Search of human proteins with 67782365

Search of human proteins with 67782365

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67782365 keratin 7 [Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67782365 keratin 7 [Homo sapiens]                                  890   0.0  
gi|119395754 keratin 5 [Homo sapiens]                                 526   e-149
gi|153791158 keratin 75 [Homo sapiens]                                523   e-148
gi|5031839 keratin 6A [Homo sapiens]                                  519   e-147
gi|155969697 keratin 6C [Homo sapiens]                                515   e-146
gi|119703753 keratin 6B [Homo sapiens]                                514   e-146
gi|4504919 keratin 8 [Homo sapiens]                                   509   e-144
gi|109148552 keratin 3 [Homo sapiens]                                 488   e-138
gi|109255249 keratin 4 [Homo sapiens]                                 486   e-137
gi|32567786 keratin 6L [Homo sapiens]                                 479   e-135
gi|153791670 keratin 76 [Homo sapiens]                                478   e-135
gi|28173564 keratin 73 [Homo sapiens]                                 473   e-133
gi|15431316 keratin, hair, basic, 4 [Homo sapiens]                    468   e-132
gi|28372503 keratin 72 isoform 1 [Homo sapiens]                       466   e-131
gi|226246663 keratin 72 isoform 1 [Homo sapiens]                      466   e-131
gi|15618995 keratin 71 [Homo sapiens]                                 459   e-129
gi|119395750 keratin 1 [Homo sapiens]                                 452   e-127
gi|148612803 keratin 6 irs4 [Homo sapiens]                            441   e-124
gi|194018511 keratin 77 [Homo sapiens]                                436   e-122
gi|47132620 keratin 2 [Homo sapiens]                                  430   e-120
gi|4504935 keratin 85 [Homo sapiens]                                  429   e-120
gi|27477127 keratin 82 [Homo sapiens]                                 428   e-120
gi|89357932 keratin 5b [Homo sapiens]                                 420   e-117
gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo sap...   407   e-113
gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo sap...   407   e-113
gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo sap...   407   e-113
gi|14318422 keratin 86 [Homo sapiens]                                 407   e-113
gi|169790853 keratin, hair, basic, 1 [Homo sapiens]                   407   e-113
gi|169790841 keratin 83 [Homo sapiens]                                402   e-112
gi|226246665 keratin 72 isoform 2 [Homo sapiens]                      372   e-103

>gi|67782365 keratin 7 [Homo sapiens]
          Length = 469

 Score =  890 bits (2299), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG 60
           MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG
Sbjct: 1   MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG 60

Query: 61  AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLE 120
           AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLE
Sbjct: 61  AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLE 120

Query: 121 TKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKY 180
           TKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKY
Sbjct: 121 TKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKY 180

Query: 181 EDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQI 240
           EDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQI
Sbjct: 181 EDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQI 240

Query: 241 SDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDD 300
           SDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDD
Sbjct: 241 SDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDD 300

Query: 301 LRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAA 360
           LRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAA
Sbjct: 301 LRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAA 360

Query: 361 LQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTG 420
           LQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTG
Sbjct: 361 LQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTG 420

Query: 421 GSSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASRRSARD 469
           GSSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASRRSARD
Sbjct: 421 GSSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASRRSARD 469


>gi|119395754 keratin 5 [Homo sapiens]
          Length = 590

 Score =  526 bits (1356), Expect = e-149
 Identities = 297/487 (60%), Positives = 353/487 (72%), Gaps = 20/487 (4%)

Query: 1   MSIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGP-- 58
           +SI  S   F +R  A +G G      +    G G  +  G G           +GGP  
Sbjct: 74  ISISTSGGSFRNRFGAGAGGGYGFGGGAGSGFGFGGGAGGGFGLGGG-AGFGGGFGGPGF 132

Query: 59  ---VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQ 115
                 GI+EVT+NQSLL PL L  DPS+QRVR EE EQIKTLNNKFASFIDKVRFLEQQ
Sbjct: 133 PVCPPGGIQEVTVNQSLLTPLNLQIDPSIQRVRTEEREQIKTLNNKFASFIDKVRFLEQQ 192

Query: 116 NKLLETKWTLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVE 174
           NK+L+TKWTLLQEQ +      L  +FE  I  LR QL+++  + GRL++ELR+MQD+VE
Sbjct: 193 NKVLDTKWTLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVE 252

Query: 175 DFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELT 234
           DFKNKYEDEIN RT AENEFV+LKKDVDAAYM+KVELEAKVDAL DEINF++   + EL+
Sbjct: 253 DFKNKYEDEINKRTTAENEFVMLKKDVDAAYMNKVELEAKVDALMDEINFMKMFFDAELS 312

Query: 235 ELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQA 294
           ++Q+ +SDTSVVLSMDN+R+LDLD IIAEVKAQYEE+A  SR EAE+WYQTK+E LQ  A
Sbjct: 313 QMQTHVSDTSVVLSMDNNRNLDLDSIIAEVKAQYEEIANRSRTEAESWYQTKYEELQQTA 372

Query: 295 GKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQ 354
           G+HGDDLRNT++EISEMNR IQRL+AEIDN+K Q A L+ AIA+AE+RGELALKDAR K 
Sbjct: 373 GRHGDDLRNTKHEISEMNRMIQRLRAEIDNVKKQCANLQNAIADAEQRGELALKDARNKL 432

Query: 355 EELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNIS 414
            ELE ALQ+ KQDMAR LREYQELM+ KLALD+EIATYRKLLEGEE RL+G+GVG VNIS
Sbjct: 433 AELEEALQKAKQDMARLLREYQELMNTKLALDVEIATYRKLLEGEECRLSGEGVGPVNIS 492

Query: 415 VMNST------GGSSSGGGIGLTLGGTMG-------SNALSFSSSAGPGLLKAYSIRTAS 461
           V+ S+       GS  GGG+G  LGG +G       S +   SSS G GL    S+  + 
Sbjct: 493 VVTSSVSSGYGSGSGYGGGLGGGLGGGLGGGLAGGSSGSYYSSSSGGVGLGGGLSVGGSG 552

Query: 462 ASRRSAR 468
            S  S R
Sbjct: 553 FSASSGR 559


>gi|153791158 keratin 75 [Homo sapiens]
          Length = 551

 Score =  523 bits (1346), Expect = e-148
 Identities = 299/487 (61%), Positives = 355/487 (72%), Gaps = 49/487 (10%)

Query: 7   SPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSA------------ 54
           S V  +RSAA  G G   R+SSA     GS SLY LG ++ RV++               
Sbjct: 33  SSVSVARSAA--GSGGLGRISSAG-ASFGSRSLYNLGGAK-RVSINGCGSSCRSGFGGRA 88

Query: 55  -----------YGGPVGAG-------------IREVTINQSLLAPLRLDADPSLQRVRQE 90
                      YGG VG G             I+EVT+NQSLL PL L  DP++QRVR E
Sbjct: 89  SNRFGVNSGFGYGGGVGGGFSGPSFPVCPPGGIQEVTVNQSLLTPLHLQIDPTIQRVRAE 148

Query: 91  ESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAK-SSRLPDIFEAQIAGLR 149
           E EQIKTLNNKFASFIDKVRFLEQQNK+LETKW LLQEQ S      L  +F++  + LR
Sbjct: 149 EREQIKTLNNKFASFIDKVRFLEQQNKVLETKWALLQEQGSRTVRQNLEPLFDSYTSELR 208

Query: 150 GQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKV 209
            QLE++  + GRLEAELR+MQDVVEDFK +YEDEIN RTAAENEFV LKKDVDAAYM+KV
Sbjct: 209 RQLESITTERGRLEAELRNMQDVVEDFKVRYEDEINKRTAAENEFVALKKDVDAAYMNKV 268

Query: 210 ELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYE 269
           ELEAKV +L +EINF+ ++ + EL++LQ+Q+ DTSVVLSMDN+R+LDLD IIAEVKAQYE
Sbjct: 269 ELEAKVKSLPEEINFIHSVFDAELSQLQTQVGDTSVVLSMDNNRNLDLDSIIAEVKAQYE 328

Query: 270 EMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQR 329
           ++A  SRAEAE+WYQTK+E LQ  AG+HGDDLRNT+ EISEMNR IQRL+AEID++K Q 
Sbjct: 329 DIANRSRAEAESWYQTKYEELQVTAGRHGDDLRNTKQEISEMNRMIQRLRAEIDSVKKQC 388

Query: 330 AKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEI 389
           + L+ AIA+AE+RGELALKDARAK  +LE ALQ+ KQDMAR LREYQELM++KLALD+EI
Sbjct: 389 SSLQTAIADAEQRGELALKDARAKLVDLEEALQKAKQDMARLLREYQELMNIKLALDVEI 448

Query: 390 ATYRKLLEGEESRLAGDGVGAVNISVMNST-----GGSSSGGGIGLTLGGTMGSNALSFS 444
           ATYRKLLEGEE RL+G+GV  VNISV+ ST     G  SS GG  L LGG  G    SF+
Sbjct: 449 ATYRKLLEGEECRLSGEGVSPVNISVVTSTLSSGYGSGSSIGGGNLGLGGGSG---YSFT 505

Query: 445 SSAGPGL 451
           +S G  L
Sbjct: 506 TSGGHSL 512


>gi|5031839 keratin 6A [Homo sapiens]
          Length = 564

 Score =  519 bits (1337), Expect = e-147
 Identities = 285/449 (63%), Positives = 339/449 (75%), Gaps = 12/449 (2%)

Query: 14  SAAFSGRGAQVRLSSARPGGLGSSSLYGLGAS-----RPRVAVRSAYGGP-----VGAGI 63
           S A SG        S   GG GS   +G GA           +   +GGP        GI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 64  REVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKW 123
           +EVT+NQSLL PL L  DP++QRVR EE EQIKTLNNKFASFIDKVRFLEQQNK+LETKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPTIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLETKW 195

Query: 124 TLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYED 182
           TLLQEQ +      L  +FE  I  LR QL+++  + GRL++ELR MQD+VEDFKNKYED
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRGMQDLVEDFKNKYED 255

Query: 183 EINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISD 242
           EIN RTAAENEFV LKKDVDAAYM+KVEL+AK D L DEINFLR L + EL+++Q+ ISD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 243 TSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLR 302
           TSVVLSMDN+R+LDLD IIAEVKAQYEE+A+ SRAEAE+WYQTK+E LQ  AG+HGDDLR
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375

Query: 303 NTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQ 362
           NT+ EI+E+NR IQRL++EID++K Q A L+AAIA+AE+RGE+ALKDA+ K E LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 363 RGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGS 422
           + KQD+AR L+EYQELM+VKLALD+EIATYRKLLEGEE RL G+GVG VNISV+ ST  S
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495

Query: 423 SSGGGIGLTLG-GTMGSNALSFSSSAGPG 450
             GG  G+  G G  G ++ S+ S  G G
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVG 524


>gi|155969697 keratin 6C [Homo sapiens]
          Length = 564

 Score =  515 bits (1326), Expect = e-146
 Identities = 282/449 (62%), Positives = 339/449 (75%), Gaps = 12/449 (2%)

Query: 14  SAAFSGRGAQVRLSSARPGGLGSSSLYGLGAS-----RPRVAVRSAYGGP-----VGAGI 63
           S A SG        S   GG GS   +G GA           +   +GGP        GI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 64  REVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKW 123
           +EVT+NQSLL PL L  DP++QRVR EE EQIKTLNNKFASFIDKVRFLEQQNK+L+TKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKW 195

Query: 124 TLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYED 182
           TLLQEQ +      L  +FE  I  LR QL+++  + GRL++ELR+MQD+VED KNKYED
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDSIVGERGRLDSELRNMQDLVEDLKNKYED 255

Query: 183 EINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISD 242
           EIN RTAAENEFV LKKDVDAAYM+KVEL+AK D L DEINFLR L + EL+++Q+ ISD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 243 TSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLR 302
           TSVVLSMDN+R+LDLD IIAEVKAQYEE+A+ SRAEAE+WYQTK+E LQ  AG+HGDDLR
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQVTAGRHGDDLR 375

Query: 303 NTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQ 362
           NT+ EI+E+NR IQRL++EID++K Q A L+AAIA+AE+RGE+ALKDA+ K E LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCASLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 363 RGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGS 422
           + KQD+AR L+EYQELM+VKLALD+EIATYRKLLEGEE RL G+GVG VN+SV+ ST  S
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNVSVVQSTISS 495

Query: 423 SSGGGIGLTLG-GTMGSNALSFSSSAGPG 450
             GG  G+  G G  G ++ S+ S  G G
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGIG 524


>gi|119703753 keratin 6B [Homo sapiens]
          Length = 564

 Score =  514 bits (1325), Expect = e-146
 Identities = 283/449 (63%), Positives = 338/449 (75%), Gaps = 12/449 (2%)

Query: 14  SAAFSGRGAQVRLSSARPGGLGSSSLYGLGAS-----RPRVAVRSAYGGP-----VGAGI 63
           S A SG        S   GG GS   +G GA           +   +GGP        GI
Sbjct: 76  SCAISGGYGSRAGGSYGFGGAGSGFGFGGGAGIGFGLGGGAGLAGGFGGPGFPVCPPGGI 135

Query: 64  REVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKW 123
           +EVT+NQSLL PL L  DP++QRVR EE EQIKTLNNKFASFIDKVRFLEQQNK+L+TKW
Sbjct: 136 QEVTVNQSLLTPLNLQIDPAIQRVRAEEREQIKTLNNKFASFIDKVRFLEQQNKVLDTKW 195

Query: 124 TLLQEQKSAK-SSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYED 182
           TLLQEQ +      L  +FE  I  LR QL+ +  + GRL++ELR+MQD+VED KNKYED
Sbjct: 196 TLLQEQGTKTVRQNLEPLFEQYINNLRRQLDNIVGERGRLDSELRNMQDLVEDLKNKYED 255

Query: 183 EINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISD 242
           EIN RTAAENEFV LKKDVDAAYM+KVEL+AK D L DEINFLR L + EL+++Q+ ISD
Sbjct: 256 EINKRTAAENEFVTLKKDVDAAYMNKVELQAKADTLTDEINFLRALYDAELSQMQTHISD 315

Query: 243 TSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLR 302
           TSVVLSMDN+R+LDLD IIAEVKAQYEE+A+ SRAEAE+WYQTK+E LQ  AG+HGDDLR
Sbjct: 316 TSVVLSMDNNRNLDLDSIIAEVKAQYEEIAQRSRAEAESWYQTKYEELQITAGRHGDDLR 375

Query: 303 NTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQ 362
           NT+ EI+E+NR IQRL++EID++K Q A L+AAIA+AE+RGE+ALKDA+ K E LE ALQ
Sbjct: 376 NTKQEIAEINRMIQRLRSEIDHVKKQCANLQAAIADAEQRGEMALKDAKNKLEGLEDALQ 435

Query: 363 RGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGS 422
           + KQD+AR L+EYQELM+VKLALD+EIATYRKLLEGEE RL G+GVG VNISV+ ST  S
Sbjct: 436 KAKQDLARLLKEYQELMNVKLALDVEIATYRKLLEGEECRLNGEGVGQVNISVVQSTVSS 495

Query: 423 SSGGGIGLTLG-GTMGSNALSFSSSAGPG 450
             GG  G+  G G  G ++ S+ S  G G
Sbjct: 496 GYGGASGVGSGLGLGGGSSYSYGSGLGVG 524


>gi|4504919 keratin 8 [Homo sapiens]
          Length = 483

 Score =  509 bits (1310), Expect = e-144
 Identities = 292/450 (64%), Positives = 341/450 (75%), Gaps = 17/450 (3%)

Query: 6   SSPVFTSRSAAFSGRGAQVRLSSARPGG-LGSSSLYGLGASRPRVAVRSAYGGPVG-AGI 63
           S  V TS   AFS R       ++ PG  + SSS   +G+S  R  +   YGG  G  GI
Sbjct: 9   SYKVSTSGPRAFSSRSY-----TSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGI 63

Query: 64  REVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKW 123
             VT+NQSLL+PL L+ DP++Q VR +E EQIKTLNNKFASFIDKVRFLEQQNK+LETKW
Sbjct: 64  TAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKW 123

Query: 124 TLLQEQKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDE 183
           +LLQ+QK+A+S+ + ++FE+ I  LR QLE L  +  +LEAEL +MQ +VEDFKNKYEDE
Sbjct: 124 SLLQQQKTARSN-MDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDE 182

Query: 184 INHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDT 243
           IN RT  ENEFV++KKDVD AYM+KVELE++++ L DEINFLR L E E+ ELQSQISDT
Sbjct: 183 INKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDT 242

Query: 244 SVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRN 303
           SVVLSMDNSRSLD+D IIAEVKAQYE++A  SRAEAE+ YQ K+E LQ+ AGKHGDDLR 
Sbjct: 243 SVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRR 302

Query: 304 TRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQR 363
           T+ EISEMNR I RLQAEI+ +K QRA LEAAIA+AE+RGELA+KDA AK  ELEAALQR
Sbjct: 303 TKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQR 362

Query: 364 GKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNST---- 419
            KQDMARQLREYQELM+VKLALDIEIATYRKLLEGEESRL     G  N+S+   T    
Sbjct: 363 AKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLES---GMQNMSIHTKTTSGY 419

Query: 420 -GGSSSGGGIGLTLGGTMGSNALSFSSSAG 448
            GG SS  G GLT  G   S   SF S AG
Sbjct: 420 AGGLSSAYG-GLTSPGLSYSLGSSFGSGAG 448


>gi|109148552 keratin 3 [Homo sapiens]
          Length = 628

 Score =  488 bits (1256), Expect = e-138
 Identities = 265/425 (62%), Positives = 329/425 (77%), Gaps = 8/425 (1%)

Query: 31  PGGLGSSSLYGLGASRPRVAVRSAYG-GPVGAGIREVTINQSLLAPLRLDADPSLQRVRQ 89
           PGG G S  +G   S   +     +G G    GI+EVTINQSLL PL ++ DP + +V+ 
Sbjct: 140 PGGFGGSGGFGGPGS---LGSPGGFGPGGFPGGIQEVTINQSLLQPLNVEIDPQIGQVKA 196

Query: 90  EESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSS---RLPDIFEAQIA 146
           +E EQIKTLNNKFASFIDKVRFLEQQNK+LETKW LLQ+Q ++  S    L  +FE  I 
Sbjct: 197 QEREQIKTLNNKFASFIDKVRFLEQQNKVLETKWNLLQQQGTSSISGTNNLEPLFENHIN 256

Query: 147 GLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYM 206
            LR  L+ +  + GRL++EL++M+D+VEDFK KYEDEIN RTAAENEFV LKKDVD+AYM
Sbjct: 257 YLRSYLDNILGERGRLDSELKNMEDLVEDFKKKYEDEINKRTAAENEFVTLKKDVDSAYM 316

Query: 207 SKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKA 266
           +KVEL+AKVDAL DEI+FLRTL + EL+++QS ISDTSVVLSMDN+RSLDLD IIAEV+A
Sbjct: 317 NKVELQAKVDALIDEIDFLRTLYDAELSQMQSHISDTSVVLSMDNNRSLDLDSIIAEVRA 376

Query: 267 QYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIK 326
           QYE++A+ S+AEAEA YQTK   LQ  AG+HGDDLRNT++EI E+NR IQRL+AEI+ +K
Sbjct: 377 QYEDIAQRSKAEAEALYQTKLGELQTTAGRHGDDLRNTKSEIIELNRMIQRLRAEIEGVK 436

Query: 327 NQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALD 386
            Q A L+ AIAEAE+ GE+ALKDA AK +EL+AALQ+ K D+AR LR+YQELM+VKLALD
Sbjct: 437 KQNANLQTAIAEAEQHGEMALKDANAKLQELQAALQQAKDDLARLLRDYQELMNVKLALD 496

Query: 387 IEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSN-ALSFSS 445
           +EIATYRKLLEGEE R++G+   AV+ISV++S+  S+S GG G   GG MG      FS+
Sbjct: 497 VEIATYRKLLEGEEYRMSGECPSAVSISVVSSSTTSASAGGYGGGYGGGMGGGLGGGFSA 556

Query: 446 SAGPG 450
             G G
Sbjct: 557 GGGSG 561


>gi|109255249 keratin 4 [Homo sapiens]
          Length = 594

 Score =  486 bits (1250), Expect = e-137
 Identities = 271/463 (58%), Positives = 346/463 (74%), Gaps = 21/463 (4%)

Query: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSLYG-LGASRPRVAVRSAYGGP-----VGAGIRE 65
           ++S + S  G++        GG G+    G  G S       S  GGP        GI+E
Sbjct: 132 NKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSF------SGKGGPGFPVCPAGGIQE 185

Query: 66  VTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTL 125
           VTINQSLL PL ++ DP +Q+VR EE EQIK LNNKFASFIDKV+FLEQQNK+LETKW L
Sbjct: 186 VTINQSLLTPLHVEIDPEIQKVRTEEREQIKLLNNKFASFIDKVQFLEQQNKVLETKWNL 245

Query: 126 LQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEI 184
           LQ+Q +  SS+ L  +FE  ++ LR QL+ L  D GRL++EL++MQD VEDFK KYE+EI
Sbjct: 246 LQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVEDFKTKYEEEI 305

Query: 185 NHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTS 244
           N RTAAEN+FVVLKKDVDAAY++KVELEAKVD+LNDEINFL+ L + EL+++Q+ +SDTS
Sbjct: 306 NKRTAAENDFVVLKKDVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVSDTS 365

Query: 245 VVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNT 304
           VVLSMDN+R+LDLD IIAEV+AQYEE+A+ S+AEAEA YQTK + LQ    +HGD+L+NT
Sbjct: 366 VVLSMDNNRNLDLDSIIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHGDNLKNT 425

Query: 305 RNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRG 364
           ++EI+E+NR IQRL+AEI+NIK Q   L+ ++A+AE+RGE ALKDA +K+ ELEAALQ+ 
Sbjct: 426 KSEIAELNRMIQRLRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQA 485

Query: 365 KQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMN---STGG 421
           K+++AR LREYQELMSVKLALDIEIATYRKLLEGEE R++G+   AV+ISV++   STGG
Sbjct: 486 KEELARMLREYQELMSVKLALDIEIATYRKLLEGEEYRMSGECQSAVSISVVSGSTSTGG 545

Query: 422 SSSGGGIGLTLGGTMGSNALSFSSSAGPGLLKAYSIRTASASR 464
            S G G G   G + G     F S +G G     S+  +S+S+
Sbjct: 546 ISGGLGSGSGFGLSSG-----FGSGSGSGFGFGGSVSGSSSSK 583



 Score = 31.2 bits (69), Expect = 2.1
 Identities = 17/44 (38%), Positives = 22/44 (50%)

Query: 407 GVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSAGPG 450
           G  ++++SV  S  G+  GG  G   GG  G    SFS   GPG
Sbjct: 131 GNKSISMSVAGSRQGACFGGAGGFGTGGFGGGFGGSFSGKGGPG 174


>gi|32567786 keratin 6L [Homo sapiens]
          Length = 535

 Score =  479 bits (1234), Expect = e-135
 Identities = 274/496 (55%), Positives = 348/496 (70%), Gaps = 43/496 (8%)

Query: 7   SPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVG------ 60
           S V  SRS+  SG GA     +   GG GS SLY LG  +  ++V  A G  +G      
Sbjct: 34  SSVTVSRSSG-SGGGAHCGPGT---GGFGSRSLYNLGGHKS-ISVSVAGGALLGRALGGF 88

Query: 61  -----------------------AGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKT 97
                                   GI+EVT+NQSLL PL ++ DP +QRVR +E EQIKT
Sbjct: 89  GFGSRAFMGQGAGRQTFGPACPPGGIQEVTVNQSLLTPLHVEIDPEIQRVRTQEREQIKT 148

Query: 98  LNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKS---AKSSRLPDIFEAQIAGLRGQLEA 154
           LNNKFASFIDKVRFLEQQNK+LETKW LLQEQ        + L  +FEA +  +R  L+ 
Sbjct: 149 LNNKFASFIDKVRFLEQQNKVLETKWALLQEQGQNLGVTRNNLEPLFEAYLGSMRSTLDR 208

Query: 155 LQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAK 214
           LQ + GRL++ELR++QD+VEDFKNKYEDEIN  TAAENEFVVLKKDVDAAYM +++L  K
Sbjct: 209 LQSERGRLDSELRNVQDLVEDFKNKYEDEINKHTAAENEFVVLKKDVDAAYMGRMDLHGK 268

Query: 215 VDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKC 274
           V  L  EI+FL+ L E EL+++Q+ +S+T+VVLSMDN+R+LDLD IIAEVKAQYE +A+ 
Sbjct: 269 VGTLTQEIDFLQQLYEMELSQVQTHVSNTNVVLSMDNNRNLDLDSIIAEVKAQYELIAQR 328

Query: 275 SRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEA 334
           SRAEAEAWYQTK+E LQ  AGKHGD+LR+T+NEI+E+ R IQRLQ E D  K Q  +L+ 
Sbjct: 329 SRAEAEAWYQTKYEELQVTAGKHGDNLRDTKNEIAELTRTIQRLQGEADAAKKQCQQLQT 388

Query: 335 AIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRK 394
           AIAEAE+RGELALKDA+ K  +L+ AL + K+D+ R LR+YQELM+VKLALD+EIATYRK
Sbjct: 389 AIAEAEQRGELALKDAQKKLGDLDVALHQAKEDLTRLLRDYQELMNVKLALDVEIATYRK 448

Query: 395 LLEGEESRLAGDGVGAVNISVM-NST----GGSSSGGGIGLTLGGTMGSNALSFSSSAGP 449
           LLE EESR++G+   AV+ISV  NST    GG++S GG G++LGG+ G+    FS++ G 
Sbjct: 449 LLESEESRMSGECPSAVSISVTGNSTTVCGGGAASFGG-GISLGGSGGATKGGFSTNVGY 507

Query: 450 GLLKAYSIRTASASRR 465
             +K   +   ++  R
Sbjct: 508 STVKGGPVSAGTSILR 523


>gi|153791670 keratin 76 [Homo sapiens]
          Length = 638

 Score =  478 bits (1230), Expect = e-135
 Identities = 274/491 (55%), Positives = 340/491 (69%), Gaps = 42/491 (8%)

Query: 2   SIHFSSPVFTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASR--------------- 46
           SI  S    +SR+  F G  +    +    GG G S   G G  R               
Sbjct: 66  SISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFGGGRGVGSGFGGAGGFGGA 125

Query: 47  -----PRV-AVRSAYGGPVG-------AGIREVTINQSLLAPLRLDADPSLQRVRQEESE 93
                P V     ++GGP G        GI+EV +NQSLL PL ++ DP + +V+ +E E
Sbjct: 126 GGFGGPGVFGGPGSFGGPGGFGPGGFPGGIQEVIVNQSLLQPLNVEIDPQIGQVKAQERE 185

Query: 94  QIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKS-SRLPDIFEAQIAGLRGQL 152
           QIKTLNNKFASFIDKVRFLEQQNK+LETKW LLQ+Q +    S L   FE+ I+ L  QL
Sbjct: 186 QIKTLNNKFASFIDKVRFLEQQNKVLETKWELLQQQTTGSGPSSLEPCFESYISFLCKQL 245

Query: 153 EALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELE 212
           ++L  + G LE EL+SMQD+VEDFK KYEDEIN RTAAENEFV LKKDVDAA+M+KVEL+
Sbjct: 246 DSLLGERGNLEGELKSMQDLVEDFKKKYEDEINKRTAAENEFVGLKKDVDAAFMNKVELQ 305

Query: 213 AKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMA 272
           AKVD+L DE++FLRTL E EL+++QS  SDTSVVLSMDN+R LDL  IIAEV+AQYEE+A
Sbjct: 306 AKVDSLTDEVSFLRTLYEMELSQMQSHASDTSVVLSMDNNRCLDLGSIIAEVRAQYEEIA 365

Query: 273 KCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKL 332
           + S++EAEA YQTK   LQ  AG+HGDDLRNT++EI E+NR IQRL+AEI+N+K Q A L
Sbjct: 366 QRSKSEAEALYQTKLGELQTTAGRHGDDLRNTKSEIMELNRMIQRLRAEIENVKKQNANL 425

Query: 333 EAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATY 392
           + AIAEAE+RGE+ALKDA AK ++L+ ALQ+ K D+AR LR+YQELM+VKLALD+EIATY
Sbjct: 426 QTAIAEAEQRGEMALKDANAKLQDLQTALQKAKDDLARLLRDYQELMNVKLALDVEIATY 485

Query: 393 RKLLEGEESRLAGDGVGAVNISVMN---STGGSS----------SGGGIGLTLGGTMGSN 439
           RKLLEGEE R++G+   AV ISV++   ST GSS          SG G G   GG+  S+
Sbjct: 486 RKLLEGEECRMSGECQSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSS 545

Query: 440 ALSFSSSAGPG 450
           +  +  S G G
Sbjct: 546 SSGYGVSGGSG 556



 Score = 31.6 bits (70), Expect = 1.6
 Identities = 28/75 (37%), Positives = 33/75 (44%), Gaps = 22/75 (29%)

Query: 10 FTSRSAAFSGRGAQVRLSS-----ARPGG--------------LGSSSLYGLGASRP--- 47
          F+ RS  FSGR A V  SS     AR GG               GS SLY LG+++    
Sbjct: 10 FSGRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRSGAGSFGSRSLYNLGSNKSISI 69

Query: 48 RVAVRSAYGGPVGAG 62
           VA  S+  G  G G
Sbjct: 70 SVAAGSSRAGGFGGG 84


>gi|28173564 keratin 73 [Homo sapiens]
          Length = 540

 Score =  473 bits (1216), Expect = e-133
 Identities = 259/442 (58%), Positives = 329/442 (74%), Gaps = 17/442 (3%)

Query: 10  FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGG-----------P 58
           F+SRS    G    +  + A   G G +  YG G  R      S +G            P
Sbjct: 43  FSSRSLYSLGGARSISFNVA--SGSGWAGGYGFGRGRASGFAGSMFGSVALGSVCPSLCP 100

Query: 59  VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKL 118
            G GI +VTIN+SLLAPL ++ DP +Q+VR +E EQIK LNNKFASFIDKVRFLEQQN++
Sbjct: 101 PG-GIHQVTINKSLLAPLNVELDPEIQKVRAQEREQIKVLNNKFASFIDKVRFLEQQNQV 159

Query: 119 LETKWTLLQE-QKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFK 177
           LETKW LLQ+   +   + L  I E  I+ LR QLE L  D  RL++ELRS+++VVED+K
Sbjct: 160 LETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRSVREVVEDYK 219

Query: 178 NKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQ 237
            +YE+EIN RT AENEFVVLKKDVDAAY SKVEL+AKVDAL+ EI F + L E E  ++Q
Sbjct: 220 KRYEEEINKRTTAENEFVVLKKDVDAAYTSKVELQAKVDALDGEIKFFKCLYEGETAQIQ 279

Query: 238 SQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKH 297
           S ISDTS++LSMDN+R+LDLD IIAEV+AQYEE+A+ S+AEAEA YQTKF+ LQ  AG+H
Sbjct: 280 SHISDTSIILSMDNNRNLDLDSIIAEVRAQYEEIARKSKAEAEALYQTKFQELQLAAGRH 339

Query: 298 GDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEEL 357
           GDDL++T+NEISE+ R IQRL++EI+++K Q A LE AIA+AE+RG+ ALKDARAK +EL
Sbjct: 340 GDDLKHTKNEISELTRLIQRLRSEIESVKKQCANLETAIADAEQRGDCALKDARAKLDEL 399

Query: 358 EAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMN 417
           E ALQ+ K+++AR LREYQEL+SVKL+LDIEIATYRKLLEGEE R++G+   +V+ISV+N
Sbjct: 400 EGALQQAKEELARMLREYQELLSVKLSLDIEIATYRKLLEGEECRMSGEYTNSVSISVIN 459

Query: 418 ST--GGSSSGGGIGLTLGGTMG 437
           S+  G + +G G G +  GT G
Sbjct: 460 SSMAGMAGTGAGFGFSNAGTYG 481


>gi|15431316 keratin, hair, basic, 4 [Homo sapiens]
          Length = 600

 Score =  468 bits (1203), Expect = e-132
 Identities = 259/430 (60%), Positives = 313/430 (72%), Gaps = 4/430 (0%)

Query: 19  GRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVR-SAYGGPVGAGIREVTINQSLLAPLR 77
           G G   R  S    G G+ S  G G   P    R    G P    I  VT+N+SLL PL 
Sbjct: 92  GVGLGPRADSCVGLGFGAGSGIGYGFGGPGFGYRVGGVGVPAAPSITAVTVNKSLLTPLN 151

Query: 78  LDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRL 137
           L+ DP+ QRV+++E EQIKTLNNKFASFIDKVRFLEQQNKLLETKW+ LQEQK  +S+  
Sbjct: 152 LEIDPNAQRVKKDEKEQIKTLNNKFASFIDKVRFLEQQNKLLETKWSFLQEQKCIRSNLE 211

Query: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197
           P +FE+ I  LR QLE L  D  RL+AE   +QDV+E FK KYE+E+  R  AENEFV L
Sbjct: 212 P-LFESYITNLRRQLEVLVSDQARLQAERNHLQDVLEGFKKKYEEEVVCRANAENEFVAL 270

Query: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257
           KKDVDAA+M+K +LEA VD L  EI+FL+TL   E+  LQS IS+TSV++ MDNSR L+L
Sbjct: 271 KKDVDAAFMNKSDLEANVDTLTQEIDFLKTLYMEEIQLLQSHISETSVIVKMDNSRDLNL 330

Query: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317
           DGIIAEVKAQYEE+A+ SRA+AEAWYQTK+E +Q  AG+H D+LRN RNEI+E+ R IQR
Sbjct: 331 DGIIAEVKAQYEEVARRSRADAEAWYQTKYEEMQVTAGQHCDNLRNIRNEINELTRLIQR 390

Query: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377
           L+AEI++ K QRAKLEAA+AEAE++GE  L DA+ K  +LE ALQ+ KQDMARQL EYQE
Sbjct: 391 LKAEIEHAKAQRAKLEAAVAEAEQQGEATLSDAKCKLADLECALQQAKQDMARQLCEYQE 450

Query: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437
           LM+ KL LDIEIATYR+LLEGEESRL  +GVG VNISV +S GG   G    L  G T+ 
Sbjct: 451 LMNAKLGLDIEIATYRRLLEGEESRLC-EGVGPVNISVSSSRGGLVCGPE-PLVAGSTLS 508

Query: 438 SNALSFSSSA 447
              ++FS S+
Sbjct: 509 RGGVTFSGSS 518


>gi|28372503 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  466 bits (1199), Expect = e-131
 Identities = 258/439 (58%), Positives = 326/439 (74%), Gaps = 17/439 (3%)

Query: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSL--YGLGASRPRVAVRSAYGGPVGAGIREVTIN 69
           SRS A S   A  R    R GG   ++    GLG   P V        P G GI +VT+N
Sbjct: 55  SRSLALS---AAARRGGGRLGGFVGTAFGSAGLGPKCPSVC-------PPG-GIPQVTVN 103

Query: 70  QSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129
           +SLLAPL ++ DP +QRVR +E EQIK LNNKFASFIDKVRFLEQQN++LETKW LLQ+ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 130 KSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRT 188
                 + L  I+E  I+ L+ QLE L  DG RL++ELR+MQD+VED+K +YE EIN RT
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 189 AAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLS 248
           AAENEFVVLKKDVDAAYM+KVEL+AKVD+L DEI F + L E E+T++QS ISDTS+VLS
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 249 MDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEI 308
           MDN+R LDLD IIAEV+AQYEE+A  S+AEAE  YQTK + LQ  AG+HGDDL+ T+ EI
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEI 343

Query: 309 SEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDM 368
           SE+NR IQR+++EI N+K Q A LE AIA+AE+RG+ ALKDARAK +ELE AL + K+++
Sbjct: 344 SELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEEL 403

Query: 369 ARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGI 428
           AR LREYQEL+S+KLALD+EIATYRKLLE EE R++G+   +V+ISV++ST   + G G 
Sbjct: 404 ARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF 463

Query: 429 GLTLGGTMGSNALSFSSSA 447
            +  G    S++ S+ ++A
Sbjct: 464 SMGFG---ASSSYSYKTAA 479


>gi|226246663 keratin 72 isoform 1 [Homo sapiens]
          Length = 511

 Score =  466 bits (1199), Expect = e-131
 Identities = 258/439 (58%), Positives = 326/439 (74%), Gaps = 17/439 (3%)

Query: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSL--YGLGASRPRVAVRSAYGGPVGAGIREVTIN 69
           SRS A S   A  R    R GG   ++    GLG   P V        P G GI +VT+N
Sbjct: 55  SRSLALS---AAARRGGGRLGGFVGTAFGSAGLGPKCPSVC-------PPG-GIPQVTVN 103

Query: 70  QSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129
           +SLLAPL ++ DP +QRVR +E EQIK LNNKFASFIDKVRFLEQQN++LETKW LLQ+ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 130 KSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRT 188
                 + L  I+E  I+ L+ QLE L  DG RL++ELR+MQD+VED+K +YE EIN RT
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 189 AAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLS 248
           AAENEFVVLKKDVDAAYM+KVEL+AKVD+L DEI F + L E E+T++QS ISDTS+VLS
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 249 MDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEI 308
           MDN+R LDLD IIAEV+AQYEE+A  S+AEAE  YQTK + LQ  AG+HGDDL+ T+ EI
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKIQELQVTAGQHGDDLKLTKAEI 343

Query: 309 SEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDM 368
           SE+NR IQR+++EI N+K Q A LE AIA+AE+RG+ ALKDARAK +ELE AL + K+++
Sbjct: 344 SELNRLIQRIRSEIGNVKKQCADLETAIADAEQRGDCALKDARAKLDELEGALHQAKEEL 403

Query: 369 ARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGI 428
           AR LREYQEL+S+KLALD+EIATYRKLLE EE R++G+   +V+ISV++ST   + G G 
Sbjct: 404 ARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGGAGF 463

Query: 429 GLTLGGTMGSNALSFSSSA 447
            +  G    S++ S+ ++A
Sbjct: 464 SMGFG---ASSSYSYKTAA 479


>gi|15618995 keratin 71 [Homo sapiens]
          Length = 523

 Score =  459 bits (1182), Expect = e-129
 Identities = 252/443 (56%), Positives = 327/443 (73%), Gaps = 16/443 (3%)

Query: 10  FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYG----GPV------ 59
           F SRS    G    + ++S    G G S  YG G  R      S +G    GPV      
Sbjct: 43  FGSRSLYSLGGVRSLNVAS----GSGKSGGYGFGRGRASGFAGSMFGSVALGPVCPTVCP 98

Query: 60  GAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLL 119
             GI +VT+N+SLLAPL ++ DP +Q+VR +E EQIK LNNKFASFIDKVRFLEQQN++L
Sbjct: 99  PGGIHQVTVNESLLAPLNVELDPEIQKVRAQEREQIKALNNKFASFIDKVRFLEQQNQVL 158

Query: 120 ETKWTLLQE-QKSAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKN 178
           ETKW LLQ+   +   + L  I E  I+ LR QLE L  D  RL++ELR+++DVVED+K 
Sbjct: 159 ETKWELLQQLDLNNCKNNLEPILEGYISNLRKQLETLSGDRVRLDSELRNVRDVVEDYKK 218

Query: 179 KYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQS 238
           +YE+EIN RTAAENEFV+LKKDVDAAY +KVEL+AKV++++ EI F R L E E+T++QS
Sbjct: 219 RYEEEINKRTAAENEFVLLKKDVDAAYANKVELQAKVESMDQEIKFFRCLFEAEITQIQS 278

Query: 239 QISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHG 298
            ISD SV+LSMDN+R+LDLD II EV+ QYEE+A  S+AEAEA YQTKF+ LQ  AG+HG
Sbjct: 279 HISDMSVILSMDNNRNLDLDSIIDEVRTQYEEIALKSKAEAEALYQTKFQELQLAAGRHG 338

Query: 299 DDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELE 358
           DDL+NT+NEISE+ R IQR+++EI+N+K Q + LE AIA+AE+RG+ ALKDARAK +ELE
Sbjct: 339 DDLKNTKNEISELTRLIQRIRSEIENVKKQASNLETAIADAEQRGDNALKDARAKLDELE 398

Query: 359 AALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNS 418
            AL + K+++AR LREYQELMS+KLALD+EIATYRKLLE EE R++G+    V+IS+++S
Sbjct: 399 GALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLESEECRMSGEFPSPVSISIISS 458

Query: 419 T-GGSSSGGGIGLTLGGTMGSNA 440
           T GGS  G    +  GG + +++
Sbjct: 459 TSGGSVYGFRPSMVSGGYVANSS 481


>gi|119395750 keratin 1 [Homo sapiens]
          Length = 644

 Score =  452 bits (1164), Expect = e-127
 Identities = 243/435 (55%), Positives = 322/435 (74%), Gaps = 16/435 (3%)

Query: 32  GGLGSSSLYGLGASRPRVAVRS----AYGGPVG-----AGIREVTINQSLLAPLRLDADP 82
           GG+G     G G+              YGG  G      GI+EVTINQSLL PL ++ DP
Sbjct: 112 GGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVCPPGGIQEVTINQSLLQPLNVEIDP 171

Query: 83  SLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQE-QKSAKSSRLPDIF 141
            +Q+V+  E EQIK+LNN+FASFIDKVRFLEQQN++L+TKW LLQ+   S ++  L   F
Sbjct: 172 EIQKVKSREREQIKSLNNQFASFIDKVRFLEQQNQVLQTKWELLQQVDTSTRTHNLEPYF 231

Query: 142 EAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDV 201
           E+ I  LR +++ L+ D  RL++EL++MQD+VED++NKYEDEIN RT AENEFV +KKDV
Sbjct: 232 ESFINNLRRRVDQLKSDQSRLDSELKNMQDMVEDYRNKYEDEINKRTNAENEFVTIKKDV 291

Query: 202 DAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGII 261
           D AYM+KV+L+AK+D L  EI+FL  L + EL+++Q+QIS+T+V+LSMDN+RSLDLD II
Sbjct: 292 DGAYMTKVDLQAKLDNLQQEIDFLTALYQAELSQMQTQISETNVILSMDNNRSLDLDSII 351

Query: 262 AEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAE 321
           AEVKAQYE++A+ S+AEAE+ YQ+K+E LQ  AG+HGD +RN++ EISE+NR IQRL++E
Sbjct: 352 AEVKAQYEDIAQKSKAEAESLYQSKYEELQITAGRHGDSVRNSKIEISELNRVIQRLRSE 411

Query: 322 IDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSV 381
           IDN+K Q + L+ +I++AE+RGE ALKDA+ K  +LE ALQ+ K+D+AR LR+YQELM+ 
Sbjct: 412 IDNVKKQISNLQQSISDAEQRGENALKDAKNKLNDLEDALQQAKEDLARLLRDYQELMNT 471

Query: 382 KLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMN-----STGGSSSGGGIGLTLGG-T 435
           KLALD+EIATYR LLEGEESR++G+    V++SV       S GGS  GGG G   GG +
Sbjct: 472 KLALDLEIATYRTLLEGEESRMSGECAPNVSVSVSTSHTTISGGGSRGGGGGGYGSGGSS 531

Query: 436 MGSNALSFSSSAGPG 450
            GS   S+ S  G G
Sbjct: 532 YGSGGGSYGSGGGGG 546


>gi|148612803 keratin 6 irs4 [Homo sapiens]
          Length = 529

 Score =  441 bits (1135), Expect = e-124
 Identities = 246/448 (54%), Positives = 316/448 (70%), Gaps = 18/448 (4%)

Query: 10  FTSRSAAFSGRGAQVRLSSA----RPGGLGSSSLYGLGASRPRVAVRSAYG----GPV-- 59
           F SRS    G   ++  + A    R GG G     G G  R      S +G    GP   
Sbjct: 45  FGSRSLYSLGGNRRISFNVAGGGVRAGGYGFRPGSGYGGGRASGFAGSMFGSVALGPACL 104

Query: 60  ----GAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQ 115
                 GI +VT+N+SLLAPL ++ DP +Q+VR +E EQIK LN+KFASFIDKVRFLEQQ
Sbjct: 105 SVCPPGGIHQVTVNKSLLAPLNVELDPEIQKVRAQEREQIKVLNDKFASFIDKVRFLEQQ 164

Query: 116 NKLLETKWTLLQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVE 174
           N++LETKW LLQ+       + L  I E  I+ LR QLE L  D  RL++ELRSM+D+VE
Sbjct: 165 NQVLETKWELLQQLDLNNCKKNLEPILEGYISNLRKQLETLSGDRVRLDSELRSMRDLVE 224

Query: 175 DFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELT 234
           D+K +YE EIN RT AENEFVVLKKD DAAY  KVEL+AKVD+L+ EI FL+ L + E+ 
Sbjct: 225 DYKKRYEVEINRRTTAENEFVVLKKDADAAYAVKVELQAKVDSLDKEIKFLKCLYDAEIA 284

Query: 235 ELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQA 294
           ++Q+  S+TSV+LSMDN+R LDLD IIAEV+  YEE+A  S+AEAEA YQTK + LQ  A
Sbjct: 285 QIQTHASETSVILSMDNNRDLDLDSIIAEVRMHYEEIALKSKAEAEALYQTKIQELQLAA 344

Query: 295 GKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQ 354
            +HGDDL++TR+E+ E+NR IQR++ EI N+K QRA LE AIA+AE+RG+ ALKDA+AK 
Sbjct: 345 SRHGDDLKHTRSEMVELNRLIQRIRCEIGNVKKQRASLETAIADAEQRGDNALKDAQAKL 404

Query: 355 EELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNIS 414
           +ELE AL + K+++AR LREYQELMS+KLALD+EIATYRKLLEGEE R++G+   +V+IS
Sbjct: 405 DELEGALHQAKEELARMLREYQELMSLKLALDMEIATYRKLLEGEECRMSGENPSSVSIS 464

Query: 415 VMNSTGGS---SSGGGIGLTLGGTMGSN 439
           V++S+  S    S  G+ L      GS+
Sbjct: 465 VISSSSYSYHHPSSAGVDLGASAVAGSS 492


>gi|194018511 keratin 77 [Homo sapiens]
          Length = 578

 Score =  436 bits (1121), Expect = e-122
 Identities = 238/438 (54%), Positives = 315/438 (71%), Gaps = 7/438 (1%)

Query: 19  GRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVGAGIREVTINQSLLAPLRL 78
           GRG  V  + A   G G     G G S   +     Y  P   GI+EVTINQSLL PL L
Sbjct: 94  GRGFGVGSTGAGGFGGGGFGGAGFGTSNFGLGGFGPYCPP--GGIQEVTINQSLLEPLHL 151

Query: 79  DADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQE-QKSAKSSRL 137
           + DP +QR++ +E EQI  LNNKFASFIDKVRFLEQQN++L+TKW LLQ+   S  ++ L
Sbjct: 152 EVDPEIQRIKTQEREQIMVLNNKFASFIDKVRFLEQQNQVLQTKWELLQQVNTSTGTNNL 211

Query: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197
             + E  I  LR Q++ L  +  R  AE+RSMQDVVED+K+KYEDEIN RT +EN+FVVL
Sbjct: 212 EPLLENYIGDLRRQVDLLSAEQMRQNAEVRSMQDVVEDYKSKYEDEINKRTGSENDFVVL 271

Query: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257
           KKDVDAAY+SKV+LE++VD L  E+NFL+ L  TEL+++Q+ ISDT+V+LSMDN+RSLDL
Sbjct: 272 KKDVDAAYVSKVDLESRVDTLTGEVNFLKYLFLTELSQVQTHISDTNVILSMDNNRSLDL 331

Query: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317
           D II  V+ QYE +A+ S+ EAEA YQTK++ LQ  AG+HGDDL+N++ EI+E+NR +QR
Sbjct: 332 DSIIDAVRTQYELIAQRSKDEAEALYQTKYQELQITAGRHGDDLKNSKMEIAELNRTVQR 391

Query: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377
           LQAEI N+K Q  ++++ I++AEERGE AL+DA  K ++LE ALQ+ K+++AR LR+YQ 
Sbjct: 392 LQAEISNVKKQIEQMQSLISDAEERGEQALQDAWQKLQDLEEALQQSKEELARLLRDYQA 451

Query: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437
           ++ VKL+LD+EIATYR+LLEGEESR++G+    V+ISV NS    + G G     GG+ G
Sbjct: 452 MLGVKLSLDVEIATYRQLLEGEESRMSGELQSHVSISVQNSQVSVNGGAG----GGGSYG 507

Query: 438 SNALSFSSSAGPGLLKAY 455
           S      S  G G  ++Y
Sbjct: 508 SGGYGGGSGGGYGGGRSY 525


>gi|47132620 keratin 2 [Homo sapiens]
          Length = 639

 Score =  430 bits (1106), Expect = e-120
 Identities = 240/457 (52%), Positives = 306/457 (66%), Gaps = 26/457 (5%)

Query: 14  SAAFSGRGAQVRLSSARPGGLGSSSLYGLGASRPRVAVRSAYGGPVGAG----------- 62
           +  F GRG      S+  GG G S   G G           +GGP G G           
Sbjct: 86  AGGFGGRGGGFGGGSSFGGGSGFSG-GGFGGGGFGGGRFGGFGGPGGVGGLGGPGGFGPG 144

Query: 63  -----IREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNK 117
                I EV++NQSLL PL +  DP +Q V+ +E EQIKTLNNKFASFIDKVRFLEQQN+
Sbjct: 145 GYPGGIHEVSVNQSLLQPLNVKVDPEIQNVKAQEREQIKTLNNKFASFIDKVRFLEQQNQ 204

Query: 118 LLETKWTLLQEQK-SAKSSRLPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDF 176
           +L+TKW LLQ+     +   L  IF+  I  L+  L+ L  +     +EL +MQD+VED+
Sbjct: 205 VLQTKWELLQQMNVGTRPINLEPIFQGYIDSLKRYLDGLTAERTSQNSELNNMQDLVEDY 264

Query: 177 KNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTEL 236
           K KYEDEIN RTAAEN+FV LKKDVD AYM KVEL++KVD LN EI FL+ L + E++++
Sbjct: 265 KKKYEDEINKRTAAENDFVTLKKDVDNAYMIKVELQSKVDLLNQEIEFLKVLYDAEISQI 324

Query: 237 QSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGK 296
              ++DT+V+LSMDNSR+LDLD IIAEVKAQYEE+A+ S+ EAEA Y +K+E LQ   G+
Sbjct: 325 HQSVTDTNVILSMDNSRNLDLDSIIAEVKAQYEEIAQRSKEEAEALYHSKYEELQVTVGR 384

Query: 297 HGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEE 356
           HGD L+  + EISE+NR IQRLQ EI ++K Q   ++ AIA+AE+RGE ALKDAR K  +
Sbjct: 385 HGDSLKEIKIEISELNRVIQRLQGEIAHVKKQCKNVQDAIADAEQRGEHALKDARNKLND 444

Query: 357 LEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVM 416
           LE ALQ+ K+D+AR LR+YQELM+VKLALD+EIATYRKLLEGEE R++GD    V +SV 
Sbjct: 445 LEEALQQAKEDLARLLRDYQELMNVKLALDVEIATYRKLLEGEECRMSGDLSSNVTVSVT 504

Query: 417 NSTGGSS--------SGGGIGLTLGGTMGSNALSFSS 445
           +ST  S+          GG G + GG   S + S+ S
Sbjct: 505 SSTISSNVASKAAFGGSGGRGSSSGGGYSSGSSSYGS 541



 Score = 29.3 bits (64), Expect = 8.0
 Identities = 19/41 (46%), Positives = 23/41 (56%), Gaps = 3/41 (7%)

Query: 409 GAVNISVMNSTGGSSSGGGIGLTLGGT---MGSNALSFSSS 446
           G  + S   S GGSSSGGG G   GG+    GS+  +F SS
Sbjct: 593 GGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSS 633


>gi|4504935 keratin 85 [Homo sapiens]
          Length = 507

 Score =  429 bits (1104), Expect = e-120
 Identities = 237/431 (54%), Positives = 303/431 (70%), Gaps = 20/431 (4%)

Query: 33  GLGSSSLYGLGASRPRVAVRSAYGGPVGAG---------------IREVTINQSLLAPLR 77
           G GS SL  LG+  PR+AV     G  G                 I  V++N+SLL PL 
Sbjct: 50  GFGSRSLCNLGSCGPRIAVGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLN 109

Query: 78  LDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRL 137
           L+ DP+ Q V+QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETKW   Q Q+  +S+  
Sbjct: 110 LEIDPNAQCVKQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKWQFYQNQRCCESNLE 169

Query: 138 PDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVL 197
           P +F   I  LR + E ++ D GRL +EL  +Q+V+E +K KYE+E+  R  AENEFVVL
Sbjct: 170 P-LFSGYIETLRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVVL 228

Query: 198 KKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDL 257
           KKDVD AY+ K +LEA V+AL +E +FLR L E E+  LQ+ ISDTSV++ MDNSR L++
Sbjct: 229 KKDVDCAYLRKSDLEANVEALVEESSFLRRLYEEEIRVLQAHISDTSVIVKMDNSRDLNM 288

Query: 258 DGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQR 317
           D IIAE+KAQY+++A  SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQR
Sbjct: 289 DCIIAEIKAQYDDVASRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQR 348

Query: 318 LQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQE 377
           L AEI+N K QRAKLEAA+AEAE++GE AL DAR K  ELE ALQ+ KQDMA  L+EYQE
Sbjct: 349 LTAEIENAKCQRAKLEAAVAEAEQQGEAALSDARCKLAELEGALQKAKQDMACLLKEYQE 408

Query: 378 LMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMG 437
           +M+ KL LDIEIATYR+LLEGEE RL  +GVG+VN+ V +S GG S G   GL+   T G
Sbjct: 409 VMNSKLGLDIEIATYRRLLEGEEHRLC-EGVGSVNVCVSSSRGGVSCG---GLSYSTTPG 464

Query: 438 SNALSFSSSAG 448
               S  S+ G
Sbjct: 465 RQITSGPSAIG 475


>gi|27477127 keratin 82 [Homo sapiens]
          Length = 513

 Score =  428 bits (1101), Expect = e-120
 Identities = 243/449 (54%), Positives = 309/449 (68%), Gaps = 31/449 (6%)

Query: 1   MSIHFSSPVFTSRSAAFSGRGA---------QVRLSSARPGG---------LGSSSLYGL 42
           MS H   P     S +FS   A          V     RPGG         LGS SL  +
Sbjct: 1   MSYHSFQPGSRCGSQSFSSYSAVMPRMVTHYAVSKGPCRPGGGRGLRALGCLGSRSLCNV 60

Query: 43  GASRPRVAVRSA-----YGGPVGAG------IREVTINQSLLAPLRLDADPSLQRVRQEE 91
           G  RPRVA R       +G  +GA       I  VTIN+SLL PL L+ DP++QRV+++E
Sbjct: 61  GFGRPRVASRCGGTLPGFGYRLGATCGPSACITPVTINESLLVPLALEIDPTVQRVKRDE 120

Query: 92  SEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAGLRGQ 151
            EQIK LNN+FASFI+KVRFLEQ+NKLLETKW  +Q+Q+  +++  P IFE  I+ LR Q
Sbjct: 121 KEQIKCLNNRFASFINKVRFLEQKNKLLETKWNFMQQQRCCQTNIEP-IFEGYISALRRQ 179

Query: 152 LEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVEL 211
           L+ +  D  RLE+EL S+Q  +E +K KYE+E++ R   ENEFV LKKDVD A++ K +L
Sbjct: 180 LDCVSGDRVRLESELCSLQAALEGYKKKYEEELSLRPCVENEFVALKKDVDTAFLMKADL 239

Query: 212 EAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEM 271
           E   +AL  EI+FL++L E E+  LQSQIS+TSV++ MDNSR LD+DGIIAE+KAQY+++
Sbjct: 240 ETNAEALVQEIDFLKSLYEEEICLLQSQISETSVIVKMDNSRELDVDGIIAEIKAQYDDI 299

Query: 272 AKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAK 331
           A  S+AEAEAWYQ ++E L+  AG H D+LRN +NEI EMN+ IQRLQ E +N+K QR K
Sbjct: 300 ASRSKAEAEAWYQCRYEELRVTAGNHCDNLRNRKNEILEMNKLIQRLQQETENVKAQRCK 359

Query: 332 LEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIAT 391
           LE AIAEAE++GE AL DA+ K   LE ALQ+ KQDMA  L+EYQE+M+ KL LDIEIAT
Sbjct: 360 LEGAIAEAEQQGEAALNDAKCKLAGLEEALQKAKQDMACLLKEYQEVMNSKLGLDIEIAT 419

Query: 392 YRKLLEGEESRLAGDGVGAVNISVMNSTG 420
           YR+LLEGEE RL  +G+G VNISV +S G
Sbjct: 420 YRRLLEGEEHRLC-EGIGPVNISVSSSKG 447


>gi|89357932 keratin 5b [Homo sapiens]
          Length = 520

 Score =  420 bits (1080), Expect = e-117
 Identities = 237/448 (52%), Positives = 317/448 (70%), Gaps = 23/448 (5%)

Query: 10  FTSRSAAFSGRGAQVRLSSARPGGLGSSSLYGLGA-----------SRPRVAVRSAY--G 56
           F++RSA  +    + R   +  GG  S SL   G            S  R+ VR     G
Sbjct: 12  FSARSACSARSRGRSRGGFSSRGGFSSRSLNSFGGCLEGSRGSTWGSGGRLGVRFGEWSG 71

Query: 57  GP-----VGAGIREVTINQSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRF 111
           GP        GI+EVTINQ+LL PL+++ DP  Q VR +E+++I+TLNN+FASFIDKVRF
Sbjct: 72  GPGLSLCPPGGIQEVTINQNLLTPLKIEIDPQFQVVRTQETQEIRTLNNQFASFIDKVRF 131

Query: 112 LEQQNKLLETKWTLLQEQKSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQ 170
           LEQQNK+LETKW LLQ+Q  + S + L  +FEA +  LR QLE LQ + G L+AEL++ +
Sbjct: 132 LEQQNKVLETKWHLLQQQGLSGSQQGLEPVFEACLDQLRKQLEQLQGERGALDAELKACR 191

Query: 171 DVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNE 230
           D  E++K+KYE+E + R   EN+FVVLKKDVD  ++SK+ELE K++AL + + FL+ LNE
Sbjct: 192 DQEEEYKSKYEEEAHRRATLENDFVVLKKDVDGVFLSKMELEGKLEALREYLYFLKHLNE 251

Query: 231 TELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTKFETL 290
            EL +LQ+Q SDTSVVLSMDN+R LD   II EV+A+YEE+A+ S+AEAEA YQTK++ L
Sbjct: 252 EELGQLQTQASDTSVVLSMDNNRYLDFSSIITEVRARYEEIARSSKAEAEALYQTKYQEL 311

Query: 291 QAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDA 350
           Q  A  HGD ++ T+ +IS++++ IQRLQ++ +N+K Q A L+AAI +AE+RGELALKDA
Sbjct: 312 QVSAQLHGDRMQETKVQISQLHQEIQRLQSQTENLKKQNASLQAAITDAEQRGELALKDA 371

Query: 351 RAKQEELEAALQRGKQDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGA 410
           +AK +ELEAAL+  KQ++AR L EYQEL S KL+LD+EIATYR+LLEGEE R++G+    
Sbjct: 372 QAKVDELEAALRMAKQNLARLLCEYQELTSTKLSLDVEIATYRRLLEGEECRMSGECTSQ 431

Query: 411 VNISVMNSTGGSS-SGGGIGLTLGGTMG 437
           V IS   S GGS+   GG+G  LG T G
Sbjct: 432 VTIS---SVGGSAVMSGGVGGGLGSTCG 456


>gi|239755818 PREDICTED: hypothetical protein isoform 2 [Homo
           sapiens]
          Length = 486

 Score =  407 bits (1046), Expect = e-113
 Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447
           EIATYR+LLEGEE RL  +GVG+VN+ V +S GG   G     T    + +   S  S++
Sbjct: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460


>gi|239755816 PREDICTED: hypothetical protein isoform 1 [Homo
           sapiens]
          Length = 486

 Score =  407 bits (1046), Expect = e-113
 Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447
           EIATYR+LLEGEE RL  +GVG+VN+ V +S GG   G     T    + +   S  S++
Sbjct: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460


>gi|239755814 PREDICTED: hypothetical protein isoform 3 [Homo
           sapiens]
          Length = 486

 Score =  407 bits (1046), Expect = e-113
 Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447
           EIATYR+LLEGEE RL  +GVG+VN+ V +S GG   G     T    + +   S  S++
Sbjct: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460


>gi|14318422 keratin 86 [Homo sapiens]
          Length = 486

 Score =  407 bits (1046), Expect = e-113
 Identities = 224/420 (53%), Positives = 296/420 (70%), Gaps = 6/420 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEIRVLQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSGGGIGLTLGGTMGSNALSFSSSA 447
           EIATYR+LLEGEE RL  +GVG+VN+ V +S GG   G     T    + +   S  S++
Sbjct: 402 EIATYRRLLEGEEQRLC-EGVGSVNVCVSSSRGGVVCGDLCASTTAPVVSTRVSSVPSNS 460


>gi|169790853 keratin, hair, basic, 1 [Homo sapiens]
          Length = 505

 Score =  407 bits (1045), Expect = e-113
 Identities = 221/398 (55%), Positives = 289/398 (72%), Gaps = 6/398 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 43  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 102

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +FE  I  
Sbjct: 103 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFEGYIET 161

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E++ R  AENEFV LKKDVD AY+ 
Sbjct: 162 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVSLRATAENEFVALKKDVDCAYLR 221

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D IIAE+KAQ
Sbjct: 222 KSDLEANVEALIQEIDFLRRLYEEEILILQSHISDTSVVVKLDNSRDLNMDCIIAEIKAQ 281

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++   SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 282 YDDIVTRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 341

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 342 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 401

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425
           EIATYR+LLEGEE RL  +G+GAVN+ V +S GG   G
Sbjct: 402 EIATYRRLLEGEEQRLC-EGIGAVNVCVSSSRGGVVCG 438


>gi|169790841 keratin 83 [Homo sapiens]
          Length = 493

 Score =  402 bits (1032), Expect = e-112
 Identities = 220/398 (55%), Positives = 287/398 (72%), Gaps = 6/398 (1%)

Query: 32  GGLGSSSLYG---LGASRPRVAVRSA-YGGPVGAGIREVTINQSLLAPLRLDADPSLQRV 87
           GG GS S+ G    G+       RS    GP    I  V++N+SLL PL L+ DP+ Q V
Sbjct: 48  GGFGSHSVCGGFRAGSCGRSFGYRSGGVCGPSPPCITTVSVNESLLTPLNLEIDPNAQCV 107

Query: 88  RQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQKSAKSSRLPDIFEAQIAG 147
           +QEE EQIK+LN++FA+FIDKVRFLEQQNKLLETK    Q ++  +S+  P +F   I  
Sbjct: 108 KQEEKEQIKSLNSRFAAFIDKVRFLEQQNKLLETKLQFYQNRECCQSNLEP-LFAGYIET 166

Query: 148 LRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRTAAENEFVVLKKDVDAAYMS 207
           LR + E ++ D GRL +EL  +Q+V+E +K KYE+E+  R  AENEFV LKKDVD AY+ 
Sbjct: 167 LRREAECVEADSGRLASELNHVQEVLEGYKKKYEEEVALRATAENEFVALKKDVDCAYLR 226

Query: 208 KVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLSMDNSRSLDLDGIIAEVKAQ 267
           K +LEA V+AL  EI+FLR L E E+  LQS ISDTSVV+ +DNSR L++D I+AE+KAQ
Sbjct: 227 KSDLEANVEALIQEIDFLRRLYEEEIRILQSHISDTSVVVKLDNSRDLNMDCIVAEIKAQ 286

Query: 268 YEEMAKCSRAEAEAWYQTKFETLQAQAGKHGDDLRNTRNEISEMNRAIQRLQAEIDNIKN 327
           Y+++A  SRAEAE+WY++K E ++A   +HG+ LR T+ EI+E+NR IQRL AE++N K 
Sbjct: 287 YDDIATRSRAEAESWYRSKCEEMKATVIRHGETLRRTKEEINELNRMIQRLTAEVENAKC 346

Query: 328 QRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGKQDMARQLREYQELMSVKLALDI 387
           Q +KLEAA+A++E++GE AL DAR K  ELE ALQ+ KQDMA  +REYQE+M+ KL LDI
Sbjct: 347 QNSKLEAAVAQSEQQGEAALSDARCKLAELEGALQKAKQDMACLIREYQEVMNSKLGLDI 406

Query: 388 EIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425
           EIATYR+LLEGEE RL  +GV AVN+ V +S GG   G
Sbjct: 407 EIATYRRLLEGEEQRLC-EGVEAVNVCVSSSRGGVVCG 443


>gi|226246665 keratin 72 isoform 2 [Homo sapiens]
          Length = 469

 Score =  372 bits (954), Expect = e-103
 Identities = 227/442 (51%), Positives = 286/442 (64%), Gaps = 65/442 (14%)

Query: 12  SRSAAFSGRGAQVRLSSARPGGLGSSSL--YGLGASRPRVAVRSAYGGPVGAGIREVTIN 69
           SRS A S   A  R    R GG   ++    GLG   P V        P G GI +VT+N
Sbjct: 55  SRSLALS---AAARRGGGRLGGFVGTAFGSAGLGPKCPSVC-------PPG-GIPQVTVN 103

Query: 70  QSLLAPLRLDADPSLQRVRQEESEQIKTLNNKFASFIDKVRFLEQQNKLLETKWTLLQEQ 129
           +SLLAPL ++ DP +QRVR +E EQIK LNNKFASFIDKVRFLEQQN++LETKW LLQ+ 
Sbjct: 104 KSLLAPLNVEMDPEIQRVRAQEREQIKALNNKFASFIDKVRFLEQQNQVLETKWNLLQQL 163

Query: 130 KSAKSSR-LPDIFEAQIAGLRGQLEALQVDGGRLEAELRSMQDVVEDFKNKYEDEINHRT 188
                 + L  I+E  I+ L+ QLE L  DG RL++ELR+MQD+VED+K +YE EIN RT
Sbjct: 164 DLNNCRKNLEPIYEGYISNLQKQLEMLSGDGVRLDSELRNMQDLVEDYKKRYEVEINRRT 223

Query: 189 AAENEFVVLKKDVDAAYMSKVELEAKVDALNDEINFLRTLNETELTELQSQISDTSVVLS 248
           AAENEFVVLKKDVDAAYM+KVEL+AKVD+L DEI F + L E E+T++QS ISDTS+VLS
Sbjct: 224 AAENEFVVLKKDVDAAYMNKVELQAKVDSLTDEIKFFKCLYEGEITQIQSHISDTSIVLS 283

Query: 249 MDNSRSLDLDGIIAEVKAQYEEMAKCSRAEAEAWYQTK---FETLQAQAGKHGDDLRNTR 305
           MDN+R LDLD IIAEV+AQYEE+A  S+AEAE  YQTK    ET  A A + GD      
Sbjct: 284 MDNNRDLDLDSIIAEVRAQYEEIALKSKAEAETLYQTKCADLETAIADAEQRGDCA---- 339

Query: 306 NEISEMNRAIQRLQAEIDNIKNQRAKLEAAIAEAEERGELALKDARAKQEELEAALQRGK 365
                              +K+ RAKL                      +ELE AL + K
Sbjct: 340 -------------------LKDARAKL----------------------DELEGALHQAK 358

Query: 366 QDMARQLREYQELMSVKLALDIEIATYRKLLEGEESRLAGDGVGAVNISVMNSTGGSSSG 425
           +++AR LREYQEL+S+KLALD+EIATYRKLLE EE R++G+   +V+ISV++ST   + G
Sbjct: 359 EELARMLREYQELVSLKLALDMEIATYRKLLESEECRMSGEYPNSVSISVISSTNAGAGG 418

Query: 426 GGIGLTLGGTMGSNALSFSSSA 447
            G  +  G    S++ S+ ++A
Sbjct: 419 AGFSMGFG---ASSSYSYKTAA 437


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.128    0.336 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,292,488
Number of Sequences: 37866
Number of extensions: 607110
Number of successful extensions: 6113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 251
Number of HSP's successfully gapped in prelim test: 571
Number of HSP's that attempted gapping in prelim test: 3473
Number of HSP's gapped (non-prelim): 2077
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.