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Search of human proteins with 67782356
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|67782356 corneodesmosin precursor [Homo sapiens]
(529 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|67782356 corneodesmosin precursor [Homo sapiens] 1065 0.0
gi|57864582 hornerin [Homo sapiens] 98 2e-20
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 86 1e-16
gi|62122917 filaggrin family member 2 [Homo sapiens] 85 2e-16
gi|169658378 trinucleotide repeat containing 18 [Homo sapiens] 76 9e-14
gi|109255251 loricrin [Homo sapiens] 74 4e-13
gi|161016767 mucin 21 [Homo sapiens] 70 4e-12
gi|186928825 dermokine isoform 3 precursor [Homo sapiens] 69 1e-11
gi|186928827 dermokine isoform 5 precursor [Homo sapiens] 67 3e-11
gi|55956899 keratin 9 [Homo sapiens] 67 4e-11
gi|153791670 keratin 76 [Homo sapiens] 65 2e-10
gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1 ... 65 2e-10
gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3 ... 65 2e-10
gi|195972866 keratin 10 [Homo sapiens] 65 2e-10
gi|239743293 PREDICTED: mucin 12 [Homo sapiens] 64 3e-10
gi|186928829 dermokine isoform 4 precursor [Homo sapiens] 64 3e-10
gi|33504489 dermokine isoform 2 precursor [Homo sapiens] 64 3e-10
gi|28559039 mediator complex subunit 1 [Homo sapiens] 63 8e-10
gi|33946327 nucleoporin 214kDa [Homo sapiens] 62 1e-09
gi|119395750 keratin 1 [Homo sapiens] 62 2e-09
gi|18375613 dachshund homolog 1 isoform b [Homo sapiens] 62 2e-09
gi|18375611 dachshund homolog 1 isoform a [Homo sapiens] 62 2e-09
gi|18375609 dachshund homolog 1 isoform c [Homo sapiens] 62 2e-09
gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo ... 61 2e-09
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 60 5e-09
gi|47132620 keratin 2 [Homo sapiens] 60 6e-09
gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens] 60 6e-09
gi|239755326 PREDICTED: hypothetical protein [Homo sapiens] 59 8e-09
gi|169173184 PREDICTED: hypothetical protein [Homo sapiens] 58 2e-08
gi|60097902 filaggrin [Homo sapiens] 57 3e-08
>gi|67782356 corneodesmosin precursor [Homo sapiens]
Length = 529
Score = 1065 bits (2754), Expect = 0.0
Identities = 529/529 (100%), Positives = 529/529 (100%)
Query: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG
Sbjct: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG
Sbjct: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND
Sbjct: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
Query: 181 NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI 240
NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI
Sbjct: 181 NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI 240
Query: 241 PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG 300
PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG
Sbjct: 241 PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG 300
Query: 301 GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ 360
GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ
Sbjct: 301 GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ 360
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ 420
SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ
Sbjct: 361 SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ 420
Query: 421 SPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS 480
SPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS
Sbjct: 421 SPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS 480
Query: 481 AGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLNSP 529
AGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLNSP
Sbjct: 481 AGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEVFLPQGELLNSP 529
>gi|57864582 hornerin [Homo sapiens]
Length = 2850
Score = 98.2 bits (243), Expect = 2e-20
Identities = 142/467 (30%), Positives = 176/467 (37%), Gaps = 52/467 (11%)
Query: 46 TRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS-----SARSSGGGSSGSSSGSSIAQG 100
+R +S P G G SS Y S S + S +SSG G GSSSG S G
Sbjct: 552 SRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESRSGQSSGYGQHGSSSGHSSTHG 611
Query: 101 GSAGSFKPGTGYSQVSYSSGSGSSL-QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSS 159
+ + Q +SG SS Q SGSSQ SS G GS SG S S S
Sbjct: 612 QHGSTSGQSSSCGQHGATSGQSSSHGQHGSGSSQ----SSRYGQQGSGSGQSPSRGRHGS 667
Query: 160 SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQP-GQSSSSSQTFGVS--SSGQSVSS--- 213
F SSS Q G+GS +++ + + S G S S Q+ G S SG S SS
Sbjct: 668 DFGHSSSYGQHGSGSGWSSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYR 727
Query: 214 --NQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSG-APGVVQG 270
R S + S + S G + SH SG R GSG +P V+
Sbjct: 728 KHGSRSGQSSRSEQHGSSSGLSSSYGQHGSGSHQSSGHGR------QGSGSGHSPSRVRH 781
Query: 271 PPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSY----LVPGMTYSKGKIYPVGYFTK 326
S TS S G YE G + + G YS+ G+F+
Sbjct: 782 GSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQHG-SASGHFSS 840
Query: 327 ENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTG 386
+ + G S + S G+ S+ +SA+ A G+G Q G G G
Sbjct: 841 QGRHGSTSGQSSSSGQHDSSSGQ---SSSYGQHESASHHASGRGRHGSGSGQSPGHGQRG 897
Query: 387 SKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQ 446
S SPS R S S SSSSG H GS S G SSS QSSG
Sbjct: 898 SGSGQSPSYGRHGSGSGRSSSSG--RHGSGSGQSS-------GFGHKSSSGQSSGYT--- 945
Query: 447 PCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGK 493
S SGH SS G G G+ SSS G+
Sbjct: 946 ---QHGSGSGHS----SSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQ 985
Score = 94.4 bits (233), Expect = 2e-19
Identities = 137/443 (30%), Positives = 163/443 (36%), Gaps = 89/443 (20%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G SSG SS G SGSS +SSG G GS SG S G + Y + + S
Sbjct: 1093 GASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGS 1146
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
GSG S S LG SS G S SG SSS+S S SS Q G+ S
Sbjct: 1147 GSGRSSSSGQHGSGLGESSGF-GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG---- 1201
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSG--GPIVSHSG 237
S RG + G SS SS +G SG SS S SP G G + HS
Sbjct: 1202 -QSSRG----ERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHS- 1255
Query: 238 PYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYE 297
SSH QHGSG+ G S G P + +G +E
Sbjct: 1256 ----SSHG-------------QHGSGS-----GRSSSRG-----PYESRSGHSSVFGQHE 1288
Query: 298 VVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPII 357
G S +Y G G+F + G G S + EG
Sbjct: 1289 SGSGHSSAYSQHGS--------GSGHFCSQ----GQHGSTSGQSSTFDQEG--------- 1327
Query: 358 PSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGS 417
S+ + ++ G+G Q G G G+ SPS R S S SSS G H GS
Sbjct: 1328 ---SSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYG--QHGSGS 1382
Query: 418 ASQSPCSPPGTGSFSS-------SSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGG 470
S G+GS S SSS QSSG C S SGH SS G
Sbjct: 1383 GWSSSSGRHGSGSGQSSGFGHHESSSWQSSG------CTQHGSGSGHS----SSYEQHGS 1432
Query: 471 PDGSPHPDPSAGAKPCGSSSAGK 493
G G+ SSS G+
Sbjct: 1433 RSGQSSRGERHGSSSGSSSSYGQ 1455
Score = 93.2 bits (230), Expect = 5e-19
Identities = 136/449 (30%), Positives = 163/449 (36%), Gaps = 67/449 (14%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G SSG SS G SGSS +SSG G GS SG S G + Y + + S
Sbjct: 1563 GASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGS 1616
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
GSG S S LG SS G S SG SSS+S S SS Q G+ S
Sbjct: 1617 GSGRSSSSGQHGSGLGESSGF-GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG---- 1671
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSG--GPIVSHSG 237
S RG + G SS SS +G SG SS S SP G G + HS
Sbjct: 1672 -QSSRG----ERHGSSSRSSSRYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHS- 1725
Query: 238 PYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYE 297
SSH QHGSG+ G S G P + +G +E
Sbjct: 1726 ----SSHG-------------QHGSGS-----GRSSSRG-----PYESRSGHSSVFGQHE 1758
Query: 298 VVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPII 357
G S +Y G G G + + + G S G++ S +
Sbjct: 1759 SGSGHSSAYSQHGS--GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 1816
Query: 358 PSQSAASSAIAFQPV----GTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYH 413
S S P G+G G GS S SS R S S SSG +H
Sbjct: 1817 SSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS--GQSSGFGHH 1874
Query: 414 PCGSASQSPCSPPGTGSFSSSSSSQ--------SSGKIILQPCGSKSSSSGHPCMSVSSL 465
S S + G+GS SSS Q S G+ GS SS H S S
Sbjct: 1875 ESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGEQHGSSSGSSSSYGQHG--SGSRQ 1932
Query: 466 TLTGGPDGS---PHPDPSAGAKPCGSSSA 491
+L G GS P PS G GS +
Sbjct: 1933 SLGHGQHGSGSGQSPSPSRGRHGSGSGQS 1961
Score = 92.8 bits (229), Expect = 7e-19
Identities = 147/482 (30%), Positives = 180/482 (37%), Gaps = 100/482 (20%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G SG SS + + SGS SS S SSG SSG S GS S +GY Q + S
Sbjct: 209 GSGSGQSSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHS----SGYGQ--HGS 262
Query: 120 GSGSSLQGASGSSQLGSSSSH----SGS---------------------SGSHSGSSSSH 154
SG S +G S GSSSS+ SGS GS SG SSSH
Sbjct: 263 RSGQSSRGERHRSSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSH 322
Query: 155 S--SSSSSFQFSSSSFQVGNG--SALPTNDNSYRGILNPSQPGQSS--SSSQTFGVSSSG 208
S SS+ +S ++ G+G S +++ S+ G S SSSQ S+SG
Sbjct: 323 GQHGSGSSYSYSRGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSG 382
Query: 209 QSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVV 268
Q+ SS Q SS S HS HS GQ P HG G
Sbjct: 383 QASSSGQHGSSSRQSSSYGQHESASRHSSG--RGQHSSGSGQSP------GHGQRGSGSG 434
Query: 269 QGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKEN 328
Q P G G+ G SS S Y G Y G+ E+
Sbjct: 435 QSPSSGQHGT----------------GF---GRSSSS-----GPYVSGSGYSSGFGHHES 470
Query: 329 PVKGSPGVPSFAAGPPISEG------KYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGG 382
+ S G +G S G + S+ S+A S+ ++ G+G Q G
Sbjct: 471 SSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSYGQHGSGSRQSLGH 530
Query: 383 GSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSS------- 435
GS SPS SR S SS H GS S P +GS SS
Sbjct: 531 SRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSSRGPYESGSGHSSGLGHQESR 590
Query: 436 SSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSA----GAKPCGSSSA 491
S QSSG G SSSGH + T G GS S+ GA SSS
Sbjct: 591 SGQSSG------YGQHGSSSGH--------SSTHGQHGSTSGQSSSCGQHGATSGQSSSH 636
Query: 492 GK 493
G+
Sbjct: 637 GQ 638
Score = 91.7 bits (226), Expect = 2e-18
Identities = 135/447 (30%), Positives = 161/447 (36%), Gaps = 63/447 (14%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G SSG SS G SGSS +SSG G GS SG S G + Y + + S
Sbjct: 2033 GASSGQSSSHGQHGSGSS----QSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGR--HGS 2086
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
GSG S LG SS G S SG SSS+S S SS Q G+ S
Sbjct: 2087 GSGRSSSSGQHGPGLGESSGF-GHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSG---- 2141
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPY 239
S RG + G SS SS +G SG SS S SP G H
Sbjct: 2142 -QSSRG----ERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRG----RHGS-- 2190
Query: 240 IPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVV 299
S HS S G QHGSG+ G S G P + +G +E
Sbjct: 2191 -GSGHSSSHG---------QHGSGS-----GRSSSRG-----PYESRSGHSSVFGQHESG 2230
Query: 300 GGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPS 359
G S +Y G G G + + + G S G++ S + S
Sbjct: 2231 SGHSSAYSQHGS--GSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSS 2288
Query: 360 QSAASSAIAFQPV----GTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPC 415
S P G+G G GS S SS R S S SSG +H
Sbjct: 2289 YGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGS--GQSSGFGHHES 2346
Query: 416 GSASQSPCSPPGTGSFSSSSSSQ--------SSGKIILQPCGSKSSSSGHPCMSVSSLTL 467
S S + G+GS SSS Q S G+ GS SS H S S +L
Sbjct: 2347 SSWQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRGERHGSSSGSSSSYGQHG--SGSRQSL 2404
Query: 468 TGGPDGS---PHPDPSAGAKPCGSSSA 491
G GS P PS G GS +
Sbjct: 2405 GHGQHGSGSGQSPSPSRGRHGSGSGQS 2431
Score = 90.1 bits (222), Expect = 4e-18
Identities = 126/441 (28%), Positives = 166/441 (37%), Gaps = 36/441 (8%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G G S SG S S +R G SG SS S GS S G S S+
Sbjct: 1457 GSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSSH 1516
Query: 118 SSGSG---SSLQGASGSSQLGSSSSHSGSSGSH---SGSSSSHSSSSSSFQFSSSSFQVG 171
SSG G S +SG Q GSSS HS + G H SG SSS +S SSS Q G
Sbjct: 1517 SSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHG 1576
Query: 172 NGSALPTNDNSYRGILNPS----QPGQSSSSSQTFG--VSSSGQSVSSNQRPC----SSD 221
+GS+ + S Q G S S ++G S SG+S SS Q SS
Sbjct: 1577 SGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSG 1636
Query: 222 IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGK 281
S G S+S S HS G QHGS + +G +
Sbjct: 1637 FGHHESSSGQSSSYSQHGSGSGHSSGYG---------QHGSRSGQSSRGERHGSSSRSSS 1687
Query: 282 PCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAA 341
S + G+ G S G + S+G+ + + GS S +
Sbjct: 1688 RYGQHGSGSRQSSGHGRQGSGS------GQSPSRGRHGSGLGHSSSHGQHGSGSGRSSSR 1741
Query: 342 GPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS 401
GP E + S+ +S + + A+ G+G C G GS S + + SS
Sbjct: 1742 GP--YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSS 1799
Query: 402 SSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQ-SSGKIILQPCGSKSSSSGHPCM 460
+ SSS G H GS+ S G+GS S S + SG G S SG
Sbjct: 1800 TGQSSSHG--QHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSYGQHGSGSGWSSS 1857
Query: 461 SVSSLTLTGGPDGSPHPDPSA 481
S + +G G H + S+
Sbjct: 1858 SGRHGSGSGQSSGFGHHESSS 1878
Score = 89.7 bits (221), Expect = 6e-18
Identities = 142/511 (27%), Positives = 177/511 (34%), Gaps = 83/511 (16%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSG------------------ 90
+S ND +G G SSGFS + SS S S S G SSG
Sbjct: 215 SSSNDTHGSGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGYGQHGSRSGQSSRGERHR 274
Query: 91 SSSGSSIAQGG-------SAGSFKPGTGYSQ----VSYSSGSGSSL---QGASGSSQLGS 136
SSSGSS + G S G + G+G Q V + SGSG S Q SGSS S
Sbjct: 275 SSSGSSSSYGQHGSGSRQSLGHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYS 334
Query: 137 SSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSS 196
+ SG SG S S S +S G+ S+ + ++ + Q G SS
Sbjct: 335 RGHYESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSS 394
Query: 197 SSSQTFG---------------VSSSGQSVSSNQRPCSSDIPDSPCSG------------ 229
S ++G S SGQS QR S SP SG
Sbjct: 395 RQSSSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSG--QSPSSGQHGTGFGRSSSS 452
Query: 230 GPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPGKPCPPI 286
GP VS SG H S + QHGSG + G Q S G+
Sbjct: 453 GPYVSGSGYSSGFGHHESSSEHSSGYT--QHGSGSGHSSGHGQHGSRSGQSSRGERQGSS 510
Query: 287 TSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPIS 346
SYG + S + G + G + S G + +G S
Sbjct: 511 AGSSSSYGQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGSRQSSSYGPHGYGSGRSSS 570
Query: 347 EGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS 406
G Y S S SS + Q +G Q G G GS S + + S+S SS
Sbjct: 571 RGPY-------ESGSGHSSGLGHQESRSG--QSSGYGQHGSSSGHSSTHGQHGSTSGQSS 621
Query: 407 SSGLPYHPCGSASQSPCSPPGTGSFSSSS-SSQSSGKIILQPCGSKSSSSGHPCM----- 460
S G H S S G+GS SS Q SG G S GH
Sbjct: 622 SCG--QHGATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHG 679
Query: 461 SVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S S + + GP GS S GS +
Sbjct: 680 SGSGWSSSNGPHGSVSGQSSGFGHKSGSGQS 710
Score = 89.7 bits (221), Expect = 6e-18
Identities = 147/477 (30%), Positives = 180/477 (37%), Gaps = 89/477 (18%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSS--------GSSISSARSSGGGSSGSSSGSSIAQG 100
+S N P + G SSGF SGS S GSS SS G SG SS S Q
Sbjct: 685 SSSNGPHGSVSGQSSGFGHKSGSGQSSGYSQHGSGSSHSSGYRKHGSRSGQSSRSE--QH 742
Query: 101 GSAGSFKPGTGYSQVSYSSGSGSSLQGA-SGSS----QLGSSSSHSGSSGSHSGSSSSHS 155
GS+ G SG QG+ SG S + GSSS HS S G H GS +S S
Sbjct: 743 GSSSGLSSSYGQHGSGSHQSSGHGRQGSGSGHSPSRVRHGSSSGHSSSHGQH-GSGTSCS 801
Query: 156 SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSS--SSQTFGVSSSGQSVSS 213
SS ++ S S G G + Y SQ G +S SSQ S+SGQS SS
Sbjct: 802 SSCGHYE-SGSGQASGFGQHESGSGQGY------SQHGSASGHFSSQGRHGSTSGQSSSS 854
Query: 214 NQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPC 273
Q SS S G + +SH SG R HGSG+ Q P
Sbjct: 855 GQHDSSSGQSSS----------YGQHESASHHASGRGR--------HGSGSG---QSPGH 893
Query: 274 SNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGS 333
G P SYG + G S S + G G+ K + + S
Sbjct: 894 GQRGSGSGQSP-------SYGRHGSGSGRSSS----SGRHGSGSGQSSGFGHKSSSGQSS 942
Query: 334 PGVPSFAAGPPISE------GKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGS 387
G +G S + S+ S++ S+ ++ G+G Q G G GS
Sbjct: 943 -GYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGS 1001
Query: 388 KGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSS-------SSQSS 440
SPS SR S SS + GS S P +GS SS S QSS
Sbjct: 1002 GSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSS 1061
Query: 441 GKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSA----GAKPCGSSSAGK 493
G G SSSGH + T G GS S+ GA SSS G+
Sbjct: 1062 G------YGQHGSSSGH--------SSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQ 1104
Score = 89.7 bits (221), Expect = 6e-18
Identities = 148/504 (29%), Positives = 181/504 (35%), Gaps = 75/504 (14%)
Query: 50 SPNDPCLTGKGDSSGFSSYSGSSSSGSSISSA---------RSSGGGSSGSSSGSSIAQG 100
S + P G SSG SS G SG+S SS+ ++SG G S SG +Q
Sbjct: 772 SGHSPSRVRHGSSSGHSSSHGQHGSGTSCSSSCGHYESGSGQASGFGQHESGSGQGYSQH 831
Query: 101 GSAGSFKPGTG----YSQVSYSSGSGSSLQGASGSSQLGSSSSH----SGSSGSHSGSSS 152
GSA G S S SSG S G S S S+SH G GS SG S
Sbjct: 832 GSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQHESASHHASGRGRHGSGSGQSP 891
Query: 153 SHSSSSSSFQFSSSSFQVGNGSALPTNDNSY-------RGILNPSQPGQSS--------- 196
H S S S + G+GS ++ + G + S GQSS
Sbjct: 892 GHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQSSGFGHKSSSGQSSGYTQHGSGS 951
Query: 197 --SSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVV 254
SSS S SGQS S Q SS S S G S S + SG +
Sbjct: 952 GHSSSYEQHGSRSGQSSRSEQHGSSS---GSSSSYGQHGSGSRQSLGHGQHGSGSGQSPS 1008
Query: 255 VVVDQHGSGA-PGVVQGPPCSNGGLPGK--PCPPITSVDKSYGGYEVVGGSSDSYLVPGM 311
+HGSG+ GP S G P + G E G S Y G
Sbjct: 1009 PSRGRHGSGSGQSSSYGPYRSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGS 1068
Query: 312 TYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQP 371
S G G + S G ++G S G++ S +S + +
Sbjct: 1069 --SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH---------GSGSSQSSGYGR 1117
Query: 372 VGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS-----------SSGLPYHPCGSASQ 420
G+G Q G G GS SPS R S S SS SSG +H S
Sbjct: 1118 QGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQS 1177
Query: 421 SPCSPPGTGSFSSSS----SSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGG----PD 472
S S G+GS SS S+S + GS S SS H S + G
Sbjct: 1178 SSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGS 1237
Query: 473 GSPHPDPSAGAKPCG---SSSAGK 493
GS H PS G G SSS G+
Sbjct: 1238 GSGH-SPSRGRHGSGLGHSSSHGQ 1260
Score = 89.4 bits (220), Expect = 8e-18
Identities = 148/514 (28%), Positives = 185/514 (35%), Gaps = 84/514 (16%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSS-----SGSSIAQGGSA 103
TS +G S+G SS G SGSS SS+ G SG S GS S
Sbjct: 1786 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSY 1845
Query: 104 GSFKPGTGYSQVSYSSGSG-----------SSLQGASGSSQLGSSSSHSGS---SGSHSG 149
G G+G+S S GSG SS +SG +Q GS S HS S GS SG
Sbjct: 1846 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 1905
Query: 150 SSSSHSSSSSSFQFSSSSFQVGNGS--ALPTNDNSYRGILNPS----QPGQSSSSSQTFG 203
SS SS SSS Q G+GS +L + +PS + G S S ++G
Sbjct: 1906 QSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYG 1965
Query: 204 VSSSGQSVSSNQRPC-------------------SSDIPDSPCSGGPIVSHSGPYIPSSH 244
SG SS++ P SS S G +H S
Sbjct: 1966 PYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSASGQ 2025
Query: 245 SVSGGQRPVVVVVD----QHGSGA----------PGVVQGPPCSNGGLPGKPCPPITSVD 290
S S GQ QHGSG+ G Q P G + P
Sbjct: 2026 SSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSP------ 2079
Query: 291 KSYGGYEVVGG--SSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEG 348
SYG + G SS PG+ S G G+ + S +G G
Sbjct: 2080 -SYGRHGSGSGRSSSSGQHGPGLGESSG----FGHHESSSGQSSSYSQHGSGSGHSSGYG 2134
Query: 349 KYFS----SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSI 404
++ S S+ S++ S+ + G+G Q G G GS SPS R S S
Sbjct: 2135 QHGSRSGQSSRGERHGSSSGSSSRYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGSGH 2194
Query: 405 SSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQ-SSGKIILQPCGSKSSSSGHPCM--- 460
SSS G H GS S P + S SS Q SG S SGH C
Sbjct: 2195 SSSHG--QHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQ 2252
Query: 461 --SVSSLTLTGGPDGSPHPDPSA-GAKPCGSSSA 491
S S + T +GS S+ G GSS +
Sbjct: 2253 HGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQS 2286
Score = 87.0 bits (214), Expect = 4e-17
Identities = 127/450 (28%), Positives = 155/450 (34%), Gaps = 70/450 (15%)
Query: 67 SYSGSSSS----GSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSG 122
S SG SS+ GSS + S G SGSS SS Q GS P G + SGSG
Sbjct: 1785 STSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRG----RHGSGSG 1840
Query: 123 SSL---QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
S Q SGS SS H SG SG SSS S ++ G+ S+ +
Sbjct: 1841 HSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQH 1900
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSG--QSVSSNQRPCSSDIPDSPCSGGPIVSHSG 237
+ Q G SS SS ++G SG QS+ Q S SP G
Sbjct: 1901 GSRSGQSSRGEQHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRG-------- 1952
Query: 238 PYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYE 297
H GQ +GSG+ P +G + G E
Sbjct: 1953 -----RHGSGSGQSS---SYGPYGSGSGWSSSRGPYESG----------SGHSSGLGHRE 1994
Query: 298 VVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPII 357
G S Y G S G G + S G ++G S G++
Sbjct: 1995 SRSGQSSGYGQHGS--SSGHSSTHGQHGSASGQSSSCGQHGASSGQSSSHGQH------- 2045
Query: 358 PSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS----------- 406
S +S + + G+G Q G G GS SPS R S S SS
Sbjct: 2046 --GSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGPGLGE 2103
Query: 407 SSGLPYHPCGSASQSPCSPPGTGSFSSS--------SSSQSSGKIILQPCGSKSSSSGHP 458
SSG +H S S S G+GS SS S S G+ GS S H
Sbjct: 2104 SSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSRYGQHG 2163
Query: 459 CMSVSSLTLTGGPDGSPHPDPSAGAKPCGS 488
S S GS H PS G GS
Sbjct: 2164 SGSRQSSGHGRQGSGSGH-SPSRGRHGSGS 2192
Score = 87.0 bits (214), Expect = 4e-17
Identities = 130/443 (29%), Positives = 165/443 (37%), Gaps = 57/443 (12%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSS-----SGSSIAQGGSA 103
TS +G S+G SS G SGSS SS+ G SG S GS S
Sbjct: 2256 TSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQSPSRGRHGSGSGHSSSY 2315
Query: 104 GSFKPGTGYSQVSYSSGSG-----------SSLQGASGSSQLGSSSSHSGS---SGSHSG 149
G G+G+S S GSG SS +SG +Q GS S HS S GS SG
Sbjct: 2316 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSG 2375
Query: 150 SSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQ 209
SS SS SSS Q G+GS + S GQS S S+ G SG
Sbjct: 2376 QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH-----GSGSGQSPSPSR--GRHGSGS 2428
Query: 210 SVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQ 269
SS+ P SG S GPY S SG G G G
Sbjct: 2429 GQSSSYSPYG--------SGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSS 2480
Query: 270 GPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIY-PVGYFTKEN 328
G ++G + S G + G S S+ G S+ Y G + ++
Sbjct: 2481 GHSSTHG-----QHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQS 2535
Query: 329 PVKGSPG-----VPSF-----AAGPPISEGKYFS----SNPIIPSQSAASSAIAFQPVGT 374
P G G PS+ +G S G++ S S+ +S++ + ++ G+
Sbjct: 2536 PGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGS 2595
Query: 375 GGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSS 434
G G G GS+ S R SSS SS G H GS S G+GS S
Sbjct: 2596 GSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSHYG--QHGSGSRQSSGHGRQGSGSGQSP 2653
Query: 435 SSSQ-SSGKIILQPCGSKSSSSG 456
S + SG G S SG
Sbjct: 2654 SRGRHGSGLGHSSSHGQHGSGSG 2676
Score = 85.9 bits (211), Expect = 8e-17
Identities = 131/444 (29%), Positives = 165/444 (37%), Gaps = 59/444 (13%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSS-----SGSSIAQGGSA 103
TS +G S+G SS G SGSS SS G SG S GS S
Sbjct: 1316 TSGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSY 1375
Query: 104 GSFKPGTGYSQVSYSSGSG-----------SSLQGASGSSQLGSSSSHSGS---SGSHSG 149
G G+G+S S GSG SS +SG +Q GS S HS S GS SG
Sbjct: 1376 GQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSG 1435
Query: 150 SSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQ 209
SS SS SSS Q G+GS + S GQS S S+ G SG
Sbjct: 1436 QSSRGERHGSSSGSSSSYGQHGSGSRQSLGHGQH-----GSGSGQSPSPSR--GRHGSGS 1488
Query: 210 SVSSNQRPCSSDIPDSPCSGGPIVSHSGPY-IPSSHSVSGGQRPVVVVVDQHGSGAPGVV 268
SS+ P SG S GPY SSHS G R + + G
Sbjct: 1489 GQSSSYSPYG--------SGSGWSSSRGPYESGSSHSSGLGHR------ESRSGQSSGYG 1534
Query: 269 QGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIY-PVGYFTKE 327
Q S + S G + G S S+ G S+ Y G + +
Sbjct: 1535 QHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQ 1594
Query: 328 NPVKGSPG-----VPSF-----AAGPPISEGKYFS----SNPIIPSQSAASSAIAFQPVG 373
+P G G PS+ +G S G++ S S+ +S++ + ++ G
Sbjct: 1595 SPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHG 1654
Query: 374 TGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSS 433
+G G G GS+ S R SSS SS G H GS S G+GS S
Sbjct: 1655 SGSGHSSGYGQHGSRSGQSSRGERHGSSSRSSSRYG--QHGSGSRQSSGHGRQGSGSGQS 1712
Query: 434 SSSSQ-SSGKIILQPCGSKSSSSG 456
S + SG G S SG
Sbjct: 1713 PSRGRHGSGLGHSSSHGQHGSGSG 1736
Score = 84.7 bits (208), Expect = 2e-16
Identities = 137/467 (29%), Positives = 158/467 (33%), Gaps = 92/467 (19%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS-----GSSIAQGGSAGSFKPGTGYSQ 114
G +SG SS G SGSS SS G SG S GS S G G+G+S
Sbjct: 627 GATSGQSSSHGQHGSGSSQSSRYGQQGSGSGQSPSRGRHGSDFGHSSSYGQHGSGSGWSS 686
Query: 115 VS--------------YSSGSGSSLQGASGSSQLGSSSSHSG---SSGSHSGSSSSHSSS 157
+ + SGSG S SG SQ GS SSHS GS SG SS
Sbjct: 687 SNGPHGSVSGQSSGFGHKSGSGQS----SGYSQHGSGSSHSSGYRKHGSRSGQSSRSEQH 742
Query: 158 SSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
SS SSS Q G+GS + +S G G S S+ SSSG S S Q
Sbjct: 743 GSSSGLSSSYGQHGSGS----HQSSGHG---RQGSGSGHSPSRVRHGSSSGHSSSHGQHG 795
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGG 277
SG S G Y S SG QH SG
Sbjct: 796 ----------SGTSCSSSCGHYESGSGQASG--------FGQHESG-------------- 823
Query: 278 LPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYS-KGKIYPVGYFTKENPVKGSPGV 336
S GY G +S + G S G+ G + S G
Sbjct: 824 --------------SGQGYSQHGSASGHFSSQGRHGSTSGQSSSSGQHDSSSGQSSSYGQ 869
Query: 337 PSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQP-VGTGGVQLCGGGSTGSKGPCSPSS 395
A+ G++ S + P S P G G S+G G S S
Sbjct: 870 HESASHHASGRGRHGSGSGQSPGHGQRGSGSGQSPSYGRHGSGSGRSSSSGRHGSGSGQS 929
Query: 396 SRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSS 455
S SS SSG H GS S G+ S SS S Q GS SS
Sbjct: 930 SGFGHKSSSGQSSGYTQHGSGSGHSSSYEQHGSRSGQSSRSEQHGSS-----SGSSSSYG 984
Query: 456 GHPCMSVSSLTLTGGPDGS---PHPDPSAGAKPCGSSSAGKI-PCRS 498
H S S +L G GS P PS G GS + P RS
Sbjct: 985 QHG--SGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRS 1029
Score = 84.3 bits (207), Expect = 2e-16
Identities = 133/464 (28%), Positives = 169/464 (36%), Gaps = 70/464 (15%)
Query: 50 SPNDPCLTGKGDSSGFSSYSGSSSSGSSISSAR----------------SSGGGSS---- 89
S + P G SG SS G SGS SS+R SG G S
Sbjct: 2179 SGHSPSRGRHGSGSGHSSSHGQHGSGSGRSSSRGPYESRSGHSSVFGQHESGSGHSSAYS 2238
Query: 90 --GSSSGSSIAQG------GSAGSFK---PGTGYSQVSYSSGSGSSLQGASGSSQLGSSS 138
GS SG +QG G + +F TG S GSGSS + G GS
Sbjct: 2239 QHGSGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSHGQHGSGSSQSSSYGQQGSGSGQ 2298
Query: 139 SHS-GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPT----NDNSYRGILNPSQPG 193
S S G GS SG SSS+ S +SSSS + G+GS + +++S +Q G
Sbjct: 2299 SPSRGRHGSGSGHSSSYGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSSWQSSGYTQHG 2358
Query: 194 QSSSSSQTFGV--SSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQR 251
S S ++ S SGQS + SS S S G S S + SG +
Sbjct: 2359 SGSGHSSSYEQHGSRSGQSSRGERHGSSS---GSSSSYGQHGSGSRQSLGHGQHGSGSGQ 2415
Query: 252 PVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITS---VDKSYGGYEVVGGSSDSYLV 308
+HGSG+ P +G P S G E G S Y
Sbjct: 2416 SPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPYESGSGHSSGLGHRESRSGQSSGYGQ 2475
Query: 309 PGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIA 368
G S G G + S G ++G S G++ S +S +
Sbjct: 2476 HGS--SSGHSSTHGQHGSTSGQSSSCGQHGASSGQSSSHGQH---------GSGSSQSSG 2524
Query: 369 FQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS-----------SSGLPYHPCGS 417
+ G+G Q G G GS SPS R S S SS SSG +H S
Sbjct: 2525 YGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSSSGQHGSGLGESSGFGHHESSS 2584
Query: 418 ASQSPCSPPGTGSFSSSS----SSQSSGKIILQPCGSKSSSSGH 457
S S G+GS SS S+S + GS S SS H
Sbjct: 2585 GQSSSYSQHGSGSGHSSGYGQHGSRSGQSSRGERHGSSSGSSSH 2628
Score = 84.3 bits (207), Expect = 2e-16
Identities = 133/464 (28%), Positives = 167/464 (35%), Gaps = 70/464 (15%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS-------GSSIAQGGSAGSFKPGTGY 112
G SSG SS G SGS S G SG S GS Q S + G+G+
Sbjct: 2384 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGW 2443
Query: 113 SQVS--YSSGSGSSLQ---------GASGSSQLGSSSSHSGSSGSH---SGSSSSHSSSS 158
S Y SGSG S +SG Q GSSS HS + G H SG SSS
Sbjct: 2444 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 2503
Query: 159 SSFQFSSSSFQVGNGSALPTNDNSYRGILNPS----QPGQSSSSSQTFGV--SSSGQSVS 212
+S SSS Q G+GS+ + S Q G S S ++G S SG+S S
Sbjct: 2504 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 2563
Query: 213 SNQRPC----SSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVV 268
S Q SS S G S+S S HS GQ HGS
Sbjct: 2564 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQ---------HGS------ 2608
Query: 269 QGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKEN 328
+ S G G + + G G G + S+G+ + +
Sbjct: 2609 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSH 2668
Query: 329 PVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSK 388
GS S + GP E + S+ +S + + A+ G+G C G GS
Sbjct: 2669 GQHGSGSGRSSSRGP--YESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 2726
Query: 389 GPCSPSSSRVPSSSSISSS-----------SGLPYHPCGSASQSPCSPPGTGSFSSSS-- 435
S + + SS+ SSS SG H GS G+GS SSS
Sbjct: 2727 SGQSSTFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSYG 2786
Query: 436 -----SSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGS 474
S QSSG GS S G+ S GG GS
Sbjct: 2787 QHGSGSGQSSG---YSQHGSGSGQDGYSYCKGGS-NHDGGSSGS 2826
Score = 84.0 bits (206), Expect = 3e-16
Identities = 131/428 (30%), Positives = 161/428 (37%), Gaps = 39/428 (9%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSS-----GSSSGSSIAQGGSAGSFKPGTG 111
+G G SSGF + SS S + S G SS GS SG S ++G GS G+
Sbjct: 2333 SGSGQSSGFGHHESSSWQSSGYTQHGSGSGHSSSYEQHGSRSGQS-SRGERHGS-SSGSS 2390
Query: 112 YSQVSYSSGSGSSL-QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSS--F 168
S + SGS SL G GS S S G GS SG SSS+S S +SSS +
Sbjct: 2391 SSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSGSGWSSSRGPY 2450
Query: 169 QVGNG--SALPTNDNSYRGILNPSQPGQSSSSSQTFGV--SSSGQSVSSNQRPCSSDIPD 224
+ G+G S L ++ Q G SS S T G S+SGQS S Q SS
Sbjct: 2451 ESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHGASSGQSS 2510
Query: 225 SPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPC----SNGGLPG 280
S G S S Y GQ P HG G Q P S G
Sbjct: 2511 SHGQHGSGSSQSSGY--GRQGSGSGQSP------GHGQRGSGSRQSPSYGRHGSGSGRSS 2562
Query: 281 KPCPPITSVDKS--YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPS 338
+ + +S +G +E G S SY G Y G +
Sbjct: 2563 SSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGY--GQHGSRSGQSSRGERHG 2620
Query: 339 FAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPV-GTGGVQLCGGGSTGSKGPCSP-SSS 396
++G G++ S + S P G G L S G G S SSS
Sbjct: 2621 SSSGSSSHYGQHGSGSRQSSGHGRQGSGSGQSPSRGRHGSGLGHSSSHGQHGSGSGRSSS 2680
Query: 397 RVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGS--FSS-----SSSSQSSGKIILQPCG 449
R P S + SS H GS S S G+GS F S S+S QSS
Sbjct: 2681 RGPYESRLGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGSTSGQSSTFDQEGSST 2740
Query: 450 SKSSSSGH 457
+SSS GH
Sbjct: 2741 GQSSSYGH 2748
Score = 82.4 bits (202), Expect = 9e-16
Identities = 128/454 (28%), Positives = 168/454 (37%), Gaps = 51/454 (11%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS-------GSSIAQGGSAGSFKPGTGY 112
G SSG SS G SGS S G SG S GS Q S G ++ G+G+
Sbjct: 974 GSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYGPYRSGSGW 1033
Query: 113 SQVS--YSSGSGSSL-----QGASG-SSQLGSSSSHSGSSGSH------SGSSSSHSSSS 158
S Y SGSG S + SG SS G S SG S +H SG SSS
Sbjct: 1034 SSSRGPYESGSGHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSSCGQHG 1093
Query: 159 SSFQFSSSSFQVGNGSALPTNDNSYRGILNPS----QPGQSSSSSQTFG--VSSSGQSVS 212
+S SSS Q G+GS+ + S Q G S S ++G S SG+S S
Sbjct: 1094 ASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGSGRSSS 1153
Query: 213 SNQRPC----SSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVV 268
S Q SS S G S+S S HS G QHGS
Sbjct: 1154 SGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYG---------QHGS------ 1198
Query: 269 QGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKEN 328
+ S G G + + G G G + S+G+ + +
Sbjct: 1199 RSGQSSRGERHGSSSGSSSHYGQHGSGSRQSSGHGRQGSGSGHSPSRGRHGSGLGHSSSH 1258
Query: 329 PVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSK 388
GS S + GP E + S+ +S + + A+ G+G C G GS
Sbjct: 1259 GQHGSGSGRSSSRGP--YESRSGHSSVFGQHESGSGHSSAYSQHGSGSGHFCSQGQHGST 1316
Query: 389 GPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQ-SSGKIILQP 447
S + + SS+ SSS G + GS+ S G GS S S + SG
Sbjct: 1317 SGQSSTFDQEGSSTGQSSSYG--HRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSS 1374
Query: 448 CGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSA 481
G S SG S + +G G H + S+
Sbjct: 1375 YGQHGSGSGWSSSSGRHGSGSGQSSGFGHHESSS 1408
Score = 81.3 bits (199), Expect = 2e-15
Identities = 146/526 (27%), Positives = 185/526 (35%), Gaps = 108/526 (20%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQG------------------- 100
G SSG SS+ G SGS +SSG G GS SG S ++G
Sbjct: 1210 GSSSGSSSHYGQHGSGSR----QSSGHGRQGSGSGHSPSRGRHGSGLGHSSSHGQHGSGS 1265
Query: 101 ---GSAGSFKPGTGYSQV--SYSSGSGSSLQGASGSSQLGSSSSH---SGSSGSHSGSSS 152
S G ++ +G+S V + SGSG S S SQ GS S H G GS SG SS
Sbjct: 1266 GRSSSRGPYESRSGHSSVFGQHESGSGHS----SAYSQHGSGSGHFCSQGQHGSTSGQSS 1321
Query: 153 SHSSSSSSFQFSSSSFQVGNGSA--------------LPTNDNSYRGILNPSQPGQS--- 195
+ SS SSS G+GS+ P+ G + S GQ
Sbjct: 1322 TFDQEGSSTGQSSSYGHRGSGSSQSSGYGRHGAGSGQSPSRGRHGSGSGHSSSYGQHGSG 1381
Query: 196 ---SSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPY------------- 239
SSSS G S SGQS SS G HS Y
Sbjct: 1382 SGWSSSSGRHG-SGSGQSSGFGHHESSSWQSSGCTQHGSGSGHSSSYEQHGSRSGQSSRG 1440
Query: 240 --------IPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPG--KPCPPI 286
SS+ G + QHGSG +P +G S G P
Sbjct: 1441 ERHGSSSGSSSSYGQHGSGSRQSLGHGQHGSGSGQSPSPSRGRHGSGSGQSSSYSPYGSG 1500
Query: 287 TSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPIS 346
+ S G YE GSS S + G+ G + + G +G S
Sbjct: 1501 SGWSSSRGPYE--SGSSHSSGLGHRESRSGQSSGYGQHGSSSGHSSTHGQHGSTSGQSSS 1558
Query: 347 EGKYFSSNPIIPSQ----SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSS 402
G++ +S+ S S +S + + G+G Q G G GS SPS R S S
Sbjct: 1559 CGQHGASSGQSSSHGQHGSGSSQSSGYGRQGSGSGQSPGHGQRGSGSRQSPSYGRHGSGS 1618
Query: 403 SISS-----------SSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSK 451
SS SSG +H S S S G+GS SS Q + S
Sbjct: 1619 GRSSSSGQHGSGLGESSGFGHHESSSGQSSSYSQHGSGSGHSSGYGQHGSR-------SG 1671
Query: 452 SSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCR 497
SS G S S + G GS S + S +G+ P R
Sbjct: 1672 QSSRGERHGSSSRSSSRYGQHGSGSRQSSGHGRQ--GSGSGQSPSR 1715
Score = 65.9 bits (159), Expect = 9e-11
Identities = 123/455 (27%), Positives = 152/455 (33%), Gaps = 76/455 (16%)
Query: 83 SSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSG 142
SS SS S+ + GS KPGT S S +L SG
Sbjct: 125 SSFSHSSWSAGENDSYSRNVRGSLKPGT-----------------ESISRRLSFQRDFSG 167
Query: 143 SSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF 202
S+SG SSS+ +S SS Q G+GS N + S GQ SSS+ T
Sbjct: 168 QHNSYSGQSSSYGEQNSDSHQSSGRGQCGSGSGQSPNYGQH-----GSGSGQ-SSSNDTH 221
Query: 203 GVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRP---------- 252
G S SGQS +Q SS G HS Y H GQ
Sbjct: 222 G-SGSGQSSGFSQHKSSSGQSSGYSQHGSGSGHSSGY--GQHGSRSGQSSRGERHRSSSG 278
Query: 253 VVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMT 312
QHGSG+ + G G P + GS SY
Sbjct: 279 SSSSYGQHGSGSRQSL-GHGRQGSGSRQSPSHVRHGSGSGHSSSHGQHGSGSSYSYSRGH 337
Query: 313 YSKGKIYPVGY------------FTKENPVKG---SPGVPSFAAGPPISEGKYFSSNPII 357
Y G G+ ++K G S G +G S G++ SS+
Sbjct: 338 YESGSGQTSGFGQHESGSGQSSGYSKHGSGSGHSSSQGQHGSTSGQASSSGQHGSSSRQS 397
Query: 358 PS----QSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSP-----------SSSRVPSSS 402
S +SA+ + +G Q G G GS SP SSS P S
Sbjct: 398 SSYGQHESASRHSSGRGQHSSGSGQSPGHGQRGSGSGQSPSSGQHGTGFGRSSSSGPYVS 457
Query: 403 SISSSSGLPYHPCGSASQSPCSPPGTGSFSSS--------SSSQSSGKIILQPCGSKSSS 454
SSG +H S S + G+GS SS S S G+ GS SS
Sbjct: 458 GSGYSSGFGHHESSSEHSSGYTQHGSGSGHSSGHGQHGSRSGQSSRGERQGSSAGSSSSY 517
Query: 455 SGHPCMSVSSLTLTGGPDGS-PHPDPSAGAKPCGS 488
H S SL + GS P PS G GS
Sbjct: 518 GQHGSGSRQSLGHSRHGSGSGQSPSPSRGRHESGS 552
Score = 56.2 bits (134), Expect = 7e-08
Identities = 46/120 (38%), Positives = 56/120 (46%), Gaps = 11/120 (9%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
TS +G S+G SS G SGSS +SSG G G+ SG S++ G
Sbjct: 2726 TSGQSSTFDQEGSSTGQSSSYGHRGSGSS----QSSGYGRHGAGSGQSLSHGRHGSGSGQ 2781
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF-QFSSSS 167
+ Y Q + SGSG S SG SQ GS S G S GS+ SS S F F SS+
Sbjct: 2782 SSSYGQ--HGSGSGQS----SGYSQHGSGSGQDGYSYCKGGSNHDGGSSGSYFLSFPSST 2835
Score = 50.8 bits (120), Expect = 3e-06
Identities = 47/136 (34%), Positives = 61/136 (44%), Gaps = 16/136 (11%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS-----GSSIAQGGSAGSFKPGTG 111
+G G SS +S + SGS ++ G +SG SS GSS Q S G G+G
Sbjct: 2699 SGSGHSSAYSQHG----SGSGHFCSQGQHGSTSGQSSTFDQEGSSTGQSSSYG--HRGSG 2752
Query: 112 YSQVS----YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSS 167
SQ S + +GSG SL S G SSS+ G GS SG SS +S S S
Sbjct: 2753 SSQSSGYGRHGAGSGQSLSHGRHGSGSGQSSSY-GQHGSGSGQSSGYSQHGSGSGQDGYS 2811
Query: 168 FQVGNGSALPTNDNSY 183
+ G + + SY
Sbjct: 2812 YCKGGSNHDGGSSGSY 2827
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 85.5 bits (210), Expect = 1e-16
Identities = 115/445 (25%), Positives = 155/445 (34%), Gaps = 16/445 (3%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
++ +D + DSS S+ S SS S S +S+ SS S +SS SS + S S
Sbjct: 721 SNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 780
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
+ S S +S S +S SS SS S SS S S +SS S+SS S S+SS
Sbjct: 781 NSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSD 840
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCS 228
+ + +D+ + S SS SS + S S S SN+ SSD DS S
Sbjct: 841 SSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Query: 229 GGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITS 288
S S SS S + S + SN S
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSD-------SSESSNSSDNSNSSDSSNSSDSSDSSDSSNS 953
Query: 289 VDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEG 348
D S SSDS S + ++ S ++ S
Sbjct: 954 SDSSNSSDS--SNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSD 1011
Query: 349 KYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSS 408
SSN S S+ SS + + + S SS SS S SS
Sbjct: 1012 SSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSD 1071
Query: 409 GLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLT 468
+S+S S + S SS SS SS S SS S S S +
Sbjct: 1072 SSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSD-------SSDSSDSSDSSDSSDSSNSS 1124
Query: 469 GGPDGSPHPDPSAGAKPCGSSSAGK 493
D S D S + SS + +
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSE 1149
Score = 82.4 bits (202), Expect = 9e-16
Identities = 120/440 (27%), Positives = 150/440 (34%), Gaps = 11/440 (2%)
Query: 52 NDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTG 111
ND +GKG S SS S SS S +S S+ SS SS S+S S S S +
Sbjct: 537 NDKSDSGKGKSD--SSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSD 594
Query: 112 YSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
S S SS S S + S SS S S SS S S SS S S S SS SS S
Sbjct: 595 SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNS 654
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGP 231
+ S + NS S SS SS + S S S S+ SS+ +S S
Sbjct: 655 DSSDSSNSSNS-------SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDS 707
Query: 232 IVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDK 291
S S SS+S S S + SN S D
Sbjct: 708 SDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDS 767
Query: 292 SYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYF 351
S SSDS S + S S + S
Sbjct: 768 SDSSDS--SDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSD 825
Query: 352 SSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLP 411
SSN S S+ SS + + G + S S S S+SS SS S
Sbjct: 826 SSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDS 885
Query: 412 YHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGP 471
S+ S S S SS+S S S+SS+S S S +
Sbjct: 886 NESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSS 945
Query: 472 DGSPHPDPSAGAKPCGSSSA 491
D S + S + SS++
Sbjct: 946 DSSDSSNSSDSSNSSDSSNS 965
Score = 78.2 bits (191), Expect = 2e-14
Identities = 119/454 (26%), Positives = 157/454 (34%), Gaps = 26/454 (5%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGS-SISSARSSGGGSSGSSSGSSI 97
S D + + +D + DSS S S S+SS S S +S+ SS +S SS SS
Sbjct: 689 SSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSD 748
Query: 98 AQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSS 157
+ S S + S S S S +S SS SS+ S SS S + S SS+SS
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSD 808
Query: 158 SSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
SS SS S + + ++D+S N S SS SS SS +S SSN
Sbjct: 809 SSDSSDSSDSDSSNSSDSSNSSDSSDSS--NSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGG 277
S S S S S SS S D S + SN
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSS-----DSDSSDSSNSSDSSDSSNSS 921
Query: 278 LPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVP 337
+ S D S SSDS + S + S
Sbjct: 922 DSSESS---NSSDNS--------NSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSD 970
Query: 338 SFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSR 397
S ++ S SS+ S S+ SS + + ++ S SS+
Sbjct: 971 SNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNS 1030
Query: 398 VPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGH 457
SS S SS +S S S + S SS SS SS S SS S
Sbjct: 1031 SDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSD-------SSDSSDSSE 1083
Query: 458 PCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S S + D S D S + SS +
Sbjct: 1084 SSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDS 1117
Score = 77.8 bits (190), Expect = 2e-14
Identities = 119/453 (26%), Positives = 161/453 (35%), Gaps = 32/453 (7%)
Query: 44 DPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSA 103
D + S +D + DSS S S SS+S +S S+ SS S SSS SS + S
Sbjct: 632 DSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSD 691
Query: 104 GSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSS----SSS 159
S + S S S S + S+ S S S SS S S+SS SS SS+
Sbjct: 692 SSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSN 751
Query: 160 SFQFSSSSFQVGNGSALPTNDNS-YRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPC 218
S S SS + + ++D+S N S SS+SS + S+S S +S+
Sbjct: 752 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSD 811
Query: 219 SSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGL 278
SSD DS S S+S SS+S D SN
Sbjct: 812 SSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS-----DSSDGSDSDSSNRSDSSNSSD 866
Query: 279 PGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPS 338
S D S SSDS + S + ++ S
Sbjct: 867 SSDSSDSSNSSDSS--------DSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSS 918
Query: 339 FAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRV 398
++ S +SN S S+ SS + S S S SS
Sbjct: 919 NSSDSSESSNSSDNSNSSDSSNSSDSS-------DSSDSSNSSDSSNSSDSSNSSDSSDS 971
Query: 399 PSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHP 458
SS S SS+ +S S S + S SS SS SS S SS S +
Sbjct: 972 NSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD-------SSNSSDSSNS 1024
Query: 459 CMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S +S + D S D S + SS++
Sbjct: 1025 SDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNS 1057
Score = 75.9 bits (185), Expect = 9e-14
Identities = 116/458 (25%), Positives = 155/458 (33%), Gaps = 16/458 (3%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSS-SSGSSISSARSSGGGSSGSSSGSSI 97
S D + +S +D + DSS S S SS SS SS SS S S S+S SS
Sbjct: 668 SSDSSDSSDSSSSSDS--SNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSD 725
Query: 98 AQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSS 157
+ ++ + S S SS S +S + S SS S S S S SS+ S S
Sbjct: 726 SDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDS 785
Query: 158 SSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
+ S S SS + + ++D+S + S SS SS + S S S S+
Sbjct: 786 NDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGG 277
SSD DS S S+S SS S + D S S+
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSS-----DSSDSNESSNSSDSSDSSNS 900
Query: 278 LPGKPCPPITSVDKS----YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGS 333
S D S SSD+ + S + S
Sbjct: 901 SDSDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSS 960
Query: 334 PGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSP 393
S + S SSN S S+ SS + + + S
Sbjct: 961 DSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSD 1020
Query: 394 SSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSS 453
SS+ SS+S SS +S S S + S SS SS SS S SS
Sbjct: 1021 SSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSD----SSDSSDSS 1076
Query: 454 SSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S S S + D S D S + SS +
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDS 1114
Score = 75.1 bits (183), Expect = 1e-13
Identities = 119/463 (25%), Positives = 157/463 (33%), Gaps = 27/463 (5%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSS------ 92
SD + +S +D + DSS S S+SS SS SS S SS SS
Sbjct: 567 SDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDS 626
Query: 93 ----SGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS 148
S SS + S S + S S SS S +S +S SS SS S SS S +
Sbjct: 627 SKSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNS-SNSSDSSDSSDSSDSSSSSDSSN 685
Query: 149 GSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSG 208
S SS SS SS+ SS S + + ++D+S + S SS + SS
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSD 745
Query: 209 QSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVV 268
S SSN S S S S S SS+S + S +
Sbjct: 746 SSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSND-------SSNSSDSSDSS 798
Query: 269 QGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKEN 328
SN S D S SSDS + S +
Sbjct: 799 NSSDSSNSS---------DSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSD 849
Query: 329 PVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSK 388
S ++ S SSN S S+ S+ + + S+ S
Sbjct: 850 GSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSS 909
Query: 389 GPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPC 448
S S S SS SS+S + S++ S S S SS SS+ S
Sbjct: 910 NSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSS 969
Query: 449 GSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S SS S S S + D S D S + SS +
Sbjct: 970 DSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1012
Score = 67.4 bits (163), Expect = 3e-11
Identities = 65/189 (34%), Positives = 80/189 (42%), Gaps = 4/189 (2%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
DSS S S SS S +S S+ SS S SS SS + S S + S S S
Sbjct: 1077 DSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1136
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS--SSSSSFQFSSSSFQVGNGSALPT 178
S+ +S SS+ SS S SS S S SS S SS SS SS + S+ +
Sbjct: 1137 DSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSS 1196
Query: 179 NDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGP 238
+ + + S SS SS + S S S SN+ SSD DS S S S
Sbjct: 1197 DSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNS--SDSSD 1254
Query: 239 YIPSSHSVS 247
SS S S
Sbjct: 1255 SSDSSDSTS 1263
Score = 65.9 bits (159), Expect = 9e-11
Identities = 106/456 (23%), Positives = 151/456 (33%), Gaps = 26/456 (5%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIA 98
SD S +D + +GD+S S S + +GS A S+ ++ S
Sbjct: 468 SDESNGNDDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSN 527
Query: 99 QGGSAG---SFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS 155
G+ G + K +G + S S +S SS S S +S S S SS S S
Sbjct: 528 GNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS 587
Query: 156 SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ 215
S SS S SS + + ++D+S + S+ S S S + S S SN
Sbjct: 588 SDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNS 647
Query: 216 RPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSN 275
S + S S S S SS S S S + SN
Sbjct: 648 SDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD----------SSNSSDSSDSSDSSN 697
Query: 276 GGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPG 335
S D S SSDS + S + ++
Sbjct: 698 SS---------ESSDSSDSSDSDSSDSSDS----SNSNSSDSDSSNSSDSSDSSNSSDSS 744
Query: 336 VPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSS 395
S ++ S SSN S S+ SS + + + S SS
Sbjct: 745 DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSS 804
Query: 396 SRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSS 455
+ SS S SS + S++ S S S SS SS S G S SS+S
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 456 GHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
S S + D S + S + SS++
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNS 900
Score = 63.5 bits (153), Expect = 4e-10
Identities = 104/424 (24%), Positives = 142/424 (33%), Gaps = 17/424 (4%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSL 125
S +G+ ++G+ + SG G S SS S S+ S S S SS S SS
Sbjct: 524 SDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSD-----SSDSDSSDSNSSS 578
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRG 185
S S S SS S SS S + S SS SS SS SS S + S+ +D+S
Sbjct: 579 DSDSSDSD-SSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSD 637
Query: 186 ILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHS 245
+ S SS SS S S S +S+ SSD DS S S+S SS S
Sbjct: 638 SKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDS--SNSSDSSDSSDS 695
Query: 246 VSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDS 305
+ + D S SN S D S SSDS
Sbjct: 696 SNSSESS-----DSSDSSDSDSSDSSDSSNSN--SSDSDSSNSSDSSDSSNS--SDSSDS 746
Query: 306 YLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASS 365
+ S + S S + S+ S +++S
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNS 806
Query: 366 AIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSP 425
+ + + + + S SS+ SS S SS G + S S
Sbjct: 807 SDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSD 866
Query: 426 PGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKP 485
S SS+SS S + S SS S + D S + S ++
Sbjct: 867 SSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSES 926
Query: 486 CGSS 489
SS
Sbjct: 927 SNSS 930
Score = 54.3 bits (129), Expect = 3e-07
Identities = 108/437 (24%), Positives = 149/437 (34%), Gaps = 45/437 (10%)
Query: 61 DSSGFSSYS--GSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
+S G+ SY S G +S+ S G +S + + S+ S S
Sbjct: 446 NSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDASYN-----SDESKD 500
Query: 119 SGSGSSLQGA------SGSSQLGSSSSHSGSSG------SHSGSSSSHSSSSSSFQFSSS 166
+G+GS +GA S S S S+ +G++G S SG S SS S S S+S
Sbjct: 501 NGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNS 560
Query: 167 SFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSP 226
S + + ++ NS + S SS SS + SS S SS+ SSD DS
Sbjct: 561 SDSSDSSDSDSSDSNSSSD--SDSSDSDSSDSSDSDSSDSSNSSDSSDSSD-SSDSSDSS 617
Query: 227 CSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPI 286
S S SS S S D + S + SN
Sbjct: 618 DSSDSKSDSSKSESDSSDSDSKSDSS-----DSNSSDSSDNSDSSDSSNSSNSSDSSDSS 672
Query: 287 TSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPIS 346
S D S SSDS + S + S ++ S
Sbjct: 673 DSSDSS--------SSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSS 724
Query: 347 EGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS 406
+ SSN S S+ SS + + + + S SS SS S +S
Sbjct: 725 DSD--SSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS 782
Query: 407 SSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLT 466
S +S S S + S SS SS SS S SS+S S S
Sbjct: 783 SDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSS--------DSDSSNSSDSSNSSDSSD 834
Query: 467 LTGGPDGSPHPDPSAGA 483
+ D S D S G+
Sbjct: 835 SSNSSDSSDSSDSSDGS 851
Score = 43.5 bits (101), Expect = 5e-04
Identities = 106/474 (22%), Positives = 153/474 (32%), Gaps = 45/474 (9%)
Query: 47 RITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSG--------------GGSSGSS 92
RIT ++ GK G G SS +I+ G G + +
Sbjct: 358 RITKESETHAVGKSQDKGIE-IKGPSSGNRNITKEVGKGNEGKEDKGQHGMILGKGNVKT 416
Query: 93 SGSSIAQGGSAGSFKPGT--GYSQVSYSSGSGS---------SLQGASGSSQLGSSSSHS 141
G + G +PG G+S S S S+QG +S S+ +
Sbjct: 417 QGEVVNIEGPGQKSEPGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDD 476
Query: 142 GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS----ALPTNDNSYRGILNPSQPGQSSS 197
+S S + SSS +S + S S GNGS A + +S N G ++
Sbjct: 477 ANSESDNNSSSRGDASYN----SDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNN 532
Query: 198 SSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVV 257
+ S SG+ S + SSD +S S S S SS S S
Sbjct: 533 GNDDNDKSDSGKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDS----S 588
Query: 258 DQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGK 317
D S + S+ S D + SSDS + S
Sbjct: 589 DSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSS 648
Query: 318 IYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGV 377
+ ++ + S ++ S SSN S S+ SS + +
Sbjct: 649 DSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSS 708
Query: 378 QLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSS 437
S+ S S S SS S SS+ +S S S + S +SS SS
Sbjct: 709 DSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSS 768
Query: 438 QSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSA 491
SS S SS S + S S + D S D S + SS +
Sbjct: 769 DSSD-------SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDS 815
Score = 40.0 bits (92), Expect = 0.005
Identities = 31/83 (37%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
DSS S S SS S S S+ SS S +SS SS + S+ S S SG
Sbjct: 1218 DSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSD-SSDSTSDSNDESDSQSKSG 1276
Query: 121 SGSSLQGASGSSQLGSSSSHSGS 143
+G++ S S GS S+HS S
Sbjct: 1277 NGNNNGSDSDSDSEGSDSNHSTS 1299
>gi|62122917 filaggrin family member 2 [Homo sapiens]
Length = 2391
Score = 84.7 bits (208), Expect = 2e-16
Identities = 137/470 (29%), Positives = 174/470 (37%), Gaps = 54/470 (11%)
Query: 56 LTGKGDSSGF---SSYSGSSSSGS-SISSARSSGGGSSGSSSGSS-------IAQGGSAG 104
++G G SSGF S SG SS G S++SSG G GSSSG + ++ G S+
Sbjct: 672 VSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSGQSSS 731
Query: 105 SFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSS--GSHSGSSSSHSSSSSSFQ 162
+ G+G Q SSG G G+ SS G S SG S G HS SS S
Sbjct: 732 FGQHGSGSGQ---SSGFGQHGSGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGS 788
Query: 163 FSSSSF-QVGNGSALPTNDNSYRGILNPS----QPGQSSSSSQTFG-------VSSSGQS 210
+S F Q G+GS+ T Y S Q G S S FG SS GQ
Sbjct: 789 RQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQH 848
Query: 211 VSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQG 270
S + + SS S G S G + SS SG QHGSG+ G G
Sbjct: 849 GSGSSQ--SSGYGQHGSSSGQ-TSGFGQHRSSSGQYSG--------FGQHGSGS-GQSSG 896
Query: 271 ---PPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKE 327
+G G S SYG + S Y G S G+ + G
Sbjct: 897 FGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGS--SSGQTFGFGQHRSG 954
Query: 328 NPVKGSPGVPSFAAGPPISEGKYFS---SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGS 384
+ G +G G++ S + + SS + G+G Q G G
Sbjct: 955 SGQSSGFGQHGSGSGQSSGFGQHESGSGKSSGFGQHESRSSQSNYGQHGSGSSQSSGYGQ 1014
Query: 385 TGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSS----SSQSS 440
GS + + SSS SG H GS S GTGS SS S+S
Sbjct: 1015 HGSSSGQTTGFGQHRSSS--GQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSR 1072
Query: 441 GKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
Q S SSG+ +S +G P S+G GS S
Sbjct: 1073 QSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGS 1122
Score = 80.9 bits (198), Expect = 3e-15
Identities = 137/470 (29%), Positives = 166/470 (35%), Gaps = 69/470 (14%)
Query: 57 TGKGDSSGFSSY---SGSSSSGS-SISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGY 112
+G G SSGF + SG SS G S S++SSG G GS S Q GS S TG+
Sbjct: 750 SGSGQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSS--QSTGF 807
Query: 113 SQVSYSSGSGSSL---QGASGSSQLGS-----SSSHSGSSGSHSGSSSSHSSSSSSFQFS 164
Q Y SGSG S Q SGS Q S SH S G H GS SS SS Q
Sbjct: 808 GQ--YGSGSGQSAGFGQHGSGSGQSSGFGQHESRSHQSSYGQH-GSGSSQSSGYG--QHG 862
Query: 165 SSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGV--SSSGQSVSSNQRPCSSDI 222
SSS Q ++ Y G Q G S S FG + SGQ Q S
Sbjct: 863 SSSGQTSGFGQHRSSSGQYSGF---GQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSH- 918
Query: 223 PDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKP 282
S G S S Y H S GQ QH SG+ G G G
Sbjct: 919 QSSYGQHGSGSSQSSGY--GQHGSSSGQ---TFGFGQHRSGS-GQSSGFGQHGSG----- 967
Query: 283 CPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAG 342
+ +G +E G S + G S+ G + G ++G
Sbjct: 968 ----SGQSSGFGQHESGSGKSSGF---GQHESRSSQSNYGQHGSGSSQSSGYGQHGSSSG 1020
Query: 343 PPISEGKYFSSNPIIPS----QSAASSAIAFQPVGTGGVQLCGGG---------STGSKG 389
G++ SS+ S + + F GTG Q G G S G G
Sbjct: 1021 QTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHG 1080
Query: 390 PCSPSSSRVPSSSSISS-SSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPC 448
S SS S S +SG H GS S G G + S S QSSG
Sbjct: 1081 SGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSS-----GFGQY-GSGSGQSSG------F 1128
Query: 449 GSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRS 498
G S +G +G H S+ + CG +G P S
Sbjct: 1129 GQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTS 1178
Score = 75.9 bits (185), Expect = 9e-14
Identities = 106/405 (26%), Positives = 137/405 (33%), Gaps = 29/405 (7%)
Query: 57 TGKGDSSGFSSYSGSSSSG---SSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYS 113
+G SSG+ Y +SG + S +S+G G GS SG S G +G+
Sbjct: 548 SGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGSGQSSGFG 607
Query: 114 QVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF-QFSSSSFQ-VG 171
Q SG S Q +SGSSQ H S G S SS S+ F Q+ S S Q G
Sbjct: 608 QHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVS-SSGQSVSSNQRPCSSDIPDSPCSGG 230
G + + S + S+ G SS FG S SSG + +S S G
Sbjct: 668 FGQHVSGSGQSSGFGQHESRSGHSSYGQHGFGSSQSSGYGQHGSSSGQTSGFGQHELSSG 727
Query: 231 PIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVD 290
S H GQ QHGSG +G G S
Sbjct: 728 QSSSF------GQHGSGSGQSS---GFGQHGSG-----------SGQSSGFGQHESRSGQ 767
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
SYG + S Y G + G G + ++ G G S + G
Sbjct: 768 SSYGQHSSGSSQSSGYGQHGSRQTSG-FGQHGSGSSQSTGFGQYGSGSGQSAGFGQHGSG 826
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGL 410
+ + S ++ G+G Q G G GS +S SS SG
Sbjct: 827 SGQSSGFGQHESRSHQSSYGQHGSGSSQSSGYGQHGSSS--GQTSGFGQHRSSSGQYSGF 884
Query: 411 PYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSS 455
H GS S GTGS S Q + G S S
Sbjct: 885 GQHGSGSGQSSGFGQHGTGSGQYSGFGQHESRSHQSSYGQHGSGS 929
Score = 66.6 bits (161), Expect = 5e-11
Identities = 67/205 (32%), Positives = 84/205 (40%), Gaps = 20/205 (9%)
Query: 57 TGKGDSSGFSSYSGSSSSGS----SISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGY 112
TG G SSGF Y S S S++SSG G GS+SG Q G +PG+G
Sbjct: 1056 TGSGQSSGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSG----QTSGFGQHRPGSGQ 1111
Query: 113 SQ--VSYSSGSGSSL---QGASGSSQLGSSSSHSGSSGSHS----GSSSSHSSSSSSFQF 163
S Y SGSG S Q SG+ + + H SG S G+ SS SS +
Sbjct: 1112 SSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHE- 1170
Query: 164 SSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIP 223
S S G + +DN + S GQS+ Q +G S SGQS Q
Sbjct: 1171 SGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQ-YG-SGSGQSTGLGQGESQQVES 1228
Query: 224 DSPCSGGPIVSHSGPYIPSSHSVSG 248
S G +H + HS SG
Sbjct: 1229 GSTVHGRQETTHGQTINTTRHSQSG 1253
Score = 62.0 bits (149), Expect = 1e-09
Identities = 127/427 (29%), Positives = 151/427 (35%), Gaps = 59/427 (13%)
Query: 57 TGKGDSSGFSSY-------SGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPG 109
TG SSGF + G S SS S G SSG +SG Q GS G
Sbjct: 434 TGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSG--FGQHGSGSGQSSG 491
Query: 110 TGYSQVSYSSGSGSSLQGASGSSQLGSSSSHS---GSSGSHSGSSSSHSSSSSSFQFSSS 166
G SGSG S SG Q GS S S G GS SG SS S + SS
Sbjct: 492 FG----QCGSGSGQS----SGFGQHGSVSGQSSGFGQHGSVSGQSSGFGQHESRSR-QSS 542
Query: 167 SFQVGNGSALPTNDNSY--RGILNPSQPGQSSSSSQTFGV--SSSGQSVSSNQRPCSSDI 222
Q G+GS+ + Y R Q G S S FG S SGQS Q S
Sbjct: 543 YGQHGSGSSQSSGYGQYGSRETSGFGQHGLGSGQSTGFGQYGSGSGQSSGFGQHGSGS-- 600
Query: 223 PDSPCSG-GPIVSHSGPYIPSSHSVSGGQRP--------VVVVVDQHGSG-APGVVQGPP 272
SG G S SG HS Q QHGSG + G
Sbjct: 601 --GQSSGFGQHESRSGQSSYGQHSSGSSQSSGYGQHGSRQTSGFGQHGSGSSQSTGFGQY 658
Query: 273 CSNGGLPGKPCPPITSVDKS--YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPV 330
S G ++ +S +G +E G S SY G S+ Y G +
Sbjct: 659 GSGSGQSSGFGQHVSGSGQSSGFGQHESRSGHS-SYGQHGFGSSQSSGY--GQHGSSSGQ 715
Query: 331 KGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP 390
G ++G S G++ S + + F G+G Q G G S+
Sbjct: 716 TSGFGQHELSSGQSSSFGQH---------GSGSGQSSGFGQHGSGSGQSSGFGQHESR-- 764
Query: 391 CSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQ-SSGKIILQPCG 449
S SS SS S SSG H GS S G+GS S+ Q SG G
Sbjct: 765 -SGQSSYGQHSSGSSQSSGYGQH--GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSAGFG 821
Query: 450 SKSSSSG 456
S SG
Sbjct: 822 QHGSGSG 828
Score = 60.8 bits (146), Expect = 3e-09
Identities = 109/411 (26%), Positives = 140/411 (34%), Gaps = 84/411 (20%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGS----AGSFKPGT 110
C +G G SG SG S+ S S G + G G ++ G+
Sbjct: 317 CQSGIKGGQGHGCVSGGQPSGCG--QPESNPCSQSYSQRGYGARENGQPQNCGGQWRTGS 374
Query: 111 GYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS----SSHSSSSSSFQ---- 162
S GSG S ++G + GS S SS S+ S S SS S+SF+
Sbjct: 375 SQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSFEQHGT 434
Query: 163 --FSSSSFQ---VGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
SS F+ G+G ++++ L Q G SS + FG SG SS
Sbjct: 435 GLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQSSGFGQ 494
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGG 277
C S S G SVSG G G G V G G
Sbjct: 495 CGSGSGQSSGFG------------QHGSVSG---------QSSGFGQHGSVSGQSSGFGQ 533
Query: 278 LPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVP 337
+ S SYG + S Y G+ Y ++E G G+
Sbjct: 534 HESR------SRQSSYGQHGSGSSQSSGY---------GQ-----YGSRETSGFGQHGLG 573
Query: 338 SFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSR 397
S G G+Y S + + F G+G Q G G S+ S SS
Sbjct: 574 S---GQSTGFGQY---------GSGSGQSSGFGQHGSGSGQSSGFGQHESR---SGQSSY 618
Query: 398 VPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSS-------SSSSQSSG 441
SS S SSG H GS S G+GS S S S QSSG
Sbjct: 619 GQHSSGSSQSSGYGQH--GSRQTSGFGQHGSGSSQSTGFGQYGSGSGQSSG 667
Score = 58.2 bits (139), Expect = 2e-08
Identities = 59/176 (33%), Positives = 73/176 (41%), Gaps = 24/176 (13%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG----------SSIAQGGSAGSF 106
+ G SGF G SGS SS G SG SSG SS Q GS S
Sbjct: 1030 SSSGQYSGF----GQHGSGSDQSSGFGQHGTGSGQSSGFGQYESRSRQSSYGQHGSGSSQ 1085
Query: 107 KPGTGY--SQVSYSSGSGSSLQG---ASGSSQLGSSSSHSGSSGSH-SGSSSSHSSSSSS 160
G G S +SG G G +SG Q GS S S G H SG+ S +
Sbjct: 1086 SSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYGSGSGQSSGFGQHGSGTGKSSGFAQHE 1145
Query: 161 FQFSSSSF-QVGNGSALPTNDNSYRGILNPSQP-GQSSSSSQTFGVSSSGQSVSSN 214
++ SS+ Q G GS+ + + P+ GQ S S F SSSGQ +S +
Sbjct: 1146 YRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSFGQHVSGSDNF--SSSGQHISDS 1199
Score = 55.8 bits (133), Expect = 9e-08
Identities = 64/206 (31%), Positives = 86/206 (41%), Gaps = 22/206 (10%)
Query: 62 SSGFSSYSGSS--SSGSSISSARSSGGGSSGSSSGSSIA-----QGGSAGSFKPGTGYSQ 114
SSG S YS S S S +R G +GS G S + G + G +G+SQ
Sbjct: 1800 SSGHSEYSDSEGHSGFSQRPHSRGHTHGQAGSQHGESESIVDERHGTTHGQTGDTSGHSQ 1859
Query: 115 VSY--SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSS----F 168
+ S+ SGSS G S SS S S GSH+ S +HS + S S S+
Sbjct: 1860 SGHGQSTQSGSSTTGRRRSGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRH 1919
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQS-VSSNQRPCSSDIPDSPC 227
Q +G T D + G +PS + S+T G SG S S ++ P S
Sbjct: 1920 QTTHGQ---TGDTTEHG--HPSHGQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSGH 1974
Query: 228 SGGPIVSH---SGPYIPSSHSVSGGQ 250
+ G SH SG + H + GQ
Sbjct: 1975 THGQAGSHYPESGSSVHERHGTTHGQ 2000
Score = 52.4 bits (124), Expect = 1e-06
Identities = 63/204 (30%), Positives = 77/204 (37%), Gaps = 30/204 (14%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGG---------GSSGSSSGSSIAQGGSAGSFK 107
+G SSG+ + SS + RSS G S SSG GS S
Sbjct: 1004 SGSSQSSGYGQHGSSSGQTTGFGQHRSSSGQYSGFGQHGSGSDQSSGFGQHGTGSGQS-- 1061
Query: 108 PGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSH--SSSSSSF-QFS 164
+G+ Q S S Q SGSSQ H +SG SG S SS F Q+
Sbjct: 1062 --SGFGQYESRSRQSSYGQHGSGSSQSSGYGQHGSNSGQTSGFGQHRPGSGQSSGFGQYG 1119
Query: 165 SSSFQ--------VGNGSALPTNDNSYR-GILNPSQPGQSSSSSQTFG--VSSSGQSVSS 213
S S Q G G + + YR G + Q G SS S G S SG + S
Sbjct: 1120 SGSGQSSGFGQHGSGTGKSSGFAQHEYRSGQSSYGQHGTGSSQSSGCGQHESGSGPTTSF 1179
Query: 214 NQRPCSSDIPDSPCSGGPIVSHSG 237
Q S D+ S G +S SG
Sbjct: 1180 GQHVSGS---DNFSSSGQHISDSG 1200
Score = 52.4 bits (124), Expect = 1e-06
Identities = 65/243 (26%), Positives = 90/243 (37%), Gaps = 55/243 (22%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSS-------------------SGSSI 97
TG+ G S + S+ GS + R SG S S +GS
Sbjct: 1395 TGEATGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQH 1454
Query: 98 AQGGSAGSFKPGTGYSQVS-----------YSSGSGSSLQGASGSSQLGSSSSHSGSSGS 146
+ GS + GT + Q S+ GSS G GS SS S S GS
Sbjct: 1455 GESGSTVHGRHGTTHGQTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGGS 1514
Query: 147 HSGSSSSHSSSSSSFQFSSS----SFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF 202
H+ S +H S S S S ++ +G T +SY G +Q G S+T
Sbjct: 1515 HTHSGHTHGQSGSQHGESESIIHDRHRITHGQTGDTTRHSYSGHEQTTQTG-----SRTT 1569
Query: 203 GVSSSGQSVSSNQRPCSSDIPDSPC-SGGPIVSHSGPYIPSSHSVSGGQ--RPVVVVVDQ 259
G QR S+ DS SGG HS + ++ +G Q P V ++
Sbjct: 1570 G----------RQRTSHSESTDSEVHSGGSHRPHSREH---TYGQAGSQHEEPEFTVHER 1616
Query: 260 HGS 262
HG+
Sbjct: 1617 HGT 1619
Score = 50.8 bits (120), Expect = 3e-06
Identities = 61/200 (30%), Positives = 82/200 (41%), Gaps = 32/200 (16%)
Query: 63 SGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS---- 118
SG S YS S S +S S G + +GS + GS+ + GT + Q + +
Sbjct: 1953 SGHSEYSDSEGP-SGVSHTHS---GHTHGQAGSHYPESGSSVHERHGTTHGQTADTTRHG 2008
Query: 119 -SGSGSSLQG--------ASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQ 169
SG G S Q ASG S+ S HSG S +HSG +H + S S SS
Sbjct: 2009 HSGHGQSTQRGSRTTGRRASGHSEYSDSEGHSGVSHTHSG--HAHGQAGSQHGESGSSVH 2066
Query: 170 VGNGSALPTNDNSYRGILNPSQPGQSSS-SSQTFGVSSSGQSVSSNQRPCSSDIPDSPCS 228
+G+ ++ R S GQS+ S+T G SG S SS DS
Sbjct: 2067 ERHGTTHGQTGDTTRHA--HSGHGQSTQRGSRTAGRRGSGHSESS----------DSEVH 2114
Query: 229 GGPIVSHSGPYIPSSHSVSG 248
G +HSG + S G
Sbjct: 2115 SGVSHTHSGHTYGQARSQHG 2134
Score = 47.4 bits (111), Expect = 3e-05
Identities = 103/430 (23%), Positives = 144/430 (33%), Gaps = 83/430 (19%)
Query: 90 GSSSG---SSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGS 146
G SG SS ++G G + G V GS S G G+ L SS + GS
Sbjct: 124 GHKSGYRHSSWSEGEEHG-YSSGHSRGTVKCRHGSNSRRLGRQGN--LSSSGNQEGSQKR 180
Query: 147 HSGSSSSHSSSSSSFQFSSSSFQ----VGNGSALPTNDN--SYRGILNPSQPGQSSSSSQ 200
+ SS HS S + SSS + + P+ ++ Y + +
Sbjct: 181 YHRSSCGHSWSGGKDRHGSSSVELRERINKSHISPSRESGEEYESGSGSNSWERKGHGGL 240
Query: 201 TFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQH 260
+ G+ +SG +S Q S CSG S G+R H
Sbjct: 241 SCGLETSGHESNSTQSRIREQKLGSSCSG---------------SGDSGRR-------SH 278
Query: 261 GSGAPGVVQGPPCSNGGLPGKPCPPITSVDK-SYGGYEVVGGSSDSYLVPGMTYSKGKIY 319
G SN G+P +S +GG G+ SY+ G
Sbjct: 279 ACG---------YSNSSGCGRPQNASSSCQSHRFGGQ----GNQFSYIQSGC-------- 317
Query: 320 PVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIP--SQSAASSAIAFQPVGTGG- 376
++ +KG G + G P G+ SNP SQ + QP GG
Sbjct: 318 -------QSGIKGGQGHGCVSGGQPSGCGQP-ESNPCSQSYSQRGYGARENGQPQNCGGQ 369
Query: 377 -------VQLCGGGSTGSKGPCS------PSSSRVPSSSSISSSSGLPYHPCGSASQSPC 423
CG +G CS S R +SSS + S + GS+ +
Sbjct: 370 WRTGSSQSSCCGQYGSGGSQSCSNGQHEYGSCGRFSNSSSSNEFSKCDQYGSGSSQSTSF 429
Query: 424 SPPGTGSFSSSSSSQ---SSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS 480
GTG SS Q SG+ Q + S S G+ SS +G S
Sbjct: 430 EQHGTGLSQSSGFEQHVCGSGQTCGQHESTSSQSLGYDQHGSSSGKTSGFGQHGSGSGQS 489
Query: 481 AGAKPCGSSS 490
+G CGS S
Sbjct: 490 SGFGQCGSGS 499
Score = 47.4 bits (111), Expect = 3e-05
Identities = 56/203 (27%), Positives = 81/203 (39%), Gaps = 36/203 (17%)
Query: 62 SSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS--- 118
+SG S YS S S +S S G + +GS + GS+ + GT + Q +
Sbjct: 2027 ASGHSEYSDSEGH-SGVSHTHS---GHAHGQAGSQHGESGSSVHERHGTTHGQTGDTTRH 2082
Query: 119 --SGSGSSLQGAS--------GSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
SG G S Q S G S+ S HSG S +HSG H+ + Q S
Sbjct: 2083 AHSGHGQSTQRGSRTAGRRGSGHSESSDSEVHSGVSHTHSG----HTYGQARSQHGES-- 2136
Query: 169 QVGNGSALPTNDNSYRGIL-NPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPC 227
GSA+ + G + ++ GQS T +G + QR S+ DS
Sbjct: 2137 ----GSAIHGRQGTIHGQTGDTTRHGQSGHGQST----QTGSRTTGRQRSSHSESSDSEV 2188
Query: 228 SGGPIVSHSGPYIPSSHSVSGGQ 250
+HSG +HS +G +
Sbjct: 2189 HSEASPTHSG----HTHSQAGSR 2207
Score = 46.2 bits (108), Expect = 7e-05
Identities = 68/226 (30%), Positives = 87/226 (38%), Gaps = 39/226 (17%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGG-SAGSFKPGTGYSQV 115
TG SSG + S SG + S + G + SSSG I+ G S G + G+G Q
Sbjct: 1158 TGSSQSSGCGQHE--SGSGPTTSFGQHVSGSDNFSSSGQHISDSGQSTGFGQYGSGSGQ- 1214
Query: 116 SYSSGSGSSLQGASGSSQLGSSSSHSGS-------SGSHSGSS------------SSHSS 156
S G G S Q SGS+ G + G S S G S SS S
Sbjct: 1215 STGLGQGESQQVESGSTVHGRQETTHGQTINTTRHSQSGQGQSTQTGSRVTRRRRSSQSE 1274
Query: 157 SSSSFQFS------SSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQS 210
+S S S S GS P + ++ R + GQ +++ G S GQS
Sbjct: 1275 NSDSEVHSKVSHRHSEHIHTQAGSHYPKSGSTVRRRQGTTH-GQRGDTTR-HGHSGHGQS 1332
Query: 211 ------VSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQ 250
S QR SD DS G VSH +HS +G Q
Sbjct: 1333 TQTGSRTSGRQRFSHSDATDSEVHSG--VSHRPHSQEQTHSQAGSQ 1376
Score = 45.8 bits (107), Expect = 1e-04
Identities = 51/164 (31%), Positives = 70/164 (42%), Gaps = 12/164 (7%)
Query: 57 TGKGDSSGFSSYSGSSS--SGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
+G +SS +SG S SG + ARS G S + G G G G S
Sbjct: 2103 SGHSESSDSEVHSGVSHTHSGHTYGQARSQHGESGSAIHGRQGTIHGQTGD-TTRHGQSG 2161
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSS--HSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG- 171
S+ +GS G SS SS S HS +S +HSG + S + S SS + G
Sbjct: 2162 HGQSTQTGSRTTGRQRSSHSESSDSEVHSEASPTHSGHTHSQAGSRHGQSGSSGHGRQGT 2221
Query: 172 -NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSN 214
+G T +++ G +Q G S+T G SG S SS+
Sbjct: 2222 THGQTGDTTRHAHYGYGQSTQRG-----SRTTGRRGSGHSESSD 2260
Score = 44.7 bits (104), Expect = 2e-04
Identities = 57/199 (28%), Positives = 84/199 (42%), Gaps = 24/199 (12%)
Query: 57 TGKGDSSGFSSYSGSSS--SGSSISSARSSGGGSSGSSSGSSIAQGGSAG-SFKPGTGYS 113
+G +SS +SG S SG + S ARS G S + G G + + G
Sbjct: 1878 SGHSESSDSEVHSGGSHTHSGHTHSQARSQHGESESTVHKRHQTTHGQTGDTTEHGHPSH 1937
Query: 114 QVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
+ +GS ++ + SG S+ S SG S +HSG +H + S + S SS +G
Sbjct: 1938 GQTIQTGSRTTGRRGSGHSEYSDSEGPSGVSHTHSG--HTHGQAGSHYPESGSSVHERHG 1995
Query: 174 SAL-PTNDNSYRGILNPSQPGQSSS-SSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGP 231
+ T D + G S GQS+ S+T G +SG S+ DS G
Sbjct: 1996 TTHGQTADTTRHG---HSGHGQSTQRGSRTTGRRASGH----------SEYSDSEGHSGV 2042
Query: 232 IVSHSGPYIPSSHSVSGGQ 250
+HSG +H +G Q
Sbjct: 2043 SHTHSG----HAHGQAGSQ 2057
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/199 (26%), Positives = 77/199 (38%), Gaps = 19/199 (9%)
Query: 62 SSGFSSYSGSSSSGSSISSA---RSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
+SG +S S ++ S + S R + S +GS + S + T Y Q +
Sbjct: 1339 TSGRQRFSHSDATDSEVHSGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEA 1398
Query: 119 SGSGSSLQGAS---GSSQLG-SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG-NG 173
+G G S G S GS G S HS SS S S SH S + Q G +G
Sbjct: 1399 TGHGHSGHGQSTQRGSRTTGRRGSGHSESSDSEVHSGGSHRPQSQEQTHGQAGSQHGESG 1458
Query: 174 SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSS--GQSVSSNQRPCSSDIPDSPCSGGP 231
S + + G Q G ++ + S+ G S + + S+ DS G
Sbjct: 1459 STVHGRHGTTHG-----QTGDTTRHAHYHHGKSTQRGSSTTGRRGSGHSESSDSEVHSGG 1513
Query: 232 IVSHSGPYIPSSHSVSGGQ 250
+HSG +H SG Q
Sbjct: 1514 SHTHSG----HTHGQSGSQ 1528
Score = 38.5 bits (88), Expect = 0.015
Identities = 62/235 (26%), Positives = 95/235 (40%), Gaps = 35/235 (14%)
Query: 62 SSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP---GTGYSQ---- 114
++G S S SS S + S S +G + G + +Q G + S P GT + Q
Sbjct: 1645 TTGRQRSSHSESSDSEVHSGVSHT--HTGHTHGQAGSQHGQSESIVPERHGTTHGQTGDT 1702
Query: 115 ---------VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSS 165
++ +GS ++ + SG S+ S +SG S +HSG +H + S S
Sbjct: 1703 TRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHSG--HTHGQARSQHGESE 1760
Query: 166 SSFQVGNGSALPTNDNSYRGILNPSQPGQSS-SSSQTFGVSSSGQSVSSNQRPCSSDIPD 224
S +G+ ++ R S GQS+ + S+T G SSG S S+ S
Sbjct: 1761 SIVHERHGTIHGQTGDTTRHA--HSGHGQSTQTGSRTTGRRSSGHSEYSDSEG-HSGFSQ 1817
Query: 225 SPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGS--GAPGVVQGPPCSNGG 277
P S G +G S S +V ++HG+ G G G S G
Sbjct: 1818 RPHSRGHTHGQAGSQHGESES---------IVDERHGTTHGQTGDTSGHSQSGHG 1863
Score = 37.0 bits (84), Expect = 0.045
Identities = 36/116 (31%), Positives = 47/116 (40%), Gaps = 15/116 (12%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS----GSSIAQG---GSAGSFK-- 107
TG Y S+ GS + R SG S S GS G G AGS +
Sbjct: 2226 TGDTTRHAHYGYGQSTQRGSRTTGRRGSGHSESSDSEVHSWGSHTHSGHIQGQAGSQQRQ 2285
Query: 108 PGT---GYSQVSYSSGSGSSLQGASG---SSQLGSSSSHSGSSGSHSGSSSSHSSS 157
PG+ G + ++ ++ G SG S+Q GS SS + SHS H SS
Sbjct: 2286 PGSTVHGRLETTHGQTGDTTRHGHSGYGQSTQTGSRSSRASHFQSHSSERQRHGSS 2341
Score = 33.5 bits (75), Expect = 0.49
Identities = 51/206 (24%), Positives = 79/206 (38%), Gaps = 25/206 (12%)
Query: 72 SSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGS-------FKPGTGYSQVSYSSGSGSS 124
+S S S SGG S + Q GS + GT + Q+ ++G S
Sbjct: 1574 TSHSESTDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHS 1633
Query: 125 LQGAS---GSSQLG-SSSSHSGSSGS--HSGSSSSHSSSSSSFQFSSSSFQVGNGSALPT 178
G S GS G SSHS SS S HSG S +H+ + + S + S +P
Sbjct: 1634 GHGQSTQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHG---QAGSQHGQSESIVPE 1690
Query: 179 NDNSYRGILNPSQPGQSSSSSQTFG--VSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHS 236
+ G Q G ++ + + +G + + S+ DS G +HS
Sbjct: 1691 RHGTTHG-----QTGDTTRHAHYHHGLTTQTGSRTTGRRGSGHSEYSDSEGYSGVSHTHS 1745
Query: 237 GPYIPSSHSVSGGQRPVVVVVDQHGS 262
G + S G +V ++HG+
Sbjct: 1746 GHTHGQARSQHGESES--IVHERHGT 1769
Score = 30.8 bits (68), Expect = 3.2
Identities = 46/177 (25%), Positives = 63/177 (35%), Gaps = 15/177 (8%)
Query: 87 GSSGSSSGSSIA--QGGSAGSFKPGT--GYSQVSYSSGSGSSLQGASGSSQLGSSSSHSG 142
GS SGS++ QG + G T G+S S+ +GS G S ++ S
Sbjct: 1297 GSHYPKSGSTVRRRQGTTHGQRGDTTRHGHSGHGQSTQTGSRTSGRQRFSHSDATDSEVH 1356
Query: 143 SSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSS-SSQT 201
S SH S + S + Q S V S GQS+ S+T
Sbjct: 1357 SGVSHRPHSQEQTHSQAGSQHGESESTVHERHETTYGQTGEATGHGHSGHGQSTQRGSRT 1416
Query: 202 FGVSSSGQSVSS--------NQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQ 250
G SG S SS + RP S + + G SG + H + GQ
Sbjct: 1417 TGRRGSGHSESSDSEVHSGGSHRPQSQE--QTHGQAGSQHGESGSTVHGRHGTTHGQ 1471
Score = 29.3 bits (64), Expect = 9.3
Identities = 33/108 (30%), Positives = 43/108 (39%), Gaps = 14/108 (12%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSI-----AQGGSAGSFKPGTGYSQVSY--S 118
S+ S S GS +R G +GS G + G TG+S + S
Sbjct: 1579 STDSEVHSGGSHRPHSREHTYGQAGSQHEEPEFTVHERHGTTHGQIGDTTGHSHSGHGQS 1638
Query: 119 SGSGSSLQGASGSSQLGSSSS--HSGSSGSHSG-----SSSSHSSSSS 159
+ GS G SS SS S HSG S +H+G + S H S S
Sbjct: 1639 TQRGSRTTGRQRSSHSESSDSEVHSGVSHTHTGHTHGQAGSQHGQSES 1686
>gi|169658378 trinucleotide repeat containing 18 [Homo sapiens]
Length = 2968
Score = 75.9 bits (185), Expect = 9e-14
Identities = 80/232 (34%), Positives = 94/232 (40%), Gaps = 53/232 (22%)
Query: 29 GTLAKSIG---TFSDPC--KDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARS 83
G LA+ G TF D K P + + D G SS S SS S SS SS+ S
Sbjct: 2523 GDLAQEPGPGLTFEDSGNPKSPDKAQAEQD------GAEESESSSSSSSGSSSSSSSSSS 2576
Query: 84 SGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGS 143
SG + G G GG + + S + S S SS +S SS SSSS S S
Sbjct: 2577 SGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSSSSSSSSS 2636
Query: 144 SGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFG 203
S S S SSSS SSSSSS SSSS SSSSS
Sbjct: 2637 SSSSSSSSSSSSSSSSSSSSSSSS---------------------------SSSSS---- 2665
Query: 204 VSSSGQSVSSNQRPCSSDIPDSPC-SGGP---------IVSHSGPYIPSSHS 245
SSS S + CSSD +P + GP +G PS+HS
Sbjct: 2666 -SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHS 2716
Score = 72.0 bits (175), Expect = 1e-12
Identities = 73/223 (32%), Positives = 86/223 (38%), Gaps = 30/223 (13%)
Query: 2 GSS--RAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGK 59
GSS +APW G LA PG + G P K + +
Sbjct: 2509 GSSEPKAPWPKATDGD------LAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEESESSSS 2562
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSG-GGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
S SS S SSSSGS G G +G S+ + P + S S S
Sbjct: 2563 SSSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSS 2622
Query: 119 SGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS---- 174
S S SS +S SS SSSS S SS S S SSSS SSSSSS SSSS + S
Sbjct: 2623 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSD 2682
Query: 175 ---------------ALPTNDNSYRGILNPS--QPGQSSSSSQ 200
ALPT G PS PG+ + + Q
Sbjct: 2683 DEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQ 2725
Score = 54.3 bits (129), Expect = 3e-07
Identities = 52/150 (34%), Positives = 66/150 (44%), Gaps = 9/150 (6%)
Query: 352 SSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLP 411
SS S S++SS + G GG TG + CS +SSR S +S SSSS
Sbjct: 2564 SSGSSSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRN-CSAASSRAASPASSSSSSS-- 2620
Query: 412 YHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGP 471
S+S S S + S SSSSSS SS S SSSS S SS + T
Sbjct: 2621 --SSSSSSSSSSSSSSSSSSSSSSSSSSSSS---SSSSSSSSSSSSSSSSSSSSSSTTDE 2675
Query: 472 DGSPHPDPSAGAKP-CGSSSAGKIPCRSIR 500
D S D A P G S+ +P ++ +
Sbjct: 2676 DSSCSSDDEAAPAPTAGPSAQAALPTKATK 2705
Score = 51.2 bits (121), Expect = 2e-06
Identities = 60/211 (28%), Positives = 75/211 (35%), Gaps = 14/211 (6%)
Query: 77 SISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGS 136
S+ S + G S + G A PG + + G+ + S
Sbjct: 2500 SLGSYPPAAGSSEPKAPWPKATDGDLAQEPGPGLTFEDSGNPKSPDKAQAEQDGAEE--S 2557
Query: 137 SSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSS 196
SS S SSGS S SSSS SSS S + + G+G N + P SS
Sbjct: 2558 ESSSSSSSGS-SSSSSSSSSSGSETEGEEEGDKNGDGGCGTGGRNCSAASSRAASPASSS 2616
Query: 197 SSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVV 256
SSS + SSS S SS+ SS S S S S SS S S
Sbjct: 2617 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS----T 2672
Query: 257 VDQHGS------GAPGVVQGPPCSNGGLPGK 281
D+ S AP G P + LP K
Sbjct: 2673 TDEDSSCSSDDEAAPAPTAG-PSAQAALPTK 2702
Score = 43.9 bits (102), Expect = 4e-04
Identities = 66/236 (27%), Positives = 83/236 (35%), Gaps = 44/236 (18%)
Query: 310 GMTYSKGKIYPVGYFTKENPVKGSPGVP----SFAAGPPISEGKYFSSNPIIPSQSAASS 365
G+T K K +E+P G P S + PP + SS P P A
Sbjct: 2468 GVTSPKSKKAKEALLLREDPGAGGWQEPKSLLSLGSYPPAAG----SSEPKAPWPKATDG 2523
Query: 366 AIAFQPVGTGGVQLCGGG----------STGSKGPCSPSSSRVPSSSSISSSS------- 408
+A +P G G G G++ S SSS SSSS SSSS
Sbjct: 2524 DLAQEP-GPGLTFEDSGNPKSPDKAQAEQDGAEESESSSSSSSGSSSSSSSSSSSGSETE 2582
Query: 409 -------------GLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSS 455
G C +AS SP + S SSSSSS SS S SSSS
Sbjct: 2583 GEEEGDKNGDGGCGTGGRNCSAASSRAASPASSSSSSSSSSSSSSSS-----SSSSSSSS 2637
Query: 456 GHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRSIRDILAQVKPLGP 511
S SS + + S S+ + SS+ + S D A GP
Sbjct: 2638 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTTDEDSSCSSDDEAAPAPTAGP 2693
Score = 37.4 bits (85), Expect = 0.034
Identities = 41/182 (22%), Positives = 63/182 (34%), Gaps = 8/182 (4%)
Query: 352 SSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLP 411
SS P+ S++SS+ + + S+ S S SSS SSSS SSSS
Sbjct: 2606 SSRAASPASSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2665
Query: 412 YHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGP 471
S + S + + ++ S + L +K + P
Sbjct: 2666 SSSSSSTTDEDSSCSSDDEAAPAPTAGPSAQAALPTKATKQAGKARPSAHSPGKKTPAPQ 2725
Query: 472 DGSPHPDPSAGAKPCGSSSAGKIPCRSIRDILAQVKPLGPQLADPEV--------FLPQG 523
+P P P+ +P + A P + L K L + P V FLP
Sbjct: 2726 PQAPPPQPTQPLQPKAQAGAKSRPKKREGVHLPTTKELAKRQRLPSVENRPKIAAFLPAR 2785
Query: 524 EL 525
+L
Sbjct: 2786 QL 2787
>gi|109255251 loricrin [Homo sapiens]
Length = 312
Score = 73.6 bits (179), Expect = 4e-13
Identities = 76/231 (32%), Positives = 89/231 (38%), Gaps = 20/231 (8%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
C G G S +S GSS GS S S GGGS SSG + GG +G F G G S
Sbjct: 80 CGGGSGGSVKYSGGGGSSGGGSGCFS--SGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSS 137
Query: 115 VSYS---SGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
S S G G + Q S GSSG SG SS S +S G
Sbjct: 138 GGGSGCFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSGCG 197
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQ-TFGVSSSGQSVSSNQRPCSS--DIPDSPCS 228
GS + S G ++ Q Q+S + Q ++G SSG S SS S C
Sbjct: 198 GGS----SGGSGSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSGCG 253
Query: 229 GGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLP 279
GG SG I SV GG G G G G S G+P
Sbjct: 254 GGSSGIGSGCIISGGGSVCGG--------GSSGGGGGGSSVGGSGSGKGVP 296
Score = 73.2 bits (178), Expect = 6e-13
Identities = 93/292 (31%), Positives = 105/292 (35%), Gaps = 29/292 (9%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQ--GGSAGSFKPGTGYSQV 115
G G S G SS SG SG S GGGSSG G I GGS GS K YS
Sbjct: 38 GGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGSVK----YSGG 93
Query: 116 SYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
SSG GS + G SS GSSG SG SS SS S G S
Sbjct: 94 GGSSGGGSGCFSSGGGGSGCFSSGGGGSSGGGSGCFSSGGGGSSGGGSGCFSSGGGGFSG 153
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSH 235
SY G+ S G S S F G SV C S C GG
Sbjct: 154 QAVQCQSYGGV---SSGGSSGGGSGCFSSGGGGGSV------CGYSGGGSGCGGGSSGGS 204
Query: 236 SGPYIPSSH--SVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKS- 292
Y+ S S +P G G+ G G S GG C +S S
Sbjct: 205 GSGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGG--SGCFSSGGGGGSSGCGGGSSGIGSG 262
Query: 293 ---YGGYEVVGGSSDSYLVPGMTY---SKGKIYPVGYFTKENPVKGSPGVPS 338
GG V GG S G + GK P+ + T++ K +P PS
Sbjct: 263 CIISGGGSVCGGGSSGGGGGGSSVGGSGSGKGVPICHQTQQ---KQAPTWPS 311
Score = 63.2 bits (152), Expect = 6e-10
Identities = 96/353 (27%), Positives = 115/353 (32%), Gaps = 61/353 (17%)
Query: 78 ISSARSSGGGSSGSSSGSS----IAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQ 133
+ ++SGGG G SG GGS G G+ S YS G G S G G S
Sbjct: 14 VDCVKTSGGGGGGGGSGGGGCGFFGGGGSGG----GSSGSGCGYSGGGGYSGGGCGGGSS 69
Query: 134 LGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPG 193
G G G SG S +S S S F G G + G + G
Sbjct: 70 GGGGGGGIGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGS---------GCFSSGGGG 120
Query: 194 QSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPV 253
S S F SS G S C S SGG S S VS G
Sbjct: 121 SSGGGSGCF--SSGGGGSSGGGSGCFS-------SGGGGFSGQAVQCQSYGGVSSG---- 167
Query: 254 VVVVDQHGSGAPGVVQGPPC-SNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMT 312
G+ G G C S+GG G C GG GGS Y+
Sbjct: 168 ---------GSSG--GGSGCFSSGGGGGSVCGYSGGGSGCGGGSS--GGSGSGYVSSQQV 214
Query: 313 YSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPV 372
Y + GS G F++G G SS SS I +
Sbjct: 215 TQTSCAPQPSYGGGSSGGGGSGGSGCFSSG-----GGGGSS-----GCGGGSSGIGSGCI 264
Query: 373 GTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSP 425
+GG +CGGGS+G G S S S G+P Q+P P
Sbjct: 265 ISGGGSVCGGGSSGGGGGGS-------SVGGSGSGKGVPICHQTQQKQAPTWP 310
Score = 52.8 bits (125), Expect = 8e-07
Identities = 76/291 (26%), Positives = 93/291 (31%), Gaps = 37/291 (12%)
Query: 203 GVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGS 262
G S G S S C GG G I SGG V G
Sbjct: 40 GGSGGGSSGSGCGYSGGGGYSGGGCGGGSSGGGGGGGIGGCGGGSGGS-----VKYSGGG 94
Query: 263 GAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVG 322
G+ G G C + G G C S GG GG S + G S G G
Sbjct: 95 GSSG--GGSGCFSSGGGGSGC-------FSSGGGGSSGGGSGCFSSGGGGSSGGGS---G 142
Query: 323 YFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGG 382
F+ V + G S G + S S + G+G CGG
Sbjct: 143 CFSSGGGGFSGQAVQCQSYGGVSSGGSSGGGSGCFSSGGGGGSVCGYSGGGSG----CGG 198
Query: 383 GSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGK 442
GS+G G S SS ++ +S P G S G+G FSS SSG
Sbjct: 199 GSSGGSG------SGYVSSQQVTQTSCAPQPSYGGGSSGGGGSGGSGCFSSGGGGGSSG- 251
Query: 443 IILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGK 493
CG SS G C+ ++ GG G G S +GK
Sbjct: 252 -----CGGGSSGIGSGCIISGGGSVCGGGSSG----GGGGGSSVGGSGSGK 293
Score = 30.0 bits (66), Expect = 5.5
Identities = 34/123 (27%), Positives = 36/123 (29%), Gaps = 13/123 (10%)
Query: 373 GTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFS 432
G GG GGG G G S S G CG S G G
Sbjct: 22 GGGGGGGSGGGGCGFFGGGGSGGGSSGSGCGYSGGGGYSGGGCGGGSSG-----GGGGGG 76
Query: 433 SSSSSQSSGKIILQPCGSKSSSSGHPCMSV---SSLTLTGGPDGSPHPDPSAGAKPCGSS 489
SG + G SS G C S S + G GS S G C SS
Sbjct: 77 IGGCGGGSGGSVKYSGGGGSSGGGSGCFSSGGGGSGCFSSGGGGS-----SGGGSGCFSS 131
Query: 490 SAG 492
G
Sbjct: 132 GGG 134
>gi|161016767 mucin 21 [Homo sapiens]
Length = 566
Score = 70.5 bits (171), Expect = 4e-12
Identities = 120/509 (23%), Positives = 203/509 (39%), Gaps = 47/509 (9%)
Query: 20 LLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS 79
LL+ GLLL A + S + + S T G S S S ++ SGSS++
Sbjct: 9 LLMFGLLLHLEAATNSNETSTSANTGSSVISSGASTATNSGSSVTSSGVSTATISGSSVT 68
Query: 80 S------------ARSSGGGSSGSSSGSSIAQGGS-AGSFKPGTGYSQVSYSSGSGSSL- 125
S SSG ++ +S S+++ G S A + + T S S ++ S SS
Sbjct: 69 SNGVSIVTNSEFHTTSSGISTATNSEFSTVSSGISIATNSESSTTSSGASTATNSESSTP 128
Query: 126 -QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR 184
GAS ++ SS++ SG+S + + S SS +SS +S +S S +G++ TN S
Sbjct: 129 SSGASTATNSDSSTTSSGASTA-TNSDSSTTSSEASTATNSESSTTSSGASTATNSESST 187
Query: 185 GILNPSQPGQSSSSSQTFGVS----SSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI 240
S S SS+ + G S S ++ S+ ++ + SG ++S
Sbjct: 188 VSSRASTATNSESSTTSSGASTATNSESRTTSNGAGTATNSESSTTSSGASTATNSESST 247
Query: 241 PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG 300
PSS + G G+G + S+G I++V S G
Sbjct: 248 PSSGA--GTATNSESSTTSSGAGTATNSESSTVSSG---------ISTVTNSESSTPSSG 296
Query: 301 GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ 360
++ T S+ G T N + + A S ++ S+
Sbjct: 297 ANT-------ATNSESSTTSSGANTATNSDSSTTSSGASTATNSESSTTSSGASTATNSE 349
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ 420
S+ +S+ A +G G ST + S SS +S++ +S S +A+
Sbjct: 350 SSTTSSGASTATNSGSSTTSSGTSTATNSESSTVSSG--ASTATTSESSTTSSGASTATN 407
Query: 421 SPCSPPGTGSFS---SSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHP 477
S S +G+ + S SS+ SSG GS +S+G +++ + T +
Sbjct: 408 SESSTVSSGASTATNSESSTTSSGANTATNSGSSVTSAGSGTAALTGMHTTSHSASTAVS 467
Query: 478 DPSAGAKPCGSSSAGKIPCRSIRDILAQV 506
+ AKP GS +I ++ ++A V
Sbjct: 468 E----AKPGGSLVPWEIFLITLVSVVAAV 492
>gi|186928825 dermokine isoform 3 precursor [Homo sapiens]
Length = 416
Score = 68.9 bits (167), Expect = 1e-11
Identities = 55/158 (34%), Positives = 69/158 (43%), Gaps = 10/158 (6%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
G+ S S+ + + S GG S +S G S +Q GS+GS G+ + SS GS
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGS 272
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
S +SG S GSS SG+SG G S S SS SS SS GN +
Sbjct: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS-----GNHGGSGGGNGHK 327
Query: 184 RGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD 221
G P + S S G GQ VSSN R S +
Sbjct: 328 PGCEKPGNEARGSGESGIQGF--RGQGVSSNMREISKE 363
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/154 (31%), Positives = 67/154 (43%), Gaps = 19/154 (12%)
Query: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
M APW G+ G G P + G + P R ++ N+ C
Sbjct: 186 MNPQGAPW-GQGGNGGP----------PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
SG S S+S G S S + SSG GS+G ++ S + G S+GS G+ SSG
Sbjct: 235 SGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
Query: 121 SGSSLQGASGS-----SQLGSSSSHSGSSGSHSG 149
+ +G SGS S GSSS + G SG +G
Sbjct: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
Score = 49.3 bits (116), Expect = 9e-06
Identities = 43/123 (34%), Positives = 55/123 (44%), Gaps = 7/123 (5%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G SSG SS SGSSS GSS S GGSSG+S GS GS S+ TG S ++
Sbjct: 266 GSSSGGSS-SGSSSGGSS----GGSSGGSSGNSGGSR-GDSGSESSWGSSTGSSSGNH-G 318
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
GSG G + G+ + SG SG SS+ + G+G +
Sbjct: 319 GSGGGNGHKPGCEKPGNEARGSGESGIQGFRGQGVSSNMREISKEGNRLLGGSGDNYRNS 378
Query: 180 DNS 182
+ S
Sbjct: 379 ETS 381
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 28/170 (16%)
Query: 58 GKGDSSGFSS-----YSGSS--SSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGT 110
G+G+ G + Y G+S S G + A GG+ G + + QG A +PG
Sbjct: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA---QPGY 217
Query: 111 GYSQVSYS---------SGSGSSLQGASGSSQLG-SSSSHSGSSGSHSGSSSSHSSSSSS 160
G + S SGSG GSS G S S SGSSGS S +++ SSS
Sbjct: 218 GSVRASNQNEGCTNPPPSGSGG------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
Query: 161 FQFSSSSFQVGNGSALPTNDNS--YRGILNPSQPGQSSSSSQTFGVSSSG 208
SSS GS+ ++ NS RG SS+ S + SG
Sbjct: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSG 321
Score = 32.3 bits (72), Expect = 1.1
Identities = 92/405 (22%), Positives = 139/405 (34%), Gaps = 95/405 (23%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
CL G G++ S G S+G++I A G G + S G A G AG G S+
Sbjct: 15 CL-GSGEAGPLQS--GEESTGTNIGEALGHGLGDA-LSEGVGKAIGKEAG----GAAGSK 66
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS 174
VS + G G+ +G Q+ + + + G+ G ++ H+ ++ + + V
Sbjct: 67 VSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAA-HALGNTGHEIGRQAEDVIRHG 124
Query: 175 ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVS 234
A S++G+ PG + + +S G + +Q +P G
Sbjct: 125 ADAVR-GSWQGV-----PGHNGAWE-----TSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
H P + + S G P QG P GG G P ++G
Sbjct: 174 HG---YPGNSAGSFGMNP----------------QGAPWGQGGNGGPP---------NFG 205
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
T ++G + GY V+ S PP G S++
Sbjct: 206 -----------------TNTQGAVAQPGY----GSVRASNQNEGCTNPPPSGSGGGSSNS 244
Query: 355 PIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHP 414
G G G +GS G + SS SSS SS
Sbjct: 245 ------------------GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
Query: 415 CGSASQSPCSPPGTGSFSS--SSSSQSSGKIILQPCGSKSSSSGH 457
GS+ S S +GS SS SS+ SSG G +GH
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGN-----HGGSGGGNGH 326
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 11/122 (9%)
Query: 371 PVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGS 430
P G+GG GG +GS+ S SS S S+G + S S S G S
Sbjct: 234 PSGSGGGSSNSGGGSGSQ-----------SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
Query: 431 FSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
SS S + GS+SS S + +GG +G G + GS
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
Query: 491 AG 492
+G
Sbjct: 343 SG 344
Score = 31.2 bits (69), Expect = 2.5
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 416 GSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTG-GPDGS 474
G+ +Q + PG GS +S+Q+ G P GS SS S S +G G +G
Sbjct: 205 GTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
Query: 475 PHPDPSAGAKPCGSSSAG 492
+ S+G GSSS G
Sbjct: 263 NNNGSSSGGSSSGSSSGG 280
>gi|186928827 dermokine isoform 5 precursor [Homo sapiens]
Length = 398
Score = 67.4 bits (163), Expect = 3e-11
Identities = 54/153 (35%), Positives = 67/153 (43%), Gaps = 10/153 (6%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
G+ S S+ + + S GG S +S G S +Q GS+GS G+ + SS GS
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGS 272
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
S +SG S GSS SG+SG G S S SS SS SS GN +
Sbjct: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSS-----GNHGGSGGGNGHK 327
Query: 184 RGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQR 216
G P + S S G GQ VSSN R
Sbjct: 328 PGCEKPGNEARGSGESGIQGF--RGQGVSSNMR 358
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/154 (31%), Positives = 67/154 (43%), Gaps = 19/154 (12%)
Query: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
M APW G+ G G P + G + P R ++ N+ C
Sbjct: 186 MNPQGAPW-GQGGNGGP----------PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
SG S S+S G S S + SSG GS+G ++ S + G S+GS G+ SSG
Sbjct: 235 SGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
Query: 121 SGSSLQGASGS-----SQLGSSSSHSGSSGSHSG 149
+ +G SGS S GSSS + G SG +G
Sbjct: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNG 325
Score = 43.5 bits (101), Expect = 5e-04
Identities = 53/170 (31%), Positives = 71/170 (41%), Gaps = 28/170 (16%)
Query: 58 GKGDSSGFSS-----YSGSS--SSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGT 110
G+G+ G + Y G+S S G + A GG+ G + + QG A +PG
Sbjct: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA---QPGY 217
Query: 111 GYSQVSYS---------SGSGSSLQGASGSSQLG-SSSSHSGSSGSHSGSSSSHSSSSSS 160
G + S SGSG GSS G S S SGSSGS S +++ SSS
Sbjct: 218 GSVRASNQNEGCTNPPPSGSGG------GSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGG 271
Query: 161 FQFSSSSFQVGNGSALPTNDNS--YRGILNPSQPGQSSSSSQTFGVSSSG 208
SSS GS+ ++ NS RG SS+ S + SG
Sbjct: 272 SSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSG 321
Score = 41.6 bits (96), Expect = 0.002
Identities = 60/212 (28%), Positives = 79/212 (37%), Gaps = 39/212 (18%)
Query: 59 KGDSSGFSSYSGS--SSSGSSISSARSS-GGGSSGSSSGSSIA-----QGGSAGSFKPGT 110
+G G ++G+ +S G I ++ GG G+ G G SAGSF G
Sbjct: 129 RGSWQGVPGHNGAWETSGGHGIFGSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSF--GM 186
Query: 111 GYSQVSYSSGS-------GSSLQGASGSSQLGSSSSHSGSSG------SHSGSSSSHSSS 157
+ G G++ QGA GS + + + G S SG SS+S
Sbjct: 187 NPQGAPWGQGGNGGPPNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPPSGSGGGSSNSGG 246
Query: 158 SSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
S Q SS G+GS DN+ N S G SSS S + G S SS
Sbjct: 247 GSGSQSGSS----GSGS---NGDNN-----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSG 294
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGG 249
S S S G S +H SGG
Sbjct: 295 GSRGDSGSESSWGSSTGSSS----GNHGGSGG 322
Score = 32.3 bits (72), Expect = 1.1
Identities = 92/405 (22%), Positives = 139/405 (34%), Gaps = 95/405 (23%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
CL G G++ S G S+G++I A G G + S G A G AG G S+
Sbjct: 15 CL-GSGEAGPLQS--GEESTGTNIGEALGHGLGDA-LSEGVGKAIGKEAG----GAAGSK 66
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS 174
VS + G G+ +G Q+ + + + G+ G ++ H+ ++ + + V
Sbjct: 67 VSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAA-HALGNTGHEIGRQAEDVIRHG 124
Query: 175 ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVS 234
A S++G+ PG + + +S G + +Q +P G
Sbjct: 125 ADAVR-GSWQGV-----PGHNGAWE-----TSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
H P + + S G P QG P GG G P ++G
Sbjct: 174 HG---YPGNSAGSFGMNP----------------QGAPWGQGGNGGPP---------NFG 205
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
T ++G + GY V+ S PP G S++
Sbjct: 206 -----------------TNTQGAVAQPGY----GSVRASNQNEGCTNPPPSGSGGGSSNS 244
Query: 355 PIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHP 414
G G G +GS G + SS SSS SS
Sbjct: 245 ------------------GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
Query: 415 CGSASQSPCSPPGTGSFSS--SSSSQSSGKIILQPCGSKSSSSGH 457
GS+ S S +GS SS SS+ SSG G +GH
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGN-----HGGSGGGNGH 326
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 11/122 (9%)
Query: 371 PVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGS 430
P G+GG GG +GS+ S SS S S+G + S S S G S
Sbjct: 234 PSGSGGGSSNSGGGSGSQ-----------SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
Query: 431 FSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
SS S + GS+SS S + +GG +G G + GS
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
Query: 491 AG 492
+G
Sbjct: 343 SG 344
Score = 31.2 bits (69), Expect = 2.5
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 416 GSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTG-GPDGS 474
G+ +Q + PG GS +S+Q+ G P GS SS S S +G G +G
Sbjct: 205 GTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
Query: 475 PHPDPSAGAKPCGSSSAG 492
+ S+G GSSS G
Sbjct: 263 NNNGSSSGGSSSGSSSGG 280
>gi|55956899 keratin 9 [Homo sapiens]
Length = 623
Score = 67.0 bits (162), Expect = 4e-11
Identities = 46/133 (34%), Positives = 55/133 (41%), Gaps = 8/133 (6%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPG-----TGY 112
G+G G G SG S GGS GS G S + GGS G + G +G
Sbjct: 486 GRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGGHSGG 545
Query: 113 SQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGN 172
S +S GSG + G SGS GS + G SGS GS SH S S S+ G
Sbjct: 546 SGGGHSGGSGGNYGGGSGSGG-GSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSY--GG 602
Query: 173 GSALPTNDNSYRG 185
G + Y G
Sbjct: 603 GEEASGSGGGYGG 615
Score = 62.4 bits (150), Expect = 1e-09
Identities = 44/119 (36%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Query: 56 LTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQV 115
L G+G S G SY S GS S GG G SGS GGS G G S
Sbjct: 475 LGGRGGSGG--SYGRGSRGGSGGSYGGGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGG 532
Query: 116 SYSSGSGSSLQGASGSSQL-GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
Y GSG G SG GS ++ G SGS GS + S S S S G+G
Sbjct: 533 GYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGSGGSHGGGSG 591
Score = 61.2 bits (147), Expect = 2e-09
Identities = 48/125 (38%), Positives = 53/125 (42%), Gaps = 14/125 (11%)
Query: 58 GKGDSSGFSSYSGS-SSSGSSISSARSSGGGSS---GSSSGSSIAQGGSAGSFKPGTGYS 113
G G G+ SGS SG S SGGGS G SG GGS G G+G
Sbjct: 499 GGGSGGGYGGGSGSRGGSGGSYGGGSGSGGGSGGGYGGGSGGG-HSGGSGGGHSGGSG-- 555
Query: 114 QVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF----QFSSSSFQ 169
+Y GSGS G SG G S S GS GSH G S S S+ + S S
Sbjct: 556 -GNYGGGSGSG--GGSGGGYGGGSGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGSGGG 612
Query: 170 VGNGS 174
G GS
Sbjct: 613 YGGGS 617
Score = 58.9 bits (141), Expect = 1e-08
Identities = 47/154 (30%), Positives = 56/154 (36%), Gaps = 10/154 (6%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
+SSG GS S R S GGS GS G GGS G + G+G G
Sbjct: 466 ESSGAGKIGLGGRGGSGGSYGRGSRGGSGGSYGG-----GGSGGGYGGGSG-----SRGG 515
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
SG S G SGS GS G HSG S S S + S G
Sbjct: 516 SGGSYGGGSGSGGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGG 575
Query: 181 NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSN 214
+ RG S G S ++ G G+ S +
Sbjct: 576 SGSRGGSGGSHGGGSGFGGESGGSYGGGEEASGS 609
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/102 (41%), Positives = 48/102 (47%), Gaps = 5/102 (4%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+G G SG Y G S G S S GGS G+ G S + GGS G + G+G S
Sbjct: 524 SGSGGGSG-GGYGGGSGGGHSGGSGGGHSGGSGGNYGGGSGSGGGSGGGYGGGSGSRGGS 582
Query: 117 YSS-GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS--SSHS 155
S G GS G SG S G SGS G + G S SSHS
Sbjct: 583 GGSHGGGSGFGGESGGSY-GGGEEASGSGGGYGGGSGKSSHS 623
Score = 46.2 bits (108), Expect = 7e-05
Identities = 48/150 (32%), Positives = 56/150 (37%), Gaps = 20/150 (13%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSA--------GSF-- 106
+G G G S SS S SS S GGG G S SS GGS+ GSF
Sbjct: 14 SGGGGGGGLGSGGSIRSSYSRFSS--SGGGGGGGRFSSSSGYGGGSSRVCGRGGGGSFGY 71
Query: 107 ----KPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSS----HSGSSGSHSGSSSSHSSSS 158
G G+S S G G +G G+S G SSS GS G + S
Sbjct: 72 SYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSSGGFGGGFGGGSGGGFGGGYGSGF 131
Query: 159 SSFQFSSSSFQVGNGSALPTNDNSYRGILN 188
F G+G L N+ S LN
Sbjct: 132 GGFGGFGGGAGGGDGGILTANEKSTMQELN 161
Score = 46.2 bits (108), Expect = 7e-05
Identities = 38/107 (35%), Positives = 45/107 (42%), Gaps = 14/107 (13%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGG---SAGSFKPGTG 111
C G G S G+S Y G S G S SS GGG G S G A GG S+G F G G
Sbjct: 61 CGRGGGGSFGYS-YGGGSGGGFSASSL---GGGFGGGSRGFGGASGGGYSSSGGFGGGFG 116
Query: 112 YSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSS 158
GSG G GS G G+ G G +++ S+
Sbjct: 117 -------GGSGGGFGGGYGSGFGGFGGFGGGAGGGDGGILTANEKST 156
Score = 42.7 bits (99), Expect = 8e-04
Identities = 38/112 (33%), Positives = 43/112 (38%), Gaps = 16/112 (14%)
Query: 76 SSISSARSSGGGSSGSSSGSSIAQ----------GGSAGSFKPGTGY----SQVSYSSGS 121
SS +RS GGG G SG SI GG G F +GY S+V G
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 122 GSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
GS G S G S+S G G G S +S SS F G G
Sbjct: 67 GSFGYSYGGGSGGGFSASSLG--GGFGGGSRGFGGASGGGYSSSGGFGGGFG 116
Score = 38.1 bits (87), Expect = 0.020
Identities = 34/112 (30%), Positives = 43/112 (38%), Gaps = 6/112 (5%)
Query: 96 SIAQGGSAGSFKPGTGYSQVSYSSGSGSSL-QGASGSSQLGSSSSHSGSSGSHSGSSSSH 154
++ +GG G G + GSG S +G+ G S G S GS G + G S S
Sbjct: 456 NLLEGGQEDFESSGAGKIGLGGRGGSGGSYGRGSRGGS--GGSYGGGGSGGGYGGGSGSR 513
Query: 155 SSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSS 206
S S+ S S G GS S G S G S S +G S
Sbjct: 514 GGSGGSYGGGSGS---GGGSGGGYGGGSGGGHSGGSGGGHSGGSGGNYGGGS 562
Score = 30.0 bits (66), Expect = 5.5
Identities = 27/78 (34%), Positives = 29/78 (37%), Gaps = 5/78 (6%)
Query: 364 SSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPC 423
SS+ + G GG L GGS S SS SSSSG G S C
Sbjct: 7 SSSYLSRSGGGGGGGLGSGGSIRSSYSRFSSSGGGGGGGRFSSSSGY-----GGGSSRVC 61
Query: 424 SPPGTGSFSSSSSSQSSG 441
G GSF S S G
Sbjct: 62 GRGGGGSFGYSYGGGSGG 79
Score = 30.0 bits (66), Expect = 5.5
Identities = 33/102 (32%), Positives = 39/102 (38%), Gaps = 3/102 (2%)
Query: 113 SQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGN 172
S +S S G G G+ GS + SS S SSG G SSS S + G
Sbjct: 9 SYLSRSGGGGGGGLGSGGS--IRSSYSRFSSSGGGGGGGRFSSSSGYGGGSSRVCGRGGG 66
Query: 173 GS-ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSS 213
GS S G S G S+ FG +S G SS
Sbjct: 67 GSFGYSYGGGSGGGFSASSLGGGFGGGSRGFGGASGGGYSSS 108
>gi|153791670 keratin 76 [Homo sapiens]
Length = 638
Score = 65.1 bits (157), Expect = 2e-10
Identities = 51/117 (43%), Positives = 60/117 (51%), Gaps = 10/117 (8%)
Query: 63 SGFSSYSGSSSSGSSIS---SARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
S +S SGSS S + S SGG GSSS SS G S GS G+GY VS S
Sbjct: 510 SNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGS---GSGYGGVSSGS 566
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFS-SSSFQVGNGSA 175
G +G+SGS Q SS S G +GS S S S SSS S Q S S ++ G G +
Sbjct: 567 TGG---RGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGS 620
Score = 59.3 bits (142), Expect = 8e-09
Identities = 53/133 (39%), Positives = 63/133 (47%), Gaps = 15/133 (11%)
Query: 71 SSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASG 130
+S+SGSS S+R GG SGS SG +GGS+ S G G S GSGS G S
Sbjct: 513 TSTSGSS-GSSRGVFGGVSGSGSGG--YKGGSSSSSSSGYG-----VSGGSGSGYGGVSS 564
Query: 131 SSQLGSSSS---HSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGIL 187
S G SS S SSGS G + S S S S SS S Q GS + I
Sbjct: 565 GSTGGRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSI- 623
Query: 188 NPSQPGQSSSSSQ 200
+ Q++SSSQ
Sbjct: 624 ---RFSQTTSSSQ 633
Score = 52.8 bits (125), Expect = 8e-07
Identities = 44/128 (34%), Positives = 55/128 (42%), Gaps = 8/128 (6%)
Query: 46 TRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGS 105
+ +TS + + +G G S G S SS+ S G S GS SG GS G
Sbjct: 510 SNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTG- 568
Query: 106 FKPGTGYSQVSYSSGSGSSLQGAS----GSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF 161
G G S SS SGS L GA S +GSSS +SG S S+S F
Sbjct: 569 ---GRGSSGSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRF 625
Query: 162 QFSSSSFQ 169
++SS Q
Sbjct: 626 SQTTSSSQ 633
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/114 (36%), Positives = 54/114 (47%), Gaps = 12/114 (10%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+G G G SS S SS G S S GG SSGS+ G GS+GS++ + S++
Sbjct: 532 SGSGGYKGGSSSSSSSGYGVSGGSGSGYGGVSSGSTGGR-----GSSGSYQSSSSGSRL- 585
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSS----HSSSSSSFQFSSS 166
G+GS SG S SG SG SG S S ++SS Q SS+
Sbjct: 586 --GGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQHSST 637
Score = 40.0 bits (92), Expect = 0.005
Identities = 43/138 (31%), Positives = 55/138 (39%), Gaps = 43/138 (31%)
Query: 77 SISSARSSGGGSSGSSSGSSIAQGGS-AGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLG 135
S+ S +S GSSGSS G GS +G +K G+ S SS SG + G SGS G
Sbjct: 507 SVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGS-----SSSSSSGYGVSGGSGSGYGG 561
Query: 136 SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQS 195
SS +G GS S S+Q SSS ++G ++
Sbjct: 562 VSSGSTGGRGS-----------SGSYQSSSSGSRLGGAGSI------------------- 591
Query: 196 SSSSQTFGVSSSGQSVSS 213
VS SG SS
Sbjct: 592 -------SVSHSGMGSSS 602
Score = 38.5 bits (88), Expect = 0.015
Identities = 30/90 (33%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G S GFS S S S +S SGG G+ S AGSF + Y+ S S
Sbjct: 12 GRSQGFSGRSAVVSGSSRMSCVARSGGAGGGACGFRS-----GAGSFGSRSLYNLGSNKS 66
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
S S G+S + G S G +G + G
Sbjct: 67 ISISVAAGSSRAGGFGGGRSSCGFAGGYGG 96
Score = 34.7 bits (78), Expect = 0.22
Identities = 43/131 (32%), Positives = 54/131 (41%), Gaps = 28/131 (21%)
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSS------SFQFSSSSFQVGNGSALPTN 179
Q A S + + +S SGSSGS G S S S S SSS + V GS
Sbjct: 501 QSAVCISVVSNVTSTSGSSGSSRGVFGGVSGSGSGGYKGGSSSSSSSGYGVSGGSG---- 556
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPY 239
+ Y G+ + S G+ SS S + SSSG + +G VSHSG
Sbjct: 557 -SGYGGVSSGSTGGRGSSGS--YQSSSSGSRLGG--------------AGSISVSHSGMG 599
Query: 240 IPS-SHSVSGG 249
S S SGG
Sbjct: 600 SSSGSIQTSGG 610
Score = 32.7 bits (73), Expect = 0.84
Identities = 43/122 (35%), Positives = 51/122 (41%), Gaps = 20/122 (16%)
Query: 353 SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPY 412
SN S S+ SS F GGV G GS G K SSS S +S SG Y
Sbjct: 510 SNVTSTSGSSGSSRGVF-----GGVS--GSGSGGYK---GGSSSSSSSGYGVSGGSGSGY 559
Query: 413 HPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTL-TGGP 471
G +S S +GS+ SSSS G G+ S S H M SS ++ T G
Sbjct: 560 G--GVSSGSTGGRGSSGSYQSSSSGSRLG-------GAGSISVSHSGMGSSSGSIQTSGG 610
Query: 472 DG 473
G
Sbjct: 611 SG 612
Score = 32.0 bits (71), Expect = 1.4
Identities = 32/100 (32%), Positives = 40/100 (40%), Gaps = 12/100 (12%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSIS----SARSSGGGSSGSSSGSSIAQGGS-AGSFKPGTG 111
+G G S Y+ S+ SIS S+R+ G G SS G + GG GS+ G G
Sbjct: 48 SGAGSFGSRSLYNLGSNKSISISVAAGSSRAGGFGGGRSSCGFAGGYGGGFGGSYGGGFG 107
Query: 112 YSQVSYSSGSGSSLQGASGSSQLGSSSSHS--GSSGSHSG 149
+ G GS GA G G G GS G
Sbjct: 108 GGR-----GVGSGFGGAGGFGGAGGFGGPGVFGGPGSFGG 142
Score = 32.0 bits (71), Expect = 1.4
Identities = 36/124 (29%), Positives = 49/124 (39%), Gaps = 8/124 (6%)
Query: 288 SVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISE 347
S S G + V GS G + S GY G GV S + G S
Sbjct: 518 SSGSSRGVFGGVSGSGSGGYKGGSSSSSSS----GYGVSGGSGSGYGGVSSGSTGGRGSS 573
Query: 348 GKYFSSNPIIPSQSAASSAIAFQPVG--TGGVQLCGGG--STGSKGPCSPSSSRVPSSSS 403
G Y SS+ A S +++ +G +G +Q GG +G G S S+ SSS
Sbjct: 574 GSYQSSSSGSRLGGAGSISVSHSGMGSSSGSIQTSGGSGYKSGGGGSTSIRFSQTTSSSQ 633
Query: 404 ISSS 407
SS+
Sbjct: 634 HSST 637
>gi|40068466 AT rich interactive domain 1B (SWI1-like) isoform 1
[Homo sapiens]
Length = 2231
Score = 65.1 bits (157), Expect = 2e-10
Identities = 119/488 (24%), Positives = 172/488 (35%), Gaps = 85/488 (17%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGG------SSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G Y GSS+ +SS R GGG G++S S A G +AG F+ G +Q +
Sbjct: 296 GGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ--H 353
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS------SSHSSSSSSFQFSSSSFQVG 171
SG+ +L +S S+ GS +S S S S +++ ++ Q
Sbjct: 354 PSGATPTLNQLL-TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ----------RPCSSD 221
G L + + +P+ S + G ++ +Q RP
Sbjct: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
Query: 222 IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGK 281
+ +P S S PY S+ G QR + + + PG + G P +
Sbjct: 473 MGSNPHSQP---QQSSPYPGGSYGPPGPQRYPIGIQGR----TPGAMAGMQ-----YPQQ 520
Query: 282 PCPPITSVDKSYGGYEVVG----GSSDSY--------LVPGMTY----SKGKIYPVGYFT 325
PP YG V G G Y L P Y S+ + P +
Sbjct: 521 QMPP------QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 326 KENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGV---QLCGG 382
+E G+ P A G P E S S +I P GT +
Sbjct: 575 QEG--YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSAS 632
Query: 383 GSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGK 442
GST S+G S + S + S +P P S SP + S S +S +
Sbjct: 633 GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ 692
Query: 443 IILQPCGSKSSSSGHPCMSVSSLT-----LTG---------------GPDGSPHPDPSAG 482
+ QP GS+S SS HP +S S + + G GP SPHP P G
Sbjct: 693 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSP-GG 751
Query: 483 AKPCGSSS 490
G SS
Sbjct: 752 QMHAGISS 759
Score = 52.8 bits (125), Expect = 8e-07
Identities = 116/453 (25%), Positives = 166/453 (36%), Gaps = 83/453 (18%)
Query: 54 PCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYS 113
P L+G D + + SS+ S+ S S G S+ + S S S G S
Sbjct: 608 PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS 667
Query: 114 QVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
V GS S G + + S GS S SSSH + S S F G
Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS-ESSSHPALSQSPMPQERGFMAG-- 724
Query: 174 SALPTNDNSYRGILNPSQPG--------------------QSSSSSQTFG--VSSSGQSV 211
T N P Q G Q S+SS T+G +S G
Sbjct: 725 ----TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
Query: 212 SSNQRPCSSDIPDSPCSG-GPIVSHS--------GPYIPSSHSVSGGQRPVVVVVDQH-- 260
+ ++ P S +P + SG GP + S GP P +V G+ P + ++
Sbjct: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHGQGPSQPCG-AVPLGRMPSAGMQNRPFP 839
Query: 261 GSGAPGVVQGPPCSNGGLPGKPCPPITSVDK-----SYGGYEVVGGSSDSYL--VPGMTY 313
G+ + P S G PG PP+ +V++ + + S+ S PGM
Sbjct: 840 GNMSSMTPSSPGMSQQGGPGMG-PPMPTVNRKAQEAAAAVMQAAANSAQSRQGSFPGMNQ 898
Query: 314 SKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAF---- 369
S Y P+ S + + A P +S P + + SAAS +A
Sbjct: 899 SGLMASSSPY---SQPMNNSSSLMNTQAPP-------YSMAPAMVNSSAASVGLADMMSP 948
Query: 370 -------------QPVGTGGVQLCGGGSTGSKG---PCSPSSSRVPSSSSISSSSGLPYH 413
+ GT + S S+G P +P + VPS S SS+S +H
Sbjct: 949 GESKLPLPLKADGKEEGTPQPESKSKDSYSSQGISQPPTPGNLPVPSPMSPSSASISSFH 1008
Query: 414 PCGSASQSPCSP--PGTGSFSSSSSSQSSGKII 444
G S S SP P T S SSSS ++G+ I
Sbjct: 1009 --GDESDSISSPGWPKTPSSPKSSSSTTTGEKI 1039
Score = 31.2 bits (69), Expect = 2.5
Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 21/132 (15%)
Query: 143 SSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF 202
+SGS G + S+ S+S +V PT ++ G + P Q G+SS T
Sbjct: 1167 NSGSLQGPQTPQSTGSNSMA------EVPGDLKPPTPASTPHGQMTPMQGGRSS----TI 1216
Query: 203 GVSSSGQSVSSNQRP-CSSDIPDSPCSGG---PIVSHSGPYIPSSHSVSGGQRPVVVVVD 258
V VS + P +S P++P G P V PY P+ GG R V
Sbjct: 1217 SVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPF-GGMRKV----- 1270
Query: 259 QHGSGAPGVVQG 270
GS P + QG
Sbjct: 1271 -PGSSEPFMTQG 1281
>gi|40068462 AT rich interactive domain 1B (SWI1-like) isoform 3
[Homo sapiens]
Length = 2178
Score = 65.1 bits (157), Expect = 2e-10
Identities = 119/488 (24%), Positives = 172/488 (35%), Gaps = 85/488 (17%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGG------SSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G Y GSS+ +SS R GGG G++S S A G +AG F+ G +Q +
Sbjct: 296 GGGGYGGSSAGYGVLSSPRQQGGGMMMGPGGGGAASLSKAAAGSAAGGFQRFAGQNQ--H 353
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS------SSHSSSSSSFQFSSSSFQVG 171
SG+ +L +S S+ GS +S S S S +++ ++ Q
Sbjct: 354 PSGATPTLNQLL-TSPSPMMRSYGGSYPEYSSPSAPPPPPSQPQSQAAAAGAAAGGQQAA 412
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ----------RPCSSD 221
G L + + +P+ S + G ++ +Q RP
Sbjct: 413 AGMGLGKDMGAQYAAASPAWAAAQQRSHPAMSPGTPGPTMGRSQGSPMDPMVMKRPQLYG 472
Query: 222 IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGK 281
+ +P S S PY S+ G QR + + + PG + G P +
Sbjct: 473 MGSNPHSQP---QQSSPYPGGSYGPPGPQRYPIGIQGR----TPGAMAGMQ-----YPQQ 520
Query: 282 PCPPITSVDKSYGGYEVVG----GSSDSY--------LVPGMTY----SKGKIYPVGYFT 325
PP YG V G G Y L P Y S+ + P +
Sbjct: 521 QMPP------QYGQQGVSGYCQQGQQPYYSQQPQPPHLPPQAQYLPSQSQQRYQPQQDMS 574
Query: 326 KENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGV---QLCGG 382
+E G+ P A G P E S S +I P GT +
Sbjct: 575 QEG--YGTRSQPPLAPGKPNHEDLNLIQQERPSSLPDLSGSIDDLPTGTEATLSSAVSAS 632
Query: 383 GSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGK 442
GST S+G S + S + S +P P S SP + S S +S +
Sbjct: 633 GSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPSPVGSPVGSNQSRSGPISPASIPGSQ 692
Query: 443 IILQPCGSKSSSSGHPCMSVSSLT-----LTG---------------GPDGSPHPDPSAG 482
+ QP GS+S SS HP +S S + + G GP SPHP P G
Sbjct: 693 MPPQPPGSQSESSSHPALSQSPMPQERGFMAGTQRNPQMAQYGPQQTGPSMSPHPSP-GG 751
Query: 483 AKPCGSSS 490
G SS
Sbjct: 752 QMHAGISS 759
Score = 47.0 bits (110), Expect = 4e-05
Identities = 93/391 (23%), Positives = 132/391 (33%), Gaps = 52/391 (13%)
Query: 54 PCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYS 113
P L+G D + + SS+ S+ S S G S+ + S S S G S
Sbjct: 608 PDLSGSIDDLPTGTEATLSSAVSASGSTSSQGDQSNPAQSPFSPHASPHLSSIPGGPSPS 667
Query: 114 QVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
V GS S G + + S GS S SSSH + S S F G
Sbjct: 668 PVGSPVGSNQSRSGPISPASIPGSQMPPQPPGSQS-ESSSHPALSQSPMPQERGFMAG-- 724
Query: 174 SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIV 233
T N P Q G S S + G S Q S GP
Sbjct: 725 ----TQRNPQMAQYGPQQTGPSMSPHPSPGGQMHAGISSFQQSNSSGTYGPQMSQYGPQG 780
Query: 234 SHSGPY----IPS-SHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITS 288
++S P +PS S+S G + HG QGP G +P P
Sbjct: 781 NYSRPPAYSGVPSASYSGPGPGMGISANNQMHG-------QGPSQPCGAVPLGRMPSAGM 833
Query: 289 VDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPI-SE 347
++ + G SS + PGM+ +G PG+ GPP+ +
Sbjct: 834 QNRPFPG----NMSSMTPSSPGMSQ-----------------QGGPGM-----GPPMPTV 867
Query: 348 GKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSS 407
+ Q+AA+SA + Q G +G SP S + +SSS+ ++
Sbjct: 868 NRKAQEAAAAVMQAAANSAQSRQG------SFPGMNQSGLMASSSPYSQPMNNSSSLMNT 921
Query: 408 SGLPYHPCGSASQSPCSPPGTGSFSSSSSSQ 438
PY + S + G S S+
Sbjct: 922 QAPPYSMAPAMVNSSAASVGLADMMSPGESK 952
Score = 31.2 bits (69), Expect = 2.5
Identities = 39/132 (29%), Positives = 54/132 (40%), Gaps = 21/132 (15%)
Query: 143 SSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF 202
+SGS G + S+ S+S +V PT ++ G + P Q G+SS T
Sbjct: 1114 NSGSLQGPQTPQSTGSNSMA------EVPGDLKPPTPASTPHGQMTPMQGGRSS----TI 1163
Query: 203 GVSSSGQSVSSNQRP-CSSDIPDSPCSGG---PIVSHSGPYIPSSHSVSGGQRPVVVVVD 258
V VS + P +S P++P G P V PY P+ GG R V
Sbjct: 1164 SVHDPFSDVSDSSFPKRNSMTPNAPYQQGMSMPDVMGRMPYEPNKDPF-GGMRKV----- 1217
Query: 259 QHGSGAPGVVQG 270
GS P + QG
Sbjct: 1218 -PGSSEPFMTQG 1228
>gi|195972866 keratin 10 [Homo sapiens]
Length = 584
Score = 64.7 bits (156), Expect = 2e-10
Identities = 47/128 (36%), Positives = 54/128 (42%), Gaps = 9/128 (7%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G+G S Y G SS G S SGGG G GSS GG G G G S Y
Sbjct: 463 GRGGGSFGGGYGGGSSGGGS------SGGGHGGGHGGSS---GGGYGGGSSGGGSSGGGY 513
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
GS S G S S G SS G G GSS SSS + SSS + S+
Sbjct: 514 GGGSSSGGHGGSSSGGYGGGSSGGGGGGYGGGSSGGGSSSGGGYGGGSSSGGHKSSSSGS 573
Query: 178 TNDNSYRG 185
++S +G
Sbjct: 574 VGESSSKG 581
Score = 57.0 bits (136), Expect = 4e-08
Identities = 49/142 (34%), Positives = 56/142 (39%), Gaps = 13/142 (9%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSL 125
S G SSG S GGG G SSG + GG G +G SSG GSS
Sbjct: 451 SLLEGEGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSG 510
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRG 185
G G S SSG H GSSS SS + G+ ++ Y G
Sbjct: 511 GGYGGGS----------SSGGHGGSSSGGYGGGSS-GGGGGGYGGGSSGGGSSSGGGYGG 559
Query: 186 ILNPSQPGQSSSSSQTFGVSSS 207
S G SSSS + G SSS
Sbjct: 560 --GSSSGGHKSSSSGSVGESSS 579
Score = 53.9 bits (128), Expect = 4e-07
Identities = 41/104 (39%), Positives = 43/104 (41%), Gaps = 9/104 (8%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G G SSG Y G SS G S S GG SSG GSS G S G GY
Sbjct: 490 GHGGSSG-GGYGGGSSGGGS-SGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGY----- 542
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF 161
G GSS G+S G SS G S SGS SS +
Sbjct: 543 --GGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESSSKGPRY 584
Score = 52.8 bits (125), Expect = 8e-07
Identities = 43/113 (38%), Positives = 48/113 (42%), Gaps = 12/113 (10%)
Query: 68 YSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQG 127
YS S SS S GGG G SS+ S GS G G+S +S GS S +G
Sbjct: 5 YSSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSL--GGGFSSGGFSGGSFS--RG 60
Query: 128 ASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF------QFSSSSFQVGNGS 174
+SG G SS G G G S S SSSF F SF G GS
Sbjct: 61 SSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSF--GGGS 111
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/96 (39%), Positives = 40/96 (41%), Gaps = 4/96 (4%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG--SSIAQGGSAGSFKPGTGYSQ 114
+G G G SG G S S GG GSSSG + GG G G G
Sbjct: 483 SGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGGGSSSGGHGGSSSGGYGGGSSGGGGGGY 542
Query: 115 VSYSSGSGSSLQG--ASGSSQLGSSSSHSGSSGSHS 148
SSG GSS G GSS G SS SGS G S
Sbjct: 543 GGGSSGGGSSSGGGYGGGSSSGGHKSSSSGSVGESS 578
Score = 49.7 bits (117), Expect = 7e-06
Identities = 33/94 (35%), Positives = 38/94 (40%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G G G G SS S S GG SSG SG S ++G S G G+
Sbjct: 18 GGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGL 77
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS 151
G S +G+ GSS G S S GS G S
Sbjct: 78 GGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGS 111
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/94 (38%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Query: 58 GKGDSSGFSSYSGSSSSGS---SISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
G G G SS SSS GS SS SGG S SSG GGS+G + G+
Sbjct: 24 GCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGGCF-GGSSGGYGGLGGFGG 82
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS 148
S+ GSS G S G S GS G S
Sbjct: 83 GSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGS 116
Score = 41.6 bits (96), Expect = 0.002
Identities = 31/89 (34%), Positives = 35/89 (39%), Gaps = 8/89 (8%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+ KG G +S SG S S S GG GSS G G GSF+ G
Sbjct: 38 SSKGSLGG--GFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYG----- 90
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSG 145
SS G S G+ G G S GS G
Sbjct: 91 -SSSFGGSYGGSFGGGSFGGGSFGGGSFG 118
Score = 34.7 bits (78), Expect = 0.22
Identities = 38/123 (30%), Positives = 45/123 (36%), Gaps = 8/123 (6%)
Query: 89 SGSSSGSSIAQG--GSAGSFKPGTGYSQVSYSSGSGSSLQG-ASGSSQLGSSSSHSGSSG 145
S S SS G G G G G S + SS GS G +SG GS S S G
Sbjct: 6 SSSKHYSSSRSGGGGGGGGCGGGGGVSSLRISSSKGSLGGGFSSGGFSGGSFSRGSSGGG 65
Query: 146 SHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVS 205
GSS + F SF+ GS+ + SY G G S +FG
Sbjct: 66 CFGGSSGGYGGLGG---FGGGSFRGSYGSS--SFGGSYGGSFGGGSFGGGSFGGGSFGGG 120
Query: 206 SSG 208
G
Sbjct: 121 GFG 123
Score = 34.7 bits (78), Expect = 0.22
Identities = 26/83 (31%), Positives = 31/83 (37%), Gaps = 2/83 (2%)
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRG 185
+G+SG G S G G SG SS SS G S ++ Y G
Sbjct: 456 EGSSGGGGRGGGSFGGGYGGGSSGGGSSGGGHGGGHGGSSGGGYGGGSSGGGSSGGGYGG 515
Query: 186 ILNPSQPGQSSSSSQTFGVSSSG 208
S G SSS +G SSG
Sbjct: 516 --GSSSGGHGGSSSGGYGGGSSG 536
Score = 34.3 bits (77), Expect = 0.29
Identities = 25/73 (34%), Positives = 28/73 (38%), Gaps = 3/73 (4%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGS--AGSFKPGTGYSQVSY 117
G S G+ G S SS GGS G S G GGS GSF G G+ +
Sbjct: 69 GSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSFGGGSFGGGSFGGGSF-GGGGFGGGGF 127
Query: 118 SSGSGSSLQGASG 130
G G G G
Sbjct: 128 GGGFGGGFGGDGG 140
Score = 33.5 bits (75), Expect = 0.49
Identities = 34/103 (33%), Positives = 38/103 (36%), Gaps = 17/103 (16%)
Query: 56 LTGKGDSSGFS--SYSGSSSSGSSISSARSSGGGSSGSSSGS------SIAQGGS-AGSF 106
L G S GFS S+S SS G + GG G GS S + GGS GSF
Sbjct: 43 LGGGFSSGGFSGGSFSRGSSGGGCFGGSSGGYGGLGGFGGGSFRGSYGSSSFGGSYGGSF 102
Query: 107 KPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
G S G GS G+ G G G G G
Sbjct: 103 GGG--------SFGGGSFGGGSFGGGGFGGGGFGGGFGGGFGG 137
Score = 29.6 bits (65), Expect = 7.1
Identities = 25/70 (35%), Positives = 25/70 (35%), Gaps = 12/70 (17%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G SS F G S G S S GGGS G G GG G F G G
Sbjct: 87 GSYGSSSFGGSYGGSFGGGSFGGG-SFGGGSFG---GGGFGGGGFGGGFGGGFG------ 136
Query: 118 SSGSGSSLQG 127
G G L G
Sbjct: 137 --GDGGLLSG 144
>gi|239743293 PREDICTED: mucin 12 [Homo sapiens]
Length = 5478
Score = 64.3 bits (155), Expect = 3e-10
Identities = 99/412 (24%), Positives = 158/412 (38%), Gaps = 38/412 (9%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
+S+ F S SGS+ G+ +S ARS+ G G S+ S ++ + + PG+ S
Sbjct: 4023 ESTTFPSSSGST--GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS--PTTPSLSE 4078
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG-SALPTN 179
++ + S S + + SSG SS+SHS S+ + +G S PT
Sbjct: 4079 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTT 4138
Query: 180 DNSYRGILNPS-QPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIVSH 235
+S +G + PG +++S S QS + + P ++ +PD + G +V
Sbjct: 4139 SHSSQGSTEATLSPGSTTAS------SLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEA 4191
Query: 236 SGPYIPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPGKPCPPITSVDKS 292
S P +HS +G + +G Q P S+ P P V+ S
Sbjct: 4192 STP----THSSTGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVS 4247
Query: 293 YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFS 352
+ + ++ T +G + V SPG A P S
Sbjct: 4248 TTYHSRPSSTPTTHFSASST-------TLGRSEESTTVHSSPGATGTALFPTRSATSVLV 4300
Query: 353 SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVP---SSSSISSSSG 409
P S+ S+ P T L +T P SP ++ P +SS +S S
Sbjct: 4301 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 4360
Query: 410 LPYHPCGS----ASQSPCSPPGTGSFSSSS-SSQSSGKIILQPCGSKSSSSG 456
+ GS A S + PG S++S SS S L P + +SS G
Sbjct: 4361 TSHSRPGSMHTTAFPSSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 4412
Score = 62.4 bits (150), Expect = 1e-09
Identities = 104/427 (24%), Positives = 164/427 (38%), Gaps = 43/427 (10%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
+S+ F S SGS+ G+++S ARS+ G G S+ S ++ + + PG+ S
Sbjct: 2940 ESTTFPSSSGST--GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS--PTTPSLSE 2995
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG-SALPTN 179
++ + S S + + SSG SS+SHS S+ + +G S PT
Sbjct: 2996 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTA 3055
Query: 180 DNSYRGILNPS-QPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIVSH 235
+S +G + PG +++S S QS + + P ++ +PD + G +V
Sbjct: 3056 SHSSQGSTEATLSPGSTTAS------SLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEA 3108
Query: 236 SGPYIPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPGKPCPPITSVDKS 292
S P +HS +G + +G Q P S+ P P V+ S
Sbjct: 3109 STP----THSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVS 3164
Query: 293 YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFS 352
+ + ++ T +G + V SPG A P S
Sbjct: 3165 TTYHSRPSSTPTTHFSASST-------TLGRSEESTTVHSSPGATGTALFPTRSATSVLV 3217
Query: 353 SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVP---SSSSISSSSG 409
P S+ S+ P T L +T P SP ++ P +SS +S S
Sbjct: 3218 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 3277
Query: 410 LPYHPCGS----ASQSPCSPPGTGSFSSSS-SSQSSGKIILQPCGSKSSSSGHPCMSVSS 464
+ GS A + PG S++S SS S L P GS ++SS P S
Sbjct: 3278 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSP-GSTTASSLGP----ES 3332
Query: 465 LTLTGGP 471
T GP
Sbjct: 3333 TTFHSGP 3339
Score = 61.2 bits (147), Expect = 2e-09
Identities = 98/412 (23%), Positives = 157/412 (38%), Gaps = 38/412 (9%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
+S+ F S SGS+ G+ +S ARS+ G G S+ S ++ + + PG+ S
Sbjct: 1383 ESTTFPSSSGST--GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS--PTTPSLSE 1438
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFS-SSSFQVGNGSALPTN 179
++ + S S + + SSG SS+SHS S+ + S + S PT
Sbjct: 1439 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT 1498
Query: 180 DNSYRGILNPS-QPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIVSH 235
+S +G + PG +++S S QS + + P ++ +PD + G +V
Sbjct: 1499 SHSSQGSTEATLSPGSTTAS------SLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEA 1551
Query: 236 SGPYIPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPGKPCPPITSVDKS 292
S P +HS +G + +G Q P S+ P P V+ S
Sbjct: 1552 STP----THSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVS 1607
Query: 293 YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFS 352
+ + ++ T +G + V SPG A P S
Sbjct: 1608 TTYHSRPSSTPTTHFSASST-------TLGRSEESTTVHSSPGATGTALFPTRSATSVLV 1660
Query: 353 SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVP---SSSSISSSSG 409
P S+ S+ P T L +T P SP ++ P +SS +S S
Sbjct: 1661 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1720
Query: 410 LPYHPCGS----ASQSPCSPPGTGSFSSSS-SSQSSGKIILQPCGSKSSSSG 456
+ GS A + PG S++S SS S L P + +SS G
Sbjct: 1721 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 1772
Score = 56.6 bits (135), Expect = 5e-08
Identities = 95/418 (22%), Positives = 159/418 (38%), Gaps = 54/418 (12%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPG-------TGYS 113
+S+ F S SGS+ G+++S ARS+ G G S+ S ++ + + PG + S
Sbjct: 2466 ESTTFPSSSGST--GTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLSEKS 2523
Query: 114 QVSYSS--------------GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSS 159
Y+S SG S + ++ SQ GS+ + + + + S HS++S
Sbjct: 2524 TTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSH 2583
Query: 160 SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSS---SSSQTFGVSSSGQSVSSNQR 216
S S+ + + ++ T+ S + S PG + S T +S +S + +
Sbjct: 2584 SSPGSTDTTLL--PASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSS 2641
Query: 217 PCSSD---IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG---VVQG 270
P S+ PDS S G + + + HS +G R + G G Q
Sbjct: 2642 PGSTHTTLFPDSTTSSGIVEAST-----RVHSSTGSPRTTLSPASSTSPGLQGESTTFQT 2696
Query: 271 PPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPV 330
P S P P V++S Y GS+ + P + + G F
Sbjct: 2697 HPASTHTTPSPPSTATAPVEES-TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDA 2755
Query: 331 KGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP 390
G+ PS A G+ +S S S+ I P T L +T P
Sbjct: 2756 SGT--TPSSAHSTTSGRGESTTSR-----ISPGSTEITTLPGSTTTPGLSEASTTFYSSP 2808
Query: 391 CSPSSSRVPSS-------SSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
SP+++ P+S ++S P + S + + PG S++ S S G
Sbjct: 2809 RSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 2866
Score = 55.1 bits (131), Expect = 2e-07
Identities = 102/458 (22%), Positives = 170/458 (37%), Gaps = 61/458 (13%)
Query: 30 TLAKSIGTFSDPCKDPTRI-TSPNDPCLTGKGDSSGFS--------SYSGSSSSGSSISS 80
T++ T S ++PT +SP T DSS S S+S ++G+ +
Sbjct: 1950 TISSPPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 2009
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGT----GYSQVS-----------------YSS 119
ARS+ G S+ S I+ G + PG+ G S+ S ++
Sbjct: 2010 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 2069
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
SG S + + S+ GS+ + + + + S HS++S S S+ + + ++ T+
Sbjct: 2070 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL--PASTTTS 2127
Query: 180 DNSYRGILNPSQPGQSS---SSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIV 233
S + S PG + S T +S +S + + P S+ PDS S G +
Sbjct: 2128 GPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 2187
Query: 234 SHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG---VVQGPPCSNGGLPGKPCPPITSVD 290
+ + HS +G R + G G Q P S P P V+
Sbjct: 2188 AST-----RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 2242
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
+S Y GS+ + P + + G F G+ PS A G+
Sbjct: 2243 ES-TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT--TPSSAHSTTSGRGES 2299
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS-------SS 403
+S S S+ I P T L +T P SP+++ P+S
Sbjct: 2300 TTSR-----ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 2354
Query: 404 ISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
++S P + S + + PG S++ S S G
Sbjct: 2355 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 2392
Score = 53.9 bits (128), Expect = 4e-07
Identities = 101/458 (22%), Positives = 171/458 (37%), Gaps = 61/458 (13%)
Query: 30 TLAKSIGTFSDPCKDPTRI-TSPNDPCLTGKGDSSGFS--------SYSGSSSSGSSISS 80
T++ + T S ++PT +SP T DSS S S+S ++G+ +
Sbjct: 3507 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 3566
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGT----GYSQVS-----------------YSS 119
ARS+ G S+ S I+ G + PG+ G S+ S ++
Sbjct: 3567 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPASTT 3626
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
SG S + + S+ GS+ + + + + S HS++S S S+ + + ++ T+
Sbjct: 3627 SSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL--PASTTTS 3684
Query: 180 DNSYRGILNPSQPGQSS---SSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIV 233
+S + S G + S T +S +S + + P S+ PDS S G +
Sbjct: 3685 GSSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTSSGIVE 3744
Query: 234 SHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG---VVQGPPCSNGGLPGKPCPPITSVD 290
+ + HS +G R + G G Q P S P P V+
Sbjct: 3745 AST-----RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 3799
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
+S Y GS+ + P + + G F G+ PS A G+
Sbjct: 3800 ES-TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT--TPSSAHSTTSGRGES 3856
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS-------SS 403
+S S S+ I P T L +T P SP+++ P+S
Sbjct: 3857 TTSR-----ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 3911
Query: 404 ISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
++S P + S + + PG S++ S S G
Sbjct: 3912 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSPG 3949
Score = 53.5 bits (127), Expect = 5e-07
Identities = 105/475 (22%), Positives = 179/475 (37%), Gaps = 63/475 (13%)
Query: 30 TLAKSIGTFSDPCKDPTRI-TSPNDPCLTGKGDSSGFS--------SYSGSSSSGSSISS 80
T++ + T S ++PT +SP T DSS S S+S ++G+ +
Sbjct: 867 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 926
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGT----GYSQVS-----------------YSS 119
ARS+ G S+ S I+ G + PG+ G S+ S ++
Sbjct: 927 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 986
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
SG S + + S+ GS+ + + + + S HS++S S S+ + + ++ T+
Sbjct: 987 SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL--PASTTTS 1044
Query: 180 DNSYRGILNPSQPGQSS---SSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIV 233
S + S G + S T +S +S + + P S+ PDS S G +
Sbjct: 1045 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 1104
Query: 234 SHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG---VVQGPPCSNGGLPGKPCPPITSVD 290
+ + HS +G R + G G Q P S P P V+
Sbjct: 1105 AST-----RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 1159
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
+S Y GS+ + P + + G F G+ PS A G+
Sbjct: 1160 ES-TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT--TPSSAHSTTSGRGES 1216
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS-------SS 403
+S S S+ I P T L +T P SP+++ P+S
Sbjct: 1217 TTSR-----ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 1271
Query: 404 ISSSSGLPYHPCGSASQSPCSPPGTGSFSSS--SSSQSSGKIILQPCGSKSSSSG 456
++S P + S + + PG S++ SSS+ S + + P + +S G
Sbjct: 1272 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHG 1326
Score = 52.8 bits (125), Expect = 8e-07
Identities = 105/504 (20%), Positives = 184/504 (36%), Gaps = 62/504 (12%)
Query: 26 LLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSS-----YSGSSSSGSSISS 80
L P A S+ +P P S L G ++G S YS S +++S
Sbjct: 3206 LFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 3264
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSH 140
A ++ G S S+ S G + + PG+ +++ G S S ++SH
Sbjct: 3265 ASTTSSGVSEESTTSHSRPGSTHTTAFPGS------------TTMPGVSQES----TASH 3308
Query: 141 SGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA----LPTNDNSYRGILNPSQPGQSS 196
S S GS + S S+++SS S++F G GS LP N + G+L S P SS
Sbjct: 3309 S-SPGSTDTTLSPGSTTASSLGPESTTFHSGPGSTETTLLPDNTTA-SGLLEASTPVHSS 3366
Query: 197 SSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVV 256
+ S +S +G + + P+S + + + ++ S + G
Sbjct: 3367 TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 3426
Query: 257 VDQHGSGAPG------VVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP- 309
S G V P + P + + + Y GS+ + P
Sbjct: 3427 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 3486
Query: 310 -GMTYSKGKIYPVGYFTKENPVKGSPGV--------PSFAAGPPISEGKYFSSNPIIPSQ 360
T +G+ + + + + +P S+ + P + +F + +
Sbjct: 3487 SDTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 3546
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTG---SKGPCSPSSSRVPSSSSISSSSGLP------ 411
S S+A TG + L +T + SP SS ++++ S+ P
Sbjct: 3547 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 3606
Query: 412 --YHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSS----SSGHPCMSVSSL 465
+H S+ +SP + S +SS S+ S +P + ++ S+ P +S S
Sbjct: 3607 TTFH---SSPRSPATTLSPASTTSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHST 3663
Query: 466 TLTGGPDGSPHPDPSAGAKPCGSS 489
T P + A GSS
Sbjct: 3664 TSHSSPGSTDTTLLPASTTTSGSS 3687
Score = 52.4 bits (124), Expect = 1e-06
Identities = 103/483 (21%), Positives = 176/483 (36%), Gaps = 49/483 (10%)
Query: 27 LPGT-----LAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSA 81
LPG+ L+++ TF + PT SP G G+ S +S S S+ S++S A
Sbjct: 2314 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST-TSRSQPGSTHSTVSPA 2372
Query: 82 RSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHS 141
++ G S S+ + S PG+ + V + +S++G ++ +S
Sbjct: 2373 STTTPGLSEEST--------TVYSSSPGSTETTV-FPRTPTTSVRGEEPTTFHSRPASTH 2423
Query: 142 GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQT 201
+ + ++S + S++F S +S Q G + L T D PS G + ++
Sbjct: 2424 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2483
Query: 202 FGVSSS---GQSVSSNQRPCSSD---IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVV 255
++S G+S S P S++ +P SP + + S + S S P
Sbjct: 2484 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPS-LSEKSTTFYTSPRSPDATLSPATT 2542
Query: 256 VVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG----GSSDSYLVPGM 311
S S G P ++ + GS+D+ L+P
Sbjct: 2543 T-----SSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPAS 2597
Query: 312 TYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQP 371
T + G + SPG A P + F S S+ P
Sbjct: 2598 TTTSGP------SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFP 2651
Query: 372 VGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSI----SSSSGLPYHPCGSASQSPCSPPG 427
T + + SP ++ P+SS+ S+ HP +++ + SPP
Sbjct: 2652 DSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHP--ASTHTTPSPPS 2709
Query: 428 TGSF---SSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAK 484
T + S++ +S G + S++SGH S S PD S SA +
Sbjct: 2710 TATAPVEESTTYHRSPGSTPTTHFPASSTTSGH---SEKSTIFHSSPDASGTTPSSAHST 2766
Query: 485 PCG 487
G
Sbjct: 2767 TSG 2769
Score = 49.7 bits (117), Expect = 7e-06
Identities = 99/473 (20%), Positives = 178/473 (37%), Gaps = 56/473 (11%)
Query: 26 LLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSS-----YSGSSSSGSSISS 80
L P A S+ +P P S L G ++G S YS S +++S
Sbjct: 4289 LFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 4347
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSH 140
A S++ S +++ + +PG+ ++ SS +++ G S S ++SH
Sbjct: 4348 A---------STTSSGVSEESTTSHSRPGSMHTTAFPSS---TTMPGVSQES----TASH 4391
Query: 141 SGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA----LPTNDNSYRGILNPSQPGQSS 196
S S GS + S S+++SS S++F GS LP N + G+L S P SS
Sbjct: 4392 S-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA-SGLLEASTPVHSS 4449
Query: 197 SSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVV 256
+ S +S +G + + P+S + + + ++ S + G
Sbjct: 4450 TGSPHTTLSPAGSTTRQGESTTFQSWPNSKDTTPAPPTTTSAFVELSTTSHGSPSSTPTT 4509
Query: 257 VDQHGSGAPG------VVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP- 309
S G V P + P + + + Y GS+ + P
Sbjct: 4510 HFSASSTTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTTYHSSPGSTQTMHFPE 4569
Query: 310 -GMTYSKGKIYPVGYFTKENPVKGSPGV--------PSFAAGPPISEGKYFSSNPIIPSQ 360
T +G+ + + + + +P S+ + P + +F + +
Sbjct: 4570 SNTTSGRGEESTTSHSSTTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGR 4629
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTG---SKGPCSPSSSRVPSSSSISSSSGLP--YHPC 415
S S+A TG + L +T + SP SS ++++ S+ P
Sbjct: 4630 SEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKS 4689
Query: 416 GSASQSPCSPPGTGSFSSSSS----SQSSGKIILQPCGSKSSSSGHPCMSVSS 464
+ SP S P T FS+SS+ S+ S + P + ++ S P S +S
Sbjct: 4690 TTFHSSPSSTP-TTHFSASSTTLGRSEESTTVHSSPVATATTPS--PARSTTS 4739
Score = 49.3 bits (116), Expect = 9e-06
Identities = 92/428 (21%), Positives = 151/428 (35%), Gaps = 45/428 (10%)
Query: 71 SSSSGSSISSARSSGGGSSGSSSGS-SIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGAS 129
S +S + SS RS S +S S + + + +PG+ +S VS +S + L S
Sbjct: 1241 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 1300
Query: 130 GSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNP 189
+ S S + HS ++S H ++F +S + L T D++ G+
Sbjct: 1301 TTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAS----THTTLFTEDSTTSGLTEE 1356
Query: 190 SQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGG 249
S S +S G+ ++ + + S+ P S S G +S P+ + SG
Sbjct: 1357 STAFPGSPASTQTGLPATLTTADLGEE--STTFPSSSGSTGTKLS------PARSTTSG- 1407
Query: 250 QRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP 309
G P + LPG P P S+ + + S D+ L P
Sbjct: 1408 ---------LVGESTPSRLSPSSTETTTLPGSPTTP--SLSEKSTTFYTSPRSPDATLSP 1456
Query: 310 GMTYSKGKIYPVGYFTKENPVKGS-PGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIA 368
T S G ++E+ S PG A P + S P S S+
Sbjct: 1457 ATTTSSG-------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 1509
Query: 369 FQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS--SSGLPYHPCGSASQSPCSPP 426
P T L +T P ++ +P + S + P H + + +P
Sbjct: 1510 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1569
Query: 427 GTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVS-----SLTLTGGPDGSPHPDPSA 481
SS+S+ Q S S ++ P + + S T P +P SA
Sbjct: 1570 -----SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSA 1624
Query: 482 GAKPCGSS 489
+ G S
Sbjct: 1625 SSTTLGRS 1632
Score = 48.9 bits (115), Expect = 1e-05
Identities = 99/449 (22%), Positives = 167/449 (37%), Gaps = 63/449 (14%)
Query: 26 LLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSS-----YSGSSSSGSSISS 80
L P A S+ +P P S L G ++G S YS S +++S
Sbjct: 1649 LFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1707
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSH 140
A ++ G S S+ S G + + PG+ +++ G S S ++SH
Sbjct: 1708 ASTTSSGVSEESTTSHSRPGSTHTTAFPGS------------TTMPGVSQES----TASH 1751
Query: 141 SGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA----LPTNDNSYRGILNPSQPGQSS 196
S S GS + S S+++SS S++F GS LP N + G+L S P SS
Sbjct: 1752 S-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA-SGLLEASTPVHSS 1809
Query: 197 SSSQTFGVSSS------GQSVSSNQRPCSSD-IPDSPCSGGPIV-----SHSGP-YIPSS 243
+ S +S + G+S + P S D +P P + V SH P P++
Sbjct: 1810 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1869
Query: 244 HSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSS 303
H + S V P + P + + + Y GS+
Sbjct: 1870 HFSASS-------TTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGST 1922
Query: 304 DSYLVPGMTYSKGKIYP--VGYFTKENPVKGSPGV--------PSFAAGPPISEGKYFSS 353
+ P + + G+ + + + + P S+ + P + +F
Sbjct: 1923 QTMHFPESSTASGRSEESRTSHSSTTHTISSPPSTTSALVEEPTSYHSSPGSTATTHFPD 1982
Query: 354 NPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTG---SKGPCSPSSSRVPSSSSISSSSGL 410
+ +S S+A TG + L +T + SP SS ++++ S+
Sbjct: 1983 SSTTSGRSEESTASHSSQDATGTIVLPARSTTSVLLGESTTSPISSGSMETTALPGSTTT 2042
Query: 411 P--YHPCGSASQSPCSPPGTGSFSSSSSS 437
P + SP SP T S +S++SS
Sbjct: 2043 PGLSEKSTTFHSSPRSPATTLSPASTTSS 2071
Score = 47.4 bits (111), Expect = 3e-05
Identities = 108/472 (22%), Positives = 175/472 (37%), Gaps = 64/472 (13%)
Query: 30 TLAKSIGTFSDPCKDPTRI-TSPNDPCLTGKGDSSGFS--------SYSGSSSSGSSISS 80
T++ + T S ++PT +SP T DSS S S+S ++G+ +
Sbjct: 4590 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 4649
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSH 140
ARS+ G S+ S I+ G + PG+ + S ++ + S+ S+
Sbjct: 4650 ARSTTSVLLGESTTSPISSGSMETTALPGS--TTTPGLSEKSTTFHSSPSSTPTTHFSAS 4707
Query: 141 SGSSGSHSGSSSSHSS-----SSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQS 195
S + G S++ HSS ++ S S++S V +A ++ S + + P S
Sbjct: 4708 STTLGRSEESTTVHSSPVATATTPSPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTAS 4767
Query: 196 SSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGP------YIPSSHSVSGG 249
S ++ SS S+ +S + + P S HS P + P S + SG
Sbjct: 4768 GRSEESRTSHSSTTHTISSPPSTTSALVEEPTS-----YHSSPGSIATTHFPESSTTSGR 4822
Query: 250 QRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP 309
H S P +NG IT + + + S+ Y+ P
Sbjct: 4823 SEESTA---SHSS---------PDTNG---------ITPLPAHFTTSGRIAESTTFYISP 4861
Query: 310 GM--TYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPI-IPSQSAASSA 366
G T G K + S P P S P + SQ+ ++
Sbjct: 4862 GSMETTLASTATTPGLSAKSTILYSSSRSPDQTLSPASMTSSSISGEPTSLYSQAESTHT 4921
Query: 367 IAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS---SSISSSSGLPYHPCGSA--SQS 421
AF P T L +T P S ++ P S SS + P+ GSA + S
Sbjct: 4922 TAF-PASTTTSGLSQESTTFHSKPGSTETTLSPGSITTSSFAQEFTTPHSQPGSALSTVS 4980
Query: 422 PCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHP-CMSVSSLTLTGGPD 472
P S G S++ SS P +++++ H MS+ S T PD
Sbjct: 4981 PASTTVPGLSEESTTFYSS------PGSTETTAFSHSNTMSIHSQQSTPFPD 5026
Score = 47.0 bits (110), Expect = 4e-05
Identities = 120/536 (22%), Positives = 183/536 (34%), Gaps = 107/536 (19%)
Query: 28 PGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSG------------ 75
PG KS +S P SP+ L SSG S S +S S
Sbjct: 630 PGLSEKSTTFYSSP-------RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGS 682
Query: 76 ------SSISSARSSGGG------SSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
S S+A S G S GS++ SS+ + +PG+ + + + + S
Sbjct: 683 TTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 742
Query: 124 SLQGASGSSQLGSSSSH-----SGSSGSHSGSSSSHSSSSS-----------SFQFSSSS 167
L AS + S H +GS+ S++ HS SS S S+
Sbjct: 743 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 802
Query: 168 FQVGNGSALPTNDNSYR----GILNPSQPGQSS-SSSQTF------GVSSSGQSVSSNQR 216
G+ S++PT S R G++ S SS S+QT S G+ +++
Sbjct: 803 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 862
Query: 217 PCSSDIPDSPCSGGPIVS-----HSGP------YIPSSHSVSGGQRPVVVVVDQHGSGAP 265
+ I +P + +V HS P + P S + SG R A
Sbjct: 863 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG--RSEESTASHSSQDAT 920
Query: 266 GVVQGPPCSNGG--LPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGY 323
G + P S L PI+S GS ++ +PG T + G
Sbjct: 921 GTIVLPARSTTSVLLGESTTSPISS------------GSMETTALPGSTTTP------GL 962
Query: 324 FTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGG 383
+ SP P+ P + S S+ P T L
Sbjct: 963 SERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS 1022
Query: 384 STGSKGPCSPSSSRVPSSSSIS--SSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
+T P S ++ +P+S++ S S H ++ + SP GS ++ S Q S
Sbjct: 1023 TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP---GSTTALSFGQEST 1079
Query: 442 KIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGA-----KPCGSSSAG 492
P S H + S T +G + S S G+ P S+S G
Sbjct: 1080 TFHSNP------GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 1129
Score = 46.2 bits (108), Expect = 7e-05
Identities = 99/478 (20%), Positives = 166/478 (34%), Gaps = 62/478 (12%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
T P P T +S+ SS+ ++ SA S+ G S S+ ++ A + P
Sbjct: 1841 TMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST--TVHSSPVATATTP 1898
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
S S ++ + GS+Q S +SG S +SHSS++ + S+
Sbjct: 1899 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST- 1957
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDI------ 222
SAL SY S PG ++++ ++SG+S S S D
Sbjct: 1958 ----TSALVEEPTSYH-----SSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVL 2008
Query: 223 -------------PDSPCSGGPIVSHSGPYIPSSHSVS-------GGQRPVVVVVDQHGS 262
SP S G + + + P ++ +S R + +
Sbjct: 2009 PARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSEKSTTFHSSPRSPATTLSPAST 2068
Query: 263 GAPGVVQGPPCSNG--GLPGKPCPPITSVDKSYGGYEVVG----GSSDSYLVPGMTYSKG 316
+ GV + S+ G P ++ + GS+D+ L+P T + G
Sbjct: 2069 TSSGVSEESTTSHSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLLPASTTTSG 2128
Query: 317 KIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGG 376
+ SPG A P + F S S+ P T
Sbjct: 2129 P------SQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPDSTTS 2182
Query: 377 VQLCGGGSTGSKGPCSPSSSRVPSSSSI----SSSSGLPYHPCGSASQSPCSPPGTGSF- 431
+ + SP ++ P+SS+ S+ HP +++ + SPP T +
Sbjct: 2183 SGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHP--ASTHTTPSPPSTATAP 2240
Query: 432 --SSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCG 487
S++ +S G + S++SGH S S PD S SA + G
Sbjct: 2241 VEESTTYHRSPGSTPTTHFPASSTTSGH---SEKSTIFHSSPDASGTTPSSAHSTTSG 2295
Score = 44.3 bits (103), Expect = 3e-04
Identities = 101/482 (20%), Positives = 176/482 (36%), Gaps = 42/482 (8%)
Query: 27 LPGT-----LAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSA 81
LPG+ L+++ TF + PT SP G G+ S +S S S+ S++S A
Sbjct: 2788 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST-TSRSQPGSTHSTVSPA 2846
Query: 82 RSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHS 141
++ G S S+ + S PG+ + V + + +S++G ++ +S
Sbjct: 2847 STTTPGLSEEST--------TVYSSSPGSTETTV-FPRSTTTSVRGEEPTTFHSRPASTH 2897
Query: 142 GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQT 201
+ + ++S + S++F S +S Q G + L T D PS G + ++
Sbjct: 2898 TTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTTLSP 2957
Query: 202 FGVSSS---GQSVSSNQRPCSSD---IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVV 255
++S G+S S P S++ +P SP + P +S +S
Sbjct: 2958 ARSTTSGLVGESTPSRLSPSSTETTTLPGSPTT--PSLSEKSTTFYTSPRSPDATLSPAT 3015
Query: 256 VVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSK 315
S P S + + + GS+++ L PG T +
Sbjct: 3016 TTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTASHSSQGSTEATLSPGSTTAS 3075
Query: 316 GKIYPVGYFTKENPVKGSPGVPSFAAGP--PISEGKYFSSNPIIPSQSAASSAIAFQPVG 373
+ SPG P I+ G +S P S S P
Sbjct: 3076 ------SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP--THSSTGSLHTTLTPAS 3127
Query: 374 TGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTG-SFS 432
+ L +T P S ++ P ++ + P + P S P T S S
Sbjct: 3128 STSAGLQEESTTFQSWPSSSDTTPSPPGTTAA-----PVEVSTTYHSRPSSTPTTHFSAS 3182
Query: 433 SSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPS--AGAKPCGSSS 490
S++ +S + + ++ P S +S+ L G P SP S A P +++
Sbjct: 3183 STTLGRSEESTTVHSSPGATGTALFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTT 3241
Query: 491 AG 492
AG
Sbjct: 3242 AG 3243
Score = 43.9 bits (102), Expect = 4e-04
Identities = 113/495 (22%), Positives = 184/495 (37%), Gaps = 68/495 (13%)
Query: 27 LPGT-----LAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSA 81
LPG+ L+++ TF + PT SP G G+ S +S S S+ S++S A
Sbjct: 3871 LPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEEST-TSRSQPGSTHSTVSPA 3929
Query: 82 RSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHS 141
++ G S S+ + S PG+ + V S + S + + +S+H+
Sbjct: 3930 STTTPGLSEEST--------TVYSSSPGSTETTVFPRSTTTSVRREEPTTFHSRPASTHT 3981
Query: 142 GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQ-----SS 196
+ + ++S + S++F S +S Q G + L T D PS G S
Sbjct: 3982 -TLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLGEESTTFPSSSGSTGTKLSP 4040
Query: 197 SSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPV 253
+ S T G+ G+S S P S++ +P SP + + S + S S P
Sbjct: 4041 ARSTTSGL--VGESTPSRLSPSSTETTTLPGSPTTPS-LSEKSTTFYTSPRSPDATLSPA 4097
Query: 254 VVV---VDQHGS---GAPGVVQ----GPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSS 303
V + S PG + GL +P +S GS+
Sbjct: 4098 TTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSGLSQEPTTSHSS-----------QGST 4146
Query: 304 DSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGP--PISEGKYFSSNPIIPSQS 361
++ L PG T + + SPG P I+ G +S P S
Sbjct: 4147 EATLSPGSTTAS------SLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTP--THSS 4198
Query: 362 AASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSS-RVPSSSSISSSSGLPYHPCGSASQ 420
S P + L +T P S ++ PS++++ YH
Sbjct: 4199 TGSLHTTLTPASSTSTGLQEESTTFQSWPSSSDTTPSPPSTTAVPVEVSTTYH------S 4252
Query: 421 SPCSPPGTG-SFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDP 479
P S P T S SS++ +S + + ++ P S +S+ L G P SP
Sbjct: 4253 RPSSTPTTHFSASSTTLGRSEESTTVHSSPGATGTALFPTRSATSV-LVGEPTTSPISSG 4311
Query: 480 S--AGAKPCGSSSAG 492
S A P +++AG
Sbjct: 4312 STETTALPGSTTTAG 4326
Score = 42.7 bits (99), Expect = 8e-04
Identities = 110/509 (21%), Positives = 180/509 (35%), Gaps = 57/509 (11%)
Query: 20 LLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS 79
LL A G +S + S P T ++ + L+ +S+ F S GS+ +
Sbjct: 2119 LLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2178
Query: 80 SARSSGGGSSG----SSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSS----LQGASGS 131
S SSG + SS+GS A S PG ++ + S+ ++ +
Sbjct: 2179 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTAT 2238
Query: 132 SQLGSSSSHSGSSGS-------HSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR 184
+ + S+++ S GS S ++S HS S+ F S + SA T
Sbjct: 2239 APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 2298
Query: 185 GILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHS-GPYIPSS 243
+ PG + ++ ++ G S +S S P + S + S G +S
Sbjct: 2299 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 2358
Query: 244 HSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGK------PCPPITSVDKSYGGYE 297
S G V + PG+ + PG P P TSV G E
Sbjct: 2359 RSQPGSTHS---TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRTPTTSV----RGEE 2411
Query: 298 VVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKG-------SPGVP-SFAAGPP--ISE 347
P +S+ FT+++ G PG P S G P ++
Sbjct: 2412 -----------PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTT 2460
Query: 348 GKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS---SSI 404
+ PS S+ S+ P + L G + P S ++ +P S S+
Sbjct: 2461 ADLGEESTTFPS-SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSL 2519
Query: 405 SSSSGLPYHPCGS--ASQSPCSPPGTGSFSSSSSSQSS-GKIILQPCGSKSSSSGHPCMS 461
S S Y S A+ SP + +G SS+S S G +++ G S
Sbjct: 2520 SEKSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTPGLSRHS 2579
Query: 462 VSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
+S + G D + P + + P S+
Sbjct: 2580 TTSHSSPGSTDTTLLPASTTTSGPSQEST 2608
Score = 42.0 bits (97), Expect = 0.001
Identities = 111/518 (21%), Positives = 181/518 (34%), Gaps = 63/518 (12%)
Query: 20 LLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS 79
LL A G +S + S P T ++ + L+ +S+ F S GS+ +
Sbjct: 2593 LLPASTTTSGPSQESTTSHSSPGSTDTALSPGSTTALSFGQESTTFHSSPGSTHTTLFPD 2652
Query: 80 SARSSGGGSSG----SSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSS----LQGASGS 131
S SSG + SS+GS A S PG ++ + S+ ++ +
Sbjct: 2653 STTSSGIVEASTRVHSSTGSPRTTLSPASSTSPGLQGESTTFQTHPASTHTTPSPPSTAT 2712
Query: 132 SQLGSSSSHSGSSGS-------HSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR 184
+ + S+++ S GS S ++S HS S+ F S + SA T
Sbjct: 2713 APVEESTTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGTTPSSAHSTTSGRGE 2772
Query: 185 GILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHS-GPYIPSS 243
+ PG + ++ ++ G S +S S P + S + S G +S
Sbjct: 2773 STTSRISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTS 2832
Query: 244 HSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPI--TSVDKSYGGYEVVGG 301
S G V + PG+ + PG + S S G E
Sbjct: 2833 RSQPGSTHS---TVSPASTTTPGLSEESTTVYSSSPGSTETTVFPRSTTTSVRGEE---- 2885
Query: 302 SSDSYLVPGMTYSKGKIYPVGYFTKENPVKG-------SPGVP-SFAAGPP--ISEGKYF 351
P +S+ FT+++ G PG P S G P ++
Sbjct: 2886 -------PTTFHSRPASTHTTLFTEDSTTSGLTEESTAFPGSPASTQTGLPATLTTADLG 2938
Query: 352 SSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLP 411
+ PS S+ S+ P + L G + P S ++ +P S + S S
Sbjct: 2939 EESTTFPS-SSGSTGTTLSPARSTTSGLVGESTPSRLSPSSTETTTLPGSPTTPSLS--- 2994
Query: 412 YHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGP 471
+ SP SP T S ++++SS S+ SS+ H S T P
Sbjct: 2995 -EKSTTFYTSPRSPDATLSPATTTSSGV----------SEESSTSH--SQPGSTHTTAFP 3041
Query: 472 DGSP----HPDPSAGAKPCGSSSAGKIPCRSIRDILAQ 505
D + +P+A GS+ A P + L Q
Sbjct: 3042 DSTTTSGLSQEPTASHSSQGSTEATLSPGSTTASSLGQ 3079
Score = 39.3 bits (90), Expect = 0.009
Identities = 108/506 (21%), Positives = 173/506 (34%), Gaps = 124/506 (24%)
Query: 16 GMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSG 75
G ++L L + G K++G SP D G G + GFS S
Sbjct: 90 GESVVVLVHLWMTGARVKNLGL--------VEFASPGDD---GDGRAEGFSLGLPLSEQA 138
Query: 76 -----------------SSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
S+ S G + +S G + + S P T +S S
Sbjct: 139 RAAGAREKERQETVINHSTFSGFSQITGSTVNTSIGGNTTSASTPSSSDPFTTFSDYGVS 198
Query: 119 SGSGSSLQGASGSSQLGSSSSHSG----SSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS 174
+ + G++ + SS++SG S+ SHSG ++ ++ S S++S VG
Sbjct: 199 V---TFITGSTATKHFLDSSTNSGHSEESTVSHSGPGATGTTLFPSH--SATSVFVGEPK 253
Query: 175 ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVS 234
P S P S+ T G+S + S+ R + + + +
Sbjct: 254 TSPITSASMETTALPG-------STTTAGLSEKSTTFYSSPRSPDRTLSPARTTSSGVSE 306
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
S +SHS G P + + PGV Q S+
Sbjct: 307 KS----TTSHSRPG---PTHTIAFPDSTTMPGVSQESTASHS------------------ 341
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
+ GS+D+ L PG T P P +F + P ++
Sbjct: 342 ----IPGSTDTTLSPGTT---------------TPSSLGPESTTFHSSPG------YTKT 376
Query: 355 PIIPSQSAASSAI-AFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYH 413
+P + S + A PV + STGS P ++ PSSS+ +
Sbjct: 377 TRLPDNTTTSGLLEASTPVHS---------STGS-----PHTTLSPSSSTTHEGEPTTFQ 422
Query: 414 PCGSASQSPCSPPGTGS-FSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPD 472
S+ + +P GT S F S++ S SS+ S SS TL +
Sbjct: 423 SWPSSKDTSPAPSGTTSAFVKLSTTYH----------SSPSSTPTTHFSASSTTLGHSEE 472
Query: 473 GSP-HPDPSAGA---KPCGSSSAGKI 494
+P H P A A P S+++G +
Sbjct: 473 STPVHSSPVATATTPPPARSATSGHV 498
Score = 35.8 bits (81), Expect = 0.099
Identities = 43/153 (28%), Positives = 66/153 (43%), Gaps = 5/153 (3%)
Query: 30 TLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGG-- 87
TL+ + T S +PT + S + T +S ++ SG S ++ S S
Sbjct: 4894 TLSPASMTSSSISGEPTSLYSQAESTHTTAFPAS--TTTSGLSQESTTFHSKPGSTETTL 4951
Query: 88 SSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSH 147
S GS + SS AQ + +PG+ S VS +S + L S ++ S S ++ SH
Sbjct: 4952 SPGSITTSSFAQEFTTPHSQPGSALSTVSPASTTVPGLSEES-TTFYSSPGSTETTAFSH 5010
Query: 148 SGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
S + S HS S+ F S + L T D
Sbjct: 5011 SNTMSIHSQQSTPFPDSPGFTHTVLPATLTTTD 5043
>gi|186928829 dermokine isoform 4 precursor [Homo sapiens]
Length = 386
Score = 64.3 bits (155), Expect = 3e-10
Identities = 61/213 (28%), Positives = 86/213 (40%), Gaps = 27/213 (12%)
Query: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
M APW G+ G G P + G + P R ++ N+ C
Sbjct: 186 MNPQGAPW-GQGGNGGP----------PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
SG S S+S G S S + SSG GS+G ++ S + G S+GS G+ SSG
Sbjct: 235 SGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
Query: 121 SGSSLQGASGS-----SQLGSSSSHSGSSGSHSG--------SSSSHSSSSSSFQFSSSS 167
+ +G SGS S GSSS + G SG +G + + S S Q S +S
Sbjct: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
Query: 168 FQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQ 200
+ N N S G +N + SS+
Sbjct: 352 PGMFNFDTFWKNFKSKLGFINWDAINKDQRSSR 384
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/145 (33%), Positives = 64/145 (44%), Gaps = 16/145 (11%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
G+ S S+ + + S GG S +S G S +Q GS+GS G+ + SS GS
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGS 272
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
S +SG S GSS SG+SG G S S SS SS SSS G+G
Sbjct: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS-TGSSSGNHGGSGGG-------- 323
Query: 184 RGILNPSQPGQSSSSSQTFGVSSSG 208
N +PG ++ G SG
Sbjct: 324 ----NGHKPGCEKPGNEARGSGESG 344
Score = 47.0 bits (110), Expect = 4e-05
Identities = 49/160 (30%), Positives = 72/160 (45%), Gaps = 14/160 (8%)
Query: 58 GKGDSSGFSS-----YSGSS--SSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGT 110
G+G+ G + Y G+S S G + A GG+ G + + QG A +PG
Sbjct: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA---QPGY 217
Query: 111 GYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQV 170
G + S + G + SGS G SS+ G SGS SGSS S S+ ++ SS
Sbjct: 218 GSVRAS-NQNEGCTNPPPSGSG--GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
Query: 171 GNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQS 210
G+ S ++ S G S + S S++ SS+G S
Sbjct: 275 GSSSG-GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Score = 39.3 bits (90), Expect = 0.009
Identities = 55/194 (28%), Positives = 67/194 (34%), Gaps = 27/194 (13%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGS----SSGSSIAQGGSAGSFKPGTGYSQV 115
G G + G G S+GS G+ QGG+ G GT
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 116 SYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
G GS +S ++ SGS GSS+S S S S SS G+GS
Sbjct: 212 VAQPGYGSVR-----ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ---SGSS---GSGS- 259
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSH 235
DN+ N S G SSS S + G S SS S S S G
Sbjct: 260 --NGDNN-----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312
Query: 236 SGPYIPSSHSVSGG 249
S +H SGG
Sbjct: 313 SS----GNHGGSGG 322
Score = 33.5 bits (75), Expect = 0.49
Identities = 97/432 (22%), Positives = 147/432 (34%), Gaps = 97/432 (22%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
CL G G++ S G S+G++I A G G + S G A G AG G S+
Sbjct: 15 CL-GSGEAGPLQS--GEESTGTNIGEALGHGLGDA-LSEGVGKAIGKEAG----GAAGSK 66
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS 174
VS + G G+ +G Q+ + + + G+ G ++ H+ ++ + + V
Sbjct: 67 VSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAA-HALGNTGHEIGRQAEDVIRHG 124
Query: 175 ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVS 234
A S++G+ PG + + +S G + +Q +P G
Sbjct: 125 ADAVR-GSWQGV-----PGHNGAWE-----TSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
H P + + S G P QG P GG G P ++G
Sbjct: 174 HG---YPGNSAGSFGMNP----------------QGAPWGQGGNGGPP---------NFG 205
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
T ++G + GY V+ S PP G S++
Sbjct: 206 -----------------TNTQGAVAQPGY----GSVRASNQNEGCTNPPPSGSGGGSSNS 244
Query: 355 PIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHP 414
G G G +GS G + SS SSS SS
Sbjct: 245 ------------------GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
Query: 415 CGSASQSPCSPPGTGSFSS--SSSSQSSGKIILQPCGSKSSSSGHP--CMSVSSLTLTGG 470
GS+ S S +GS SS SS+ SSG G +GH C + G
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGN-----HGGSGGGNGHKPGCEKPGNEARGSG 341
Query: 471 PDGSPHPDPSAG 482
G + + S G
Sbjct: 342 ESGIQNSETSPG 353
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 11/122 (9%)
Query: 371 PVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGS 430
P G+GG GG +GS+ S SS S S+G + S S S G S
Sbjct: 234 PSGSGGGSSNSGGGSGSQ-----------SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
Query: 431 FSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
SS S + GS+SS S + +GG +G G + GS
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
Query: 491 AG 492
+G
Sbjct: 343 SG 344
Score = 31.2 bits (69), Expect = 2.5
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 416 GSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTG-GPDGS 474
G+ +Q + PG GS +S+Q+ G P GS SS S S +G G +G
Sbjct: 205 GTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
Query: 475 PHPDPSAGAKPCGSSSAG 492
+ S+G GSSS G
Sbjct: 263 NNNGSSSGGSSSGSSSGG 280
>gi|33504489 dermokine isoform 2 precursor [Homo sapiens]
Length = 476
Score = 63.9 bits (154), Expect = 3e-10
Identities = 59/201 (29%), Positives = 82/201 (40%), Gaps = 27/201 (13%)
Query: 1 MGSSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKG 60
M APW G+ G G P + G + P R ++ N+ C
Sbjct: 186 MNPQGAPW-GQGGNGGP----------PNFGTNTQGAVAQPGYGSVRASNQNEGCTNPPP 234
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
SG S S+S G S S + SSG GS+G ++ S + G S+GS G+ SSG
Sbjct: 235 SGSGGGS---SNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSSGGSSG 291
Query: 121 SGSSLQGASGS-----SQLGSSSSHSGSSGSHSG--------SSSSHSSSSSSFQFSSSS 167
+ +G SGS S GSSS + G SG +G + + S S Q S +S
Sbjct: 292 NSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGESGIQNSETS 351
Query: 168 FQVGNGSALPTNDNSYRGILN 188
+ N N S G +N
Sbjct: 352 PGMFNFDTFWKNFKSKLGFIN 372
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/145 (33%), Positives = 64/145 (44%), Gaps = 16/145 (11%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
G+ S S+ + + S GG S +S G S +Q GS+GS G+ + SS GS
Sbjct: 216 GYGSVRASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGS---GSNGDNNNGSSSGGS 272
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
S +SG S GSS SG+SG G S S SS SS SSS G+G
Sbjct: 273 SSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSS-TGSSSGNHGGSGGG-------- 323
Query: 184 RGILNPSQPGQSSSSSQTFGVSSSG 208
N +PG ++ G SG
Sbjct: 324 ----NGHKPGCEKPGNEARGSGESG 344
Score = 47.0 bits (110), Expect = 4e-05
Identities = 49/160 (30%), Positives = 72/160 (45%), Gaps = 14/160 (8%)
Query: 58 GKGDSSGFSS-----YSGSS--SSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGT 110
G+G+ G + Y G+S S G + A GG+ G + + QG A +PG
Sbjct: 161 GQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGAVA---QPGY 217
Query: 111 GYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQV 170
G + S + G + SGS G SS+ G SGS SGSS S S+ ++ SS
Sbjct: 218 GSVRAS-NQNEGCTNPPPSGSG--GGSSNSGGGSGSQSGSSGSGSNGDNNNGSSSGGSSS 274
Query: 171 GNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQS 210
G+ S ++ S G S + S S++ SS+G S
Sbjct: 275 GSSSG-GSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGSS 313
Score = 39.3 bits (90), Expect = 0.009
Identities = 55/194 (28%), Positives = 67/194 (34%), Gaps = 27/194 (13%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGS----SSGSSIAQGGSAGSFKPGTGYSQV 115
G G + G G S+GS G+ QGG+ G GT
Sbjct: 152 GSQGGLGGQGQGNPGGLGTPWVHGYPGNSAGSFGMNPQGAPWGQGGNGGPPNFGTNTQGA 211
Query: 116 SYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
G GS +S ++ SGS GSS+S S S S SS G+GS
Sbjct: 212 VAQPGYGSVR-----ASNQNEGCTNPPPSGSGGGSSNSGGGSGSQ---SGSS---GSGS- 259
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSH 235
DN+ N S G SSS S + G S SS S S S G
Sbjct: 260 --NGDNN-----NGSSSGGSSSGSSSGGSSGGSSGGSSGNSGGSRGDSGSESSWGSSTGS 312
Query: 236 SGPYIPSSHSVSGG 249
S +H SGG
Sbjct: 313 SS----GNHGGSGG 322
Score = 33.5 bits (75), Expect = 0.49
Identities = 97/432 (22%), Positives = 147/432 (34%), Gaps = 97/432 (22%)
Query: 55 CLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ 114
CL G G++ S G S+G++I A G G + S G A G AG G S+
Sbjct: 15 CL-GSGEAGPLQS--GEESTGTNIGEALGHGLGDA-LSEGVGKAIGKEAG----GAAGSK 66
Query: 115 VSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS 174
VS + G G+ +G Q+ + + + G+ G ++ H+ ++ + + V
Sbjct: 67 VSEALGQGTREAVGTGVRQVPGFGA-ADALGNRVGEAA-HALGNTGHEIGRQAEDVIRHG 124
Query: 175 ALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVS 234
A S++G+ PG + + +S G + +Q +P G
Sbjct: 125 ADAVR-GSWQGV-----PGHNGAWE-----TSGGHGIFGSQGGLGGQGQGNPGGLGTPWV 173
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
H P + + S G P QG P GG G P ++G
Sbjct: 174 HG---YPGNSAGSFGMNP----------------QGAPWGQGGNGGPP---------NFG 205
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
T ++G + GY V+ S PP G S++
Sbjct: 206 -----------------TNTQGAVAQPGY----GSVRASNQNEGCTNPPPSGSGGGSSNS 244
Query: 355 PIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHP 414
G G G +GS G + SS SSS SS
Sbjct: 245 ------------------GGGSGSQSGSSGSGSNGDNNNGSSSGGSSSGSSSGGSSGGSS 286
Query: 415 CGSASQSPCSPPGTGSFSS--SSSSQSSGKIILQPCGSKSSSSGHP--CMSVSSLTLTGG 470
GS+ S S +GS SS SS+ SSG G +GH C + G
Sbjct: 287 GGSSGNSGGSRGDSGSESSWGSSTGSSSGN-----HGGSGGGNGHKPGCEKPGNEARGSG 341
Query: 471 PDGSPHPDPSAG 482
G + + S G
Sbjct: 342 ESGIQNSETSPG 353
Score = 31.6 bits (70), Expect = 1.9
Identities = 34/122 (27%), Positives = 46/122 (37%), Gaps = 11/122 (9%)
Query: 371 PVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGS 430
P G+GG GG +GS+ S SS S S+G + S S S G S
Sbjct: 234 PSGSGGGSSNSGGGSGSQ-----------SGSSGSGSNGDNNNGSSSGGSSSGSSSGGSS 282
Query: 431 FSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
SS S + GS+SS S + +GG +G G + GS
Sbjct: 283 GGSSGGSSGNSGGSRGDSGSESSWGSSTGSSSGNHGGSGGGNGHKPGCEKPGNEARGSGE 342
Query: 491 AG 492
+G
Sbjct: 343 SG 344
Score = 31.2 bits (69), Expect = 2.5
Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 3/78 (3%)
Query: 416 GSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTG-GPDGS 474
G+ +Q + PG GS +S+Q+ G P GS SS S S +G G +G
Sbjct: 205 GTNTQGAVAQPGYGSV--RASNQNEGCTNPPPSGSGGGSSNSGGGSGSQSGSSGSGSNGD 262
Query: 475 PHPDPSAGAKPCGSSSAG 492
+ S+G GSSS G
Sbjct: 263 NNNGSSSGGSSSGSSSGG 280
>gi|28559039 mediator complex subunit 1 [Homo sapiens]
Length = 1581
Score = 62.8 bits (151), Expect = 8e-10
Identities = 119/446 (26%), Positives = 153/446 (34%), Gaps = 119/446 (26%)
Query: 50 SPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPG 109
S + P K D+ G S SSS + S+GG S S+G S G A P
Sbjct: 1005 SKDKPPKRKKADTEGKSP--SHSSSNRPFTPPTSTGGSKSPGSAGRSQTPPGVATPPIPK 1062
Query: 110 TGYSQVSYSSGSGSSLQGASGSSQLGSSSSH----SGSSGSHSGSSSSHSSSSSSFQFSS 165
++Q G+ +G SSH S S S SGS S HS SSSS +S
Sbjct: 1063 I-------------TIQIPKGTVMVGKPSSHSQYTSSGSVSSSGSKSHHSHSSSSSSSAS 1109
Query: 166 SSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDS 225
+S G + S+ SSSS + + SS S S+Q SS
Sbjct: 1110 TS-----------------GKMKSSKSEGSSSSKLSSSMYSSQGSSGSSQSKNSSQSGGK 1152
Query: 226 PCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGL-PGKPCP 284
P S PI H SS S S +P G P + P S + P P
Sbjct: 1153 PGS-SPITKHG----LSSGSSSTKMKP---------QGKPSSLMNPSLSKPNISPSHSRP 1198
Query: 285 PITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPP 344
P G SD P PV G+P PS A P
Sbjct: 1199 P---------------GGSDKLASP-----------------MKPVPGTP--PSSKAKSP 1224
Query: 345 ISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCG-GGSTGSKGPCSPSSSRVPSSSS 403
IS G+GG + G S+G K SSS + SS S
Sbjct: 1225 ISS-------------------------GSGGSHMSGTSSSSGMK-----SSSGLGSSGS 1254
Query: 404 ISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVS 463
+S + + C ++S S S +GS SSS +Q P +K S +
Sbjct: 1255 LSQKTPPSSNSCTASSSSFSS---SGSSMSSSQNQHGSSKGKSPSRNKKPSLTAVIDKLK 1311
Query: 464 SLTLTGGPDGSPHPDPSAGAKPCGSS 489
+T GP G D G SS
Sbjct: 1312 HGVVTSGPGGEDPLDGQMGVSTNSSS 1337
Score = 61.2 bits (147), Expect = 2e-09
Identities = 118/423 (27%), Positives = 161/423 (38%), Gaps = 78/423 (18%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSL 125
SS+S +SSGS SS S S SSS S+ G S G+ S++S S S
Sbjct: 1078 SSHSQYTSSGSVSSSGSKSHHSHSSSSSSSASTSGKMKSSKSEGSSSSKLSSSMYSS--- 1134
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRG 185
QG+SGSSQ +SS G GS + SS SSS + G S+L
Sbjct: 1135 QGSSGSSQSKNSSQSGGKPGSSPITKHGLSSGSSSTKMKPQ----GKPSSL--------- 1181
Query: 186 ILNP--SQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSS 243
+NP S+P S S S+ G S ++S +P P S PI S SG S
Sbjct: 1182 -MNPSLSKPNISPSHSRPPGGS---DKLASPMKPVPGTPPSSKAK-SPISSGSGGSHMSG 1236
Query: 244 HSVSGGQRPVVVVVDQHGSGAPGVV--QGPPCSNGGLPGKPC-----PPITSVDKSYGGY 296
S S G + G G+ G + + PP SN ++S +G
Sbjct: 1237 TSSSSGMK------SSSGLGSSGSLSQKTPPSSNSCTASSSSFSSSGSSMSSSQNQHGSS 1290
Query: 297 EVVGGSSDSYLVPGMTYSKGKIYPVGYFTK----ENPVKGSPGVPSFAAGPPIS------ 346
+ G S P +T K+ G T E+P+ G GV + ++ P+S
Sbjct: 1291 K--GKSPSRNKKPSLTAVIDKL-KHGVVTSGPGGEDPLDGQMGVSTNSSSHPMSSKHNMS 1347
Query: 347 ----EGKYFSSNPIIPSQSAASSAI-------AFQPVGTGGVQLC-----GGGSTGSK-- 388
+GK S+ S + S++ + VG+ GV GGS K
Sbjct: 1348 GGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAK 1407
Query: 389 ------GPCSPSSSRVPSSSSISSSSGL-----PYHPCGSASQSPCSPPGTGSFSSSSSS 437
G S R +SS + S L P H GS S S + S S S
Sbjct: 1408 VTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHERGSPSHSKSPAYTPQNLDSESES 1467
Query: 438 QSS 440
SS
Sbjct: 1468 GSS 1470
Score = 49.3 bits (116), Expect = 9e-06
Identities = 79/321 (24%), Positives = 118/321 (36%), Gaps = 42/321 (13%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS-SARSSGGGSSGSSSGSSI 97
S P ++ SP P + G SS S S S GS +S ++ SSG SSSG
Sbjct: 1196 SRPPGGSDKLASPMKP-VPGTPPSSKAKSPISSGSGGSHMSGTSSSSG---MKSSSGL-- 1249
Query: 98 AQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSS 157
GS+GS T S S S + SS +SGSS S + H S G + S +
Sbjct: 1250 ---GSSGSLSQKTPPS--SNSCTASSSSFSSSGSSMSSSQNQHGSSKGKSPSRNKKPSLT 1304
Query: 158 SSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
+ + G G P + G+ S SS G G+ S++
Sbjct: 1305 AVIDKLKHGVVTSGPGGEDPL--DGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDK 1362
Query: 218 CSSDIPDSPCSGGPIVSHSGPYIPSSHSVS-----GGQRPVVVVVDQHGSGAPGV----- 267
VS SG + SS S G +++ +H G+P +
Sbjct: 1363 SK-------------VSTSGSSVDSSKKTSESKNVGSTGVAKIIISKHDGGSPSIKAKVT 1409
Query: 268 VQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKE 327
+Q P G G+ P + K+YG ++ GS+ + ++SK Y E
Sbjct: 1410 LQKP----GESSGEGLRPQMASSKNYGS-PLISGSTPKHERGSPSHSKSPAYTPQNLDSE 1464
Query: 328 NPVKGSPGVPSFAAGPPISEG 348
+ S S+ P +G
Sbjct: 1465 SESGSSIAEKSYQNSPSSDDG 1485
Score = 37.4 bits (85), Expect = 0.034
Identities = 40/163 (24%), Positives = 59/163 (36%), Gaps = 5/163 (3%)
Query: 27 LPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGG 86
L G + S + S P ++ K D + SS SS ++ S
Sbjct: 1325 LDGQMGVSTNSSSHPMSSKHNMSGGEFQGKREKSDKDKSKVSTSGSSVDSSKKTSESKNV 1384
Query: 87 GSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQ-----LGSSSSHS 141
GS+G + G + S K + SSG G Q AS + GS+ H
Sbjct: 1385 GSTGVAKIIISKHDGGSPSIKAKVTLQKPGESSGEGLRPQMASSKNYGSPLISGSTPKHE 1444
Query: 142 GSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR 184
S SHS S + + S S SS + P++D+ R
Sbjct: 1445 RGSPSHSKSPAYTPQNLDSESESGSSIAEKSYQNSPSSDDGIR 1487
>gi|33946327 nucleoporin 214kDa [Homo sapiens]
Length = 2090
Score = 62.0 bits (149), Expect = 1e-09
Identities = 114/432 (26%), Positives = 167/432 (38%), Gaps = 67/432 (15%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
T+P+ + G+ +S S G + ++ ++A + SSG SS A G +A
Sbjct: 1666 TAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSP---AFGTTAPGVFG 1722
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLG----------SSSSHSGSSGSHSGSSSSHSSSS 158
T + Q S S SS SQ G +SS+ + +SGS G++SS +SSS
Sbjct: 1723 QTTFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASS-TSSS 1781
Query: 159 SSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPC 218
SSF F SS G G +N ++ GQS Q G S G + ++
Sbjct: 1782 SSFSFGQSSPNTGGGLFGQSNAPAF---------GQSPGFGQ--GGSVFGGTSAATTTAA 1830
Query: 219 SSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSN--- 275
+S SG S++G + S G +V Q S + G V G +
Sbjct: 1831 TSGFSFCQASGFG-SSNTGSVFGQAASTGG------IVFGQQSSSSSGSVFGSGNTGRGG 1883
Query: 276 ---GGLPGKPCP------PITSVDKSYGGYEV-----VGGSSDSYLVPGMTYSK-GKIYP 320
GL GKP P +S +G + G+S + G S G+ P
Sbjct: 1884 GFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKP 1943
Query: 321 VGYFTKENPVKGSPG--------VPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAF-QP 371
G F+ S G F A P F +P A SA AF P
Sbjct: 1944 TGTFSSGGGSVASQGFGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSP 2003
Query: 372 VGTGGVQLCGGGSTGSK--GPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTG 429
+G+ G ++ G G+ + G SSS S +++S + + GS SQ G G
Sbjct: 2004 LGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQNAPTF---GSLSQ---QTSGFG 2057
Query: 430 SFSSSSSSQSSG 441
+ SS S SG
Sbjct: 2058 TQSSGFSGFGSG 2069
Score = 52.8 bits (125), Expect = 8e-07
Identities = 77/281 (27%), Positives = 109/281 (38%), Gaps = 42/281 (14%)
Query: 34 SIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS 93
S+ F P TS G G +S + SSSS S S+ ++GGG G S+
Sbjct: 1752 SVPAFGQPASSTPTSTS---------GSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSN 1802
Query: 94 GSSIAQG---GSAGSFKPGTGYSQVSYSSGSGSSLQGAS-GSSQLGSSSSHSGSSGSHSG 149
+ Q G GS GT + + ++ S Q + GSS GS + S+G
Sbjct: 1803 APAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVF 1862
Query: 150 SSSSHSSSSSSFQFSSSSFQVGNGSAL---PTNDNSYRGILNPSQPG----QSSSSSQTF 202
S SSS S F ++ G S L P+ D + + + + G +S++S F
Sbjct: 1863 GQQSSSSSGSVFGSGNTGRGGGFFSGLGGKPSQDAANKNPFSSASGGFGSTATSNTSNLF 1922
Query: 203 GVSSS------GQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSG-GQRPVVV 255
G S + S Q+P + SGG V+ G S + G G PV
Sbjct: 1923 GNSGAKTFGGFASSSFGEQKPTGTF-----SSGGGSVASQGFGFSSPNKTGGFGAAPVF- 1976
Query: 256 VVDQHGSGAPGVVQGPPCSNGGLPG-KPCPPITSVDKSYGG 295
G+P G P GG+P P TS S GG
Sbjct: 1977 -------GSPPTFGGSP-GFGGVPAFGSAPAFTSPLGSTGG 2009
Score = 50.1 bits (118), Expect = 5e-06
Identities = 125/546 (22%), Positives = 194/546 (35%), Gaps = 85/546 (15%)
Query: 22 LAGLLLPGTLA-KSIGTFS-------DPCKDPTRITSPNDPCLTGKGDSSGFSS------ 67
L LL P +LA +++G+FS D PT S T +SG S
Sbjct: 1317 LGELLFPSSLAGETLGSFSGLRVGQADDSTKPTNKASSTSLTSTQPTKTSGVPSGFNFTA 1376
Query: 68 --YSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSL 125
G + SSA ++ ++S SS A GS P T S G+SL
Sbjct: 1377 PPVLGKHTEPPVTSSATTTSVAPPAATSTSSTAVFGSL----PVTSAGSSGVISFGGTSL 1432
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGS--ALP-----T 178
S GS ++S S +++ + +SF S + + + +LP +
Sbjct: 1433 SAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLSFGSLLSSATTPSLPMSAGRS 1492
Query: 179 NDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP--CSSDIPDSPCSGGPIVSHS 236
+ + L P +PG S S+ + QS Q P S + P P VS+S
Sbjct: 1493 TEEATSSAL-PEKPGDSEVSASAASLLEEQQSAQLPQAPPQTSDSVKKEPVLAQPAVSNS 1551
Query: 237 GPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGY 296
G S+ V+ + V PP S+ +PG+ ++ S G
Sbjct: 1552 GTAASSTSLVALSAEATPATTGVPDARTEAV---PPASSFSVPGQTAVTAAAIS-SAGPV 1607
Query: 297 EV------VGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAG-------- 342
V + S+ S + PG + G T + V P S ++
Sbjct: 1608 AVETSSTPIASSTTSIVAPGPSAEAAAF---GTVTSGSSVFAQPPAASSSSAFNQLTNNT 1664
Query: 343 ------PPISEGKYFSSNPIIPSQ---SAASSAIAFQPVGTGGVQLCGGGST--GSKGPC 391
P+ S+ P + Q S AS+A A V + G G+T G G
Sbjct: 1665 ATAPSATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAFGTTAPGVFGQT 1724
Query: 392 SPSSSRVPSSSSISSSSGLPYHPCG---------SASQSPCSPPGT----GSFSSSSSSQ 438
+ + V S+ S++S + G AS +P S G+ S +SSSSS
Sbjct: 1725 TFGQASVFGQSASSAASVFSFSQPGFSSVPAFGQPASSTPTSTSGSVFGAASSTSSSSSF 1784
Query: 439 SSGKIILQPCGSKSSSSGHPCMSVS-----SLTLTGGPDGSPHPDPSAGAKPC-----GS 488
S G+ G S P S ++ GG + ++G C GS
Sbjct: 1785 SFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFGGTSAATTTAATSGFSFCQASGFGS 1844
Query: 489 SSAGKI 494
S+ G +
Sbjct: 1845 SNTGSV 1850
Score = 47.4 bits (111), Expect = 3e-05
Identities = 96/395 (24%), Positives = 157/395 (39%), Gaps = 74/395 (18%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGS-SSGSSI-AQGGSAGSFKPGTGYSQVSYSSGSGS 123
SS +SS+ S ++ S+ + G+ +SGSS+ AQ +A S + ++Q++ ++ +
Sbjct: 1612 SSTPIASSTTSIVAPGPSAEAAAFGTVTSGSSVFAQPPAASS---SSAFNQLTNNTATAP 1668
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
S G ++ S G + S+++ + SS FSS +F G+ P
Sbjct: 1669 SATPVFGQVAASTAPSLFGQQTGSTASTAAATPQVSSSGFSSPAF----GTTAP------ 1718
Query: 184 RGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIP--DSPCSGGPIVSHSGPYIP 241
G+ + GQ+S Q+ +SS SV S +P S +P P S P S SG
Sbjct: 1719 -GVFGQTTFGQASVFGQS---ASSAASVFSFSQPGFSSVPAFGQPASSTP-TSTSGSVFG 1773
Query: 242 SSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG-GYEVVG 300
++ S S S + Q P + GGL G+ P +G G V G
Sbjct: 1774 AASSTSS-------------SSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVFG 1820
Query: 301 GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ 360
G+S + + G+ + GS S + G F Q
Sbjct: 1821 GTSAATTTAATS---------GFSFCQASGFGSSNTGSVFGQAASTGGIVFGQ------Q 1865
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ 420
S++SS F G+G GG +G G S ++ + + SS+SG
Sbjct: 1866 SSSSSGSVF---GSGNTGRGGGFFSGLGGKPSQDAA---NKNPFSSASG----------- 1908
Query: 421 SPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSS 455
G GS ++S++S G + G +SSS
Sbjct: 1909 ------GFGSTATSNTSNLFGNSGAKTFGGFASSS 1937
Score = 46.6 bits (109), Expect = 6e-05
Identities = 104/439 (23%), Positives = 157/439 (35%), Gaps = 61/439 (13%)
Query: 99 QGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSS 158
QG S KP S + +SG SS ASG++++ ++ + + S+ S S S
Sbjct: 1165 QGSLINSLKP----SGPTPASGQLSSGDKASGTAKIETAVTSTPSASGQFSKPFSFSPSG 1220
Query: 159 SSFQFS------SSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVS 212
+ F F SS+F G+ T ++ SQP SS G S +++
Sbjct: 1221 TGFNFGIITPTPSSNFTAAQGATPSTKES--------SQPDAFSSGG---GSKPSYEAIP 1269
Query: 213 SNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPP 272
+ P + G P S S P PS ++ S ++ PP
Sbjct: 1270 ESSPPSGITSASNTTPGEPAASSSRPVAPSGTAL---------------STTSSKLETPP 1314
Query: 273 CSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKG 332
G L P S+ G V G +D P S + T P K
Sbjct: 1315 SKLGELL-FPSSLAGETLGSFSGLRV--GQADDSTKPTNKASSTSL------TSTQPTKT 1365
Query: 333 SPGVPS---FAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKG 389
S GVPS F A P + GK+ + P + S + +S T + G S G
Sbjct: 1366 S-GVPSGFNFTAPPVL--GKH--TEPPVTSSATTTSVAPPAATSTSSTAVFGSLPVTSAG 1420
Query: 390 PCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCG 449
SS V S S S+G GS + PP +++++ + L G
Sbjct: 1421 -----SSGVISFGGTSLSAGKTSFSFGSQQTNSTVPPSAPPPTTAATPLPTSFPTLS-FG 1474
Query: 450 SKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRSIRDILAQVKPL 509
S SS+ P + +S+ T S P+ ++ S+SA + L Q P
Sbjct: 1475 SLLSSATTPSLPMSAGRSTEEATSSALPEKPGDSEV--SASAASLLEEQQSAQLPQAPPQ 1532
Query: 510 GPQLADPEVFLPQGELLNS 528
E L Q + NS
Sbjct: 1533 TSDSVKKEPVLAQPAVSNS 1551
Score = 45.4 bits (106), Expect = 1e-04
Identities = 68/264 (25%), Positives = 106/264 (40%), Gaps = 40/264 (15%)
Query: 41 PCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSIS-SARSSGGGSSGSSSGSSIAQ 99
P PT TS P ++ +S SS + + S +GG + S GSS +
Sbjct: 431 PGSTPTTPTSSQAPQKLDASAAAAPASLPPSSPAAPIATFSLLPAGGAPTVFSFGSSSLK 490
Query: 100 GGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSS 159
+ + +P SYSSGS SS S S +S + + ++S + S++
Sbjct: 491 SSATVTGEPP------SYSSGSDSSKAAPGPGPSTFSFVPPSKASLAPTPAASPVAPSAA 544
Query: 160 SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSS----SSSQTFGVSSSGQSVSSNQ 215
SF F SS F+ S + ++ + PS P +S + S+ F +++ VSS+Q
Sbjct: 545 SFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLSEKFTAAATSTPVSSSQ 604
Query: 216 -----RPCSSDIPDSPCSGGPIVSHSGPY---------------IPSSHSVSGGQRPVVV 255
P SS P + GP+ SH P PS S G PV
Sbjct: 605 SAPPMSPFSS--ASKPAASGPL-SHPTPLSAPPSSVPLKSSVLPSPSGRSAQGSSSPVPS 661
Query: 256 VVDQHGSGAPGVVQGPPCSNGGLP 279
+V + +P + PP + G P
Sbjct: 662 MVQK----SPRIT--PPAAKPGSP 679
Score = 45.1 bits (105), Expect = 2e-04
Identities = 83/335 (24%), Positives = 126/335 (37%), Gaps = 30/335 (8%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGG------SAGSFKPGTGYSQ---VS 116
+S + +S+SGS +A S+ SS S SS GG +A +F G+ Q V
Sbjct: 1760 ASSTPTSTSGSVFGAASSTSSSSSFSFGQSSPNTGGGLFGQSNAPAFGQSPGFGQGGSVF 1819
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176
+ + ++ SG S +S S ++GS G ++S Q SSSS V
Sbjct: 1820 GGTSAATTTAATSGFSFCQASGFGSSNTGSVFGQAASTGGIVFGQQSSSSSGSVFGSGNT 1879
Query: 177 PTNDNSYRGILNPSQPGQSSSSSQTFGVSSS--GQSVSSNQRPCSSDIPDSPCSGGPIVS 234
+ G+ +P Q +++ F +S G + +SN + + GG S
Sbjct: 1880 GRGGGFFSGL--GGKPSQDAANKNPFSSASGGFGSTATSNTSNLFGN-SGAKTFGGFASS 1936
Query: 235 HSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
G P+ SGG V G +P G G P PP +G
Sbjct: 1937 SFGEQKPTGTFSSGGGS---VASQGFGFSSPNKTGG----FGAAPVFGSPPTFGGSPGFG 1989
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSN 354
G GS+ ++ P + + GK++ G + G ++ S G S N
Sbjct: 1990 GVPAF-GSAPAFTSP-LGSTGGKVFGEG-----TAAASAGGFGFGSSSNTTSFGTLASQN 2042
Query: 355 -PIIPSQSAASSAIAFQPVGTGGV-QLCGGGSTGS 387
P S S +S Q G G GG S GS
Sbjct: 2043 APTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGS 2077
Score = 35.4 bits (80), Expect = 0.13
Identities = 29/98 (29%), Positives = 42/98 (42%), Gaps = 4/98 (4%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGY----SQV 115
G S GF S+ + S S+GG G + ++ A G GS T + SQ
Sbjct: 1983 GGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEGTAAASAGGFGFGSSSNTTSFGTLASQN 2042
Query: 116 SYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSS 153
+ + GS S G+ G S SG+ G GS++S
Sbjct: 2043 APTFGSLSQQTSGFGTQSSGFSGFGSGTGGFSFGSNNS 2080
Score = 35.0 bits (79), Expect = 0.17
Identities = 49/193 (25%), Positives = 76/193 (39%), Gaps = 33/193 (17%)
Query: 3 SSRAPWMGRVGGHGMMALLLAGLLLPGTLAKSIGTFSDPC---KDPTRITSPNDPCLTGK 59
+++ P+ GG G A L + AK+ G F+ + PT S + +
Sbjct: 1898 ANKNPFSSASGGFGSTATSNTSNLFGNSGAKTFGGFASSSFGEQKPTGTFSSGGGSVASQ 1957
Query: 60 GDSSGFSSYSGSSSSGSS--ISSARSSGG----------GSS-------GSSSGSSIAQG 100
G GFSS + + G++ S + GG GS+ GS+ G +G
Sbjct: 1958 G--FGFSSPNKTGGFGAAPVFGSPPTFGGSPGFGGVPAFGSAPAFTSPLGSTGGKVFGEG 2015
Query: 101 ---GSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSS 157
SAG F G G S + S G+ +S + GS S + G+ S S S
Sbjct: 2016 TAAASAGGF--GFGSSSNTTSFGTLAS----QNAPTFGSLSQQTSGFGTQSSGFSGFGSG 2069
Query: 158 SSSFQFSSSSFQV 170
+ F F S++ V
Sbjct: 2070 TGGFSFGSNNSSV 2082
Score = 31.2 bits (69), Expect = 2.5
Identities = 44/213 (20%), Positives = 68/213 (31%), Gaps = 19/213 (8%)
Query: 329 PVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSA--------IAFQPVGTGGVQLC 380
P G+P V SF + S P S S +S A +F P +
Sbjct: 474 PAGGAPTVFSFGSSSLKSSATVTGEPPSYSSGSDSSKAAPGPGPSTFSFVPPSKASL--- 530
Query: 381 GGGSTGSKGPCSPSSSRVPSSSS----ISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSS 436
T + P +PS++ SS S+ +P + + P PP T + + S
Sbjct: 531 --APTPAASPVAPSAASFSFGSSGFKPTLESTPVPSVSAPNIAMKPSFPPSTSAVKVNLS 588
Query: 437 SQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPC 496
+ + P S S+ S +S GP HP P + + +P
Sbjct: 589 EKFTAAATSTPVSSSQSAPPMSPFSSASKPAASGP--LSHPTPLSAPPSSVPLKSSVLPS 646
Query: 497 RSIRDILAQVKPLGPQLADPEVFLPQGELLNSP 529
S R P+ + P SP
Sbjct: 647 PSGRSAQGSSSPVPSMVQKSPRITPPAAKPGSP 679
>gi|119395750 keratin 1 [Homo sapiens]
Length = 644
Score = 61.6 bits (148), Expect = 2e-09
Identities = 47/119 (39%), Positives = 55/119 (46%), Gaps = 9/119 (7%)
Query: 58 GKGDSSGFSSYS------GSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTG 111
G G SG SSY GS G + SGG S GS GS + GG G G+G
Sbjct: 522 GGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYGSG 581
Query: 112 YSQVSYSSGSGSSLQGASG--SSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
S Y GSG G+SG S GSS G GS SG S S SSS +F S+++
Sbjct: 582 SSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKS-SGGSSSVKFVSTTY 639
Score = 54.7 bits (130), Expect = 2e-07
Identities = 51/141 (36%), Positives = 61/141 (43%), Gaps = 15/141 (10%)
Query: 72 SSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGS 131
S+S ++IS S GGG G SG S + G GS+ G G S GSG S G+ G
Sbjct: 506 STSHTTISGGGSRGGGGGGYGSGGS-SYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGG 564
Query: 132 SQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQ 191
S SG G S+ S SSS + S G GS+ S G S
Sbjct: 565 SY---------GSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSS--GGRGSGGGSSGGSI 613
Query: 192 PGQSSSSSQTFGVSSSGQSVS 212
G+ SSS GV SSG S S
Sbjct: 614 GGRGSSSG---GVKSSGGSSS 631
Score = 52.4 bits (124), Expect = 1e-06
Identities = 44/115 (38%), Positives = 48/115 (41%), Gaps = 10/115 (8%)
Query: 63 SGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSG 122
SG S G S S+ SGGGS GS G GG GS+ G+G S SY SG G
Sbjct: 513 SGGGSRGGGGGGYGSGGSSYGSGGGSYGSGGGG----GGGRGSY--GSGGS--SYGSGGG 564
Query: 123 S--SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
S S G G GS SS G G G S S SS G GS+
Sbjct: 565 SYGSGGGGGGHGSYGSGSSSGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS 619
Score = 38.9 bits (89), Expect = 0.012
Identities = 28/66 (42%), Positives = 31/66 (46%), Gaps = 8/66 (12%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSG-------SSSGSSIAQGGSAGSFKPGT 110
G G SSG GS G S R SGGGSSG SSSG + GGS+ T
Sbjct: 579 GSGSSSG-GYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSSSGGVKSSGGSSSVKFVST 637
Query: 111 GYSQVS 116
YS V+
Sbjct: 638 TYSGVT 643
Score = 37.4 bits (85), Expect = 0.034
Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 14/93 (15%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+G G SSG + +S S+ RS GGG SS GG GSF G G+
Sbjct: 13 SGGGFSSGSAGIINYQRRTTSSSTRRSGGGGGRFSSC------GGGGGSFGAGGGF---- 62
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
SL GS + S + G GS G
Sbjct: 63 ----GSRSLVNLGGSKSISISVARGGGRGSGFG 91
Score = 32.7 bits (73), Expect = 0.84
Identities = 27/90 (30%), Positives = 30/90 (33%), Gaps = 4/90 (4%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
G GF S S + GS S + GG GS G GG G G G+
Sbjct: 57 GAGGGFGSRSLVNLGGSKSISISVARGGGRGSGFGGGYGGGGFGGGGFGGGGFG----GG 112
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
G G G GS G G G G
Sbjct: 113 GIGGGGFGGFGSGGGGFGGGGFGGGGYGGG 142
Score = 31.6 bits (70), Expect = 1.9
Identities = 21/66 (31%), Positives = 23/66 (34%), Gaps = 5/66 (7%)
Query: 58 GKGDSSGF-SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
G G SGF Y G G GGG G G + GG G G G+
Sbjct: 83 GGGRGSGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFG----GGGFGGGG 138
Query: 117 YSSGSG 122
Y G G
Sbjct: 139 YGGGYG 144
Score = 31.6 bits (70), Expect = 1.9
Identities = 19/64 (29%), Positives = 21/64 (32%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+G G G + G G GGG G SG GG G G GY V
Sbjct: 88 SGFGGGYGGGGFGGGGFGGGGFGGGGIGGGGFGGFGSGGGGFGGGGFGGGGYGGGYGPVC 147
Query: 117 YSSG 120
G
Sbjct: 148 PPGG 151
Score = 31.2 bits (69), Expect = 2.5
Identities = 39/121 (32%), Positives = 42/121 (34%), Gaps = 7/121 (5%)
Query: 373 GTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFS 432
G GG GG S GS G S S G Y G + S G GS+
Sbjct: 520 GGGGGYGSGGSSYGSGGGSYGSGGGGGGGRGSYGSGGSSYGSGGGSYGSGGGGGGHGSYG 579
Query: 433 SSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAG 492
S SS S G G SS G SS GG S S G K G SS+
Sbjct: 580 SGSS--SGGYRGGSGGGGGGSSGGRGSGGGSSGGSIGGRGSS-----SGGVKSSGGSSSV 632
Query: 493 K 493
K
Sbjct: 633 K 633
>gi|18375613 dachshund homolog 1 isoform b [Homo sapiens]
Length = 558
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/156 (31%), Positives = 66/156 (42%), Gaps = 29/156 (18%)
Query: 45 PTRITSPNDPCLTGKGDSSGFSSYSGSSSS------------------------GSSISS 80
PT++ P P T S +S S ++SS ++ ++
Sbjct: 10 PTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAAT 69
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ-----VSYSSGSGSSLQGASGSSQLG 135
S+GGG G SG G+ G G G S + S+GSG G S +
Sbjct: 70 VTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129
Query: 136 SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
SS+ + S+GS S SSSS SSSSSS SSSS G
Sbjct: 130 SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCG 165
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/133 (33%), Positives = 60/133 (45%), Gaps = 18/133 (13%)
Query: 337 PSFAAGPPISEGK-YFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP----- 390
P+ + GPP S G F PI + +AA++ + G GG GGGS+G+ G
Sbjct: 40 PAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGG 99
Query: 391 ----CSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQ 446
C+P+ + ++S+ S G G + S TGS SSSSSS SS
Sbjct: 100 GGSNCNPN---LAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS---- 152
Query: 447 PCGSKSSSSGHPC 459
S SSSS C
Sbjct: 153 -SSSSSSSSSSSC 164
>gi|18375611 dachshund homolog 1 isoform a [Homo sapiens]
Length = 706
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/156 (31%), Positives = 66/156 (42%), Gaps = 29/156 (18%)
Query: 45 PTRITSPNDPCLTGKGDSSGFSSYSGSSSS------------------------GSSISS 80
PT++ P P T S +S S ++SS ++ ++
Sbjct: 10 PTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAAT 69
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ-----VSYSSGSGSSLQGASGSSQLG 135
S+GGG G SG G+ G G G S + S+GSG G S +
Sbjct: 70 VTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129
Query: 136 SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
SS+ + S+GS S SSSS SSSSSS SSSS G
Sbjct: 130 SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCG 165
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/133 (33%), Positives = 60/133 (45%), Gaps = 18/133 (13%)
Query: 337 PSFAAGPPISEGK-YFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP----- 390
P+ + GPP S G F PI + +AA++ + G GG GGGS+G+ G
Sbjct: 40 PAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGG 99
Query: 391 ----CSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQ 446
C+P+ + ++S+ S G G + S TGS SSSSSS SS
Sbjct: 100 GGSNCNPN---LAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS---- 152
Query: 447 PCGSKSSSSGHPC 459
S SSSS C
Sbjct: 153 -SSSSSSSSSSSC 164
>gi|18375609 dachshund homolog 1 isoform c [Homo sapiens]
Length = 504
Score = 61.6 bits (148), Expect = 2e-09
Identities = 49/156 (31%), Positives = 66/156 (42%), Gaps = 29/156 (18%)
Query: 45 PTRITSPNDPCLTGKGDSSGFSSYSGSSSS------------------------GSSISS 80
PT++ P P T S +S S ++SS ++ ++
Sbjct: 10 PTQLVPPQPPISTSASSSGTTTSTSSATSSPAPSIGPPASSGPTLFRPEPIASAAAAAAT 69
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQ-----VSYSSGSGSSLQGASGSSQLG 135
S+GGG G SG G+ G G G S + S+GSG G S +
Sbjct: 70 VTSTGGGGGGGGSGGGGGSSGNGGGGGGGGGGSNCNPNLAAASNGSGGGGGGISAGGGVA 129
Query: 136 SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
SS+ + S+GS S SSSS SSSSSS SSSS G
Sbjct: 130 SSTPINASTGSSSSSSSSSSSSSSSSSSSSSSSSCG 165
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/133 (33%), Positives = 60/133 (45%), Gaps = 18/133 (13%)
Query: 337 PSFAAGPPISEGK-YFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP----- 390
P+ + GPP S G F PI + +AA++ + G GG GGGS+G+ G
Sbjct: 40 PAPSIGPPASSGPTLFRPEPIASAAAAAATVTSTGGGGGGGGSGGGGGSSGNGGGGGGGG 99
Query: 391 ----CSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQ 446
C+P+ + ++S+ S G G + S TGS SSSSSS SS
Sbjct: 100 GGSNCNPN---LAAASNGSGGGGGGISAGGGVASSTPINASTGSSSSSSSSSSSSS---- 152
Query: 447 PCGSKSSSSGHPC 459
S SSSS C
Sbjct: 153 -SSSSSSSSSSSC 164
>gi|239508976 PREDICTED: mucin 12, cell surface associated [Homo
sapiens]
Length = 2036
Score = 61.2 bits (147), Expect = 2e-09
Identities = 98/412 (23%), Positives = 157/412 (38%), Gaps = 38/412 (9%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
+S+ F S SGS+ G+ +S ARS+ G G S+ S ++ + + PG+ S
Sbjct: 870 ESTTFPSSSGST--GTKLSPARSTTSGLVGESTPSRLSPSSTETTTLPGS--PTTPSLSE 925
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFS-SSSFQVGNGSALPTN 179
++ + S S + + SSG SS+SHS S+ + S + S PT
Sbjct: 926 KSTTFYTSPRSPDATLSPATTTSSGVSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTT 985
Query: 180 DNSYRGILNPS-QPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIVSH 235
+S +G + PG +++S S QS + + P ++ +PD + G +V
Sbjct: 986 SHSSQGSTEATLSPGSTTAS------SLGQQSTTFHSSPGDTETTLLPDDTITSG-LVEA 1038
Query: 236 SGPYIPSSHSVSGGQRPVVVVVDQHGSG---APGVVQGPPCSNGGLPGKPCPPITSVDKS 292
S P +HS +G + +G Q P S+ P P V+ S
Sbjct: 1039 STP----THSSTGSLHTTLTPASSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVS 1094
Query: 293 YGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFS 352
+ + ++ T +G + V SPG A P S
Sbjct: 1095 TTYHSRPSSTPTTHFSASST-------TLGRSEESTTVHSSPGATGTALFPTRSATSVLV 1147
Query: 353 SNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVP---SSSSISSSSG 409
P S+ S+ P T L +T P SP ++ P +SS +S S
Sbjct: 1148 GEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSPASTTSSGVSEEST 1207
Query: 410 LPYHPCGS----ASQSPCSPPGTGSFSSSS-SSQSSGKIILQPCGSKSSSSG 456
+ GS A + PG S++S SS S L P + +SS G
Sbjct: 1208 TSHSRPGSTHTTAFPGSTTMPGVSQESTASHSSPGSTDTTLSPGSTTASSLG 1259
Score = 53.5 bits (127), Expect = 5e-07
Identities = 105/475 (22%), Positives = 179/475 (37%), Gaps = 63/475 (13%)
Query: 30 TLAKSIGTFSDPCKDPTRI-TSPNDPCLTGKGDSSGFS--------SYSGSSSSGSSISS 80
T++ + T S ++PT +SP T DSS S S+S ++G+ +
Sbjct: 354 TISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSGRSEESTASHSSQDATGTIVLP 413
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGT----GYSQVS-----------------YSS 119
ARS+ G S+ S I+ G + PG+ G S+ S ++
Sbjct: 414 ARSTTSVLLGESTTSPISSGSMETTALPGSTTTPGLSERSTTFHSSPRSPATTLSPASTT 473
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
SG S + + S+ GS+ + + + + S HS++S S S+ + + ++ T+
Sbjct: 474 SSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHSTTSHSSPGSTDTTLL--PASTTTS 531
Query: 180 DNSYRGILNPSQPGQSS---SSSQTFGVSSSGQSVSSNQRPCSSD---IPDSPCSGGPIV 233
S + S G + S T +S +S + + P S+ PDS S G +
Sbjct: 532 GPSQESTTSHSSSGSTDTALSPGSTTALSFGQESTTFHSNPGSTHTTLFPDSTTSSGIVE 591
Query: 234 SHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG---VVQGPPCSNGGLPGKPCPPITSVD 290
+ + HS +G R + G G Q P S P P V+
Sbjct: 592 AST-----RVHSSTGSPRTTLSPASSTSPGLQGESTAFQTHPASTHTTPSPPSTATAPVE 646
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
+S Y GS+ + P + + G F G+ PS A G+
Sbjct: 647 ES-TTYHRSPGSTPTTHFPASSTTSGHSEKSTIFHSSPDASGT--TPSSAHSTTSGRGES 703
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSS-------SS 403
+S S S+ I P T L +T P SP+++ P+S
Sbjct: 704 TTSR-----ISPGSTEITTLPGSTTTPGLSEASTTFYSSPRSPTTTLSPASMTSLGVGEE 758
Query: 404 ISSSSGLPYHPCGSASQSPCSPPGTGSFSSS--SSSQSSGKIILQPCGSKSSSSG 456
++S P + S + + PG S++ SSS+ S + + P + +S G
Sbjct: 759 STTSRSQPGSTHSTVSPASTTTPGLSEESTTVYSSSRGSTETTVFPHSTTTSVHG 813
Score = 49.3 bits (116), Expect = 9e-06
Identities = 92/428 (21%), Positives = 151/428 (35%), Gaps = 45/428 (10%)
Query: 71 SSSSGSSISSARSSGGGSSGSSSGS-SIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGAS 129
S +S + SS RS S +S S + + + +PG+ +S VS +S + L S
Sbjct: 728 SEASTTFYSSPRSPTTTLSPASMTSLGVGEESTTSRSQPGSTHSTVSPASTTTPGLSEES 787
Query: 130 GSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNP 189
+ S S + HS ++S H ++F +S + L T D++ G+
Sbjct: 788 TTVYSSSRGSTETTVFPHSTTTSVHGEEPTTFHSRPAS----THTTLFTEDSTTSGLTEE 843
Query: 190 SQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGG 249
S S +S G+ ++ + + S+ P S S G +S P+ + SG
Sbjct: 844 STAFPGSPASTQTGLPATLTTADLGEE--STTFPSSSGSTGTKLS------PARSTTSG- 894
Query: 250 QRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP 309
G P + LPG P P S+ + + S D+ L P
Sbjct: 895 ---------LVGESTPSRLSPSSTETTTLPGSPTTP--SLSEKSTTFYTSPRSPDATLSP 943
Query: 310 GMTYSKGKIYPVGYFTKENPVKGS-PGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIA 368
T S G ++E+ S PG A P + S P S S+
Sbjct: 944 ATTTSSG-------VSEESSTSHSQPGSTHTTAFPDSTTTSDLSQEPTTSHSSQGSTEAT 996
Query: 369 FQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISS--SSGLPYHPCGSASQSPCSPP 426
P T L +T P ++ +P + S + P H + + +P
Sbjct: 997 LSPGSTTASSLGQQSTTFHSSPGDTETTLLPDDTITSGLVEASTPTHSSTGSLHTTLTPA 1056
Query: 427 GTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVS-----SLTLTGGPDGSPHPDPSA 481
SS+S+ Q S S ++ P + + S T P +P SA
Sbjct: 1057 -----SSTSAGLQEESTTFQSWPSSSDTTPSPPGTTAAPVEVSTTYHSRPSSTPTTHFSA 1111
Query: 482 GAKPCGSS 489
+ G S
Sbjct: 1112 SSTTLGRS 1119
Score = 47.0 bits (110), Expect = 4e-05
Identities = 120/536 (22%), Positives = 183/536 (34%), Gaps = 107/536 (19%)
Query: 28 PGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSG------------ 75
PG KS +S P SP+ L SSG S S +S S
Sbjct: 117 PGLSEKSTTFYSSP-------RSPDTTHLPASMTSSGVSEESTTSHSRPGSTHTTAFPGS 169
Query: 76 ------SSISSARSSGGG------SSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
S S+A S G S GS++ SS+ + +PG+ + + + + S
Sbjct: 170 TTMPGLSQESTASHSSPGPTDTTLSPGSTTASSLGPEYTTFHSRPGSTETTLLPDNTTAS 229
Query: 124 SLQGASGSSQLGSSSSH-----SGSSGSHSGSSSSHSSSSS-----------SFQFSSSS 167
L AS + S H +GS+ S++ HS SS S S+
Sbjct: 230 GLLEASMPVHSSTRSPHTTLSPAGSTTRQGESTTFHSWPSSKDTRPAPPTTTSAFVEPST 289
Query: 168 FQVGNGSALPTNDNSYR----GILNPSQPGQSS-SSSQTF------GVSSSGQSVSSNQR 216
G+ S++PT S R G++ S SS S+QT S G+ +++
Sbjct: 290 TSHGSPSSIPTTHISARSTTSGLVEESTTYHSSPGSTQTMHFPESDTTSGRGEESTTSHS 349
Query: 217 PCSSDIPDSPCSGGPIVS-----HSGP------YIPSSHSVSGGQRPVVVVVDQHGSGAP 265
+ I +P + +V HS P + P S + SG R A
Sbjct: 350 STTHTISSAPSTTSALVEEPTSYHSSPGSTATTHFPDSSTTSG--RSEESTASHSSQDAT 407
Query: 266 GVVQGPPCSNGG--LPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGY 323
G + P S L PI+S GS ++ +PG T + G
Sbjct: 408 GTIVLPARSTTSVLLGESTTSPISS------------GSMETTALPGSTTTP------GL 449
Query: 324 FTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGG 383
+ SP P+ P + S S+ P T L
Sbjct: 450 SERSTTFHSSPRSPATTLSPASTTSSGVSEESTTSRSRPGSTHTTAFPDSTTTPGLSRHS 509
Query: 384 STGSKGPCSPSSSRVPSSSSIS--SSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
+T P S ++ +P+S++ S S H ++ + SP GS ++ S Q S
Sbjct: 510 TTSHSSPGSTDTTLLPASTTTSGPSQESTTSHSSSGSTDTALSP---GSTTALSFGQEST 566
Query: 442 KIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGA-----KPCGSSSAG 492
P S H + S T +G + S S G+ P S+S G
Sbjct: 567 TFHSNP------GSTHTTLFPDSTTSSGIVEASTRVHSSTGSPRTTLSPASSTSPG 616
Score = 45.4 bits (106), Expect = 1e-04
Identities = 64/241 (26%), Positives = 99/241 (41%), Gaps = 41/241 (17%)
Query: 26 LLPGTLAKSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSS-----YSGSSSSGSSISS 80
L P A S+ +P P S L G ++G S YS S +++S
Sbjct: 1136 LFPTRSATSV-LVGEPTTSPISSGSTETTALPGSTTTAGLSEKSTTFYSSPRSPDTTLSP 1194
Query: 81 ARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSH 140
A ++ G S S+ S G + + PG+ +++ G S S ++SH
Sbjct: 1195 ASTTSSGVSEESTTSHSRPGSTHTTAFPGS------------TTMPGVSQES----TASH 1238
Query: 141 SGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA----LPTNDNSYRGILNPSQPGQSS 196
S S GS + S S+++SS S++F GS LP N + G+L S P SS
Sbjct: 1239 S-SPGSTDTTLSPGSTTASSLGPESTTFHSSPGSTETTLLPDNTTA-SGLLEASTPVHSS 1296
Query: 197 SSSQTFGVSSS------GQSVSSNQRPCSSD-IPDSPCSGGPIV-----SHSGP-YIPSS 243
+ S +S + G+S + P S D +P P + V SH P P++
Sbjct: 1297 TGSPHTTLSPAGSTTRQGESTTFQSWPSSKDTMPAPPTTTSAFVELSTTSHGSPSSTPTT 1356
Query: 244 H 244
H
Sbjct: 1357 H 1357
Score = 36.2 bits (82), Expect = 0.076
Identities = 43/173 (24%), Positives = 69/173 (39%), Gaps = 12/173 (6%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
T P P T +S+ SS+ ++ SA S+ G S S+ ++ A + P
Sbjct: 1328 TMPAPPTTTSAFVELSTTSHGSPSSTPTTHFSASSTTLGRSEEST--TVHSSPVATATTP 1385
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
S S ++ + GS+Q S +SG S +SHSS++ + S+
Sbjct: 1386 SPARSTTSGLVEESTAYHSSPGSTQTMHFPESSTASGRSEESRTSHSSTTHTISSPPST- 1444
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD 221
SAL SY S PG +++ ++SG+S S S D
Sbjct: 1445 ----TSALVEEPTSYH-----SSPGSIATTHFPESSTTSGRSEESTASHSSPD 1488
>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
Length = 2752
Score = 60.1 bits (144), Expect = 5e-09
Identities = 64/174 (36%), Positives = 73/174 (41%), Gaps = 29/174 (16%)
Query: 62 SSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIA------------------QGGSA 103
SS SS S SSSS SS SS+ SS G SS S GSS+ +
Sbjct: 2533 SSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVRE 2592
Query: 104 GSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQF 163
G T + SS S SS SS SSSS S SS S S SSSS SSSSSS
Sbjct: 2593 GRPPEPTPAKRKRRSSSSSSS------SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 164 SSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRP 217
SS S ALP + + PG+ S S + S S S + P
Sbjct: 2647 SSPSPAKPGPQALPKPASPKK-----PPPGERRSRSPRKPIDSLRDSRSLSYSP 2695
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/190 (32%), Positives = 76/190 (40%), Gaps = 42/190 (22%)
Query: 87 GSSGSSSGSSIAQGGSAGSFK-------PGTGYSQV-----SYSSGSGSSLQGASGSSQL 134
GS SSG+ SAG PG +S V S + S+L + +
Sbjct: 2471 GSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKER 2530
Query: 135 GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN-DNSYRGILNP---- 189
SSSS S SS S S SSSS SSSSSS SS S GS+LP + + + + +P
Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDS----EGSSLPVQPEVALKRVPSPTPAP 2586
Query: 190 ---------------------SQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCS 228
S SSSSS + SSS S SS+ SS S S
Sbjct: 2587 KEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2646
Query: 229 GGPIVSHSGP 238
P + GP
Sbjct: 2647 SSPSPAKPGP 2656
Score = 55.1 bits (131), Expect = 2e-07
Identities = 106/441 (24%), Positives = 161/441 (36%), Gaps = 79/441 (17%)
Query: 89 SGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS 148
+G+ + +++A GS P T +Y S S + Q + ++ +G S+H+ + + +
Sbjct: 2298 AGARTPAALAALSLTGSGTPPTA---ANYPSSSRTP-QAPASANLVGPRSAHATAPVNIA 2353
Query: 149 GSSSSHSSSSSSFQFSS-----------------SSFQVGNGSALPTNDNSYRGILNPSQ 191
GS ++ + + +S + S+++ +G P + R PS
Sbjct: 2354 GSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSA 2413
Query: 192 PGQSSSSSQTFGVSSS--GQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGG 249
P QS +S+ SS GQ+ S + P + D P SP S I + V+G
Sbjct: 2414 PSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSA-FSDQSRCLIAQTTPVAGS 2472
Query: 250 QRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVP 309
Q SGA + G+ P P + D
Sbjct: 2473 Q--------SLSSGAVATTTSSAGDHNGMLSVPAPGVPHSD------------------- 2505
Query: 310 GMTYSKGKIYPVGYFTKENPVKGSPGVPS-FAAGPPISEGKYFSSNPIIPSQSAASSAIA 368
VG E P PS AA P E + SS+ S S++SS+ +
Sbjct: 2506 -----------VG----EPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSS 2550
Query: 369 FQPVGTGGVQLCGGGSTGSKGPCSPSSS--RVPSSSSISSSS---GLPYHPCGSASQSPC 423
+G S GS P P + RVPS + + G P P A +
Sbjct: 2551 SSSSSSGS---SSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPT-PAKRKRR 2606
Query: 424 SPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGA 483
S + S SSSSSS SS S SSSS S SS P P P++
Sbjct: 2607 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPK 2666
Query: 484 KPCGS---SSAGKIPCRSIRD 501
KP S + + P S+RD
Sbjct: 2667 KPPPGERRSRSPRKPIDSLRD 2687
Score = 46.6 bits (109), Expect = 6e-05
Identities = 43/113 (38%), Positives = 52/113 (46%), Gaps = 2/113 (1%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
+S + + SS SS SGSSSS S SS + + A + +P
Sbjct: 2536 SSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRP 2595
Query: 109 --GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSS 159
T + SS S SS +S SS SSSS S SS S S SSSS SSSSS
Sbjct: 2596 PEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2648
Score = 43.5 bits (101), Expect = 5e-04
Identities = 27/56 (48%), Positives = 30/56 (53%)
Query: 54 PCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPG 109
P + SS SS S SSSS SS SS+ SS SS SSS SS + S KPG
Sbjct: 2600 PAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPG 2655
Score = 42.0 bits (97), Expect = 0.001
Identities = 106/459 (23%), Positives = 145/459 (31%), Gaps = 85/459 (18%)
Query: 74 SGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQ 133
S S R G SS + S +Q S + P S++S S + S+
Sbjct: 713 SHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSR 772
Query: 134 LGSSSSHSGSSG------------SHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDN 181
L S SGSS S SGSS + S + + S SS T
Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832
Query: 182 SYRGILNPSQPGQSSSSSQTFGVSS---SGQSVSSNQRPCSSDIPD----------SPCS 228
+P +S + + ++S + QSV+ +R C PD CS
Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892
Query: 229 GG--PIVSHSGPYIPSSHSVSGGQRPVVVVV-----DQHGSGAPGVVQ------------ 269
G P V S P S S Q V ++ GS +P +
Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRS 952
Query: 270 GPPCSN-------------GGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKG 316
PCSN P P T +S+ G + PG + S
Sbjct: 953 VSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGS 1012
Query: 317 KIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGG 376
K +K++ V+ PG S AG SS P P +S G
Sbjct: 1013 KSPCPQEKSKDSLVQSCPGSLSLCAGVK-------SSTP--PGESY---------FGVSS 1054
Query: 377 VQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSS 436
+QL G T SS V S S S S +S S P T S S
Sbjct: 1055 LQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPI 1114
Query: 437 SQSSGKIILQP----------CGSKSSSSGHPCMSVSSL 465
Q G+ P +S SS +P + +SL
Sbjct: 1115 RQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSL 1153
Score = 37.7 bits (86), Expect = 0.026
Identities = 38/135 (28%), Positives = 51/135 (37%), Gaps = 12/135 (8%)
Query: 384 STGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKI 443
S P S + SR+ S+S SS P Q +PP S S SSQ K
Sbjct: 759 SRSLSSPRSKAKSRLSLRRSLSGSSPCP-------KQKSQTPPRR---SRSGSSQPKAKS 808
Query: 444 ILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRSIRDIL 503
P S+SSSS P + + SPHP +G P S P + + +
Sbjct: 809 RTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS--PQANEQSVT 866
Query: 504 AQVKPLGPQLADPEV 518
Q + DPE+
Sbjct: 867 PQRRSCFESSPDPEL 881
Score = 33.9 bits (76), Expect = 0.38
Identities = 115/455 (25%), Positives = 152/455 (33%), Gaps = 84/455 (18%)
Query: 77 SISSARSSGGGSS------GSSSGSSIAQGGSAGSFKPG--TGYSQVSYSSGSGSSL--- 125
S S AR SG S G S + A+ G + S P +G S+ + G S
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRT 696
Query: 126 --QGASGSSQL---GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
+G S S L G S S + SGSSS + S + Q S S + + +
Sbjct: 697 PRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRS---NSSPEMKKSR 753
Query: 181 NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI 240
S R + S P + S + S SG S PC +P P S SG
Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSS------PCPKQKSQTP----PRRSRSGSSQ 803
Query: 241 PSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVG 300
P + S + +R S P P P P + S G +
Sbjct: 804 PKAKSRTPPRRS-----RSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQG-SITS 857
Query: 301 GSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQ 360
++ V S + P P + S + PP + SS P S
Sbjct: 858 PQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS----GSSPP----RVKSSTPPRQSP 909
Query: 361 SAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQ 420
S +SS QP + +GS SPS SRV S ++ P S S
Sbjct: 910 SRSSSP---QPKVKAIISPRQRSHSGSS---SPSPSRVTSRTT----------PRRSRSV 953
Query: 421 SPCSPPGTG-----SFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSP 475
SPCS + S S SSS + K P S S S SP
Sbjct: 954 SPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSI------------------SP 995
Query: 476 HPDPSAGAKPCGSSSAGKIPC--RSIRDILAQVKP 508
+P A P S S K PC +D L Q P
Sbjct: 996 YPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCP 1030
Score = 32.0 bits (71), Expect = 1.4
Identities = 38/139 (27%), Positives = 50/139 (35%), Gaps = 21/139 (15%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
+S + + SS SS S SSSS SS SS+ SS S ++ + S P
Sbjct: 2611 SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670
Query: 109 GTGYSQ--------------VSYS-------SGSGSSLQGASGSSQLGSSSSHSGSSGSH 147
G S+ +SYS S S S SS+ GS G S S
Sbjct: 2671 GERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSP 2730
Query: 148 SGSSSSHSSSSSSFQFSSS 166
S + S + SS
Sbjct: 2731 SHKRRRETPSPRPMRHRSS 2749
Score = 30.4 bits (67), Expect = 4.2
Identities = 32/108 (29%), Positives = 41/108 (37%), Gaps = 10/108 (9%)
Query: 53 DPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGY 112
DP L K S+ S +S S S ++ A G SS S S + P T
Sbjct: 1366 DPSLDMKEQSTRSSGHSSSELSPDAVEKA----GMSSNQSISSPVLDA------VPRTPS 1415
Query: 113 SQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSS 160
+ S S+ S G + S S S SG+ S HS S SS
Sbjct: 1416 RERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSS 1463
Score = 29.3 bits (64), Expect = 9.3
Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 20/139 (14%)
Query: 136 SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQS 195
+SSS + S S S ++ +H+++ + S +S + G G A P ++ PS P
Sbjct: 269 ASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDA-PFSEPGTTSTQRPSSP--- 324
Query: 196 SSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVV 255
+ T SS + +++ S+ P S P S +GP P+ P +
Sbjct: 325 --ETATKQPSSPYEDKDKDKKEKSATRP----SPSPERSSTGPEPPA---------PTPL 369
Query: 256 VVDQHGSGAPGVVQGPPCS 274
+ ++HG G+P + P S
Sbjct: 370 LAERHG-GSPQPLATTPLS 387
Score = 29.3 bits (64), Expect = 9.3
Identities = 41/150 (27%), Positives = 55/150 (36%), Gaps = 31/150 (20%)
Query: 369 FQPVGTGGVQLCGGGSTGSKGPCSP----------SSSRVPSSSSISSSSGLPYHPCGSA 418
F GT Q T +K P SP S+ PS S SS+G P P +
Sbjct: 310 FSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTG-PEPPAPTP 368
Query: 419 ------------------SQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCM 460
SQ P +PP S + S S + + Q S+SS P
Sbjct: 369 LLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPS-PQP 427
Query: 461 SVSSLTLTGGPDGSPHPDPSAGAKPCGSSS 490
+ S + P+ SP P P+ G+ SSS
Sbjct: 428 TKVSRHASSSPE-SPKPAPAPGSHREISSS 456
Score = 29.3 bits (64), Expect = 9.3
Identities = 38/176 (21%), Positives = 57/176 (32%), Gaps = 9/176 (5%)
Query: 34 SIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS 93
S+ PC S C +G S + S +SS + G +
Sbjct: 1008 SLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDH 1067
Query: 94 GSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGS--- 150
S + S S +S G + +S ++L S S G S S
Sbjct: 1068 RSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPML 1127
Query: 151 SSSHSSSSSSFQFSSSSFQVGNG------SALPTNDNSYRGILNPSQPGQSSSSSQ 200
S S S FQ SSS+ + S L T ++ + L P + +S Q
Sbjct: 1128 KSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQ 1183
>gi|47132620 keratin 2 [Homo sapiens]
Length = 639
Score = 59.7 bits (143), Expect = 6e-09
Identities = 49/116 (42%), Positives = 55/116 (47%), Gaps = 7/116 (6%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGG-GSSGSSSGSSIAQGG-SAGSFKPGTGYSQV 115
G+G SSG SGSSS GS + S GG G GS SG GG S G + G G
Sbjct: 523 GRGSSSGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGG 582
Query: 116 SYSS---GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
S S GSG + G S+ GSSS G GS G SSS SS SS +F
Sbjct: 583 SISGGGYGSGGGKHSSGGGSRGGSSS--GGGYGSGGGGSSSVKGSSGEAFGSSVTF 636
Score = 53.5 bits (127), Expect = 5e-07
Identities = 50/141 (35%), Positives = 59/141 (41%), Gaps = 24/141 (17%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSS-GSSIAQGGSAGSFKPGTGYSQVSYSSGSGSS 124
+++ GS GSS S GG SSGSSS GS Q GS G G S Y SG GS
Sbjct: 516 AAFGGSGGRGSS-----SGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSG 570
Query: 125 LQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYR 184
+ SG G S S S G + HSS S SSS G+G +S +
Sbjct: 571 GRYGSG----GGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGGGYGSGGG---GSSSVK 623
Query: 185 GILNPSQPGQSSSSSQTFGVS 205
G SS + FG S
Sbjct: 624 G-----------SSGEAFGSS 633
Score = 51.2 bits (121), Expect = 2e-06
Identities = 51/154 (33%), Positives = 68/154 (44%), Gaps = 21/154 (13%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY-- 117
GD S + S +SS+ SS +++++ GGS G GSS G S+GS G+G Q
Sbjct: 493 GDLSSNVTVSVTSSTISSNVASKAAFGGSGGR--GSSSGGGYSSGSSSYGSGGRQSGSRG 550
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSS---------SHSSSSSSFQFSSSSF 168
SG G S+ G S GS + GS GS S HSS S SSS
Sbjct: 551 GSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGGGYGSGGGKHSSGGGSRGGSSSGG 610
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF 202
G+G +S +G G++ SS TF
Sbjct: 611 GYGSGGG---GSSSVKG-----SSGEAFGSSVTF 636
Score = 50.4 bits (119), Expect = 4e-06
Identities = 43/110 (39%), Positives = 47/110 (42%), Gaps = 18/110 (16%)
Query: 57 TGKGDSSGFSSYS--------------GSSSSGSSISSARSSGG--GSSGSSSGSSIAQG 100
+G G SSG SSY G S SG S SGG GS G S G SI+ G
Sbjct: 528 SGGGYSSGSSSYGSGGRQSGSRGGSGGGGSISGGGYGSGGGSGGRYGSGGGSKGGSISGG 587
Query: 101 G--SAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS 148
G S G G S+ SSG G G SS GSS GSS + S
Sbjct: 588 GYGSGGGKHSSGGGSRGGSSSGGGYGSGGGGSSSVKGSSGEAFGSSVTFS 637
Score = 38.9 bits (89), Expect = 0.012
Identities = 35/107 (32%), Positives = 41/107 (38%), Gaps = 18/107 (16%)
Query: 59 KGDSSGFSSYSG----SSSSGSSISSARSSGGGSSGSSSGS------------SIAQGGS 102
+G SSG + SG S+SS S +S GGG G GS SI+ G
Sbjct: 20 RGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISISVAGG 79
Query: 103 AGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
G F G+ G GSS G SG S G G G G
Sbjct: 80 GGGFGAAGGFGGRGGGFGGGSSFGGGSGFS--GGGFGGGGFGGGRFG 124
Score = 35.8 bits (81), Expect = 0.099
Identities = 29/94 (30%), Positives = 36/94 (38%), Gaps = 3/94 (3%)
Query: 70 GSSSSGSSISSARSSGGGSSGSSSGSSIAQ-GGSAGSFKPG--TGYSQVSYSSGSGSSLQ 126
G G S SA SGG +SS S +++ GG G F G S V S+
Sbjct: 16 GGGFRGFSSGSAVVSGGSRRSTSSFSCLSRHGGGGGGFGGGGFGSRSLVGLGGTKSISIS 75
Query: 127 GASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSS 160
A G G++ G G G SS S S
Sbjct: 76 VAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFS 109
Score = 31.6 bits (70), Expect = 1.9
Identities = 31/111 (27%), Positives = 40/111 (36%), Gaps = 23/111 (20%)
Query: 81 ARSSGGGSS---GSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS----------SLQG 127
+R GGG G SSGS++ GGS S + +S +S G G SL G
Sbjct: 9 SRGRGGGGGGFRGFSSGSAVVSGGSRRS---TSSFSCLSRHGGGGGGFGGGGFGSRSLVG 65
Query: 128 ASGSSQL-------GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
G+ + G +G G G SS FS F G
Sbjct: 66 LGGTKSISISVAGGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGG 116
Score = 29.3 bits (64), Expect = 9.3
Identities = 20/65 (30%), Positives = 22/65 (33%), Gaps = 2/65 (3%)
Query: 60 GDSSGFSSYSGSSSSGSSISSARSSGGGS--SGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G GF + G G S GGGS SG G GG G F G +
Sbjct: 78 GGGGGFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGG 137
Query: 118 SSGSG 122
G G
Sbjct: 138 PGGFG 142
Score = 29.3 bits (64), Expect = 9.3
Identities = 22/69 (31%), Positives = 24/69 (34%), Gaps = 7/69 (10%)
Query: 58 GKGDSSGFSSYSGSSSSGSSI------SSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTG 111
G G + GF G GSS S GGG G G GG G PG G
Sbjct: 82 GFGAAGGFGGRGGGFGGGSSFGGGSGFSGGGFGGGGFGGGRFGGFGGPGGVGGLGGPG-G 140
Query: 112 YSQVSYSSG 120
+ Y G
Sbjct: 141 FGPGGYPGG 149
>gi|7657387 CCR4-NOT transcription complex, subunit 3 [Homo sapiens]
Length = 753
Score = 59.7 bits (143), Expect = 6e-09
Identities = 76/293 (25%), Positives = 107/293 (36%), Gaps = 36/293 (12%)
Query: 141 SGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQ 200
S S SH + SSS+ +SSS + A T +NS + + G+S+ S
Sbjct: 242 SPPSHSHMEDEIFNQSSSTPTSTTSSS-PIPPSPANCTTENSE----DDKKRGRSTDSEV 296
Query: 201 TFGVSSSGQS-VSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVV--- 256
+ + +G V SNQ P S +P + SG P + + P ++ V P +
Sbjct: 297 SQSPAKNGSKPVHSNQHPQSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPK 356
Query: 257 ---VDQHGSGAPGVVQ---GPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSY--LV 308
H SG P PP +G +P PP GG GGSS S
Sbjct: 357 ASPAPSHNSGTPAPYAQAVAPPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSA 416
Query: 309 PGMTYSKGKIYPVGYFTKENPVK------GSPGVPSFAAGPPISEGKYFSSNPIIPSQSA 362
G + ++P + G S A GPP S P P S
Sbjct: 417 GGGAGKQNGATSYSSVVADSPAEVALSSSGGNNASSQALGPP--------SGPHNPPPST 468
Query: 363 ASSAIAFQPVGTGGVQLCGGGSTGSKG-----PCSPSSSRVPSSSSISSSSGL 410
+ A P G GGV G ++G P +P SS PS S ++ L
Sbjct: 469 SKEPSAAAPTGAGGVAPGSGNNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGAL 521
Score = 47.0 bits (110), Expect = 4e-05
Identities = 42/153 (27%), Positives = 63/153 (41%), Gaps = 22/153 (14%)
Query: 69 SGSSSSGSSISSARSSGGGSSG-----SSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGS 123
SG S++ S + SGGG G SSS S+ + GG AG T YS V
Sbjct: 381 SGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSV-------- 432
Query: 124 SLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSY 183
+ + L SS ++ SS + S H+ S+ + S++ G G P + N+
Sbjct: 433 -VADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTGAGGVAPGSGNNS 491
Query: 184 RG--------ILNPSQPGQSSSSSQTFGVSSSG 208
G + PS P S S ++ G +G
Sbjct: 492 GGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNG 524
Score = 41.6 bits (96), Expect = 0.002
Identities = 42/167 (25%), Positives = 68/167 (40%), Gaps = 10/167 (5%)
Query: 333 SPGVP-SFAAGPPISEGKYFSS--NPIIPSQSAASSAIAFQ----PVGTGGVQLCGGGST 385
SP VP ++ +GPP + ++ N +P+ +A SA+ + P G +
Sbjct: 316 SPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAV 375
Query: 386 GSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIIL 445
P PS+++ S S G G +S S S G G+ + ++ S +
Sbjct: 376 APPAPSGPSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSSAGGGAGKQNGATSYSSVVAD 435
Query: 446 QPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAG 492
P SSSG S +L G P G +P PS +P ++ G
Sbjct: 436 SPAEVALSSSGGNNASSQAL---GPPSGPHNPPPSTSKEPSAAAPTG 479
Score = 40.8 bits (94), Expect = 0.003
Identities = 66/291 (22%), Positives = 106/291 (36%), Gaps = 43/291 (14%)
Query: 69 SGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGS-AGSFKPGTGYSQVSYSSGSGSSLQG 127
SG + S++S+ + G + ++ S++ S A S GT + S G
Sbjct: 325 SGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQAVAPPAPS--G 382
Query: 128 ASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGIL 187
S + S SG G SG S SSS+SS G G+ SY ++
Sbjct: 383 PSTTQPRPPSVQPSGGGGGGSGGGGSSSSSNSS---------AGGGAGKQNGATSYSSVV 433
Query: 188 --NPSQPGQSSSSSQTFGVSSSG-QSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSH 244
+P++ SSS + G S N P +S P + G +G P S
Sbjct: 434 ADSPAEVALSSSGGNNASSQALGPPSGPHNPPPSTSKEPSAAAPTG-----AGGVAPGSG 488
Query: 245 SVSGGQRPVV-VVVDQHGSGAP---------GVVQGPPCSNGGLPGKPCPPITSVDKSYG 294
+ SGG +V + V+ S P ++ GPP + K P++S+
Sbjct: 489 NNSGGPSLLVPLPVNPPSSPTPSFSDAKAAGALLNGPPQFSTAPEIKAPEPLSSLKSMAE 548
Query: 295 GYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPI 345
+ G D P + T+ + + S P +A PP+
Sbjct: 549 RAAISSGIEDP-------------VPTLHLTERDIILSSTSAPPASAQPPL 586
Score = 30.4 bits (67), Expect = 4.2
Identities = 36/134 (26%), Positives = 52/134 (38%), Gaps = 14/134 (10%)
Query: 395 SSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKS-- 452
SS P+S++ SSS +P P +++ G + S SQS K +P S
Sbjct: 257 SSSTPTSTT--SSSPIPPSPANCTTENSEDDKKRGRSTDSEVSQSPAKNGSKPVHSNQHP 314
Query: 453 -------SSSGHPCMSVSSLTLTGGPDGSPHP--DPSA-GAKPCGSSSAGKIPCRSIRDI 502
+ P + S+L+ T G +G P P PSA G K + S
Sbjct: 315 QSPAVPPTYPSGPPPAASALSTTPGNNGVPAPAAPPSALGPKASPAPSHNSGTPAPYAQA 374
Query: 503 LAQVKPLGPQLADP 516
+A P GP P
Sbjct: 375 VAPPAPSGPSTTQP 388
>gi|239755326 PREDICTED: hypothetical protein [Homo sapiens]
Length = 375
Score = 59.3 bits (142), Expect = 8e-09
Identities = 68/200 (34%), Positives = 87/200 (43%), Gaps = 21/200 (10%)
Query: 33 KSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSG-- 90
+S T S C + TS C T + S+ S S SS SS S +SSG S+
Sbjct: 124 QSSRTSSTSCSCQSSRTSSTCSCQTSRTSST---SCSYQSSRTSSTCSCQSSGTSSTSCN 180
Query: 91 --SSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHS 148
SS SS S+G+ T YS S + S S Q +SG+S S SG+S + S
Sbjct: 181 WQSSRTSSTCSCQSSGT--SSTSYSCQSSGTSSTCSCQ-SSGTSSTSCSCQSSGTSSTCS 237
Query: 149 GSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSG 208
SS SS+S S+Q S +S S+ G + S QSS +S T SSG
Sbjct: 238 CQSSGTSSTSCSWQSSRTSSTCSCQSS---------GTSSTSCSCQSSGTSSTCSCQSSG 288
Query: 209 QSVSSNQRPCSSDIPDSPCS 228
SS C S S CS
Sbjct: 289 --TSSTSCSCQSSRTSSTCS 306
Score = 55.8 bits (133), Expect = 9e-08
Identities = 66/198 (33%), Positives = 88/198 (44%), Gaps = 14/198 (7%)
Query: 33 KSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYS-GSSSSGSSISSARSSGGGSSGS 91
+S GT S C + TS C + S+ +S S G+SS+ S SS SS S S
Sbjct: 170 QSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQS 229
Query: 92 SSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS 151
S SS S+G+ T S S + S S Q +SG+S S SG+S + S S
Sbjct: 230 SGTSSTCSCQSSGT--SSTSCSWQSSRTSSTCSCQ-SSGTSSTSCSCQSSGTSSTCSCQS 286
Query: 152 SSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSV 211
S SS+S S Q S +S T + + S QSS +S T SSG S
Sbjct: 287 SGTSSTSCSCQSSRTS---------STCSCQFSRTSSTSCSCQSSRTSSTCSCQSSGTS- 336
Query: 212 SSNQRPCSSDIPDSPCSG 229
S++ SS + CSG
Sbjct: 337 STSCICWSSGTSSTSCSG 354
Score = 51.2 bits (121), Expect = 2e-06
Identities = 100/402 (24%), Positives = 143/402 (35%), Gaps = 49/402 (12%)
Query: 71 SSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASG 130
+SSS S S+++S S SS SS S+G+ T + S + S S Q +SG
Sbjct: 13 ASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGT--SSTSCNWQSSRTSSTCSCQ-SSG 69
Query: 131 SSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSS----FQVGNGSALPTNDNSYRGI 186
+S S S +S + S SS SS+S S+QFS +S Q S+ + S R
Sbjct: 70 TSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSR-T 128
Query: 187 LNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSV 246
+ S QSS +S T +S S +S S C S S + S S
Sbjct: 129 SSTSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTSCNWQSSRTSS 188
Query: 247 SGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSY 306
+ + + + G C + G C +S S + G SS S
Sbjct: 189 TCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTS- 247
Query: 307 LVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSA 366
++ + SS S +S++
Sbjct: 248 ----CSWQSSRT---------------------------------SSTCSCQSSGTSSTS 270
Query: 367 IAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSS--ISSSSGLPYHPCGSASQSPCS 424
+ Q GT C T S CS SSR S+ S S +S S + S CS
Sbjct: 271 CSCQSSGTSSTCSCQSSGTSSTS-CSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTCS 329
Query: 425 PPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLT 466
+G+ S+S SSG G S +S C SS T
Sbjct: 330 CQSSGTSSTSCICWSSGTSSTSCSGRFSGTSSTSCNCRSSGT 371
Score = 50.4 bits (119), Expect = 4e-06
Identities = 105/417 (25%), Positives = 145/417 (34%), Gaps = 75/417 (17%)
Query: 39 SDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGG---GSSGSSSGS 95
S C + TS C + + S+ SG+SS+ + S+R+S SSG+SS S
Sbjct: 15 SSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSSGTSSTS 74
Query: 96 SIAQGGSAGSF----KPGTGYSQVS--YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG 149
Q S GT + S +S S + +S +S S S +S +
Sbjct: 75 CSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSRTSSTSCS 134
Query: 150 SSSSHSSSSSSFQFS-----SSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGV 204
SS +SS+ S Q S S S+Q S+ + +S G + S QSS +S T
Sbjct: 135 CQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSS--GTSSTSCNWQSSRTSSTCSC 192
Query: 205 SSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGA 264
SSG SS C S S CS SG S S G
Sbjct: 193 QSSG--TSSTSYSCQSSGTSSTCS----CQSSGTSSTSCSCQSSGTSSTC---------- 236
Query: 265 PGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYF 324
C + G C +S S + G SS S
Sbjct: 237 -------SCQSSGTSSTSCSWQSSRTSSTCSCQSSGTSSTSCSCQ--------------- 274
Query: 325 TKENPVKGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGS 384
S G S + + SS S SS + Q T C S
Sbjct: 275 --------SSGTSSTCS----CQSSGTSSTSCSCQSSRTSSTCSCQFSRTSSTS-CSCQS 321
Query: 385 TGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSG 441
+ + CS SS S+S I SSG S + CS +G+ S+S + +SSG
Sbjct: 322 SRTSSTCSCQSSGTSSTSCICWSSG--------TSSTSCSGRFSGTSSTSCNCRSSG 370
Score = 48.9 bits (115), Expect = 1e-05
Identities = 63/203 (31%), Positives = 84/203 (41%), Gaps = 15/203 (7%)
Query: 33 KSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGS-SISSARSSGGGSSGS 91
+S GT S C TS C + + S+ S S +SS S S S+R+S S +
Sbjct: 89 QSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSRTSSTSCSCQSSRTSSTCSCQT 148
Query: 92 SSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSS 151
S SS ++ S++ S S S SG+S + S SS+ SSG+ S S
Sbjct: 149 SRTSS-----TSCSYQSSRTSSTCSCQS-SGTSSTSCNWQSSRTSSTCSCQSSGTSSTSY 202
Query: 152 SSHSSSSS------SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVS 205
S SS +S S SS+S + T G + S QSS +S T
Sbjct: 203 SCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTCSCQ 262
Query: 206 SSGQSVSSNQRPCSSDIPDSPCS 228
SSG SS C S S CS
Sbjct: 263 SSG--TSSTSCSCQSSGTSSTCS 283
Score = 45.1 bits (105), Expect = 2e-04
Identities = 41/141 (29%), Positives = 57/141 (40%), Gaps = 3/141 (2%)
Query: 352 SSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSS--SG 409
SS + +S++ ++Q T C T S C+ SSR S+ S SS S
Sbjct: 141 SSTCSCQTSRTSSTSCSYQSSRTSSTCSCQSSGTSSTS-CNWQSSRTSSTCSCQSSGTSS 199
Query: 410 LPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTG 469
Y S + S CS +G+ S+S S QSSG C S +SS S + T
Sbjct: 200 TSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTSCSWQSSRTSSTC 259
Query: 470 GPDGSPHPDPSAGAKPCGSSS 490
S S + G+SS
Sbjct: 260 SCQSSGTSSTSCSCQSSGTSS 280
Score = 39.7 bits (91), Expect = 0.007
Identities = 45/130 (34%), Positives = 57/130 (43%), Gaps = 9/130 (6%)
Query: 33 KSIGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGS--SSSGSSISSARSSGGGSSG 90
+S GT S C + TS C SSG SS S S SS SS S +SSG S+
Sbjct: 239 QSSGTSSTSCSWQSSRTSSTCSC-----QSSGTSSTSCSCQSSGTSSTCSCQSSGTSSTS 293
Query: 91 SSSGSSIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGS 150
S SS + F + S SS + S+ + SS S+S SSG+ S S
Sbjct: 294 CSCQSSRTSSTCSCQFSRTSSTSCSCQSSRTSSTC--SCQSSGTSSTSCICWSSGTSSTS 351
Query: 151 SSSHSSSSSS 160
S S +SS
Sbjct: 352 CSGRFSGTSS 361
Score = 35.8 bits (81), Expect = 0.099
Identities = 95/382 (24%), Positives = 132/382 (34%), Gaps = 37/382 (9%)
Query: 126 QGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRG 185
+ +S S SS + S S S +SS+ S SS +S ++Q S+ + +S G
Sbjct: 12 RASSSSCSCQSSQTSSTCSCQSSQTSSTCSCQSSGTSSTSCNWQSSRTSSTCSCQSS--G 69
Query: 186 ILNPSQPGQSSSSSQTFGVSSSGQSVSS-------NQRPC---SSDIPDSPCS-GGPIVS 234
+ S QSS +S T SSG S +S C SS + CS S
Sbjct: 70 TSSTSCSCQSSETSSTCSCQSSGTSSTSCSWQFSRTSSTCCCQSSRTSSTSCSCQSSRTS 129
Query: 235 HSGPYIPSSHSVS----GGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVD 290
+ SS + S R S C + G C +S
Sbjct: 130 STSCSCQSSRTSSTCSCQTSRTSSTSCSYQSSRTSSTCS---CQSSGTSSTSCNWQSSRT 186
Query: 291 KSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKY 350
S + G SS SY S + + S G S + +
Sbjct: 187 SSTCSCQSSGTSSTSYSCQSSGTSSTCSCQSSGTSSTSCSCQSSGTSSTCS----CQSSG 242
Query: 351 FSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGL 410
SS S SS + Q GT C S+G+ CS SS S+S S
Sbjct: 243 TSSTSCSWQSSRTSSTCSCQSSGTSSTS-CSCQSSGTSSTCSCQSSGTSSTSCSCQS--- 298
Query: 411 PYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGG 470
S + S CS + + S+S S QSS C S S +S C+ SS T +
Sbjct: 299 ------SRTSSTCSCQFSRTSSTSCSCQSSRTSSTCSCQS-SGTSSTSCICWSSGTSSTS 351
Query: 471 PDG--SPHPDPSAGAKPCGSSS 490
G S S + G+SS
Sbjct: 352 CSGRFSGTSSTSCNCRSSGTSS 373
>gi|169173184 PREDICTED: hypothetical protein [Homo sapiens]
Length = 1230
Score = 58.2 bits (139), Expect = 2e-08
Identities = 113/409 (27%), Positives = 159/409 (38%), Gaps = 41/409 (10%)
Query: 62 SSGFSSYSGS---SSSGSSISSARSSGGGSSGSSSGSSI-------AQGGSAGSFKPGTG 111
+SG S+ SGS SSS S +S S+ G +S S+SG+SI + S S +G
Sbjct: 9 ASGVSTPSGSGWASSSASG-ASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSG 67
Query: 112 YSQVSYSSGSGSSLQG-ASGSSQLGSSSSHSG-SSGSHSGSSSSHSSSSSSFQFSSSSFQ 169
++ S S S S G AS S+ S+ S SG +S S SG+S S +S S +S
Sbjct: 68 WASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDSGWASPSVSGASIP 127
Query: 170 V---GNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSP 226
+ SA + S G +PS S+SS G +S S +S C+S S
Sbjct: 128 SAFWASPSASGASTPSDSGWASPSASWASTSSDS--GWASPSASWTSPSASCAS----SS 181
Query: 227 CSGGPIVSHSGPYIPS----SHSVSGGQRP-----VVVVVDQHGSGAPGVVQGPPCSNGG 277
SG S SG PS S S S P D + + P S
Sbjct: 182 ASGASTPSDSGWASPSVFWVSPSTSWASSPSDFGWASTPSDSGWASSSASCISPSASGAS 241
Query: 278 L---PGKPCPPITSVDKSYGGYEV---VGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVK 331
G P + V S G +S S +T G + P + +
Sbjct: 242 TSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWASSSASW 301
Query: 332 GSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPC 391
S S ++ P +S S + + +AS A A G G +T G
Sbjct: 302 ASAPSDSGSSSPSVSRASTLSVSGW--ASFSASGASAPSDSGWTSHSASGVSTTSDSGWA 359
Query: 392 SPSSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSS 440
SPS+S +SS +S P S S S S P ++S S+S +S
Sbjct: 360 SPSASGASTSSDSGWAS--PSASWASPSASGASTPSDSGWASPSASGAS 406
Score = 55.5 bits (132), Expect = 1e-07
Identities = 63/214 (29%), Positives = 98/214 (45%), Gaps = 19/214 (8%)
Query: 49 TSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKP 108
+SP+D SG++S S S S S+ ++ SS G + S S S ++ S S
Sbjct: 209 SSPSDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWA-SPSASWVSTSTSRASTSS 267
Query: 109 GTGYSQVSYSSGSGSSLQGASG----SSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFS 164
+G++ SS S S+ SG S+ SSS+ S+ S SGSSS S +S+ S
Sbjct: 268 DSGWAS---SSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVS 324
Query: 165 SSSFQVGNGSALPTN----DNSYRGILNPSQPGQSSSSSQTFGVSSSGQS-----VSSNQ 215
+ +G++ P++ +S G+ S G +S S+ G S+S S +S
Sbjct: 325 GWASFSASGASAPSDSGWTSHSASGVSTTSDSGWASPSAS--GASTSSDSGWASPSASWA 382
Query: 216 RPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGG 249
P +S SG S SG +PS+ S+ G
Sbjct: 383 SPSASGASTPSDSGWASPSASGASMPSAPSLCPG 416
Score = 54.7 bits (130), Expect = 2e-07
Identities = 113/412 (27%), Positives = 148/412 (35%), Gaps = 56/412 (13%)
Query: 102 SAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSS--SSHSGSSGSHSGSSSSHSSSSS 159
S S G+G++ S S S S G + S G+S S +S S SG+S+ +S +
Sbjct: 10 SGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNSGWA 69
Query: 160 SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCS 219
SF S +S +G A P S PS G +S S+SG S+ S+
Sbjct: 70 SFSASWASIPSDSGWASP----SASWASTPSDSGWASP-------SASGASIPSD----- 113
Query: 220 SDIPDSPCSGGPIVSHSGPYIPS----SHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSN 275
SG S SG IPS S S SG P G +P S+
Sbjct: 114 --------SGWASPSVSGASIPSAFWASPSASGASTP-----SDSGWASPSASWASTSSD 160
Query: 276 GGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYP-VGYFTKENPVKGSP 334
G P TS S G S+ S G P V + + SP
Sbjct: 161 SGW-ASPSASWTSPSASCASSSASGASTPS--------DSGWASPSVFWVSPSTSWASSP 211
Query: 335 GVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPS 394
+A+ P S S++ I PS S AS++ + S S S
Sbjct: 212 SDFGWASTPSDSGWASSSASCISPSASGASTSSDSGWASPSASWVSTSTSRASTSSDSGW 271
Query: 395 SSRVPSSSSISSSSG--LPYHPCGSASQSPCSPPGTGSFSSSSSSQS-----SGKIILQP 447
+S S SI+S SG P S+S S S P SS S S++ SG
Sbjct: 272 ASSSASWDSITSDSGWVCPSASWASSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSA 331
Query: 448 CG-SKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGAKPCGSSSAGKIPCRS 498
G S S SG S S ++ T S PSA S S P S
Sbjct: 332 SGASAPSDSGWTSHSASGVSTT---SDSGWASPSASGASTSSDSGWASPSAS 380
Score = 51.6 bits (122), Expect = 2e-06
Identities = 112/426 (26%), Positives = 161/426 (37%), Gaps = 33/426 (7%)
Query: 77 SISSARSSGGGSSGSSSGSSIAQGGS-AGSFKPGTGYSQVSYSSGSGS-SLQGASGSSQL 134
S +S S+ GS +SS +S A S +G P + + SG S S GAS S
Sbjct: 7 SRASGVSTPSGSGWASSSASGASTPSNSGWASPSASGASIPSDSGWASPSASGASTPSNS 66
Query: 135 G--SSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQP 192
G S S+ S S SG +S +S +S+ S + +G+++P++ G +PS
Sbjct: 67 GWASFSASWASIPSDSGWASPSASWASTPSDSGWASPSASGASIPSDS----GWASPSVS 122
Query: 193 GQSSSSSQTFGVSSSGQSVSSNQ---RPCSSDIPDSPCSG--GPIVSHSGPYIP-SSHSV 246
G S S+ S+SG S S+ P +S S SG P S + P +S S
Sbjct: 123 GASIPSAFWASPSASGASTPSDSGWASPSASWASTSSDSGWASPSASWTSPSASCASSSA 182
Query: 247 SGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSY 306
SG P G +P V P ++ P + S G+ S S
Sbjct: 183 SGASTP-----SDSGWASPSVFWVSPSTSWA--SSPSDFGWASTPSDSGWASSSASCISP 235
Query: 307 LVPGMTYS--KGKIYPVGYFTKENPVKGSPGVPSFAAGPPISEGKYFS-SNPIIPSQSAA 363
G + S G P + + + S S A S S S + PS S A
Sbjct: 236 SASGASTSSDSGWASPSASWVSTSTSRASTSSDSGWASSSASWDSITSDSGWVCPSASWA 295
Query: 364 SSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSSSRVPSSSSISSSSGLPYHPCGSASQSPC 423
SS+ ++ + S S S +S S +S S SG H S +
Sbjct: 296 SSSASWASAPSDSGSSSPSVSRASTLSVSGWASFSASGASAPSDSGWTSHSASGVSTTSD 355
Query: 424 SPPGTGSFSSSSSSQSSGKIILQPCGSKSSSSGHPCMSVSSLTLTGGPDGSPHPDPSAGA 483
S + S S +S+S SG S S+S P S +S T G P S +
Sbjct: 356 SGWASPSASGASTSSDSG------WASPSASWASPSASGAS---TPSDSGWASPSASGAS 406
Query: 484 KPCGSS 489
P S
Sbjct: 407 MPSAPS 412
Score = 41.6 bits (96), Expect = 0.002
Identities = 39/116 (33%), Positives = 56/116 (48%), Gaps = 6/116 (5%)
Query: 67 SYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS-----SGS 121
S SGSSS S +S S G +S S+SG+S A S + +G S S S S S
Sbjct: 306 SDSGSSSPSVSRASTLSVSGWASFSASGAS-APSDSGWTSHSASGVSTTSDSGWASPSAS 364
Query: 122 GSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
G+S SG + +S + +SG+ + S S +S S+S S+ + GS P
Sbjct: 365 GASTSSDSGWASPSASWASPSASGASTPSDSGWASPSASGASMPSAPSLCPGSCFP 420
>gi|60097902 filaggrin [Homo sapiens]
Length = 4061
Score = 57.4 bits (137), Expect = 3e-08
Identities = 51/164 (31%), Positives = 70/164 (42%), Gaps = 10/164 (6%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
T +G S +SGS S+ + SG GS S S + A S +G+SQV
Sbjct: 2496 TSQGRSDASHGHSGSRSASRQTRNDEQSGDGSRHSGS-----RHHEASSRADSSGHSQV- 2549
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176
G G S +G S GSS S S HS S S S+S S+ Q+ +GS
Sbjct: 2550 ---GQGQS-EGPRTSRNWGSSFSQDSDSQGHSEDSERWSGSASRNHHGSAQEQLRDGSRH 2605
Query: 177 PTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
P + R S S ++ SS GQ+ SS+++ SS
Sbjct: 2606 PRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2649
Score = 53.9 bits (128), Expect = 4e-07
Identities = 51/164 (31%), Positives = 65/164 (39%), Gaps = 10/164 (6%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
T +G S SGS S+ + SG GS S S + A S+ + +SQV
Sbjct: 1199 TSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGS-----RHHEAASWADSSRHSQVG 1253
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176
SGS S GSS S S HS S S S+S SS Q +GS
Sbjct: 1254 QEQSSGSRT-----SRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRDGSRH 1308
Query: 177 PTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
P R S S + SS GQ+VSS+++ SS
Sbjct: 1309 PGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSS 1352
Score = 53.1 bits (126), Expect = 6e-07
Identities = 46/167 (27%), Positives = 67/167 (40%), Gaps = 7/167 (4%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
D SG S Y S ++ S A G +S + + GS G+ + + S +G
Sbjct: 1510 DRSGHSGYHHSHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAG 1569
Query: 121 SGSSLQ-------GASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
S Q G+ S + GSS S S HS S S S+S + S+ Q +G
Sbjct: 1570 SSRHSQVGQGESAGSKTSRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRHG 1629
Query: 174 SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
S P + R S S ++ SS GQ+ SS ++ SS
Sbjct: 1630 SRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSS 1676
Score = 52.0 bits (123), Expect = 1e-06
Identities = 50/169 (29%), Positives = 74/169 (43%), Gaps = 11/169 (6%)
Query: 61 DSSGFSS--YSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS-- 116
DSSG S +S ++S G S +S R G S S + + Q G GS G+ + + S
Sbjct: 2807 DSSGHSGSHHSHTTSQGRSDAS-RGQSGSRSASRTTRNEEQSGD-GSRHSGSRHHEASTH 2864
Query: 117 -----YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG 171
+S +G+ S + GSS S S HS S S S+S S+ Q+
Sbjct: 2865 ADISRHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHHGSAQEQLR 2924
Query: 172 NGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
+GS P + R S S ++ SS GQ+ SS+++ SS
Sbjct: 2925 DGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSS 2973
Score = 51.2 bits (121), Expect = 2e-06
Identities = 50/164 (30%), Positives = 68/164 (41%), Gaps = 10/164 (6%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
T +G S SGS S+ + SG G+ S S + A S + +SQV
Sbjct: 550 TSQGRSDASHGQSGSRSASRQTRNEEQSGDGTRHSGS-----RHHEASSQADSSRHSQV- 603
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSAL 176
G G S G S GSS S S HS S S S+S S+ Q +GS
Sbjct: 604 ---GQGQS-SGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQEQSRDGSRH 659
Query: 177 PTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
P + + R S S ++ SSSGQ+ SS+++ SS
Sbjct: 660 PRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSS 703
Score = 48.9 bits (115), Expect = 1e-05
Identities = 52/167 (31%), Positives = 71/167 (42%), Gaps = 7/167 (4%)
Query: 61 DSSGFSS--YSGSSSSGSSISSARSSGGGSSGSSSGSSIAQG-GSAGSFKPGTGYSQVSY 117
D SG S +S ++S G S +S SG S+ + + G GS S+ S +
Sbjct: 3455 DRSGHSGSHHSHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQAD 3514
Query: 118 SSGSGSSLQGASG----SSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNG 173
SS S QG S S GSS S S HS S S S+S S+ Q +G
Sbjct: 3515 SSRHSQSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGSAQEQSRDG 3574
Query: 174 SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
S PT+ + R S S + SS GQ+ SS+++ SS
Sbjct: 3575 SRHPTSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 3621
Score = 48.5 bits (114), Expect = 1e-05
Identities = 44/165 (26%), Positives = 65/165 (39%), Gaps = 10/165 (6%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSA---GSFKPGTGYSQVSYSSGSG 122
S +SGS S ++ + G SGS S S + GS G+ + + S +
Sbjct: 864 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADIS 923
Query: 123 SSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVG-------NGSA 175
Q G S+ +S GSS S S HS S + S+S G +GS
Sbjct: 924 RHSQAGQGQSEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSR 983
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
P + + R S S + SS GQ+ SS+++ SS
Sbjct: 984 HPRSHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSS 1028
Score = 48.5 bits (114), Expect = 1e-05
Identities = 47/165 (28%), Positives = 64/165 (38%), Gaps = 10/165 (6%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIA----QGGSAGSFKPGTGYSQVSYSSGS 121
S +SGS S ++ + G SGS S S Q G + S++ S
Sbjct: 2161 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSS 2220
Query: 122 GSSLQGASGSS------QLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
SL G SS GSS S S HS S S S+S S+ Q +GS
Sbjct: 2221 RHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSR 2280
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
P + + R S S + SS GQ+ SS+++ SS
Sbjct: 2281 HPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSS 2325
Score = 48.5 bits (114), Expect = 1e-05
Identities = 51/172 (29%), Positives = 72/172 (41%), Gaps = 17/172 (9%)
Query: 61 DSSGFSS--YSGSSSSGSSISSARSSGGGS----------SGSSSGSSIAQGGSAGSFKP 108
DSSG S +S ++S G S +S SG S SG SS S+++ A +
Sbjct: 3131 DSSGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHAD 3190
Query: 109 GTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF 168
+ +SQ GS S + GSS S S HS S S S+S S
Sbjct: 3191 ISRHSQAVQGQSEGSRR-----SRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQE 3245
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
Q +GS P + + R S S ++ SS GQ+ SS+++ SS
Sbjct: 3246 QSRHGSRHPRSHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSS 3297
Score = 48.1 bits (113), Expect = 2e-05
Identities = 47/168 (27%), Positives = 73/168 (43%), Gaps = 9/168 (5%)
Query: 61 DSSGFS-SYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSS 119
DSSG S S+ ++S +R G S S + Q G GS G+ + + S +
Sbjct: 1834 DSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSRQTRNEKQSGD-GSRHSGSRHHEASSRA 1892
Query: 120 GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTN 179
S Q G S +S + GSS S S HS S + S+S +G+ +
Sbjct: 1893 DSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRD 1952
Query: 180 DNSYRGILNPSQP--GQSSSSSQTFGV-----SSSGQSVSSNQRPCSS 220
+ + G + + G S+ SS+ G SS GQ+ SS+++ SS
Sbjct: 1953 GSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSS 2000
Score = 47.4 bits (111), Expect = 3e-05
Identities = 54/178 (30%), Positives = 72/178 (40%), Gaps = 16/178 (8%)
Query: 59 KGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
+G S S SGSS S S G +G+S+G G + S+ S S
Sbjct: 455 RGRSGERSGRSGSSLYQVSTHEQPDSAHGRTGTSTG-----GRQGSHHEQARDSSRHSAS 509
Query: 119 SGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF-QVGNGSALP 177
+++G GSS+ G SH S + SG S SH S ++S S +S Q G+ SA
Sbjct: 510 QEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGHSGSHHSHTTSQGRSDASHGQSGSRSASR 569
Query: 178 TNDNS--------YRGILNPSQPGQSSSS--SQTFGVSSSGQSVSSNQRPCSSDIPDS 225
N + G + Q+ SS SQ SSG S NQ S DS
Sbjct: 570 QTRNEEQSGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDS 627
Score = 47.4 bits (111), Expect = 3e-05
Identities = 71/252 (28%), Positives = 93/252 (36%), Gaps = 53/252 (21%)
Query: 58 GKGDSSGFSSYSGSSSSG----SSISSARSSGGGSSGSSSG-----SSIAQGGSA-GSFK 107
G + S S SG +G S SAR GG SG S S+ Q SA G +
Sbjct: 3345 GHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTR 3404
Query: 108 PGTGYSQVSY------------SSGSGSSLQGASGSSQLGSSSSH-------SGSSGSH- 147
TG Q S+ S +++G GSS+ G SH SG SGSH
Sbjct: 3405 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRGHPGSSRRGRQGSHYEQSVDRSGHSGSHH 3464
Query: 148 --------SGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSS 199
S +S S S S+ + + + Q G+GS +S+ S SS S
Sbjct: 3465 SHTTSQGRSDASRGQSGSRSASRQTRNDEQSGDGSR-----HSWSHHHEASTQADSSRHS 3519
Query: 200 QTFGVSSSGQSVSSNQRPCSSDIPDSP--------CSGGPIVSHSGPYIPSSHSVSGGQR 251
Q+ S+G S NQ S DS SG +H G S G +
Sbjct: 3520 QSGQGQSAGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHRGS--AQEQSRDGSRH 3577
Query: 252 PVVVVVDQHGSG 263
P D+ G G
Sbjct: 3578 PTSHHEDRAGHG 3589
Score = 46.6 bits (109), Expect = 6e-05
Identities = 67/239 (28%), Positives = 90/239 (37%), Gaps = 36/239 (15%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSS---GSSIAQ-------GGSAGSFK 107
G + S S SG +G S + S SG S GS + Q S G
Sbjct: 752 GHSEDSDTQSVSGHGQAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTG 811
Query: 108 PGTGYSQVSY------------SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG-SSSSH 154
P TG Q S+ S +++G GSS+ G SH S SG S S H
Sbjct: 812 PSTGVRQGSHHEQARDNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQSVDRSGHSGSHH 871
Query: 155 SSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPG----QSSSSSQTFGVSSSGQS 210
S ++S + +S Q G+ SA T N + G ++SS + S +GQ
Sbjct: 872 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQG 931
Query: 211 VS----SNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAP 265
S +++R SS DS G HS S S S R +HGS P
Sbjct: 932 QSEGSRTSRRQGSSVSQDSDSEG-----HSEDSERWSGSASRNHRGSAQEQSRHGSRHP 985
Score = 46.6 bits (109), Expect = 6e-05
Identities = 44/158 (27%), Positives = 62/158 (39%), Gaps = 10/158 (6%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYS---QVSYSSGSG 122
S + + G S +R SG + +SSG A PG + Q S S
Sbjct: 3256 SHHEDRAGHGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 3315
Query: 123 SSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNS 182
S + SS + S H GSSGS + S HS S + S G+G A P +
Sbjct: 3316 SGIPRGQASSAV-RDSRHWGSSGSQASDSEGHSEESDTQSVS------GHGQAGPHQQSH 3368
Query: 183 YRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
+ S S S + VS+ QS S++ R +S
Sbjct: 3369 QESARDRSGGRSGRSGSFLYQVSTHEQSESAHGRTRTS 3406
Score = 46.2 bits (108), Expect = 7e-05
Identities = 104/457 (22%), Positives = 157/457 (34%), Gaps = 52/457 (11%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGS-------------SGSSSGSSIAQGGSA 103
T +G S SGS S+ + SG GS + SS S QG SA
Sbjct: 3468 TSQGRSDASRGQSGSRSASRQTRNDEQSGDGSRHSWSHHHEASTQADSSRHSQSGQGQSA 3527
Query: 104 GSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQF 163
G P T +Q S S S QG S S+ S S+ S +H GS+ S S
Sbjct: 3528 G---PRTSRNQGS-SVSQDSDSQGHSEDSERWSGSA----SRNHRGSAQEQSRDGSRHPT 3579
Query: 164 SSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIP 223
S + G+G + ++ S S GQ++SS + SS+G+ S+ + +
Sbjct: 3580 SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQ-ARSSAGERHGSHHQQSADSSR 3638
Query: 224 DSPCSGGPIVS------HSGPY-IPSSHSVSGGQRPVVVVVDQHGSGAP------GVVQG 270
S G S H G +S S + V HG P +G
Sbjct: 3639 HSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRG 3698
Query: 271 PPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPV 330
G G +++ ++S + G S+ ++ ++ +
Sbjct: 3699 RSAGRSGRSGSFLYQVSTHEQSESAHGRAGPSTGGRQGSRHEQARDSSRHSASQEGQDTI 3758
Query: 331 KGSPGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGP 390
+G PG S G +G Y + + S + G G +GS+
Sbjct: 3759 RGHPG--SRRGG---RQGSYHEQS----VDRSGHSGSHHSHTTSQGRSDASHGQSGSRS- 3808
Query: 391 CSPSSSRVPSSSSISSSSGLPYHPCGS-ASQSPCSPPGTGSFSSSSSSQSSGKIILQPCG 449
S + S S SG +H + A S S G G + S S+ G + Q
Sbjct: 3809 ASRETRNEEQSGDGSRHSGSRHHEASTQADSSRHSQSGQGESAGSRRSRRQGSSVSQDSD 3868
Query: 450 SKSSSSGHPCMSVSSLTLTGGP------DGSPHPDPS 480
S++ S S+ G DGS HP S
Sbjct: 3869 SEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGSS 3905
Score = 45.8 bits (107), Expect = 1e-04
Identities = 69/238 (28%), Positives = 90/238 (37%), Gaps = 48/238 (20%)
Query: 35 IGTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSG-----SSSSGSSISS---ARSSGG 86
+G+ + +D +R + G G S+ S SG SSS G + SS ARSS G
Sbjct: 1943 LGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAG 2002
Query: 87 GSSGS-----SSGSSIAQG---GSAGSFKPGTGYSQVSYSSGSGS------------SLQ 126
GS S+ SS G G A S +G+ S S S S S Q
Sbjct: 2003 ERHGSHHQLQSADSSRHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQ 2062
Query: 127 GASGSSQLGSSSSHSGSSGSHSGSS-------SSHSSSSSSFQFSSSSFQVGNG------ 173
G +G Q S G SG SG S S+H S S+ S+ S G
Sbjct: 2063 GKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQA 2122
Query: 174 ------SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDS 225
SA ++ RG PS+ G+ S Q V SG S S + S D+
Sbjct: 2123 QDSSRHSASQEGQDTIRGHPGPSRGGR-QGSHQEQSVDRSGHSGSHHSHTTSQGRSDA 2179
Score = 45.4 bits (106), Expect = 1e-04
Identities = 44/158 (27%), Positives = 62/158 (39%), Gaps = 10/158 (6%)
Query: 66 SSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYS---QVSYSSGSG 122
S + + G S S+R SG + +SSG A PG + Q S S
Sbjct: 987 SHHEDRAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRH 1046
Query: 123 SSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNS 182
S + SS + S H GSSGS + S HS S + S G+G P +
Sbjct: 1047 SGIPRRQASSAV-RDSGHWGSSGSQASDSEGHSEESDTQSVS------GHGQDGPHQQSH 1099
Query: 183 YRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
+ S S S + VS+ QS S++ R +S
Sbjct: 1100 QESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTRTS 1137
Score = 45.4 bits (106), Expect = 1e-04
Identities = 65/239 (27%), Positives = 90/239 (37%), Gaps = 36/239 (15%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG----------------SSIAQGG 101
G + S S S +GS S + S G SG +SG SS G
Sbjct: 3021 GHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 3080
Query: 102 SAGSFKPGTGYSQVSYSSGSGSS------LQGASGSSQLGSSSSHSGSSGSHSGSSSS-H 154
+ + G+ + Q SS +S ++G GSS+ G H S SG S S H
Sbjct: 3081 PSTRGRQGSRHEQAQDSSRHSASQYGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 3140
Query: 155 SSSSSSFQFSSSSFQVGNGSALPTNDN------SYRGILNPSQPGQSSSSSQTFGVSSSG 208
S ++S + +S Q G+ SA T N S R ++ + + + G
Sbjct: 3141 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQG 3200
Query: 209 QSVSS--NQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAP 265
QS S ++R SS DS G HS S S S R V +HGS P
Sbjct: 3201 QSEGSRRSRRQGSSVSQDSDSEG-----HSEDSERWSGSASRNHRGSVQEQSRHGSRHP 3254
Score = 45.1 bits (105), Expect = 2e-04
Identities = 105/424 (24%), Positives = 146/424 (34%), Gaps = 34/424 (8%)
Query: 36 GTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGS 95
G+ + +D +R + + G G S+ S SG+ + +S SGG ++ S +
Sbjct: 3565 GSAQEQSRDGSRHPTSHHEDRAGHGHSAESSRQSGTHHAENS------SGGQAASSHEQA 3618
Query: 96 SIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS 155
+ G GS + Q S S S + SS + S H GSSGS + S HS
Sbjct: 3619 RSSAGERHGS------HHQQSADSSRHSGIGHGQASSAV-RDSGHRGSSGSQASDSEGHS 3671
Query: 156 SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ 215
S + S+ +G A P + S S S + VS+ QS S++
Sbjct: 3672 EDSDTQSVSA------HGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHG 3725
Query: 216 RPCSSDIPDSPCSGGPIVS-HSGPYIPSSHSVS-GGQRPVVVVVDQHGSGAPGVVQGPPC 273
R P +GG S H S HS S GQ + G G
Sbjct: 3726 RA-------GPSTGGRQGSRHEQARDSSRHSASQEGQDTIRGHPGSRRGGRQGSYHEQSV 3778
Query: 274 SNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGS 333
G G TS +S + G S S S G E +
Sbjct: 3779 DRSGHSGSHHSHTTSQGRSDASHGQSGSRSASRETRNEEQSGDGSRHSGSRHHEASTQAD 3838
Query: 334 PGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSP 393
S +G S G S S S S + A+ + GS S
Sbjct: 3839 SSRHS-QSGQGESAGSRRSRRQ-GSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSR 3896
Query: 394 SSSRVPSSSSISSSSGLPYHPCGSASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSS 453
SR P SS ++S + P S S S G S S S+ SG +Q GS S
Sbjct: 3897 DGSRHPGSSHRDTASHVQSSPVQSDS-STAKEHGHFSSLSQDSAYHSG---IQSRGSPHS 3952
Query: 454 SSGH 457
SS +
Sbjct: 3953 SSSY 3956
Score = 44.7 bits (104), Expect = 2e-04
Identities = 104/451 (23%), Positives = 150/451 (33%), Gaps = 46/451 (10%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
T +G S SGS S+ + + S GS S S A + S G Q
Sbjct: 875 TSQGRSDASRGQSGSRSASRTTRNEEQSRDGSRHSGSRHHEASSHADISRHSQAGQGQ-- 932
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHS--------GSSGSHSGSSSSHSSSSSSFQFSSSSF 168
S GS +S + S SQ S HS +S +H GS+ S S S
Sbjct: 933 -SEGSRTSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSAQEQSRHGSRHPRSHHED 991
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCS 228
+ G+G + ++ S S GQ++SS + S + S +Q+ S S S
Sbjct: 992 RAGHGHSADSSRQSGTPHAETSSGGQAASSHEQARSSPGERHGSRHQQSADS----SRHS 1047
Query: 229 GGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITS 288
G P S S H S G + D G Q P + ++
Sbjct: 1048 GIPRRQASSAVRDSGHWGSSGSQ----ASDSEGHSEESDTQSVSGHGQDGPHQQSHQESA 1103
Query: 289 VDKSYGGYEVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGS--------------- 333
D S G G S S++ T+ + + T +GS
Sbjct: 1104 RDWSGGR----SGRSGSFIYQVSTHEQSESAHGRTRTSTGRRQGSHHEQARDSSRHSASQ 1159
Query: 334 PGVPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSP 393
G + A P G S+ + S + G G +GS+ S
Sbjct: 1160 EGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHHSHTTSQGRSDASHGQSGSRS-ASR 1218
Query: 394 SSSRVPSSSSISSSSGLPYHPCGS-ASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKS 452
+ + S S SG +H S A S S G S S +S+ G + Q S+
Sbjct: 1219 QTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSER 1278
Query: 453 SSSGHPCMSVSSLTLTGGP------DGSPHP 477
S +S S+ G DGS HP
Sbjct: 1279 HSDDSERLSGSASRNHHGSSREQSRDGSRHP 1309
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/161 (28%), Positives = 65/161 (40%), Gaps = 9/161 (5%)
Query: 109 GTGYSQVSYSSGSGSS---LQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSS 165
G SQV+ S +S LQ + + GS S S HS S HS S+S S
Sbjct: 265 GKSSSQVNRSRHENTSQVPLQESRTRKRRGSRVSQDRDSEGHSEDSERHSGSASRNHHGS 324
Query: 166 SSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDS 225
+ Q +GS P + + R S S ++ SS GQ+ SS+++ SS P
Sbjct: 325 AWEQSRDGSRHPRSHDEDRASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSS--PGE 382
Query: 226 PCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG 266
G H S HS +G + V D+ G+ G
Sbjct: 383 RHGSG----HQQSADSSRHSATGRGQASSAVSDRGHRGSSG 419
Score = 44.3 bits (103), Expect = 3e-04
Identities = 46/172 (26%), Positives = 65/172 (37%), Gaps = 11/172 (6%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
T +G S SGS S+ SG GS S S A + S G Q
Sbjct: 2172 TSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQGQ-- 2229
Query: 117 YSSGSGSSLQGASGSSQLGSSSSHS--------GSSGSHSGSSSSHSSSSSSFQFSSSSF 168
SSG +S S SQ S HS +S +H GS+ S S S
Sbjct: 2230 -SSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPRSHHED 2288
Query: 169 QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
+ G+G + ++ S S GQ++SS + S+ + S +Q+ S
Sbjct: 2289 RAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADS 2340
Score = 43.9 bits (102), Expect = 4e-04
Identities = 59/203 (29%), Positives = 79/203 (38%), Gaps = 30/203 (14%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG--------------SSIAQGGSA 103
G + S S S +G S + S G SG SSG S G SA
Sbjct: 2049 GHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRSGSFLYQVSTHEQSESTHGQSA 2108
Query: 104 GSF--KPGTGYSQVSYSSGSGSS------LQGASGSSQLGSSSSHSGSSGSHSGSSSS-H 154
S + G+ Y Q SS +S ++G G S+ G SH S SG S S H
Sbjct: 2109 PSTGGRQGSHYDQAQDSSRHSASQEGQDTIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHH 2168
Query: 155 SSSSSSFQFSSSSFQVGNGSA-LPTNDNSYRG---ILNPSQPGQSSSSSQTFGVSSSGQS 210
S ++S + +S Q G+ SA T D G + S ++SS + + S GQ
Sbjct: 2169 SHTTSQGRSDASRGQSGSRSASRKTYDKEQSGDGSRHSGSHHHEASSWADSSRHSLVGQG 2228
Query: 211 VSS---NQRPCSSDIPDSPCSGG 230
SS RP S + S G
Sbjct: 2229 QSSGPRTSRPRGSSVSQDSDSEG 2251
Score = 43.9 bits (102), Expect = 4e-04
Identities = 52/188 (27%), Positives = 74/188 (39%), Gaps = 21/188 (11%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYSSG 120
D +G + SS + + SSGG ++ S + + G GS + Q S S
Sbjct: 2288 DRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGS------HHQQSADSS 2341
Query: 121 SGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTND 180
S + SS + S H GSSGS + S HS S + S+ +G A P
Sbjct: 2342 RHSGIGHGQASSAV-RDSGHRGSSGSQASDSEGHSEDSDTQSVSA------HGQAGPHQQ 2394
Query: 181 NSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYI 240
+ S S S + VS+ QS S++ R +S +GG SH
Sbjct: 2395 SHQESTRGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTS-------TGGRQGSHHKQAR 2447
Query: 241 PSS-HSVS 247
SS HS S
Sbjct: 2448 DSSRHSTS 2455
Score = 43.9 bits (102), Expect = 4e-04
Identities = 47/163 (28%), Positives = 64/163 (39%), Gaps = 10/163 (6%)
Query: 59 KGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
+G S+G S SGS S S G +G+S+G G K S+ S S
Sbjct: 2401 RGRSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTG-----GRQGSHHKQARDSSRHSTS 2455
Query: 119 SGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSF-QVGNGSALP 177
++ G GSS G SH SG S SH S ++S S +S G+ SA
Sbjct: 2456 QEGQDTIHGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASR 2515
Query: 178 TNDNSYRGILNPSQPG----QSSSSSQTFGVSSSGQSVSSNQR 216
N + G ++SS + + G S GQ S R
Sbjct: 2516 QTRNDEQSGDGSRHSGSRHHEASSRADSSGHSQVGQGQSEGPR 2558
Score = 43.1 bits (100), Expect = 6e-04
Identities = 67/237 (28%), Positives = 89/237 (37%), Gaps = 48/237 (20%)
Query: 36 GTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSG-----SSSSGSSISS---ARSSGGG 87
G+ + +D +R + G G S+ S SG +SSSG + SS ARSS G
Sbjct: 647 GSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQAASSHEQARSSAGE 706
Query: 88 SSGS-----------SSGSSIAQGGSA--GSFKPGTGYSQVSYSSG--SGSSLQGASGSS 132
GS SG+ Q SA S G+ SQ + S G S Q SG
Sbjct: 707 RHGSRHQLQSADSSRHSGTGHGQASSAVRDSGHRGSSGSQATDSEGHSEDSDTQSVSGHG 766
Query: 133 QLG--------SSSSHSGSSGSHSGS----SSSHSSSSSSFQFSSSSFQVGNG------- 173
Q G S+ SG SGS S+H S SS ++ S V G
Sbjct: 767 QAGHHQQSHQESARDRSGERSRRSGSFLYQVSTHKQSESSHGWTGPSTGVRQGSHHEQAR 826
Query: 174 -----SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDS 225
SA ++ RG S+ G+ S + V SG S S + S D+
Sbjct: 827 DNSRHSASQDGQDTIRGHPGSSRRGRQGSHHEQ-SVDRSGHSGSHHSHTTSQGRSDA 882
Score = 42.4 bits (98), Expect = 0.001
Identities = 49/177 (27%), Positives = 71/177 (40%), Gaps = 21/177 (11%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGS--SGS-----------SSGSSIAQGGSA 103
T +G S SGS S+ + + SG GS SGS S S QG S
Sbjct: 2820 TSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQGQSE 2879
Query: 104 GSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQF 163
GS + S VS S S +G S S+ S S+ S +H GS+ S
Sbjct: 2880 GSRRSRRQGSSVSQDSDS----EGHSEDSERWSGSA----SRNHHGSAQEQLRDGSRHPR 2931
Query: 164 SSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSS 220
S + G+G + ++ S S GQ++SS + S+ + S +Q+ S
Sbjct: 2932 SHQEDRAGHGHSADSSRQSGTRHTQTSSGGQAASSHEQARSSAGERHGSHHQQSADS 2988
Score = 42.0 bits (97), Expect = 0.001
Identities = 53/178 (29%), Positives = 68/178 (38%), Gaps = 16/178 (8%)
Query: 59 KGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSYS 118
+G S S SGS S S G +G S+G G + S+ S S
Sbjct: 1752 RGQSGERSGRSGSFLYQVSTHEQSESAHGRTGPSTG-----GRQRSRHEQARDSSRHSAS 1806
Query: 119 SGSGSSLQGASGSSQLGSSSSH---SGSSGSHSGSSSSHSSSS-----SSFQFSSSSFQV 170
+++G GSS+ G SH S S HSGS SH++S S Q S S
Sbjct: 1807 QEGQDTIRGHPGSSRGGRQGSHYEQSVDSSGHSGSHHSHTTSQERSDVSRGQSGSRSVSR 1866
Query: 171 GNGSALPTNDNS-YRGILN--PSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDS 225
+ + D S + G + S SS SQ SSG S NQ S DS
Sbjct: 1867 QTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSVSQDSDS 1924
Score = 41.6 bits (96), Expect = 0.002
Identities = 47/174 (27%), Positives = 63/174 (36%), Gaps = 26/174 (14%)
Query: 56 LTGKGDSSG--------FSSYSGSSSSGSSISSARSSGG------GSSGSSSGSSIAQGG 101
L G+G SSG S S S G S S R SG GS+ S
Sbjct: 2224 LVGQGQSSGPRTSRPRGSSVSQDSDSEGHSEDSERRSGSASRNHHGSAQEQSRDGSRHPR 2283
Query: 102 SAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF 161
S + G G+S S + +SG S S+G GS S+ SS
Sbjct: 2284 SHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGERHGSHHQQSADSSRH 2343
Query: 162 QFSSSSFQVGNGSA-LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSN 214
+G+G A D+ +RG G +S S+ S QSVS++
Sbjct: 2344 S------GIGHGQASSAVRDSGHRG-----SSGSQASDSEGHSEDSDTQSVSAH 2386
Score = 41.2 bits (95), Expect = 0.002
Identities = 55/189 (29%), Positives = 79/189 (41%), Gaps = 36/189 (19%)
Query: 72 SSSGSSISSARSSGGGSSGSSS----GSSIAQGGSAGSFKPGTGYSQVSYSS-----GSG 122
+S G S S+R SG + +SS SS Q S+ + G+G+ Q + SS G G
Sbjct: 344 ASHGHSADSSRQSGTRHAETSSRGQTASSHEQARSSPGERHGSGHQQSADSSRHSATGRG 403
Query: 123 SSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA---LPTN 179
+ S GSS S + S HS +S + S S G+G A ++
Sbjct: 404 QASSAVSDRGHRGSSGSQASDSEGHSENSDTQSVS-------------GHGKAGLRQQSH 450
Query: 180 DNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPY 239
S RG + G+ S S SS VS++++P S+ +GG SH
Sbjct: 451 QESTRG-----RSGERSGRS-----GSSLYQVSTHEQPDSAHGRTGTSTGGRQGSHHEQA 500
Query: 240 IPSS-HSVS 247
SS HS S
Sbjct: 501 RDSSRHSAS 509
Score = 41.2 bits (95), Expect = 0.002
Identities = 73/252 (28%), Positives = 90/252 (35%), Gaps = 40/252 (15%)
Query: 58 GKGDSSGFSSYSGSSSSG----SSISSARSSGGGSSGSSSG-----SSIAQGGSA-GSFK 107
G + S S SG G S SAR GG SG S S+ Q SA G +
Sbjct: 1076 GHSEESDTQSVSGHGQDGPHQQSHQESARDWSGGRSGRSGSFIYQVSTHEQSESAHGRTR 1135
Query: 108 PGTGYSQVSY------SSGSGSSLQGAS------GSSQLGSSSSHSGSSGSHSGSSSSHS 155
TG Q S+ SS +S +G GS + G SH S SG S SH
Sbjct: 1136 TSTGRRQGSHHEQARDSSRHSASQEGQDTIRAHPGSRRGGRQGSHHEQSVDRSGHSGSHH 1195
Query: 156 SSSSSFQFSSSSF-QVGNGSA-------LPTNDNSYRGILNPSQP---GQSSSSSQTFGV 204
S ++S S +S Q G+ SA + D S + SS SQ
Sbjct: 1196 SHTTSQGRSDASHGQSGSRSASRQTRKDKQSGDGSRHSGSRHHEAASWADSSRHSQVGQE 1255
Query: 205 SSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGA 264
SSG S +Q S DS SG + H S Q + GS
Sbjct: 1256 QSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQ-------SRDGSRH 1308
Query: 265 PGVVQGPPCSNG 276
PG Q S+G
Sbjct: 1309 PGFHQEDRASHG 1320
Score = 40.8 bits (94), Expect = 0.003
Identities = 65/249 (26%), Positives = 85/249 (34%), Gaps = 34/249 (13%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG---------SSIAQGGSA-GSFK 107
G + S S S +G S + S G SG SSG SS Q S G
Sbjct: 1400 GHSEDSDTQSVSAHGQAGPHQQSHKESARGQSGESSGRSRSFLYQVSSHEQSESTHGQTA 1459
Query: 108 PGTG------------YSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS 155
P TG S+ S S +++G GSS+ G S+ S SG S H
Sbjct: 1460 PSTGGRQGSRHEQARNSSRHSASQDGQDTIRGHPGSSRGGRQGSYHEQSVDRSGHSGYHH 1519
Query: 156 SSSSSFQFSSSSF-QVGNGSAL-------PTNDNSYRGILNPSQPGQSSSSSQTFGVSSS 207
S ++ S +S Q G SA + D S +P + SS+ V
Sbjct: 1520 SHTTPQGRSDASHGQSGPRSASRQTRNEEQSGDGSRHSGSRHHEPSTRAGSSRHSQVGQG 1579
Query: 208 GQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPGV 267
+ S R S + S G HS S S S +HGS P
Sbjct: 1580 ESAGSKTSRRQGSSVSQDRDSEG----HSEDSERRSESASRNHYGSAREQSRHGSRNPRS 1635
Query: 268 VQGPPCSNG 276
Q S+G
Sbjct: 1636 HQEDRASHG 1644
Score = 40.8 bits (94), Expect = 0.003
Identities = 55/203 (27%), Positives = 76/203 (37%), Gaps = 31/203 (15%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSG----------------SSIAQGG 101
G + S S S +GS S + S G SG +SG SS G
Sbjct: 2697 GHSEDSDTQSVSAHGQAGSHQQSHQESARGRSGETSGHSGSFLYQVSTHEQSESSHGWTG 2756
Query: 102 SAGSFKPGTGYSQVSYSSGSGSS------LQGASGSSQLGSSSSHSGSSGSHSGSSSS-H 154
+ + G+ + Q SS +S ++G GSS+ G H S SG S S H
Sbjct: 2757 PSTRGRQGSRHEQAQDSSRHSASQDGQDTIRGHPGSSRGGRQGYHHEHSVDSSGHSGSHH 2816
Query: 155 SSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSS------SG 208
S ++S + +S Q G+ SA T N + G + T S G
Sbjct: 2817 SHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADISRHSQAVQG 2876
Query: 209 QSVSS--NQRPCSSDIPDSPCSG 229
QS S ++R SS DS G
Sbjct: 2877 QSEGSRRSRRQGSSVSQDSDSEG 2899
Score = 40.4 bits (93), Expect = 0.004
Identities = 83/304 (27%), Positives = 113/304 (37%), Gaps = 54/304 (17%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQG---GSA------GSFKP 108
G+G SSG + S + GSS+S S G S S S A GSA GS P
Sbjct: 1901 GQGQSSGPRT---SRNQGSSVSQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHP 1957
Query: 109 GTGYS-QVSYSSGSGSSLQGAS----GSSQLGSSSSHS---GSSGSHSGS--------SS 152
G+ + + + + SS Q + SS+ ++SSH S+G GS SS
Sbjct: 1958 GSHHEDRAGHGHSADSSRQSGTRHTESSSRGQAASSHEQARSSAGERHGSHHQLQSADSS 2017
Query: 153 SHS-------------SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSS 199
HS S + S +S G+ T S +G P Q S+
Sbjct: 2018 RHSGIGHGQASSAVRDSGHRGYSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESAR 2077
Query: 200 QTFGVSSSGQS------VSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSS-HSVS-GGQR 251
G SSG+S VS++++ S+ +P +GG SH SS HS S GQ
Sbjct: 2078 GQSG-ESSGRSGSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEGQD 2136
Query: 252 PVVVVVDQHGSGAPGVVQGPPCSNGGLPGKPCPPITSVDKSYGGYEVVGGSSDSYLVPGM 311
+ G G Q G G TS +S + G S S
Sbjct: 2137 TIRGHPGPSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRS----DASRGQSGSRSASRK 2192
Query: 312 TYSK 315
TY K
Sbjct: 2193 TYDK 2196
Score = 40.0 bits (92), Expect = 0.005
Identities = 55/214 (25%), Positives = 86/214 (40%), Gaps = 28/214 (13%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVS 116
+G G S + +SS S ++ G SSG + + QG S G+S+ S
Sbjct: 577 SGDGTRHSGSRHHEASSQADSSRHSQVGQGQSSGPRTSRN--QGSSVSQDSDSQGHSEDS 634
Query: 117 YSSGSGSSLQGASGSSQLGS-------------SSSHSGSSGSHSGSSSSHSSSSSSFQF 163
SGS+ + GS+Q S + H S+ S S + H+ +SSS Q
Sbjct: 635 -ERWSGSASRNHHGSAQEQSRDGSRHPRSHHEDRAGHGHSADSSRKSGTRHTQNSSSGQA 693
Query: 164 SSSSFQV--------GNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ 215
+SS Q G+ L + D+S + + GQ+SS+ + G S S +++
Sbjct: 694 ASSHEQARSSAGERHGSRHQLQSADSSRH---SGTGHGQASSAVRDSGHRGSSGSQATDS 750
Query: 216 RPCSSDIPDSPCSG-GPIVSHSGPYIPSSHSVSG 248
S D SG G H + S+ SG
Sbjct: 751 EGHSEDSDTQSVSGHGQAGHHQQSHQESARDRSG 784
Score = 40.0 bits (92), Expect = 0.005
Identities = 99/449 (22%), Positives = 148/449 (32%), Gaps = 65/449 (14%)
Query: 69 SGSSSSGSSISSARSSGGGS-------------SGSSSGSSIAQGGSAG---SFKPGTGY 112
SGS S + + SG GS + SS S + QG S+G S G+
Sbjct: 1859 SGSRSVSRQTRNEKQSGDGSRHSGSRHHEASSRADSSRHSQVGQGQSSGPRTSRNQGSSV 1918
Query: 113 SQVSYSSGSGSSLQGASGSSQ---LGSSSSHSGSSGSHSGS------SSSHSSSSSSFQF 163
SQ S S G + SGS+ LGS+ S H GS HS+ SS
Sbjct: 1919 SQDSDSQGHSEDSERWSGSASRNHLGSAWEQSRDGSRHPGSHHEDRAGHGHSADSSRQSG 1978
Query: 164 SSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIP 223
+ + G A +++ + S G+ S + S + SS +
Sbjct: 1979 TRHTESSSRGQAASSHEQA------RSSAGERHGSHHQLQSADSSRHSGIGHGQASSAVR 2032
Query: 224 DSPCSGGPIVSHSGPYIPSS--HSVSGGQRPVVV--VVDQHGSGAPGVVQGPPCSNGGLP 279
DS G +SG S HS + V H +G + G
Sbjct: 2033 DSGHRG-----YSGSQASDSEGHSEDSDTQSVSAQGKAGPHQQSHKESARGQSGESSGRS 2087
Query: 280 GKPCPPITSVDKSYGGY----EVVGGSSDSYLVPGMTYSKGKIYPVGYFTKENPVKGSPG 335
G +++ ++S + GG S+ S+ G ++ ++G PG
Sbjct: 2088 GSFLYQVSTHEQSESTHGQSAPSTGGRQGSHYDQAQDSSRHSASQEG----QDTIRGHPG 2143
Query: 336 VPSFAAGPPISEGKYFSSNPIIPSQSAASSAIAFQPVGTGGVQLCGGGSTGSKGPCSPSS 395
P G+ S +S S + G G +GS+ +
Sbjct: 2144 --------PSRGGRQGSHQEQSVDRSGHSGSHHSHTTSQGRSD-ASRGQSGSRSASRKTY 2194
Query: 396 SRVPSSSSISSSSGLPYHPCGS-ASQSPCSPPGTGSFSSSSSSQSSGKIILQPCGSKSSS 454
+ S S SG +H S A S S G G S +S+ G + Q S+ S
Sbjct: 2195 DKEQSGDG-SRHSGSHHHEASSWADSSRHSLVGQGQSSGPRTSRPRGSSVSQDSDSEGHS 2253
Query: 455 ------SGHPCMSVSSLTLTGGPDGSPHP 477
SG + DGS HP
Sbjct: 2254 EDSERRSGSASRNHHGSAQEQSRDGSRHP 2282
Score = 40.0 bits (92), Expect = 0.005
Identities = 44/156 (28%), Positives = 64/156 (41%), Gaps = 24/156 (15%)
Query: 36 GTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGS----SSSGSSISSARSSGGGSSGS 91
G+ + +D +R + G G S+ S SG+ +SSG +S+ S+G
Sbjct: 2269 GSAQEQSRDGSRHPRSHHEDRAGHGHSAESSRQSGTHHAENSSGGQAASSHEQARSSAGE 2328
Query: 92 SSGSSIAQGGSAGSFKPGTGYSQVSY---------SSGS-GSSLQGASGSSQLGSSSSHS 141
GS Q + S G G+ Q S SSGS S +G S S S S+H
Sbjct: 2329 RHGSHHQQSADS-SRHSGIGHGQASSAVRDSGHRGSSGSQASDSEGHSEDSDTQSVSAH- 2386
Query: 142 GSSGSHS--------GSSSSHSSSSSSFQFSSSSFQ 169
G +G H G S+ S S SF + S+ +
Sbjct: 2387 GQAGPHQQSHQESTRGRSAGRSGRSGSFLYQVSTHE 2422
Score = 40.0 bits (92), Expect = 0.005
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 23/181 (12%)
Query: 36 GTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGS 95
G+ + +D +R + G G S+ S SG+ + +S SGG ++ S +
Sbjct: 2593 GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHEQA 2646
Query: 96 SIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS 155
+ G GS + Q S S S + SS + S H G SGS + + HS
Sbjct: 2647 RSSAGERHGS------HHQQSADSSRHSGIGHGQASSAV-RDSGHRGYSGSQASDNEGHS 2699
Query: 156 SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF--GVSSSGQSVSS 213
S + S S GS ++ S RG + G++S S +F VS+ QS SS
Sbjct: 2700 EDSDT---QSVSAHGQAGSHQQSHQESARG-----RSGETSGHSGSFLYQVSTHEQSESS 2751
Query: 214 N 214
+
Sbjct: 2752 H 2752
Score = 40.0 bits (92), Expect = 0.005
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 23/181 (12%)
Query: 36 GTFSDPCKDPTRITSPNDPCLTGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGS 95
G+ + +D +R + G G S+ S SG+ + +S SGG ++ S +
Sbjct: 2917 GSAQEQLRDGSRHPRSHQEDRAGHGHSADSSRQSGTRHTQTS------SGGQAASSHEQA 2970
Query: 96 SIAQGGSAGSFKPGTGYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHS 155
+ G GS + Q S S S + SS + S H G SGS + + HS
Sbjct: 2971 RSSAGERHGS------HHQQSADSSRHSGIGHGQASSAV-RDSGHRGYSGSQASDNEGHS 3023
Query: 156 SSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTF--GVSSSGQSVSS 213
S + S S GS ++ S RG + G++S S +F VS+ QS SS
Sbjct: 3024 EDSDT---QSVSAHGQAGSHQQSHQESARG-----RSGETSGHSGSFLYQVSTHEQSESS 3075
Query: 214 N 214
+
Sbjct: 3076 H 3076
Score = 39.7 bits (91), Expect = 0.007
Identities = 57/197 (28%), Positives = 75/197 (38%), Gaps = 18/197 (9%)
Query: 61 DSSGFSSYSGSSSSGSSISSARSSGGGSSGSS---SGSSIAQGGSAGSFKPGTGYSQVSY 117
DSS S SSGS S + S S S S GSA G+ Q
Sbjct: 1245 DSSRHSQVGQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQ--- 1301
Query: 118 SSGSGSSLQGASGSSQL--GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSA 175
S GS G + G S+ S SG+H SSSH + SS + + SS +GS
Sbjct: 1302 -SRDGSRHPGFHQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSR 1360
Query: 176 LPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSD--IPDSPCSGGPIV 233
+ +S R S G +SS V SG SS + +S+ DS
Sbjct: 1361 HQQSADSSR----HSGIGHRQASS---AVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAH 1413
Query: 234 SHSGPYIPSSHSVSGGQ 250
+GP+ S + GQ
Sbjct: 1414 GQAGPHQQSHKESARGQ 1430
Score = 39.3 bits (90), Expect = 0.009
Identities = 40/136 (29%), Positives = 56/136 (41%), Gaps = 10/136 (7%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSA------GSFKPGT 110
+G+G+S+G SS S S + + S S +S GS+ GS PG+
Sbjct: 3845 SGQGESAGSRRSRRQGSSVSQDSDSEAYPEDSERRSESASRNHHGSSREQSRDGSRHPGS 3904
Query: 111 GYSQVSYSSGSGSSLQGASGSSQLGSSSSHSGSSGSHSG---SSSSHSSSSSSFQFSSSS 167
+ + S +S + + G SS S S HSG S HSSSS +Q +
Sbjct: 3905 SHRDTASHVQSSPVQSDSSTAKEHGHFSSLSQDSAYHSGIQSRGSPHSSSSYHYQSEGTE 3964
Query: 168 FQVGNGSALPTNDNSY 183
Q G S L SY
Sbjct: 3965 RQKGQ-SGLVWRHGSY 3979
Score = 38.9 bits (89), Expect = 0.012
Identities = 50/195 (25%), Positives = 78/195 (40%), Gaps = 19/195 (9%)
Query: 58 GKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGTGYSQVSY 117
G+G+S+G + S GSS+S R S G S S S A GS + + +
Sbjct: 1577 GQGESAGSKT---SRRQGSSVSQDRDSEGHSEDSERRSESASRNHYGSAREQSRH----- 1628
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
GS + + G S+ S SG+ +SS ++SS + + SS +GS
Sbjct: 1629 --GSRNPRSHQEDRASHGHSAESSRQSGTRHAETSSGGQAASSQEQARSSPGERHGSRHQ 1686
Query: 178 TNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSH-- 235
+ +S S G+ SS V SG SS + S+ + +H
Sbjct: 1687 QSADS----STDSGTGRRQDSSV---VGDSGNRGSSGSQASDSEGHSEESDTQSVSAHGQ 1739
Query: 236 SGPYIPSSHSVSGGQ 250
+GP+ S + GQ
Sbjct: 1740 AGPHQQSHQESTRGQ 1754
Score = 38.1 bits (87), Expect = 0.020
Identities = 63/240 (26%), Positives = 90/240 (37%), Gaps = 50/240 (20%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGSSGS-------------SSGSSIAQGGSA 103
T +G S SGS S+ + + SG S S S S QG S
Sbjct: 3144 TSQGRSDASRGQSGSRSASRTTRNEEQSGDSSRHSVSRHHEASTHADISRHSQAVQGQSE 3203
Query: 104 GSFKP---GTGYSQVSYSSG--------SGSSLQGASGSSQL------------------ 134
GS + G+ SQ S S G SGS+ + GS Q
Sbjct: 3204 GSRRSRRQGSSVSQDSDSEGHSEDSERWSGSASRNHRGSVQEQSRHGSRHPRSHHEDRAG 3263
Query: 135 -GSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPG 193
G S+ S SG+ +SS ++SS + + SS +GS + +S R P G
Sbjct: 3264 HGHSADRSRQSGTRHAETSSGGQAASSHEQARSSPGERHGSRHQQSADSSRHSGIPR--G 3321
Query: 194 QSSSS---SQTFGVSSSGQSVSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQ 250
Q+SS+ S+ +G SSG S ++ S G H + S+ SGG+
Sbjct: 3322 QASSAVRDSRHWG--SSGSQASDSEGHSEESDTQSVSGHGQAGPHQQSHQESARDRSGGR 3379
Score = 36.6 bits (83), Expect = 0.058
Identities = 50/195 (25%), Positives = 67/195 (34%), Gaps = 28/195 (14%)
Query: 57 TGKGDSSGFSSYSGSSSSGS--------SISSARSSGGGSSGSSS--GSSIAQGGSAGSF 106
T G + S SS G S S+ SG G SS G S +G S
Sbjct: 1660 TSSGGQAASSQEQARSSPGERHGSRHQQSADSSTDSGTGRRQDSSVVGDSGNRGSSGSQA 1719
Query: 107 KPGTGYSQVSYSS-----GSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSF 161
G+S+ S + G Q + S G S SG SGS S+H S S+
Sbjct: 1720 SDSEGHSEESDTQSVSAHGQAGPHQQSHQESTRGQSGERSGRSGSFLYQVSTHEQSESAH 1779
Query: 162 QFSSSSF------------QVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQ 209
+ S SA ++ RG S+ G+ S + V SSG
Sbjct: 1780 GRTGPSTGGRQRSRHEQARDSSRHSASQEGQDTIRGHPGSSRGGRQGSHYEQ-SVDSSGH 1838
Query: 210 SVSSNQRPCSSDIPD 224
S S + S + D
Sbjct: 1839 SGSHHSHTTSQERSD 1853
Score = 36.6 bits (83), Expect = 0.058
Identities = 49/169 (28%), Positives = 63/169 (37%), Gaps = 28/169 (16%)
Query: 66 SSYSGSSSSGSSISSARS--------SGGGSSG--------SSSGSSIAQGGSAGSF--K 107
S + GSS S +S S S S G +G S+ G S + G +GSF +
Sbjct: 2358 SGHRGSSGSQASDSEGHSEDSDTQSVSAHGQAGPHQQSHQESTRGRSAGRSGRSGSFLYQ 2417
Query: 108 PGTGYSQVSYSSGSGSSLQGASGS--SQLGSSSSHSGSSGS------HSGSSSSHSSSSS 159
T S +G+S G GS Q SS HS S H GSSS S
Sbjct: 2418 VSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTIHGHPGSSSGGRQGSH 2477
Query: 160 SFQFSSSSFQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSG 208
Q S G+ + T+ R + G S+S QT SG
Sbjct: 2478 YEQLVDRSGHSGSHHSHTTSQG--RSDASHGHSGSRSASRQTRNDEQSG 2524
Score = 35.0 bits (79), Expect = 0.17
Identities = 52/170 (30%), Positives = 70/170 (41%), Gaps = 20/170 (11%)
Query: 64 GFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQG--GSAGSFKPGTGYSQ-VSYSSG 120
G + S GS AR S S+ S G +G GS+ + G+ + Q V+ S
Sbjct: 483 GRTGTSTGGRQGSHHEQARDSSRHSA-SQEGQDTIRGHPGSSRGGRQGSHHEQSVNRSGH 541
Query: 121 SGS-----SLQGASGSSQLGSSSSHSGS----SGSHSGSSSSHSSS----SSSFQFSSSS 167
SGS + QG S +S G S S S S + SG + HS S +SS SS
Sbjct: 542 SGSHHSHTTSQGRSDASH-GQSGSRSASRQTRNEEQSGDGTRHSGSRHHEASSQADSSRH 600
Query: 168 FQVGNG--SALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ 215
QVG G S T+ N + S S S+ + S+S S Q
Sbjct: 601 SQVGQGQSSGPRTSRNQGSSVSQDSDSQGHSEDSERWSGSASRNHHGSAQ 650
Score = 34.7 bits (78), Expect = 0.22
Identities = 55/207 (26%), Positives = 75/207 (36%), Gaps = 15/207 (7%)
Query: 58 GKGDSSGFSSYSGS-SSSGSSISSARSSGGGSSGSSSGSSIAQGGSAG----SFKPGTGY 112
G G +S SG SSGS S + G S S S++ G AG S + T
Sbjct: 2347 GHGQASSAVRDSGHRGSSGSQASDSE----GHSEDSDTQSVSAHGQAGPHQQSHQESTRG 2402
Query: 113 SQVSYSSGSGSSLQGASGSSQLGSSSSHSGSS-----GSHSGSSSSHSSSSSSFQFSSSS 167
S SGS L S Q S+ +G+S GSH + S S+S + +
Sbjct: 2403 RSAGRSGRSGSFLYQVSTHEQSESAHGRTGTSTGGRQGSHHKQARDSSRHSTSQEGQDTI 2462
Query: 168 FQVGNGSALPTNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQRPCSSDIPDSPC 227
S+ + Y +++ S S S T S S R S +
Sbjct: 2463 HGHPGSSSGGRQGSHYEQLVDRSGHSGSHHSHTTSQGRSDASHGHSGSRSASRQTRNDEQ 2522
Query: 228 SG-GPIVSHSGPYIPSSHSVSGGQRPV 253
SG G S S + SS + S G V
Sbjct: 2523 SGDGSRHSGSRHHEASSRADSSGHSQV 2549
Score = 34.3 bits (77), Expect = 0.29
Identities = 75/270 (27%), Positives = 103/270 (38%), Gaps = 36/270 (13%)
Query: 58 GKGDSSGF--SSYSGSSSSGSSISSARSS-----GGGSSGSSSGSSIAQGGSAGSFKPGT 110
G+ SSG S + GSS S S S S G +S + GSS Q GS PG
Sbjct: 1253 GQEQSSGSRTSRHQGSSVSQDSDSERHSDDSERLSGSASRNHHGSSREQSRD-GSRHPGF 1311
Query: 111 GYS-QVSYSSGSGSSLQGASGSSQLGSS----SSHS---GSSGSHSGSSSSHSSSSSSF- 161
+ S+ + SS Q + ++ S SSH S G GS S+ SS
Sbjct: 1312 HQEDRASHGHSADSSRQSGTHHTESSSHGQAVSSHEQARSSPGERHGSRHQQSADSSRHS 1371
Query: 162 -----QFSSS---SFQVGNGSALPTNDNSY---RGILNPSQPGQSSSSSQTFGVSSSGQS 210
Q SS+ S G+ + TN + + S GQ+ Q+ S+ GQS
Sbjct: 1372 GIGHRQASSAVRDSGHRGSSGSQVTNSEGHSEDSDTQSVSAHGQAGPHQQSHKESARGQS 1431
Query: 211 VSSNQRPCSSDIPDSPCSGGPIVSHSGPYIPSSHSVSGGQRPVVVVVDQHGSGAPG--VV 268
S+ R S S S G PS+ G + +H + G +
Sbjct: 1432 GESSGR--SRSFLYQVSSHEQSESTHGQTAPSTGGRQGSRHEQARNSSRHSASQDGQDTI 1489
Query: 269 QG-PPCSNGGLPGKPCPPITSVDKS-YGGY 296
+G P S GG G SVD+S + GY
Sbjct: 1490 RGHPGSSRGGRQGSYHE--QSVDRSGHSGY 1517
Score = 33.5 bits (75), Expect = 0.49
Identities = 49/177 (27%), Positives = 67/177 (37%), Gaps = 25/177 (14%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGS--SGSSSGSSIAQGGSAGSFKPGTGYSQ 114
+G G S+ S G S S A + G S S + S S+ Q GS + +
Sbjct: 2992 SGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGR 3051
Query: 115 VSYSSG-SGSSLQGASGSSQLGSSSSHSGSSGSHSG-SSSSHSSSSSSFQFSSSSFQVGN 172
+SG SGS L S Q S SSH + S G S H + S + S+S +
Sbjct: 3052 SGETSGHSGSFLYQVSTHEQ--SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQY---- 3105
Query: 173 GSALPTNDNSYRGILNPSQPGQSSSSSQTF----GVSSSGQSVSSNQRPCSSDIPDS 225
++ RG PG S Q + V SSG S S + S D+
Sbjct: 3106 ------GQDTIRG-----HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA 3151
Score = 32.0 bits (71), Expect = 1.4
Identities = 49/177 (27%), Positives = 66/177 (37%), Gaps = 25/177 (14%)
Query: 57 TGKGDSSGFSSYSGSSSSGSSISSARSSGGGS--SGSSSGSSIAQGGSAGSFKPGTGYSQ 114
+G G S+ S G S S A + G S S + S S+ Q GS + +
Sbjct: 2668 SGIGHGQASSAVRDSGHRGYSGSQASDNEGHSEDSDTQSVSAHGQAGSHQQSHQESARGR 2727
Query: 115 VSYSSG-SGSSLQGASGSSQLGSSSSHSGSSGSHSG-SSSSHSSSSSSFQFSSSSFQVGN 172
+SG SGS L S Q S SSH + S G S H + S + S+S
Sbjct: 2728 SGETSGHSGSFLYQVSTHEQ--SESSHGWTGPSTRGRQGSRHEQAQDSSRHSASQ----- 2780
Query: 173 GSALPTNDNSYRGILNPSQPGQSSSSSQTF----GVSSSGQSVSSNQRPCSSDIPDS 225
++ RG PG S Q + V SSG S S + S D+
Sbjct: 2781 -----DGQDTIRG-----HPGSSRGGRQGYHHEHSVDSSGHSGSHHSHTTSQGRSDA 2827
Score = 30.4 bits (67), Expect = 4.2
Identities = 35/158 (22%), Positives = 57/158 (36%), Gaps = 6/158 (3%)
Query: 62 SSGFSSYSGSSSSGSSISSARSSGGGSSGSSSGSSIAQGGSAGSFKPGT-GYSQ---VSY 117
S G++ S GS A+ S S+ +I G GS + G GY V
Sbjct: 2751 SHGWTGPSTRGRQGSRHEQAQDSSRHSASQDGQDTIR--GHPGSSRGGRQGYHHEHSVDS 2808
Query: 118 SSGSGSSLQGASGSSQLGSSSSHSGSSGSHSGSSSSHSSSSSSFQFSSSSFQVGNGSALP 177
S SGS + + +S SGS + + + S S S + + +
Sbjct: 2809 SGHSGSHHSHTTSQGRSDASRGQSGSRSASRTTRNEEQSGDGSRHSGSRHHEASTHADIS 2868
Query: 178 TNDNSYRGILNPSQPGQSSSSSQTFGVSSSGQSVSSNQ 215
+ + +G S+ + SS + S G S S +
Sbjct: 2869 RHSQAVQGQSEGSRRSRRQGSSVSQDSDSEGHSEDSER 2906
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.125 0.366
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 25,896,550
Number of Sequences: 37866
Number of extensions: 1585979
Number of successful extensions: 25718
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 414
Number of HSP's successfully gapped in prelim test: 978
Number of HSP's that attempted gapping in prelim test: 8501
Number of HSP's gapped (non-prelim): 7941
length of query: 529
length of database: 18,247,518
effective HSP length: 107
effective length of query: 422
effective length of database: 14,195,856
effective search space: 5990651232
effective search space used: 5990651232
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.