Guide to the Human Genome
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Search of human proteins with 67782346

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]
         (574 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]        1219   0.0  
gi|20149540 lysyl oxidase preproprotein [Homo sapiens]                357   1e-98
gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]             222   8e-58
gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]              216   5e-56
gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]             214   1e-55
gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]                53   9e-07
gi|239757043 PREDICTED: functional smad suppressing element 18 [...    52   1e-06
gi|239751555 PREDICTED: functional smad suppressing element 18 [...    52   1e-06
gi|239746067 PREDICTED: functional smad suppressing element 18 [...    52   1e-06
gi|210032580 SET domain containing 1B [Homo sapiens]                   50   6e-06
gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]            49   1e-05
gi|150417989 cyclin K isoform 1 [Homo sapiens]                         49   1e-05
gi|4758392 forkhead box D1 [Homo sapiens]                              49   1e-05
gi|18079216 CASK interacting protein 1 [Homo sapiens]                  48   2e-05
gi|11386183 WAS protein family, member 2 [Homo sapiens]                48   3e-05
gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming...    48   3e-05
gi|7706501 WW domain binding protein 11 [Homo sapiens]                 47   5e-05
gi|56118221 amyloid beta (A4) precursor protein-binding, family ...    47   6e-05
gi|162329583 cleavage and polyadenylation specific factor 6, 68 ...    46   8e-05
gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo s...    46   8e-05
gi|59806357 submaxillary gland androgen regulated protein 3 homo...    46   8e-05
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    46   8e-05
gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]        46   8e-05
gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]        46   8e-05
gi|146134388 YLP motif containing 1 [Homo sapiens]                     46   8e-05
gi|11415052 retinoid X receptor, beta [Homo sapiens]                   46   1e-04
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo...    46   1e-04
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ...    46   1e-04
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho...    46   1e-04
gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]     46   1e-04

>gi|67782346 lysyl oxidase-like 1 preproprotein [Homo sapiens]
          Length = 574

 Score = 1219 bits (3154), Expect = 0.0
 Identities = 574/574 (100%), Positives = 574/574 (100%)

Query: 1   MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE 60
           MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE
Sbjct: 1   MALARGSRQLGALVWGACLCVLVHGQQAQPGQGSDPARWRQLIQWENNGQVYSLLNSGSE 60

Query: 61  YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG 120
           YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG
Sbjct: 61  YVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFG 120

Query: 121 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP 180
           FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP
Sbjct: 121 FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP 180

Query: 181 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG 240
           QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG
Sbjct: 181 QAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGG 240

Query: 241 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA 300
           EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA
Sbjct: 241 EELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQA 300

Query: 301 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY 360
           HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY
Sbjct: 301 HGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVY 360

Query: 361 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL 420
           RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL
Sbjct: 361 RPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLL 420

Query: 421 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF 480
           RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF
Sbjct: 421 RFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASF 480

Query: 481 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK 540
           CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK
Sbjct: 481 CLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPK 540

Query: 541 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS 574
           YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS
Sbjct: 541 YIVLESDFTNNVVRCNIHYTGRYVSATNCKIVQS 574


>gi|20149540 lysyl oxidase preproprotein [Homo sapiens]
          Length = 417

 Score =  357 bits (917), Expect = 1e-98
 Identities = 172/268 (64%), Positives = 202/268 (75%), Gaps = 6/268 (2%)

Query: 308 GWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGR 367
           G  P  +N  P +       + PY P + SD  P     +  ++ R   G  YRP     
Sbjct: 149 GEVPALSNLRPPSRVDGMVGDDPYNPYKYSDDNPYYNYYDTYERPR--PGGRYRPGYGTG 206

Query: 368 ----GLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFP 423
               GLPDLV DP Y+QASTYVQ+  +Y+LRCAAEE CLASTAY  +  DYD RVLLRFP
Sbjct: 207 YFQYGLPDLVADPYYIQASTYVQKMSMYNLRCAAEENCLASTAYRADVRDYDHRVLLRFP 266

Query: 424 QRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLE 483
           QRVKNQGT+DFLP+RPR++WEWHSCHQHYHSMDEFSHYDLLDA T ++VAEGHKASFCLE
Sbjct: 267 QRVKNQGTSDFLPSRPRYSWEWHSCHQHYHSMDEFSHYDLLDANTQRRVAEGHKASFCLE 326

Query: 484 DSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIV 543
           D++CD+G  +R+ACT+HTQGLSPGCYDTY ADIDCQWIDITDV+PGNYILKV VNP Y+V
Sbjct: 327 DTSCDYGYHRRFACTAHTQGLSPGCYDTYGADIDCQWIDITDVKPGNYILKVSVNPSYLV 386

Query: 544 LESDFTNNVVRCNIHYTGRYVSATNCKI 571
            ESD+TNNVVRC+I YTG +  A+ C I
Sbjct: 387 PESDYTNNVVRCDIRYTGHHAYASGCTI 414



 Score = 61.6 bits (148), Expect = 2e-09
 Identities = 62/205 (30%), Positives = 83/205 (40%), Gaps = 27/205 (13%)

Query: 19  LCVLVH------GQQAQPGQG-SDPARWRQLIQWENNGQVYSLLNSGSEYVPAGPQRSES 71
           LC LVH      GQQ  P +  + P  WRQ IQWENNGQV+SLL+ GS+Y P   +R + 
Sbjct: 15  LCALVHCAPPAAGQQQPPREPPAAPGAWRQQIQWENNGQVFSLLSLGSQYQP--QRRRDP 72

Query: 72  SSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTV-----RGQARHPFGFGQVPD 126
            + V  A    AQQ R+     R    +       GS  V     R  ARH F  G    
Sbjct: 73  GAAVPGAANASAQQPRTPILLIRDNRTAAARTRTAGSSGVTAGRPRPTARHWFQAGYSTS 132

Query: 127 NWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVS 186
             RE       G +RA    +       ++    S         P  P ++     P+ +
Sbjct: 133 RARE------AGASRAENQTAPGEVPALSNLRPPSRVDGMVGDDPYNPYKYS-DDNPYYN 185

Query: 187 QYENYD---PASR---TYDQGFVYY 205
            Y+ Y+   P  R    Y  G+  Y
Sbjct: 186 YYDTYERPRPGGRYRPGYGTGYFQY 210


>gi|14211943 lysyl oxidase-like 3 precursor [Homo sapiens]
          Length = 753

 Score =  222 bits (565), Expect = 8e-58
 Identities = 109/202 (53%), Positives = 133/202 (65%), Gaps = 3/202 (1%)

Query: 371 DLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQG 430
           DL+     VQ + Y++   L+ L CAAEE CLAS+A +     Y  R LLRF  ++ N G
Sbjct: 530 DLLLHSALVQETAYIEDRPLHMLYCAAEENCLASSARSAN-WPYGHRRLLRFSSQIHNLG 588

Query: 431 TADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFG 490
            ADF P   RH+W WH CH HYHSMD F+HYD+L    G KVAEGHKASFCLED+ C   
Sbjct: 589 RADFRPKAGRHSWVWHECHGHYHSMDIFTHYDIL-TPNGTKVAEGHKASFCLEDTECQED 647

Query: 491 NLKRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFT 549
             KRY C +   QG++ GC+D Y  DIDCQWIDITDV+PGNYIL+V +NP + V ESDFT
Sbjct: 648 VSKRYECANFGEQGITVGCWDLYRHDIDCQWIDITDVKPGNYILQVVINPNFEVAESDFT 707

Query: 550 NNVVRCNIHYTGRYVSATNCKI 571
           NN ++CN  Y G  +   NC I
Sbjct: 708 NNAMKCNCKYDGHRIWVHNCHI 729


>gi|4505011 lysyl oxidase-like 2 precursor [Homo sapiens]
          Length = 774

 Score =  216 bits (550), Expect = 5e-56
 Identities = 107/230 (46%), Positives = 143/230 (62%), Gaps = 8/230 (3%)

Query: 344 GERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCL- 402
           GE     QG +  G+    ++     PDLV +   VQ +TY++   ++ L+CA EE CL 
Sbjct: 525 GEDVACPQGGVQYGAGVACSETA---PDLVLNAEMVQQTTYLEDRPMFMLQCAMEENCLS 581

Query: 403 ASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYD 462
           AS A     T Y  R LLRF  ++ N G +DF P   RH W WH CH+HYHSM+ F+HYD
Sbjct: 582 ASAAQTDPTTGY--RRLLRFSSQIHNNGQSDFRPKNGRHAWIWHDCHRHYHSMEVFTHYD 639

Query: 463 LLDAATGKKVAEGHKASFCLEDSTCDFGNLKRYACTSH-TQGLSPGCYDTYNADIDCQWI 521
           LL+   G KVAEGHKASFCLED+ C+    K Y C +   QG++ GC+D Y  DIDCQW+
Sbjct: 640 LLNL-NGTKVAEGHKASFCLEDTECEGDIQKNYECANFGDQGITMGCWDMYRHDIDCQWV 698

Query: 522 DITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSATNCKI 571
           DITDV PG+Y+ +V +NP + V ESD++NN+++C   Y G  +   NC I
Sbjct: 699 DITDVPPGDYLFQVVINPNFEVAESDYSNNIMKCRSRYDGHRIWMYNCHI 748


>gi|67782349 lysyl oxidase-like 4 precursor [Homo sapiens]
          Length = 756

 Score =  214 bits (546), Expect = 1e-55
 Identities = 121/258 (46%), Positives = 149/258 (57%), Gaps = 19/258 (7%)

Query: 322 GPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGL---------PDL 372
           G PRA E     VR S T         A Q     G V+  +  GR L         PDL
Sbjct: 483 GTPRAQEVVMSGVRCSGTEL-------ALQQCQRHGPVHCSHGGGRFLAGVSCMDSAPDL 535

Query: 373 VPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTA 432
           V +   VQ + Y++   L  L CA EE CL+ +A   +   Y  R LLRF  ++ N G  
Sbjct: 536 VMNAQLVQETAYLEDRPLSQLYCAHEENCLSKSADHMD-WPYGYRRLLRFSTQIYNLGRT 594

Query: 433 DFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDAATGKKVAEGHKASFCLEDSTCDFGNL 492
           DF P   R +W WH CH+HYHS++ F+HYDLL    G KVAEGHKASFCLED+ C  G  
Sbjct: 595 DFRPKTGRDSWVWHQCHRHYHSIEVFTHYDLL-TLNGSKVAEGHKASFCLEDTNCPTGLQ 653

Query: 493 KRYACTSH-TQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNN 551
           +RYAC +   QG++ GC+DTY  DIDCQW+DITDV PGNYI +V VNP Y V ESDF+NN
Sbjct: 654 RRYACANFGEQGVTVGCWDTYRHDIDCQWVDITDVGPGNYIFQVIVNPHYEVAESDFSNN 713

Query: 552 VVRCNIHYTGRYVSATNC 569
           +++C   Y G  V   NC
Sbjct: 714 MLQCRCKYDGHRVWLHNC 731


>gi|5032069 splicing factor 3b, subunit 4 [Homo sapiens]
          Length = 424

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 50/175 (28%), Positives = 59/175 (33%), Gaps = 30/175 (17%)

Query: 227 PYQPRARYEEYGGGEELPEYPPQGFYPAPERP----------YVPPPPPPPDGLDRRYSH 276
           P  P       G G   P  PP G +P P  P           +PPPP PP        H
Sbjct: 218 PSAPNPVVSSLGSGLPPPGMPPPGSFPPPVPPPGALPPGIPPAMPPPPMPPGAA----GH 273

Query: 277 SLYSEGT-----PGFEQAYPDPGPEAAQAHGGDPRL--------GWYPPYANPPPEAYGP 323
              S GT     PG   ++P P P     H G  ++        G   P+A PP    G 
Sbjct: 274 GPPSAGTPGAGHPGHGHSHPHPFPPGGMPHPGMSQMQLAHHGPHGLGHPHAGPPGSG-GQ 332

Query: 324 PRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNY 378
           P    PP +P      PP G    G   G         P    RG P L+P   Y
Sbjct: 333 PPPRPPPGMP--HPGPPPMGMPPRGPPFGSPMGHPGPMPPHGMRGPPPLMPPHGY 385



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 40/124 (32%), Positives = 44/124 (35%), Gaps = 15/124 (12%)

Query: 232 ARYEEYGGGEELPEYPPQGFYPAPERPY-VPPPPPPPDGLDRRYSHSLYSEGTPGFEQAY 290
           A +  +G G      P  G  P P  P  +P P PPP G+  R          P F    
Sbjct: 312 AHHGPHGLGHPHAGPPGSGGQPPPRPPPGMPHPGPPPMGMPPR---------GPPFGSPM 362

Query: 291 PDPGPEAAQAHGGDPRLGWYPP--YANPP-PEAYGPPRALEPPYLPVRSSDTPPPGGERN 347
             PGP       G P L   PP  Y  PP P  YG  R   PP  P      PP G  R 
Sbjct: 363 GHPGPMPPHGMRGPPPL--MPPHGYTGPPRPPPYGYQRGPLPPPRPTPRPPVPPRGPLRG 420

Query: 348 GAQQ 351
              Q
Sbjct: 421 PLPQ 424


>gi|239757043 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 996

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 79/331 (23%), Positives = 101/331 (30%), Gaps = 39/331 (11%)

Query: 159 SASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAA 218
           S  +F    ++ P     FP+P   F +    +    +  D G       G G G GA A
Sbjct: 387 SKGSFGGVLQKFPGCGGLFPHPYT-FPAAAAAFSLCHKKEDAGAAAEALGGAGAG-GAGA 444

Query: 219 VASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERP-------YVPPPPPPPDGLD 271
              AG+   + P  R + +        YPP   +  P  P       Y+ PPP PP  L 
Sbjct: 445 APKAGLSGLFWPAGRKDAF--------YPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALG 496

Query: 272 RRYSHSLYSEGTPGFEQAYPD---PGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALE 328
                    E      QA+ D   PG  A  A          PP   P   A GP     
Sbjct: 497 -----CALGESPALLRQAFLDLAEPGGAAGSAEAAP------PPGQPPQVVANGPGSGPP 545

Query: 329 PPYLPVRSSDT---PPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYV 385
           PP     S D     PPGG       G             G       P  + V A    
Sbjct: 546 PPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP--- 602

Query: 386 QRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEW 445
              HL   R A       S+A+ P     D   L +      + G        P H    
Sbjct: 603 HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKL--HGASAGAPHSAQTHPHHHHHP 660

Query: 446 HSCHQHYHSMDEFSHYDLLDAATGKKVAEGH 476
           H  H H+H     S   LL     +  +E H
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 46/186 (24%), Positives = 65/186 (34%), Gaps = 39/186 (20%)

Query: 138 GMARARTSVSQQRHGGS-----------ASSVSASAFASTYRQQPSYPQQFPYPQAPFVS 186
           G A +R ++ +   GGS           A SV+A+   +          + P P  P + 
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608

Query: 187 QYENYDPASRTYDQGFVYYRPAGGGVGAGAAAV---ASAGVIYPYQPRARYEEYGGGEEL 243
           +       S  +   F   RP GG   A + A    ASAG  +  Q    +  +      
Sbjct: 609 EGRKAGGGSYHHSSAF---RPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHH 665

Query: 244 PEYPPQG------------------FYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPG 285
             +PPQ                    +PAP  P  PPPPPPP      +   L S G  G
Sbjct: 666 HHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPP--PPPPPPPPLAQHPHHRGLLSPG--G 721

Query: 286 FEQAYP 291
              +YP
Sbjct: 722 TSCSYP 727



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 29/148 (19%)

Query: 208 AGGGVGAGAAAVASAGV----IYPYQPRARYEEYGGGEELPEYPP-QGFYPAPERPYVPP 262
           AG GVGAGA A A AG      YP  P      +GG   L ++P   G +P    PY  P
Sbjct: 358 AGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGG--VLQKFPGCGGLFP---HPYTFP 412

Query: 263 PPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGW--------YPPYA 314
                  L     H     G           G   A    G   L W        YPP+ 
Sbjct: 413 AAAAAFSL----CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFC 468

Query: 315 NPPPEAYGPPRALEPPYLPVRSSDTPPP 342
                 + PPR   P  LPV +   PPP
Sbjct: 469 -----MFWPPRT--PGGLPVPTYLQPPP 489


>gi|239751555 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 79/331 (23%), Positives = 101/331 (30%), Gaps = 39/331 (11%)

Query: 159 SASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAA 218
           S  +F    ++ P     FP+P   F +    +    +  D G       G G G GA A
Sbjct: 387 SKGSFGGVLQKFPGCGGLFPHPYT-FPAAAAAFSLCHKKEDAGAAAEALGGAGAG-GAGA 444

Query: 219 VASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERP-------YVPPPPPPPDGLD 271
              AG+   + P  R + +        YPP   +  P  P       Y+ PPP PP  L 
Sbjct: 445 APKAGLSGLFWPAGRKDAF--------YPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALG 496

Query: 272 RRYSHSLYSEGTPGFEQAYPD---PGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALE 328
                    E      QA+ D   PG  A  A          PP   P   A GP     
Sbjct: 497 -----CALGESPALLRQAFLDLAEPGGAAGSAEAAP------PPGQPPQVVANGPGSGPP 545

Query: 329 PPYLPVRSSDT---PPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYV 385
           PP     S D     PPGG       G             G       P  + V A    
Sbjct: 546 PPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP--- 602

Query: 386 QRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEW 445
              HL   R A       S+A+ P     D   L +      + G        P H    
Sbjct: 603 HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKL--HGASAGAPHSAQTHPHHHHHP 660

Query: 446 HSCHQHYHSMDEFSHYDLLDAATGKKVAEGH 476
           H  H H+H     S   LL     +  +E H
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 46/186 (24%), Positives = 64/186 (34%), Gaps = 39/186 (20%)

Query: 138 GMARARTSVSQQRHGGS-----------ASSVSASAFASTYRQQPSYPQQFPYPQAPFVS 186
           G A +R ++ +   GGS           A SV+A+   +          + P P  P + 
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608

Query: 187 QYENYDPASRTYDQGFVYYRPAGGGVGAGAAAV---ASAGVIYPYQPRARYEEYGGGEEL 243
           +       S  +   F   RP GG   A + A    ASAG  +  Q    +  +      
Sbjct: 609 EGRKAGGGSYHHSSAF---RPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHH 665

Query: 244 PEYPPQG------------------FYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPG 285
             +PPQ                    +PAP  P  PPPPPPP      +   L S G  G
Sbjct: 666 HHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPP--PPPPPPPPLAQHPHHRGLLSPG--G 721

Query: 286 FEQAYP 291
               YP
Sbjct: 722 TSCCYP 727



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 29/148 (19%)

Query: 208 AGGGVGAGAAAVASAGV----IYPYQPRARYEEYGGGEELPEYPP-QGFYPAPERPYVPP 262
           AG GVGAGA A A AG      YP  P      +GG   L ++P   G +P    PY  P
Sbjct: 358 AGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGG--VLQKFPGCGGLFP---HPYTFP 412

Query: 263 PPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGW--------YPPYA 314
                  L     H     G           G   A    G   L W        YPP+ 
Sbjct: 413 AAAAAFSL----CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFC 468

Query: 315 NPPPEAYGPPRALEPPYLPVRSSDTPPP 342
                 + PPR   P  LPV +   PPP
Sbjct: 469 -----MFWPPRT--PGGLPVPTYLQPPP 489


>gi|239746067 PREDICTED: functional smad suppressing element 18
           [Homo sapiens]
          Length = 1252

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 79/331 (23%), Positives = 101/331 (30%), Gaps = 39/331 (11%)

Query: 159 SASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAA 218
           S  +F    ++ P     FP+P   F +    +    +  D G       G G G GA A
Sbjct: 387 SKGSFGGVLQKFPGCGGLFPHPYT-FPAAAAAFSLCHKKEDAGAAAEALGGAGAG-GAGA 444

Query: 219 VASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERP-------YVPPPPPPPDGLD 271
              AG+   + P  R + +        YPP   +  P  P       Y+ PPP PP  L 
Sbjct: 445 APKAGLSGLFWPAGRKDAF--------YPPFCMFWPPRTPGGLPVPTYLQPPPQPPSALG 496

Query: 272 RRYSHSLYSEGTPGFEQAYPD---PGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALE 328
                    E      QA+ D   PG  A  A          PP   P   A GP     
Sbjct: 497 -----CALGESPALLRQAFLDLAEPGGAAGSAEAAP------PPGQPPQVVANGPGSGPP 545

Query: 329 PPYLPVRSSDT---PPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYV 385
           PP     S D     PPGG       G             G       P  + V A    
Sbjct: 546 PPAGGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAP--- 602

Query: 386 QRAHLYSLRCAAEEKCLASTAYAPEATDYDVRVLLRFPQRVKNQGTADFLPNRPRHTWEW 445
              HL   R A       S+A+ P     D   L +      + G        P H    
Sbjct: 603 HHPHLLEGRKAGGGSYHHSSAFRPVGGKDDAESLAKL--HGASAGAPHSAQTHPHHHHHP 660

Query: 446 HSCHQHYHSMDEFSHYDLLDAATGKKVAEGH 476
           H  H H+H     S   LL     +  +E H
Sbjct: 661 HHHHHHHHPPQPPSPLLLLPPQPDEPGSERH 691



 Score = 37.0 bits (84), Expect = 0.049
 Identities = 46/186 (24%), Positives = 64/186 (34%), Gaps = 39/186 (20%)

Query: 138 GMARARTSVSQQRHGGS-----------ASSVSASAFASTYRQQPSYPQQFPYPQAPFVS 186
           G A +R ++ +   GGS           A SV+A+   +          + P P  P + 
Sbjct: 549 GGAGSRDALFESPPGGSGGDCSAGSTPPADSVAAAGAGAAAAGSGPAGSRVPAPHHPHLL 608

Query: 187 QYENYDPASRTYDQGFVYYRPAGGGVGAGAAAV---ASAGVIYPYQPRARYEEYGGGEEL 243
           +       S  +   F   RP GG   A + A    ASAG  +  Q    +  +      
Sbjct: 609 EGRKAGGGSYHHSSAF---RPVGGKDDAESLAKLHGASAGAPHSAQTHPHHHHHPHHHHH 665

Query: 244 PEYPPQG------------------FYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPG 285
             +PPQ                    +PAP  P  PPPPPPP      +   L S G  G
Sbjct: 666 HHHPPQPPSPLLLLPPQPDEPGSERHHPAPPPP--PPPPPPPPLAQHPHHRGLLSPG--G 721

Query: 286 FEQAYP 291
               YP
Sbjct: 722 TSCCYP 727



 Score = 33.9 bits (76), Expect = 0.42
 Identities = 45/148 (30%), Positives = 52/148 (35%), Gaps = 29/148 (19%)

Query: 208 AGGGVGAGAAAVASAGV----IYPYQPRARYEEYGGGEELPEYPP-QGFYPAPERPYVPP 262
           AG GVGAGA A A AG      YP  P      +GG   L ++P   G +P    PY  P
Sbjct: 358 AGVGVGAGAGAGAGAGAKGPRSYPVIPVPSKGSFGG--VLQKFPGCGGLFP---HPYTFP 412

Query: 263 PPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGW--------YPPYA 314
                  L     H     G           G   A    G   L W        YPP+ 
Sbjct: 413 AAAAAFSL----CHKKEDAGAAAEALGGAGAGGAGAAPKAGLSGLFWPAGRKDAFYPPFC 468

Query: 315 NPPPEAYGPPRALEPPYLPVRSSDTPPP 342
                 + PPR   P  LPV +   PPP
Sbjct: 469 -----MFWPPRT--PGGLPVPTYLQPPP 489


>gi|210032580 SET domain containing 1B [Homo sapiens]
          Length = 1923

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 42/124 (33%), Positives = 44/124 (35%), Gaps = 44/124 (35%)

Query: 212 VGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLD 271
           V  GAAAVA+  V+ P               LP  PP GF P P     PPPPPPP    
Sbjct: 662 VTPGAAAVAAPSVLAP--------------TLPLPPPPGFPPLPP----PPPPPPPQ--- 700

Query: 272 RRYSHSLYSEGTPGFEQA--YPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEP 329
                       PGF      P P P    AH         P    PPP    PP    P
Sbjct: 701 ------------PGFPMPPPLPPPPPPPPPAH---------PAVTVPPPPLPAPPGVPPP 739

Query: 330 PYLP 333
           P LP
Sbjct: 740 PILP 743



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 22/77 (28%), Positives = 28/77 (36%), Gaps = 12/77 (15%)

Query: 257 RPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANP 316
           R   PPP PP + L +           PG     P P   + +  GG P  GW P   + 
Sbjct: 430 RAPAPPPLPPAEPLAKE---------KPGTPPGPPPPDTNSMEL-GGRPTFGWSPEPCDS 479

Query: 317 P--PEAYGPPRALEPPY 331
           P  P     P   E P+
Sbjct: 480 PGTPTLESSPAGPEKPH 496


>gi|6912582 penta-EF-hand domain containing 1 [Homo sapiens]
          Length = 284

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 40/111 (36%), Positives = 46/111 (41%), Gaps = 27/111 (24%)

Query: 214 AGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFY--PAPERPYVPPPPPPPDGLD 271
           AG A  A  G  YP  P +   +YG G      PP G Y  PAP  PY PP    P G  
Sbjct: 14  AGQAPGAPPGSYYPGPPNSG-GQYGSG-----LPPGGGYGGPAPGGPYGPPAGGGPYG-- 65

Query: 272 RRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYG 322
              +  ++  GTPG        GP    A GG        PY  PPP +YG
Sbjct: 66  -HPNPGMFPSGTPG--------GPYGGAAPGG--------PYGQPPPSSYG 99


>gi|150417989 cyclin K isoform 1 [Homo sapiens]
          Length = 580

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 43/138 (31%), Positives = 54/138 (39%), Gaps = 13/138 (9%)

Query: 208 AGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPP-- 265
           +G G  +  + + + G  Y   P A    YG    LP Y P  + P P  P VPPPP   
Sbjct: 440 SGEGYQSLQSMMKTEGPSYGALPPA----YGPPAHLP-YHPHVYPPNPPPPPVPPPPASF 494

Query: 266 PPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPR 325
           PP  +        Y    P +   +P P P     H   P     PP    PP +Y PP 
Sbjct: 495 PPPAIPPPTPG--YPPPPPTYNPNFPPPPPRLPPTHAVPPHP---PPGLGLPPASYPPP- 548

Query: 326 ALEPPYLPVRSSDTPPPG 343
           A+ P   P      PPPG
Sbjct: 549 AVPPGGQPPVPPPIPPPG 566



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 33/118 (27%), Positives = 44/118 (37%), Gaps = 19/118 (16%)

Query: 244 PEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLY--SEGTPGFEQAYPDPGPEAAQ-- 299
           P   P   +  P  P+ PPPPPP   +    + S Y   EG    +      GP      
Sbjct: 403 PPAHPAPVHQPPPLPHRPPPPPPSSYMTGMSTTSSYMSGEGYQSLQSMMKTEGPSYGALP 462

Query: 300 -AHGGDPRLGWYP--------------PYANPPPEAYGPPRALEPPYLPVRSSDTPPP 342
            A+G    L ++P              P A+ PP A  PP    PP  P  + + PPP
Sbjct: 463 PAYGPPAHLPYHPHVYPPNPPPPPVPPPPASFPPPAIPPPTPGYPPPPPTYNPNFPPP 520



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 59/227 (25%), Positives = 74/227 (32%), Gaps = 34/227 (14%)

Query: 169 QQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPY 228
           QQP  P   P PQ P V Q +    +  +  Q     +PA     A      S     P 
Sbjct: 274 QQP--PSLQPTPQVPQVQQSQPSQSSEPSQPQQKDPQQPAQQQQPAQQPKKPSPQPSSPR 331

Query: 229 QPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPP--PPPDGLDRRYSHSLYSEGTPGF 286
           Q +         E     PP    P  E  + P PP  PPPD   +    +   E  P  
Sbjct: 332 QVKRAVVVSPKEENKAAEPPPPKIPKIETTHPPLPPAHPPPDR--KPPLAAALGEAEP-- 387

Query: 287 EQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGER 346
                 PGP  A     D      PP A+P P    PP    PP         PPP    
Sbjct: 388 ------PGPVDAT----DLPKVQIPPPAHPAPVHQPPPLPHRPP--------PPPPSSYM 429

Query: 347 NGAQQGRLSVGSVYRPNQNGRGLPDLV--PDPNY-VQASTYVQRAHL 390
            G     +S  S Y   +  + L  ++    P+Y      Y   AHL
Sbjct: 430 TG-----MSTTSSYMSGEGYQSLQSMMKTEGPSYGALPPAYGPPAHL 471



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 28/97 (28%), Positives = 33/97 (34%), Gaps = 19/97 (19%)

Query: 171 PSYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQP 230
           P  P  FP P  P       Y P   TY+  F    P           +     + P+ P
Sbjct: 488 PPPPASFPPPAIP--PPTPGYPPPPPTYNPNFPPPPPR----------LPPTHAVPPHPP 535

Query: 231 RARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPP 267
                  G G     YPP    P  + P VPPP PPP
Sbjct: 536 P------GLGLPPASYPPPAVPPGGQPP-VPPPIPPP 565


>gi|4758392 forkhead box D1 [Homo sapiens]
          Length = 465

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 33/111 (29%), Positives = 43/111 (38%), Gaps = 16/111 (14%)

Query: 209 GGGVGAGAAAVASAGVIYPYQPRARYEEYGGGE-------ELPEY-PPQGFYPAPE---- 256
           G G   GA   A+A  ++P  P      YG G        +LP Y PP   + A      
Sbjct: 241 GAGAAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSALFAAAAAAAA 300

Query: 257 ----RPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGG 303
                P+ PPPPPPP G     + + +         A P P P +A   GG
Sbjct: 301 AAAFHPHSPPPPPPPHGAAAELARTAFGYRPHPLGAALPGPLPASAAKAGG 351



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 31/102 (30%), Positives = 37/102 (36%), Gaps = 27/102 (26%)

Query: 298 AQAHGGDPRLG--WYPPYANPPPEAYG-PPRALE-----PPYLPVRS------------- 336
           A    GDP      +PP   PPP AYG  P         PPY P  +             
Sbjct: 244 AAGGAGDPAAAAALFPPAPPPPPHAYGYGPYGCGYGLQLPPYAPPSALFAAAAAAAAAAA 303

Query: 337 ----SDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVP 374
               S  PPP      A+  R + G  YRP+  G  LP  +P
Sbjct: 304 FHPHSPPPPPPPHGAAAELARTAFG--YRPHPLGAALPGPLP 343


>gi|18079216 CASK interacting protein 1 [Homo sapiens]
          Length = 1431

 Score = 48.1 bits (113), Expect = 2e-05
 Identities = 70/285 (24%), Positives = 101/285 (35%), Gaps = 44/285 (15%)

Query: 77   LAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRGQARHPFGFGQVPDNWREVAVGDS 136
            + G  +A +R   G P  R  P+ P PGRV +     + +   G G    N R    G  
Sbjct: 1013 IGGGGRAARRPPEGHPTPR--PASPEPGRVATVLASVKHKEAIGPGGEVVNRRRTLSGPV 1070

Query: 137  TGMARARTSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYP-QAPFVSQYENYDPAS 195
            TG+       + +R  G ++         T RQ+P  P +     + P +++ E      
Sbjct: 1071 TGLL-----ATARRGPGESADPGPFVEDGTGRQRPRGPSKGEAGVEGPPLAKVEASATLK 1125

Query: 196  RTY---------------DQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPRARYE---EY 237
            R                 +   V  RP      AG        V +      R     E 
Sbjct: 1126 RRIRAKQNQQENVKFILTESDTVKRRPKAKEREAGPEPPPPLSVYHNGTGTVRRRPASEQ 1185

Query: 238  GGGEELPEYPPQGFYPAPERPYVPPPPPP-------------PDGLDRRYSHSLYSEGTP 284
             G  ELP  PP    P  +  ++PP PPP             P  +  +    L    TP
Sbjct: 1186 AGPPELPPPPPPAEPPPTDLAHLPPLPPPEGEARKPAKPPVSPKPVLTQPVPKLQGSPTP 1245

Query: 285  GFEQA-YPDPG-PEAAQAHGGDPRLGWYPPYANPPPEAYGPPRAL 327
              ++   P PG PE  +AHG  P +   PP   PPP A  P +A+
Sbjct: 1246 TSKKVPLPGPGSPEVKRAHGTPPPVSPKPP---PPPTAPKPVKAV 1287


>gi|11386183 WAS protein family, member 2 [Homo sapiens]
          Length = 498

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 55/208 (26%), Positives = 70/208 (33%), Gaps = 49/208 (23%)

Query: 144 TSVSQQRHGGSASSVSASAFASTYRQQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGFV 203
           T V Q    G   +V AS++       P        P   F        PA  +Y     
Sbjct: 227 TLVYQNGSIGCVENVDASSYPP-----PPQSDSASSPSPSFSEDNLPPPPAEFSY----- 276

Query: 204 YYRPAGGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPP- 262
              P     G+G A    + V+ P  P             P  PP G  P P+  + PP 
Sbjct: 277 ---PVDNQRGSGLAGPKRSSVVSPSHP-------------PPAPPLGSPPGPKPGFAPPP 320

Query: 263 --PPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEA 320
             PPPPP  +           G+PG     P P P +   H         P +A PPP  
Sbjct: 321 APPPPPPPMIGIPPPPPPVGFGSPG---TPPPPSPPSFPPH---------PDFAAPPPPP 368

Query: 321 YGPPRALEPPYLPVRSSDTPPPGGERNG 348
             PP A + P LP      PPP  +  G
Sbjct: 369 --PPPAADYPTLP------PPPLSQPTG 388


>gi|209180481 Cas-Br-M (murine) ecotropic retroviral transforming
           sequence-like 1 [Homo sapiens]
          Length = 491

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 43/142 (30%), Positives = 58/142 (40%), Gaps = 27/142 (19%)

Query: 230 PRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPG--FE 287
           P   + EY G + +  +P    +  P + +  PPPPPP  +     H   + GTP   + 
Sbjct: 315 PAHHHPEYQG-QPVVSHP---HHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYS 370

Query: 288 QAYPDPGPEAAQAHGGDPR--LGWYPPYAN------PPPEAYGPPRALEPPY------LP 333
           QA P P   A       P   +   PPY N      PPP+  GPP    PP+      LP
Sbjct: 371 QAPPPPMTSAPPPITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLP 430

Query: 334 VRSSD----TPP---PGGERNG 348
             + D    +PP   PGG   G
Sbjct: 431 QFTEDQGTLSPPFTQPGGMSPG 452



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 32/107 (29%), Positives = 36/107 (33%), Gaps = 19/107 (17%)

Query: 244 PEYPPQGFYPAPERPYV---PPPPPPPDG----LDRRYSHSLYSEGTPGFEQAYPDPGPE 296
           P  PP G   A   PY+   PP PPPP      +     H       P F +      P 
Sbjct: 383 PITPPPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPP 442

Query: 297 AAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPG 343
             Q  G  P +   P    PPP   GPP            S TP PG
Sbjct: 443 FTQPGGMSPGIWPAPRGPPPPPRLQGPP------------SQTPLPG 477


>gi|7706501 WW domain binding protein 11 [Homo sapiens]
          Length = 641

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 57/180 (31%), Positives = 69/180 (38%), Gaps = 25/180 (13%)

Query: 243 LPEYPPQGFYPAPE-RPYVPP---PPPPPDGLDRRYSHSLYSEGTPGFEQAYP---DPGP 295
           +P  PP G  PAP  RP  PP   PP PP G        L   G PG     P    PGP
Sbjct: 407 MPGPPPLGPPPAPPLRPPGPPTGLPPGPPPGA----PPFLRPPGMPGLRGPLPRLLPPGP 462

Query: 296 EAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLS 355
              +  G  P     PP   P P   GPP  L PP  P      PPP   R G    R  
Sbjct: 463 PPGRPPGPPP---GPPPGLPPGPPPRGPPPRLPPPAPP----GIPPP---RPGMM--RPP 510

Query: 356 VGSVYRPNQNGRGLPDLVPDPNYVQA-STYVQRAHLYSLRCAA-EEKCLASTAYAPEATD 413
           +     P   G   P  +P+P  + A    +QR        A  E+K  A+ +  P+ T+
Sbjct: 511 LVPPLGPAPPGLFPPAPLPNPGVLSAPPNLIQRPKADDTSAATIEKKATATISAKPQITN 570



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 14/33 (42%), Positives = 14/33 (42%)

Query: 311 PPYANPPPEAYGPPRALEPPYLPVRSSDTPPPG 343
           PP   PPP    P   L PP  P      PPPG
Sbjct: 405 PPMPGPPPLGPPPAPPLRPPGPPTGLPPGPPPG 437


>gi|56118221 amyloid beta (A4) precursor protein-binding, family B,
           member 1 interacting protein [Homo sapiens]
          Length = 666

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 35/110 (31%), Positives = 44/110 (40%), Gaps = 14/110 (12%)

Query: 250 GFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGW 309
           G  PAP   ++PPPPPPP   D            P F +  PD  P    ++ G      
Sbjct: 544 GGLPAPPDDFLPPPPPPPPLDDPE-----LPPPPPDFMEPPPDFVPPPPPSYAGIAGSEL 598

Query: 310 YPPYANPP-------PEAYGPPRAL--EPPYLPVRSSDTPPPGGERNGAQ 350
            PP   PP       P++  PP A+   PP  P R  +   PGG   G Q
Sbjct: 599 PPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQ 648


>gi|162329583 cleavage and polyadenylation specific factor 6, 68 kD
           subunit [Homo sapiens]
          Length = 551

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 44/139 (31%), Positives = 46/139 (33%), Gaps = 23/139 (16%)

Query: 242 ELPEYPPQGFYPAPERPYVPPPP----PPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEA 297
           + P  PP G  P P  P  PPPP    PPP              G P      P P    
Sbjct: 234 QTPPRPPLG-PPGPPGPPGPPPPGQVLPPP------------LAGPPNRGDRPPPPVLFP 280

Query: 298 AQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVG 357
            Q  G  P LG  PP   PP   YGPP    PP         PPP G       G L   
Sbjct: 281 GQPFG-QPPLGPLPPGPPPPVPGYGPPPGPPPP-----QQGPPPPPGPFPPRPPGPLGPP 334

Query: 358 SVYRPNQNGRGLPDLVPDP 376
               P  +  G P   P P
Sbjct: 335 LTLAPPPHLPGPPPGAPPP 353



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 34/98 (34%), Positives = 38/98 (38%), Gaps = 12/98 (12%)

Query: 246 YPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDP 305
           +P Q F   P  P  P PPPP  G           +G P      P PGP   +  G   
Sbjct: 279 FPGQPFGQPPLGPLPPGPPPPVPGYGPPPGPPPPQQGPP------PPPGPFPPRPPGP-- 330

Query: 306 RLGWYPPYA-NPPPEAYGPPRALEPPYLPVRSSDTPPP 342
            LG  PP    PPP   GPP    PP   V  +  PPP
Sbjct: 331 -LG--PPLTLAPPPHLPGPPPGAPPPAPHVNPAFFPPP 365


>gi|130492454 zinc finger RNA binding protein 2 isoform 1 [Homo
           sapiens]
          Length = 939

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 52/207 (25%), Positives = 72/207 (34%), Gaps = 40/207 (19%)

Query: 172 SYPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYPYQPR 231
           S+    P  QAP V   E+  PAS T   G+ Y          G    +SA ++  Y P 
Sbjct: 140 SHSHAQPPQQAPIV---ESGQPAS-TLSSGYTY------PTATGVQPESSASIVTSYPPP 189

Query: 232 ARYEEYGGGEELPEYP--PQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQA 289
           + Y         P YP      Y A    Y P  PPPP G  ++                
Sbjct: 190 S-YNPTCTAYTAPSYPNYDASVYSAASPFYPPAQPPPPPGPPQQL--------------- 233

Query: 290 YPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPP------- 342
              P P A    G  PR    PP  +  P     PR L+  Y  +       P       
Sbjct: 234 ---PPPPAPAGSGSSPRADSKPPLPSKLPRPKAGPRQLQLHYCDICKISCAGPQTYREHL 290

Query: 343 GGERNGAQQGRLSVGSVYRPNQNGRGL 369
           GG+++  ++     G   +PN + RG+
Sbjct: 291 GGQKHRKKEAAQKTG--VQPNGSPRGV 315


>gi|59806357 submaxillary gland androgen regulated protein 3 homolog
           A precursor [Homo sapiens]
          Length = 134

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 38/105 (36%), Positives = 42/105 (40%), Gaps = 17/105 (16%)

Query: 246 YPPQGFYPAPE------RPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDP--GPEA 297
           YPP    P P         +VPPP PPP G   R+   L     PG     P P  GP  
Sbjct: 30  YPPGPLAPPPPPCFPFGTGFVPPPHPPPYG-PGRFPPPLSPPYGPGRIPPSPPPPYGPGR 88

Query: 298 AQAHGGDPRLGWYPPYANPP--PEAYGPPRALEPPYLPVRSSDTP 340
            Q+H   P  G  P Y  PP  P  Y P     PP+ PV S   P
Sbjct: 89  IQSHSLPPPYG--PGYPQPPSQPRPYPP----GPPFFPVNSPTDP 127



 Score = 36.6 bits (83), Expect = 0.064
 Identities = 35/101 (34%), Positives = 40/101 (39%), Gaps = 14/101 (13%)

Query: 283 TPGFEQAYP----DPGPEAAQAHGGDPRLGWYPPYANPPPEAYGP---PRALEPPYLPVR 335
           TPG  Q  P     PGP A       P    + P  +PPP  YGP   P  L PPY P R
Sbjct: 18  TPGESQRGPRGPYPPGPLAPPPPPCFPFGTGFVPPPHPPP--YGPGRFPPPLSPPYGPGR 75

Query: 336 SSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
              +PPP         GR+   S+  P   G   P   P P
Sbjct: 76  IPPSPPP-----PYGPGRIQSHSLPPPYGPGYPQPPSQPRP 111


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 64/243 (26%), Positives = 84/243 (34%), Gaps = 37/243 (15%)

Query: 169 QQPSYPQQFPYPQAPFVSQYENYDPASRTYDQGF-VYYRPAGGGVGAGAAAVASAGVIYP 227
           QQP   Q  P+   P    ++   P     D    V  +  G   G G+A  AS+    P
Sbjct: 75  QQPPPQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP-P 133

Query: 228 YQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFE 287
             P       G G      PP     AP      PP PP  G+    +    + G P   
Sbjct: 134 ATPPTSGAPPGSGPGPTPTPPPAVTSAPPGAP--PPTPPSSGVP---TTPPQAGGPPPPP 188

Query: 288 QAYPDPGPEAAQAHG-GDPRLGWYP---------------PYANPPPEAYGPPRA---LE 328
            A P PGP   Q  G G P+ G  P                +  PP    G PR      
Sbjct: 189 AAVPGPGPGPKQGPGPGGPKGGKMPGGPKPGGGPGLSTPGGHPKPPHRGGGEPRGGRQHH 248

Query: 329 PPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRA 388
           PPY   +    PPPGG   G  + ++S    ++ N +      L+  P      TY QR 
Sbjct: 249 PPY-HQQHHQGPPPGGP-GGRSEEKISDSEGFKANLS------LLRRPG---EKTYTQRC 297

Query: 389 HLY 391
            L+
Sbjct: 298 RLF 300



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 36/138 (26%), Positives = 48/138 (34%), Gaps = 8/138 (5%)

Query: 210 GGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDG 269
           G +G G         I P  P  + ++    +  P+ PP    P   +P+    PPPP  
Sbjct: 45  GPMGPGPGQSGPKPPIPPPPPHQQQQQPPPQQPPPQQPPPHQPPPHPQPHQQQQPPPP-- 102

Query: 270 LDRRYSHSLYSEG---TPGFEQAYP--DPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPP 324
             +  S  + ++G    PG   A P     P A     G P      P   PPP     P
Sbjct: 103 -PQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSGAPPGSGPGPTPTPPPAVTSAP 161

Query: 325 RALEPPYLPVRSSDTPPP 342
               PP  P     T PP
Sbjct: 162 PGAPPPTPPSSGVPTTPP 179


>gi|195963316 PWWP domain containing 2A isoform b [Homo sapiens]
          Length = 755

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 253 PAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPP 312
           P  + P +PPPPPPP  L R  S           E+        AA A  G P L   P 
Sbjct: 61  PQADEPPLPPPPPPPGELAR--SPEAVGPELEAEEKLSVRVAESAAAAPQGGPELP--PS 116

Query: 313 YANPPPEAYGPPRALEPPY-LPVRSSDTPPPGGERNGAQ 350
            A+PP +   P    EPP   PV  +  PP GG+   +Q
Sbjct: 117 PASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQ 155


>gi|153791982 PWWP domain containing 2A isoform a [Homo sapiens]
          Length = 560

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 34/99 (34%), Positives = 42/99 (42%), Gaps = 5/99 (5%)

Query: 253 PAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPP 312
           P  + P +PPPPPPP  L R  S           E+        AA A  G P L   P 
Sbjct: 61  PQADEPPLPPPPPPPGELAR--SPEAVGPELEAEEKLSVRVAESAAAAPQGGPELP--PS 116

Query: 313 YANPPPEAYGPPRALEPPY-LPVRSSDTPPPGGERNGAQ 350
            A+PP +   P    EPP   PV  +  PP GG+   +Q
Sbjct: 117 PASPPEQPPAPEEREEPPLPQPVAPALVPPAGGDSTVSQ 155


>gi|146134388 YLP motif containing 1 [Homo sapiens]
          Length = 2146

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 40/126 (31%), Positives = 47/126 (37%), Gaps = 30/126 (23%)

Query: 243 LPEYPPQGFYPAPERPYVPPPPP---PPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQ 299
           LP  PP    P+   P +PP  P   PP G+             P    + P PG   + 
Sbjct: 530 LPTMPPPVLPPSLPPPVMPPALPATVPPPGMPPPVM-------PPSLPTSVPPPGMPPSL 582

Query: 300 AHGGDPRLGWYPPYANPPP--EAYGPPRALEPPY-----------LPVRSSDTPPPGGER 346
           +  G       PP   PPP   + GPP  L PP            LP  SS TPPPG   
Sbjct: 583 SSAG-------PPPVLPPPSLSSAGPPPVLPPPSLSSTAPPPVMPLPPLSSATPPPGIPP 635

Query: 347 NGAQQG 352
            G  QG
Sbjct: 636 PGVPQG 641



 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 47/174 (27%), Positives = 67/174 (38%), Gaps = 31/174 (17%)

Query: 241 EELPEYPP--QGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPD-----P 293
           E  PE PP   G Y  P + Y+PPP PPP       S        P   Q+ P      P
Sbjct: 144 ESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPTSSQPYLPPAQPSPSQSPPSQSYLAP 203

Query: 294 GPE-AAQAHGGDPRLGWYPPY-----ANP--PPEAYGPPRALEPPYLPVRSSDTPP--PG 343
            P  ++ +      L     Y     A+P  P + +   + L PP         PP  P 
Sbjct: 204 TPSYSSSSSSSQSYLSHSQSYLPSSQASPSRPSQGHSKSQLLAPP---------PPSAPP 254

Query: 344 GERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYV---QASTYVQRAHLYSLR 394
           G +   QQ  L  G+  +  +  +  P+  PDP+ +   +   Y  R HL SL+
Sbjct: 255 GNKTTVQQEPLESGAKNKSTEQQQAAPE--PDPSTMTPQEQQQYWYRQHLLSLQ 306



 Score = 40.8 bits (94), Expect = 0.003
 Identities = 31/109 (28%), Positives = 44/109 (40%), Gaps = 12/109 (11%)

Query: 244 PEYPPQGFYPAPERPYVPPPPPPPDGL----DRRYSHSL---YSEGTPGFEQAYPDPGPE 296
           P   P G Y   + P  P PPPP   L     ++Y H +     +G PG      +  PE
Sbjct: 89  PPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMLHHQRDGPPGLVPMELESPPE 148

Query: 297 AAQAHGGD---PRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPP 342
           +     G    P   + PP    PP +Y PP + +P   P + S +  P
Sbjct: 149 SPPVPPGSYMPPSQSYMPP--PQPPPSYYPPTSSQPYLPPAQPSPSQSP 195



 Score = 30.4 bits (67), Expect = 4.6
 Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 311 PPYANPPPEAYGPPRALEPPYLPVR-SSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGL 369
           PP   P   A  PP  + PP +P    +  PPPG   + +  G   V  +  P+ +  G 
Sbjct: 544 PPVMPPALPATVPPPGMPPPVMPPSLPTSVPPPGMPPSLSSAGPPPV--LPPPSLSSAGP 601

Query: 370 PDLVPDPN 377
           P ++P P+
Sbjct: 602 PPVLPPPS 609



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 41/154 (26%), Positives = 54/154 (35%), Gaps = 37/154 (24%)

Query: 237 YGGGEELPEYPPQGFYPAPERPYVPPPPP---PPDGLDRRYSHSL-----YSEGTPGFEQ 288
           YGG      YPP         P VPPPPP   P       YS S       S G   F +
Sbjct: 8   YGGSSH---YPP---------PPVPPPPPVALPEASPGPGYSSSTTPAAPSSSGFMSFRE 55

Query: 289 AYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGPPRAL--------EPPYLPVRSSDTP 340
            +     +  Q H    +    P +  PPP    PP  +        +PP  P+     P
Sbjct: 56  QHLAQLQQLQQMHQKQMQCVLQPHHLPPPP--LPPPPVMPGGGYGDWQPPPPPM----PP 109

Query: 341 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVP 374
           PPG   +  +Q +     ++       G P LVP
Sbjct: 110 PPGPALSYQKQQQYKHQMLHHQRD---GPPGLVP 140



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 19/53 (35%), Positives = 23/53 (43%), Gaps = 5/53 (9%)

Query: 295  PEAAQAHGGDPRLGWYPP---YANPPPEAYGPPRALEPPYLPVRSS--DTPPP 342
            P+ ++      R G YPP   Y  PPP    P   + P   P RSS   T PP
Sbjct: 1491 PQESRLQNTSSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSVPVTRPP 1543


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 33/107 (30%), Positives = 41/107 (38%), Gaps = 13/107 (12%)

Query: 244 PEYPPQGFYPAPERPYV------PPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEA 297
           P  PP    P    P +      PPPP PP  L   +     S G+PG     P P P  
Sbjct: 97  PPSPPGPPLPPSTAPSLGGSGAPPPPPMPPPPLGSPFPVISSSMGSPGL----PPPAPPG 152

Query: 298 AQAHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGG 344
                  P++       + P    GPP  ++PP L VR    PPP G
Sbjct: 153 FSGPVSSPQIN---STVSLPGGGSGPPEDVKPPVLGVRGLHCPPPPG 196


>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 22/153 (14%)

Query: 244 PEYPPQGFYPAPERPYVPPPP-----PPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAA 298
           P  PP G  P+  R  VPPPP     PP     R  + S      P   +  P P P ++
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 299 QAHGGDPRL--------GWYPPYAN-------PPPEAYGPPRALEPPYLPVRSSDTPPPG 343
             +   PRL           PP  +       PPP +  PP  +  P  P RS   PPP 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP--PGRSGPLPPPP 383

Query: 344 GERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
                    R    +   P+++G   P   P P
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 45/157 (28%), Positives = 58/157 (36%), Gaps = 41/157 (26%)

Query: 253 PAPERPYVPPP-----------PPPPDGLDRRYSHSLYSEGTP----GFEQAYPDPGP-- 295
           P P+R  +PPP           PPP     R    S ++ G+P    G  Q  P P P  
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 296 ----EAAQAHGGDPR---LGWYPPYANPPPEAYGPPRALE----PPYLPV-------RSS 337
                     GG  R   L    P++N PP    P RAL+    PP  PV       R +
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 338 DTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVP 374
             PPP       Q  +  V S  RP+ + +  P   P
Sbjct: 282 VPPPP------PQNNKPPVPSTPRPSASSQAPPPPPP 312



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 49/157 (31%), Positives = 54/157 (34%), Gaps = 32/157 (20%)

Query: 215 GAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPP-----------P 263
           G     S G   P  P  R    GGG  + + P     P   RP +PP           P
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 264 PPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGP 323
           PPPP G +R   H       P      P P      A    P     PP   PPP   GP
Sbjct: 267 PPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP-----PP--PPPPSRPGP 318

Query: 324 PRAL-------EPPYLPVR----SSDTPP-PGGERNG 348
           P          E P LP R    SS TPP P   R+G
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 35/137 (25%), Positives = 51/137 (37%), Gaps = 40/137 (29%)

Query: 240 GEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQ 299
           G + P   P+   P P+RP    PPPPP     R           GF+ +  +   E+  
Sbjct: 406 GVDSPRSGPRPPLP-PDRPSAGAPPPPPPSTSIR----------NGFQDSPCEDEWES-- 452

Query: 300 AHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSV 359
                 R  ++P    PPPE Y            V+++ + P    RN ++ G       
Sbjct: 453 ------RFYFHPISDLPPPEPY------------VQTTKSYPSKLARNESRSG------- 487

Query: 360 YRPNQNGRGLPDLVPDP 376
              N+  RG P L P P
Sbjct: 488 --SNRRERGAPPLPPIP 502


>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
           sapiens]
          Length = 503

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/153 (27%), Positives = 55/153 (35%), Gaps = 22/153 (14%)

Query: 244 PEYPPQGFYPAPERPYVPPPP-----PPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAA 298
           P  PP G  P+  R  VPPPP     PP     R  + S      P   +  P P P ++
Sbjct: 266 PPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPSRPGPPPLPPSS 325

Query: 299 QAHGGDPRL--------GWYPPYAN-------PPPEAYGPPRALEPPYLPVRSSDTPPPG 343
             +   PRL           PP  +       PPP +  PP  +  P  P RS   PPP 
Sbjct: 326 SGNDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPPSERPPPPVRDP--PGRSGPLPPPP 383

Query: 344 GERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
                    R    +   P+++G   P   P P
Sbjct: 384 PVSRNGSTSRALPATPQLPSRSGVDSPRSGPRP 416



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 45/157 (28%), Positives = 58/157 (36%), Gaps = 41/157 (26%)

Query: 253 PAPERPYVPPP-----------PPPPDGLDRRYSHSLYSEGTP----GFEQAYPDPGP-- 295
           P P+R  +PPP           PPP     R    S ++ G+P    G  Q  P P P  
Sbjct: 162 PEPQRNRMPPPRPDVGSKPDSIPPPVPSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP 221

Query: 296 ----EAAQAHGGDPR---LGWYPPYANPPPEAYGPPRALE----PPYLPV-------RSS 337
                     GG  R   L    P++N PP    P RAL+    PP  PV       R +
Sbjct: 222 FPGNRGTALGGGSIRQSPLSSSSPFSNRPPLPPTPSRALDDKPPPPPPPVGNRPSIHREA 281

Query: 338 DTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVP 374
             PPP       Q  +  V S  RP+ + +  P   P
Sbjct: 282 VPPPP------PQNNKPPVPSTPRPSASSQAPPPPPP 312



 Score = 37.7 bits (86), Expect = 0.029
 Identities = 49/157 (31%), Positives = 54/157 (34%), Gaps = 32/157 (20%)

Query: 215 GAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPP-----------P 263
           G     S G   P  P  R    GGG  + + P     P   RP +PP           P
Sbjct: 208 GGPRQPSPGPTPPPFPGNRGTALGGGS-IRQSPLSSSSPFSNRPPLPPTPSRALDDKPPP 266

Query: 264 PPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDPRLGWYPPYANPPPEAYGP 323
           PPPP G +R   H       P      P P      A    P     PP   PPP   GP
Sbjct: 267 PPPPVG-NRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAP-----PP--PPPPSRPGP 318

Query: 324 PRAL-------EPPYLPVR----SSDTPP-PGGERNG 348
           P          E P LP R    SS TPP P   R+G
Sbjct: 319 PPLPPSSSGNDETPRLPQRNLSLSSSTPPLPSPGRSG 355



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 35/137 (25%), Positives = 51/137 (37%), Gaps = 40/137 (29%)

Query: 240 GEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQ 299
           G + P   P+   P P+RP    PPPPP     R           GF+ +  +   E+  
Sbjct: 406 GVDSPRSGPRPPLP-PDRPSAGAPPPPPPSTSIR----------NGFQDSPCEDEWES-- 452

Query: 300 AHGGDPRLGWYPPYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSV 359
                 R  ++P    PPPE Y            V+++ + P    RN ++ G       
Sbjct: 453 ------RFYFHPISDLPPPEPY------------VQTTKSYPSKLARNESRSG------- 487

Query: 360 YRPNQNGRGLPDLVPDP 376
              N+  RG P L P P
Sbjct: 488 --SNRRERGAPPLPPIP 502


>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
           sapiens]
          Length = 1560

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 42/141 (29%), Positives = 55/141 (39%), Gaps = 17/141 (12%)

Query: 209 GGGVGAGAAAVASAGVIYPYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPP--P 266
           G G+G  A    ++    P  P A   +  G    P  P Q   P  + P++P P P  P
Sbjct: 742 GAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQA--PLGDSPHLPSPHPTRP 799

Query: 267 PDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGG----DPRLGWYPPYANPPPEAYG 322
           P    R  S        P     +P P P+A     G      +LG  PP +NP P A G
Sbjct: 800 PS---RPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPPPASNPAPTAPG 856

Query: 323 PPRALEPPYLPVRSSDTPPPG 343
           PP+       P+R    PP G
Sbjct: 857 PPQP------PLRPQSQPPEG 871



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 90/348 (25%), Positives = 116/348 (33%), Gaps = 73/348 (20%)

Query: 54  LLNSGSEYVPAGPQRSESSSRVLLAGAPQAQQRRSHGSPRRRQAPSLPLPGRVGSDTVRG 113
           LLN GS  V          ++ LL GAP  Q       P++  A    LP  VG   +  
Sbjct: 451 LLNQGSSIVIPAQHMLPGQNQFLLPGAPAVQ------LPQQLSA----LPANVGGQILAA 500

Query: 114 QARHPFG---FGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSVSASAFASTYRQQ 170
            A H  G      +  N + +A   S G   A  S +   H  SA+ +           Q
Sbjct: 501 AAPHTGGQLIANPILTN-QNLAGPLSLGPVLAPHSGAHSAHILSAAPIQVG--------Q 551

Query: 171 PS---YPQQFPYPQAPFVSQYENYDPASRTYDQGFVYYRPAGGGVGAGAAAVASAGVIYP 227
           P+    P        P  SQ     PA+ T  QG V   P+     A A      G++ P
Sbjct: 552 PALFQMPVSLAAGSLPTQSQPAPAGPAATTVLQG-VTLPPS-----AVAMLNTPDGLVQP 605

Query: 228 YQPRARYEEYGGGEELPEYPPQGFYPAPERPYVPPPPPPPDGLDRRYSHSLYSEGTPGFE 287
             P A       GE  P    Q   PAP+ P     P P  GL +  +       TP  +
Sbjct: 606 ATPAA-----ATGEAAPVLTVQ---PAPQAPPAVSTPLPL-GLQQPQAQQPPQAPTP--Q 654

Query: 288 QAYP----DPGPEAAQAHGGDPRLGWYPPYANP-------------PPEAYGPPRALEPP 330
            A P     P P    A   +  +   PP A P             P E    P + E P
Sbjct: 655 AAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQERSQQPLSAEGP 714

Query: 331 YLPVRSS---DTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPD 375
           +L V +S     PPP  +   A            P   G GL    PD
Sbjct: 715 HLSVPASVIVSAPPPAQDPAPA-----------TPVAKGAGLGPQAPD 751



 Score = 33.1 bits (74), Expect = 0.71
 Identities = 24/81 (29%), Positives = 28/81 (34%), Gaps = 22/81 (27%)

Query: 312  PYANPPPEAYGPPRALEPPYLPVRSSDTPPPGGERNGAQQ------------------GR 353
            P   PPP    PP  L+    P R    PPP G+ NG                      R
Sbjct: 1329 PVHQPPP----PPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAPHCPR 1384

Query: 354  LSVGSVYRPNQNGRGLPDLVP 374
            L +   YR N  G G P+  P
Sbjct: 1385 LPLRKTYRENVGGPGAPEGTP 1405



 Score = 30.0 bits (66), Expect = 6.0
 Identities = 12/23 (52%), Positives = 12/23 (52%)

Query: 247  PPQGFYPAPERPYVPPPPPPPDG 269
            PP       E P  PPPPPPP G
Sbjct: 1335 PPPATLKVAEPPPRPPPPPPPTG 1357


>gi|209571537 proline-rich protein BstNI subfamily 2 [Homo sapiens]
          Length = 416

 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 45/156 (28%), Positives = 56/156 (35%), Gaps = 26/156 (16%)

Query: 240 GEELPEYPPQGFYPAPE---RPYVPPPPP-PPDGLDRRYSHSLYSEGTPGFEQAYPDPG- 294
           G   P   PQG  P P+   +P  PPPPP  P G   +  +       PG  Q  P  G 
Sbjct: 49  GPPSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGD 106

Query: 295 -----------PEAAQAHGGDPRLGWYPPYA---NPPPEAYGPPRALEPPYLPVRSSDTP 340
                      P+     GG+   G  PP      PPP+    P+   PP  P      P
Sbjct: 107 KSRSPRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKP----QGP 162

Query: 341 PPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
           PP G+ N ++  R   G    P   G   P   P P
Sbjct: 163 PPQGD-NKSRSSRSPPGKPQGPPPQGGNQPQGPPPP 197



 Score = 42.7 bits (99), Expect = 9e-04
 Identities = 50/165 (30%), Positives = 57/165 (34%), Gaps = 35/165 (21%)

Query: 240 GEELPEYPPQGFYPAPE---RPYVPPPP-----PPPDGLDRRYSHSLYSEGTPGFEQAYP 291
           G   P   PQG  P P+   +P  PPPP     PPP G ++  S    S   PG  Q  P
Sbjct: 131 GPPPPPGKPQG--PPPQGGNKPQGPPPPGKPQGPPPQGDNKSRS----SRSPPGKPQGPP 184

Query: 292 DPG--------PEAAQAHGGDPRLGWYPPYANPPPEAYGPP--------RALEPPYLPVR 335
             G        P   +  G  P+ G  P    PP +  GPP         A  PP  P  
Sbjct: 185 PQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGDNKSQSARSPPGKP-- 242

Query: 336 SSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQ 380
               PP GG  N  Q      G    P   G   P   P P   Q
Sbjct: 243 -QGPPPQGG--NQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQ 284



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/170 (26%), Positives = 57/170 (33%), Gaps = 27/170 (15%)

Query: 227 PYQPRARYEEYGGGEELPEYPPQGFYPAPERPYVP--PPPPP--PDGLDRRYSHSLYSEG 282
           P  P  + +        P   PQG  P P+    P  PPPPP  P G   +  +      
Sbjct: 159 PQGPPPQGDNKSRSSRSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 216

Query: 283 TPGFEQAYPDPG-------------PEAAQAHGGDPRLGWYPPYA---NPPPEAYGPPRA 326
            PG  Q  P  G             P+     GG+   G  PP      PPP+    P+ 
Sbjct: 217 PPGKPQGPPPQGDNKSQSARSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 276

Query: 327 LEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
             PP  P      PP GG +  ++  R   G    P   G   P   P P
Sbjct: 277 PPPPGKP---QGPPPQGGSK--SRSSRSPPGKPQGPPPQGGNQPQGPPPP 321



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/170 (26%), Positives = 58/170 (34%), Gaps = 27/170 (15%)

Query: 227 PYQPRARYEEYGGGEELPEYPPQGFYPAPE---RPYVPPPPP-PPDGLDRRYSHSLYSEG 282
           P  P  + +        P   PQG  P P+   +P  PPPPP  P G   +  +      
Sbjct: 221 PQGPPPQGDNKSQSARSPPGKPQG--PPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQGPP 278

Query: 283 TPGFEQAYPDPG-------------PEAAQAHGGDPRLGWYPPYA---NPPPEAYGPPRA 326
            PG  Q  P  G             P+     GG+   G  PP      PPP+    P+ 
Sbjct: 279 PPGKPQGPPPQGGSKSRSSRSPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 338

Query: 327 LEPPYLPVRSSDTPPPGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDP 376
             PP  P      PP GG +  ++  R   G    P Q     P   P P
Sbjct: 339 PPPPGKP---QGPPPQGGSK--SRSARSPPGKPQGPPQQEGNNPQGPPPP 383



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 32/106 (30%), Positives = 41/106 (38%), Gaps = 12/106 (11%)

Query: 247 PPQGFYPAPERPYVPPPPP-PPDGLDRRYSHSLYSEGTPGFEQAYPDPGPEAAQAHGGDP 305
           PPQG      +P  PPPPP  P G   +  +       PG  Q  P  G   +++    P
Sbjct: 308 PPQG----GNQPQGPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPPQGGSKSRSARSPP 363

Query: 306 RLGWYPPYAN------PPPEAYGPPRALE-PPYLPVRSSDTPPPGG 344
                PP         PPP A G P+  + PP    +    PP GG
Sbjct: 364 GKPQGPPQQEGNNPQGPPPPAGGNPQQPQAPPAGQPQGPPRPPQGG 409



 Score = 29.6 bits (65), Expect = 7.9
 Identities = 27/91 (29%), Positives = 36/91 (39%), Gaps = 15/91 (16%)

Query: 295 PEAAQAHGGDPRLGWYPPYANPPPEAYGPP-----RALEPPYLPVRSSDTPPPGGER--- 346
           P+ A   GG+   G  PP  +PP +  GPP     +   PP  P +    PP GG +   
Sbjct: 36  PQGAPPQGGNKPQG--PP--SPPGKPQGPPPQGGNQPQGPPPPPGKPQGPPPQGGNKPQG 91

Query: 347 ---NGAQQGRLSVGSVYRPNQNGRGLPDLVP 374
               G  QG    G   R  ++  G P   P
Sbjct: 92  PPPPGKPQGPPPQGDKSRSPRSPPGKPQGPP 122


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.134    0.430 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,614,589
Number of Sequences: 37866
Number of extensions: 2020810
Number of successful extensions: 18218
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 163
Number of HSP's successfully gapped in prelim test: 758
Number of HSP's that attempted gapping in prelim test: 11173
Number of HSP's gapped (non-prelim): 4512
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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