- 812
Query: 78 APAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELL 137
P E P P P P L ++
Sbjct: 813 -PPSEPPLHPCPPPQAPP----------------------------------TLPGIFVI 837
Query: 138 QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDE----------G 187
Q + P P +P T P P+ LR + PP EG PP
Sbjct: 838 QNQLGVPPPASNPAPT-APGPPQPPLRPQSQPP-------EGPLPPAPHLPPSSTSSAVA 889
Query: 188 LKAKTKSRVPPTSPSDHQGP-PHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD 246
++T SR+P +PSD Q P + H P L HL +
Sbjct: 890 SSSETSSRLPAPTPSDFQLQFPPSQGPHKSPTPPPTL--------HL----------VPE 931
Query: 247 PAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVS-SPGP 305
PAAP ++V + P AL + K GA + + S S GP
Sbjct: 932 PAAPPPPPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGP 991
Query: 306 -PPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTP 364
A + + +P PT AP P A G P+ P + T
Sbjct: 992 LTSPAASVLVSGQAPSGTPT------APSHAPAPAPMAATGLPPLLPAENKAFASNLPTL 1045
Query: 365 KSLIPGPSDPG-PAVNRTESPMGALQ 389
S PG P+ + ES + L+
Sbjct: 1046 NVAKAASSGPGKPSGLQYESKLSGLK 1071
Score = 34.3 bits (77), Expect = 0.59
Identities = 56/216 (25%), Positives = 69/216 (31%), Gaps = 58/216 (26%)
Query: 279 PPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQ-PTDPPASEAPDRPSK 337
PPA E P R P PPP + D P P P P AP P
Sbjct: 1336 PPATLKVAEPPPRP----------PPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPRL 1385
Query: 338 PERAAM--NGADPISPQ-----RVRGAVEAPGTPK---------------------SLIP 369
P R N P +P+ R RG AP K ++
Sbjct: 1386 PLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQRMLK 1445
Query: 370 GPSDPGPAVNRTESPMGALQPD-EAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTT---- 424
GP P PA + + G PD EA P + +P V S S T
Sbjct: 1446 GPP-PEPAASAAQ---GTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDDTLTEHL 1501
Query: 425 ----------QRALGQPPPPEPTASSMASAPASSPP 450
Q+A G+ P P ++ A PAS PP
Sbjct: 1502 QSAIDSILNLQQAPGRTPAPSYPHAASAGTPASPPP 1537
>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
Length = 416
Score = 67.4 bits (163), Expect = 6e-11
Identities = 107/479 (22%), Positives = 153/479 (31%), Gaps = 92/479 (19%)
Query: 12 LLLLLLPLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSV---GSEPQAFDVFPENPRAD 68
+LL+LL + + + + E P + +P+G+ G++PQ P P+
Sbjct: 1 MLLILLSVALLALSSAQNLNEDVSQEESPSLIAGNPQGAPPQGGNKPQGPPSPPGKPQGP 60
Query: 69 SHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWT 128
+ + + P P P GP G QG P QGP G
Sbjct: 61 PPQGGN-----QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--------QGPPPQG-- 105
Query: 129 GPLDSQELLQQEAVAPH-PVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEG 187
++ +P P G P P Q + PP + Q PP G
Sbjct: 106 ----------DKSRSPRSPPGKPQGP--PPQGGNQPQGPPPPPG------KPQGPPPQGG 147
Query: 188 LKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDP 247
K + P P QGPP + S + + P + QG QG + Q P
Sbjct: 148 NKPQG-----PPPPGKPQGPPPQGDNKSRSSRSPPGKPQG-------PPPQGGNQPQGPP 195
Query: 248 AAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEE-----------LPVETPKRAGAEV 296
P PP + +P P + PP + P P + G +
Sbjct: 196 PPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQP 253
Query: 297 SWEVSSPG----PPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQ 352
PG PPP+ + P PG PP + R S+ G P
Sbjct: 254 QGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGN 313
Query: 353 RVRGAVEAPGTPKSLIP-------GPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPP 405
+ +G PG P+ P GP PG + P G + A PG+PQ
Sbjct: 314 QPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP--QGPPPQGGSKSRSARSPPGKPQG--- 368
Query: 406 APPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLR 464
P Q + +G PPPP AP + P PP P R
Sbjct: 369 --PPQQEGNNPQG------------PPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSR 413
Score = 42.7 bits (99), Expect = 0.002
Identities = 78/339 (23%), Positives = 110/339 (32%), Gaps = 43/339 (12%)
Query: 24 PALGRGFPRPLENSEIPMIPGAHPKGSV---GSEPQAFDVFPENPRADSHRNSDVRHAPA 80
P +G P + S P P P+G G++PQ P P+ + + P
Sbjct: 95 PGKPQGPPPQGDKSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 154
Query: 81 EEMPEKPVASPLGPALYGPKAAQGAQ----RERLPVTDDLQMAQGPSSHGWTGPLDSQEL 136
P P GP G ++ ++ + + P QGP P
Sbjct: 155 ------PPGKPQGPPPQGDNKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGK-PQGPPPQ 207
Query: 137 LQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHE-----GQEGQWPPRDEGL--- 188
+ P P G P P + + A PP G + Q PP G
Sbjct: 208 GGNKPQGPPPPGKPQGP--PPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQG 265
Query: 189 ---KAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQ 245
+ K + PP P QGPP S S + + P + QG QG + Q
Sbjct: 266 PPPQGGNKPQGPPP-PGKPQGPPPQGGSKSRSSRSPPGKPQG-------PPPQGGNQPQG 317
Query: 246 DPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPA----EELPVETPKRAGAEVSWEVS 301
P P PP + +P P + PP P + E +
Sbjct: 318 PPPPPGKPQGPPPQG--GNKPQGPPPPGKPQGPPPQGGSKSRSARSPPGKPQGPPQQEGN 375
Query: 302 SP-GPPPKQADLPDAKDSP-GPQPTDPPASEAPDRPSKP 338
+P GPPP P +P QP PP RPS+P
Sbjct: 376 NPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGGRPSRP 414
>gi|56243590 WD repeat domain 33 isoform 1 [Homo sapiens]
Length = 1336
Score = 67.0 bits (162), Expect = 8e-11
Identities = 110/419 (26%), Positives = 145/419 (34%), Gaps = 71/419 (16%)
Query: 18 PLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH 77
PL+G P +G P P EN G P+G + P P+ R + H
Sbjct: 775 PLMGLNPRGMQGPPGPRENQ------GPAPQGMIMGHP------PQEMRGPHPPGGLLGH 822
Query: 78 APAEEMPEKPVASPLGP----ALYGP----KAAQGAQRERLPVTDDLQMAQGPSSHGWTG 129
P E + + GP ++ GP + G+Q ++ P L P G G
Sbjct: 823 GPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPPQGSLGP---PPQGGMQG 879
Query: 130 PLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPS-LQHEGQEGQWPPRDEGL 188
P Q Q A PHP P IP ++ + P + EGQ PP GL
Sbjct: 880 PPGPQGQ-QNPARGPHPSQGP----IPFQQQKTPLLGDGPRAPFNQEGQSTGPPPLIPGL 934
Query: 189 KAK-TKSRVPPTSPS--------DHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQG 239
+ + R+PP +P D +GPP+ H G + E GG EH E +G
Sbjct: 935 GQQGAQGRIPPLNPGQGPGPNKGDSRGPPN---HHMGPMSERRHEQSGG-PEHGPE--RG 988
Query: 240 PHFTQQDPAAPDV--GSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVS 297
P QD P G P +S+ PD L E P+ E
Sbjct: 989 PFRGGQDCRGPPDRRGPHPDFPDDFSRPDDFHPDKRFGHRLREFEGRGGPLPQ----EEK 1044
Query: 298 WEVSSPGPP--PKQADLPD------AKDSPGPQPTDPPASEA-PDRPSKP------ERAA 342
W PGPP P + + A+ PG P E P P P E +
Sbjct: 1045 WRRGGPGPPFPPDHREFSEGDGRGAARGPPGAWEGRRPGDERFPRDPEDPRFRGRREESF 1104
Query: 343 MNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQ 401
GA P R AP + PGP D GP N S A D G P+
Sbjct: 1105 RRGAPP------RHEGRAPPRGRDGFPGPEDFGPEENFDASEEAARGRDLRGRGRGTPR 1157
Score = 37.7 bits (86), Expect = 0.053
Identities = 84/371 (22%), Positives = 113/371 (30%), Gaps = 108/371 (29%)
Query: 121 GPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFI---PTTPRRQLRVATVPPSLQHEGQ 177
GP GP+ + Q PHP + P P+ Q R PP Q GQ
Sbjct: 584 GPQPFPGQGPMSQ---IPQGFQQPHPSQQMPMNMAQMGPPGPQGQFR----PPGPQ--GQ 634
Query: 178 EG-QWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEA 236
G Q PP +G + + P P QGPP G + + G G + H
Sbjct: 635 MGPQGPPLHQG-GGGPQGFMGPQGP---QGPPQ------GLPRPQDMHGPQGMQRH---- 680
Query: 237 AQGPH--FTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGA 294
GPH Q P P S P + PG Q
Sbjct: 681 -PGPHGPLGPQGPPGPQGSSGPQGHMGPQGPPGPQG------------------------ 715
Query: 295 EVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRV 354
+ GPP Q L GPQ PP ++ P P
Sbjct: 716 ----HIGPQGPPGPQGHL-------GPQ--GPPGTQGMQGPPGPR--------------- 747
Query: 355 RGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPP---VQA 411
++ P P + GP G ++ P+ L P + PG ++ PAP +
Sbjct: 748 --GMQGPPHPHGIQGGPGSQGIQGPVSQGPLMGLNPRGMQGPPGPRENQGPAPQGMIMGH 805
Query: 412 PSTSRR------GLIRVTTQ--------RALGQPP-------PPEPTASSMASAPASSPP 450
P R GL+ Q R + PP PP+ S PP
Sbjct: 806 PPQEMRGPHPPGGLLGHGPQEMRGPQEIRGMQGPPPQGSMLGPPQELRGPPGSQSQQGPP 865
Query: 451 ANATAPPLRWG 461
+ PP + G
Sbjct: 866 QGSLGPPPQGG 876
>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
tract binding protein associated) [Homo sapiens]
Length = 707
Score = 65.5 bits (158), Expect = 2e-10
Identities = 73/240 (30%), Positives = 88/240 (36%), Gaps = 51/240 (21%)
Query: 176 GQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQE 235
GQ G PP + + + PP P Q PPH H
Sbjct: 52 GQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPH--------------------- 90
Query: 236 AAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPA-EELPVETPKRAGA 294
PH QQ P P S P V +Q PG P + S PPA P TP +GA
Sbjct: 91 --PQPHQQQQPPPPPQDSSKP----VVAQGPGPAPGVG---SAPPASSSAPPATPPTSGA 141
Query: 295 EV-SWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSK-----PERAAMNGADP 348
S +P PPP P PG P PP+S P P + P AA+ G P
Sbjct: 142 PPGSGPGPTPTPPPAVTSAP-----PGAPPPTPPSSGVPTTPPQAGGPPPPPAAVPGPGP 196
Query: 349 ISPQRVRGAVEAPGTPK-SLIPGPSDPGPAVNRTESPMGALQPDE--AEEWPGRPQSHPP 405
P++ G PG PK +PG PG +P G +P E G Q HPP
Sbjct: 197 -GPKQGPG----PGGPKGGKMPGGPKPGGGPG-LSTPGGHPKPPHRGGGEPRGGRQHHPP 250
Score = 49.3 bits (116), Expect = 2e-05
Identities = 42/136 (30%), Positives = 50/136 (36%), Gaps = 12/136 (8%)
Query: 303 PGPPPKQADLPDAKDSPGPQ---PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE 359
P PPP Q P PQ P PP P + +P + + P+ Q G
Sbjct: 61 PPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQ---GPGP 117
Query: 360 APGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPP-APPVQAPSTSRRG 418
APG S P S PA T P P S PP APP PS+
Sbjct: 118 APGVG-SAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSG--- 173
Query: 419 LIRVTTQRALGQPPPP 434
+ T +A G PPPP
Sbjct: 174 -VPTTPPQAGGPPPPP 188
Score = 48.9 bits (115), Expect = 2e-05
Identities = 61/244 (25%), Positives = 78/244 (31%), Gaps = 57/244 (23%)
Query: 225 GQGGFEEHLQEAAQGPHFTQ-QDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEE 283
G+GG + + G Q + P P G P + P Q + PP +
Sbjct: 24 GRGGLHD-FRSPPPGMGLNQNRGPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQP 82
Query: 284 LPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQP---TDPPASEAPDRPSKPER 340
P + P + P PPP+ + P PGP P + PPAS +
Sbjct: 83 PPHQPPPHPQPH---QQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSS--------- 130
Query: 341 AAMNGADPISPQRVRGAVEAPGTPKSLIPGPS-DPGPAVNRTESPMGALQPDEAEEWPGR 399
A P +P G P PGP+ P PAV T +P PG
Sbjct: 131 -----APPATPP-------TSGAPPGSGPGPTPTPPPAV--TSAP------------PGA 164
Query: 400 PQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSP-PANATAPPL 458
P PP PP TT G PPPP P P P +
Sbjct: 165 P---PPTPPSSGVP---------TTPPQAGGPPPPPAAVPGPGPGPKQGPGPGGPKGGKM 212
Query: 459 RWGP 462
GP
Sbjct: 213 PGGP 216
Score = 48.1 bits (113), Expect = 4e-05
Identities = 55/207 (26%), Positives = 68/207 (32%), Gaps = 45/207 (21%)
Query: 168 VPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRP------ 221
+PP H+ Q+ Q PP+ PP P HQ PPH P
Sbjct: 60 IPPPPPHQQQQ-QPPPQQP----------PPQQPPPHQPPPHPQPHQQQQPPPPPQDSSK 108
Query: 222 --VLEGQG---GFEEHLQEAAQGPHFTQQDPAAPDVGSVP-----PVEVVYSQEPGAQPD 271
V +G G G ++ P T AP GS P P V S PGA P
Sbjct: 109 PVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPP-GSGPGPTPTPPPAVTSAPPGAPPP 167
Query: 272 LALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEA 331
PP+ +P P+ G P PPP P GP P P +
Sbjct: 168 T------PPSSGVPTTPPQAGG---------PPPPPAAVPGPGPGPKQGPGPGGPKGGKM 212
Query: 332 PDRPSKPERAAMN--GADPISPQRVRG 356
P P ++ G P P R G
Sbjct: 213 PGGPKPGGGPGLSTPGGHPKPPHRGGG 239
>gi|209977046 fibrous sheath CABYR binding protein [Homo sapiens]
Length = 825
Score = 64.7 bits (156), Expect = 4e-10
Identities = 106/466 (22%), Positives = 161/466 (34%), Gaps = 67/466 (14%)
Query: 25 ALGRGFPRPLENSEIPMIPGAH--PKGSVGSEPQAFDVFPENPRADS----HRNSDVRHA 78
A + PRP E + + + P P + V + P A+ ++++
Sbjct: 277 ATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVKVQPPPAEEAPLVEFPAEIQPP 336
Query: 79 PAEEMPEK-------PVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPL 131
AEE P P ++ P+ P E+ P + L + PS+ P+
Sbjct: 337 SAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGEIRSPSAQ--KAPI 394
Query: 132 DSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEG--LK 189
+ Q L + A+ P P + +A V P L E PR+E L+
Sbjct: 395 EVQPLPAEGALEEAPAK-------VEPPTVEETLADVQPLLPEEA------PREEARELQ 441
Query: 190 AKTKSRVPPT-SPSDHQGP-PHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGP--HFTQQ 245
T P +P++ Q P P + + + +L + A+ P T
Sbjct: 442 LSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPLSEETSA 501
Query: 246 DPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGP 305
+ A +V S P E ++E A+ L LA PA+E P E E S E +
Sbjct: 502 EEAHAEVQS-PLAEETTAEEASAEIQL-LAAIEAPADETPAEAQSPLSEETSAEEA---- 555
Query: 306 PPKQADLPDAKD---SPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPG 362
P + P AK P PP+ E + A S + V+ P
Sbjct: 556 -PAEVQSPSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEVQPP- 613
Query: 363 TPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRV 422
P P P PA E +QP AEE P Q P P +AP+
Sbjct: 614 -PAEEAPAEVQPPPA----EEAPAEVQPPPAEEAPAEVQ---PPPAEEAPAEV------- 658
Query: 423 TTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLRRVLS 468
QPPP E + + PA PA + P P+ L+
Sbjct: 659 -------QPPPAEEAPAEVQPPPAEEAPAEVQSLPAEETPIEETLA 697
Score = 51.2 bits (121), Expect = 5e-06
Identities = 88/393 (22%), Positives = 132/393 (33%), Gaps = 75/393 (19%)
Query: 130 PLDSQELLQQEAVA---PHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDE 186
P Q L +EA A P P H+ P+T + A ++ + Q PP +E
Sbjct: 266 PAKIQPPLVEEATAKAEPRPAEETHVQVQPST--EETPDAEAATAVAENSVKVQPPPAEE 323
Query: 187 GLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD 246
+ + + P PS + P L++ + P E + EE E P ++
Sbjct: 324 APLVEFPAEIQP--PSAEESPSVELLAE---ILPPSAE-ESPSEEPPAEILPPP--AEKS 375
Query: 247 PAAPDVGSV-------PPVEVVYSQEPGAQPDLALARSLPPAEE--------LPVETPKR 291
P+ +G + P+EV GA + P EE LP E P+
Sbjct: 376 PSVELLGEIRSPSAQKAPIEVQPLPAEGALEEAPAKVEPPTVEETLADVQPLLPEEAPRE 435
Query: 292 AGAEVSWEVSSPGPP---PKQADLPDAKDSPGPQP---------TDPPASEAPDRPSKP- 338
E+ + P P + P K++ + T+PPA E P P
Sbjct: 436 EARELQLSTAMETPAEEAPTEFQSPLPKETTAEEASAEIQLLAATEPPADETPAEARSPL 495
Query: 339 ------ERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDE 392
E A P++ + A + I P+D PA +SP+ +
Sbjct: 496 SEETSAEEAHAEVQSPLAEETTAEEASAEIQLLAAIEAPADETPA--EAQSPLS--EETS 551
Query: 393 AEEWPGRPQSHPPA-------------PPVQAPSTSRRGLIRVTTQRALG---------- 429
AEE P QS P A PP +T+ + A
Sbjct: 552 AEEAPAEVQS-PSAKGVSIEEAPLELQPPSGEETTAEEASAAIQLLAATEASAEEAPAEV 610
Query: 430 QPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
QPPP E + + PA PA PP P
Sbjct: 611 QPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAP 643
Score = 48.1 bits (113), Expect = 4e-05
Identities = 83/391 (21%), Positives = 136/391 (34%), Gaps = 50/391 (12%)
Query: 98 GPKAAQGAQR-ERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHP--VGHPHLTF 154
G K + A+ E + V+ +LQ HG S LQ + + V T
Sbjct: 36 GSKGSYSAKAYESIRVSSELQQTWTKRKHGQEMTSKS---LQTDTIVEEKKEVKLVEETV 92
Query: 155 IPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAK-------------TKSRVPPTSP 201
+P +R A + L Q+ + PP ++ K T +PP
Sbjct: 93 VPEEKSADVREAAI--ELPESVQDVEIPPNIPSVQLKMDRSQQTSRTGYWTMMNIPPVEK 150
Query: 202 SDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDP-------AAPDVGS 254
D + + S + RP E+ L+ + G F + P + ++G
Sbjct: 151 VDKEQQTYFSESEIVVISRPDSSSTKSKEDALKHKSSGKIFASEHPEFQPATNSNEEIGQ 210
Query: 255 VPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPD 314
++QE P + L L +PV + G+ V S+ PP P
Sbjct: 211 KNISRTSFTQETKKGPPVLLEDELREEVTVPV---VQEGSAVKKVASAEIEPPSTEKFP- 266
Query: 315 AKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDP 374
AK P + ++A RP++ + + +P A + K + P P++
Sbjct: 267 AKIQ--PPLVEEATAKAEPRPAEETHVQVQPSTEETPDAEAATAVAENSVK-VQPPPAEE 323
Query: 375 GPAV---------NRTESP----MGALQPDEAEEWPGR--PQSHPPAPPVQAPSTSRRGL 419
P V + ESP + + P AEE P P P P ++PS G
Sbjct: 324 APLVEFPAEIQPPSAEESPSVELLAEILPPSAEESPSEEPPAEILPPPAEKSPSVELLGE 383
Query: 420 IRVTTQRALGQPPPPEPTASSMASAPASSPP 450
IR + + P P ++ APA P
Sbjct: 384 IRSPSAQKAPIEVQPLPAEGALEEAPAKVEP 414
Score = 38.9 bits (89), Expect = 0.024
Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 31/167 (18%)
Query: 279 PPAEELPVETPKRAGAEVSWEVSSP--GPPPKQADLPDAKDSPGPQPTDPPASEAPDRPS 336
PPAEE P E E EV P P + P A+++P + PPA EAP
Sbjct: 613 PPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEEAPA-EVQPPPAEEAPAEVQ 671
Query: 337 KPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEW 396
P A EAP +SL P++ P E + A+ A++
Sbjct: 672 PPP-----------------AEEAPAEVQSL---PAEETP----IEETLAAVHSPPADDV 707
Query: 397 PGRPQS-HPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMA 442
P S +PP T + A PPP E T A
Sbjct: 708 PAEEASVDKHSPPADLLLTEE---FPIGEASAEVSPPPSEQTPEDEA 751
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 64.7 bits (156), Expect = 4e-10
Identities = 103/415 (24%), Positives = 139/415 (33%), Gaps = 69/415 (16%)
Query: 78 APAEEMPEKPVA-SPLGPALYGPKAAQGAQRERLPV-TDDLQMAQGPSSHGWTGPLDSQE 135
AP P KP + +P PAL P G PV T D P+ PL
Sbjct: 668 APFSPPPSKPRSPNPAAPALAAPAVVPG------PVSTTDASPQSPPTPQTTLTPLQESP 721
Query: 136 LL---QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEG----QWPPRDEGL 188
++ Q +P P HP P P ++ V PS +E WPP
Sbjct: 722 VISKDQSPPPSPPPSYHP-----PPPPTKKPEVVVEAPSASETAEEPLQDPNWPPP---- 772
Query: 189 KAKTKSRVPPTSPSDHQ------GPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHF 242
PP +P + PP +V P G G E + A
Sbjct: 773 --------PPPAPEEQDLSMADFPPPEEAFF---SVASPEPAGPSGSPELVSSPAASSSS 821
Query: 243 TQ----QDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSL-------PPAEEL--PVETP 289
Q P +PD PP S PG L + PP E++ P+ TP
Sbjct: 822 ATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTP 881
Query: 290 KRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMN----- 344
V +PG P A P A P + AS P PS AA+
Sbjct: 882 SLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVP-APSSGLHAAVRLKACS 940
Query: 345 --GADPISPQRVRGAVEA----PGTPKSLIPGPSDPGPAVNRTESPMGA-LQPDEAEEWP 397
++ +S + G EA P +P S G + E P+ Q D
Sbjct: 941 LAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLV 1000
Query: 398 GRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPAN 452
+S P QAP S + V + ++G PPP P S + P ++PP N
Sbjct: 1001 AELRSISEQRPPQAPKKSPKAPPPVARKPSVGVPPPASP--SYPRAEPLTAPPTN 1053
Score = 62.0 bits (149), Expect = 3e-09
Identities = 127/522 (24%), Positives = 180/522 (34%), Gaps = 123/522 (23%)
Query: 22 TGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAE 81
TG + G G N +PG P GS P++ PE + S S P
Sbjct: 539 TGGSEGAGAAPCPPNPANSWVPGLSPGGS-RRPPRS----PERTLSPSSGYSSQSGTPT- 592
Query: 82 EMPEKPVASPLGPALYGPKAAQGAQRERLP------------VTDDLQMAQGPSSHGWTG 129
+P K +A P PA P AQ + ER+ +T + P+ +G
Sbjct: 593 -LPPKGLAGP--PA--SPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSG 647
Query: 130 PLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQ-------LRVATVPPSLQHEGQEGQWP 182
P L + + PHP + P+ PR A VP + Q P
Sbjct: 648 PQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSP 707
Query: 183 P---------RDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRP--VLEGQGGFEE 231
P ++ + +K +S P PS H PP T K+P V+E E
Sbjct: 708 PTPQTTLTPLQESPVISKDQSPPPSPPPSYHPPPPPT--------KKPEVVVEAPSA-SE 758
Query: 232 HLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEEL-PVETPK 290
+E Q P++ P AP+ + DL++A PP E V +P+
Sbjct: 759 TAEEPLQDPNWPPPPPPAPE-----------------EQDLSMADFPPPEEAFFSVASPE 801
Query: 291 RAGAEVSWE-VSSPGPPPKQADL-----PDAKDSPGPQPTDPPASEAPDRPSK-PERAAM 343
AG S E VSSP A P + D P P PAS AP +K P++ +
Sbjct: 802 PAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPV 861
Query: 344 N------------GADPISP---QRVR-GAVEAPGTPKSLIPGPSDPGPAVNRTESPMGA 387
GA ++P Q VR +V APG + GPS P + R S +
Sbjct: 862 GCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRAS 921
Query: 388 LQPDEAE---------------------EWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQR 426
P + P P P PP ST+ + + +
Sbjct: 922 PVPAPSSGLHAAVRLKACSLAASEGLSSAQPNGPPEAEPRPPQSPASTASFIFSKGSRKL 981
Query: 427 ALGQPPPPEPTA-----------SSMASAPASSPPANATAPP 457
L +P PE A S P +P + APP
Sbjct: 982 QLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSPKAPP 1023
Score = 53.5 bits (127), Expect = 9e-07
Identities = 77/279 (27%), Positives = 105/279 (37%), Gaps = 50/279 (17%)
Query: 194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVG 253
SR PP SP P S SGT P L +G GP PA+P
Sbjct: 567 SRRPPRSPERTLSPSSGYSSQSGT---PTLPPKG---------LAGP------PASPGKA 608
Query: 254 SVPPVEVVYS-QEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADL 312
P E V S + PGA +L SL + P + R+G ++ + P +
Sbjct: 609 QPPKPERVTSLRSPGASVSSSLT-SLCSSSSDPAPSD-RSGPQILTPLGDRFVIPPHPKV 666
Query: 313 PDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPS 372
P +P P P S P P+ A + G P+S + ++P TP++ + P
Sbjct: 667 P----APFSPPPSKPRSPNPAAPALAAPAVVPG--PVST--TDASPQSPPTPQTTLT-PL 717
Query: 373 DPGPAVNRTESPMGALQPDEAEEWPGRPQS-HPPAPP-------VQAPSTSRRGLIRVTT 424
P +++ +SP P P S HPP PP V+APS S +
Sbjct: 718 QESPVISKDQSPP-----------PSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQD 766
Query: 425 QRALGQPPP-PEPTASSMASAPASSPPANATAPPLRWGP 462
PPP PE SMA P + A P GP
Sbjct: 767 PNWPPPPPPAPEEQDLSMADFPPPEEAFFSVASPEPAGP 805
Score = 37.7 bits (86), Expect = 0.053
Identities = 44/171 (25%), Positives = 61/171 (35%), Gaps = 25/171 (14%)
Query: 318 SPGPQPTDPPAS-EAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPG- 375
SP P+ P +S + + +G+ S G E+ S++P P
Sbjct: 401 SPQPRSRHPSSSSDTWSHSQSSDTIVSDGSTLSSKGGSEGQPESSTASNSVVPPPQGGSG 460
Query: 376 ---PAVNRTESPMGALQPDEAEEWPGRPQS-----HPPAPPVQAPSTSRRGLIRVTTQRA 427
P+ T L + + GR S PP PP + S +RGL
Sbjct: 461 RGSPSGGSTAEASDTLSIRSSGQLSGRSVSLRKLKRPPPPPRRTHSLHQRGL--AVPDGP 518
Query: 428 LGQPPPPE----------PT---ASSMASAPASSPPANATAPPLRWGPLRR 465
LG PP PE PT + +AP PAN+ P L G RR
Sbjct: 519 LGLPPKPERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRR 569
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 62.8 bits (151), Expect = 2e-09
Identities = 100/417 (23%), Positives = 156/417 (37%), Gaps = 64/417 (15%)
Query: 38 EIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALY 97
E+P + V E + V P+ P A + +V P E +PEK VA P P +
Sbjct: 10715 ELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEV---PKEVVPEKKVAVPKKPEVP 10771
Query: 98 GPKAAQGAQR---ERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPH-----PVGH 149
K + ++ E P + A+ P + P +E+ +E +AP PV
Sbjct: 10772 PAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEP---EEIAPEEEIAPEEEKPVPVAE 10828
Query: 150 ---PHLT--FIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGL-KAKTKSRVPPTSPSD 203
P + +P P++ + VP + E + P ++ + K K K R PP P+
Sbjct: 10829 EEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPEPEKVIEKPKLKPRPPPPPPA- 10887
Query: 204 HQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYS 263
PP VK + + + ++ + E Q P + P G +++
Sbjct: 10888 ---PPKE------DVKEKIFQLKAIPKKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPE 10938
Query: 264 QEPGAQPDLALARSLP--PAEELPVETPKRAGAEVSWEVSSPGPP--------------- 306
++P + ++ L L P EE P PK+ V P PP
Sbjct: 10939 RKPEPKEEVVLKSVLRKRPEEEEPKVEPKKLEKVKKPAVPEPPPPKPVEEVEVPTVTKRE 10998
Query: 307 ---PKQADLPDAKDS---PGPQPTDPPASEAPD---RPSKPERAAMNGADPISPQRVRGA 357
P+ +P+ K + P P+P P +E P +PE + A P++ V
Sbjct: 10999 RKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPTPI--AAPVTVPVVGKK 11056
Query: 358 VEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPST 414
EA PK P P V P P EAE RP S PP +AP T
Sbjct: 11057 AEAKA-PKEEAAKPKGPIKGV-----PKKTPSPIEAERRKLRPGSGGEKPPDEAPFT 11107
Score = 60.8 bits (146), Expect = 6e-09
Identities = 115/507 (22%), Positives = 184/507 (36%), Gaps = 81/507 (15%)
Query: 33 PLENSEIPMIPGAHPKGSVGSEPQAFDV-----FPENPRADSHRNSDVRHAPAEEMPEK- 86
P + ++P P V P+ V PE PR + +V P E +PEK
Sbjct: 10451 PPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVRVPEEPRVPPTKVPEVL-PPKEVVPEKK 10509
Query: 87 ----PVASPLGPALYGPKAAQGAQRER-LPVTDDLQMAQGPSSHGWTGPLDSQELLQQEA 141
P P P P+A + E+ +PV + P+ E EA
Sbjct: 10510 VPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEA 10569
Query: 142 VAPHPVGHPHLTFIPTTPRRQLRVATVP--PSLQHEGQEGQWPPRDEGLKAKTKSRVPPT 199
+ P P P +P P+ + VP P + E + P + + + K VPP
Sbjct: 10570 IPPKPESPP--PEVPEAPKEVVPEKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPP- 10626
Query: 200 SPSDHQGPPHTL--VSHSGTVKRPVLEG---------QGGFEEHLQEAAQGPH---FTQQ 245
P + PP + V ++ V E FEE + A + P +
Sbjct: 10627 -PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEP 10685
Query: 246 DPAAPDVGSVPPVEVVYSQEPGA----QPDLA------LARSLPPAEELPVETPKRAGA- 294
+PAAP +VPP + V ++ A +P+L + + + P +++P+ PK+ A
Sbjct: 10686 EPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAP 10745
Query: 295 -----EVSWEV---------SSPGPPPKQAD---------------LPDAKDSPGPQPTD 325
EV EV P PP + +P+ +SP P+ +
Sbjct: 10746 PAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYE 10805
Query: 326 PPASEAPDRPSKPERAA-MNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESP 384
P AP+ PE + A+ P+ AV P PK +IP P + + E+P
Sbjct: 10806 EPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAV--PEEPKKIIP--EKKVPVIKKPEAP 10861
Query: 385 MGAL-QPDEAEEWPG---RPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASS 440
+P++ E P RP PPAPP + L + ++ +P PE +
Sbjct: 10862 PPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVELT 10921
Query: 441 MASAPASSPPANATAPPLRWGPLRRVL 467
P P + P V+
Sbjct: 10922 PLKVPGGEKKVRKLLPERKPEPKEEVV 10948
Score = 59.3 bits (142), Expect = 2e-08
Identities = 92/418 (22%), Positives = 148/418 (35%), Gaps = 66/418 (15%)
Query: 70 HRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTG 129
HR +V A E+ EKP A P GP + ++ + P T + + P+
Sbjct: 10419 HRVIEVFEAEEVEVFEKPKAPPKGPEI-----SEKIIPPKKPPTKVVPRKEPPAK---VP 10470
Query: 130 PLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQL---RVATVPPSLQHEGQEGQWPPRDE 186
+ + +++++ P P P +++ + VPP+ + E + P +
Sbjct: 10471 EVPKKIVVEEKVRVPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPK 10530
Query: 187 GLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD 246
+ + K VPP P + PP K P + E+ + EA P +
Sbjct: 10531 EVVPEKKVPVPP--PKKPEVPP---------TKVPEVPKAAVPEKKVPEAI--PPKPESP 10577
Query: 247 PAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPP 306
P P+V P V + P A P E PV+ P+ A EV E P PP
Sbjct: 10578 P--PEVPEAPKEVVPEKKVPAAPP--------KKPEVTPVKVPE-APKEVVPEKKVPVPP 10626
Query: 307 PKQADLPDAKDSPGPQPTDP-----------PASEAPDRPSKPERAAMN--GADPISPQR 353
PK+ ++P K P+ P P S P+ +PE A+ A+ +
Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPE 10686
Query: 354 VRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRP-----QSHPPAPP 408
+ PK +P P + E P + E P + P APP
Sbjct: 10687 PAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPP 10746
Query: 409 VQAPSTSRRGLIRVTTQRALGQPPPPE---------PTASSMASAPASSPPANATAPP 457
+ P + V ++ + P PE P + PA P A +PP
Sbjct: 10747 AKVPEVPK----EVVPEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPP 10800
Score = 47.4 bits (111), Expect = 7e-05
Identities = 98/446 (21%), Positives = 153/446 (34%), Gaps = 74/446 (16%)
Query: 33 PLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEK-----P 87
P S P +P A PK V E + P+ P + V AP E +PEK P
Sbjct: 10572 PKPESPPPEVPEA-PK-EVVPEKKVPAAPPKKPEVTPVK---VPEAPKEVVPEKKVPVPP 10626
Query: 88 VASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVA---- 143
P P P+ + A E+ + P + P +E+ +E A
Sbjct: 10627 PKKPEVPPTKVPEVPKVAVPEKKVPEAIPPKPESPPPEVFEEP---EEVALEEPPAEVVE 10683
Query: 144 -PHPVGHPHLTFIPTTPRRQLRVATV-------PPSLQHEGQEGQWPPRDEGLKAKTKSR 195
P P P +T P P + + V PP E + P + L K
Sbjct: 10684 EPEPAAPPQVTVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPE 10743
Query: 196 VPPTS----------------PSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQG 239
PP P + PP + K+PVLE + + E A+
Sbjct: 10744 APPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPE---VPKKPVLEEKPAVP--VPERAES 10798
Query: 240 PH---FTQQDPAAPDVGSVP----PVEVVYSQEPGAQPDLALA--RSLPPAEELPVETPK 290
P + + + AP+ P PV V +EP P + + P +++PV
Sbjct: 10799 PPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKP 10858
Query: 291 RAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPIS 350
A PPPK+ + + P +P PP AP + E+ A P
Sbjct: 10859 EA------------PPPKEPEPEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQLKAIP-- 10904
Query: 351 PQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQ 410
+ E P P+ + P + + +P+ EE + P +
Sbjct: 10905 ---KKKVPEKPQVPEKVELTPLKVPGGEKKVRKLLPERKPEPKEEVVLKSVLR-KRPEEE 10960
Query: 411 APSTSRRGLIRVTTQRALGQPPPPEP 436
P + L +V + A+ +PPPP+P
Sbjct: 10961 EPKVEPKKLEKV-KKPAVPEPPPPKP 10985
Score = 40.4 bits (93), Expect = 0.008
Identities = 66/322 (20%), Positives = 116/322 (36%), Gaps = 35/322 (10%)
Query: 157 TTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSG 216
T P + + V VP + + + PP KA + +VP P + PP +
Sbjct: 9787 TEPEKPIPVKPVPE--EPVPTKPKAPPAKVLKKAVPEEKVPVPIPKKLKPPPPKVPEEPK 9844
Query: 217 TV---KRPVLEGQGGFEEHLQEAAQGPH-----FTQQDPAAPDVGSVPPVEVVYSQEPGA 268
V K + + E+ + AA+ P ++ P PPV V +
Sbjct: 9845 KVFEEKIRISITKREKEQVTEPAAKVPMKPKRVVAEEKVPVPRKEVAPPVRVPEVPKELE 9904
Query: 269 QPDLALARSLPP-AEELPVETPKRAGAE----VSWEVSSPGPPPKQADLP------DAKD 317
++A + EE VE + E ++ E P P K ++P + K
Sbjct: 9905 PEEVAFEEEVVTHVEEYLVEEEEEYIHEEEEFITEEEVVPVIPVKVPEVPRKPVPEEKKP 9964
Query: 318 SPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVR-GAVEAPGTPKSLIPGPSDPGP 376
P P+ + P ++ P+ P KPE + P++ + + P PK +P P P
Sbjct: 9965 VPVPKKKEAPPAKVPEVPKKPEEK----VPVLIPKKEKPPPAKVPEVPKKPVPEEKVPVP 10020
Query: 377 AVNRTESPMGAL-----QPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIR----VTTQRA 427
+ E+P + +P ++ P APP + P ++ + +
Sbjct: 10021 VPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEEKKPTPVPKK 10080
Query: 428 LGQPPPPEPTASSMASAPASSP 449
+ PPP P P + P
Sbjct: 10081 VEAPPPKVPKKREPVPVPVALP 10102
Score = 38.1 bits (87), Expect = 0.041
Identities = 45/222 (20%), Positives = 76/222 (34%), Gaps = 45/222 (20%)
Query: 233 LQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRA 292
+ + + P + P P V PV + EP A + + P E+ PV PK+
Sbjct: 9278 ISKRVEPPPKVPELPEKPAPEEVAPVPIPKKVEPPAPKVPEVPKKPVPEEKKPVPVPKK- 9336
Query: 293 GAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDP-PASEAPDRPSKPERAAMNGADPISP 351
P PPK +P+ P P+ P P ++ + P G ++
Sbjct: 9337 ---------EPAAPPK---VPEVPKKPVPEEKIPVPVAKKKEAPPAKVPEVQKGV--VTE 9382
Query: 352 QRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQA 411
+++ + +P +P E P + P+E + P + + PP P V
Sbjct: 9383 EKITIVTQREESPPPAVP------------EIPKKKV-PEERKPVPRKEEEVPPPPKVP- 9428
Query: 412 PSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANA 453
AL + P PE + +PP A
Sbjct: 9429 ---------------ALPKKPVPEEKVAVPVPVAKKAPPPRA 9455
Score = 37.4 bits (85), Expect = 0.069
Identities = 40/190 (21%), Positives = 69/190 (36%), Gaps = 24/190 (12%)
Query: 244 QQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSP 303
+++ P+ VPP E +E P+ + + P +P P+ +V P
Sbjct: 10143 EEEEIPPEEEEVPPEEEYVPEEEEFVPEEEVLPEVKPKVPVPAPVPEIKKKVTEKKVVIP 10202
Query: 304 ----GPP------PKQAD-----LPDAKDSPGPQPTDPPASEAPDRPSKPERA-AMNGAD 347
PP PK+ + LP ++ + T+ P E PE ++ +
Sbjct: 10203 KKEEAPPAKVPEVPKKVEEKRIILPKEEEVLPVEVTEEPEEEPISEEEIPEEPPSIEEVE 10262
Query: 348 PISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAP 407
++P RV P K +P P P + E+P + EE P AP
Sbjct: 10263 EVAPPRV------PEVIKKAVP--EAPTPVPKKVEAPPAKVSKKIPEEKVPVPVQKKEAP 10314
Query: 408 PVQAPSTSRR 417
P + P ++
Sbjct: 10315 PAKVPEVPKK 10324
Score = 34.7 bits (78), Expect = 0.45
Identities = 38/147 (25%), Positives = 57/147 (38%), Gaps = 26/147 (17%)
Query: 229 FEEHLQEAAQGPHFTQQDPAAPDVGSVPPV-EVVYSQEPGAQPDLALARSLPPAEELPVE 287
+EEH + + T+ + P V PV E +P A P L +++P E++PV
Sbjct: 9779 YEEHEE------YITEPEKPIP----VKPVPEEPVPTKPKAPPAKVLKKAVPE-EKVPVP 9827
Query: 288 TPKRAGAEVSWEVSSPGPP-----PKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAA 342
PK+ P PP PK+ + S + + A P KP+R
Sbjct: 9828 IPKKL---------KPPPPKVPEEPKKVFEEKIRISITKREKEQVTEPAAKVPMKPKRVV 9878
Query: 343 MNGADPISPQRVRGAVEAPGTPKSLIP 369
P+ + V V P PK L P
Sbjct: 9879 AEEKVPVPRKEVAPPVRVPEVPKELEP 9905
Score = 32.3 bits (72), Expect = 2.2
Identities = 43/153 (28%), Positives = 62/153 (40%), Gaps = 22/153 (14%)
Query: 257 PVEVVYSQEPGA--QPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPD 314
P EV QE +P + PP ++P E PK+ + E P P PK+ +P
Sbjct: 9551 PAEVTERQEKKIVLKPKIPAKIEEPPPAKVP-EAPKK----IVPEKKVPAPVPKKEKVPP 9605
Query: 315 AK-----DSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAV---EAPGTPKS 366
K P P+ PP + P P + ++V AV EAP PK+
Sbjct: 9606 PKVPEEPKKPVPEKKVPPKVIKMEEP-LPAKVTERHMQITQEEKVLVAVTKKEAP--PKA 9662
Query: 367 LIPGPSDPGPAVNRTESPMGALQPDEAEEWPGR 399
+ P +P AV E + L+P EE P +
Sbjct: 9663 RV--PEEPKRAV--PEEKVLKLKPKREEEPPAK 9691
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/293 (25%), Positives = 98/293 (33%), Gaps = 33/293 (11%)
Query: 175 EGQEGQWPPRDEGLKAKTKSRVPP--TSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEH 232
E Q + PP + +K S PP ++P Q PH + G+ P G
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH----NRGSPPVP------GGPRQ 212
Query: 233 LQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRA 292
P F A GS+ + S +P L S ++ P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA-LDDKPPPPPPPV 271
Query: 293 GAEVSWEVSSPGPPPKQADLPDAKDSPGPQ-----PTDPPASEAPDRPSKPERAAMNGAD 347
G S + PPP Q + P +P P P PP P P P ++ N
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 348 PISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAP 407
P PQR + TP PG S P P P P + PGR PP P
Sbjct: 332 PRLPQRNLSL--SSSTPPLPSPGRSGPLPP------PPSERPPPPVRDPPGRSGPLPPPP 383
Query: 408 PVQAPSTSRRGL-------IRVTTQRALGQPPPPEPTASSMASAPASSPPANA 453
PV ++ R L R P PP P A AP PP+ +
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 51.2 bits (121), Expect = 5e-06
Identities = 66/243 (27%), Positives = 80/243 (32%), Gaps = 46/243 (18%)
Query: 240 PHFTQQDPAAPDVGSVPP-VEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSW 298
P + P PDVGS P + P R PP P +
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP---------- 213
Query: 299 EVSSPGPPP------KQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQ 352
SPGP P + L P + P S P P P RA ++ P P
Sbjct: 214 ---SPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA-LDDKPPPPPP 269
Query: 353 RV-------RGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPP 405
V R AV P + P PS P P+ + P P P S P
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP------------PPPPPSRPG 317
Query: 406 APPVQAPSTSRRGLIRVTTQRAL----GQPPPPEPTASS-MASAPASSPPANATAPPLRW 460
PP+ PS+S QR L PP P P S + P+ PP PP R
Sbjct: 318 PPPL-PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
Query: 461 GPL 463
GPL
Sbjct: 377 GPL 379
Score = 35.8 bits (81), Expect = 0.20
Identities = 57/221 (25%), Positives = 73/221 (33%), Gaps = 60/221 (27%)
Query: 156 PTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQG-----PPHT 210
P P+R L +++ P L G+ G PP S PP D G PP
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPP--------PPSERPPPPVRDPPGRSGPLPPPP 383
Query: 211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYS-QEPGAQ 269
VS +G+ R + PA P + S V+ S P
Sbjct: 384 PVSRNGSTSRAL------------------------PATPQLPSRSGVDSPRSGPRPPLP 419
Query: 270 PDLALARSLPPAEELPVETPKRAG-----AEVSWEVSSPGPPPKQADLPDAKDSPGPQPT 324
PD A + PP P T R G E WE P +DLP
Sbjct: 420 PDRPSAGAPPPP---PPSTSIRNGFQDSPCEDEWESRFYFHP--ISDLP----------- 463
Query: 325 DPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPK 365
PP S P + A N + S +R RGA P P+
Sbjct: 464 -PPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 34.3 bits (77), Expect = 0.59
Identities = 68/268 (25%), Positives = 81/268 (30%), Gaps = 54/268 (20%)
Query: 729 VPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGRGPQGGPGL 788
VP P + P N G+ P G PS G RG G G
Sbjct: 187 VPSTPRPIQSSPHNRGS------------PPVPGGPRQPSPGPTPPPFPGNRGTALGGGS 234
Query: 789 SRNGVGPAPSLSELDLRPPSPINLSRSID--------AALFREHLVRDSV---------- 830
R P S S RPP P SR++D R + R++V
Sbjct: 235 IRQS--PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 831 ----FQRCGLRGLASPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRV------ 880
R A PPP RP P + + + L R SLS
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352
Query: 881 -RGPVPQHVVEAPDGAAAAASGSS-----------LDSFSRGSLKISWNPWRHGLSSVDS 928
GP+P E P G S S SR P R G+ S S
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 929 LPLDELPSTVQLLPAPTPAPDSTAARQG 956
P LP AP P P ST+ R G
Sbjct: 413 GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 62.8 bits (151), Expect = 2e-09
Identities = 75/293 (25%), Positives = 98/293 (33%), Gaps = 33/293 (11%)
Query: 175 EGQEGQWPPRDEGLKAKTKSRVPP--TSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEH 232
E Q + PP + +K S PP ++P Q PH + G+ P G
Sbjct: 163 EPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPH----NRGSPPVP------GGPRQ 212
Query: 233 LQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRA 292
P F A GS+ + S +P L S ++ P P
Sbjct: 213 PSPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA-LDDKPPPPPPPV 271
Query: 293 GAEVSWEVSSPGPPPKQADLPDAKDSPGPQ-----PTDPPASEAPDRPSKPERAAMNGAD 347
G S + PPP Q + P +P P P PP P P P ++ N
Sbjct: 272 GNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDET 331
Query: 348 PISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAP 407
P PQR + TP PG S P P P P + PGR PP P
Sbjct: 332 PRLPQRNLSL--SSSTPPLPSPGRSGPLPP------PPSERPPPPVRDPPGRSGPLPPPP 383
Query: 408 PVQAPSTSRRGL-------IRVTTQRALGQPPPPEPTASSMASAPASSPPANA 453
PV ++ R L R P PP P A AP PP+ +
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTS 436
Score = 51.2 bits (121), Expect = 5e-06
Identities = 66/243 (27%), Positives = 80/243 (32%), Gaps = 46/243 (18%)
Query: 240 PHFTQQDPAAPDVGSVPP-VEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSW 298
P + P PDVGS P + P R PP P +
Sbjct: 164 PQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQP---------- 213
Query: 299 EVSSPGPPP------KQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQ 352
SPGP P + L P + P S P P P RA ++ P P
Sbjct: 214 ---SPGPTPPPFPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRA-LDDKPPPPPP 269
Query: 353 RV-------RGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPP 405
V R AV P + P PS P P+ + P P P S P
Sbjct: 270 PVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPP------------PPPPPSRPG 317
Query: 406 APPVQAPSTSRRGLIRVTTQRAL----GQPPPPEPTASS-MASAPASSPPANATAPPLRW 460
PP+ PS+S QR L PP P P S + P+ PP PP R
Sbjct: 318 PPPL-PPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDPPGRS 376
Query: 461 GPL 463
GPL
Sbjct: 377 GPL 379
Score = 35.8 bits (81), Expect = 0.20
Identities = 57/221 (25%), Positives = 73/221 (33%), Gaps = 60/221 (27%)
Query: 156 PTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQG-----PPHT 210
P P+R L +++ P L G+ G PP S PP D G PP
Sbjct: 332 PRLPQRNLSLSSSTPPLPSPGRSGPLPP--------PPSERPPPPVRDPPGRSGPLPPPP 383
Query: 211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYS-QEPGAQ 269
VS +G+ R + PA P + S V+ S P
Sbjct: 384 PVSRNGSTSRAL------------------------PATPQLPSRSGVDSPRSGPRPPLP 419
Query: 270 PDLALARSLPPAEELPVETPKRAG-----AEVSWEVSSPGPPPKQADLPDAKDSPGPQPT 324
PD A + PP P T R G E WE P +DLP
Sbjct: 420 PDRPSAGAPPPP---PPSTSIRNGFQDSPCEDEWESRFYFHP--ISDLP----------- 463
Query: 325 DPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPK 365
PP S P + A N + S +R RGA P P+
Sbjct: 464 -PPEPYVQTTKSYPSKLARNESRSGSNRRERGAPPLPPIPR 503
Score = 34.3 bits (77), Expect = 0.59
Identities = 68/268 (25%), Positives = 81/268 (30%), Gaps = 54/268 (20%)
Query: 729 VPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGRGPQGGPGL 788
VP P + P N G+ P G PS G RG G G
Sbjct: 187 VPSTPRPIQSSPHNRGS------------PPVPGGPRQPSPGPTPPPFPGNRGTALGGGS 234
Query: 789 SRNGVGPAPSLSELDLRPPSPINLSRSID--------AALFREHLVRDSV---------- 830
R P S S RPP P SR++D R + R++V
Sbjct: 235 IRQS--PLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKP 292
Query: 831 ----FQRCGLRGLASPPPGGALRPRRGSHPKAELDDAGSSLLRGRCRSLSDVRV------ 880
R A PPP RP P + + + L R SLS
Sbjct: 293 PVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPG 352
Query: 881 -RGPVPQHVVEAPDGAAAAASGSS-----------LDSFSRGSLKISWNPWRHGLSSVDS 928
GP+P E P G S S SR P R G+ S S
Sbjct: 353 RSGPLPPPPSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATPQLPSRSGVDSPRS 412
Query: 929 LPLDELPSTVQLLPAPTPAPDSTAARQG 956
P LP AP P P ST+ R G
Sbjct: 413 GPRPPLPPDRPSAGAPPPPPPSTSIRNG 440
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 62.4 bits (150), Expect = 2e-09
Identities = 108/464 (23%), Positives = 158/464 (34%), Gaps = 76/464 (16%)
Query: 32 RPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMP--EKPVA 89
RPLE S + P P S E F E+P + + +PA E P P A
Sbjct: 487 RPLEESPLSPPPEESPL-SPPPESSPFSPLEESPLSPPEESPP---SPALETPLSPPPEA 542
Query: 90 SPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELL---QQEAVAPHP 146
SPL P + P ++L + P + + P + + ++ ++P P
Sbjct: 543 SPLSPPF--------EESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEESPMSPPP 594
Query: 147 VGH---PHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSD 203
P P +P + + PP E PP D + PP S
Sbjct: 595 EASRLFPPFEESPLSPPPEESPLSPPP----EASRLSPPPEDSPMS-------PPPEESP 643
Query: 204 HQGPPH-TLVSHSGTVKR---PVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVE 259
PP + +S V R P E + P ++ P D + PP E
Sbjct: 644 MSPPPEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPE 703
Query: 260 VVYSQEPGAQPDLALARSLP-------PAEELPVETPKRAGAEVSWEVSSP--GPPPKQA 310
P + P SLP P E P P+ G +S P P P++
Sbjct: 704 ----DSPASPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEP 759
Query: 311 DLPDAKDSP--GPQPTDPPASEAPDRPSKPERAAMNGADP------ISPQRVRGAVEAPG 362
L + P PQP +P P+ P +A P +SPQ +
Sbjct: 760 HLSPQAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVP 819
Query: 363 TPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPG--------RPQSHPPAPPVQAPST 414
L P P + + ++E P + +P+E+ P RP+ PP P Q P+
Sbjct: 820 EEPCLSPQPEESHLSP-QSEEPCLSPRPEESHLSPELEKPPLSPRPEK-PPEEPGQCPAP 877
Query: 415 SRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPL 458
L PPP EP+ S + PA S P PL
Sbjct: 878 EELPLF----------PPPGEPSLSPLLGEPALSEPGEPPLSPL 911
Score = 62.0 bits (149), Expect = 3e-09
Identities = 107/445 (24%), Positives = 160/445 (35%), Gaps = 81/445 (18%)
Query: 18 PLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH 77
PL G L PL N E+P++P P+ S S P + P +P ++ R S
Sbjct: 418 PLGKAGVQLEPQLEAPL-NEEMPLLPP--PEESPLSPPP--EESPTSPPPEASRLSP--- 469
Query: 78 APAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELL 137
P EE+P ASPL AL+ + + + P ++ ++ P S ++ PL+ L
Sbjct: 470 -PPEELP----ASPLPEALHLSRPLEESPLS--PPPEESPLSPPPESSPFS-PLEESPLS 521
Query: 138 QQEAVAPHPVGHPHLT----FIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTK 193
E P P L+ P +P + + PP +E P E +
Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPP------EELPTSPPPEASRLSPP 575
Query: 194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVG 253
P SP + P P E F + P ++ P +P
Sbjct: 576 PEESPMSPPPEESP-----------MSPPPEASRLFPPFEESPLSPP--PEESPLSP--- 619
Query: 254 SVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWE-VSSPGPPPKQADL 312
PP S P P PP EE P+ P VS PPP+++ L
Sbjct: 620 --PPEASRLSPPPEDSP------MSPPPEESPMSPPPEVSRLSPLPVVSRLSPPPEESPL 671
Query: 313 -PDAKDSPGPQPTD-----PPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKS 366
P ++SP P + PP ++P P + P SP + P
Sbjct: 672 SPPPEESPTSPPPEASRLSPPPEDSPTSPPPED-------SPASPPPEDSLMSLPLEESP 724
Query: 367 LIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQR 426
L+P P +P R+E P + +P+E P RP+ +P + P S
Sbjct: 725 LLPLPEEP-QLCPRSEGPHLSPRPEEPHLSP-RPEEPHLSPQAEEPHLS----------- 771
Query: 427 ALGQPPPPEPTASSMASAPASSPPA 451
P P EP ++ P SP A
Sbjct: 772 ----PQPEEPCLCAVPEEPHLSPQA 792
Score = 52.0 bits (123), Expect = 3e-06
Identities = 73/288 (25%), Positives = 102/288 (35%), Gaps = 54/288 (18%)
Query: 182 PPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQ-GGFE---EHLQEAA 237
PP E KA + + S GPP+ G V P GG E + +A
Sbjct: 2276 PPFGESRKALEVKKEELGASSPSYGPPNL-----GFVDSPSSGTHLGGLELKTPDVFKAP 2330
Query: 238 QGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVS 297
P +Q +P +P +G P QEP PPA+ L P
Sbjct: 2331 LTPRASQVEPQSPGLGLRP-------QEP------------PPAQALAPSPPSHP----- 2366
Query: 298 WEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGA 357
++ PG P A+ P+P PP P + + P SPQ + +
Sbjct: 2367 -DIFRPGSYTD----PYAQPPLTPRPQPPPPESCCALPPRSLPSDPFSRVPASPQS-QSS 2420
Query: 358 VEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPS---- 413
++P TP+ L P P R +SP +P P RPQS P P+ P
Sbjct: 2421 SQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRP------PSRPQSRDPFAPLHKPPRPQP 2474
Query: 414 ---TSRRGLIRVTTQRALGQPP--PPEPTASSMASAPASSPPANATAP 456
+ G + T+ A G P P P A P+ PP +P
Sbjct: 2475 PEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFVRSP 2522
Score = 50.8 bits (120), Expect = 6e-06
Identities = 119/509 (23%), Positives = 175/509 (34%), Gaps = 87/509 (17%)
Query: 24 PALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEM 83
P R FP P E S + P P + P+A + P P DS + +P
Sbjct: 594 PEASRLFP-PFEESPLSPPPEESP---LSPPPEASRLSP--PPEDSPMSPPPEESPMSPP 647
Query: 84 PE---------------KPVASPLGPALYGPKAAQGAQRERL----------PVTDDLQM 118
PE P SPL P + + RL P +D
Sbjct: 648 PEVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPA 707
Query: 119 AQGPSSHGWTGPLDSQELL---QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHE 175
+ P + PL+ LL ++ + P G PHL+ P P R P L +
Sbjct: 708 SPPPEDSLMSLPLEESPLLPLPEEPQLCPRSEG-PHLSPRPEEPHLSPRPEE--PHLSPQ 764
Query: 176 GQEGQWPPRDEG---LKAKTKSRVPPTSPSDHQGP--------PHTLVSHSGTV-KRPVL 223
+E P+ E + + P + H P P T H V + P L
Sbjct: 765 AEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCL 824
Query: 224 EGQGGFEEHLQEAAQGPHFT---QQDPAAPDVGSVP--PVEVVYSQEPGAQPDLALARSL 278
Q E HL ++ P + ++ +P++ P P +EPG P
Sbjct: 825 SPQPE-ESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPGQCPAPEELPLF 883
Query: 279 PPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKP 338
PP E P + +S PG PP + SP +P+ P PD P
Sbjct: 884 PPPGE-----PSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPP 938
Query: 339 ERAAMNGADP--ISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGA--LQPDEAE 394
+ A P +SP G +E P K G SDP ESP+ A L+ +
Sbjct: 939 LSPIITAAAPPALSP---LGELEYPFGAK----GDSDP-------ESPLAAPILETPISP 984
Query: 395 EWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMAS-APASSPPANA 453
P PP+ P + G L +P PP+ + S P +SPP+
Sbjct: 985 PPEANCTDPEPVPPMILPPSP--GSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPSQC 1042
Query: 454 TAP------PLRWGPLRRVLSFSWELHVY 476
+ P P P+ +V+ S E ++
Sbjct: 1043 SPPALPLSVPSPLSPIGKVVGVSDEAELH 1071
Score = 42.7 bits (99), Expect = 0.002
Identities = 86/398 (21%), Positives = 123/398 (30%), Gaps = 75/398 (18%)
Query: 83 MPEKPVASPLGPALYGPKAA-QGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEA 141
MP KP+ P GP G ++ + + +GPS+H GPL + A
Sbjct: 4001 MPAKPLQHFSSPGALGPTLLLTGKEQNTVDPAVSSEATEGPSTHQG-GPLAIGTTPESMA 4059
Query: 142 VAPHPV-----GHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRV 196
P V G L + P+ Q + P L+ GQ+ Q + ++
Sbjct: 4060 TEPGEVKPSLSGDSQLLLVQPQPQPQPSSLQLQPPLRLPGQQQQQVSLLHTAGGGSHGQL 4119
Query: 197 PPTSPSDHQGPPHTLVSHS-------GTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAA 249
S S+ PH L S G++ + +L Q E + GP + P
Sbjct: 4120 GSGSSSEASSVPHLLAQPSVSLGDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVL 4179
Query: 250 ------PDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSP 303
P VG +P V + +Q G R L P ++ +
Sbjct: 4180 QSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQL----------------- 4222
Query: 304 GPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGT 363
QA L + P + P + P + G PQ G
Sbjct: 4223 -----QALLMQRQLQQSQAVRQTPPYQEPGTQTSP----LQGLLGCQPQLGGFPGPQTGP 4273
Query: 364 PKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVT 423
+ L GP GP R +P GAL P HP PP
Sbjct: 4274 LQELGAGPRPQGPP--RLPAPPGALSTG-----PVLGPVHPTPPPSS------------- 4313
Query: 424 TQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWG 461
P EP S +P+S P A PP G
Sbjct: 4314 ---------PQEPKRPSQLPSPSSQLPTEAQLPPTHPG 4342
Score = 38.9 bits (89), Expect = 0.024
Identities = 97/384 (25%), Positives = 137/384 (35%), Gaps = 93/384 (24%)
Query: 33 PLENSEIPMIPGAHPKG--SVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVAS 90
P +SE P H G ++G+ P++ P + +S + + P+ P +
Sbjct: 4031 PAVSSEATEGPSTHQGGPLAIGTTPESMATEPGEVKPSLSGDSQLLLVQPQPQPQ-PSSL 4089
Query: 91 PLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQE------LLQQEAVA- 143
L P L P G Q++++ L G SHG G S E LL Q +V+
Sbjct: 4090 QLQPPLRLP----GQQQQQV----SLLHTAGGGSHGQLGSGSSSEASSVPHLLAQPSVSL 4141
Query: 144 ---------------------------------PHPV-----GHPHLTFIPTTP--RRQL 163
P PV G P + +PT R QL
Sbjct: 4142 GDQPGSMTQNLLGPQQPMLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQL 4201
Query: 164 R-VATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPV 222
+ V P L+H P + + L+A R S + Q PP+ GT P
Sbjct: 4202 QGVLAKNPQLRHLS-----PQQQQQLQALLMQRQLQQSQAVRQTPPY---QEPGTQTSP- 4252
Query: 223 LEGQ-------GGFEEH----LQEAAQGPH--FTQQDPAAPDVGSVPPV--EVVYSQEPG 267
L+G GGF LQE GP + PA P S PV V + P
Sbjct: 4253 LQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPS 4312
Query: 268 AQPDLALARSLP-PAEELPVET---PKRAGAEVSWEVSSPGPP----PKQADLPDAKDSP 319
+ + LP P+ +LP E P G + PP P A L D S
Sbjct: 4313 SPQEPKRPSQLPSPSSQLPTEAQLPPTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSK 4372
Query: 320 GPQPTDPPASEAPDRPSKPERAAM 343
G P DPP + A KPE++++
Sbjct: 4373 GLGPWDPPDNLA--ETQKPEQSSL 4394
Score = 37.7 bits (86), Expect = 0.053
Identities = 58/212 (27%), Positives = 76/212 (35%), Gaps = 45/212 (21%)
Query: 270 PDLALARSLPPAEELPV-ETPKRAGAEVSWEVSSPGP--------PPKQADLPDAKDSPG 320
PD L P + L V E+P G + S + SP P K+ +L + S G
Sbjct: 2241 PDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKALEVKKEELGASSPSYG 2300
Query: 321 PQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNR 380
P P D PS + G + +P +AP TP++ P PG +
Sbjct: 2301 P-----PNLGFVDSPSSGTH--LGGLELKTPD----VFKAPLTPRASQVEPQSPGLGLRP 2349
Query: 381 TESPMG-ALQPDEAEEWPGRPQSHPPA----PPVQAPSTSRRGLIRVTTQRALGQPPPPE 435
E P AL P P P P P Q P T R QPPPPE
Sbjct: 2350 QEPPPAQALAPSP----PSHPDIFRPGSYTDPYAQPPLTPRP------------QPPPPE 2393
Query: 436 PTAS----SMASAPASSPPANATAPPLRWGPL 463
+ S+ S P S PA+ + PL
Sbjct: 2394 SCCALPPRSLPSDPFSRVPASPQSQSSSQSPL 2425
Score = 36.6 bits (83), Expect = 0.12
Identities = 53/219 (24%), Positives = 77/219 (35%), Gaps = 44/219 (20%)
Query: 250 PDVGSVPPVE--VVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPP 307
P+ G P E +Y G QP S+ P E P++ + + ++ P
Sbjct: 375 PEPGDTPTDEPDALYVACQG-QPKGGHVTSMQPKEPGPLQCEAKPLGKAGVQLEPQLEAP 433
Query: 308 KQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSL 367
++P P P PP E+P P PE A +SP P+ L
Sbjct: 434 LNEEMP-LLPPPEESPLSPPPEESPTSPP-PE------ASRLSPP-----------PEEL 474
Query: 368 IPGPSDPGPAVNRT--ESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQ 425
P ++R ESP+ P E P+S P +P ++P +
Sbjct: 475 PASPLPEALHLSRPLEESPLSP--PPEESPLSPPPESSPFSPLEESPLS----------- 521
Query: 426 RALGQPPPPEPTASSMASAPASSPP-ANATAPPLRWGPL 463
PP E S P S PP A+ +PP PL
Sbjct: 522 ------PPEESPPSPALETPLSPPPEASPLSPPFEESPL 554
Score = 36.6 bits (83), Expect = 0.12
Identities = 108/438 (24%), Positives = 149/438 (34%), Gaps = 63/438 (14%)
Query: 34 LENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH------APAEEMPEKP 87
L+N +P PG G SEP + P +S + +V+ +P+ P
Sbjct: 2252 LDNLAVPESPGVG--GGKASEP----LLSPPPFGESRKALEVKKEELGASSPSYGPPNLG 2305
Query: 88 -VASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHP 146
V SP G + + P+T + P S G L QE +A+AP P
Sbjct: 2306 FVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVE-PQSPGLG--LRPQEPPPAQALAPSP 2362
Query: 147 VGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEG--QWPPRDEGLKAKTKSRVP--PTSPS 202
HP + F P + + P Q E PPR L + SRVP P S S
Sbjct: 2363 PSHPDI-FRPGSYTDPYAQPPLTPRPQPPPPESCCALPPRS--LPSDPFSRVPASPQSQS 2419
Query: 203 DHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVY 262
Q P RP+ E + P F DP S PP
Sbjct: 2420 SSQSP---------LTPRPLSA------EAFCPSPVTPRFQSPDPY-----SRPP----- 2454
Query: 263 SQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQ 322
S+ P L + P P E +AG+ + + G P A LP G
Sbjct: 2455 SRPQSRDPFAPLHK---PPRPQPPEVAFKAGSLAHTSLGAGGFP---AALPAGP--AGEL 2506
Query: 323 PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTP--KSLIPGPSDPGP-AVN 379
P+ + P+ P A G SP R +A G P K +P P P P +N
Sbjct: 2507 HAKVPSGQPPNFVRSPGTGAFVGTP--SPMRFTFP-QAVGEPSLKPPVPQPGLPPPHGIN 2563
Query: 380 RTESPMGAL-QPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTA 438
P L +P HP P+ S S ++ R PPP P
Sbjct: 2564 SHFGPGPTLGKPQSTNYTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDG 2623
Query: 439 SSMASAPASSPPANATAP 456
S + +S + T+P
Sbjct: 2624 SLPYLSHGASQRSGITSP 2641
Score = 35.8 bits (81), Expect = 0.20
Identities = 65/260 (25%), Positives = 101/260 (38%), Gaps = 44/260 (16%)
Query: 234 QEAAQGPH-----FTQQDPA-APDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE 287
+EA + PH + Q+D A +P + +P + P +P AL +P +LPV
Sbjct: 4717 EEAPRFPHLGSGRWEQEDRALSPVIPLIPRASIPVF--PDTKPYGALGLEVPG--KLPVT 4772
Query: 288 T-PKRAGAEVSWEVSSPGPPPKQ--------ADLPDAK----------DSPGPQPTDPPA 328
T K G+EVS ++ K A+L K +SP T+P
Sbjct: 4773 TWEKGKGSEVSVMLTVSAAAAKNLNGVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKK 4832
Query: 329 SEAPDRPSKPERAAMNGADPISPQRVR--GAVEAPGTPKSLIP--------GPSDPGPAV 378
EA + P E+ + P ++ AV T KS + P+ P
Sbjct: 4833 GEA-EGPGGKEKGLEGKSPDTGPDWLKQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQ 4891
Query: 379 NRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAP-STSRRGLIRVTTQRALGQPPPPEPT 437
+ + L + P S PP+P +P S L+ + T+ L +PP P P
Sbjct: 4892 HSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPASPPTEPLVELPTE-PLAEPPVPSP- 4949
Query: 438 ASSMASAPASSPPANATAPP 457
+AS+P S+ P PP
Sbjct: 4950 -LPLASSPESARPKPRARPP 4968
Score = 33.9 bits (76), Expect = 0.77
Identities = 58/281 (20%), Positives = 84/281 (29%), Gaps = 50/281 (17%)
Query: 202 SDHQGPPHTLVSHSG-----TVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVP 256
S G P + + SG T P EG+G + Q + Q ++D + ++
Sbjct: 1963 SPEPGEPDSPWTGSGGTTPSTPTTPTTEGEGDGLSYNQRSLQR---WEKDEELGQLSTIS 2019
Query: 257 PVEVVYSQEPGAQPD-----------LALARSLPPAEELPV-------ETPKRAGAEVSW 298
PV P + D + L R +P A++ P R
Sbjct: 2020 PVLYANINFPNLKQDYPDWSSRCKQIMKLWRKVPAADKAPYLQKAKDNRAAHRINKVQKQ 2079
Query: 299 EVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAV 358
S K D+ D P PP A P + P +P + +
Sbjct: 2080 AESQINKQTKVGDIARKTDRPALHLRIPPQPGALGSPPPAAAPTIFIGSPTTPAGLSTSA 2139
Query: 359 EA-PGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRR 417
+ P +PGP PG + PP P Q PS
Sbjct: 2140 DGFLKPPAGSVPGPDSPGELFLKL----------------------PPQVPAQVPSQDPF 2177
Query: 418 GLIRV-TTQRALGQPPPPEPTASSMASAPASSPPANATAPP 457
GL + PP P S APA P A++ P
Sbjct: 2178 GLAPAYPLEPRFPTAPPTYPPYPSPTGAPAQPPMLGASSRP 2218
Score = 32.7 bits (73), Expect = 1.7
Identities = 53/209 (25%), Positives = 71/209 (33%), Gaps = 44/209 (21%)
Query: 291 RAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPIS 350
R+ AE V S PP+ PG PTD P + +P+ + P
Sbjct: 359 RSVAEQHTPVCSRFSPPE----------PGDTPTDEPDALYVACQGQPKGGHVTSMQPKE 408
Query: 351 PQ--------------RVRGAVEAP-GTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEE 395
P ++ +EAP L+P P + + ESP P EA
Sbjct: 409 PGPLQCEAKPLGKAGVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSP--PPEASR 466
Query: 396 WPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPP-------PE-----PTASSMAS 443
P+ P +P +A SR + L PP PE P S S
Sbjct: 467 LSPPPEELPASPLPEALHLSRP-----LEESPLSPPPEESPLSPPPESSPFSPLEESPLS 521
Query: 444 APASSPPANATAPPLRWGPLRRVLSFSWE 472
P SPP+ A PL P LS +E
Sbjct: 522 PPEESPPSPALETPLSPPPEASPLSPPFE 550
Score = 31.6 bits (70), Expect = 3.8
Identities = 50/190 (26%), Positives = 68/190 (35%), Gaps = 39/190 (20%)
Query: 159 PRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTV 218
P R T P + EG G +++GL+ K+ P T P L +
Sbjct: 4820 PESPARAGTEPKKGEAEGPGG----KEKGLEGKS----PDTGPD-------WLKQFDAVL 4864
Query: 219 KRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVG-------SVPPVEVVYSQEPGAQPD 271
L+ Q L++ + P Q +V S PP E EP P
Sbjct: 4865 PGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPE-----EPSPPPS 4919
Query: 272 -LALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASE 330
LA + + PP E L VE P AE P P L + +S P+P P E
Sbjct: 4920 PLAPSPASPPTEPL-VELPTEPLAEP--------PVPSPLPLASSPESARPKPRARPPEE 4970
Query: 331 APDRPSKPER 340
D S+P R
Sbjct: 4971 GED--SRPPR 4978
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 1124
Score = 62.0 bits (149), Expect = 3e-09
Identities = 130/514 (25%), Positives = 183/514 (35%), Gaps = 94/514 (18%)
Query: 17 LPLLGTGPALGRGFPRPLEN-------SEIP-MIPGAHPKGSVGSEPQAFDVFPENPRAD 68
L +LG A+GR +PL + IP P A P S G+ + P +
Sbjct: 44 LRVLGAAGAVGR---KPLAERAGGIGGATIPESAPRAGPTRSAGTSSRN----PASRPPA 96
Query: 69 SHRNSDVRHAPAEEMPEKPVASP---LGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSH 125
S R R PA+ PV+SP G GP +G L ++ + +A+G ++
Sbjct: 97 SGRGE--RAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG-----LRISAEETVARGKATE 149
Query: 126 GWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRD 185
S +++ P P G P P RR R A L + P
Sbjct: 150 APKRSALSAGA-RRDTSGPTP-GTPS----PAMARRS-RAAGTEVGLPRPAPSARPRPPT 202
Query: 186 EGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQ 245
EG + K+ S S ++ S G ++RP L A+ +
Sbjct: 203 EGPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARG 261
Query: 246 DPAAPDVGSVPPVEVVYSQEPG--AQPDLALARSLPPAEELPVETPKRAG---------- 293
P AP S P + + + P P A +L P P+ TP +G
Sbjct: 262 TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPD 321
Query: 294 -AEVSWEVSSPGPPPKQADLPDAKDSPG--------PQPTDPPASEAPDRPSKPERAAMN 344
A + P PP LP A SP P P P S+AP + P A
Sbjct: 322 NAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPP 381
Query: 345 GADPISPQRV-----RGAVEAPGTP---KSLIPGPSDPGPAVNRTES--PMGALQPDEAE 394
I P +V +++AP +P SL S P + T S M Q +
Sbjct: 382 SLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASL 441
Query: 395 EWPGRPQSHPP-APPVQAP---------STSRRGLIRVTTQ-------RALG-------Q 430
P RP S PP +PP+QAP TS + + +AL Q
Sbjct: 442 TSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSPQ 501
Query: 431 PP------PPEPTASSMASAPASSPPANATAPPL 458
P PP T SS+A +PPA+ T PPL
Sbjct: 502 APLSSLIMPPLETQSSLAPPSLQTPPASLTTPPL 535
Score = 59.7 bits (143), Expect = 1e-08
Identities = 91/377 (24%), Positives = 126/377 (33%), Gaps = 58/377 (15%)
Query: 88 VASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPV 147
+ SP PA P + LP + LQ + P+ + PL L ++A H
Sbjct: 441 LTSPSRPASTPPDSPPLQAPLSLPASPPLQTSLSPAVSPLSSPLTIHPLQALSSLASHSP 500
Query: 148 GHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGP 207
P + I P + + + PPSLQ PP + +P +P P
Sbjct: 501 QAPLSSLI--MPPLETQSSLAPPSLQTPPASLTTPPLEN---------LPSLAP-----P 544
Query: 208 PHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPG 267
P L + S + P LE +A P T P P + PP P
Sbjct: 545 P--LQTASAPLTTPHLETPPCPAPCPLQAPPSP-LTTPPPETPSSIATPP--------PQ 593
Query: 268 AQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPP 327
A P LA PP + LP S +S PP QA P PP
Sbjct: 594 APPALAS----PPLQGLP-----------SPPLSPLATPPPQAP---------PXLALPP 629
Query: 328 ASEAPDRPSKPERAAMNGADPISPQRVR-GAVEAPGTPKSLIPGPSDPGPAVNRTESPMG 386
P P+ P + + P +P + ++AP +P P + P + SP
Sbjct: 630 LQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSA 689
Query: 387 ALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPA 446
P PP+PP P + T PP P S PA
Sbjct: 690 TPPSQAPPSLAAPPLQVPPSPPASPPMSPS------ATPPPQAPPPLAAPPLQVPPSPPA 743
Query: 447 SSPPANATAPPLRWGPL 463
S P + + PP R PL
Sbjct: 744 SPPMSPSATPPPRVPPL 760
Score = 59.3 bits (142), Expect = 2e-08
Identities = 92/429 (21%), Positives = 140/429 (32%), Gaps = 37/429 (8%)
Query: 42 IPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKA 101
+P S + P + +P+A + + AP P PV +P P P +
Sbjct: 627 LPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVS 686
Query: 102 AQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRR 161
+ P + Q P S + P+ + P P P L P
Sbjct: 687 PSATPPSQAPPSLAAPPLQVPPSPPASPPMSP-------SATPPPQAPPPLAAPP----- 734
Query: 162 QLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRP 221
L+V PP+ PPR L A +VPP+ P+ P + +P
Sbjct: 735 -LQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSP---------LAKP 784
Query: 222 VLEGQGGFEEHLQEAAQGP--HFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLP 279
+ +A P F Q P +P P+ + + P A P LA
Sbjct: 785 PPQAPPALATPPLQALPSPPASFPGQAPFSPSASL--PMSPLATPPPQAPPVLAA----- 837
Query: 280 PAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPE 339
P ++P P + +PGP + P + P P PP+ S P+
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSG-PRLTLALAPGPPPPPSRSPSSTLSGPD 896
Query: 340 RAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGR 399
A + + +P+ +RG P + P P A + G P PG
Sbjct: 897 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 956
Query: 400 PQSHPPAP-PVQAPST----SRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANAT 454
P PPA P A G T P P T+ A+A A + ++ +
Sbjct: 957 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 1016
Query: 455 APPLRWGPL 463
R G L
Sbjct: 1017 PKQARLGEL 1025
Score = 57.0 bits (136), Expect = 8e-08
Identities = 120/459 (26%), Positives = 158/459 (34%), Gaps = 99/459 (21%)
Query: 24 PALGRGFPRP----LENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAP 79
P+ G G RP L +S P+ A S P+A P +P + P
Sbjct: 228 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA----PAHPSQPKPKGLQALRPP 283
Query: 80 AEEMPEKPVASPLGPALYGPKAA---QGAQRERLPVTDDLQM---AQGPSSHGWTGPLDS 133
P K A LGP P A G + +P D+ A P S PL
Sbjct: 284 QVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAATPLPATLPPSPPLATPLP- 342
Query: 134 QELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTK 193
P P P L +P+ P PPS Q PP +
Sbjct: 343 -------LAPPSPSAPPSLQTLPSPP-------ATPPS--------QAPP--------SM 372
Query: 194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVG 253
+ P +P Q P V HS T P L+ A P A +G
Sbjct: 373 TTPPMQAPPSLQTIPPIQVPHSLT--SPSLQ-----------APPSPLALSSLQATTSLG 419
Query: 254 SVPPVEVVYS---QEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQA 310
S P ++ +S P Q +L PA P P +A +S P PP Q
Sbjct: 420 S-PTLQATHSFLTMSP-RQTQASLTSPSRPASTPPDSPPLQA------PLSLPASPPLQT 471
Query: 311 DLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPG--TPKSLI 368
L SP P P + P + A++ SPQ ++ P T SL
Sbjct: 472 SL-----SPAVSPLSSPLTIHPLQ-------ALSSLASHSPQAPLSSLIMPPLETQSSLA 519
Query: 369 PGPSDPGPAVNRTESPMGALQ-----PDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVT 423
P PS P + T P+ L P + P H PP AP + +T
Sbjct: 520 P-PSLQTPPASLTTPPLENLPSLAPPPLQTASAP-LTTPHLETPPCPAPCPLQAPPSPLT 577
Query: 424 TQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
T PPPE T SS+A+ P +PPA A +PPL+ P
Sbjct: 578 T-------PPPE-TPSSIATPPPQAPPALA-SPPLQGLP 607
Score = 55.1 bits (131), Expect = 3e-07
Identities = 85/359 (23%), Positives = 120/359 (33%), Gaps = 72/359 (20%)
Query: 166 ATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSH---------SG 216
AT+P S G P R G ++ + PP S + PP S SG
Sbjct: 68 ATIPESAPRAG-----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 217 TVKRPVLEGQGGFEEHLQE------AAQGPHFT------QQDPAAPDVGSVPPVEVVYSQ 264
T RP GQ G +E A + P + ++D + P G+ P S+
Sbjct: 123 TT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 265 EPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKD------- 317
G + + L R P A P R + E S+ P P P A
Sbjct: 182 AAGTE--VGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 318 ---SPGPQPTDPPASE---------APDRPSKPERAAMNGADP--ISPQRVRGAVEAPGT 363
S P PA AP PS+P+ + P ++P R A
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPL 299
Query: 364 PKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAP-STSRRGLIRV 422
S + PS G P A P P + PP+PP+ P +
Sbjct: 300 SSSPLATPSPSGTKARPVPPPDNAATP--------LPATLPPSPPLATPLPLAPPSPSAP 351
Query: 423 TTQRALGQPP--PPEPTASSMASAPASSPPA-----------NATAPPLRWGPLRRVLS 468
+ + L PP PP SM + P +PP+ + T+P L+ P LS
Sbjct: 352 PSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALS 410
>gi|38373671 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 61.2 bits (147), Expect = 4e-09
Identities = 80/280 (28%), Positives = 104/280 (37%), Gaps = 38/280 (13%)
Query: 195 RVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQ-GPHFTQQDPAAPDVG 253
+ PP S + PP + + T + P GQ + + Q Q GP T Q P G
Sbjct: 53 QTPPQGMS--RAPPSSGAPPASTAQAPC--GQAAYGQFGQGDVQNGPSSTVQMQRLP--G 106
Query: 254 SVP---PVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSP------- 303
S P P+ V +Q P QP PP V T + +G ++S V+
Sbjct: 107 SQPFGSPLAPVGNQPPVLQP------YGPPPTSAQVAT-QLSGMQISGAVAPAPPSSGLG 159
Query: 304 -GPPPKQADLPDAKDSPG-----PQPTDPPASEAPDRPS--KPERAAMNGADPISPQRVR 355
GPP A + + G PQ PP S+A P P+R+A + A +P
Sbjct: 160 FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPP-AS 218
Query: 356 GAVEAPGTPKSLIPGPSDPGPAV---NRTESPMGALQPDEAEEWP--GRPQSHPPAPPVQ 410
G P L+PG S GP+V N SP AL P P P H P P
Sbjct: 219 GGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGY 278
Query: 411 APSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPP 450
P + Q G P P PT S P PP
Sbjct: 279 QPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318
>gi|38373669 SEC24-related protein C [Homo sapiens]
Length = 1094
Score = 61.2 bits (147), Expect = 4e-09
Identities = 80/280 (28%), Positives = 104/280 (37%), Gaps = 38/280 (13%)
Query: 195 RVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQ-GPHFTQQDPAAPDVG 253
+ PP S + PP + + T + P GQ + + Q Q GP T Q P G
Sbjct: 53 QTPPQGMS--RAPPSSGAPPASTAQAPC--GQAAYGQFGQGDVQNGPSSTVQMQRLP--G 106
Query: 254 SVP---PVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSP------- 303
S P P+ V +Q P QP PP V T + +G ++S V+
Sbjct: 107 SQPFGSPLAPVGNQPPVLQP------YGPPPTSAQVAT-QLSGMQISGAVAPAPPSSGLG 159
Query: 304 -GPPPKQADLPDAKDSPG-----PQPTDPPASEAPDRPS--KPERAAMNGADPISPQRVR 355
GPP A + + G PQ PP S+A P P+R+A + A +P
Sbjct: 160 FGPPTSLASASGSFPNSGLYGSYPQGQAPPLSQAQGHPGIQTPQRSAPSQASSFTPP-AS 218
Query: 356 GAVEAPGTPKSLIPGPSDPGPAV---NRTESPMGALQPDEAEEWP--GRPQSHPPAPPVQ 410
G P L+PG S GP+V N SP AL P P P H P P
Sbjct: 219 GGPRLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGY 278
Query: 411 APSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPP 450
P + Q G P P PT S P PP
Sbjct: 279 QPQQNGSFGPARGPQSNYGGPYPAAPTFGSQPGPPQPLPP 318
>gi|120587025 SH3 and multiple ankyrin repeat domains 1 [Homo sapiens]
Length = 2161
Score = 61.2 bits (147), Expect = 4e-09
Identities = 83/343 (24%), Positives = 109/343 (31%), Gaps = 38/343 (11%)
Query: 144 PHPVGHPHLTFIPTTPRRQLRVATVPPSLQ-HEGQEGQWPPRDEGLKAKTKSRVPPTSPS 202
P P+ HP LT P L +A E EG P+ + PP +P
Sbjct: 1335 PRPLVHP-LTGKALDPASPLGLALAARERALKESSEGGGAPQPPPRPPSPRYEAPPPTPH 1393
Query: 203 DHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD---PAAPDVGSVPPVE 259
H PH +H V R L G + +E Q+ PA+P +
Sbjct: 1394 HHS--PH---AHHEPVLR--LWGASPPDPARRELGYRAGLGSQEKSLPASPPAARRSLLH 1446
Query: 260 VVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVS----------WEVSSPGPPPKQ 309
+ PG P L + PPA V P R+ A E P P
Sbjct: 1447 RLPPTAPGVGPLLLQLGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFLENCQPRAPVTS 1506
Query: 310 ADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIP 369
P ++D PG P P S P P+ P + NG + +V+ +
Sbjct: 1507 GRGPPSEDGPGVPPPSPRRS-VPPSPTSPRASEENGLPLLVLPPPAPSVDVEDGEFLFVE 1565
Query: 370 GPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPS---------------T 414
P N E P L P P P P PPV P+ T
Sbjct: 1566 PLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPPTLDSTASSLT 1625
Query: 415 SRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPP 457
S + TQ A P P P +APA + P PP
Sbjct: 1626 SYDSEVATLTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPP 1668
Score = 49.7 bits (117), Expect = 1e-05
Identities = 98/397 (24%), Positives = 133/397 (33%), Gaps = 68/397 (17%)
Query: 77 HAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQEL 136
H A+ E+P P GP L + + GA + P P + ++ L +
Sbjct: 865 HHRAQPSYERPSFLPPGPGLMLRQKSIGAAEDDRPYL-------APPAMKFSRSLS---V 914
Query: 137 LQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRV 196
E + P P P P P V + L + G + P G +
Sbjct: 915 PGSEDIPPPPTTSP-----PEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGG-------PL 962
Query: 197 PPTSPSDHQGP--PHTLVS-------HSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDP 247
P +SP+ GP P T V HSG + P H Q H P
Sbjct: 963 PASSPASFDGPSPPDTRVGSREKSLYHSGPLP-PAHHHPPHHHHHHAPPPQPHHHHAHPP 1021
Query: 248 AAPDV---GSV--PPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSS 302
P++ GS PP + G QP L R P+ +P G+ SS
Sbjct: 1022 HPPEMETGGSPDDPPPRLAL----GPQPSLRGWRGGGPSPTPGAPSPSHHGSAGGGGGSS 1077
Query: 303 PGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPG 362
GP + LP S A P R + + + + +V G + G
Sbjct: 1078 QGPALRYFQLPPRAASA--------AMYVPARSGRGRKGPL-----VKQTKVEGEPQKGG 1124
Query: 363 TPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHP-PAPPVQAPSTSRRGLIR 421
L P PS PA SP QP A P S P P ++APSTS G
Sbjct: 1125 ---GLPPAPSPTSPA-----SP----QPPPAVAAPSEKNSIPIPTIIIKAPSTSSSGRSS 1172
Query: 422 VTTQRALGQPPPPEPTASSMASAPASSP-PANATAPP 457
+ P PEPT + SP PA + PP
Sbjct: 1173 QGSSTEAEPPTQPEPTGGGGGGGSSPSPAPAMSPVPP 1209
Score = 48.1 bits (113), Expect = 4e-05
Identities = 123/507 (24%), Positives = 167/507 (32%), Gaps = 138/507 (27%)
Query: 62 PENPRADSHRNSDVRHAPAEEMPEKPV-----ASPLGPAL--YGPKAAQGAQRERLPVTD 114
P +PR ++ + H+P +PV ASP PA G +A G+Q + LP +
Sbjct: 1380 PPSPRYEAPPPTPHHHSPHAH--HEPVLRLWGASPPDPARRELGYRAGLGSQEKSLPASP 1437
Query: 115 DLQ----MAQGPSSHGWTGPLDSQELLQQEAVAPHP-VGHPHLTFIPTTPRRQLRVATVP 169
+ + P + GPL Q L E APHP V P + P P R
Sbjct: 1438 PAARRSLLHRLPPTAPGVGPLLLQ--LGTEPPAPHPGVSKPWRSAAPEEPERLPLHVRFL 1495
Query: 170 PSLQHEGQ--EGQWPPRDEGLKAKTKS---RVPP--TSP--SDHQGPPHTLV---SHSGT 217
+ Q G+ PP ++G S VPP TSP S+ G P ++ + S
Sbjct: 1496 ENCQPRAPVTSGRGPPSEDGPGVPPPSPRRSVPPSPTSPRASEENGLPLLVLPPPAPSVD 1555
Query: 218 VKR----------PVLEGQGGFEEHLQEAAQGPHFTQQDPAAP--DVGSVPPVEVV---- 261
V+ P LE FE+ GP D AP + VPP V
Sbjct: 1556 VEDGEFLFVEPLPPPLEFSNSFEKPESPLTPGPPHPLPDTPAPATPLPPVPPPAVAAAPP 1615
Query: 262 -----------YSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPP--- 307
Y E L S P + P P A + P PPP
Sbjct: 1616 TLDSTASSLTSYDSEVAT---LTQGASAAPGDPHPPGPPAPAAPAPAAPQPGPDPPPGTD 1672
Query: 308 ---KQADLPDAKDSP---------------------------------GPQPTDP----- 326
++ D + D P GP+ D
Sbjct: 1673 SGIEEVDSRSSSDHPLETISSASTLSSLSAEGGGSAGGGGGAGAGVASGPELLDTYVAYL 1732
Query: 327 -----PASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPS----DPGPA 377
S P P P+ ++P ++RG A G L PGPS DP
Sbjct: 1733 DGQAFGGSSTPGPPYPPQL--------MTPSKLRG--RALGASGGLRPGPSGGLRDPVTP 1782
Query: 378 VNRTESPMGA-----------LQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQR 426
+ T S GA P A G P PPV P+ S + +
Sbjct: 1783 TSPTVSVTGAGTDGLLALRACSGPPTAGVAGGPVAVEPEVPPVPLPTASSLPRKLLPWEE 1842
Query: 427 ALGQPPPP------EPTASSMASAPAS 447
G PPPP +P AS++A+ AS
Sbjct: 1843 GPGPPPPPLPGPLAQPQASALATVKAS 1869
Score = 41.6 bits (96), Expect = 0.004
Identities = 84/347 (24%), Positives = 115/347 (33%), Gaps = 60/347 (17%)
Query: 72 NSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPL 131
+ D+ P PE P ++P P+ G P + A P+S P
Sbjct: 917 SEDIPPPPTTSPPEPPYSTPPVPSSSGRLTPSPRGGPFNPGSGGPLPASSPASFDGPSPP 976
Query: 132 DSQ------ELLQQEAVAP---HPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWP 182
D++ L + P HP H H P P PP ++ G P
Sbjct: 977 DTRVGSREKSLYHSGPLPPAHHHPPHHHHHHAPPPQPHHHHAHPPHPPEMETGGSPDDPP 1036
Query: 183 PRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGP-- 240
PR + PS G P SH G+ G GG ++QGP
Sbjct: 1037 PRLALGPQPSLRGWRGGGPSPTPGAPSP--SHHGSAG-----GGGG-------SSQGPAL 1082
Query: 241 HFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE-TPKRAG----AE 295
+ Q P A P R P ++ VE P++ G A
Sbjct: 1083 RYFQLPPRAASAAMYVPARS------------GRGRKGPLVKQTKVEGEPQKGGGLPPAP 1130
Query: 296 VSWEVSSPGPPPKQADLPDAKDSPGPQPT---DPPASEAPDR-----------PSKPERA 341
+SP PPP A P K+S P PT P++ + R P++PE
Sbjct: 1131 SPTSPASPQPPPAVA-APSEKNSI-PIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQPEPT 1188
Query: 342 AMNGADPISPQRVRGAVEAPGTPKSLIPGPSDP-GPAVNRTESPMGA 387
G SP P +P S +P P+ P GPA S GA
Sbjct: 1189 GGGGGGGSSPSPAPAMSPVPPSP-SPVPTPASPSGPATLDFTSQFGA 1234
Score = 35.4 bits (80), Expect = 0.26
Identities = 26/89 (29%), Positives = 38/89 (42%), Gaps = 5/89 (5%)
Query: 721 PAPSGKSEVPERPNNCYAGPSNVGAGSLDISKSLIRNPAESGQLATPSSGAWGSAASLGR 780
PAPS S +P A PS S+ I +I+ P+ S + + +
Sbjct: 1128 PAPSPTSPASPQPPPAVAAPSE--KNSIPIPTIIIKAPSTSSSGRSSQGSSTEAEPPTQP 1185
Query: 781 GPQGGPGLSRNGVGPAPSLSELDLRPPSP 809
P GG G + PAP++S + PPSP
Sbjct: 1186 EPTGGGGGGGSSPSPAPAMSPV---PPSP 1211
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 59.7 bits (143), Expect = 1e-08
Identities = 89/409 (21%), Positives = 147/409 (35%), Gaps = 62/409 (15%)
Query: 74 DVRHAPAEEM--PEKPVASPLGPALYGPKAAQGAQRERLPVTDDL---QMAQGPSSHGWT 128
+ + PAEE PEK SP+ P A+ ++E ++ + A+ P+
Sbjct: 500 ETKSPPAEEAASPEKEAKSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAK 559
Query: 129 GPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGL 188
P +++ ++EA +P V P P + P
Sbjct: 560 SPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPE----------------- 602
Query: 189 KAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPA 248
KAK+ + SP++ + P VK P E A+ P T+++
Sbjct: 603 KAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP-------------EKAKSP--TKEEAK 647
Query: 249 APDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE----TPKRAGAEVSWEVSSP- 303
+P+ P E S E P A A+S P + PV+ +P++A + V E SP
Sbjct: 648 SPEKAKSPEKEEAKSPEKAKSPVKAEAKS-PEKAKSPVKAEAKSPEKAKSPVKEEAKSPE 706
Query: 304 ---------GPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSK---PERAAMNGADPISP 351
P++A P +++ P+ P E P K PE+A D SP
Sbjct: 707 KAKSPVKEEAKSPEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKA--KTLDVKSP 764
Query: 352 QRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQP-DEAEEWPGR--PQSHPPAPP 408
+ A E +P P + P +SP A P E + P + P+ P
Sbjct: 765 EAKTPAKEEARSPADKFPEKA-KSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSP 823
Query: 409 VQAPSTSRRGLIRVTTQRALGQPPPPEP-TASSMASAPASSPPANATAP 456
V+ + ++ ++A + P P T S +P A P
Sbjct: 824 VKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKP 872
Score = 40.4 bits (93), Expect = 0.008
Identities = 53/232 (22%), Positives = 87/232 (37%), Gaps = 31/232 (13%)
Query: 224 EGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEE 283
E +GG EE EA G T+ PP E S E A+ + P +
Sbjct: 485 EEEGGEEE---EAEGGEEETKS----------PPAEEAASPEKEAKSPVKEEAKSPAEAK 531
Query: 284 LPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPAS-EAPDRPSKP-ERA 341
P + ++ AEV + P ++A P SP + PA ++P++ P +
Sbjct: 532 SPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEE 591
Query: 342 AMNGADPISPQRVRGAV----EAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWP 397
A + A+ SP++ + V ++P KS P +SP P++A+ P
Sbjct: 592 AKSPAEAKSPEKAKSPVKEEAKSPAEAKS---------PVKEEAKSPAEVKSPEKAKS-P 641
Query: 398 GRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSP 449
+ ++ P ++P + PE A S A A SP
Sbjct: 642 TKEEAKSP-EKAKSPEKEEAKSPEKAKSPVKAEAKSPE-KAKSPVKAEAKSP 691
>gi|54860079 nadrin isoform 1 [Homo sapiens]
Length = 881
Score = 59.7 bits (143), Expect = 1e-08
Identities = 89/331 (26%), Positives = 124/331 (37%), Gaps = 46/331 (13%)
Query: 165 VATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLE 224
VA + P +QH W +E +++ VP T+PS + S SGT++R
Sbjct: 428 VAVIEPIIQH----ADWFFPEEVEFNVSEAFVPLTTPSSNHSFHTGNDSDSGTLERKRPA 483
Query: 225 GQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEEL 284
E L + A G++ + P QP L
Sbjct: 484 SMAVMEGDLVKKESFGVKLMDFQAHRRGGTLNRKHI----SPAFQPPLPPTDGSTVVPAG 539
Query: 285 PVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPG----PQPTDPPASEAP-------- 332
P P+ + AE S S G P A + + SPG P+P DP ++ P
Sbjct: 540 PEPPPQSSRAESS---SGGGTVPSSAGILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQ 596
Query: 333 --DRPSKPERAA----------MNGADPISPQRVRGAVE--APGTPKSLIPGPSDPG-PA 377
++P+ AA N A P SP +R AV+ AP PK P P PG +
Sbjct: 597 IASGQNQPQAAAGSHQLSMGQPHNAAGP-SPHTLRRAVKKPAPAPPKPGNPPPGHPGGQS 655
Query: 378 VNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQ--APS---TSRRGLIRVTTQRALGQPP 432
+ T +L P P P H PP Q APS RR ++ +A PP
Sbjct: 656 SSGTSQHPPSLSPKPPTRSPSPPTQHTGQPPGQPSAPSQLSAPRRYSSSLSPIQAPNHPP 715
Query: 433 PPEPTASS--MASAPASSPPANATAPPLRWG 461
P PT ++ M + P S P N A P G
Sbjct: 716 PQPPTQATPLMHTKPNSQGPPNPMALPSEHG 746
Score = 40.4 bits (93), Expect = 0.008
Identities = 75/306 (24%), Positives = 98/306 (32%), Gaps = 66/306 (21%)
Query: 167 TVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSP----------SDHQGPPHTLVSHSG 216
TVP S G Q P +G K K V P S P SH
Sbjct: 557 TVPSSA---GILEQGPSPGDGSPPKPKDPVSAAVPAPGRNNSQIASGQNQPQAAAGSHQL 613
Query: 217 TVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALAR 276
++ +P G L+ A + P PA P G+ PP PG Q ++
Sbjct: 614 SMGQPH-NAAGPSPHTLRRAVKKPA-----PAPPKPGNPPP------GHPGGQSSSGTSQ 661
Query: 277 SLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPS 336
P P P R SP PP + P PG QP+ P AP R S
Sbjct: 662 HPPSLSPKP---PTR----------SPSPPTQHTGQP-----PG-QPSAPSQLSAPRRYS 702
Query: 337 KPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDP----GPAVNRTESPMGALQPDE 392
+SP ++AP P P + P P +PM AL +
Sbjct: 703 SS----------LSP------IQAPNHPPPQPPTQATPLMHTKPNSQGPPNPM-ALPSEH 745
Query: 393 AEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSM-ASAPASSPPA 451
E P P PP P + + A G P +P A ++ P P
Sbjct: 746 GLEQPSHTPPQTPTPPSTPPLGKQNPSLPAPQTLAGGNPETAQPHAGTLPRPRPVPKPRN 805
Query: 452 NATAPP 457
+ PP
Sbjct: 806 RPSVPP 811
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 59.3 bits (142), Expect = 2e-08
Identities = 108/386 (27%), Positives = 133/386 (34%), Gaps = 57/386 (14%)
Query: 71 RNSDVRHAPAEEMPEKPVA-SPLGPALYGPKA----AQGAQRERLPVTDDLQMAQGPSSH 125
R +VR A A + V+ SP G A GP A A GA E P G +
Sbjct: 46 RTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPPA--------GRARP 97
Query: 126 GWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRD 185
G GP Q P P P + P P +LR PP EG G P
Sbjct: 98 GGGGP--------QRPGPPSP-RRPLVPAGPAPPAAKLR----PPP---EGSAGSCAPVP 141
Query: 186 EGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQ 245
P P+ GP L + +G P G G + A G T
Sbjct: 142 AAAAVAAGPEPAPAGPAKPAGPA-ALAARAGPGPGPG-PGPGPGPGPGKPAGPGAAQTLN 199
Query: 246 DPAA---PDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSS 302
AA + P V +V + P L P A ++TP GA ++
Sbjct: 200 GSAALLNSHHAAAPAVSLVNNG-----PAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAA 254
Query: 303 PGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPG 362
P PP A A P P P + P P+ P AA P + Q A AP
Sbjct: 255 PSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPA 314
Query: 363 TPKSLIPGPSDPGPA-VNRTESP---MGALQPDEAEEWPGR-PQSHPPAPPVQA----PS 413
P P+ GPA V+ P A P E P R Q+ PPA A S
Sbjct: 315 ------PAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAS 368
Query: 414 TSRRGLIRVTTQRALGQP---PPPEP 436
T+ +I T Q AL P PPP P
Sbjct: 369 TAASMVIGPTMQGALPSPAAVPPPAP 394
Score = 53.9 bits (128), Expect = 7e-07
Identities = 66/243 (27%), Positives = 88/243 (36%), Gaps = 20/243 (8%)
Query: 234 QEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAG 293
Q AA H P P+V + + G+ A A PAE P P+
Sbjct: 32 QLAASAAHHHHLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAGPAAPAEGAPGAAPEPPP 91
Query: 294 AEVSWEVSS----PGPPPKQADL-------PDAKDSPGPQPTD---PPASEAPDRPSKPE 339
A + PGPP + L P AK P P+ + P A + PE
Sbjct: 92 AGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPE 151
Query: 340 RAAMNGADPISPQRVR---GAVEAPGTPKSLIPGPSDP-GPAVNRTESPMGALQPDEAEE 395
A A P P + G PG PGP P GP +T + AL
Sbjct: 152 PAPAGPAKPAGPAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAA 211
Query: 396 WPGRPQ-SHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANAT 454
P ++ PA + P + G + + T +G PP P A S +APA + PA A
Sbjct: 212 APAVSLVNNGPAALLPLPKPAAPGTV-IQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAP 270
Query: 455 APP 457
PP
Sbjct: 271 PPP 273
Score = 46.6 bits (109), Expect = 1e-04
Identities = 95/377 (25%), Positives = 129/377 (34%), Gaps = 68/377 (18%)
Query: 247 PAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPP 306
PA P PP E P A A E P K AG + PGP
Sbjct: 119 PAPPAAKLRPPPE---GSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPG 175
Query: 307 PKQADLPDAKDSPGP-QPTDPPASEAPD---------RPSKPERAAMNGAD----PISPQ 352
P P PGP +P P A++ + + P + +N P+
Sbjct: 176 PG----PGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKP 231
Query: 353 RVRGAV---------EAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSH 403
G V AP P + P P+ P PA P P A RP H
Sbjct: 232 AAPGTVIQTPPFVGAAAPPAPAAPSP-PAAPAPAAPAAAPP----PPPPAPATLARPPGH 286
Query: 404 PPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTA---SSMASAPASSPPANATAPPLRW 460
P PP AP+ + + G P P P A + ++ P A A AP ++
Sbjct: 287 PAGPPTAAPAVPPPAAAQ--NGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKA 344
Query: 461 GPLRRVLSFSWELHVYGVGVLFLLPALLALAALAAAPAGPRLALVAAVLVL---VASALR 517
+RV+ + PA LAA +GP A AA +V+ + AL
Sbjct: 345 ESPKRVVQAA-------------PPAAQTLAA-----SGP--ASTAASMVIGPTMQGALP 384
Query: 518 SAYMLTDPY-GSQARL--GVRGGLV--LYNLPFPLLLTALAALTLLGLGAGLPPPLQNPL 572
S + P G+ L G G + L P A LT L LP P QNP
Sbjct: 385 SPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQPPQNPT 444
Query: 573 LLGAVALVHGVGLLATD 589
+ L G+ L+ ++
Sbjct: 445 NIQNFQLPPGMVLVRSE 461
Score = 37.7 bits (86), Expect = 0.053
Identities = 107/450 (23%), Positives = 142/450 (31%), Gaps = 79/450 (17%)
Query: 18 PLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH 77
PL+ GPA RP +V + P+ P P + +
Sbjct: 113 PLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGP 172
Query: 78 APAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELL 137
P P P PA GP AAQ + +SH P S
Sbjct: 173 GPGPGPGPGPGPGPGKPA--GPGAAQTLNGSAALL----------NSHHAAAPAVSLVNN 220
Query: 138 QQEAVAPHPVGHPHLTFIPTTP-----RRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKT 192
A+ P P T I T P A PP+ PP A T
Sbjct: 221 GPAALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPA-T 279
Query: 193 KSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDV 252
+R PP P+ GPP + + V P GG AA P AP
Sbjct: 280 LAR-PPGHPA---GPP----TAAPAVPPPAAAQNGGSAG----AAPAP--------APAA 319
Query: 253 GSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKR---AGAEVSWEVSSPGPPPKQ 309
G V S +PG P A A PA + E+PKR A + +++ GP
Sbjct: 320 GGPAGV----SGQPG--PGAAAAA---PAPGVKAESPKRVVQAAPPAAQTLAASGPASTA 370
Query: 310 ADL---PDAKDS-PGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPK 365
A + P + + P P PPA P K A+ + +P + A TP
Sbjct: 371 ASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTPT 430
Query: 366 SLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQ 425
L P P P N T L PP S G + + Q
Sbjct: 431 VL--APRLPQPPQNPTNIQNFQL------------------PPGMVLVRSENGQLLMIPQ 470
Query: 426 RALGQ-----PPPPEPTASSMASAPASSPP 450
+AL Q P+ T + + P S+PP
Sbjct: 471 QALAQMQAQAHAQPQTTMAPRPATPTSAPP 500
Score = 35.8 bits (81), Expect = 0.20
Identities = 102/481 (21%), Positives = 156/481 (32%), Gaps = 94/481 (19%)
Query: 45 AHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKP-VASPLGPALYGPKAAQ 103
A P G P A P A + ++ APA V+ GP A
Sbjct: 281 ARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAAAAAPAP 340
Query: 104 GAQRER-------LPVTDDLQMAQGPSSHGWT---GPLDSQELLQQEAVAPHPVGHP--- 150
G + E P A GP+S + GP L AV P G P
Sbjct: 341 GVKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAAVPPPAPGTPTGL 400
Query: 151 ----------HLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTS 200
L+ PT +R P L + PP++ PT+
Sbjct: 401 PKGAAGAVTQSLSRTPTATTSGIRATLTPTVLAPRLPQ---PPQN------------PTN 445
Query: 201 PSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEV 260
+ Q PP ++ S + ++ Q + Q AQ PA P S PPV++
Sbjct: 446 IQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQTTMAPRPATPT--SAPPVQI 503
Query: 261 VYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVS-SPGPPPK----------- 308
Q PG +AR + P + + + + S + SPG P+
Sbjct: 504 STVQAPGTP---IIARQVTPTTIIKQVSQAQTTVQPSATLQRSPGVQPQLVLGGAAQTAS 560
Query: 309 -------QADLPDAKDSPGPQPTDPPASEAPDRPSKPER--AAMNGADPISPQRVRGAVE 359
Q P + PG T A+E + K + + + Q A
Sbjct: 561 LGTATAVQTGTPQ-RTVPGATTTSSAATETMENVKKCKNFLSTLIKLASSGKQSTETAAN 619
Query: 360 APGTPKSLIPGP---------------SDPG----PAVNRTESPMGALQPDEAEEWPGRP 400
++L+ G S P P + R+ + L PD A + +
Sbjct: 620 VKELVQNLLDGKIEAEDFTSRLYRELNSSPQPYLVPFLKRSLPALRQLTPDSA-AFIQQS 678
Query: 401 QSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRW 460
Q PP P QA + ++ + QR G+ TA+++ S A PP + P +
Sbjct: 679 QQQPPPPTSQATTALTAVVLSSSVQRTAGK------TAATVTS--ALQPPVLSLTQPTQV 730
Query: 461 G 461
G
Sbjct: 731 G 731
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 58.9 bits (141), Expect = 2e-08
Identities = 114/471 (24%), Positives = 162/471 (34%), Gaps = 66/471 (14%)
Query: 29 GFPRPLENSEIPMIPGA----HPKGSVGSEPQAFDV-------FPEN-PRADSHRNS--- 73
G PRP P+ P A G+VG +P A PE+ PRA R S
Sbjct: 31 GSPRPPP----PVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86
Query: 74 ----DVRHAPAEEMPEKPVASP---LGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHG 126
R PA+ PV+SP G GP +G L ++ + +A+G ++
Sbjct: 87 ASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLGQKG-----LRISAEETVARGKATEA 141
Query: 127 WTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDE 186
S +++ P P G P P RR R A L + P E
Sbjct: 142 PKRSALSAGA-RRDTSGPTP-GTPS----PAMARRS-RAAGTEVGLPRPAPSARPRPPTE 194
Query: 187 GLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD 246
G + K+ S S ++ S G ++RP L A+ +
Sbjct: 195 GPR-KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGT 253
Query: 247 PAAPDVGSVPPVEVVYSQEPG--AQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPG 304
P AP S P + + + P P A +L P P+ TP + SP
Sbjct: 254 PRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPP------SPS 307
Query: 305 PPPKQADLPDAKDSPGPQPTDP---PASEAPDR--PSKPERAAMNGADPISPQRVRGAVE 359
PP LP +P Q T P +A PS P P ++
Sbjct: 308 APPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQ 367
Query: 360 APGTPKSLIP-----GPSDPGP---AVNRTESPMGALQPDEAEEWPGRPQSHPPA----- 406
AP +P + P PS P AV+ ++P P + P P + PP
Sbjct: 368 APPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSAT 426
Query: 407 PPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPP 457
PP QAP + ++V P P T A P ++PP PP
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 477
Score = 50.8 bits (120), Expect = 6e-06
Identities = 79/281 (28%), Positives = 107/281 (38%), Gaps = 33/281 (11%)
Query: 197 PPTSPSDHQGPPHT-----LVSHSGTV-KRPVLEGQGGFE-EHLQEAAQ--GPHFTQQDP 247
PP SP PP T ++ +G V ++P+ E GG + E+A GP T + P
Sbjct: 29 PPGSP--RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRTSRPP 86
Query: 248 AAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPV-ETPKRAGAEVSWEVSSPGPP 306
A+ PP + S P + P A + P P+ + R AE +
Sbjct: 87 ASGRGERAPPAKNT-SPGPVSSPGRASGTTRPG----PLGQKGLRISAEETVARGKATEA 141
Query: 307 PKQADLPDA--KDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTP 364
PK++ L +D+ GP P P S A R S+ + P R R E P
Sbjct: 142 PKRSALSAGARRDTSGPTPGTP--SPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKS 199
Query: 365 KSLIPGPS--DPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRV 422
S S +P PA R S G LQ P A P+ +P+ R G
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQR------PASRSLSSSATPLSSPA--RSGPSAR 251
Query: 423 TTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPL 463
T RA P P+P P +PP AP L GPL
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--GPL 290
Score = 50.8 bits (120), Expect = 6e-06
Identities = 115/506 (22%), Positives = 155/506 (30%), Gaps = 73/506 (14%)
Query: 24 PALGRGFPRP----LENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAP 79
P+ G G RP L +S P+ A S P+A P +P + P
Sbjct: 219 PSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRA----PAHPSQPKPKGLQALRPP 274
Query: 80 AEEMPEKPVASPLGPALYGPKAAQGAQRERLP-VTDDLQMAQGP---------------- 122
P K A LGP P A P LQ P
Sbjct: 275 QVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPT 334
Query: 123 --SSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQ------- 173
++H + L AP + P L P+ P PS Q
Sbjct: 335 LQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAV 394
Query: 174 HEGQEGQWPPRDEGLKAK-TKSRVPPTSPS---DHQGPPHTL-----VSHSGTVKRPVLE 224
H Q PP ++A + PP SPS Q PP V S P+
Sbjct: 395 HLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 454
Query: 225 GQGGFEEHLQEAAQGP-HFTQQDPAAPDVGSVPPVEVVYSQE---PGAQPDLALARSLPP 280
+ A P + P AP + PP++ + S PG P + + SLP
Sbjct: 455 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAP-FSPSASLPM 513
Query: 281 ---AEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQ--------------- 322
A P P A + S P P QA P +PGP
Sbjct: 514 SPLATPPPQAPPVLAAPLLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPG 571
Query: 323 PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTE 382
P PP+ S P+ A + + +P+ +RG P + P P A +
Sbjct: 572 PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAA 631
Query: 383 SPMGALQPDEAEEWPGRPQSHPPAP-PVQAPST----SRRGLIRVTTQRALGQPPPPEPT 437
G P PG P PPA P A G T P P T
Sbjct: 632 WSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGT 691
Query: 438 ASSMASAPASSPPANATAPPLRWGPL 463
+ A+A A + ++ + R G L
Sbjct: 692 SGGKAAAGAGAGASSRSPKQARLGEL 717
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 58.5 bits (140), Expect = 3e-08
Identities = 86/366 (23%), Positives = 115/366 (31%), Gaps = 89/366 (24%)
Query: 166 ATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVS---------HSG 216
AT+P S G P R G ++ + PP S + PP S SG
Sbjct: 68 ATIPESAPRAG-----PTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG 122
Query: 217 TVKRPVLEGQGGFEEHLQE------AAQGPHFT------QQDPAAPDVGSVPPVEVVYSQ 264
T RP GQ G +E A + P + ++D + P G+ P S+
Sbjct: 123 TT-RPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSR 181
Query: 265 EPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDS------ 318
G ++ L R P A P R + E S+ P P P A
Sbjct: 182 AAGT--EVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPAS 239
Query: 319 ----------PGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLI 368
P + P A P P+ P + G + P + V P +
Sbjct: 240 RSLSSSATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQ----VTPPRKDAAPA 295
Query: 369 PGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHP------------------------ 404
GP P T SP ALQ P P S
Sbjct: 296 LGPLSSSPLA--TPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQT 353
Query: 405 -PAPPVQAPSTSRRGLIRVTTQRA-----------LGQPPPPEPTASSMASAPASSPPAN 452
P+PP PS + L T Q L PPP P A +A P +PP+
Sbjct: 354 LPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPA--LALPPLQAPPSP 411
Query: 453 ATAPPL 458
+PPL
Sbjct: 412 PASPPL 417
Score = 54.3 bits (129), Expect = 5e-07
Identities = 56/229 (24%), Positives = 82/229 (35%), Gaps = 24/229 (10%)
Query: 236 AAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAE 295
A P Q A P + + P + Q P + S PP+ + P ++
Sbjct: 305 ATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQ 364
Query: 296 VSWEVSSPGPPPKQADLPDAKDSP--GPQPTDPPASEAPDRPSKPERAAMNGADPISPQR 353
+ + SP + LP SP P P PPA P + P A + P+SP
Sbjct: 365 ATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPA---SPPLSPL- 420
Query: 354 VRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPA-----PP 408
A +P P +L AV+ ++P P + P P + PP PP
Sbjct: 421 ---ATPSPQAPNAL---------AVHLLQAPFSP-PPSPPVQAPFSPPASPPVSPSATPP 467
Query: 409 VQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPP 457
QAP + ++V P P T A P ++PP PP
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPP 516
Score = 50.1 bits (118), Expect = 1e-05
Identities = 116/489 (23%), Positives = 154/489 (31%), Gaps = 63/489 (12%)
Query: 18 PLLGTGPALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRH 77
P PALG PL +S P A P S + QA P P + S
Sbjct: 288 PRKDAAPALG-----PLSSS-----PLATPSPSAALQSQAPPTLPATPHSSSLTCQLATP 337
Query: 78 APAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELL 137
P P P A P L P A +Q T L ++H + L
Sbjct: 338 LPLA--PPSPSAPPSLQTLPSPPATPPSQ-----ATTSLGSPTLQATHSFLPSPPLSPLA 390
Query: 138 QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQ-------HEGQEGQWPPRDEGLKA 190
AP + P L P+ P PS Q H Q PP ++A
Sbjct: 391 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQA 450
Query: 191 K-TKSRVPPTSPS---DHQGPPHTL-----VSHSGTVKRPVLEGQGGFEEHLQEAAQGP- 240
+ PP SPS Q PP V S P+ + A P
Sbjct: 451 PFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 510
Query: 241 HFTQQDPAAPDVGSVPPVEVVYSQE---PGAQPDLALARSLPP---AEELPVETPKRAGA 294
+ P AP + PP++ + S PG P + + SLP A P P A
Sbjct: 511 QLAKPPPQAPPALATPPLQALPSPPASFPGQAP-FSPSASLPMSPLATPPPQAPPVLAAP 569
Query: 295 EVSWEVSSPGPPPKQADLPDAKDSPGPQ---------------PTDPPASEAPDRPSKPE 339
+ S P P QA P +PGP P PP+ S P+
Sbjct: 570 LLQVPPSPPASPTLQA--PRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPD 627
Query: 340 RAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGR 399
A + + +P+ +RG P + P P A + G P PG
Sbjct: 628 LAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGA 687
Query: 400 PQSHPPAP-PVQAPST----SRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANAT 454
P PPA P A G T P P T+ A+A A + ++ +
Sbjct: 688 PLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRS 747
Query: 455 APPLRWGPL 463
R G L
Sbjct: 748 PKQARLGEL 756
Score = 46.2 bits (108), Expect = 1e-04
Identities = 79/302 (26%), Positives = 105/302 (34%), Gaps = 66/302 (21%)
Query: 197 PPTSPSDHQGPPHT-----LVSHSGTV-KRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAP 250
PP SP PP T ++ +G V ++P+ E GG G + P A
Sbjct: 29 PPGSP--RPPPPVTPAALRVLGAAGAVGRKPLAERAGGIG--------GATIPESAPRAG 78
Query: 251 DVGSVPPVEVVYSQEPGAQPDLA-LARSLPPAEEL---PVETPKRAGAEVSWEVSSPGP- 305
S S+ P ++P + PPA+ PV +P RA + PGP
Sbjct: 79 PTRSAG----TSSRNPASRPPASGRGERAPPAKNTSPGPVSSPGRASG-----TTRPGPL 129
Query: 306 --------------------PPKQADLPDA--KDSPGPQPTDPPASEAPDRPSKPERAAM 343
PK++ L +D+ GP P P S A R S+ +
Sbjct: 130 GQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTP--SPAMARRSRAAGTEV 187
Query: 344 NGADPISPQRVRGAVEAPGTPKSLIPGPS--DPGPAVNRTESPMGALQPDEAEEWPGRPQ 401
P R R E P S S +P PA R S G LQ P
Sbjct: 188 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQR------PASRS 241
Query: 402 SHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWG 461
A P+ +P+ R G T RA P P+P P +PP AP L G
Sbjct: 242 LSSSATPLSSPA--RSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPAL--G 297
Query: 462 PL 463
PL
Sbjct: 298 PL 299
>gi|40353727 synaptopodin isoform A [Homo sapiens]
Length = 903
Score = 58.5 bits (140), Expect = 3e-08
Identities = 86/331 (25%), Positives = 124/331 (37%), Gaps = 25/331 (7%)
Query: 71 RNSDVRHAPAEEMPEKPVASPLG-PALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTG 129
R + P + P V SP+ PA P+AA A+ L + +L P S
Sbjct: 556 RPEPTKQPPYQLRPSLFVLSPIKEPAKVSPRAASPAKPSSLDLVPNLPKGALPPSPALPR 615
Query: 130 PLDSQELLQ----QEAVAPHPVGHPHLTFI-PTTPRRQLRVATVPPSLQHEGQEGQWPPR 184
P S L Q+++ P V P+ I P +P R A P + Q + R
Sbjct: 616 PSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPSR----AWSPRAKQ--APRPSFSTR 669
Query: 185 DEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKR-PVLEGQGGFEEHLQEAAQGPHFT 243
+ G++A+ + PTSP G S G V P G+G + P
Sbjct: 670 NAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGS------SMSSPPPLP 723
Query: 244 QQDPAAPDVG--SVPPVEV-VYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEV 300
P +P SV P+ ++ P Q LAR++ A +P+ AGAE
Sbjct: 724 PPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRPF 783
Query: 301 SSP-GPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE 359
S P PPP P PQP P ++ P P + A P S R +
Sbjct: 784 SPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLP 843
Query: 360 APGTPKSLIPGPSDPGPAVNRTESPMGALQP 390
AP P P+D +++ +S GA P
Sbjct: 844 APPRPFLYRRSPTDSDVSLDSEDS--GAKSP 872
Score = 49.3 bits (116), Expect = 2e-05
Identities = 51/223 (22%), Positives = 76/223 (34%), Gaps = 37/223 (16%)
Query: 277 SLPPAEELPVETPKRAGAEVSWEVSSPGP----PPKQADLPDAKDSPGPQPTDPPASEAP 332
+LPP+ LP + G S S P PP D+ S + P A +AP
Sbjct: 606 ALPPSPALPRPSRSSPGLYTSPGQDSLQPTAVSPPYGGDISPVSPS---RAWSPRAKQAP 662
Query: 333 DRPSKPERAAMNGAD-----PISPQRVRGAVEAPGTPKSLI-PGPSDPGPAVNRTESPMG 386
A + D P SP GA P + + PGP +PG + + P
Sbjct: 663 RPSFSTRNAGIEAQDRRESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPL 722
Query: 387 ALQPDEAEEW------PGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQ---------- 430
P + W P RP++ P Q + R +I +++
Sbjct: 723 PPPPPMSPSWSERSVSPLRPETEARPPSRQLQALLARNIINAARRKSASPRSAGAENPRP 782
Query: 431 --------PPPPEPTASSMASAPASSPPANATAPPLRWGPLRR 465
PPPP P +P + P +A P + P+ R
Sbjct: 783 FSPPRAPPPPPPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPR 825
Score = 46.2 bits (108), Expect = 1e-04
Identities = 44/176 (25%), Positives = 58/176 (32%), Gaps = 17/176 (9%)
Query: 282 EELPVETPKRAGAEV------SWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRP 335
E LP P GA W P P + + + P P P P SE P
Sbjct: 680 ESLPTSPPWTPGASRPPSSLDGWVSPGPWEPGRGSSMSSPPPLPPPPPMSPSWSERSVSP 739
Query: 336 SKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEE 395
+PE A + + R + A + P G R SP A P
Sbjct: 740 LRPETEARPPSRQLQALLARNIINAARRKSA---SPRSAGAENPRPFSPPRAPPPP---- 792
Query: 396 WPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPA 451
P PP P +++P +R G V P P P S ++P S PA
Sbjct: 793 ----PPPPPPPPRMRSPQPARPGSAAVPGAAFAPIPRSPLPAGPSSCTSPRSPLPA 844
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 58.5 bits (140), Expect = 3e-08
Identities = 74/284 (26%), Positives = 110/284 (38%), Gaps = 37/284 (13%)
Query: 182 PPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPH 241
PP+ + +++ P SP + P + S T+ P + Q F E L GP
Sbjct: 187 PPKSVPV-CESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETL-----GPP 240
Query: 242 FTQQDPAAPDVGSVPPVEVVYSQEPGAQPDL---ALARSLPPAEELPVETPK--RAGAEV 296
+ P +P + + P + P A P+ A S P + P E+P+ + V
Sbjct: 241 -SASSPESPVLAASPEP---WGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAV 296
Query: 297 SWEVSSPGPPPKQADL-PDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVR 355
S E P P P SP P ++P AS P +P+KP A +SP
Sbjct: 297 SPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKP-------APSVSP---- 345
Query: 356 GAVEAPGTP-KSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPP---VQA 411
P P S+ PGP P P+V+ ++ P + P P+S PP A
Sbjct: 346 ----GPWKPIPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPASPESWKSGPPELRKTA 401
Query: 412 PSTSRRGLIRV-TTQRALGQPPPP-EPTASSMASAPASSPPANA 453
P+ S V L +P PP P S A +P P+ +
Sbjct: 402 PTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSGS 445
Score = 43.5 bits (101), Expect = 0.001
Identities = 81/392 (20%), Positives = 140/392 (35%), Gaps = 61/392 (15%)
Query: 35 ENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRN-SDVRHAPAEEMPEKPVASPLG 93
E+ ++ +P P+ P++ NP+ + + P+ PE PV +
Sbjct: 195 ESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAA-S 253
Query: 94 PALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLT 153
P +GP A + + T T P + +P P
Sbjct: 254 PEPWGPSPAASPESRKSART--------------TSP-------EPRKPSPSESPEPWKP 292
Query: 154 FIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVP-PTSPSDHQGPPHTLV 212
F +P + V P G G P A + P +PS GP +
Sbjct: 293 FPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIP 352
Query: 213 SHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDL 272
S S +P + ++ P + PA+P+ P E + P P+
Sbjct: 353 SVSPGPWKPTPSVSSA---SWKSSSVSPSSWKSPPASPESWKSGPPE-LRKTAPTLSPE- 407
Query: 273 ALARSLPP-AEELPVETPKRAGAEVSWEVSSPGPPP---KQADLPDA-KDSPGPQPTDPP 327
+++PP + EL ++ G +S E+ SP P K + PD K SP + T P
Sbjct: 408 -HWKAVPPVSPEL-----RKPGPPLSPEIRSPAGSPELRKPSGSPDLWKLSPDQRKTSPA 461
Query: 328 ASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGA 387
+ + P+ ++++ G+ + + P P++ PGPS P +ESP A
Sbjct: 462 SLDFPE----SQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGP------SESPKAA 511
Query: 388 -----------LQPDEAEEWPGRPQSHPPAPP 408
+P + +P ++ PPA P
Sbjct: 512 SDIWKPVLSIDTEPRKPALFPEPAKTAPPASP 543
Score = 40.8 bits (94), Expect = 0.006
Identities = 42/160 (26%), Positives = 58/160 (36%), Gaps = 41/160 (25%)
Query: 317 DSPGPQPTDPPASEAPDRPSKPE-RAAMNGADPISPQRVRGAVEAPGTPKSL-------- 367
+SP P P P + P PE + + +P P +V +P PKS+
Sbjct: 144 ESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSKP----ASVSSPEPPKSVPVCESQKL 199
Query: 368 --IPGPSDPGPAVNRTESPMGAL---QPDEAEEWP---GRPQSHPPAPPVQAPSTSRRGL 419
+P P PA ES L +P + +P G P + P PV A S
Sbjct: 200 APVPSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAAS------ 253
Query: 420 IRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLR 459
PEP S A++P S A T+P R
Sbjct: 254 --------------PEPWGPSPAASPESRKSARTTSPEPR 279
>gi|150170670 piccolo isoform 2 [Homo sapiens]
Length = 4935
Score = 58.5 bits (140), Expect = 3e-08
Identities = 85/355 (23%), Positives = 127/355 (35%), Gaps = 53/355 (14%)
Query: 134 QELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTK 193
Q+++Q+E P + P L P P P Q G++ P + +G
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPI---------PKQQGPGRD---PLQQDGTPKSIS 240
Query: 194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD------- 246
S+ P S PP T G + P + + LQ A P Q D
Sbjct: 241 SQQPEKIKSQ---PPGTGKPIQGPTQTPQTDHA---KLPLQRDASRPQTKQADIVRGESV 294
Query: 247 -PAAPDVGSVPPVEVVYSQEPGAQPDLALAR---SLPPAEELPVETPKRAGAEVSWEVSS 302
P+ P P + + P QP ++ + PPA+ + P A+ V
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL---AQQPGTVKP 351
Query: 303 PGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSK-PERAAMNGADPISPQRVRGAVEAP 361
P PP P P P SE P P+ A +P + G + P
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 362 ----GTPKSLI--PGPSDPGPAVNRTESPMGALQPDEA---EEWPGRP---QSHPPAPPV 409
GTPK L PG P A T++P+ P + + PG+ Q+ P PP
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 410 QAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLR 464
Q P ++ Q +PPP +P ++ P S P + PP + GP +
Sbjct: 472 QLPGPAKPP----PQQPGPAKPPPQQPGSAK----PPSQQPGSTKPPPQQPGPAK 518
Score = 57.0 bits (136), Expect = 8e-08
Identities = 98/388 (25%), Positives = 133/388 (34%), Gaps = 89/388 (22%)
Query: 62 PENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQG 121
P+ +AD R V+ P+ P KP P+ G AQ E+ AQ
Sbjct: 281 PQTKQADIVRGESVK--PSLPSPSKP---PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ- 334
Query: 122 PSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQW 181
PS G T PL QQ PV P T P P + P Q G E
Sbjct: 335 PS--GLTKPL-----AQQPGTVKPPVQPPGTTKPPAQP-----LGPAKPPAQQTGSE--- 379
Query: 182 PPRDEGLKAKTKSRVPPT--SPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQG 239
P E K ++ P +P+ GP GT K P+ + G LQ A+
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK-PLAQQPG-----LQSPAKA 433
Query: 240 PHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWE 299
P T+ P G +P + PG + PP++
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQA----GPGKTSAQQTGPTKPPSQ----------------- 472
Query: 300 VSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE 359
+ P PP Q P P PP P +P A P S Q
Sbjct: 473 LPGPAKPPPQQ----------PGPAKPP----PQQP--------GSAKPPSQQ------- 503
Query: 360 APGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGL 419
PG+ K P P PGPA + P G+ +P + +P + P+P + S + +
Sbjct: 504 -PGSTK---PPPQQPGPAKPSPQQP-GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 420 IRVTTQRALGQPPPPEPTASSMASAPAS 447
+Q G+P P PT S A P S
Sbjct: 559 ----SQTGSGKPLQP-PTVSPSAKQPPS 581
Score = 53.5 bits (127), Expect = 9e-07
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 48/293 (16%)
Query: 202 SDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVV 261
SD + V++ + +G + LQ+ P QQ P + + +
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI 239
Query: 262 YSQEPGAQPDLALARSLPPAEELPVE----TPKRAGAEVSWEVSSPGPPPKQAD------ 311
SQ+P +S PP P++ TP+ A++ + + P KQAD
Sbjct: 240 SSQQPEK------IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293
Query: 312 ----LPDAKDSPGPQPT--DPPASEAPDRPSKPERAAMNGADPISPQRV-RGAVEAPGTP 364
LP P QPT PPA + S+P A P P + + + PGT
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA----KPPAQPSGLTKPLAQQPGTV 349
Query: 365 KSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAP------------PVQAP 412
K + P P P+G +P + +P S P P P Q P
Sbjct: 350 KPPVQPPGTTKPPA----QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 413 STSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSP---PANATAPPLRWGP 462
++ +V T + L Q P + A A P +P P P + GP
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAK--APGPTKTPVQQPGPGKIPAQQAGP 456
Score = 48.5 bits (114), Expect = 3e-05
Identities = 87/391 (22%), Positives = 120/391 (30%), Gaps = 62/391 (15%)
Query: 86 KPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPH 145
KP A PLGPA P A Q + PSS GP + L Q V
Sbjct: 360 KPPAQPLGPAK--PPAQQTGSEK-------------PSSEQ-PGP---KALAQPPGVGKT 400
Query: 146 PVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEG-LKAKTKSRVPPTSPSDH 204
P P P P Q +V T P Q G + P + G K + P P+
Sbjct: 401 PAQQPG----PAKPPTQ-QVGTPKPLAQQPGLQS--PAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 205 QGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQ 264
GP T +G K P +Q P + P P PP + ++
Sbjct: 454 AGPGKTSAQQTGPTKPP---------------SQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 265 EPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPT 324
P QP + PP + P + + PG A P Q T
Sbjct: 499 PPSQQPG---STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 325 DPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPG----PAVNR 380
P + +P +P + + P S + T + L+ P
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 381 TESPMGALQPD----EAEEW------PGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQ 430
T + P+ E +EW R AP +P + TT
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS 675
Query: 431 PPPPEPTASSMASAP---ASSPPANATAPPL 458
P P+ T+ +AP S P PPL
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Score = 46.6 bits (109), Expect = 1e-04
Identities = 92/411 (22%), Positives = 137/411 (33%), Gaps = 80/411 (19%)
Query: 111 PVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPP 170
PVT +++ T P Q + AP P P L PT A PP
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 171 SLQHEGQEGQWPPRDEGLKAKT-KSRVPPTSPSDHQ--GPPHTLVSHSGTVKRPVLEGQG 227
+ PP++ + ++ K+ V P + P LVS S +P +
Sbjct: 725 EADSLSKPA--PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782
Query: 228 GFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQP----DLALARSLPPAEE 283
+ +E P T D A P P E V + A P D + P+ E
Sbjct: 783 -VQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839
Query: 284 L-------PV---ETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPD 333
PV E PK+A ++S + + P PK + P PGP+PT P
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAK-PMPKGSPTP-----PGPRPTAGQTVPTPQ 893
Query: 334 RPSKPE----RAAMN--------GADPISPQR-VRGAV---------------------- 358
+ KP+ R ++N + P +PQ V G +
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 359 ----EAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPST 414
PG P P PS P P G P A+ P + ++ PA P
Sbjct: 954 PHSQSGPGAPMKQAPAPSQP-PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Query: 415 SRRGLIRVTTQRALGQPPPPEPTASSMASAP---------ASSPPANATAP 456
+ ++ T + PPP + S+ + P SP +T P
Sbjct: 1013 EQAPTVKRTETE---KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 44.3 bits (103), Expect = 6e-04
Identities = 112/522 (21%), Positives = 161/522 (30%), Gaps = 123/522 (23%)
Query: 24 PALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEM 83
PA G +PL + P P G+ ++P A + P P A + P+ E
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPAQQTGSEK----PSSEQ 385
Query: 84 PEKPVASPLGPALYGPKA-AQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAV 142
P GPKA AQ + P G PL Q LQ A
Sbjct: 386 P-------------GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 143 APHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPS 202
AP P TP +Q +P G K + P PS
Sbjct: 433 APGPT---------KTPVQQPGPGKIPAQQAGPG------------KTSAQQTGPTKPPS 471
Query: 203 DHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDV----GSVPPV 258
GP G K P + Q + P Q PA P + PP
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 259 EVVYSQEPGAQ---------------------------PDLALARSLPPAEELP------ 285
+ S +P AQ P ++ + PP++ LP
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591
Query: 286 -------VETPKRAGAEVSWEVSSP-------GPPPKQADLPD-------AKDSPGPQPT 324
+ P++A E + P P ++ + K + G
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 325 DPPASEAPDRPSKP--ERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTE 382
P+S P + P +A++ + P Q AP S P P P P V +
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 383 ---SPMG-ALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTA 438
SP A QP EA+ PAPP + S + V + QP +PT
Sbjct: 712 LHGSPSAKAKQPPEAD------SLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPTT 764
Query: 439 SSMASAPASSPP-----------ANATAPPLRWGPLRRVLSF 469
++S+ A++ P T PPL+ + SF
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Score = 37.4 bits (85), Expect = 0.069
Identities = 46/229 (20%), Positives = 78/229 (34%), Gaps = 42/229 (18%)
Query: 273 ALARSLPPAEELPVETPKRAGAEVSWEVSSPGP--PPKQADLPDAKDSPGPQPTDPPASE 330
A+++S P ++ +PK+ A +P P PP P SP + PP ++
Sbjct: 671 AVSKSSPQPQQT---SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727
Query: 331 A---------PDRPSKPERAAMNGADPISPQRVRGAVE----APGTPKSLIPGPSDPGPA 377
+ P PS+ ++A + P P+ V+ + + T K IP A
Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787
Query: 378 VNRTESPMGALQPDEAEEWP--------------GRPQSHPPAPPVQAPSTSRRGLIRV- 422
+T P+ ++ +P RP S PS+ +G +V
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 423 ---------TTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
Q + P +P + P P A T P + P
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Score = 36.6 bits (83), Expect = 0.12
Identities = 38/158 (24%), Positives = 57/158 (36%), Gaps = 12/158 (7%)
Query: 269 QPDLALARSLPPAEELPVETPKRAGAEVSWEVSS--PGPPPKQADLPDAKDSPGPQPTDP 326
+P L P LP + P+ S ++S+ P PPP P P P P P
Sbjct: 2371 KPASQLPSGSPSVSSLPAK-PRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Query: 327 PASEAPD-RPSK------PERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVN 379
P S P P K P A D ++ + + G P + I + P
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 380 RTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRR 417
+ P G + E P +P P Q P+T+++
Sbjct: 2490 PSSIPSGLVFTHRPE--PSKPPIAPKPVIPQLPTTTQK 2525
Score = 33.1 bits (74), Expect = 1.3
Identities = 37/159 (23%), Positives = 55/159 (34%), Gaps = 20/159 (12%)
Query: 211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQP 270
++ H ++ G G + Q P + D P+E+ YS A
Sbjct: 3549 IIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADS 3608
Query: 271 DLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASE 330
+ LA S P ++PK + +S SPG + A +P K P P P
Sbjct: 3609 TVQLAPS-------PPKSPKVLYSPIS--PLSPGKALESAFVPYEK--PLPDDISPQKVL 3657
Query: 331 APDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIP 369
PD P P SP+ + + PK L P
Sbjct: 3658 HPDMAKVP---------PASPKTAKMMQRSMSDPKPLSP 3687
Score = 32.3 bits (72), Expect = 2.2
Identities = 35/134 (26%), Positives = 50/134 (37%), Gaps = 16/134 (11%)
Query: 317 DSPGPQ---PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIP--GP 371
D+ PQ T PP + P + ++ AD V+ A P +PK L P
Sbjct: 3574 DTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRAD----STVQLAPSPPKSPKVLYSPISP 3629
Query: 372 SDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQP 431
PG A+ P PD+ PP +P T++ QR++ P
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA-SPKTAKM------MQRSMSDP 3682
Query: 432 PPPEPTASSMASAP 445
P PTA + AP
Sbjct: 3683 KPLSPTADESSRAP 3696
Score = 30.8 bits (68), Expect = 6.5
Identities = 68/321 (21%), Positives = 111/321 (34%), Gaps = 35/321 (10%)
Query: 138 QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRV- 196
Q++ + P G P ++ +P PR R +++ S Q PP +
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 197 PPTSPSDHQGPPHTL-VSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQ-----QDPAAP 250
PPTSP P L V+ T P+ + E + G T+ P P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 251 DVGSVPPVEVVYSQEPGAQPDLA---LARSLPPAEELPVET-PKRAGAEVSWEVSSPGPP 306
S+P V + ++P +A + LP + P + PK G ++ ++
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT----- 2543
Query: 307 PKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKS 366
+L + D P PT P + + S P + S + P P +
Sbjct: 2544 ---LNLVTSADYKLPSPTSPLSPHS--NKSSPRFSK-------SLTETYVVITLPSEPGT 2591
Query: 367 LIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQR 426
P+D + T P+G+ D P PP V+ P +S + +
Sbjct: 2592 ----PTDSSASQAITSWPLGSPSKDLVSVEPVF-SVVPPVTAVEIPISSEQTFYISGALQ 2646
Query: 427 ALGQPPPPEPTASSMASAPAS 447
P P SS +AP S
Sbjct: 2647 TFSATPVTAP--SSFQAAPTS 2665
>gi|150378539 piccolo isoform 1 [Homo sapiens]
Length = 5142
Score = 58.5 bits (140), Expect = 3e-08
Identities = 85/355 (23%), Positives = 127/355 (35%), Gaps = 53/355 (14%)
Query: 134 QELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTK 193
Q+++Q+E P + P L P P P Q G++ P + +G
Sbjct: 193 QKVVQKEQGKPEGIIKPPLQQQPPKPI---------PKQQGPGRD---PLQQDGTPKSIS 240
Query: 194 SRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQD------- 246
S+ P S PP T G + P + + LQ A P Q D
Sbjct: 241 SQQPEKIKSQ---PPGTGKPIQGPTQTPQTDHA---KLPLQRDASRPQTKQADIVRGESV 294
Query: 247 -PAAPDVGSVPPVEVVYSQEPGAQPDLALAR---SLPPAEELPVETPKRAGAEVSWEVSS 302
P+ P P + + P QP ++ + PPA+ + P A+ V
Sbjct: 295 KPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPAKPPAQPSGLTKPL---AQQPGTVKP 351
Query: 303 PGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSK-PERAAMNGADPISPQRVRGAVEAP 361
P PP P P P SE P P+ A +P + G + P
Sbjct: 352 PVQPPGTTKPPAQPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQPGPAKPP 411
Query: 362 ----GTPKSLI--PGPSDPGPAVNRTESPMGALQPDEA---EEWPGRP---QSHPPAPPV 409
GTPK L PG P A T++P+ P + + PG+ Q+ P PP
Sbjct: 412 TQQVGTPKPLAQQPGLQSPAKAPGPTKTPVQQPGPGKIPAQQAGPGKTSAQQTGPTKPPS 471
Query: 410 QAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGPLR 464
Q P ++ Q +PPP +P ++ P S P + PP + GP +
Sbjct: 472 QLPGPAKPP----PQQPGPAKPPPQQPGSAK----PPSQQPGSTKPPPQQPGPAK 518
Score = 57.0 bits (136), Expect = 8e-08
Identities = 98/388 (25%), Positives = 133/388 (34%), Gaps = 89/388 (22%)
Query: 62 PENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQG 121
P+ +AD R V+ P+ P KP P+ G AQ E+ AQ
Sbjct: 281 PQTKQADIVRGESVK--PSLPSPSKP---PIQQPTPGKPPAQQPGHEKSQPGPAKPPAQ- 334
Query: 122 PSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQW 181
PS G T PL QQ PV P T P P + P Q G E
Sbjct: 335 PS--GLTKPL-----AQQPGTVKPPVQPPGTTKPPAQP-----LGPAKPPAQQTGSE--- 379
Query: 182 PPRDEGLKAKTKSRVPPT--SPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQG 239
P E K ++ P +P+ GP GT K P+ + G LQ A+
Sbjct: 380 KPSSEQPGPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPK-PLAQQPG-----LQSPAKA 433
Query: 240 PHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETPKRAGAEVSWE 299
P T+ P G +P + PG + PP++
Sbjct: 434 PGPTKTPVQQPGPGKIPAQQA----GPGKTSAQQTGPTKPPSQ----------------- 472
Query: 300 VSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVE 359
+ P PP Q P P PP P +P A P S Q
Sbjct: 473 LPGPAKPPPQQ----------PGPAKPP----PQQP--------GSAKPPSQQ------- 503
Query: 360 APGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGL 419
PG+ K P P PGPA + P G+ +P + +P + P+P + S + +
Sbjct: 504 -PGSTK---PPPQQPGPAKPSPQQP-GSTKPPSQQPGSAKPSAQQPSPAKPSAQQSTKPV 558
Query: 420 IRVTTQRALGQPPPPEPTASSMASAPAS 447
+Q G+P P PT S A P S
Sbjct: 559 ----SQTGSGKPLQP-PTVSPSAKQPPS 581
Score = 53.5 bits (127), Expect = 9e-07
Identities = 68/293 (23%), Positives = 104/293 (35%), Gaps = 48/293 (16%)
Query: 202 SDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVV 261
SD + V++ + +G + LQ+ P QQ P + + +
Sbjct: 180 SDSEASQEETTKKQKVVQKEQGKPEGIIKPPLQQQPPKPIPKQQGPGRDPLQQDGTPKSI 239
Query: 262 YSQEPGAQPDLALARSLPPAEELPVE----TPKRAGAEVSWEVSSPGPPPKQAD------ 311
SQ+P +S PP P++ TP+ A++ + + P KQAD
Sbjct: 240 SSQQPEK------IKSQPPGTGKPIQGPTQTPQTDHAKLPLQRDASRPQTKQADIVRGES 293
Query: 312 ----LPDAKDSPGPQPT--DPPASEAPDRPSKPERAAMNGADPISPQRV-RGAVEAPGTP 364
LP P QPT PPA + S+P A P P + + + PGT
Sbjct: 294 VKPSLPSPSKPPIQQPTPGKPPAQQPGHEKSQPGPA----KPPAQPSGLTKPLAQQPGTV 349
Query: 365 KSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAP------------PVQAP 412
K + P P P+G +P + +P S P P P Q P
Sbjct: 350 KPPVQPPGTTKPPA----QPLGPAKPPAQQTGSEKPSSEQPGPKALAQPPGVGKTPAQQP 405
Query: 413 STSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSP---PANATAPPLRWGP 462
++ +V T + L Q P + A A P +P P P + GP
Sbjct: 406 GPAKPPTQQVGTPKPLAQQPGLQSPAK--APGPTKTPVQQPGPGKIPAQQAGP 456
Score = 48.5 bits (114), Expect = 3e-05
Identities = 87/391 (22%), Positives = 120/391 (30%), Gaps = 62/391 (15%)
Query: 86 KPVASPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPH 145
KP A PLGPA P A Q + PSS GP + L Q V
Sbjct: 360 KPPAQPLGPAK--PPAQQTGSEK-------------PSSEQ-PGP---KALAQPPGVGKT 400
Query: 146 PVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEG-LKAKTKSRVPPTSPSDH 204
P P P P Q +V T P Q G + P + G K + P P+
Sbjct: 401 PAQQPG----PAKPPTQ-QVGTPKPLAQQPGLQS--PAKAPGPTKTPVQQPGPGKIPAQQ 453
Query: 205 QGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQ 264
GP T +G K P +Q P + P P PP + ++
Sbjct: 454 AGPGKTSAQQTGPTKPP---------------SQLPGPAKPPPQQPGPAKPPPQQPGSAK 498
Query: 265 EPGAQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPT 324
P QP + PP + P + + PG A P Q T
Sbjct: 499 PPSQQPG---STKPPPQQPGPAKPSPQQPGSTKPPSQQPGSAKPSAQQPSPAKPSAQQST 555
Query: 325 DPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPG----PAVNR 380
P + +P +P + + P S + T + L+ P
Sbjct: 556 KPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPLCNTTELLLHVPEKANFNTCTECQT 615
Query: 381 TESPMGALQPD----EAEEW------PGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQ 430
T + P+ E +EW R AP +P + TT
Sbjct: 616 TVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLAPVPSSPQPKLKTAPVTTTSAVSKS 675
Query: 431 PPPPEPTASSMASAP---ASSPPANATAPPL 458
P P+ T+ +AP S P PPL
Sbjct: 676 SPQPQQTSPKKDAAPKQDLSKAPEPKKPPPL 706
Score = 46.6 bits (109), Expect = 1e-04
Identities = 92/411 (22%), Positives = 137/411 (33%), Gaps = 80/411 (19%)
Query: 111 PVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPP 170
PVT +++ T P Q + AP P P L PT A PP
Sbjct: 665 PVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPP 724
Query: 171 SLQHEGQEGQWPPRDEGLKAKT-KSRVPPTSPSDHQ--GPPHTLVSHSGTVKRPVLEGQG 227
+ PP++ + ++ K+ V P + P LVS S +P +
Sbjct: 725 EADSLSKPA--PPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSK 782
Query: 228 GFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQP----DLALARSLPPAEE 283
+ +E P T D A P P E V + A P D + P+ E
Sbjct: 783 -VQSQAEEKTTPPLKT--DSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSE 839
Query: 284 L-------PV---ETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPD 333
PV E PK+A ++S + + P PK + P PGP+PT P
Sbjct: 840 SKGQKQVDPVQKKEEPKKAQTKMSPKPDAK-PMPKGSPTP-----PGPRPTAGQTVPTPQ 893
Query: 334 RPSKPE----RAAMN--------GADPISPQR-VRGAV---------------------- 358
+ KP+ R ++N + P +PQ V G +
Sbjct: 894 QSPKPQEQSRRFSLNLGSITDAPKSQPTTPQETVTGKLFGFGASIFSQASNLISTAGQPG 953
Query: 359 ----EAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPST 414
PG P P PS P P G P A+ P + ++ PA P
Sbjct: 954 PHSQSGPGAPMKQAPAPSQP-PTSQGPPKSTGQAPPAPAKSIPVKKETKAPAAEKLEPKA 1012
Query: 415 SRRGLIRVTTQRALGQPPPPEPTASSMASAP---------ASSPPANATAP 456
+ ++ T + PPP + S+ + P SP +T P
Sbjct: 1013 EQAPTVKRTETE---KKPPPIKDSKSLTAEPQKAVLPTKLEKSPKPESTCP 1060
Score = 44.3 bits (103), Expect = 6e-04
Identities = 112/522 (21%), Positives = 161/522 (30%), Gaps = 123/522 (23%)
Query: 24 PALGRGFPRPLENSEIPMIPGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEM 83
PA G +PL + P P G+ ++P A + P P A + P+ E
Sbjct: 332 PAQPSGLTKPLAQQPGTVKPPVQPPGT--TKPPAQPLGPAKPPAQQTGSEK----PSSEQ 385
Query: 84 PEKPVASPLGPALYGPKA-AQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAV 142
P GPKA AQ + P G PL Q LQ A
Sbjct: 386 P-------------GPKALAQPPGVGKTPAQQPGPAKPPTQQVGTPKPLAQQPGLQSPAK 432
Query: 143 APHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPS 202
AP P TP +Q +P G K + P PS
Sbjct: 433 APGPT---------KTPVQQPGPGKIPAQQAGPG------------KTSAQQTGPTKPPS 471
Query: 203 DHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDV----GSVPPV 258
GP G K P + Q + P Q PA P + PP
Sbjct: 472 QLPGPAKPPPQQPGPAKPPPQQPGSAKPPSQQPGSTKPPPQQPGPAKPSPQQPGSTKPPS 531
Query: 259 EVVYSQEPGAQ---------------------------PDLALARSLPPAEELP------ 285
+ S +P AQ P ++ + PP++ LP
Sbjct: 532 QQPGSAKPSAQQPSPAKPSAQQSTKPVSQTGSGKPLQPPTVSPSAKQPPSQGLPKTICPL 591
Query: 286 -------VETPKRAGAEVSWEVSSP-------GPPPKQADLPD-------AKDSPGPQPT 324
+ P++A E + P P ++ + K + G
Sbjct: 592 CNTTELLLHVPEKANFNTCTECQTTVCSLCGFNPNPHLTEVKEWLCLNCQMKRALGGDLA 651
Query: 325 DPPASEAPDRPSKP--ERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTE 382
P+S P + P +A++ + P Q AP S P P P P V +
Sbjct: 652 PVPSSPQPKLKTAPVTTTSAVSKSSPQPQQTSPKKDAAPKQDLSKAPEPKKPPPLVKQPT 711
Query: 383 ---SPMG-ALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTA 438
SP A QP EA+ PAPP + S + V + QP +PT
Sbjct: 712 LHGSPSAKAKQPPEAD------SLSKPAPPKEPSVPSEQDKAPVADDKP-KQPKMVKPTT 764
Query: 439 SSMASAPASSPP-----------ANATAPPLRWGPLRRVLSF 469
++S+ A++ P T PPL+ + SF
Sbjct: 765 DLVSSSSATTKPDIPSSKVQSQAEEKTTPPLKTDSAKPSQSF 806
Score = 37.4 bits (85), Expect = 0.069
Identities = 46/229 (20%), Positives = 78/229 (34%), Gaps = 42/229 (18%)
Query: 273 ALARSLPPAEELPVETPKRAGAEVSWEVSSPGP--PPKQADLPDAKDSPGPQPTDPPASE 330
A+++S P ++ +PK+ A +P P PP P SP + PP ++
Sbjct: 671 AVSKSSPQPQQT---SPKKDAAPKQDLSKAPEPKKPPPLVKQPTLHGSPSAKAKQPPEAD 727
Query: 331 A---------PDRPSKPERAAMNGADPISPQRVRGAVE----APGTPKSLIPGPSDPGPA 377
+ P PS+ ++A + P P+ V+ + + T K IP A
Sbjct: 728 SLSKPAPPKEPSVPSEQDKAPVADDKPKQPKMVKPTTDLVSSSSATTKPDIPSSKVQSQA 787
Query: 378 VNRTESPMGALQPDEAEEWP--------------GRPQSHPPAPPVQAPSTSRRGLIRV- 422
+T P+ ++ +P RP S PS+ +G +V
Sbjct: 788 EEKTTPPLKTDSAKPSQSFPPTGEKVSPFDSKAIPRPASDSKIISHPGPSSESKGQKQVD 847
Query: 423 ---------TTQRALGQPPPPEPTASSMASAPASSPPANATAPPLRWGP 462
Q + P +P + P P A T P + P
Sbjct: 848 PVQKKEEPKKAQTKMSPKPDAKPMPKGSPTPPGPRPTAGQTVPTPQQSP 896
Score = 36.6 bits (83), Expect = 0.12
Identities = 38/158 (24%), Positives = 57/158 (36%), Gaps = 12/158 (7%)
Query: 269 QPDLALARSLPPAEELPVETPKRAGAEVSWEVSS--PGPPPKQADLPDAKDSPGPQPTDP 326
+P L P LP + P+ S ++S+ P PPP P P P P P
Sbjct: 2371 KPASQLPSGSPSVSSLPAK-PRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLPP 2429
Query: 327 PASEAPD-RPSK------PERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVN 379
P S P P K P A D ++ + + G P + I + P
Sbjct: 2430 PTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPPK 2489
Query: 380 RTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRR 417
+ P G + E P +P P Q P+T+++
Sbjct: 2490 PSSIPSGLVFTHRPE--PSKPPIAPKPVIPQLPTTTQK 2525
Score = 33.1 bits (74), Expect = 1.3
Identities = 37/159 (23%), Positives = 55/159 (34%), Gaps = 20/159 (12%)
Query: 211 LVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQP 270
++ H ++ G G + Q P + D P+E+ YS A
Sbjct: 3549 IIKHISAPEKTYKGGSLGCQTEADSDTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRADS 3608
Query: 271 DLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASE 330
+ LA S P ++PK + +S SPG + A +P K P P P
Sbjct: 3609 TVQLAPS-------PPKSPKVLYSPIS--PLSPGKALESAFVPYEK--PLPDDISPQKVL 3657
Query: 331 APDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIP 369
PD P P SP+ + + PK L P
Sbjct: 3658 HPDMAKVP---------PASPKTAKMMQRSMSDPKPLSP 3687
Score = 32.3 bits (72), Expect = 2.2
Identities = 35/134 (26%), Positives = 50/134 (37%), Gaps = 16/134 (11%)
Query: 317 DSPGPQ---PTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIP--GP 371
D+ PQ T PP + P + ++ AD V+ A P +PK L P
Sbjct: 3574 DTQSPQYLSATSPPKDKKRPTPLEIGYSSHLRAD----STVQLAPSPPKSPKVLYSPISP 3629
Query: 372 SDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQP 431
PG A+ P PD+ PP +P T++ QR++ P
Sbjct: 3630 LSPGKALESAFVPYEKPLPDDISPQKVLHPDMAKVPPA-SPKTAKM------MQRSMSDP 3682
Query: 432 PPPEPTASSMASAP 445
P PTA + AP
Sbjct: 3683 KPLSPTADESSRAP 3696
Score = 30.8 bits (68), Expect = 6.5
Identities = 68/321 (21%), Positives = 111/321 (34%), Gaps = 35/321 (10%)
Query: 138 QQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRV- 196
Q++ + P G P ++ +P PR R +++ S Q PP +
Sbjct: 2369 QEKPASQLPSGSPSVSSLPAKPRPFFRSSSLDISAQPPPPPPPPPPPPPPPPPPPPPPLP 2428
Query: 197 PPTSPSDHQGPPHTL-VSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQ-----QDPAAP 250
PPTSP P L V+ T P+ + E + G T+ P P
Sbjct: 2429 PPTSPKPTILPKKKLTVASPVTTATPLFDAVTTLETTAVLRSNGLPVTRICTTAPPPVPP 2488
Query: 251 DVGSVPPVEVVYSQEPGAQPDLA---LARSLPPAEELPVET-PKRAGAEVSWEVSSPGPP 306
S+P V + ++P +A + LP + P + PK G ++ ++
Sbjct: 2489 KPSSIPSGLVFTHRPEPSKPPIAPKPVIPQLPTTTQKPTDIHPKPTGLSLTSSMT----- 2543
Query: 307 PKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKS 366
+L + D P PT P + + S P + S + P P +
Sbjct: 2544 ---LNLVTSADYKLPSPTSPLSPHS--NKSSPRFSK-------SLTETYVVITLPSEPGT 2591
Query: 367 LIPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQR 426
P+D + T P+G+ D P PP V+ P +S + +
Sbjct: 2592 ----PTDSSASQAITSWPLGSPSKDLVSVEPVF-SVVPPVTAVEIPISSEQTFYISGALQ 2646
Query: 427 ALGQPPPPEPTASSMASAPAS 447
P P SS +AP S
Sbjct: 2647 TFSATPVTAP--SSFQAAPTS 2665
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 58.5 bits (140), Expect = 3e-08
Identities = 96/375 (25%), Positives = 135/375 (36%), Gaps = 54/375 (14%)
Query: 110 LPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVP 169
LP ++ G S G L +EL + + + +GH + +LR +
Sbjct: 490 LPQYHKQLVSSGYDSMGLVADLTWEEL---QEIGVNKLGHQKKLMLGVKRLAELRRGLLQ 546
Query: 170 -PSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQ-- 226
+L G+ P ++ P T+ GP L++ G+ P L+
Sbjct: 547 GEALSEGGRRLAKGPELMAIEGLENGEGPATA-----GP--RLLTFQGSELSPELQAAMA 599
Query: 227 -GGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELP 285
GG E A+ P +Q+ A GS E Q G P R+LP E P
Sbjct: 600 GGGPEPLPLPPARSP--SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP 657
Query: 286 VETPKRAGAEVSWEVSSPGPPPKQADLPDAKDS---PGPQPTDPPA-SEAPDRPSKPERA 341
PK + + GPPP P S PGP P P A S P+ P
Sbjct: 658 ---PKLCSS-----LPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPP-- 707
Query: 342 AMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAE--EWPGR 399
DP P+R ++ PG + G A E P+G+ A PGR
Sbjct: 708 -----DPPRPKRRSHSLSRPGPTE---------GDAEGEAEGPVGSTLGSYATLTRRPGR 753
Query: 400 P---QSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAP 456
++ P P A T R + +R PPPP P S S P+ PP +P
Sbjct: 754 SALVRTSPSVTPTPARGTPRSQSFALRARRK--GPPPPPPKRLSSVSGPSPEPPPLDESP 811
Query: 457 PLR---WGPLRRVLS 468
+ GP RR LS
Sbjct: 812 GPKEGATGPRRRTLS 826
Score = 56.6 bits (135), Expect = 1e-07
Identities = 114/480 (23%), Positives = 155/480 (32%), Gaps = 95/480 (19%)
Query: 90 SPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGH 149
S L P L A G + LP A+ PS G QE AP P G
Sbjct: 588 SELSPELQAAMAGGGPEPLPLPP------ARSPSQES-IGARSRGSGHSQEQPAPQPSGG 640
Query: 150 PHLTFIPTTPR-RQLRVATVPPSLQHEGQEGQWPPR-----DEGLKAKTKSRVPPTSP-- 201
P+ P+ R L T P GQ PP +G + PP +P
Sbjct: 641 D-----PSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWA 695
Query: 202 -SDHQGPPHTLVSHSGTVKRP-VLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVE 259
S GPP T +R L G E + A+GP VGS
Sbjct: 696 FSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGP-----------VGSTLGSY 744
Query: 260 VVYSQEPGAQPDLALARSLPPAEELPVE-TPKRAGAEVSWEVSSPGPPPKQA-------- 310
++ PG AL R+ P P TP+ + P PPP +
Sbjct: 745 ATLTRRPGRS---ALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 801
Query: 311 -DLPDAKDSPGPQ----------------PTDPPASEAPDRPSKPERAAMNGADPISPQR 353
+ P +SPGP+ P++PP AP P+ G + P R
Sbjct: 802 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 861
Query: 354 ----------VRGAVEAPGTPKSLIPGPSD----PGPAVNRTESPMGALQPD-------- 391
G + PK P P + PG N TES +P
Sbjct: 862 GSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQ 921
Query: 392 -------EAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASA 444
A PG P P ++P S ++ A G P P P+ +
Sbjct: 922 TALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPV 981
Query: 445 PASSPPANATAPPLRW-GPLRRVLSFSWELHVYGVGVLFLLPALLALAALAAAPAGPRLA 503
P P ++ RW G + + L V G G P +++A A +GP+LA
Sbjct: 982 PPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGT---APKPVSVACTQLAFSGPKLA 1038
Score = 46.2 bits (108), Expect = 1e-04
Identities = 110/435 (25%), Positives = 144/435 (33%), Gaps = 108/435 (24%)
Query: 43 PGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAA 102
PGA S + P A P P+ SH S R P E E P+G L
Sbjct: 690 PGAPWAFSYLAGPPATPPDPPRPKRRSHSLS--RPGPTEGDAEGEAEGPVGSTL-----G 742
Query: 103 QGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPV-GHPHLTFIPTTPRR 161
A R P G S+ T P +V P P G P RR
Sbjct: 743 SYATLTRRP---------GRSALVRTSP----------SVTPTPARGTPRSQSFALRARR 783
Query: 162 QLRVATVPPSLQH-EGQEGQWPPRDEGLKAKTKSRVP-------PTSPSDHQGPPHTLVS 213
+ P L G + PP DE K + P P PS+ GPP
Sbjct: 784 KGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGP 843
Query: 214 HSGTVKR-PVLEG----QGGFEEHLQEAAQGPHFTQQ--DPAAPDVGSVPPVEVVYSQEP 266
S T + P EG +G E L A +G +Q PA P PP E P
Sbjct: 844 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP-----PPRETPVP--P 896
Query: 267 GAQPDLA----LARSLPPAEELPVETPKRAG--AEVSWEVSSPGPPPKQADLPDAKDSPG 320
G +L + R E P++T A A + ++P P P + P A P
Sbjct: 897 GLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQ 956
Query: 321 PQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNR 380
P+P+ PA P P++P +P P P PGP
Sbjct: 957 PEPSSLPAQGVP--------------TPLAP-----------SPAMQPPVPPCPGP---- 987
Query: 381 TESPMGALQPDEAEEWPGRPQSHPPAPP-----VQAPSTSRRGLIRVTTQRALGQP---- 431
L+ A W G ++ PPA P V T+ + + TQ A P
Sbjct: 988 ------GLESSAASRWNG--ETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAP 1039
Query: 432 -------PPPEPTAS 439
PPP P ++
Sbjct: 1040 RLGPRPVPPPRPEST 1054
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 58.5 bits (140), Expect = 3e-08
Identities = 96/375 (25%), Positives = 135/375 (36%), Gaps = 54/375 (14%)
Query: 110 LPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVP 169
LP ++ G S G L +EL + + + +GH + +LR +
Sbjct: 572 LPQYHKQLVSSGYDSMGLVADLTWEEL---QEIGVNKLGHQKKLMLGVKRLAELRRGLLQ 628
Query: 170 -PSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQ-- 226
+L G+ P ++ P T+ GP L++ G+ P L+
Sbjct: 629 GEALSEGGRRLAKGPELMAIEGLENGEGPATA-----GP--RLLTFQGSELSPELQAAMA 681
Query: 227 -GGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELP 285
GG E A+ P +Q+ A GS E Q G P R+LP E P
Sbjct: 682 GGGPEPLPLPPARSP--SQESIGARSRGSGHSQEQPAPQPSGGDPSPPQERNLPEGTERP 739
Query: 286 VETPKRAGAEVSWEVSSPGPPPKQADLPDAKDS---PGPQPTDPPA-SEAPDRPSKPERA 341
PK + + GPPP P S PGP P P A S P+ P
Sbjct: 740 ---PKLCSS-----LPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWAFSYLAGPPATPP-- 789
Query: 342 AMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGALQPDEAE--EWPGR 399
DP P+R ++ PG + G A E P+G+ A PGR
Sbjct: 790 -----DPPRPKRRSHSLSRPGPTE---------GDAEGEAEGPVGSTLGSYATLTRRPGR 835
Query: 400 P---QSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAP 456
++ P P A T R + +R PPPP P S S P+ PP +P
Sbjct: 836 SALVRTSPSVTPTPARGTPRSQSFALRARRK--GPPPPPPKRLSSVSGPSPEPPPLDESP 893
Query: 457 PLR---WGPLRRVLS 468
+ GP RR LS
Sbjct: 894 GPKEGATGPRRRTLS 908
Score = 56.6 bits (135), Expect = 1e-07
Identities = 114/480 (23%), Positives = 155/480 (32%), Gaps = 95/480 (19%)
Query: 90 SPLGPALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPVGH 149
S L P L A G + LP A+ PS G QE AP P G
Sbjct: 670 SELSPELQAAMAGGGPEPLPLPP------ARSPSQES-IGARSRGSGHSQEQPAPQPSGG 722
Query: 150 PHLTFIPTTPR-RQLRVATVPPSLQHEGQEGQWPPR-----DEGLKAKTKSRVPPTSP-- 201
P+ P+ R L T P GQ PP +G + PP +P
Sbjct: 723 D-----PSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPWA 777
Query: 202 -SDHQGPPHTLVSHSGTVKRP-VLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVE 259
S GPP T +R L G E + A+GP VGS
Sbjct: 778 FSYLAGPPATPPDPPRPKRRSHSLSRPGPTEGDAEGEAEGP-----------VGSTLGSY 826
Query: 260 VVYSQEPGAQPDLALARSLPPAEELPVE-TPKRAGAEVSWEVSSPGPPPKQA-------- 310
++ PG AL R+ P P TP+ + P PPP +
Sbjct: 827 ATLTRRPGRS---ALVRTSPSVTPTPARGTPRSQSFALRARRKGPPPPPPKRLSSVSGPS 883
Query: 311 -DLPDAKDSPGPQ----------------PTDPPASEAPDRPSKPERAAMNGADPISPQR 353
+ P +SPGP+ P++PP AP P+ G + P R
Sbjct: 884 PEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPPSR 943
Query: 354 ----------VRGAVEAPGTPKSLIPGPSD----PGPAVNRTESPMGALQPD-------- 391
G + PK P P + PG N TES +P
Sbjct: 944 GSSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCREREPLQ 1003
Query: 392 -------EAEEWPGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASA 444
A PG P P ++P S ++ A G P P P+ +
Sbjct: 1004 TALLAFGVASATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPV 1063
Query: 445 PASSPPANATAPPLRW-GPLRRVLSFSWELHVYGVGVLFLLPALLALAALAAAPAGPRLA 503
P P ++ RW G + + L V G G P +++A A +GP+LA
Sbjct: 1064 PPCPGPGLESSAASRWNGETEPPAAPAALLKVPGAGT---APKPVSVACTQLAFSGPKLA 1120
Score = 46.2 bits (108), Expect = 1e-04
Identities = 110/435 (25%), Positives = 144/435 (33%), Gaps = 108/435 (24%)
Query: 43 PGAHPKGSVGSEPQAFDVFPENPRADSHRNSDVRHAPAEEMPEKPVASPLGPALYGPKAA 102
PGA S + P A P P+ SH S R P E E P+G L
Sbjct: 772 PGAPWAFSYLAGPPATPPDPPRPKRRSHSLS--RPGPTEGDAEGEAEGPVGSTL-----G 824
Query: 103 QGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPHPV-GHPHLTFIPTTPRR 161
A R P G S+ T P +V P P G P RR
Sbjct: 825 SYATLTRRP---------GRSALVRTSP----------SVTPTPARGTPRSQSFALRARR 865
Query: 162 QLRVATVPPSLQH-EGQEGQWPPRDEGLKAKTKSRVP-------PTSPSDHQGPPHTLVS 213
+ P L G + PP DE K + P P PS+ GPP
Sbjct: 866 KGPPPPPPKRLSSVSGPSPEPPPLDESPGPKEGATGPRRRTLSEPAGPSEPPGPPAPAGP 925
Query: 214 HSGTVKR-PVLEG----QGGFEEHLQEAAQGPHFTQQ--DPAAPDVGSVPPVEVVYSQEP 266
S T + P EG +G E L A +G +Q PA P PP E P
Sbjct: 926 ASDTEEEEPGPEGTPPSRGSSGEGLPFAEEGNLTIKQRPKPAGP-----PPRETPVP--P 978
Query: 267 GAQPDLA----LARSLPPAEELPVETPKRAG--AEVSWEVSSPGPPPKQADLPDAKDSPG 320
G +L + R E P++T A A + ++P P P + P A P
Sbjct: 979 GLDFNLTESDTVKRRPKCREREPLQTALLAFGVASATPGPAAPLPSPTPGESPPASSLPQ 1038
Query: 321 PQPTDPPASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNR 380
P+P+ PA P P++P +P P P PGP
Sbjct: 1039 PEPSSLPAQGVP--------------TPLAP-----------SPAMQPPVPPCPGP---- 1069
Query: 381 TESPMGALQPDEAEEWPGRPQSHPPAPP-----VQAPSTSRRGLIRVTTQRALGQP---- 431
L+ A W G ++ PPA P V T+ + + TQ A P
Sbjct: 1070 ------GLESSAASRWNG--ETEPPAAPAALLKVPGAGTAPKPVSVACTQLAFSGPKLAP 1121
Query: 432 -------PPPEPTAS 439
PPP P ++
Sbjct: 1122 RLGPRPVPPPRPEST 1136
>gi|112382226 atrophin-1 like protein isoform b [Homo sapiens]
Length = 1012
Score = 58.5 bits (140), Expect = 3e-08
Identities = 98/377 (25%), Positives = 122/377 (32%), Gaps = 60/377 (15%)
Query: 94 PALYGPKAAQGAQRERLPVTDDLQMAQGPSSHGWTGPLDSQELLQQEAVAPH----PVGH 149
PAL P A P T L GP+ P Q P PV H
Sbjct: 185 PALQAPTGVTPAPSSAPPGTPQLP-TPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPH 243
Query: 150 PHLTFIPTT-PRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPP 208
H+ P P+R PPS PP L+ T S P++PS Q P
Sbjct: 244 THIQQAPALHPQR-------PPSPHPPPHPSPHPP----LQPLTGSAGQPSAPSHAQPPL 292
Query: 209 HTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEP-G 267
H GQG H +A GP Q P P +PP + Q P G
Sbjct: 293 H---------------GQGPPGPHSLQA--GPLL--QHPGPPQPFGLPP-QASQGQAPLG 332
Query: 268 AQPDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPP 327
P A + + +LP + E P P + +P PQ P
Sbjct: 333 TSPAAAYPHT---SLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQ 389
Query: 328 ASEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGPSDPGPAVNRTESPMGA 387
A + P S P +MN P P + + P S P P P P+
Sbjct: 390 AHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQ----SQPL-- 443
Query: 388 LQPDEAEEWPGRPQSHP-PAPPVQAPSTSRRGLIRVTTQRALGQ-------PPPPEPTAS 439
P + PG QS P PP P T GL +V Q Q PPP P
Sbjct: 444 --PSSPAQPPGLTQSQNLPPPPASHPPT---GLHQVAPQPPFAQHPFVPGGPPPITPPTC 498
Query: 440 SMASAPASSPPANATAP 456
S P + P +A P
Sbjct: 499 PSTSTPPAGPGTSAQPP 515
Score = 51.6 bits (122), Expect = 4e-06
Identities = 75/327 (22%), Positives = 112/327 (34%), Gaps = 56/327 (17%)
Query: 178 EGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAA 237
EG P+D ++ S P+ + + + P L+ G A
Sbjct: 142 EGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAP 201
Query: 238 QGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVETP--KRAGAE 295
G P P G P V P P + A + P A PV ++A A
Sbjct: 202 PGT------PQLPTPGPTPSATAV---PPQGSPTASQAPNQPQAPTAPVPHTHIQQAPAL 252
Query: 296 VSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKPERAA--MNGADPISPQR 353
SP PPP P P P P + + +PS P A ++G P P
Sbjct: 253 HPQRPPSPHPPPH----------PSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHS 302
Query: 354 VRGA--VEAPGTPKSL----------IPGPSDPGPAVNRTESPMGALQPDEAEEWPGRPQ 401
++ ++ PG P+ P + P A T + A Q + P R Q
Sbjct: 303 LQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQ 362
Query: 402 SHPPAP----PVQAPSTSRRGLIRVTTQRALGQPP--------------PPEPTASSMAS 443
PPAP ++ P T+ + ++ +A PP PP P ++S
Sbjct: 363 PLPPAPLAMPHIKPPPTTP--IPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSS 420
Query: 444 APASSPPANATAPPLRWGPLRRVLSFS 470
PP+ A PPL+ P + L S
Sbjct: 421 LSTHHPPS-AHPPPLQLMPQSQPLPSS 446
Score = 49.3 bits (116), Expect = 2e-05
Identities = 87/392 (22%), Positives = 128/392 (32%), Gaps = 53/392 (13%)
Query: 43 PGAHPKGSVGSEPQAFDVFPENP----RADSHRNSDVRHAPAEEMPEKPVASPLGPALYG 98
PG + G P A V P+ +A + + P + + P P P
Sbjct: 202 PGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPH 261
Query: 99 PKAAQGAQRERLPVTDDLQMAQGPSS-----HGWTGP----LDSQELLQQEAVAPHPVGH 149
P P+T PS HG P L + LLQ P P G
Sbjct: 262 PPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPG-PPQPFGL 320
Query: 150 PHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLKAKTKSRVPPTSPSDHQGPPH 209
P P + Q + T P+ + Q P L+++ R P P+ PH
Sbjct: 321 P-----PQASQGQAPLGT-SPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAP-LAMPH 373
Query: 210 TLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFTQQDPAAPDVGSVPPVEVVYSQEPGAQ 269
+ T P L Q PH + P + + PP P +
Sbjct: 374 --IKPPPTTPIPQLPAP-------QAHKHPPHLSGPSPFSMNANLPPP--------PALK 416
Query: 270 PDLALARSLPPAEELPVETPKRAGAEVSWEVSSPGPPPKQADLPDAKDSPGPQPTDPPA- 328
P +L+ PP+ P P + + SSP PP L +++ P P + PP
Sbjct: 417 PLSSLSTHHPPSAHPP---PLQLMPQSQPLPSSPAQPP---GLTQSQNLPPPPASHPPTG 470
Query: 329 --SEAPDRPSKPERAAMNGADPISPQRVRGAVEAPGTPKSLIPGP-----SDPGPAVNRT 381
AP P G PI+P P P + P + G +
Sbjct: 471 LHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGS 530
Query: 382 ESPMGALQ-PDEAEEWPGRPQSHPPAPPVQAP 412
P+ +Q +EA + P+S PP P +P
Sbjct: 531 SCPLPTVQIKEEALDDAEEPESPPPPPRSPSP 562
Score = 49.3 bits (116), Expect = 2e-05
Identities = 91/366 (24%), Positives = 128/366 (34%), Gaps = 84/366 (22%)
Query: 33 PLENSEIPMIPGAHPKGSVGSEP----------QAFDVFPENPRADSHRNSDVRHAPAEE 82
P+ ++ I P HP+ P Q P A SH + H
Sbjct: 240 PVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPL-HGQGPP 298
Query: 83 MPEKPVASPL-----GPALYG--PKAAQG------AQRERLPVTDDLQMAQGPSSHGWTG 129
P A PL P +G P+A+QG + P T LQ+ S+
Sbjct: 299 GPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTS-LQLPASQSA----- 352
Query: 130 PLDSQELLQQEAVAPHPVGHPHLTFIPTTPRRQLRVATVPPSLQHEGQEGQWPPRDEGLK 189
L SQ+ +++ + P P+ PH+ PTTP QL P + +H PP G
Sbjct: 353 -LQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQL---PAPQAHKH-------PPHLSG-- 399
Query: 190 AKTKSRVPPTSPSDHQGPPHTL-------VSHSGTVKRPVLEGQGGFEEHLQEAAQGPHF 242
P S + + PP L H + P L+ + AQ P
Sbjct: 400 ------PSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGL 453
Query: 243 TQQDPAAPDVGSVPP--VEVVYSQEPGAQ------------PDLALARSLPPA-----EE 283
TQ P S PP + V Q P AQ P + S PPA +
Sbjct: 454 TQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQ 513
Query: 284 LPVETPKRAGAEVSWEVSSPGPPP--KQADLPDAKDSPGPQPTDPPASEAP-----DRPS 336
P +G ++ S P P K+ L DA++ P P PP S +P D PS
Sbjct: 514 PPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPP--PPRSPSPEPTVVDTPS 571
Query: 337 KPERAA 342
++A
Sbjct: 572 HASQSA 577
Score = 48.5 bits (114), Expect = 3e-05
Identities = 71/301 (23%), Positives = 105/301 (34%), Gaps = 70/301 (23%)
Query: 184 RDEGLKAKTKSRVPPTSPSDHQGPPHTLVSHSGTVKRPVLEGQGGFEEHLQEAAQGPHFT 243
R K KT+ P SPS+ +G S S +V E + P
Sbjct: 109 RTSSKKTKTQEISRPNSPSEGEGES----SDSRSVN--------------DEGSSDPKDI 150
Query: 244 QQDPAAPDVGSVPPVEVVYSQEPGAQPDLALARSLPPAEELPVE-TPKRAGAEVSW-EVS 301
QD + P + + AQ + A+ PPA + P TP + A ++
Sbjct: 151 DQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQ--PPALQAPTGVTPAPSSAPPGTPQLP 208
Query: 302 SPGPPPKQADLPDAKDSPGPQPTDPPASEAPDRPSKP----------ERAAMNGADPISP 351
+PGP P +P PQ + P AS+AP++P P + A++ P SP
Sbjct: 209 TPGPTPSATAVP-------PQGS-PTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSP 260
Query: 352 ------------QRVRGAVEAPGTPKSLIP---GPSDPGPAVNRTESPMGALQPDEAEEW 396
Q + G+ P P P G PGP +LQ +
Sbjct: 261 HPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGP---------HSLQAGPLLQH 311
Query: 397 PGRPQSHPPAPPVQAPSTSRRGLIRVTTQRALGQPPPPEPTASSMASAPASSPPANATAP 456
PG PQ P P + +G + T A P +S ++ + PP P
Sbjct: 312 PGPPQ------PFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLP 365
Query: 457 P 457
P
Sbjct: 366 P 366
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.134 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,530,837
Number of Sequences: 37866
Number of extensions: 3403421
Number of successful extensions: 26787
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 183
Number of HSP's successfully gapped in prelim test: 1694
Number of HSP's that attempted gapping in prelim test: 15475
Number of HSP's gapped (non-prelim): 8840
length of query: 981
length of database: 18,247,518
effective HSP length: 112
effective length of query: 869
effective length of database: 14,006,526
effective search space: 12171671094
effective search space used: 12171671094
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.